Damien BREGEON

Publications

Article dans une revue (26)

Beyond RNA modification: a novel role for tRNA modifying enzyme in oxidative stress response and metabolism Louna Fruchard,Claudia Sudol,Caroline Rouard,Aurore Treffkorn-Maurau,Léo Hardyet al. Nucleic Acids Research, 2025, 53 (22), pp.gkaf1276. ⟨10.1093/nar/gkaf1276⟩ Article dans une revue pasteur-05438616v1
Functional redundancy in tRNA dihydrouridylation Claudia Sudol,Lea-Marie Kilz,V. Marchand,Quentin Thullier,Vincent Guérineauet al. Nucleic Acids Research, 2024, 52 (10), pp.5880-5894. ⟨10.1093/nar/gkae325⟩ Article dans une revue hal-04614743v1
Exploring a unique class of flavoenzymes: Identification and biochemical characterization of ribosomal RNA dihydrouridine synthase Sabrine Toubdji,Quentin Thullier,Lea-Marie Kilz,V. Marchand,Yifeng Yuanet al. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (32), pp.e2401981121. ⟨10.1073/pnas.2401981121⟩ Article dans une revue hal-04734945v1
Differential redox sensitivity of tRNA dihydrouridylation Lea-Marie Kilz,Simone Zimmermann,Virginie Marchand,Valérie Bourguignon,Claudia Sudolet al. Nucleic Acids Research, 2024, 52 (21), pp.12784-12797. ⟨10.1093/nar/gkae964⟩ Article dans une revue (article de synthèse) hal-04911631v1
DORQ-seq: high-throughput quantification of femtomol tRNA pools by combination of cDNA hybridization and Deep sequencing Marco Kristen,Marc Lander,Lea-Marie Kilz,Lukas Gleue,Marko Jörget al. Nucleic Acids Research, 2024, 52 (18), pp.e89. ⟨10.1093/nar/gkae765⟩ Article dans une revue hal-05357069v1
Evolutionary Diversity of Dus2 Enzymes Reveals Novel Structural and Functional Features among Members of the RNA Dihydrouridine Synthases Family Murielle Lombard,Colbie J Reed,Ludovic Pecqueur,Bruno Faivre,Sabrine Toubdjiet al. Biomolecules, 2022, 12 (12), pp.1760. ⟨10.3390/biom12121760⟩ Article dans une revue hal-04238858v1
Dihydrouridine in the transcriptome: New life for this ancient RNA chemical modification Damien Brégeon,Ludovic Pecqueur,Sabrine Toubdji,Claudia Sudol,Murielle Lombardet al. ACS Chemical Biology, 2022, 17 (7), pp.1638-1657. ⟨10.1021/acschembio.2c00307⟩ Article dans une revue hal-03836746v1
Dihydrouridine synthesis in tRNAs is under reductive evolution in Mollicutes Bruno Faivre,Murielle Lombard,Soufyan Fakroun,Chau-Duy-Tam Vo,Catherine Goyenvalleet al. RNA Biology, 2021, 18 (12), pp.2278 - 2289. ⟨10.1080/15476286.2021.1899653⟩ Article dans une revue hal-03837152v1
Reductive Evolution and Diversification of C5-Uracil Methylation in the Nucleic Acids of Mollicutes Pascal Sirand-Pugnet,Damien Brégeon,Laure Béven,Catherine Goyenvalle,Alain Blanchardet al. Biomolecules, 2020, 10 (4), pp.587. ⟨10.3390/biom10040587⟩ Article dans une revue hal-02547879v1
tRNA 2′-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila Margarita Angelova,Dilyana G Dimitrova,Bruno Da silva,Virginie Marchand,Caroline Jacquieret al. Nucleic Acids Research, 2020, 48 (4), pp.2050-2072. ⟨10.1093/nar/gkaa002⟩ Article dans une revue hal-02445153v1
Survey and Validation of tRNA Modifications and Their Corresponding Genes in Bacillus subtilis sp Subtilis Strain 168 Valerie de Crecy-Lagard,Robert J. Ross,Marshall Jaroch,Virginie Marchand,Christina Eisenhartet al. Biomolecules, 2020, 10 (7), pp.977. ⟨10.3390/biom10070977⟩ Article dans une revue hal-02915956v1
Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases Charles Bou-Nader,Damien Brégeon,Ludovic Pecqueur,Marc Fontecave,Djemel Hamdane Biochemistry, 2018, 57 (37), pp.5407-5414. ⟨10.1021/acs.biochem.8b00584⟩ Article dans une revue hal-01896983v1
Unveiling structural and functional divergences of bacterial tRNA dihydrouridine synthases: perspectives on the evolution scenario Charles Bou-Nader,Hugo Montémont,Vincent Guérineau,Olivier Jean-Jean,Damien Brégeonet al. Nucleic Acids Research, 2018, 46 (3), pp.1386-1394. ⟨10.1093/nar/gkx1294⟩ Article dans une revue hal-01727508v1
An extended dsRBD is required for post-transcriptional modification in human tRNAs Charles Bou-Nader,Ludovic Pecqueur,Damien Bregeon,Amina Kamah,Vincent Guérineauet al. Nucleic Acids Research, 2015, 43 (19), pp.9446-9456. ⟨10.1093/nar/gkv989⟩ Article dans une revue hal-01279196v1
Transcriptional mutagenesis: causes and involvement in tumour development Damien Brégeon,Paul Doetsch Nature Reviews Cancer, 2011, 11 (3), pp.218-227. ⟨10.1038/nrc3006⟩ Article dans une revue hal-03980890v1
A single methyltransferase YefA (RlmCD) catalyses both m5U747 and m5U1939 modifications in Bacillus subtilis 23S rRNA Benoit Desmolaize,Céline Fabret,Damien Brégeon,Simon Rose,Henri Grosjeanet al. Nucleic Acids Research, 2011, 39 (21), pp.9368-9375. ⟨10.1093/nar/gkr626⟩ Article dans une revue (data paper) hal-03978959v1
Transcriptional mutagenesis: causes and involvement in tumour development. Damien Brégeon,Paul W Doetsch Nature Reviews Cancer, 2011, 11 (3), pp.218-27. ⟨10.1038/nrc3006⟩ Article dans une revue hal-00574260v1
Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells. Damien Brégeon,Paul-Antoine Peignon,Alain Sarasin PLoS Genetics, 2009, 5 (7), pp.e1000577. ⟨10.1371/journal.pgen.1000577⟩ Article dans une revue hal-00408934v1
Transcriptional Mutagenesis Induced by 8-Oxoguanine in Mammalian Cells Damien Brégeon,Paul-Antoine Peignon,Alain Sarasin PLoS Genetics, 2009, 5 (7), pp.e1000577. ⟨10.1371/journal.pgen.1000577⟩ Article dans une revue hal-03980899v1
Thiazolinium and imidazolium chiral ionic liquids derived from natural amino acid derivatives D. Brégeon,Jocelyne Levillain,F. Guillen,Jean-Christophe Plaquevent,A.-C. Gaumont Amino Acids, 2008, 35 (1), pp.175. ⟨10.1007/s00726-007-0575-3⟩ Article dans une revue istex hal-01147106v1
Assays for Transcriptional Mutagenesis in Active Genes Damien Brégeon,Paul Doetsch Methods in Enzymology, 2006, Methods in Enzymology, 409, pp.345-357. ⟨10.1016/s0076-6879(05)09020-8⟩ Article dans une revue (data paper) hal-03979110v1
Hypothetical role of RNA damage avoidance in preventing human disease Damien Brégeon,Alain Sarasin Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005, 577 (1-2), pp.293-302. ⟨10.1016/j.mrfmmm.2005.04.002⟩ Article dans une revue (data paper) istex hal-03979122v1
Reliable method for generating double-stranded DNA vectors containing site-specific base modifications Damien Brégeon,Paul Doetsch Biotechniques, 2004, 37 (5), pp.760-766. ⟨10.2144/04375st01⟩ Article dans une revue (data paper) hal-03979129v1
Transcriptional Mutagenesis Induced by Uracil and 8-Oxoguanine in Escherichia coli Damien Brégeon,Zara Doddridge,Ho Jin You,Bernard Weiss,Paul Doetsch Molecular Cell, 2003, 12 (4), pp.959-970. ⟨10.1016/s1097-2765(03)00360-5⟩ Article dans une revue (data paper) hal-03979135v1
Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift Damien Brégeon,Vincent Colot,Miroslav Radman,François Taddei Genes and Development, 2001, 15 (17), pp.2295-2306. ⟨10.1101/gad.207701⟩ Article dans une revue (data paper) hal-03979139v1
Inefficient mismatch repair: genetic defects and down regulation Damien Brégeon,Ivan Matic,Miroslav Radman,François Taddei Journal of Genetics, 1999, 78 (1), pp.21-28. ⟨10.1007/BF02994699⟩ Article dans une revue (data paper) istex hal-03979141v1

Pré-publication, Document de travail (1)

tRNA 2'-O-methylation modulates small RNA silencing and life span in Drosophila Margarita T Angelova,Dilyana G Dimitrova,Bruno da Silva,Virginie Marchand,Catherine Goyenvalleet al. 2019 Pré-publication, Document de travail hal-02415561v1