David Boulesteix

Researcher - Ingénieur Recherche à CentraleSupélec - Université Paris-Saclay
81 %
Libre accès
26
Documents

Présentation

Current - Juil. 2025: Research Engineer at CentraleSupélec-Paris-Saclay University.

  • Simulation of Titan, Mars, Europa, Enceladus environments under radiation to determine biosignatures survival and their interactions with minerals for long-term preservation and for complexification of prebiotic chemistry into biological cells.
  • Answering the question: What is the biosignature preservation potential of ocean world ices exposed to space-like combinations of temperature, pressure, and radiation? We are conducting a series of complicated, technically challenging experimental simulations to be conducted at cryogenic temperatures (~80 K), hard vacuum (10- 6 Torr), ice thicknesses of microns to 1 m, and sources of ionizing and UV radiation (100 keV electron, 192 keV X-ray, and 1 kW hydrogen Lyman-α/DUV source).
  • Sample treatments for chromatographic analysis of in situ organic matter at the surface of Titan (moon of Saturn) and Mars on Dragonfly, Curiosity, and Rosalind Franklin rovers.

Community engagements

  • GdR-PILSE (French consortium for return sample analysis): involved in (1) the analogue inventory and inter-laboratory comparison and (2) building up the analytical suite of analysis to optimize soluble organic matter from return samples.
  • Origin of the Life(s) (OoL): member of the scientific board team for scientific outreach and publications.
  • SpaceEthics: co-president of the association and international work-group supporting COSPAR on scientific and ethical questions of human cosmic footprints from past to future designed space activities (public and private).
  • Dragonfly, Mars Science Laboratory, and ExoMars missions scientists on the GC-MS instruments: involved to develop, test, and validate the engineering and spaceflight GC-MS instrumentations and in situ operations.

Publications: A. Normier, A. Boujibar, D. Boulesteix et al., 2025. A Call to Address Humanity's Cosmic Footprint, Nat. Astron. https://doi.org/10.1038/s41550-025-02606-7 A.J. Williams et al., 2026. Diverse Organic Molecules on Mars Revealed by the first SAM TMAH Experiment, Nat. Com. https://doi.org/10.1038/s41467-026-70656-0 S. Asche, C. Bautista, D. Boulesteix et al., 2025. What it takes to solve the Origin (s) of Life: An integrated review of techniques, Cell Reports Physical Science journal, https://doi.org/10.1016/j.xcrp.2026.103212 D. Boulesteix et al., 2025. New Analytical Methodology to Reveal Biosignatures on Mars and Ocean Worlds. AC-ACS. https://doi.org/10.1021/acs.analchem.5c01634 D. Boulesteix et al., 2024. Environmental Analogs from Yellowstone hot springs on Geochemical and Microbial Diversity with Implications for the Search for Life on Mars https://doi.org/10.1016/j.pss.2024.105953 D. Boulesteix et al., 2024. Using Derivatization with DMF-DMA Reagent for in situ Chiral Analyses of Organic Molecules on Titan with the DraMS Space Instrument, JCA Journal, https://doi.org/10.1016/j.chroma.2024.464860 C. Freissinet et al., 2024. Unveiling the Nitrogen Chemistry of Titan with the Dragonfly Mass Spectrometer: Experimental Focus on Amines and Amides, ACS Earth and Space Chemistry, https://doi.org/10.1021/acsearthspacechem.4c00143 D. Boulesteix et al., 2023. Comparison of TMAH, TMSH, or TMPAH Thermochemolysis for in situ Space Analyzes of Organic Molecules in Planetary Environments, Talanta Journal, https://doi.org/10.1016/j.talanta.2023.124283 Y. He, A. Buch, D. Boulesteix et al., 2023. The application of TMAH thermochemolysis on the detection of nucleotides: applications for the SAM and MOMA space experiments, JAAP Journal, https://doi.org/10.1016/j.jaap.2023.105933 D. Boulesteix et al., 2023. Influence of pH and Salts on DMF-DMA Derivatization for Future Space Applications, ACA Journal, https://doi.org/10.1016/j.aca.2023.341270 D. Boulesteix et al., 2023. Evaluation of the Interference of the Tenax® Adsorbents with DMF-DMA Reagent for MOMA and DraMS Analyzes, JCA Journal, https://doi.org/10.1016/j.chroma.2023.464388

Domaines de recherche

Planète et Univers [physics] Sciences de l'environnement Sciences du Vivant [q-bio] Sciences de l'ingénieur [physics]

Compétences

Analytical chemist (spectroscopy and mass spectrometry) astrobiologist biogeochemist organic chemist radiation physics closed reactor/systems microbiologist astrochemist oceanography metabolomics

Publications

Publications

Influence of Fe-Rich Materials on the Evolution of Amino Acids under Asteroidal Aqueous Alteration

Yuanyuan He , Laurent Remusat , Marceau Lecasble , David Boulesteix , Nadezda Khodorova et al.

ACS Earth and Space Chemistry, 2026, ⟨10.1021/acsearthspacechem.5c00193⟩

Article dans une revue hal-05562713v1

What it takes to solve the origins of life: An integrated review. Part 2: Theoretical methods and emerging trends

Silke Asche , Carla Bautista , Celia Blanco , David Boulesteix , Alexandre Champagne-Ruel et al.

Cell Reports Physical Science, 2026, pp.103211. ⟨10.1016/j.xcrp.2026.103211⟩

Article dans une revue (article de synthèse) hal-05591206v1
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Detection of nucleotides with gas chromatography – mass spectrometry (GC-MS) using trimethylsulfonium hydroxide (TMSH) and tetramethylammonium hydroxide (TMAH) thermochemolysis: Characterization, comparison and application to future experiments onboard space probes

Guillaume J Masson , Arnaud Buch , David Boulesteix , Caroline Freissinet , Melissa G Trainer et al.

Talanta, 2026, 305, pp.129684. ⟨10.1016/j.talanta.2026.129684⟩

Article dans une revue hal-05572918v1

What it takes to solve the origin of life: An integrated review. Part 1–Experimental methods and data repositories

Silke Asche , Carla Bautista , Celia Blanco , David Boulesteix , Alexandre Champagne-Ruel et al.

Cell Reports Physical Science, 2026, pp.103212. ⟨10.1016/j.xcrp.2026.103212⟩

Article dans une revue (article de synthèse) hal-05591203v1
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Site-specific D-H exchange of amino acids under asteroidal hydrothermal conditions

Yuanyuan He , Flavio Siro Brigiano , Michel Sablier , Nadezda Khodorova , David Boulesteix et al.

Geochimica et Cosmochimica Acta, 2025, 396, pp.170-181. ⟨10.1016/j.gca.2025.03.017⟩

Article dans une revue hal-05133605v1
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A Call to Address Humanity's Cosmic Footprint

Adrien Normier , Asmaa Boujibar , David Boulesteix , Oskari Sivula , Ian A Crawford et al.

Nature Astronomy, 2025, 9, pp.934-935. ⟨10.1038/s41550-025-02606-7⟩

Article dans une revue hal-05170293v1
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New analytical methodology to reveal biosignatures on Mars and Ocean worlds

David Boulesteix , Arnaud Buch , Guillaume Masson , Amy Williams , Valentin Moulay et al.

Analytical Chemistry, 2025, 97 (42), pp.23050-23061. ⟨10.1021/acs.analchem.5c01634⟩

Article dans une revue hal-05332782v1
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Dimethylformamide dimethyl acetal reagent for in situ chiral analyses of organic molecules on Titan with the Dragonfly mass spectrometer space instrument (Dragonfly mission)

D Boulesteix , A Buch , Jade Samson , Caroline Freissinet , David Coscia et al.

Journal of Chromatography A, 2024, 1722, pp.464860. ⟨10.1016/j.chroma.2024.464860⟩

Article dans une revue insu-04536914v2
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Environmental analogs from yellowstone hot springs on geochemical and microbial diversity with implications for the search for life on Mars

D Boulesteix , A Buch , G Masson , L L Kivrak , J R Havig et al.

Planetary and Space Science, 2024, 250 (October), pp.105953. ⟨10.1016/j.pss.2024.105953⟩

Article dans une revue insu-04672206v2
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Evolution of Nucleobases under Asteroidal Aqueous Alteration

Yuanyuan He , Laurent Rémusat , Marceau Lecasble , Jean-Christophe Viennet , Isis Criouet et al.

ACS Earth and Space Chemistry, 2024, 8 (9), pp.1820-1831. ⟨10.1021/acsearthspacechem.4c00132⟩

Article dans une revue hal-04690605v1
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The evolution of amino acids under asteroidal aqueous alteration

Yuanyuan He , Marceau Lecasble , Jean‐christophe Viennet , Isis Criouet , David Boulesteix et al.

Geochimica et Cosmochimica Acta, 2024, 387, pp.98-110. ⟨10.1016/j.gca.2024.09.035⟩

Article dans une revue hal-04753487v1
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Influence of pH and salts on DMF-DMA derivatization for future Space Applications

David Boulesteix , Arnaud Buch , J. Samson , Maeva Millan , J. Jomaa et al.

Analytica Chimica Acta, 2023, 1266, pp.341270. ⟨10.1016/j.aca.2023.341270⟩

Article dans une revue insu-04090927v1
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Comparison of tetramethylammonium hydroxide (TMAH), trimethylsulfonium hydroxide (TMSH), and trimethylphenylammonium hydroxide (TMPAH) thermochemolysis for in situ space analysis of organic molecules in planetary environments

David Boulesteix , Arnaud Buch , A.J. Williams , Y. He , Caroline Freissinet et al.

Talanta, 2023, 257 (May), pp.124283. ⟨10.1016/j.talanta.2023.124283⟩

Article dans une revue (article de synthèse) insu-03971903v1
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Evaluation of the Interference of Tenax®TA Adsorbent with Dimethylformamide Dimethyl Acetal Reagent for Gas Chromatography-Dragonfly Mass Spectrometry and Future Gas Chromatography-Mass Spectrometry in situ Analysis.

David Boulesteix , Arnaud Buch , N. Ruscassier , Caroline Freissinet , M.G. Trainer et al.

Journal of Chromatography A, 2023, 1709 (October), pp.464388. ⟨10.1016/j.chroma.2023.464388⟩

Article dans une revue insu-04212837v1
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Radiation-driven Prebiotic Chemistry and Biosignatures Detection

David Boulesteix , Arnaud Buch , Guillaume Masson , Cyril Szopa , Caroline Freissinet et al.

EPSC-DPS Joint Meeting 2025, Sep 2025, Helsinki, Finland. ⟨10.5194/epsc-dps2025-411⟩

Communication dans un congrès hal-05274095v1

Study of the influence of the secondary X-Rays on the organic matter at Mars' near-surface using synchrotron beam line

David Boulesteix

Abscicon 2024, May 2024, Providence (RI), Brown University, United States

Communication dans un congrès hal-04983671v1
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DraMS-like molecular extraction and analysis of Titan analog materials exposed to gamma and proton irradiations

D Boulesteix , A Buch , Cyril Szopa , Caroline Freissinet , S M Hörst et al.

55th LPSC Lunar and Planetary Science Conference 2024, Mar 2024, The Woodlands, United States. pp.LPI 2136

Communication dans un congrès insu-04465127v1
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Geochemical and Metabolomic study of few Yellowstone spring systems over a range of pH

David Boulesteix , Arnaud Buch , Amy J. Williams , Cyril Szopa , Victor Abrahamsson et al.

Life in the Sub Surface: Habitats, Species, Metabolism and Survival Strategies, Oct 2023, Angra do Heroismo, Portugal

Communication dans un congrès hal-04462918v1
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Development of the Dragonfly Mass Spectrometer (DraMS) for Titan

J. C. Stern , M. G. Trainer , W. B. Brinckerhoff , A. Grubisic , R. M. Danell et al.

54th LPSC Lunar and Planetary Science Conference 2023, Mar 2023, The Woodlands, United States. pp.LPI Contribution No. 2806, id.1667

Communication dans un congrès insu-04485408v1

Influence of the secondary X-Rays on the organic matter at Mars’ near-surface

Arnaud Buch , Cyril Szopa , Caroline Freissinet , David Boulesteix , Fabien Stalport et al.

AGU Fall Meeting 2023, Dec 2023, San Francisco (Califonia), United States

Communication dans un congrès insu-04366018v1

Understanding the Influence of the Secondary X-Rays on the Organic Matter at Mars' Near-Surface with the Soleil Synchrotron Beam Line LUCIA

Arnaud Buch , Caroline Freissinet , Cyril Szopa , Fabien Stalport , Sophie Nowak et al.

The Astrobiology Science Conference (AbSciCon) 2022, May 2022, Atlanta, United States. pp.id. 117-06

Communication dans un congrès insu-04483607v1

Influence of pH and salts on the DMF-DMA derivatization for GC-MS analysis of potential bioindicators on extraterrestrial surfaces (Mars, Titan, Europe, Enceladus,…)

David Boulesteix , Arnaud Buch , Jade Samson , Maëva Millan , Jamil Jomaa et al.

EJC, Oct 2022, Paris ( France), France

Communication dans un congrès hal-04462932v1
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Interpretation of SAM results simulating the Martian surface at SOLEIL synchrotron under X-ray irradiations

David Boulesteix , Arnaud Buch

The Astrobiology Science Conference (AbSciCon) 2022, May 2022, Atlanta, United States

Communication dans un congrès hal-04462906v1
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In Situ Analyses of Tholins Using DMF-DMA Derivatization For DraMS Instrument Onboard The Future Dragonfly Mission

David Boulesteix , Arnaud Buch , Cyril Szopa , Thomas Gautier , Caroline Freissinet et al.

The Astrobiology Science Conference (AbSciCon) 2022, May 2022, Atlanta, United States. pp.id. 204-06

Communication dans un congrès hal-04462898v1