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Emmanuel Flahaut

CV de Emmanuel Flahaut
23
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Identifiants chercheurs

Présentation

**University cursus** 1993 – 1995: *Engineering degree at ENSEEG,* Specialisation in Process Engineering and Electrochemistry National Polytechnical Institute of Grenoble 1994 – 1995: *Research Master in Electrochemistry,* University Joseph Fourier, Grenoble (ranked 1st) 1996 – 1999: *PhD in Materials Science,* University Paul Sabatier, Toulouse, France 2000 – 2001: *Post-doctoral research fellow at Oxford University (UK)* *(French ministry of defence grant)* Inorganic Chemistry Laboratory 2001 – *CNRS researcher CNRS* 2007 "*Habilitation à Diriger des Recherches"*, University Paul Sabatier, Toulouse 2010 – *CNRS Research director (Senior Researcher)* **Research activity:** **Carbon nanotubes, graphene and related materials: synthesis, functionalisation, and (biomedical) applications** Pioneering work in the field of synthesis of double-walled carbon nanotubes (DWNT). Development of biomedical applications des CNTs, after investigation of both their potential toxicity / environmental impact. Application fields range from nanocomposites materials to energy, photonics and nanoelectronics. Activity at the interface between on one side chemistry (purification, surface functionalisation including the grafting of dyes or bioactive molecules) and biology on the other side, which gives me a unique position in the field of nanocarbons and allowed me to acquire an international recognition of my work. **PhD students** (as director / co-director): 17 defended, 4 in progress. **Research funding**: &gt; 1.8 M€ obtained to date to fund my research projects **Administrative duties, Prizes and awards, Publications &amp; Communications** \- **Group leader** (Carbon nanotubes et nanocomposites team, CIRIMAT) (2018-) <a name="_Hlk30025380"></a>- Expert (<a name="_Hlk30027812"></a>Observatory of Micro &amp; Nano Technologies), group "effects of nanomaterials and nanoparticles on health and the environment" from 2007 to 2017. [**Expert at ANSES**](https://www.anses.fr/en/content/emmanuel-flahaut) (French National Agency for Food, Environmental and Occupational Health &amp; Safety): (a) Member of [Comité d'Experts Spécialisé](https://www.anses.fr/fr/content/evaluation-des-risques-li%C3%A9s-aux-agents-physiques-aux-nouvelles-technologies-et-aux-grands) "Physical agents, new technologies and major developments" (since 2008); occasional expert for [AFSSAPS](http://ansm.sante.fr/Mediatheque/Publications/Information-in-English) (French National Agency for medicines and health products) (b) Member of workgroup "Human health risk assessment for nanomaterials" (2011 - 2014) (c) Member of workgroup ["Nanomaterials: Health, Food, Environment, Workplace"](https://www.anses.fr/fr/content/nanomat%C3%A9riaux-et-sant%C3%A9-alimentation-environnement-travail) (2012-2015). In particular, work on the French Mandatory declaration of nanoscale substances, [R-Nano](https://www.r-nano.fr/). (d) **Vice president** of the workgroup on "nanoparticles and food" (since 2017) (e) Member of the Evaluation Commission for research projects of the "National Research Programme on Environment / occupational health (PNR-EST) (2014-2018). \- Member of workgroup "labelling/restriction of products containing nanomaterials", DGPR, Ministry of Ecology (2015) \- Expert for the [French High Council of Public Health](http://www.hcsp.fr/) (workgroup on Nano TiO2; 2017 – 2018; 2019). \- Member of the Scientific Council of the epidemiologic study [EpiNano](http://invs.santepubliquefrance.fr/Dossiers-thematiques/Travail-et-sante/EpiNano) (Public Health France) since 2018. \- Regular **Expert for the European** **Commission** (FP7-NMP, ERC) and many other international institutions. \- **Editor of** [***Synthetic Metals***](https://www.journals.elsevier.com/synthetic-metals/editorial-board) (Elsevier) since 2016; Co-editor of the [Encyclopaedia of Nanotechnology, B. Bhushan, Editor (First Ed., 2008)](http://www.springer.com/materials/nanotechnology/book/978-90-481-9750-7). Editorial board of [Springer Nature Appl. Sci](https://www.springer.com/engineering/journal/42452?detailsPage=editorialBoard), [Chem. Phys. Chem](https://onlinelibrary.wiley.com/journal/14397641)., [Frontiers in Materials](https://www.frontiersin.org/journals/materials/sections/carbon-based-materials#editorial-board), [Part. Sci. Technol.](http://www.tandfonline.com/toc/upst20/current#.VNU08i7FOzU) <a name="_Hlk30025914"></a>**-** [***Brian Kelly*** **award**](http://www.rsc.org/Membership/Networking/InterestGroups/britishcarbon/Awards.asp) **- British Carbon Group (2006)** **-** [***Jean Rist*** **medal**](https://sf2m.fr/medailles/15-medaille-jean-rist/) **– French Society of Metallurgy and Materials (2007)** **- *Paul Sabatier* award from the Académie des Sciences, Inscriptions et Belles Lettres de Toulouse (2007)** **-** [**INP'Innov**](http://www.cnrs.fr/dire/actualites/2013/juillet/nautile-280613.htm) **award (National Polytechnical Institute of Toulouse, 2011), for the creation of the joint laboratory Nautile** **-** [**Junior "Distinguished Member" of the French Chemical Society**](http://www.societechimiquedefrance.fr/Membres-distingues-juniors-30.html) **(2014)** **-** [**"Senior researcher" award from the Physical Chemistry Division**](http://www.societechimiquedefrance.fr/Laureats-898.html) **(French Chemical Soc. and French Physical Soc.) (2016)** **- "Scientific excellence" awards (PES) (2010-2018)** **-** [**Fellow of the European Academy of Sciences**](https://www.eurasc.org/user/753/emmanuel-flahaut) **(EurASc) (2020)**

Publications

759623
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Exposure of Midge Larvae (Chironomus riparius) to Graphene Oxide Leads to Development Alterations

Lauris Evariste , Laura Lagier , Chloé Chary , Antoine Mottier , Stéphanie Cadarsi
Toxics, 2022, 10 (10), pp.588. ⟨10.3390/toxics10100588⟩
Article dans une revue hal-03843233v1
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Ecotoxicological assessment of commercial boron nitride nanotubes toward Xenopus laevis tadpoles and host-associated gut microbiota

Lauris Evariste , Emmanuel Flahaut , Clément Baratange , Maialen Barret , Florence Mouchet
Nanotoxicology, 2021, 15 (1), pp.1-17. ⟨10.1080/17435390.2020.1839137⟩
Article dans une revue hal-03170407v1
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Graphene oxide and reduced graphene oxide promote the effects of exogenous T3 thyroid hormone in the amphibian Xenopus laevis

Lauris Evariste , Antoine Mottier , Eric Pinelli , Emmanuel Flahaut , Laury Gauthier
Chemosphere, 2021, 281, pp.130901. ⟨10.1016/j.chemosphere.2021.130901⟩
Article dans une revue hal-03274948v1
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Graphene-Based Nanomaterials Modulate Internal Biofilm Interactions and Microbial Diversity

Lauris Evariste , Paul Braylé , Florence Mouchet , Jérôme Silvestre , Laury Gauthier
Frontiers in Microbiology, 2021, 12, pp.623853. ⟨10.3389/fmicb.2021.623853⟩
Article dans une revue hal-03209487v1
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Transcriptomic response of the benthic freshwater diatom Nitzschia palea exposed to Few Layer Graphene

Marion Garacci , Maialen Barret , Clément Folgoas , Emmanuel Flahaut , George Chimowa
Environmental science‎.Nano, 2019, 6 (5), pp.1363-1381. ⟨10.1039/C8EN00987B⟩
Article dans une revue hal-02160439v1
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Thermal Reduction of Graphene Oxide Mitigates Its In Vivo Genotoxicity Toward Xenopus laevis Tadpoles

Lauris Evariste , Laura Lagier , Patrice Gonzalez , Antoine Mottier , Florence Mouchet
Nanomaterials, 2019, 9 (4), pp.584. ⟨10.3390/nano9040584⟩
Article dans une revue hal-02095596v1
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Few Layer Graphene sticking by biofilm of freshwater diatom Nitzschia palea as a mitigation to its ecotoxicity

Marion Garacci , Maialen Barret , Florence Mouchet , Cyril Sarrieu , Pierre Lonchambon
Carbon, 2017, vol. 113, pp. 139-150. ⟨10.1016/j.carbon.2016.11.033⟩
Article dans une revue hal-01557929v1
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Environmental impact of engineered carbon nanoparticles: from releases to effects on the aquatic biota

Antoine Mottier , Florence Mouchet , Eric Pinelli , Laury Gauthier , Emmanuel Flahaut
Current Opinion in Biotechnology, 2017, vol. 46, pp. 1-6. ⟨10.1016/j.copbio.2016.11.024⟩
Article dans une revue hal-02442144v1
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Surface area of carbon-based nanoparticles prevails on dispersion for growth inhibition in amphibians

Laura Lagier , Florence Mouchet , Christophe Laplanche , Antoine Mottier , Stéphanie Cadarsi
Carbon, 2017, vol. 119, pp. 72-81. ⟨10.1016/j.carbon.2017.04.016⟩
Article dans une revue hal-01578367v1
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International standardized procedures forin vivo evaluation of multi-walled carbon nanotube toxicity in water

Florence Mouchet , Christian Gancet , Emmanuel Flahaut , Eric Pinelli , Jean–charles Boutonnet
Toxicological and Environmental Chemistry, 2016, vol. 98 (n° 8), pp. 829-847. ⟨10.1080/02772248.2015.1133818⟩
Article dans une revue hal-01475094v1
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Examining the impact of multi-layer graphene using cellular and amphibian models

Laura Muzi , Florence Mouchet , Stéphanie Cadarsi , Izabela Janowska , Julie Russier
2D Materials, 2016, vol. 3 (n° 2), pp. 025009. ⟨10.1088/2053-1583/3/2/025009⟩
Article dans une revue hal-01462915v1
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Surface Area of Carbon Nanoparticles: A Dose Metric for a More Realistic Ecotoxicological Assessment

Antoine Mottier , Florence Mouchet , Christophe Laplanche , Stéphanie Cadarsi , Laura Lagier
Nano Letters, 2016, 16 (6), pp.3514-3518. ⟨10.1021/acs.nanolett.6b00348⟩
Article dans une revue hal-01346283v1
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Double walled carbon nanotubes promote the overproduction of extracellular protein-like polymers in Nitzschia palea: An adhesive response for an adaptive issue

Laurent Verneuil , Jérôme Silvestre , Irina Randrianjatovo , Claire-Emmanuelle Marcato-Romain , Elisabeth Girbal-Neuhauser
Carbon, 2015, vol. 88, pp. 113-125. ⟨10.1016/j.carbon.2015.02.053⟩
Article dans une revue hal-01472904v1
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Multi-walled carbon nanotubes, natural organic matter, and the benthic diatom Nitzschia palea: “A sticky story”

Laurent Verneuil , Jérôme Silvestre , Florence Mouchet , Emmanuel Flahaut , Jean-Charles Boutonnet
Nanotoxicology, 2015, vol. 9 (n° 2), pp. 219-229. ⟨10.3109/17435390.2014.918202⟩
Article dans une revue hal-01475246v1
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Short term exposure to multi-walled carbon nanotubes induce oxidative stress and DNA damage in Xenopus laevis tadpoles

Rayenne Saria , Florence Mouchet , Annie Perrault , Emmanuel Flahaut , Christophe Laplanche
Ecotoxicology and Environmental Safety, 2014, 107, pp.22-29. ⟨10.1016/j.ecoenv.2014.05.010⟩
Article dans une revue hal-01963106v1
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Biocompatible polymer-assisted dispersion of multi walled carbon nanotubes in water, application to the investigation of their ecotoxicity using Xenopus laevis amphibian larvae

Floriane Bourdiol , Florence Mouchet , Annie Perrault , Isabelle Fourquaux , Lucien Datas
Carbon, 2013, 54, pp.175-191. ⟨10.1016/j.carbon.2012.11.024⟩
Article dans une revue hal-03526175v1
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Carbon nanotube ecotoxicity in amphibians: assessment of ultiwalled carbon nanotubes and comparison with double-walled carbon nanotubes

Florence Mouchet , Perine Landois , Pascal Puech , Eric Pinelli , Emmanuel Flahaut
Nanomedicine, 2010, 5 (6), pp.963-974. ⟨10.2217/nnm.10.60⟩
Article dans une revue hal-01339444v1

Écotoxicité des nanotubes de carbone dans l’environnement : contexte et état de l’art

Florence Mouchet , Perine Landois , Emmanuel Flahaut , Eric Pinelli , Laury Gauthier
Environnement, Risques & Santé, 2009, 8 (1), pp.47. ⟨10.1684/ers.2009.0215⟩
Article dans une revue hal-01339346v1
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International amphibian micronucleus standardized procedure (ISO 21427-1) for in vivo evaluation of double-walled carbon nanotubes toxicity and genotoxicity in water

Florence Mouchet , Perine Landois , Vitaliy Datsyuk , Pascal Puech , Eric Pinelli
Environmental Toxicology, 2009, 26 (2), pp.136-145. ⟨10.1002/tox.20537⟩
Article dans une revue hal-02051089v1

Characterisation and in vivo ecotoxicity evaluation of double-wall carbon nanotubes in larvae of the amphibian Xenopus laevis

Florence Mouchet , Perine Landois , E. Sarremejean , Guillaume Bernard , Pascal Puech
Aquatic Toxicology, 2008, 87, pp.127-137
Article dans une revue hal-01339334v1
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Characterisation and in vivo ecotoxicity evaluation of double-wall carbon nanotubes in larvae of the amphibian Xenopus laevis

Florence Mouchet , Périne Landois , Elodie Sarremejean , Guillaume Bernard , Pascal Puech
Aquatic Toxicology, 2008, 87 (2), pp.127-137. ⟨10.1016/j.aquatox.2008.01.011⟩
Article dans une revue hal-03591002v1

Assessment of the potential in vivo ecotoxicity of Double-Walled Carbon Nanotubes (DWNTs) in water, using the amphibian Ambystoma mexicanum

Florence Mouchet , Perine Landois , Emmanuel Flahaut , Eric Pinelli , Laury Gauthier
Nanotoxicology, 2007, 1 (2), pp.149-156
Article dans une revue hal-01339325v1
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Assessment of the potential in vivo ecotoxicity of Double-Walled Carbon Nanotubes (DWNTs) in water, using the amphibian Ambystoma mexicanum

Florence Mouchet , Périne Landois , Emmanuel Flahaut , Eric Pinelli , Laury Gauthier
Nanotoxicology, 2007, 1 (2), pp.149-156. ⟨10.1080/17435390701556080⟩
Article dans une revue hal-03592173v1