Delphine SAPALY

Identifiants chercheurs

IdHAL :

delphine-sapaly

ORCID :

0000-0003-1112-2495

Publications

Article dans une revue (10)

Combining SMN2 splicing modifiers with HDAC6 inhibition greatly improves muscle function and survival in Spinal Muscular Atrophy Alexis Osseni,Rasha Slika,Laurent Coudert,Agnes Conjard-Duplany,Laure Weillet al. BioRxiv, 2025, ⟨10.1101/2025.01.15.633267⟩ Article dans une revue hal-05044738v1
Drug Candidate BIO101 for Spinal Muscular Atrophy as Monotherapy or Combined With the Antisense Oligonucleotide ASO‐10‐27 Cynthia Bézier,Steve Cottin,Parvin Nazari Hashemi,Mirella El Khoury,Zoé Clercet al. Journal of Cachexia, Sarcopenia and Muscle, 2025, 16 (5), pp.e70104. ⟨10.1002/jcsm.70104⟩ Article dans une revue hal-05453886v1
The analysis of the skeletal muscle metabolism is crucial for designing optimal exercise paradigms in type 2 diabetes mellitus Elias Abi Akar,Laure Weill,Mirella El Khoury,Cédric Caradeuc,Gildas Berthoet al. Molecular Medicine, 2024, 30 (1), pp.80. ⟨10.1186/s10020-024-00850-7⟩ Article dans une revue hal-05316643v1
Understanding the Role of the SMN Complex Component GEMIN5 and Its Functional Relationship with Demethylase KDM6B in the Flunarizine-Mediated Neuroprotection of Motor Neuron Disease Spinal Muscular Atrophy Badih Salman,Emeline Bon,Perrine Delers,Steve Cottin,Elena Pashoet al. International Journal of Molecular Sciences, 2024, 25 (18), pp.10039. ⟨10.3390/ijms251810039⟩ Article dans une revue hal-05453872v1
Dysregulation of muscle cholesterol transport in amyotrophic lateral sclerosis D. Sapaly,F. Cheguillaume,L. Weill,Z. Clerc,O. Biondiet al. Brain - A Journal of Neurology , 2024, Brain, 148 (3), p.788-802. ⟨10.1093/brain/awae270⟩ Article dans une revue hal-04977711v1
NADPH oxidase 4 inhibition is a complementary therapeutic strategy for spinal muscular atrophy Mirella El Khoury,Olivier Biondi,Gaelle Bruneteau,Delphine Sapaly,Sabrina Bendriset al. Frontiers in Cellular Neuroscience, 2023, 17, ⟨10.3389/fncel.2023.1242828⟩ Article dans une revue hal-04495927v1
Activating ATF6 in spinal muscular atrophy promotes SMN expression and motor neuron survival through the IRE1α‐XBP1 pathway Domenico d'Amico,Olivier Biondi,Camille Januel,Cynthia Bezier,Delphine Sapalyet al. Neuropathology and Applied Neurobiology, 2022, 48 (5), pp.e12816. ⟨10.1111/nan.12816⟩ Article dans une revue inserm-04385529v1
The Small-Molecule Flunarizine in Spinal Muscular Atrophy Patient Fibroblasts Impacts on the Gemin Components of the SMN Complex and TDP43, an RNA-Binding Protein Relevant to Motor Neuron Diseases Delphine Sapaly,Perrine Delers,Jennifer Coridon,Badih Salman,Franck Letourneuret al. Frontiers in Molecular Biosciences, 2020, 7, pp.55. ⟨10.3389/fmolb.2020.00055⟩ Article dans une revue hal-05453823v1
Low-Intensity Running and High-Intensity Swimming Exercises Differentially Improve Energy Metabolism in Mice With Mild Spinal Muscular Atrophy Léo Houdebine,Domenico d'Amico,Jean Bastin,Farah Chali,Céline Desseilleet al. Frontiers in Physiology, 2019, 10, pp.1258. ⟨10.3389/fphys.2019.01258⟩ Article dans une revue inserm-02893893v1
Small-molecule flunarizine increases SMN protein in nuclear Cajal bodies and motor function in a mouse model of spinal muscular atrophy Delphine Sapaly,Matthieu Dos Santos,Perrine Delers,Olivier Biondi,Gwendoline Quérolet al. Scientific Reports, 2018, 8 (1), pp.2075. ⟨10.1038/s41598-018-20219-1⟩ Article dans une revue pasteur-02090360v1