Élie Besserer-Offroy

Identifiants chercheurs

IdHAL :

ebesserer-offroy

ORCID :

0000-0002-7473-7043

arXiv :

bessereroffroy_e_1

ResearcherID :

K-5513-2014

Publications

Article dans une revue (11)

A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor Rebecca L Brouillette,Christine E Mona,Michael Desgagné,Malihe Hassanzedeh,Émile Breaultet al. Pharmacological Research, 2025, 212, pp.107597. ⟨10.1016/j.phrs.2025.107597⟩ Article dans une revue hal-04877786v1
Structure-based design of macrocyclic peptides to generate functional antibodies against G protein-coupled receptors Marie-Edith Nepveu-Traversy,Malihe Hassanzadeh,Laurent Bruneau-Cossette,Élie Besserer-Offroy,Rebecca Brouilletteet al. Nature Communications, 2025, 16 (1), pp.11215. ⟨10.1038/s41467-025-66030-1⟩ Article dans une revue hal-05433167v1
Opioid Analgesics: Rise and Fall of Ligand Biased Signaling and Future Perspectives in the Quest for the Holy Grail Émile Breault,Rebecca L Brouillette,Terence E Hébert,Philippe Sarret,Elie Besserer-Offroy CNS Drugs, 2025, 39 (6), pp.565-581. ⟨10.1007/s40263-025-01172-w⟩ Article dans une revue (article de synthèse) inserm-05017491v1
A neurotensin receptor type 1-derived pepducin acts as a biased allosteric modulator to regulate target receptor function Rebecca Brouillette,Frédérique Lussier,Émile Breault,Nathan Meneboo,Malihe Hassanzadehet al. Acta Pharmaceutica Sinica B, 2025, Online ahead of print. ⟨10.1016/j.apsb.2025.12.043⟩ Article dans une revue inserm-05441447v1
Size-Reduced Macrocyclic Analogues of [Pyr 1 ]-apelin-13 Showing Negative Gα 12 Bias Still Produce Prolonged Cardiac Effects Kien Tran,Xavier Sainsily,Jérôme Côté,David Coquerel,Pierre Couvineauet al. Journal of Medicinal Chemistry, 2022, 65 (1), pp.531-551. ⟨10.1021/acs.jmedchem.1c01708⟩ Article dans une revue hal-04015710v1
Metabolically stable neurotensin analogs exert potent and long-acting analgesia without hypothermia Mélanie Vivancos,Roberto Fanelli,Élie Besserer-Offroy,Sabrina Beaulieu,Magali Chartieret al. Behavioural Brain Research, 2021, 405, pp.113189. ⟨10.1016/j.bbr.2021.113189⟩ Article dans une revue hal-03155317v1
Data set describing the in vitro biological activity of JMV2009, a novel silylated neurotensin(8-13) analog Elie Besserer-Offroy,Pascal Tétreault,Rebecca L Brouillette,Adeline René,Alexandre Murzaet al. Data in Brief, 2020, 31, pp.105884. ⟨10.1016/j.dib.2020.105884⟩ Article dans une revue (data paper) hal-03022455v1
Pain relief devoid of opioid side effects following central action of a silylated T neurotensin analog Pascal Tétreault,Élie Besserer-Offroy,Rebecca L Brouillette,Adeline René,Alexandre Murzaet al. European Journal of Pharmacology, 2020, ⟨10.1016/j.ejphar.2020.173174⟩ Article dans une revue hal-03022448v1
Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues Roberto Fanelli,Nicolas Floquet,Élie Besserer-Offroy,Bartholomé Delort,Mélanie Vivancoset al. Journal of Medicinal Chemistry, 2017, 60 (8), pp.3303-3313. ⟨10.1021/acs.jmedchem.6b01848⟩ Article dans une revue hal-02322191v1
Stereoselective Synthesis of β-(5-Arylthiazolyl) α-Amino Acids and Use in Neurotensin Analogues Denisa Hapău,Emmanuelle Rémond,Roberto Fanelli,Mélanie Vivancos,Adeline Renéet al. European Journal of Organic Chemistry, 2016, 2016 (5), pp.1017-1024. ⟨10.1002/ejoc.201501495⟩ Article dans une revue istex hal-03566472v1
Synthesis and Characterization in Vitro and in Vivo of ( l )-(Trimethylsilyl)alanine Containing Neurotensin Analogues Roberto Fanelli,Élie Besserer-Offroy,Adeline René,Jérôme Côté,Pascal Tétreaultet al. Journal of Medicinal Chemistry, 2015, 58 (19), pp.7785-7795. ⟨10.1021/acs.jmedchem.5b00841⟩ Article dans une revue hal-03566154v1