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Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging
Dorian Ziegler
,
David Vindrieux
,
Delphine Goehrig
,
Sara Jaber
,
Guillaume Collin
,
et al.
Article dans une revue
hal-04277344v1
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Calcium channel ITPR2 and mitochondria-ER contacts promote cellular senescence and aging
D. V. Ziegler
,
D. Vindrieux
,
D. Goehrig
,
S. Jaber
,
Guillaume Collin
,
et al.
Article dans une revue
inserm-03282710v1
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Regulation of cellular senescence by retinoid X receptors and their partners
Nadine Martin
,
Xingjie Ma
,
David Bernard
Article dans une revue
hal-02323512v1
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Hepatic Stellate Cell Senescence in Liver Tumorigenesis
Nadine Martin
,
Dorian Ziegler
,
Romain Parent
,
David Bernard
Article dans une revue
hal-03008992v1
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Generation of a conditional transgenic mouse model expressing human Phospholipase A2 Receptor 1
Sara Jaber
,
Delphine Goehrig
,
Philippe Bertolino
,
Amélie Massemin
,
Franck Bihl
,
et al.
Article dans une revue
inserm-02865473v1
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Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters
Lou Delval
,
Aline Hantute-Ghesquier
,
Valentin Sencio
,
Jean Michel Flaman
,
Cyril Robil
,
et al.
Article dans une revue
inserm-04170802v1
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Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape
C. Wiel
,
Baptiste Gras
,
David Vindrieux
,
Marine Warnier
,
Delphine Gitenay
,
et al.
Article dans une revue
hal-03144216v1
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MUC1 drives epithelial–mesenchymal transition in renal carcinoma through Wnt/β-catenin pathway and interaction with SNAIL promoter
Viviane Gnemmi
,
Audrey Bouillez
,
Kelly Gaudelot
,
Brigitte Hémon
,
Bélinda Ringot
,
et al.
Article dans une revue
hal-03313770v1
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The antioxidant N-acetylcysteine protects from lung emphysema but induces lung adenocarcinoma in mice
Marielle Breau
,
Amal Houssaini
,
Larissa Lipskaia
,
Shariq Abid
,
Emmanuelle Born
,
et al.
Article dans une revue
hal-02438202v1
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Depletion of preexisting B‐cell lymphoma 2‐expressing senescent cells before vaccination impacts antigen‐specific antitumor immune responses in old mice
Ozmen Cobanoglu
,
Lou Delval
,
Daniele Ferrari
,
Lucie Deruyter
,
Séverine Heumel
,
et al.
Article dans une revue
hal-04373734v1
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Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema
Alberta Palazzo
,
Gabriela Makulyte
,
Delphine Goerhig
,
Jean-Jacques Médard
,
Vincent Gros
,
et al.
Aging (Albany N.Y.), 2023
Article dans une revue
hal-04373654v1
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Regulation and role of calcium in cellular senescence
Nadine Martin
,
Kexin Zhu
,
Joanna Czarnecka-Herok
,
Mathieu Vernier
,
David Bernard
Article dans une revue
hal-04113402v1
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Cholesterol biosynthetic pathway induces cellular senescence through ERRα
Dorian Ziegler
,
Mathieu Vernier
,
Joanna Czarnecka-Herok
,
Charlotte Scholtes
,
Christelle Machon
,
et al.
2022
Pré-publication, Document de travail
hal-03516375v1
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The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes
Audrey Griveau
,
Clotilde Wiel
,
Dorian Ziegler
,
Martin Bergo
,
David Bernard
Article dans une revue
hal-03009024v1
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ORP5 Transfers Phosphatidylserine To Mitochondria And Regulates Mitochondrial Calcium Uptake At Endoplasmic Reticulum - Mitochondria Contact Sites
Leila Rochin
,
Cécile Sauvanet
,
Eeva Jääskeläinen
,
Audrey Houcine
,
Annukka Kivelä
,
et al.
Article dans une revue
hal-03128735v1
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PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging
Anda Huna
,
Audrey Griveau
,
David Vindrieux
,
Sara Jaber
,
Jean-Michel Flaman
,
et al.
Article dans une revue
inserm-03420490v1
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Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence
D Gitenay
,
C Wiel
,
H Lallet-Daher
,
D Vindrieux
,
S. Aubert
,
et al.
Article dans une revue
hal-03108285v1
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Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth
David Vindrieux
,
Guillaume Devailly
,
Arnaud Augert
,
Benjamin Le Calvé
,
Mylène Ferrand
,
et al.
Article dans une revue
hal-01867980v1
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Le traitement antioxydant protège contre l’emphysème mais favorise la survenue et la progression du cancer du poumon
Marielle Breau
,
David Bernard
,
Fatima Mechta-Grigoriou
,
Serge Adnot
Article dans une revue
hal-02903958v1
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Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors
Ikrame Naciri
,
Marthe Laisné
,
Laure Ferry
,
Morgane Bourmaud
,
Nikhil Gupta
,
et al.
Article dans une revue
pasteur-02071691v1
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Expression of the Calcium-Binding Protein CALB1 Is Induced and Controls Intracellular Ca2+ Levels in Senescent Cells
Clotilde Raynard
,
Nolwenn Tessier
,
Anda Huna
,
Marine Warnier
,
Jean-Michel Flaman
,
et al.
Article dans une revue
hal-03854772v1
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The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway
Marine Warnier
,
Jean-Michel Flaman
,
Christophe Chouabe
,
Clotilde Wiel
,
Baptiste Gras
,
et al.
Article dans une revue
hal-01847501v1
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PLA2R1 Mediates Tumor Suppression by Activating JAK2
David Vindrieux
,
Arnaud Augert
,
Christophe Girard
,
Delphine Gitenay
,
Helene Lallet-Daher
,
et al.
Article dans une revue
hal-02395807v1
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The PLA2R1-JAK2 pathway upregulates ERRα and its mitochondrial program to exert tumor-suppressive action
A Griveau
,
Guillaume Devailly
,
G Devailly
,
L Eberst
,
N Navaratnam
,
et al.
Article dans une revue
hal-01868807v1
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Evidence that SARS-CoV-2 Induces Lung-Cell Senescence: Potential Impact on COVID-19 Lung Disease
Larissa Lipskaia
,
Pauline Maisonnasse
,
Charles Fouillade
,
Valentin Sencio
,
Quentin Pascal
,
et al.
Article dans une revue
hal-03411265v1
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RSK3 switches cell fate: from stress-induced senescence to malignant progression
Anda Huna
,
Jean-Michel Flaman
,
Catalina Lodillinsky
,
Kexin Zhu
,
Gabriela Makulyte
,
et al.
Article dans une revue
hal-04373725v1
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Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A
Yajie Zhao
,
Zhichong Wu
,
Marie Chanal
,
Fabienne Guillaumond
,
Delphine Goehrig
,
et al.
Article dans une revue
hal-03008999v1
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Targeting chemoresistant senescent pancreatic cancer cells improves conventional treatment efficacy
Sara Jaber
,
Marine Warnier
,
Christopher Leers
,
Mathieu Vernier
,
Delphine Goehrig
,
et al.
Article dans une revue
hal-04113411v1
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Elimination of Senescent Endothelial Cells: Good or Bad Idea?
Nadine Martin
,
Anda Huna
,
David Bernard
Article dans une revue
inserm-03420580v1
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Extracellular AGR2 triggers lung tumour cell proliferation through repression of p21(CIP1)
Delphine Fessart
,
Claire de Barbeyrac
,
Ines Boutin
,
Thomas Grenier
,
Elodie Richard
,
et al.
Article dans une revue
hal-03102260v1
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