Emilie Roger

Publications

Article dans une revue (34)

Specific quantification of intact lipid nanocapsules in rats using FRET: biodistribution and PBPK model development Rana Elfatairi,Jessica Ou,Vincent Lebreton,Mariam Mahdjoub,Norraseth Kaeokhamloedet al. Nanomedicine, 2025, 20 (10), pp.1101-1112. ⟨10.1080/17435889.2025.2492537⟩ Article dans une revue hal-05242719v1
Thymoquinone loaded lipid nanocapsule dispersion: two methods of preparation, characterization and in vitro evaluations for oral administration Mouna Selmi,Amine Trabelsi,Nolwenn Lautram,David Dallerac,Guillaume Lefebvreet al. Pharmaceutical Development and Technology, In press, ⟨10.1080/10837450.2024.2448616⟩ Article dans une revue hal-04875865v1
Nano-Ayurvedic Medicine Approaches Using Ginkgo biloba-Phytochemicals Functionalized Gold Nanoparticles Against Breast Cancer Velaphi Thipe,Nya Hall,Amoolya Pandurangi,Samuel Ajayi,Prosper Emehet al. Nanotechnology, Science and Applications, 2024, Volume 17, pp.189-210. ⟨10.2147/NSA.S478533⟩ Article dans une revue hal-05173395v1
Internalization and mechanisms of toxicity of lipid nanocapsules in HepG2 and HepaRG hepatoma cells upon acute and chronic exposures Flavien Delaporte,Emilie Roger,Jérome Bejaud,Pascal Loyer,Frédéric Lagarceet al. International Journal of Pharmaceutics, 2024, 667, pp.124815. ⟨10.1016/j.ijpharm.2024.124815⟩ Article dans une revue hal-04751862v1
Thymoquinone-loaded lipid nanocapsules with promising anticancer activity for colorectal cancer Mouna Selmi,Abir Salek,Mahassen Barboura,Leila Njim,Amine Trabelsiet al. Nanoscale Advances, 2023, ⟨10.1039/d3na00445g⟩ Article dans une revue hal-04210022v1
Evidence of residual micellar structures in a lipid nanocapsule dispersion. A multi-technique approach Emilie Roger,Florence Franconi,Tran Anh Thu Do,Carl Simonsson,Benjamin Siegleret al. Journal of Controlled Release, 2023, 364, pp.700-717. ⟨10.1016/j.jconrel.2023.10.054⟩ Article dans une revue hal-04295223v1
Drug Delivery Systems for the Oral Administration of Antimicrobial Peptides: Promising Tools to Treat Infectious Diseases Caroline Deshayes,Md Arafath,Véronique Apaire-Marchais,Emilie Roger Frontiers in Medical Technology, 2022, 3, ⟨10.3389/fmedt.2021.778645⟩ Article dans une revue hal-03615302v1
Green nanotechnology—An innovative pathway towards biocompatible and medically relevant gold nanoparticles Velaphi Thipe,Alice Karikachery,Pinar Çakilkaya,Umer Farooq,Hussein Genedyet al. Journal of Drug Delivery Science and Technology, 2022, 70, ⟨10.1016/j.jddst.2022.103256⟩ Article dans une revue hal-03615301v1
Pharmacokinetics of intact lipid nanocapsules using new quantitative FRET technique Vincent Lebreton,Norraseth Kaeokhamloed,Anastasiia Vasylaki,Gregory Hilairet,Adélie Mellingeret al. Journal of Controlled Release, 2022, 351, pp.681-691. ⟨10.1016/j.jconrel.2017.03.005⟩ Article dans une revue hal-02341627v1
FRET as the tool for in vivo nanomedicine tracking Norraseth Kaeokhamloed,Samuel Legeay,Emilie Roger Journal of Controlled Release, 2022, 349, pp.156-173. ⟨10.1016/j.jconrel.2022.06.048⟩ Article dans une revue hal-03720790v1
A new method to prepare microparticles based on an Aqueous Two-Phase system (ATPS), without organic solvents Florence Dumas,Jean-Pierre Benoit,Patrick Saulnier,Emilie Roger Journal of Colloid and Interface Science, 2021, 599, pp.642-649. ⟨10.1016/j.jcis.2021.03.141⟩ Article dans une revue hal-03388118v1
Organic nanoparticle tracking during pharmacokinetic studies Samuel Bonnet,Rana Elfatairi,Florence Franconi,Emilie Roger,Samuel Legeay Nanomedicine, 2021, ⟨10.2217/nnm-2021-0155⟩ Article dans une revue hal-03446719v1
Aqueous Two-Phase Systems: simple one-step process formulation and phase diagram for characterisation Florence Dumas,Emilie Roger,Johanna Rodriguez,Lazhar Benyahia,Jean-Pierre Benoit Colloid and Polymer Science, 2020, ⟨10.1007/s00396-020-04748-8⟩ Article dans une revue hal-02973278v1
Nanocarriers and nonviral methods for delivering antiangiogenic factors for glioblastoma therapy: the story so far Anne Clavreul,Milad Pourbaghi-Masouleh,Emilie Roger,Philippe Menei International Journal of Nanomedicine, 2019, 14, pp.2497-2513. ⟨10.2147/IJN.S194858⟩ Article dans une revue hal-02616075v1
Advances in treatment formulations for acute myeloid leukemia Thomas Briot,Emilie Roger,Sylvain Thépot,Frédéric Lagarce Drug Discovery Today Biosilico, 2018, Epub ahead of print. ⟨10.1016/j.drudis.2018.05.040⟩ Article dans une revue inserm-01809889v1
Development and characterization of sorafenib-loaded lipid nanocapsules for the treatment of glioblastoma Anne Clavreul,Emilie Roger,Milad Pourbaghi-Masouleh,Laurent Lemaire,Clément Tétaudet al. Drug Delivery, 2018, 25 (1), pp.1756 - 1765. ⟨10.1080/10717544.2018.1507061⟩ Article dans une revue inserm-01908758v1
Development and in vitro evaluations of new decitabine nanocarriers for the treatment of acute myeloid leukemia Thomas Briot,Emilie Roger,Nolwenn Lautram,Alexis Verger,Anne Clavreulet al. International Journal of Nanomedicine, 2017, Volume 12, pp.8427 - 8442. ⟨10.2147/IJN.S147659⟩ Article dans une revue inserm-01668530v1
Human mesenchymal stromal cells as cellular drug-delivery vectors for glioblastoma therapy: a good deal? Anne Clavreul,Milad Pourbaghi-Masouleh,Emilie Roger,Nolwenn Lautram,Claudia Montero-Meneiet al. Journal of Experimental and Clinical Cancer Research, 2017, 36 (1), pp.135. ⟨10.1186/s13046-017-0605-2⟩ Article dans une revue inserm-01631360v1
Models for drug absorption from the small intestine: where are we and where are we going? Pierre-André Billat,Emilie Roger,Sébastien Faure,Frédéric Lagarce Drug Discovery Today, 2017, 22 (5), pp.761-775. ⟨10.1016/j.drudis.2017.01.007⟩ Article dans une revue hal-02615955v1
Spontaneous nano-emulsification: Process optimization and modeling for the prediction of the nanoemulsion’s size and polydispersity Guillaume Lefebvre,Jérémie Riou,Guillaume Bastiat,Emilie Roger,Kristen Frombachet al. International Journal of Pharmaceutics, 2017, 534 (1-2), pp.220-228. ⟨10.1016/j.ijpharm.2017.10.017⟩ Article dans une revue hal-02341597v1
Lipid nanocapsules maintain full integrity after crossing a human intestinal epithelium model Emilie Roger,Jean Christophe Gimel,Conor Bensley,Andrey S Klymchenko,Jean Pierre Benoit Journal of Controlled Release, 2017, 253, pp.11-18. ⟨10.1016/j.jconrel.2017.03.005⟩ Article dans une revue hal-03805634v1
Alginate/Chitosan Compact Polyelectrolyte Complexes: A Cell and Bacterial Repellent Material Thida Phoeung,Maria Vittoria Spanedda,Emilie Roger,Béatrice Heurtault,Sylvie Fournelet al. Chemistry of Materials, 2017, 29 (24), pp.10418-10425. ⟨10.1021/acs.chemmater.7b03863⟩ Article dans une revue hal-02142349v1
How to design the surface of peptide-loaded nanoparticles for efficient oral bioavailability? Hélène Malhaire,Jean-Christophe Gimel,Emilie Roger,Jean-Pierre Benoît,Frédéric Lagarce Advanced Drug Delivery Reviews, 2016, pp.1-17. ⟨10.1016/j.addr.2016.03.011⟩ Article dans une revue hal-01392464v1
On the Benefits of Rubbing Salt in the Cut: Self-Healing of Saloplastic PAA/PAH Compact Polyelectrolyte Complexes Andreas Reisch,Emilie Roger,Thida Phoeung,Cyril Antheaume,Camille Orthliebet al. Advanced Materials, 2014, 26 (16), pp.2547-2551. ⟨10.1002/adma.201304991⟩ Article dans une revue istex hal-01389168v1
Compact saloplastic poly(acrylic acid)/poly(allylamine) complexes: kinetic control over composition, microstructure, and mechanical properties Andreas Reisch,Patricia Tirado,Emilie Roger,Fouzia Boulmedais,Dominique Collinet al. Advanced Functional Materials, 2013, 23, pp.673-682 Article dans une revue hal-00966799v1
Catalytic Saloplastics: Alkaline Phosphatase Immobilized and Stabilized in Compacted Polyelectrolyte Complexes Patricia Tirado,Andreas Reisch,Emilie Roger,Fouzia Boulmedais,Loïc Jierryet al. Advanced Functional Materials, 2013, pp.4785-4792. ⟨10.1002/adfm.201300117⟩ Article dans une revue istex hal-01389162v1
Highly lipophilic fluorescent dyes in nano-emulsions: towards bright non-leaking nano-droplets. Andrey S Klymchenko,Emilie Roger,Nicolas Anton,Halina Anton,Ievgen Shulovet al. RSC Advances, 2012, 2 (31), pp.11876-11886. ⟨10.1039/c2ra21544f⟩ Article dans une revue hal-00783454v1
Development and characterization of a novel lipid nanocapsule formulation of Sn38 for oral administration Emilie Roger,Frédéric Lagarce,Jean-Pierre Benoît European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, 2011, 79 (1), pp.181-8. ⟨10.1016/j.ejpb.2011.01.021⟩ Article dans une revue istex hal-03165447v1
Reciprocal competition between lipid nanocapsules and P-gp for paclitaxel transport across Caco-2 cells. Emilie Roger,Frédéric Lagarce,Emmanuel Garcion,Jean-Pierre Benoît European Journal of Pharmaceutical Sciences, 2010, 40 (5), pp.422-9 Article dans une revue hal-03171843v1
The rise and rise of stealth nanocarriers for cancer therapy: passive versus active targeting Ngoc Trinh Huynh,Emilie Roger,Nolwenn Lautram,Jean-Pierre Benoît,Catherine Passirani-Malleret Nanomedicine, 2010, 5 (9), pp.1415-33. ⟨10.2217/nnm.10.113⟩ Article dans une revue hal-03171842v1
Biopharmaceutical parameters to concider in order to alter the fate of nanocarriers after oral delivery. Emilie Roger,Frédéric Lagarce,Emmanuel Garcion,Jean-Pierre Benoît Nanomedicine, 2010, 5 (2), pp.287-306 Article dans une revue hal-03171857v1
Lipid nanocapsules: Ready-to-use nanovectors for the aerosol delivery of paclitaxel José Hureaux,Frédéric Lagarce,Frédéric Gagnadoux,Laurent Vecellio,Anne Clavreulet al. European Journal of Pharmaceutics and Biopharmaceutics, 2009, 73 (2), pp.239 - 246. ⟨10.1016/j.ejpb.2009.06.013⟩ Article dans une revue istex hal-03165461v1
Lipid nanocarriers improve paclitaxel transport throughout human intestinal epithelial cells by using vesicle-mediated transcytosis Emilie Roger,Frédéric Lagarce,Emmanuel Garcion,Jean-Pierre Benoît Journal of controlled release : official journal of the Controlled Release Society, 2009, 140 (2), pp.174-81 Article dans une revue hal-03171849v1
The gastrointestinal stability of lipid nanocapsules Emilie Roger,Frédéric Lagarce,Jean-Pierre Benoît International Journal of Pharmaceutics, 2009, 379 (2), pp.260-5 Article dans une revue hal-03171870v1

Poster de conférence (15)

Intranasal route for glioblastoma stem cells treatment using synergistic inhibitors Cécile Doualle,Emilie Roger,Sifon Edem,Jérôme Bejaud,Patrick Saulnieret al. SFNano 2024, Dec 2024, Toulouse, France Poster de conférence hal-04849947v1
Development of lipid nanocapsule for oral treatment of liver cancer. Sihem Khelil,Nolwenn Lautram,David Dallerac,Marie-Claire Venier-Julienne,Camille Savaryet al. Journée de la SFR ICAT 2022, Jun 2022, Angers, France Poster de conférence hal-04105639v1
Experimental evidence of residual micellar structures in lipid nanocapsules suspensions Tran Anh Thu Do,Emilie Roger,Florence Franconi,Benjamin Siegler,Rodolphe Perrotet al. SFnano, Dec 2022, Strasbourg, France. Poster de conférence hal-03890468v1
In vitro evaluation of acute and chronic liver toxicity of lipid nanocapsules: what formulation for a better biocompatibility? Flavien Delaporte,Emilie Roger,Frédéric Lagarce,Camille Savary SFNano, Dec 2021, Angers, France Poster de conférence hal-03695357v1
Pharmacokinetics and oral absorption of different lipid nanocapsules: new quantitative FRET technique revealing PEGylation increasing the particle’s clearance Norraseth Kaeokhamloed,Vincent Lebreton,Jérôme Béjaud,Florence Gattacceca,Emilie Rogeret al. GMP 2021 Symposium, Oct 2021, Paris, France Poster de conférence hal-03528600v1
Population pharmacokinetic modelling of intravenous LNCs FRET in rat Vincent Lebreton,Norraseth Kaeokhamloed,Florence Gattacceca,Jérôme Béjaud,Patrick Saulnieret al. GMP 2021 Symposium, Oct 2021, Paris, France Poster de conférence hal-03528608v1
Aqueous Two Phase Systems: Physico-chemical Characterization By Phase Diagram Design Florence Dumas,Emilie Roger,Lazhar Benyahia,Jean-Pierre Benoit Controlled Release Society Annual Meeting & Exposition, Jul 2019, Valencia, Spain Poster de conférence hal-02613941v1
Design of phase diagrams for characterization of aqueous two-phase systems Florence Dumas,Johanna Rodriguez,Emilie Roger,Lazhar Benyahia,Jean-Pierre Benoit Journée scientifique de la SFR ICAT4208, 2018, Angers, France. , 2018 Poster de conférence hal-02616042v1
In vitro evaluations of new decitabine nanocarriers for the treatment of acute myeloid leukemia Thomas Briot,Emilie Roger,Nolwenn Lautram,Alexis Verger,Anne Clavreulet al. 4th annual meeting on Nanomedicine, 2017, Bordeaux, France. , 2017 Poster de conférence hal-02616000v1
Formulation of curcumin lipid nanocapsule-loaded gels for inflammatory bowel disease application Chithdavone Her,Marie-Claire Venier-Julienne,Emilie Roger La journée scientifique de la SFR ICAT, 2017, Angers, France. 2017 Poster de conférence hal-02615983v1
Formulation and characterization of &quot;water-in-water&quot; emulsion systems Florence Dumas,Emilie Roger,Lazhar Benyahia,Jean-Pierre Benoit SF Nano 2017, 2017, Bordeaux, France. , 2017 Poster de conférence hal-02616016v1
Formulation et caractérisation des systèmes d’émulsions dits « eau dans eau » Florence Dumas,Emilie Roger,Jean-Pierre Benoit Journée Scientifique de la SFR ICAT4208, 2017, Angers, France. , 2017 Poster de conférence hal-02616017v1
Development of decitabine nano objects for oral administration Thomas Briot,Emilie Roger,Frédéric Lagarce 4th Congress on Innovation in Drug Delivery, 2016, Antibes, France. 2016 Poster de conférence hal-02615971v1
New lipid nanocapsules for decitabine encapsulation Thomas Briot,Emilie Roger,Nolwenn Lautram,Frédéric Lagarce Journées annuelles SFNano, 2016, Paris, France. 2016 Poster de conférence hal-02615972v1
In vivo evaluation of novel lipid nanocapsule formulation of SN38 Emilie Roger,Frédéric Lagarce,Jean-Pierre Benoît 25 eme réunion annuelle du Groupe Thématique de Recherche sur les Vecteurs, 2010, Toulouse, France. 2010 Poster de conférence hal-03180842v1

Communication dans un congrès (13)

BEHAVIOR OF LIPID NANOCAPSULES AFTER ORAL ADMINISTRATION Emilie Roger Summer School « Innovations in Delivery and Targeting », Université de Strasbourg, Jun 2023, Strasbourg, France Communication dans un congrès hal-04268183v1
In vitro evaluation of acute and chronic liver toxicity of lipid nanocapsules Flavien Delaporte,Emilie Roger,Frédéric Lagarce,Camille Savary Journée de la Société Française de Recherche ICAT, Jun 2022, Angers, France Communication dans un congrès hal-03695378v1
Oral application of lipid nanocapsules: behavior of nanoparticles? Emilie Roger NANOMED EMJMD Workshop 2022, Jul 2022, Pavia, Italy Communication dans un congrès hal-03738515v1
In vitro evaluation of acute and chronic liver toxicity of lipid nanocapsules: what formulation for a better biocompatibility? Flavien Delaporte,Emilie Roger,Frédéric Lagarce,Camille Savary Société de Toxicologie Cellulaire et Moléculaire : Les Jeunes Toxicologues, Mar 2022, Online, France Communication dans un congrès hal-03695367v1
ORAL APPLICATION OF LIPID NANOCAPSULES: BEHAVIOR OF NANOPARTICLES? Emilie Roger 5th NANOMED Workshop "From biotechnology to nanobiotechnology and vaccines", University of Pavia, Jul 2022, Pavia, Italy Communication dans un congrès hal-04268193v1
Nanocapsules lipidiques : quelle taille pour une meilleure biocompatibilité hépatique ? Flavien Delaporte,Emilie Roger,Frédéric Lagarce,Camille Savary Journée de la Société Française de Recherche ICAT, Jun 2021, Angers, France Communication dans un congrès hal-03695306v1
In vitro evaluation of acute and chronic liver toxicity of lipid nanocapsules Flavien Delaporte,Emilie Roger,Catherine Passirani,Camille Savary Stratagem Cost, Sep 2021, Prague, Czech Republic Communication dans un congrès hal-03695352v1
Decitabine encapsulation in nanovector to improve acute myeloid leukemia treatment Jérôme Bejaud,Sylvain Thepot,Frédéric Lagarce,Thomas Briot,Emilie Rogeret al. Journée scientifique de la SFR ICAT 4208, 2018, Angers, France Communication dans un congrès hal-02616020v1
Lipid nanocapsules: a new platform for oral drug delivery system ? Emilie Roger 11th World Drug Delivery Summit, 2017, Baltimore, United States Communication dans un congrès hal-02615984v1
Combined strategy based on pre-activated analogs of oxazaphosphorines for increased therapeutic index and immune modulation Julia Delahousse,Charles Skarbek,Valentine Gauthier,Mélanie Desbois,Emilie Rogeret al. AACR Annual Meeting 2017, 2017, Washington, United States. ⟨10.1158/1538-7445.AM2017-2195⟩ Communication dans un congrès hal-02615988v1
Formulation and evaluation of new oxazaphosphorine prodrugs-loaded lipid nanocapsules for cancer treatment Henri Gonde,Emilie Roger,Charles Skarbek,Nolwenn Lautram,Angelo Paciet al. 4th Congress on Innovation in Drug Delivery (APGI/ADRITELF), 2016, Juan les Pins, France Communication dans un congrès hal-02615967v1
New oxazaphosphorine prodrug’s for immunotherapy and n anomedicine against cancer Charles Skarbek,Henri Gonde,Mélanie Desbois,Julia Delahousse,Nathalie Chapus-Graset al. 107th AACR Annual Meeting, 2016, New Orleans, United States Communication dans un congrès hal-02615962v1
Assessment of the diffusion coefficient of nanocarriers with the fluorescence recovery technique in gastrointestinal mucus Alison Dénarnaud,Jérémie Riou,Rodolphe Perrot,Emilie Roger,Frédéric Lagarceet al. Crossing Biological Barriers - Advances in Nanocarriers Design for Targeted Drug Delivery, 2015, Dresde, Germany Communication dans un congrès hal-02615956v1

Brevet (3)

Formulation de nanocapsules lipidiques par procédé continu d’inversion de phase en concentration Brice Calvignac,Florian Fouchet,Jean-Christophe Gimel,Emilie Roger,Nicolas Rolleyet al. France, N° de brevet: WO2021/014109. 2020 Brevet hal-03133816v1
Formulation de nanocapsules lipidiques par procédé continu d’inversion de phase en concentration Brice Calvignac,Florian Fouchet,Jean-Christophe Gimel,Emilie Roger,Nicolas Rolleyet al. France, N° de brevet: FR30990669. 2019 Brevet hal-03133819v1
Nanocapsules lipidiques, procédé de préparation et utilisation comme médicament Emilie Roger,Frédéric Lagarce,Jean-Pierre Benoît France, N° de brevet: Non spécifié. 2011 Brevet hal-03180820v1

Chapitre d'ouvrage (1)

Transport of therapeutics across intestinal epithelium Frédéric Lagarce,Emilie Roger,Sylvia Muro Drug delivery across physiological barriers, CRC Press, pp.181-208, 2016, 978-981-4669-41-2. ⟨10.1201/b19907-10⟩ Chapitre d'ouvrage hal-01393795v1