David MOULIN

Identifiants chercheurs

IdHAL :

david-moulin

ORCID :

0000-0001-6619-5769

IdRef :

096283408

ResearcherID :

http://www.researcherid.com/rid/J-3849-2014

Présentation

Publications

Article dans une revue (48)

The role of the immune system in osteoarthritis: mechanisms, challenges and future directions David Moulin,Jérémie Sellam,Francis Berenbaum,Jérôme Guicheux,Marie-Astrid Boutet Nature Reviews Rheumatology, 2025, 21 (4), pp.221-236. ⟨10.1038/s41584-025-01223-y⟩ Article dans une revue (article de synthèse) hal-05063544v1
The adiponectin agonist AdipoRon accelerates osteoporosis development in two different models and modulates adipocyte differentiation Julia Halper,Sarah Nicolas,Federica Gilardi,Carine Winkler,Maria Materozziet al. BONE, 2025, 201, pp.117628. ⟨10.1016/j.bone.2025.117628⟩ Article dans une revue hal-05249446v1
Optimized GMP-grade Wharton’s jelly’s mesenchymal stromal cells manufacturing and administration protocol for Graft versus Host disease prevention Cécile Pochon,Romain Perouf,Anne-Béatrice Notarantonio,Allan Bertrand,Naceur Charifet al. Current Research in Translational Medicine, 2025, 73 (4), pp.103543. ⟨10.1016/j.retram.2025.103543⟩ Article dans une revue hal-05496220v1
Advanced combination therapy in inflammatory bowel disease Caroline Morizot,Léa Sequier,Jean-Yves Jouzeau,David Moulin,Patrick Netteret al. Joint Bone Spine, 2025, 92 (5), pp.105922. ⟨10.1016/j.jbspin.2025.105922⟩ Article dans une revue hal-05379217v1
Dysregulated myeloid differentiation in colitis is induced by inflammatory osteoclasts in a TNFα-dependent manner Maria Bernadette Madel,Lidia Ibáñez,Thomas Ciucci,Julia Halper,Antoine Boutinet al. Mucosal Immunology, 2025, 18 (1), pp.90-104. ⟨10.1016/j.mucimm.2024.09.005⟩ Article dans une revue hal-04758665v1
Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4+ T cells to confer protection against intestinal inflammation Qing Li,Rodrigo de Oliveira Formiga,Virginie Puchois,Laura Creusot,Ahmad Haidar Ahmadet al. Nature Metabolism, 2025, 7 (12), pp.2510-2530. ⟨10.1038/s42255-025-01396-6⟩ Article dans une revue pasteur-05390470v1
Counteracting tryptophan metabolism alterations as a new therapeutic strategy for rheumatoid arthritis David Moulin,Marie Millard,Mahdia Taïeb,Chloé Michaudel,Anne Aucouturieret al. Annals of the Rheumatic Diseases, 2024, 83 (3), pp.312-323. ⟨10.1136/ard-2023-224014⟩ Article dans une revue hal-04307521v1
Deciphering natural killer cell cytotoxicity against medulloblastoma in vitro and in vivo: Implications for immunotherapy Mélanie Gauthier,Julien Pierson,David Moulin,Manon Mouginot,Valérie Bourguignonet al. ImmunoTargets and Therapy, 2024, 13, pp.319-333. ⟨10.2147/itt.s458278⟩ Article dans une revue hal-04634070v1
Identification of circulating biomarkers of Crohn's disease and spondyloarthritis using Fourier transform infrared spectroscopy Pierre Prada,Benjamin Brunel,David Moulin,Lise Rouillon,Patrick Netteret al. Journal of Biophotonics, 2023, 16 (2), pp.e202200200. ⟨10.1002/jbio.202200200⟩ Article dans une revue hal-04168372v1
Impact of the Exposome on the Epigenome in Inflammatory Bowel Disease Patients and Animal Models Sophie Vieujean,Bénédicte Caron,Vincent Haghnejad,Jean-Yves Jouzeau,Patrick Netteret al. International Journal of Molecular Sciences, 2022, 23 (14), pp.7611. ⟨10.3390/ijms23147611⟩ Article dans une revue hal-03857407v1
Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases Chloé Michaudel,Camille Danne,Allison Agus,Aurélie Magniez,Anne Aucouturieret al. Gut, 2022, 1-12, pp.gutjnl-2022-327337. ⟨10.1136/gutjnl-2022-327337⟩ Article dans une revue hal-03859817v2
Emerging role of IκBζ in inflammation: Emphasis on psoriasis Preeti Gautam,Sylvain Maenner,Frédéric Cailotto,Pascal Reboul,Stéphane Labialleet al. Clinical and Translational Medicine, 2022, 12 (10), pp.e1032. ⟨10.1002/ctm2.1032⟩ Article dans une revue hal-03859806v1
Anti-Inflammatory Activity of Bryophytes Extracts in LPS-Stimulated RAW264.7 Murine Macrophages Raíssa Volpatto Marques,Stefania Enza Sestito,Frédéric Bourgaud,Sissi Miguel,Frédéric Cailottoet al. Molecules, 2022, 27 (6), pp.1940. ⟨10.3390/molecules27061940⟩ Article dans une revue hal-03652855v1
Long-Term Overconsumption of Fat and Sugar Causes a Partially Reversible Pre-inflammatory Bowel Disease State Djésia Arnone,Marie Vallier,Sébastien Hergalant,Caroline Chabot,Ndeye Coumba Ndiayeet al. Frontiers in Nutrition, 2021, 8, pp.758518. ⟨10.3389/fnut.2021.758518⟩ Article dans une revue hal-03430881v1
Lack of Adiponectin Drives Hyperosteoclastogenesis in Lipoatrophic Mice Maria-Bernadette Madel,He Fu,Dominique D Pierroz,Mariano Schiffrin,Carine Winkleret al. Frontiers in Cell and Developmental Biology, 2021, 9, pp.627153. ⟨10.3389/fcell.2021.627153⟩ Article dans une revue hal-03356534v1
Lack of protective effect of CCR3 blockade during experimental colitis may be related to CCR3 expression by colonic Tregs Maroua Ferhat,Julie Hablot,Mahdia Taieb,Fatouma Salem,Patrick Netteret al. Clinical and Translational Medicine, 2021, 11 (6), pp.e455. ⟨10.1002/ctm2.455⟩ Article dans une revue hal-03356573v1
Identification of TGFβ signatures in six murine models mimicking different osteoarthritis clinical phenotypes Marie Maumus,Danièle Noël,Hang Korng Ea,David Moulin,Maxime Ruizet al. Osteoarthritis and Cartilage, 2020, 28 (10), pp.1373-1384. ⟨10.1016/j.joca.2020.06.008⟩ Article dans une revue hal-02899374v1
Mast cells in spondyloarthritis, more than simple inflammatory bystanders? Laura Polivka,Laurent Frenzel,Jean-Yves Jouzeau,Olivier Hermine,David Moulin Therapeutic advances in musculoskeletal disease, 2020, 12, pp.1759720X2097190. ⟨10.1177/1759720X20971907⟩ Article dans une revue hal-03090864v1
Tofacitinib treatment alters mucosal immunity and gut microbiota during experimental arthritis Julie Hablot,Maroua Ferhat,Aonghus Lavelle,Fatouma Salem,Mahdia Taiebet al. Clinical and Translational Medicine, 2020, 10 (5), pp.e163. ⟨10.1002/ctm2.163⟩ Article dans une revue hal-03005532v1
Paradoxical gastrointestinal effects of interleukin-17 blockers Marine Fauny,David Moulin,Ferdinando d'Amico,Patrick Netter,Nadine Petitpainet al. Annals of the Rheumatic Diseases, 2020, 79 (9), pp.1132 - 1138. ⟨10.1136/annrheumdis-2020-217927⟩ Article dans une revue hal-02920284v1
Metabolic regulation by PPARγ is required for IL-33-mediated activation of ILC2s in lung and adipose tissue Tinhinane Fali,Tegest Aychek,Maroua Ferhat,Jean-Yves Jouzeau,Meinrad Busslingeret al. Mucosal Immunology, 2020, 14 (3), pp.585-593. ⟨10.1038/s41385-020-00351-w⟩ Article dans une revue hal-03005537v1
Gut microbiome in Chronic Rheumatic and Inflammatory Bowel Diseases: similarities and differences Fatouma Salem,Nadège Kindt,Julian R. Marchesi,Patrick Netter,Anthony Lopezet al. United European Gastroenterology Journal, 2019, 7 (8), pp.1008-1032. ⟨10.1177/2050640619867555⟩ Article dans une revue hal-02192635v1
Zinc-Alpha-2-Glycoprotein in Inflammatory Bowel Disease Véronique Rolli,Cécile Macquin,Tunay Kokten,Julie Hablot,Ndeye-Coumba Ndiayeet al. Inflammatory Bowel Diseases, 2018, 24 (5), pp.e10. ⟨10.1093/ibd/izy120⟩ Article dans une revue hal-02401061v1
Lack of Adipocytes Alters Hematopoiesis in Lipodystrophic Mice Anne Wilson,Mariano Schiffrin,Carine Winkler,Meriem Koufany,Jean-Yves Jouzeauet al. Frontiers in Immunology, 2018, 9, pp.2573. ⟨10.3389/fimmu.2018.02573⟩ Article dans une revue hal-02401054v1
L’interdisciplinarité au service de l’environnement (Journée d’études, université d’Artois, Arras, 3 février 2017) Olivier Petit,Jacques Coget,Christelle Hinnewinkel,David Moulin,Virginie Vergneet al. Natures Sciences Sociétés, 2018, Natures Sciences Sociétés, 26 (1), pp.92-97. ⟨10.1051/nss/2018026⟩ Article dans une revue hal-02611207v2
Response to: ‘Spontaneous hypertensive rat exhibits bone and meniscus phenotypes of osteoarthritis: is it an appropriate control for MetS-associated OA?’ by Chan and Wen Chaohua Deng,Arnaud Bianchi,Nathalie Presle,David Moulin,Meriem Koufanyet al. Annals of the Rheumatic Diseases, 2018, 77 (5), pp.e26-e26. ⟨10.1136/annrheumdis-2017-212003⟩ Article dans une revue hal-02983106v1
Eplerenone treatment alleviates the development of joint lesions in a new rat model of spontaneous metabolic-associated osteoarthritis Chaohua Deng,Arnaud Bianchi,Nathalie Presle,David Moulin,Meriem Koufanyet al. Annals of the Rheumatic Diseases, 2018, 77 (2), pp.315 - 316. ⟨10.1136/annrheumdis-2016-210700⟩ Article dans une revue hal-01702028v1
TREM-1 Inhibition Restores Impaired Autophagy Activity and Reduces Colitis in Mice Tunay Kokten,Sébastien Gibot,Patricia Lepage,Silvia D 'Alessio,Julie Hablotet al. Journal of Crohn's and Colitis, 2018, 12 (2), pp.230-244. ⟨10.1093/ecco-jcc/jjx129⟩ Article dans une revue hal-01715133v1
Management of patients with inflammatory bowel disease and spondyloarthritis Lieven Pouillon,Peter Bossuyt,Joke Vanderstukken,David Moulin,Patrick Netteret al. Expert Review of Clinical Pharmacology, 2017, 10 (12), pp.1363-1374. ⟨10.1080/17512433.2017.1377609⟩ Article dans une revue hal-01715137v1
Experimental colitis delays and reduces the severity of collagen-induced arthritis in mice Julie Hablot,Laurent Peyrin-Biroulet,Tunay Kokten,Reine El Omar,Patrick Netteret al. PLoS ONE, 2017, 12 (9), pp.e0184624. ⟨10.1371/journal.pone.0184624⟩ Article dans une revue hal-01618133v1
Review article: moving towards common therapeutic goals in Crohn's disease and rheumatoid arthritis P B Allen,P. Olivera,P. Emery,D. Moulin,J.-Y. Jouzeauet al. Alimentary Pharmacology & Therapeutics, 2017, 45 (8), pp.1058 - 1072. ⟨10.1111/apt.13995⟩ Article dans une revue hal-01715552v1
MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes David Moulin,Veronique Salone,Meriem Koufany,Thomas Clément,Isabelle Behm-Ansmantet al. BioMed Research International , 2017, 2017, pp.1 - 12. ⟨10.1155/2017/9792512⟩ Article dans une revue hal-01704545v1
Association between rheumatoid arthritis and systemic mastocytosis: a case report and literature review Ichraq Latar,Meriem Koufany,Julie Hablot,Damien Loeuille,Patrick Netteret al. Clinical Rheumatology, 2016, 35 (10), pp.2619-2623. ⟨10.1007/s10067-016-3368-9⟩ Article dans une revue hal-01715226v1
Label-free relative quantification applied to LC-MALDI acquisition for rapid analysis of chondrocyte secretion modulation Mathieu Riffault,David Moulin,Laurent Grossin,Didier Mainard,Jacques Magdalouet al. Journal of Proteomics, 2015, 114, pp.263-273. ⟨10.1016/j.jprot.2014.10.026⟩ Article dans une revue hal-01451913v1
Fenofibrate vs pioglitazone: Comparative study of the anti-arthritic potencies of PPAR-alpha and PPAR-gamma agonists in rat adjuvant-induced arthritis Meriem Koufany,Jean-Yves Jouzeau,David Moulin Bio-Medical Materials and Engineering, 2014, 24 (1), pp.S81-S88. ⟨10.3233/BME-140977⟩ Article dans une revue hal-01452704v1
Oxidative stress-induced expression of HSP70 contributes to the inhibitory effect of 15d-PGJ(2) on inducible prostaglandin pathway in chondrocytes Arnaud Bianchi,D. Moulin,S. Hupont,M. Koufany,P. Netteret al. Free Radical Biology and Medicine, 2014, 76, pp.114-126. ⟨10.1016/j.freeradbiomed.2014.07.028⟩ Article dans une revue hal-01453217v1
Association between adiponectin and cartilage degradation in human osteoarthritis P. -J. Francin,Anne Abot,Cécile Guillaume,David Moulin,Arnaud Bianchiet al. Osteoarthritis and Cartilage, 2014, 22 (3), pp.519-526. ⟨10.1016/j.joca.2014.01.002⟩ Article dans une revue hal-01452716v1
The Peroxisome Proliferator-Activated Receptor gamma Agonist Pioglitazone Preserves Bone Microarchitecture in Experimental Arthritis by Reducing the Interleukin-17-Dependent Osteoclastogenic Pathway Meriem Koufany,Daniel Chappard,Patrick Netter,Claire Bastien,Georges Weryhaet al. Arthritis and Rheumatism, 2013, 65 (12), pp.3084-3095. ⟨10.1002/art.38130⟩ Article dans une revue hal-01464666v1
Cytokines profiling by multiplex analysis in experimental arthritis: which pathophysiological relevance for articular versus systemic mediators? Joseph Paquet,Jean-Christophe Goebel,Camille Delaunay,Astrid Pinzano,Laurent Grossinet al. Arthritis Research and Therapy, 2012, 14 (2), pp.R60. ⟨10.1186/ar3774⟩ Article dans une revue hal-01715286v1
Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis Meriem Koufany,David Moulin,Arnaud Bianchi,Mikhaela Muresan,Sylvie Sébillaudet al. Arthritis Research and Therapy, 2008, 10 (1), pp.R6. ⟨10.1186/ar2354⟩ Article dans une revue hal-01715309v1
Evidence for species differences in the regulation of MMPs by all-trans retinoic acid in cytokine-stimulated chondrocytes. M. Kirchmeyer,J. Deffaud,S Sebillaud,David Moulin,Meriem Koufanyet al. Biorheology, 2008, 45 (3-4), pp.415-32 Article dans une revue hal-01715304v1
Pathophysiological relevance of peroxisome proliferators activated receptors (PPAR) to joint diseases – the pro and con of agonists Jean-Yves Jouzeau,David Moulin,Meriem Koufany,Sylvie Sébillaud,Arnaud Bianchiet al. Journal de la Société de Biologie, 2008, 202 (4), pp.289-312. ⟨10.1051/jbio:2008034⟩ Article dans une revue istex hal-01715298v1
Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells David Moulin,Olivier Donzé,Dominique Talabot-Ayer,Françoise Mezin,Gaby Palmeret al. Cytokine, 2007, 40 (3), pp.216-225. ⟨10.1016/j.cyto.2007.09.013⟩ Article dans une revue hal-01715320v1
Inorganic pyrophosphate generation by transforming growth factor-beta-1 is mainly dependent on ANK induction by Ras/Raf-1/extracellular signal-regulated kinase pathways in chondrocytes Frederic Cailotto,Arnaud Bianchi,Sylvie Sébillaud,Narayanan Venkatesan,David Moulinet al. Arthritis Research and Therapy, 2007, 9 (6), pp.R122. ⟨10.1186/ar2330⟩ Article dans une revue hal-01704426v1
Effect of peroxisome proliferator activated receptor (PPAR)gamma agonists on prostaglandins cascade in joint cells. David Moulin,Paul-Emile Poleni,Mélanie Kirchmeyer,Sylvie Sébillaud,Meriem Koufanyet al. Biorheology, 2006, 43, pp.561-75 Article dans une revue hal-01715321v1
Rosiglitazone induces interleukin-1 receptor antagonist in interleukin-1beta-stimulated rat synovial fibroblasts via a peroxisome proliferator-activated receptor beta/delta-dependent mechanism David Moulin,Arnaud Bianchi,Sandrine Boyault,Sylvie Sébillaud,Meriem Koufanyet al. Arthritis and Rheumatism, 2005, 52 (3), pp.759-769. ⟨10.1002/art.20868⟩ Article dans une revue hal-01715364v1
Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)γ agonists on membrane-associated prostaglandin E 2 synthase-1 in IL-1β-stimulated rat chondrocytes: evidence for PPARγ-independent inhibition by 15-deoxy-∆ 12,14 prostaglandin J 2 Arnaud Bianchi,David Moulin,Sylvie Sébillaud,Meriem Koufany,Marie-Madeleine Galteauet al. Arthritis Research and Therapy, 2005, 7 (6), pp.R1325-R1337. ⟨10.1186/ar1830⟩ Article dans une revue hal-01715324v1
Lack of genotoxicity of bitumen fumes in transgenic mouse lung. Jean Claude Micillino,Catherine Coulais,Stéphane Binet,Marie Claire Bottin,Gerard Keithet al. Toxicology, 2002, 170 (1-2), pp.11-20. ⟨10.1016/S0300-483X(01)00507-8⟩ Article dans une revue istex hal-01715374v1

Communication dans un congrès (7)

Screening of natural extract libraries for anti-inflammatory properties David Moulin,Sophie Rahuel-Clermont 2nd International Conference on Biomolecules and the Bioeconomy, Nov 2021, Nancy, France Communication dans un congrès hal-03516993v1
CSM de cordon ombilical : une thérapie cellulaire pour favoriser la prise de greffe de CSH sans majorer le risque de maladie du greffon contre l’hôte Cecile Pochon,Anne-Béatrice Notarantonio,Guillemette Fouquet,David Moulin,Naceur Charifet al. congrès de la SFGM-TC, Nov 2018, Montpellier, France Communication dans un congrès hal-03613798v1
Étude du microbiote intestinal et des cellules productrices d'IL-17 chez les souris arthritiques et lipo-atrophiques PPARγ déficientes : un modèle de désordre immunométabolique ? Julie Hablot,Jean-Yves Jouzeau,Meriem Koufany,Béatrice Desvergne,Gérard Eberlet al. 30ème Congrès Français de Rhumatologie (SFR), Dec 2017, Paris, France. pp.A139 (O.114) Communication dans un congrès hal-01775264v1
Pharmacological blockade of CCR3 improves collagen-induced arthritis J. Hablot,Meriem Koufany,Jean-Yves Jouzeau,David Moulin 20th Annual Meeting of French Society of Pharmacology and Therapeutics, 37th Pharmacovigilance Meeting, 17th APNET Seminar, 14th CHU CIC Meeting, Apr 2016, Nancy, France. pp.20-21, ⟨10.1111/fcp.12188⟩ Communication dans un congrès hal-01513896v1
FRI0017 Pharmacological Blockade of CCR3 Reduces Collagen-Induced Arthritis Severity J. Hablot,M. Koufany,P. Reboul,J.-Y. Jouzeau,D. Moulin Annual European Congress of Rheumatology (EULAR), 2016, Londres, United Kingdom. pp.431.3 - 432, ⟨10.1136/annrheumdis-2016-eular.4069⟩ Communication dans un congrès hal-01706984v1
Reciprocal influence of experimental arthritis on colitis: a model to study extraintestinal manifestations of IBD? Julie Hablot,Tunay Kökten,Jean-Yves Jouzeau,Harry Sokol,Laurent Peyrin-Birouletet al. 20ème congrès de la Société Française de Pharmacologie et de Thérapeutique (SFP&T), SFP&T, Apr 2016, NANCY, France. pp.75 (PS-123) Communication dans un congrès hal-03602064v1
PPAR gamma deficient mice develop spontaneous polyarthritis Meriem Koufany,F. Gilardi,M. Schiffrin,C. Winkler,Arnaud Bianchiet al. EULAR 2014, Jun 2014, Paris, France. pp.128 Communication dans un congrès hal-01514057v1

Poster de conférence (1)

Expression of HSP70 by oxidative stress contributes to the inhibitory effect of 15d-PGJ2 on inducible prostaglandin pathway in chondrocyte Arnaud Bianchi,David Moulin,Sebastien Hupont,Meriem Koufany,Patrick Netteret al. 10ème Congrès de la Société Française de Pharmacologie & Thérapeutique (SFP&T), Apr 2015, Caen, France. Fundamental and Clinical Pharmacology, 29 (Suppl 1), pp.31, 2015 Poster de conférence hal-01775312v1

Brevet (3)

Kynurenine aminotransferase and products thereof for the treatment of arthritic diseases Harry Sokol,David Moulin,Philippe Langella,Anne Aucouturier,Luis Bermúdez-Humarán France, Patent n° : WO2023247415A1. 2023 Brevet hal-05287276v1
Soluble trem-1 as a marker of severity or complications for a subject suffering from a coronovirus infection Jean-Jacques Garaud,Marc Derive,Margarita Salcedo-Magguilli,Lucie Jolly,Sebastien Gibotet al. France, Patent n° : 20305604.9-1118. 2020 Brevet hal-03005511v1
Antagonist of mineralocorticoid receptor for the treatment of osteoarthritis Anne Pizard,Chaohua Deng,Hervé Kempf,Arnaud Bianchi,David Moulinet al. France, Patent n° : WO2018019843. 2018 Brevet hal-02950844v1

Pré-publication, Document de travail (2)

Osteoclasts contribute to early development of chronic inflammation by promoting dysregulated hematopoiesis and myeloid skewing Maria-Bernadette Madel,Lidia Ibanez,Thomas Ciucci,Julia Halper,Majlinda Topiet al. 2021 Pré-publication, Document de travail hal-03064977v1
Adipose-tissue derived signals control bone remodelling He Fu,Maria-Bernadette Madel,Dominique Pierroz,Mariano Schiffrin,Carine Winkleret al. 2020 Pré-publication, Document de travail hal-02873939v1

Thèse (1)

Identification de cibles pharmacologiques des agonistes de PPAR gamma responsables de leurs potentialités anti-arthritiques David Moulin Biologie moléculaire. Université Henri Poincaré - Nancy 1, 2005. Français. ⟨NNT : 2005NAN11318⟩ Thèse tel-01746982v1

HDR (1)

« Étude des relations entre Immunité et Métabolisme dans les maladies inflammatoires chroniques » David Moulin Sciences du Vivant [q-bio]. Université de Lorraine, 2023 HDR tel-04196097v1