Eloise Thomas Eloïse Thomas - Maîtresse de ConférencesUniversité Claude Bernard Lyon 1, FranceLAGEPP : Laboratoire d'Automatique, de Génie des Procédés et de Génie Pharmaceutique - UMR5007 CNRS - France.ISPB : Institut des Sciences Pharmaceutiques et Biologiques - Faculté de Pharmacie de Lyon - France.

Identifiants chercheurs

IdHAL :

eloise-thomas

ORCID :

0000-0002-3772-872X

IdRef :

204202027

ResearcherID :

http://www.researcherid.com/rid/Y-2383-2019

Présentation

Thématique de recherche :Génie Pharmaceutique, formulation de produits de santé

Systèmes de délivrance contrôlée et/ou ciblée d’actifs thérapeutiques (nanoparticules, hydrogels, microparticules)

Formulation d’agents de contraste pour l’imagerie médicale et plateformes théranostiques

Décontamination contre les toxiques

Synthèse, caractérisations physico-chimiques, évaluation in vitro et in vivo sur petit animal

Publications

Article dans une revue (22)

Smart zwitterionic biodegradable hydrogel for sustained peptide delivery: Application to the neurotherapeutic peptide NX210c Elise Rosson,Eloise Thomas,Jacqueline Sidi-Boumedine,David Kryza,Marie Coudercet al. Biomaterials Advances, 2026, 178, pp.214437. ⟨10.1016/j.bioadv.2025.214437⟩ Article dans une revue hal-05291454v1
Focus on therapeutic peptides and their delivery Elise Rosson,François Lux,L. David,Yann Godfrin,Olivier Tillementet al. International Journal of Pharmaceutics, 2025, 675, pp.125555. ⟨10.1016/j.ijpharm.2025.125555⟩ Article dans une revue (article de synthèse) hal-05078046v1
Functionalization of chitosan with a polycarboxylic macrocycle yields injectable hydrogel with pH and salts responsiveness Arthur Durand,Thomas Gréa,Gabin Lebeau,Guillaume Jacquot,Augustin Tillementet al. Materials Today Advances, 2025, 25, pp.100565. ⟨10.1016/j.mtadv.2025.100565⟩ Article dans une revue hal-04967331v1
Tailor-Made Synthesis of Cerium Oxide Nanoparticles for Improving the Skin Decontamination of Paraoxon Eloise Thomas,Stephanie Briancon,Frédéric Chaput,Greta Camilla Magnano,Isabelle Trenqueet al. ACS Applied Nano Materials, 2024, 7, pp.16052-16065. ⟨10.1021/acsanm.4c01830⟩ Article dans une revue hal-04672854v1
Anti-Netrin-1 decorated nanoparticles combined with chemotherapy for the treatment of triple-negative breast cancer Silvia Breusa,Eloise Thomas,Noemi Baldinotti,Serena Zilio,Jean-Guy Delcroset al. Biomaterials Advances, 2024, 161, pp.213881. ⟨10.1016/j.bioadv.2024.213881⟩ Article dans une revue hal-04577330v1
CeO2-based peelable gel for neutralization and skin decontamination toward chemical warfare agents Eloise Thomas,Claire Bordes,Fréderic Chaput,Delphine Arquier,Stéphanie Briançonet al. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2024, 687, pp.133520. ⟨10.1016/j.colsurfa.2024.133520⟩ Article dans une revue hal-04480655v1
Combating lead and cadmium exposure with an orally administered chitosan-based chelating polymer Jordyn Ann Howard,Halyna Kuznietsova,Natalia Dziubenko,Axel Aigle,Marco Natuzziet al. Scientific Reports, 2023, 13 (1), pp.2215. ⟨10.1038/s41598-023-28968-4⟩ Article dans une revue hal-04209149v1
Subcutaneous Administration of a Zwitterionic Chitosan‐Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies Thomas Gréa,Guillaume Jacquot,Arthur Durand,Clélia Mathieu,Adeline Gasseret al. Advanced Materials, 2023, 36 (13), pp.2308738. ⟨10.1002/adma.202308738⟩ Article dans une revue hal-04728163v1
Anti-BCMA Immuno-NanoPET Radiotracers for Improved Detection of Multiple Myeloma Eloise Thomas,Clélia Mathieu,Patricia Moreno‐gaona,Vincent Mittelheisser,François Luxet al. Advanced Healthcare Materials, 2021, pp.2101565. ⟨10.1002/adhm.202101565⟩ Article dans une revue hal-03469640v1
3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation Irini Skaripa-Koukelli,David Hauton,John Walsby-Tickle,Eloise Thomas,Joshua Owenet al. Cancer & metabolism, 2021, 9 (1), ⟨10.1186/s40170-021-00273-6⟩ Article dans une revue hal-03379071v1
Feasibility study and direct extraction of endogenous free metallic cations combining hemodialysis and chelating polymer Marco Natuzzi,Coralie Grange,Thomas Gréa,Thomas Brichart,Axel Aigleet al. Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-99462-y⟩ Article dans une revue hal-03379081v1
Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation Joshua Owen,Eloise Thomas,Jyothi Menon,Michael Gray,Irini Skaripa-Koukelliet al. Journal of Controlled Release, 2020, 319, pp.222-233. ⟨10.1016/j.jconrel.2019.12.045⟩ Article dans une revue hal-02547889v1
Functionalization of theranostic AGuIX® nanoparticles for PET/MRI/optical imaging Vivek Thakare,Vu-Long Tran,Marco Natuzzi,Eloise Thomas,Mathieu Moreauet al. RSC Advances, 2019, 9 (43), pp.24811-24815. ⟨10.1039/C9RA00365G⟩ Article dans une revue hal-02287597v1
Multimodal AGuIX® Nanoparticles: Size Characterization by HF5 and Optimization of the Radiolabeling with Various SPECT/PET/Theranostic Tracers S. Huclier-Markai,E. Ntsiba,Eloise Thomas,C. Alliot,Cs Cutleret al. Int.J.Med.Nano Res., 2019, 6 (1), pp.027. ⟨10.23937/2378-3664.1410027⟩ Article dans une revue hal-02317372v1
AGuIX® from bench to bedside—Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine François Lux,Vu Long Tran,Eloise Thomas,Sandrine Dufort,Fabien Rossettiet al. British Journal of Radiology, 2019, 92 (1093), pp.20180365. ⟨10.1259/bjr.20180365⟩ Article dans une revue (article de synthèse) hal-01935540v1
Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy Eloise Thomas,Jyothi Menon,Joshua Owen,Irini Skaripa-Koukelli,Sheena Wallingtonet al. Theranostics, 2019, 9 (19), pp.5595-5609. ⟨10.7150/thno.34669⟩ Article dans une revue hal-02287691v1
Proton MR spectroscopy and diffusion MR imaging monitoring to predict tumor response to interstitial photodynamic therapy for glioblastoma Magali Toussaint,Sophie Pinel,Florent Auger,Nicolas Durieux,Magalie Thomassinet al. Theranostics, 2017, 7 (2), pp.436-451. ⟨10.7150/thno.17218⟩ Article dans une revue hal-01399256v1
Ultrasmall Silica-Based Bismuth Gadolinium Nanoparticles for Dual Magnetic Resonance–Computed Tomography Image Guided Radiation Therapy Alexandre Detappe,Eloise Thomas,Mark W Tibbitt ||,Sijumon Kunjachan,Oksana Zavidijet al. Nano Letters, 2017, 17 (3), pp.1733 - 1740. ⟨10.1021/acs.nanolett.6b05055⟩ Article dans une revue hal-01689566v1
68 Ga-radiolabeled AGuIX nanoparticles as dual-modality imaging agents for PET/MRI-guided radiation therapy Penelope Bouziotis,Dimitris Stellas,Eloise Thomas,Charles Truillet,Charalampos Tsoukalaset al. Nanomedicine, 2017, 12 (13), pp.1561 - 1574. ⟨10.2217/nnm-2017-0032⟩ Article dans une revue hal-01689547v1
Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma Eloise Thomas,Ludovic Colombeau,Mickaël Gries,Thibaut Peterlini,Clélia Mathieuet al. International Journal of Nanomedicine, 2017, 12, pp.7075-7088. ⟨10.2147/IJN.S141559⟩ Article dans une revue hal-01643075v1
Synthesis and Characterization of 89 Zr-Labeled Ultrasmall Nanoparticles Charles Truillet,Eloise Thomas,François Lux,Loc T Huynh,Olivier Tillementet al. Molecular Pharmaceutics, 2016, 13 (7), pp.2596 - 2601. ⟨10.1021/acs.molpharmaceut.6b00264⟩ Article dans une revue hal-01405878v1
Long-Term in Vivo Clearance of Gadolinium-Based AGuIX Nanoparticles and Their Biocompatibility after Systemic Injection Lucie Sancey,Shady Kotb,Charles Truillet,F. Appaix,Arthur Maraiset al. ACS Nano, 2015, 9 (3), pp.2477-2488. ⟨10.1021/acsnano.5b00552⟩ Article dans une revue hal-01207383v1

Brevet (1)

Bismuth-Gadolinium Nanoparticles Ross Berbeco,Eloise Thomas,François Lux,Olivier Tillement,Alexandre Detappeet al. United States, Patent n° : WO2018107057 (A1). 2018 Brevet hal-02548425v1

Thèse (1)

Développement d’une seconde génération de nanoparticules AGuIX pour des applications théranostiques en oncologie Eloise Thomas Cancer. Université de Lyon, 2017. Français. ⟨NNT : 2017LYSE1121⟩ Thèse tel-01674228v1

Communication dans un congrès (18)

Zwitterionic Biodegradable Hydrogels for Sustained Therapeutic Peptide Delivery Elise Rosson,Eloise Thomas,Alexandra Weber,Jacqueline Taleb Sidi-Boumedine,David Kryzaet al. Nanohybrid XXI, May 2025, Porquerolles, France Communication dans un congrès hal-05078087v1
Biodegradable hydrogel for sustained release of therapeutic peptide for the treatment of neurological pathologies Elise Rosson,François Lux,Alexandra Weber,Jacqueline Sidi Boumedine,David Kryzaet al. Advanced Drug and Gene Delivery Systems symposium, Jan 2025, Lyon, France Communication dans un congrès hal-04924331v1
Imagerie K-edge couleur par SPCCT avec des éléments à Z élevé pour l’imagerie fonctionnelle du poumon : étude fantôme. Agnieszka Gutwinska,Derick Rosario,Antoine Robert,Eloise Thomas,Amanda Panget al. Journée Francophone de Radiologie 2025, Oct 2025, Paris, France Communication dans un congrès hal-05370902v1
Biodegradable hydrogel for sustained release of therapeutic peptide Elise Rosson,Eloise Thomas,François Lux,Alexandra Weber,Jacqueline Sidi-Boumedineet al. Nanohybrid XX, May 2024, Bastia, France Communication dans un congrès hal-04694239v1
Biodegradable hydrogel for sustained release of therapeutic peptide for the treatment of neurological pathologies Elise Rosson,François Lux,Alexandra Weber,Jacqueline Sidi Boumedine,David Kryzaet al. BNLF 2024 CRS meeting, BNLF local chapter CRS, Oct 2024, Ghent, Belgium Communication dans un congrès hal-04765505v1
Peptide formulation and development of a novel delivery system for the treatment of neurological pathologie Elise Rosson,Eloise Thomas,François Lux,Alexandra Weber,Thomas Brichartet al. Nanohybrides XIX, May 2023, Porquerolles, France Communication dans un congrès hal-04691977v1
Towards the Synthesis and Delivery of Halogenated MCT1 Substrates Irini Skaripa-Koukelli,John Walsby-Tickle,Joshua Owen,Eloise Thomas,James Mccullaghet al. Oncological Drug Delivery Conference, Sep 2019, Oxford, United Kingdom Communication dans un congrès hal-03989472v1
Ultrasound-Induced Mircobubble Cavitation For Optimisation Of Tumour Uptake Of Liposome-Based Chemo-Radionuclide Therapy Katherine A. Vallis,Eloise Thomas,Jyothi Menon,Joshua Owen,Sheena Wallingtonet al. Annual Congress of the European Association of Nuclear Medicine, Oct 2019, Barcelona, Spain. pp.1-952, ⟨10.1007/s00259-019-04486-2⟩ Communication dans un congrès hal-02548480v1
Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma Noémie Thomas,Mickaël Gries,Ludovic Colombeau,Eloise Thomas,Cédric Bouraet al. International Conference on Porphyrins and Phthalocyanines, ICCP-10, Jul 2018, Munich, Germany Communication dans un congrès hal-01845326v1
AGuIX® theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of brain tumors Ludovic Colombeau,Eloise Thomas,Noémie Thomas,Muriel Barberi-Heyob,François Luxet al. 17th Congress of the European Society for Photobiology, Sep 2017, Pise, Italy Communication dans un congrès hal-02550754v1
Functionalization of AGuIX nanoparticles for improved radiotherapy Eloise Thomas,Alexandre Detappe,Ross Berbeco,François Lux,Olivier Tillement Nano-Hybrides n°14, May 2017, Bastia, France Communication dans un congrès hal-02548188v1
Gadolinium-based nanoparticles for the treatment of glioblastoma by MRI-guided photodynamic therapy Eloise Thomas,Magali Toussaint,Ludovic Colombeau,Mickaël Gries,Thibaut Peterliniet al. World Molecular Imaging Congress, WMIC 2017, Sep 2017, Philadelphia, United States Communication dans un congrès hal-02548177v1
Vascular targeting for the treatment of glioblastoma by PDT Céline Frochot,Ludovic Colombeau,Eloise Thomas,Régis Vanderesse,Magali Toussaintet al. 16th International Photodynamic Association World Congress, IPA 2017, Jun 2017, Coimbra, Portugal Communication dans un congrès hal-03243053v1
Use of MR Imaging and proton MR Spectroscopy imaging monitoring to predict tumor response to interstitial photodynamic therapy for glioblastoma Magali Toussaint,Florent Auger,Sophie Pinel,Magalie Thomassin,Eloise Thomaset al. Photodynamic Therapy and Photodiagnosis update, Oct 2016, Nancy, France Communication dans un congrès hal-01407476v1
Interstitial photodynamic therapy for glioblastoma: interest of MRI monitoring to predict iPDT effects. Magali Toussaint,Florent Auger,Sophie Pinel,Nicolas Durieux,Magalie Thomassinet al. 13e Colloque Nano-hybrides, ILM, Lyon 1, May 2016, Porquerolles, France Communication dans un congrès hal-01312929v1
Ultrasmall nanoparticles functionalization for PET and SPECT imaging Eloise Thomas,François Lux,Olivier Tillement Nano-Hybrides n°12, May 2015, Bastia, France Communication dans un congrès hal-02548199v1
Development of new synthesis protocol and advanced characterization of AGuIX Nanoparticle Vu Long Tran,Arthur Marais,Eloise Thomas,Cédric Louis,François Luxet al. ITN-ARGENT, Nov 2015, Obergurgl, Austria Communication dans un congrès hal-03989480v1
AGuIX nanoparticles for PET/MRI François Lux,Lucie Sancey,Eloise Thomas,Olivier Tillement France Life Imaging, Dec 2014, Lyon, France Communication dans un congrès hal-02548210v1

Poster de conférence (19)

Development of metal-based contrast agents for Spectral Photon counting computed Tomography (SPCCT) scanner Priusha Ravipati,Yves Chevalier,Agnieszka Gutwinska,Salim Si-Mohamed,Stephanie Brianconet al. European Molecular Imaging Meeting, Mar 2025, Bilbao, Spain Poster de conférence hal-05078095v1
Preparation of nanoemulsion encapsulating sensitive biomacromolecule by premix membrane emulsification Solène Fukuhara,C. Charcosset,Eloise Thomas BNLF 2024 CRS meeting, Oct 2024, Ghent, Belgium Poster de conférence hal-04765479v1
Development of metal loaded nanoparticles as contrast agents for Spectral Photon counting computed Tomography (SPCCT) scanner Priusha Ravipati,Yves Chevalier,Agnieszka Gutwinska,Salim Si-Mohamed,Stephanie Brianconet al. SF Nano, Dec 2024, Toulouse, France Poster de conférence hal-04924322v1
Biodegradable hydrogel for sustained release of therapeutic peptide Elise Rosson,Eloise Thomas,Alexandra Weber,Jacqueline Sidi-Boumedine,David Kryzaet al. PBP world meeting (Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology), Mar 2024, Vienne (AUT), Austria Poster de conférence hal-04694250v1
Preparation of nanoemulsion encapsulating sensitive biomacromolecule by premix membrane emulsification Solène Fukuhara,C. Charcosset,Eloise Thomas SF Nano, Dec 2024, Toulouse, France Poster de conférence hal-04924327v1
Development of metal loaded nanoparticles as contrast agents for Spectral Photon counting computed Tomography (SPCCT) scanner Priusha Ravipati,Yves Chevalier,Agnieszka Gutwinska,Salim Si-Mohamed,Stephanie Brianconet al. BNLF 2024 CRS meeting, Oct 2024, Ghent, Belgium Poster de conférence hal-04765470v1
CeO2-based peelable gel for neutralization and skin decontamination toward chemical warefare agent simulants Eloise Thomas,Delphine Arquier,C. Barratier,Claire Bordes,Fréderic Chaputet al. Formula XI, Jul 2023, Lille, France Poster de conférence hal-04462743v1
Monoclonal antibodies decorated nanoparticles for the treatment of triple negative breast cancer Silvia Breusa,Jean‐guy Delcros,Eloise Thomas,Serena Zilio,Diana Marcela Hernandez Palominoet al. SFNano Annual Meeting, Dec 2022, Strasbourg, France Poster de conférence hal-03989500v1
Ultrasound-Mediated Cavitation To Enhance The Delivery Of Liposomal Formulations For Targeted Radionuclide Therapy Eloise Thomas,Jyothi Menon,Joshua Owen,Sheena Wallington,Michael Grayet al. Controlled Release Society Annual Meeting, Jul 2019, Valencia, Spain Poster de conférence hal-02548225v1
Ultrasound And Microbubbles Enhance The Delivery Of A Liposomal Formulation For Targeted Chemo-Radionuclide Therapy Eloise Thomas,Jyothi Menon,Joshua Owen,Sheena Wallington,Michael Grayet al. British Nuclear Medicine Society Spring Meeting, Apr 2019, Oxford, United Kingdom Poster de conférence hal-02548236v1
Indium-111 afterloading of preformed EGF containing liposomes for molecularly targeted radionuclide delivery via ultrasound induced cavitation. Joshua Owen,Jyothi Menon,Eloise Thomas,Irini Skaripa-Koukelli,Martin Gillet al. Annual Congress of the European Association of Nuclear Medicine, Oct 2018, Düsseldorf, Germany. European Journal of Nuclear Medicine and Molecular Imaging, 45 (S1), pp.1-844, 2019, ⟨10.1007/s00259-018-4148-3⟩ Poster de conférence hal-02548464v1
Targeted and combined chemo-radionucleide therapy for the treatment of breast cancers Eloise Thomas,Jyothi Menon,Joshua Owen,Irini Skaripa-Koukelli,Robert Carlisleet al. CRUK Symposium, Jun 2018, Oxford, United Kingdom Poster de conférence hal-02548247v1
Silica-Based Bismuth-Gadolinium Nanoparticles for MRI and CT Image-Guided Radiation Therapy Alexandre Detappe,Eloise Thomas,M. Tibbitt,S. Kunjachan,O. Zavidijet al. ASTRO annual meeting, Sep 2017, San Diego, United States Poster de conférence hal-03989491v1
PET and MR imaging with 64Cu/68Ga-labeled AGuIX ultra-small nanoparticles in tumor-bearing mice Marie-Caline Abadjian,Eloise Thomas,Joseph Latoche,Lesley Foley,Kathryn Dayet al. SNMMI Annual Meeting, Jun 2016, San Diego, United States. 57 (Supplement2), pp.1181, 2016 Poster de conférence hal-02548345v1
AGUIX® theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of brain tumors Ludovic Colombeau,Eloise Thomas,Thibaut Peterlini,Mickaël Gries,Noémie Thomaset al. Photodynamic Therapy and Photodiagnosis update, Oct 2016, Nancy, France. , 17, pp.A71, 2017, ⟨10.1016/j.pdpdt.2017.01.161⟩ Poster de conférence istex hal-01408883v1
Radiolabeling for long term biodistribution of ultrasmall nanoparticles designed for radiotherapy guided by MRI Eloise Thomas,Charles Truillet,Franck Denat,François Lux,Frederic Boschettiet al. World Molecular Imaging Congress, Sep 2016, New-York, United States Poster de conférence hal-02548258v1
Ultrasmall gadolinium-based nanoparticles designed for photodynamic therapy (PDT) guided by MRI E Thomas,M Toussaint,Ludovic Colombeau,Céline Frochot,Régis Vanderesseet al. Photodynamic Therapy and Photodiagnosis update, Oct 2016, Nancy, France. , Photodiagnosis and Photodynamic Therapy, 17, pp.A60, 2017, ⟨10.1016/j.pdpdt.2017.01.136⟩ Poster de conférence hal-01498485v1
Functionalization of ultrasmall nanoparticles for theranosctic applications Eloise Thomas,Frederic Boschetti,Franck Denat,François Lux,Olivier Tillement COST TD1004 Action Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery, Oct 2015, Belgrade, Serbia Poster de conférence hal-02548269v1
AGuIX modifications for active tumor targeting and radiolabelling Eloise Thomas,Charles Truillet,Marie Plissonneau,Frederic Boschetti,Franck Denatet al. COST TD1004 Action Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery, Oct 2014, Istanbul, Turkey Poster de conférence hal-02548293v1