Dimitra Gkika

Publications

Article dans une revue (47)

Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to-mesenchymal transition. Mathilde Lebas,Giorgia Chinigò,Evan Courmont,Louay Bettaieb,Amani Machmouchiet al. Science Advances , 2024, Sci Adv, 10 (32), eadp6182. ⟨10.1126/sciadv.adp6182⟩ Article dans une revue hal-04711617v1
Editorial: From mechanosensing to signalling and cell response: The ion channel force Dimitra Gkika,Albrecht Schwab Frontiers in Cell and Developmental Biology, 2023, 11, ⟨10.3389/fcell.2023.1183726⟩ Article dans une revue hal-04361631v1
TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance? Mayar Soussi,Alice Hasselsweiller,Dimitra Gkika Membranes, 2023, 13 (9), pp.788. ⟨10.3390/membranes13090788⟩ Article dans une revue (article de synthèse) hal-04361627v1
TRPM8 as an Anti–Tumoral Target in Prostate Cancer Growth and Metastasis Dissemination Guillaume Grolez,Giorgia Chinigò,Alexandre Barras,Mehdi Hammadi,Lucile Noyeret al. International Journal of Molecular Sciences, 2022, Calcium Signaling in Human Health and Diseases 3.0, 23 (12), pp.6672. ⟨10.3390/ijms23126672⟩ Article dans une revue hal-03746647v1
TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells Giorgia Chinigò,Guillaume Grolez,Madelaine Audero,Alexandre Bokhobza,Michela Bernardiniet al. Cancers, 2022, 14 (9), pp.2261. ⟨10.3390/cancers14092261⟩ Article dans une revue hal-03842400v1
TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence Valerio Farfariello,Dmitri Gordienko,Lina Mesilmany,Yasmine Touil,Emmanuelle Germainet al. Nature Communications, 2022, 13 (1), pp.956. ⟨10.1038/s41467-022-28597-x⟩ Article dans une revue hal-03666578v1
TRP Channels in Brain Tumors Giorgia Chinigò,Hélène Castel,Oana Chever,Dimitra Gkika Frontiers in Cell and Developmental Biology, 2021, 9 (617801), pp.1-17. ⟨10.3389/fcell.2021.617801⟩ Article dans une revue hal-04503098v1
Ion Channel Profiling in Prostate Cancer: Toward Cell Population-Specific Screening Valerio Farfariello,Natalia Prevarskaya,Dimitra Gkika Reviews of Physiology Biochemistry and Pharmacology, 2020, Reviews of Physiology, Biochemistry and Pharmacology, 181, pp.39-56. ⟨10.1007/112_2020_22⟩ Article dans une revue hal-04503116v1
The Two-Way Relationship Between Calcium and Metabolism in Cancer Camille Dejos,Dimitra Gkika,Anna Rita Cantelmo Frontiers in Cell and Developmental Biology, 2020, 8, pp.573747. ⟨10.3389/fcell.2020.573747⟩ Article dans une revue hal-04503102v1
TRP Channels and Small GTPases Interplay in the Main Hallmarks of Metastatic Cancer Giorgia Chinigò,Alessandra Fiorio Pla,Dimitra Gkika Frontiers in Pharmacology, 2020, 11 (581455), pp.1-16. ⟨10.3389/fphar.2020.581455⟩ Article dans une revue hal-04503106v1
Testosterone‐androgen receptor: The steroid link inhibiting TRPM8‐mediated cold sensitivity Dimitra Gkika,Stéphane Lolignier,Guillaume Grolez,Alexis Bavencoffe,Georges Shapovalovet al. FASEB Journal, 2020, 34 (6), pp.7483-7499. ⟨10.1096/fj.201902270R⟩ Article dans une revue hal-03512394v1
Ca&lt;sup&gt;2+&lt;/sup&gt; Channel Toolkit in Neuroendocrine Tumors Alessandra Fiorio Pla,Dimitra Gkika Neuroendocrinology, 2020, 110 (1-2), pp.147-154. ⟨10.1159/000501397⟩ Article dans une revue hal-04503120v1
Partners in Crime: Towards New Ways of Targeting Calcium Channels Lucile Noyer,Loic Lemonnier,Pascal Mariot,Dimitra Gkika International Journal of Molecular Sciences, 2019, 20 (24), pp.6344. ⟨10.3390/ijms20246344⟩ Article dans une revue (article de synthèse) hal-04210077v1
Partners in Crime: Towards New Ways of Targeting Calcium Channels Lucile Noyer,Loic Lemonnier,Pascal Mariot,Dimitra Gkika International Journal of Molecular Sciences, 2019, 20 (24), pp.6344. ⟨10.3390/ijms20246344⟩ Article dans une revue hal-04318506v1
TRPM8-androgen receptor association within lipid rafts promotes prostate cancer cell migration Guillaume P. Grolez,Dmitri V. Gordiendko,Manon Clarisse,Mehdi Hammadi,Emilie Desruelleset al. Cell Death and Disease, 2019, 10 (9), pp.652. ⟨10.1038/s41419-019-1891-8⟩ Article dans une revue hal-03133861v1
Transient Receptor Potential Channel Expression Signatures in Tumor-Derived Endothelial Cells: Functional Roles in Prostate Cancer Angiogenesis Michela Bernardini,Alessia Brossa,Giorgia Chinigo,Guillaume Grolez,Giulia Trimaglioet al. Cancers, 2019, 11 (7), pp.956. ⟨10.3390/cancers11070956⟩ Article dans une revue hal-02404061v1
TRPV1 variants impair intracellular Ca2+ signaling and may confer susceptibility to malignant hyperthermia Fabien Vanden Abeele,Sabine Lotteau,Sylvie Ducreux,Charlotte Dubois,Nicole Monnieret al. Genetics in Medicine, 2019, 21 (2), pp.441-450. ⟨10.1038/s41436-018-0066-9⟩ Article dans une revue hal-02475163v1
Dual contribution of TRPV4 antagonism in the regulatory effect of vasoinhibins on blood-retinal barrier permeability: diabetic milieu makes a difference David Arredondo Zamarripa,Ramsés Noguez Imm,Ana María Bautista Cortés,Osvaldo Vázquez Ruíz,Michela Bernardiniet al. Scientific Reports, 2017, 7 (1), pp.13094. ⟨10.1038/s41598-017-13621-8⟩ Article dans une revue hal-04038979v1
TRPM8 Puts the Chill on Prostate Cancer Guillaume P. Grolez,Dimitra Gkika Pharmaceuticals, 2016, 9 (3), pp.44. ⟨10.3390/ph9030044⟩ Article dans une revue hal-04503126v1
New Insight in Cold Pain: Role of Ion Channels, Modulation, and Clinical Perspectives Stéphane Lolignier,Dimitra Gkika,David Andersson,Enrico Leipold,Irina Vetteret al. Journal of Neuroscience, 2016, 36 (45), pp.11435 - 11439. ⟨10.1523/jneurosci.2327-16.2016⟩ Article dans une revue hal-03512571v1
Human transient receptor potential (TRP) channel expression profiling in carcinogenesis Michela Bernardini,Alessandra Fiorio Pla,Natalia Prevarskaya,Dimitra Gkika International Journal of Developmental Biology, 2015, 59 (7-8-9), pp.399-406. ⟨10.1387/ijdb.150232dg⟩ Article dans une revue hal-04039012v1
TRP channel–associated factors are a novel protein family that regulates TRPM8 trafficking and activity Dimitra Gkika,Loic Lemonnier,George Shapovalov,Dmitri Gordienko,Céline Pouxet al. Journal of Cell Biology, 2015, 208 (1), pp.89-107. ⟨10.1083/jcb.201402076⟩ Article dans une revue hal-01111024v1
Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib Alessandra Fiorio Pla,Alessia Brossa,Michela Bernardini,Tullio Genova,Guillaume Grolezet al. BMC Cancer, 2014, 14 (1), pp.939. ⟨10.1186/1471-2407-14-939⟩ Article dans une revue hal-04039024v1
Remodeling of Channel-Forming ORAI Proteins Determines an Oncogenic Switch in Prostate Cancer Charlotte Dubois,Fabien Vanden Abeele,V’yacheslav Lehen’kyi,Dimitra Gkika,Basma Guarmitet al. Cancer Cell, 2014, 26 (1), pp.19-32. ⟨10.1016/j.ccr.2014.04.025⟩ Article dans une revue hal-04039033v1
Complex modulation of the cold receptor TRPM8 by volatile anaesthetics and its role in complications of general anaesthesia Fabien Vanden Abeele,Artem Kondratskyi,Charlotte Dubois,George Shapovalov,Dimitra Gkikaet al. Journal of Cell Science, 2013, 126 (19), pp.4479-4489. ⟨10.1242/jcs.131631⟩ Article dans une revue hal-04039037v1
TRPV2 Mediates Adrenomedullin Stimulation of Prostate and Urothelial Cancer Cell Adhesion, Migration and Invasion Agathe Oulidi,Alexandre Bokhobza,Dimitra Gkika,Fabien Vanden Abeele,V’yacheslav Lehen’kyiet al. PLoS ONE, 2013, 8 (5), pp.e64885. ⟨10.1371/journal.pone.0064885⟩ Article dans une revue hal-04039050v1
Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib. Alessandra Fiorio Pla,Alessia Brossa,Michela Bernardini,Tullio Genova,Guillaume Grolezet al. BMC Cancer, 2013, 14 (1), pp.939 Article dans une revue inserm-01122893v1
Emerging role of TRP channels in cell migration: from tumor vascularization to metastasis Alessandra Fiorio Pla,Dimitra Gkika Frontiers in Physiology, 2013, 4, ⟨10.3389/fphys.2013.00311⟩ Article dans une revue hal-04503128v1
Opiates Modulate Thermosensation by Internalizing Cold Receptor TRPM8 George Shapovalov,Dimitra Gkika,Maily Devilliers,Artem Kondratskyi,Dmitri Gordienkoet al. Cell Reports, 2013, 4 (3), pp.504-515. ⟨10.1016/j.celrep.2013.07.002⟩ Article dans une revue hal-04039045v1
TRPV2 Mediates Adrenomedullin Stimulation of Prostate and Urothelial Cancer Cell Adhesion, Migration and Invasion Agathe Oulidi,Alexandre Bokhobza,Dimitra Gkika,Fabien Vanden Abeele,V'Yacheslav Lehen'Kyiet al. PLoS ONE, 2013, 8 (5), pp.e64885. ⟨10.1371/journal.pone.0064885⟩ Article dans une revue hal-01708095v1
From urgency to frequency: facts and controversies of TRPs in the lower urinary tract Roman Skryma,Natalia Prevarskaya,Dimitra Gkika,Yaroslav Shuba Nature Reviews Urology, 2011, 8 (11), pp.617-630. ⟨10.1038/nrurol.2011.142⟩ Article dans une revue hal-04503131v1
Complex Regulation of the TRPM8 Cold Receptor Channel Alexis Bavencoffe,Artem Kondratskyi,Dimitra Gkika,Brigitte Mauroy,Yaroslav Shubaet al. Journal of Biological Chemistry, 2011, 286 (11), pp.9849-9855. ⟨10.1074/jbc.M110.162016⟩ Article dans une revue hal-04039058v1
TRP channels in prostate cancer: the good, the bad and the ugly? Dimitra Gkika,Natalia Prevarskaya Asian Journal of Andrology, 2011, 13 (5), pp.673-676. ⟨10.1038/aja.2011.18⟩ Article dans une revue hal-04503134v1
Role of cationic channel TRPV2 in promoting prostate cancer migration and progression to androgen resistance Michaël Monet,V'Yacheslav Lehen'Kyi,Florian Gackiere,Virginie Firlej,Matthieu Vandenbergheet al. Cancer Research, 2010, 285 (13), pp.9410-9419. ⟨10.1158/0008-5472.CAN-09-2205⟩ Article dans une revue hal-04039081v1
The Transient Receptor Potential Channel TRPM8 Is Inhibited via the α2A Adrenoreceptor Signaling Pathway Alexis Bavencoffe,Dimitra Gkika,Artem Kondratskyi,Benjamin Beck,Anne-Sophie Borowiecet al. Journal of Biological Chemistry, 2010, 285 (13), pp.9410-9419. ⟨10.1074/jbc.M109.069377⟩ Article dans une revue hal-03060332v1
PSA reduces prostate cancer cell motility by stimulating TRPM8 activity and plasma membrane expression. Dimitra Gkika,Matthieu Flourakis,Loic Lemonnier,Natalia Prevarskaya Oncogene, 2010, epub ahead of print. ⟨10.1038/onc.2010.210⟩ Article dans une revue inserm-00492444v1
Molecular mechanisms of TRP regulation in tumor growth and metastasis Dimitra Gkika,Natalia Prevarskaya Biochimica et Biophysica Acta - Molecular Cell Research, 2009, 1793 (6), pp.953-958. ⟨10.1016/j.bbamcr.2008.11.010⟩ Article dans une revue hal-04503178v1
Lysophospholipids stimulate prostate cancer cell migration via TRPV2 channel activation Michaël Monet,Dimitra Gkika,V'Yacheslav Lehen'Kyi,Albin Pourtier,Fabien Vanden Abeeleet al. Biochimica et Biophysica Acta - Molecular Cell Research, 2009, 1793 (3), pp.528-539. ⟨10.1016/j.bbamcr.2009.01.003⟩ Article dans une revue hal-04039097v1
Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function Dimitra Gkika,Catalin Topala,Qing Chang,Nicolas Picard,Stéphanie Thébaultet al. Journal of Clinical Investigation, 2007, 117 (6), pp.1647-1657. ⟨10.1172/JCI30168⟩ Article dans une revue hal-04039106v1
Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function Gabriel Bidaux,Matthieu Flourakis,Stéphanie Thebault,Alexander Zholos,Benjamin Becket al. Journal of Clinical Investigation, 2007, 117 (6), pp.1647-1657. ⟨10.1172/JCI30168⟩ Article dans une revue hal-03060259v1
Tissue kallikrein stimulates Ca2+ reabsorption via PKC-dependent plasma membrane accumulation of TRPV5 Dimitra Gkika,Catalin Topala,Qing Chang,Nicolas Picard,Stéphanie Thébaultet al. EMBO Journal, 2006, 25 (20), pp.4707-4716. ⟨10.1038/sj.emboj.7601357⟩ Article dans une revue hal-04040053v1
Critical Role of the Epithelial Ca2+ Channel TRPV5 in Active Ca2+ Reabsorption as Revealed by TRPV5/Calbindin-D28K Knockout Mice Dimitra Gkika,Yu-Juei Hsu,Annemiete van der Kemp,Sylvia Christakos,René Bindelset al. Journal of the American Society of Nephrology, 2006, 17 (11), pp.3020-3027. ⟨10.1681/ASN.2006060676⟩ Article dans une revue hal-04040054v1
The immunophilin FKBP52 inhibits the activity of the epithelial Ca 2+ channel TRPV5 Dimitra Gkika,Catalin Topala,Joost Hoenderop,René Bindels American Journal of Physiology. Renal Physiology, 2006, 290 (5), pp.F1253-F1259. ⟨10.1152/ajprenal.00298.2005⟩ Article dans une revue hal-04040056v1
Regulation of gene expression by dietary Ca2+ in kidneys of 25-hydroxyvitamin D3-1α-hydroxylase knockout mice Joost G.J. Hoenderop,Helena Chon,Dimitra Gkika,Hans A.R. Bluyssen,Frank C.P. Holstegeet al. Kidney International, 2004, 65 (2), pp.531-539. ⟨10.1111/j.1523-1755.2004.00402.x⟩ Article dans une revue hal-04040079v1
80K-H as a New Ca2+ Sensor Regulating the Activity of the Epithelial Ca2+ Channel Transient Receptor Potential Cation Channel V5 (TRPV5) Dimitra Gkika,Frank Mahieu,Bernd Nilius,Joost G.J. Hoenderop,René J.M. Bindels Journal of Biological Chemistry, 2004, 279 (25), pp.26351-26357. ⟨10.1074/jbc.M403801200⟩ Article dans une revue hal-04040058v1
A novel myeloid-like NK cell progenitor in human umbilical cord blood Sonia Perez,Panagiota Sotiropoulou,Dimitra Gkika,Louisa Mahaira,Dimitrios Niarchoset al. Blood, 2003, 101 (9), pp.3444-3450. ⟨10.1182/blood-2002-05-1501⟩ Article dans une revue hal-04040069v1
Functional expression of the epithelial Ca2+ channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex S. F.J. van de Graaf,Stan F J van De Graaf,Joost G J Hoenderop,Dimitra Gkika,Dennis Lamerset al. EMBO Journal, 2003, 22 (7), pp.1478-1487. ⟨10.1093/emboj/cdg162⟩ Article dans une revue hal-04040078v1

Chapitre d'ouvrage (1)

Transient Receptor Potential (TRP) Channels non Genomic Regulation by Sex Steroids: The Less Traveled Pathway Monika Haoui,Dimitra Gkika Encyclopedia of Cell Biology, Elsevier, pp.271-277, 2023, ⟨10.1016/B978-0-12-821618-7.00170-X⟩ Chapitre d'ouvrage hal-04503090v1

Communication dans un congrès (1)

Non genomic regulation of TRPM8: From thermosensation to cancer Dimitra Gkika Biophysical Society 66th Annual Meeting, Feb 2022, San Francisco (CA, USA), United States. pp.101a, ⟨10.1016/j.bpj.2021.11.2206⟩ Communication dans un congrès hal-04503223v1