Davy SINNAEVE

Publications

Article dans une revue (25)

Fast Ultra‐Selective 1H‐15N 1D NMR Spectroscopy Unlocks Atom‐Resolved Dynamics of Low‐Complexity Protein Regions Wiktor Adamski,Geraldine R Levy,François-Xavier Cantrelle,Davy Sinnaeve Angewandte Chemie International Edition, 2026, pp.e19206. ⟨10.1002/anie.202519206⟩ Article dans une revue hal-05534270v1
Site-Specific Incorporation of Fluorinated Prolines into Proteins and their Impact on Neighbouring Residues Carlos Elena-Real,Annika Urbanek,Amin Sagar,Priyesh Mohanty,Geraldine Levyet al. Chemistry - A European Journal, In press, ⟨10.1002/chem.202403718⟩ Article dans une revue hal-04865645v1
Making 1H– 1H Couplings More Accessible and Accurate with Selective 2DJ NMR Experiments Aided by 13C Satellites François-Xavier Cantrelle,Emmanuelle Boll,Davy Sinnaeve Analytical Chemistry, 2024, 96 (18), pp.7056-7064. ⟨10.1021/acs.analchem.4c00315⟩ Article dans une revue hal-04733955v1
Conformation and Affinity Modulations by Multiple Phosphorylation Occurring in the BIN1 SH3 Domain Binding Site of the Tau Protein Proline-Rich Region Alessia Lasorsa,Krishnendu Bera,Idir Malki,Elian Dupré,François-Xavier Cantrelleet al. Biochemistry, 2023, 62 (11), pp.1631-1642. ⟨10.1021/acs.biochem.2c00717⟩ Article dans une revue hal-04140342v1
Obtaining Pure 1H NMR Spectra of Individual Pyranose and Furanose Anomers of Reducing Deoxyfluorinated Sugars Gabija Poškaitė,David E Wheatley,Neil Wells,Bruno Linclau,Davy Sinnaeve Journal of Organic Chemistry, 2023, 88 (19), pp.13908 - 13925. ⟨10.1021/acs.joc.3c01503⟩ Article dans une revue hal-04304362v1
The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity Carlos A Elena-Real,Amin Sagar,Annika Urbanek,Matija Popovic,Anna Moratóet al. Nature Structural and Molecular Biology, 2023, 30 (3), pp.309 - 320. ⟨10.1038/s41594-023-00920-0⟩ Article dans une revue hal-04052774v1
Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools Isabelle Landrieu,Elian Dupré,Davy Sinnaeve,Léa El Hajjar,Caroline Smet-Nocca Frontiers in Chemistry, 2022, 10, pp.886382. ⟨10.3389/fchem.2022.886382⟩ Article dans une revue hal-03841022v1
Relating Conformational Equilibria to Conformer‐Specific Lipophilicities: New Opportunities in Drug Discovery Bruno Linclau,Zhong Wang,Benjamin Jeffries,Jérôme Graton,Rodrigo Carbajoet al. Angewandte Chemie International Edition, 2022, 61 (7), pp.e202114862. ⟨10.1002/anie.202114862⟩ Article dans une revue hal-03635530v1
Fluorine NMR study of proline-rich sequences using fluoroprolines Davy Sinnaeve,Abir Ben Bouzayene,Emile Ottoy,Gert-Jan Hofman,Eva Erdmannet al. Magnetic Resonance, 2021, 2 (2), pp.795-813. ⟨10.5194/mr-2-795-2021⟩ Article dans une revue hal-03430871v1
Expedited NMR Assignment of Small- to Medium-Sized Molecules with Improved HSQC−CLIP−COSY Experiments Tamás Gyöngyösi,István Timári,Davy Sinnaeve,Burkhard Luy,Katalin E. Kövér Analytical Chemistry, 2021, 93 (6), pp.3096-3102. ⟨10.1021/acs.analchem.0c04124⟩ Article dans une revue hal-03328594v1
Probing Long‐Range Anisotropic Interactions: a General and Sign‐Sensitive Strategy to Measure 1 H– 1 H Residual Dipolar Couplings as a Key Advance for Organic Structure Determination Davy Sinnaeve,Julian Ilgen,Maria Enrica Di Pietro,Johann Primozic,Volker Schmidtset al. Angewandte Chemie International Edition, 2020, 59 (13), pp.5316-5320. ⟨10.1002/anie.201915278⟩ Article dans une revue hal-02538220v1
Identification of the Molecular Determinants Involved in Antimicrobial Activity of Pseudodesmin A, a Cyclic Lipopeptide From the Viscosin Group Matthias de Vleeschouwer,Tim van Kersavond,Yentl Verleysen,Davy Sinnaeve,Tom Coenyeet al. Frontiers in Microbiology, 2020, 11, pp.646. ⟨10.3389/fmicb.2020.00646⟩ Article dans une revue hal-03007409v1
Targeted delivery of adamantylated peptidoglycan immunomodulators in lipid nanocarriers: NMR shows that cargo fragments are available on the surface Rosana Ribić,Mateja Manček-Keber,Fernando Chain,Davy Sinnaeve,José C Martinset al. Journal of Physical Chemistry B, 2020, 124 (20), pp.4132-4145. ⟨10.1021/acs.jpcb.0c00029⟩ Article dans une revue hal-03009687v1
1H, 13C, and 15N chemical shift assignment of human PACSIN1/syndapin I SH3 domain in solution Emmanuelle Boll,François-Xavier Cantrelle,Isabelle Landrieu,Matthieu Hirel,Davy Sinnaeveet al. Biomolecular NMR Assignments, 2020, ⟨10.1007/s12104-020-09940-z⟩ Article dans une revue hal-02537946v1
Selective homonuclear 2D J-resolved spectroscopy Davy Sinnaeve eMagRes, 2020, 9 (4), pp.267-282. ⟨10.1002/9780470034590.emrstm1544⟩ Article dans une revue hal-03322837v1
Adamantane Containing Peptidoglycan Fragments Enhance RANTES and IL-6 Production in Lipopolysaccharide-Induced Macrophages Mateja Manček-Keber,Rosana Ribić,Fernando Chain,Davy Sinnaeve,José C. Martinset al. Molecules, 2020, 25 (16), pp.3707. ⟨10.3390/molecules25163707⟩ Article dans une revue hal-03008032v1
Conformation and Dynamics of the Cyclic Lipopeptide Viscosinamide at the Water-Lipid Interface Niels Geudens,Benjamin Kovács,Davy Sinnaeve,Feyisara Eyiwumi Oni,Monica Höfteet al. Molecules, 2019, 24 (12), pp.2257. ⟨10.3390/molecules24122257⟩ Article dans une revue hal-02538368v1
Fluorescent Pseudomonas and cyclic lipopeptide diversity in the rhizosphere of cocoyam ( Xanthosoma sagittifolium ) Feyisara Eyiwumi Oni,Niels Geudens,Olumide Owolabi Omoboye,Lien Bertier,Hoang Gia Khuong Huaet al. Environmental Microbiology, 2019, 21 (3), pp.1019-1034. ⟨10.1111/1462-2920.14520⟩ Article dans une revue hal-02538659v1
Quantification of the electrostatic and covalent interaction between whey proteins and low methoxyl pectin using PFG-NMR diffusometry Arima Diah Setiowati,Lien Vermeir,Lorenz de Neve,Ali Sedaghat Doost,Davy Sinnaeveet al. Magnetic Resonance in Chemistry, 2019, Latest Developments and Applications of magnetic resonance in food science, 57 (9), pp.719-729. ⟨10.1002/mrc.4812⟩ Article dans une revue hal-02538690v1
Molecular Model for the Self-Assembly of the Cyclic Lipodepsipeptide Pseudodesmin A Jean-Marc Crowet,Davy Sinnaeve,Krisztina Fehér,Yoann Laurin,Magali Deleuet al. Journal of Physical Chemistry B, 2019, 123 (42), pp.8916-8922. ⟨10.1021/acs.jpcb.9b08035⟩ Article dans une revue hal-02538325v1
Synthesis and Conformational Properties of 3,4-Difluoro- l -prolines Gert-Jan Hofman,Emile Ottoy,Mark E. Light,Bruno Kieffer,José C. Martinset al. Journal of Organic Chemistry, 2019, 84 (6), pp.3100-3120. ⟨10.1021/acs.joc.8b02920⟩ Article dans une revue hal-02538639v1
Improved Isotopic Profiling by Pure Shift Heteronuclear 2D J -Resolved NMR Spectroscopy Davy Sinnaeve,Mickael Dinclaux,Edern Cahoreau,Pierre Millard,Jean-Charles Portaiset al. Analytical Chemistry, 2018, 90 (6), pp.4025-4031. ⟨10.1021/acs.analchem.7b05206⟩ Article dans une revue hal-02131883v1
Minimising conformational bias in fluoroprolines through vicinal difluorination Gert-Jan Hofman,Emile Ottoy,Mark Light,Bruno Kieffer,Ilya Kuprovet al. Chemical Communications, 2018, 54 (40), pp.5118-5121. ⟨10.1039/c8cc01493k⟩ Article dans une revue hal-03671903v1
Insight into peptide self-assembly from anisotropic rotational diffusion derived from 13C NMR relaxation Davy Sinnaeve,Marc-André Delsuc,José Martins,Bruno Kieffer Chemical Science, 2012, 3 (4), pp.1284. ⟨10.1039/C2SC01088G⟩ Article dans une revue hal-04984218v1
Intermolecular interaction studies using small volumes. David Bourry,Davy Sinnaeve,Katelijne Gheysen,Bernd Fritzinger,Gianni Vandenborreet al. Magnetic Resonance in Chemistry, 2011, 49 (1), pp.9-15. ⟨10.1002/mrc.2699⟩ Article dans une revue istex hal-00586937v1

Pré-publication, Document de travail (3)

Fast ultra-selective 1H-15N 1D NMR spectroscopy unlocks atom-resolved dynamics of low-complexity protein regions Wiktor Adamski,Géraldine Levy,François-Xavier Cantrelle,Davy Sinnaeve 2025 Pré-publication, Document de travail hal-05393364v1
Making 1H-1H couplings more accessible and accurate with selective 2DJ NMR experiments aided by 13C satellites François-Xavier Cantrelle,Emmanuelle Boll,Davy Sinnaeve 2024 Pré-publication, Document de travail hal-04438247v1
The structure of pathogenic huntingtin exon-1 defines the bases of its aggregation propensity Carlos A Elena-Real,Amin Sagar,Annika Urbanek,Matija Popovic,Anna Moratóet al. 2022 Pré-publication, Document de travail hal-03846359v1

Poster de conférence (9)

A library of fluorinated prolines to study proline−rich motifs with 19F NMR Emile Ottoy,Bruno Linclau,Bruno Kieffer,Ilya Kuprov,Davy Sinnaeve Noncanonical amino acids (ncAAs): Tools for Biological and Biophysical Investigations, 2nd edition meeting, Oct 2024, Paris, France Poster de conférence hal-05017059v1
Conformational ensemble analysis of flexible peptides using residual dipolar couplings Elisa Norzagaray,Wiktor Adamski,Davy Sinnaeve 20th edition of the Young Belgian Magnetic Resonance Scientists symposium - YBMRS 2024, Nov 2024, Blankenberge, Belgium Poster de conférence hal-05017160v1
A library of fluorinated prolines to study proline-rich motifs with 19F NMR Emile Ottoy,Bruno Linclau,Bruno Kieffer,Ilya Kuprov,Davy Sinnaeve The 20th European Magnetic Resonance Congress (EUROMAR 2024), Jun 2024, Bilbao, Spain Poster de conférence hal-05017022v1
Applications of real-time band-selective pure shift in 1H-15N HSQC experiments for 15N-labelled proteins Jorge Moreira,Alexander P. Golovanov,Gareth A Morris,Mathias J Nilsson,Peter Kiralyet al. The 20th European Magnetic Resonance Congress (EUROMAR 2024), Jun 2024, Bilbao, Spain Poster de conférence hal-05017134v1
Fast access to protein dynamics using Hartmann-Hahn edited 15N- 1H spectroscopy Wiktor Adamski,François-Xavier Cantrelle,Davy Sinnaeve The 20th European Magnetic Resonance Congress (EUROMAR 2024), Jun 2024, Bilbao, Spain Poster de conférence hal-05017142v1
Molecular Dynamics with Orientational Constraints to investigate the conformational landscape of biomolecules Wiktor Adamski,Xavier Hanoulle,Davy Sinnaeve XIIIth International Conference — NMR: a tool for biology, May 2023, Paris, France Poster de conférence hal-05017701v1
Molecular Dynamics with Orientational Constraints to investigate the conformational landscape of biomolecules Wiktor Adamski,Xavier Hanoulle,Davy Sinnaeve The 19th European Magnetic Resonance Congress (EUROMAR 2023), Jul 2023, Glasgow, United Kingdom Poster de conférence hal-05017117v1
A general method for fully homodecoupled 1H-13C HSQC spectra James R. D. Montgomery,Davy Sinnaeve The 18th European Magnetic Resonance Congress (EUROMAR 2022), Jul 2022, Utrecht, Netherlands Poster de conférence hal-05016941v1
A general method for fully homodecoupled 1H-13C HSQC spectra Davy Sinnaeve The 1st Virtual Conference of the GERM, Apr 2021, En ligne, France Poster de conférence hal-05016934v1

Communication dans un congrès (8)

Improved measurement and suppression of 1H−1H couplings aided by 13C nuclei Davy Sinnaeve 12èmes Rencontres RMN-RPE-IRM, Le pôle RMN de l’Université de Lille, Jun 2024, Lille, France Communication dans un congrès hal-05016882v1
A library of fluorinated prolines to study proline−rich motifs with 19F NMR Davy Sinnaeve,Emile Ottoy,Bruno Linclau,Bruno Kieffer,Ilya Kuprov Advanced Isotopic Labelling Methods for Integrated Structural Biology 2024, May 2024, Grenoble, France Communication dans un congrès hal-05016924v1
Fast access to protein dynamics using ultra-selective 15N-1H spectroscopy Wiktor Adamski,François-Xavier Cantrelle,Géraldine Levy,Davy Sinnaeve 20th edition of the Young Belgian Magnetic Resonance Scientists symposium - YBMRS 2024, Nov 2024, Blankenberge, Belgium Communication dans un congrès hal-05017163v1
Improving accuracy and accessibility in ¹H-¹H coupling measurements by using ¹³C satellites Davy Sinnaeve The 19th European Magnetic Resonance Congress (EUROMAR 2023), Groupement Ampere, Jul 2023, Glasgow, United Kingdom Communication dans un congrès hal-05016844v1
Conformational dynamics analysis of (macro)molecules from Residual Dipolar Couplings and Heteronuclear Spin Relaxation Wiktor Adamski,Davy Sinnaeve 11es Rencontres RMN-RPE (Lille), Le pôle RMN de l’Université de Lille, Nov 2023, Villeneuve d'Ascq, France Communication dans un congrès hal-05017167v1
Making good use of 13C to either measure or suppress 1H-1H couplings Davy Sinnaeve Réunion RMN Grand Bassin Parisien, Réseau RMN structurale dans le Bassin Parisien; Fr2950 CNRS Fédération RMN Solide Hauts Champs, Jan 2023, Paris, France Communication dans un congrès hal-05016793v1
Premier spectromètre RMN 1,2 GHz français : quelles nouvelles possibilités pour l’analyse ? Fabien Ferrage,Pierre Florian,Guy Lippens,Emmanuel Maes,Guido Pintacudaet al. Réunion des utilisateurs RMN de Bruker France, Nov 2023, Lille, France Communication dans un congrès hal-04470791v1
New ways to measure and suppress 1H-1H couplings in 1H-13C experiments Davy Sinnaeve 43rd FGMR Annual Discussion Meeting, Division of Magnetic Resonance of the German Chemical society, Sep 2022, Karlsruhe, Germany Communication dans un congrès hal-05016769v1