Daniel Dory Scientific researcher (Principal Investigator) in avian virology, immunology, and vaccinology,

Identifiants chercheurs

IdHAL :

daniel-dory

ORCID :

0000-0003-0138-7713

Présentation

As a scientific researcher (Principal Investigator) in avian virology, immunology, and vaccinology, I contribute to the development of new tools for characterizing the immune response (humoral and cellular), the development and/or evaluation of vaccines, and studies on IBDV (Infectious bursal disease virus), avian coronaviruses, and avian metapneumoviruses.

This work is part of the WHOA (World Organization for Animal Health) reference laboratory on Infectious Bursal Disease (Gumboro Disease) and Turkey rhinotracheitis.

From 2002 to 2024, I was a project manager and team leader in swine immunology and virology, still at ANSES in Ploufragan. I specifically studied the efficacy and biosafety of DNA vaccination in pigs, using Aujeszky's disease (herpesvirus) as a reference model. I also participated in a study on foot-and-mouth disease vaccination in pigs and Campylobacter vaccination in chickens. The vaccine candidates were selected using the reverse vaccination strategy. Finally, I initiated antibody repertoire analysis studies in pigs as well as antigen-antibody modeling studies. I also participated in an assessment for the European marketing of a DNA vaccine for veterinary use by the European Medicines Agency.

Publications

Article dans une revue (9)

Reverse vaccinology: A strategy also used for identifying potential vaccine antigens in poultry Noémie Gloanec,Muriel Guyard-Nicodème,Marianne Chemaly,Daniel Dory Vaccine, 2025, 48, pp.126756. ⟨10.1016/j.vaccine.2025.126756⟩ Article dans une revue anses-04933934v1
Relevance of porcine intestinal organoids as a surrogate for animal experimentation: application to the investigation of host–virus interactions during porcine coronavirus infection Ludivine Percevault,Léon-Charles Tranchevent,Lionel Bigault,Maxime Berthaud,Damien Le Gloahecet al. Veterinary Research, 2025, 56 (1), pp.221. ⟨10.1186/s13567-025-01657-y⟩ Article dans une revue hal-05385997v1
Research Note: Analysis of immune responses in broilers after vaccination against Campylobacter jejuni Noémie Gloanec,Daniel Dory,Ségolène Quesne,Véronique Béven,Typhaine Poezevaraet al. Poultry Science, 2023, 102 (4), pp.102510. ⟨10.1016/j.psj.2023.102510⟩ Article dans une revue anses-04040798v1
Plasmid DNA Prime/Protein Boost Vaccination against Campylobacter jejuni in Broilers: Impact of Vaccine Candidates on Immune Responses and Gut Microbiota Noémie Gloanec,Muriel Guyard-Nicodème,Raphaël Brunetti,Ségolène Quesne,Alassane Keitaet al. Pharmaceutics, 2023, 15 (5), pp.1397. ⟨10.3390/pharmaceutics15051397⟩ Article dans une revue anses-04123731v1
Evaluation of Two Recombinant Protein-Based Vaccine Regimens against Campylobacter jejuni: Impact on Protection, Humoral Immune Responses and Gut Microbiota in Broilers Noémie Gloanec,Muriel Guyard-Nicodème,Raphaël Brunetti,Ségolène Quesne,Alassane Keitaet al. Animals, 2023, 13 (24), pp.3779. ⟨10.3390/ani13243779⟩ Article dans une revue anses-04350409v1
Terrorisme au Pérou : le Sentier Lumineux revisité par la géographie Daniel Dory,Hervé Théry Sécurité globale, 2022, N° 32 (4), pp.75-85. ⟨10.3917/secug.224.0075⟩ Article dans une revue halshs-03932011v1
Intranasal inoculations of naked or PLGA-PEI nanovectored DNA vaccine induce systemic and mucosal antibodies in pigs: A feasibility study Laurent Souci,Hervé Jaunet,Gérald Le Diguerher,Jean-Marie Guionnet,Véronique Bévenet al. Research in Veterinary Science, 2020, 132, pp.194-201. ⟨10.1016/j.rvsc.2020.06.018⟩ Article dans une revue hal-03093878v1
Targeted Collection of Plasmid DNA in Large and Growing Animal Muscles 6 Weeks after DNA Vaccination with and without Electroporation Daniel Dory,Vincent Le Moigne,Roland Cariolet,Véronique Béven,André Keranflecet al. Journal of Immunology Research, 2015 Article dans une revue hal-03715864v1
The protective immune response against Pseudorabies virus induced by DNA vaccination is impaired if the plasmid harbors a functional Porcine circovirus type 2 rep and origin of replication. Florence Faurez,Béatrice Grasland,Véronique Béven,Roland Cariolet,André Keranflec'Het al. Antiviral Research, 2012, 96 (3), pp.271-9. ⟨10.1016/j.antiviral.2012.09.024⟩ Article dans une revue istex inserm-00872623v1

Poster de conférence (2)

Contribution of intestinal porcine organoids to the study of host-virus interactions of transmissible gastroenteritis virus Ludivine Percevault,Lionel Bigault,Maxime Berthaud,Aurélie Leroux,Pierrick Lucaset al. Epizone, 16th annual meeting 2024, Sep 2024, Uppsala, Sweden. , pp.68, 2024 Poster de conférence anses-04834582v1
Apport des organoïdes porcins dans l’étude des interactions moléculaires hôtes-pathogènes du virus de la gastro-entérite transmissible Ludivine Percevault,Lionel Bigault,Maxime Berthaud,Aurélie Le Roux,Pierrick Lucaset al. XXVIes Journées francophones de virologie, Apr 2024, Liège, Belgique. 2024 Poster de conférence anses-04694301v1

Communication dans un congrès (2)

Evaluation des réponses immunitaires suite à la vaccination contre Campylobacter chez deux souches aviaires diffèrentes Noémie Gloanec,Muriel Guyard-Nicodème,Ségolène Quesne,Véronique Béven,Typhaine Poezevaraet al. 14èmes Journées de la Recherche Avicole et des Palmipèdes à Foie Gras, Mar 2022, Tours, France Communication dans un congrès anses-04082360v1
Immune responses and caecal microbiota composition in response to Campylobacter vaccination in poultry: 3 years of thesis in 3 minutes Noemie Gloanec,Muriel Guyard-Nicodème,Raphael Brunetti,Ségolène Quesne,Véronique Bévenet al. Journées Scientifiques et Doctorales de l'ANSES (JSDA) 2022, Oct 2022, Maisons-Alfort, France Communication dans un congrès anses-03855729v1