Déborah HELLE

Publications

Article dans une revue (15)

B3GALT6 mutations lead to compromised connective tissue biomechanics in Ehlers-Danlos syndrome Roméo Milan Diana,Benjamin Jolivet,Jean-Baptiste Vincourt,Sébastien Hergalant,Grégory Franciuset al. JCI Insight, 2025, 10 (16), pp.e179474. ⟨10.1172/jci.insight.179474⟩ Article dans une revue hal-05234907v1
MicroRNAs miR-16 and miR-519 control meningioma cell proliferation via overlapping transcriptomic programs shared with the RNA-binding protein HuR Sébastien Hergalant,Jean-Matthieu Casse,Abderrahim Oussalah,Rémi Houlgatte,Deborah Helleet al. Frontiers in Oncology, 2023, 13, pp.1158773. ⟨10.3389/fonc.2023.1158773⟩ Article dans une revue hal-04176105v1
Characterization of an Innovative Biomaterial Derived From Human Wharton’s Jelly as a New Promising Coating for Tissue Engineering Applications Adrien Fayon,Deborah Helle,Gregory Francius,Jean-Baptiste Vincourt,Véronique Regnaultet al. Frontiers in Bioengineering and Biotechnology, 2022, 10, pp.884069. ⟨10.3389/fbioe.2022.884069⟩ Article dans une revue hal-03753092v1
Glucocorticoid Receptor Activation Restores Learning Memory by Modulating Hippocampal Plasticity in a Mouse Model of Brain Vitamin B12 Deficiency Natacha Dreumont,Khalid Mimoun,Carine Pourié,Edward Quadros,Jean-Marc Albertoet al. Molecular Neurobiology, 2020, 58 (3), pp.1024-1035. ⟨10.1007/s12035-020-02163-2⟩ Article dans une revue hal-03043614v1
Methyl Donor Deficiency during Gestation and Lactation in the Rat Affects the Expression of Neuropeptides and Related Receptors in the Hypothalamus L Saber Cherif,P Pourié,A Geoffroy,A Julien,Deborah Helleet al. International Journal of Molecular Sciences, 2019, 20 (20), pp.5097. ⟨10.3390/ijms20205097⟩ Article dans une revue hal-03049896v1
N‐homocysteinylation of tau and MAP1 is increased in autopsy specimens of Alzheimer's disease and vascular dementia Carine Bossenmeyer-Pourie,David A. Smith,Sylvain Lehmann,Vincent Deramecourt,Bernard Sablonnièreet al. Journal of Pathology, 2019, 248 (3), pp.291-303. ⟨10.1002/path.5254⟩ Article dans une revue hal-02389312v1
Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid Andréa Geoffroy,Lynda Saber-Cherif,Grégory Pourié,Deborah Helle,Rémy Umoretet al. International Journal of Molecular Sciences, 2019, 20 (4), pp.973. ⟨10.3390/ijms20040973⟩ Article dans une revue hal-03049898v1
Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia Guillaume Gauchotte,Sébastien Hergalant,Charlène Vigouroux,Matthieu Casse,Rémi Houlgatteet al. The Journal of pathology and bacteriology, 2017, 242 (4), pp.421 - 434. ⟨10.1002/path.4916⟩ Article dans une revue hal-01718786v1
Late Maternal Folate Supplementation Rescues from Methyl Donor Deficiency-Associated Brain Defects by Restoring Let-7 and miR-34 Pathways Andrea Geoffroy,Racha Kerek,Grégory Pourié,Deborah Helle,Jean-Louis Guéantet al. Molecular Neurobiology, 2017, 54 (7), pp.5017-5033. ⟨10.1007/s12035-016-0035-8⟩ Article dans une revue hal-01666792v1
Methyl donor deficiency impairs bone development via peroxisome proliferator-activated receptor- coactivator-1 -dependent vitamin D receptor pathway E. Feigerlova,L. Demarquet,H. Melhem,R. Ghemrawi,S.-F. Battaglia-Hsuet al. FASEB Journal, 2016, 30 (10), pp.3598 - 3612. ⟨10.1096/fj.201600332R⟩ Article dans une revue hal-01666802v1
Folate- and vitamin B-12-deficient diet during gestation and lactation alters cerebellar synapsin expression via impaired influence of estrogen nuclear receptor alpha Grégory Pourié,Nicolas Martin,Carine Bossenmeyer-Pourie,Nassila Akchiche,Rosa Maria Gueant-Rodriguezet al. FASEB Journal, 2015, 29 (9), pp.3713-3725. ⟨10.1096/fj.14-264267⟩ Article dans une revue hal-01217630v1
Early methyl donor deficiency may induce persistent brain defects by reducing Stat3 signaling targeted by miR-124 R Kerek,G. Geoffroy,A Bison,N Martin,N Akchicheet al. Cell Death and Disease, 2013, 4 (8), pp.e755 - e755. ⟨10.1038/cddis.2013.278⟩ Article dans une revue hal-01701266v1
Early methyl donor deficiency produces severe gastritis in mothers and offspring through N -homocysteinylation of cytoskeleton proteins, cellular stress, and inflammation Carine Bossenmeyer-Pourié,Grégory Pourié,Violette Koziel,Deborah Helle,Elise Jeannessonet al. FASEB Journal, 2013, 27 (6), pp.2185 - 2197. ⟨10.1096/fj.12-224642⟩ Article dans une revue hal-01701775v1
Su1754 Persistence of the Gastric Mucosa Inflammation After Fetal and Early Post-Natal Exposition to Methyl Donor Deficiency in the Rat Carine Pourie,Jean-Luc Daval,Grégory Pourié,Catherine Tomasetto,Déborah Helleet al. Gastroenterology, 2012, 142 (5), pp.S-495 - S-496. ⟨10.1016/S0016-5085(12)61896-4⟩ Article dans une revue hal-01718806v1
Homocysteinylation of neuronal proteins contributes to folate deficiency-associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal cells. Nassila Akchiche,Carine Bossenmeyer-Pourié,Racha Kerek,Nicolas Martin,Grégory Pouriéet al. FASEB Journal, 2012, 26 (10), pp.3980-92. ⟨10.1096/fj.12-205757⟩ Article dans une revue hal-00759122v1

Communication dans un congrès (3)

Harvesting extracellular matrix of wharton's jelly by extraction or decellularization process: a promising material for cardiovascular tissue engineering Nathan Wisniewski,Reine El Omar,Deborah Helle,Caroline Gaucher Biomat-MatSan 2024, Association française pour le développement des biomatériaux; Comission mixte MatSan (Matériaux pour la Santé), Jan 2024, Super Besse, France Communication dans un congrès hal-04587186v1
Harvesting the Wharton’s Jelly Extracellular matrix using an ultrasound assisted Acetic Acid protocol to produce a material suitable for cardiovascular tissue engineering Nathan Wisniewski,Reine El Omar,Alexandra Kleinclauss,Gregory Francius,Deborah Helleet al. International Conference on Biomaterials and Biofabrication 2024, May 2024, Nancy, France Communication dans un congrès hal-04587207v1
Human umbilical cord: All what we need for an ideal tissue-engineered vascular graft Reine El Omar,P Dan,Deborah Helle,Veronique Decot,Patrick Menu ISACB, Sep 2018, Bordeaux, France Communication dans un congrès hal-02883644v1

Poster de conférence (2)

Therapeutic evaluation of a tissue-engineered vascular graft build from human umbilical cord: scaffold improvement and in vivo evaluation Adrien Fayon,Deborah Helle,Patrick Menu,Reine El Omar Engineering small vessels and micro-vascularization for 3D models and regenerative medicine, Dec 2019, Paris, France Poster de conférence hal-03642335v1
Human umbilical cord: all what we need for an ideal vascular graft Reine El Omar,Pan Dan,Deborah Helle,Veronique Decot,Patrick Menu ISACB 2018, Sep 2018, Bordeaux, France Poster de conférence hal-03642337v1