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emmanuel haffen



professeur des universités - praticien hospitalier, CHU de Besançon Directeur du laboratoire de Recherches Intégratives en Neurosciences et Psychologie Cognitive (UR LINC) de l'Université de Franche-Comté Directeur Adjoint de l'UFR Santé de Besançon Chef du service de Psychiatrie de l'Adulte du CHU de Besançon


Prospective acceptability of digital therapy for major depressive disorder in France: multicentric real-life study

Odile Amiot , Anne Sauvaget , Isabelle Alamome , Samuel Bulteau , Thomas Charpeaud
JMIR Formative Research, 2024, ⟨10.2196/53204⟩
Journal articles hal-04564257v1
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Subjects suffering from bipolar disorder taking lithium are less likely to report physical pain: a FACE-BD study

Nathan Risch , Jonathan Dubois , Bruno Etain , Bruno Aouizerate , Frank Bellivier
European Psychiatry, 2023, 67 (1), pp.e1-e8. ⟨10.1192/j.eurpsy.2023.2476⟩
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Understanding the potential of digital therapies in implementing the standard of care for depression in Europe

Philippe Courtet , Odile Amiot , Enrique Baca-García , Lara Bellardita , Giancarlo Cerveri
European Psychiatry, 2023, European Psychiatry, 66 (1), pp.e82. ⟨10.1192/j.eurpsy.2023.2453⟩
Journal articles hal-04329235v1
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Repeated Anodal Transcranial Direct Current Stimulation (RA-tDCS) over the Left Frontal Lobe Increases Bilateral Hippocampal Cell Proliferation in Young Adult but Not Middle-Aged Female Mice

Stéphanie Dumontoy , Bahrie Ramadan , Pierre-Yves Risold , Solène Pedron , Christophe Houdayer
International Journal of Molecular Sciences, 2023, 24 (10), pp.8750. ⟨10.3390/ijms24108750⟩
Journal articles hal-04186837v1

Transcranial direct current stimulation (tDCS) reduces motivation to drink ethanol and reacquisition of ethanol self-administration in female mice

Solène Pedron , Stéphanie Dumontoy , Maria del Carmen González-Marín , Fabien Coune , Andries van Schuerbeek
Scientific Reports, 2022, 12 (1), pp.198. ⟨10.1038/s41598-021-03940-2⟩
Journal articles hal-03596792v1

Interbrain emotional connection during music performances is driven by physical proximity and individual traits

Thibault Chabin , Damien Gabriel , Alexandre Comte , Emmanuel Haffen , Thierry Moulin
Annals of the New York Academy of Sciences, 2022, 1508 (1), pp.178-195. ⟨10.1111/nyas.14711⟩
Journal articles hal-03600359v1
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Self-Reported Pain and Emotional Reactivity in Bipolar Disorder: A Prospective FACE-BD Study

Nathan Risch , Jonathan Dubois , Katia M’bailara , Irena Cussac , Bruno Etain
Journal of Clinical Medicine, 2022, 11 (3), pp.893. ⟨10.3390/jcm11030893⟩
Journal articles hal-03577632v1
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Violent suicide attempt history in elderly patients with bipolar disorder: The role of sex, abdominal obesity, and verbal memory: Results from the FACE-BD cohort (FondaMental Advanced center of Expertise for Bipolar Disorders)

Aiste Lengvenyte , Bruno Aouizerate , Valerie Aubin , Joséphine Loftus , Emeline Marlinge
Journal of Affective Disorders, 2022, 296, pp.265-276. ⟨10.1016/j.jad.2021.09.097⟩
Journal articles hal-03374307v1

Characterization of depressed bipolar patients with current suicidal ideation

Bénédicte Nobile , Jonathan Dubois , Bruno Aouizerate , Valérie Aubin , Josephine Loftus
Australian and New Zealand Journal of Psychiatry, 2021, 55 (3), pp.289-304. ⟨10.1177/0004867420963744⟩
Journal articles hal-03185089v1
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Pharmacological treatment profiles in the FACE-BD cohort: An unsupervised machine learning study, applied to a nationwide bipolar cohort✰

Sébastien Brodeur , Hugo Terrisse , Arnaud Pouchon , Ophelia Godin , Bruno Aouizerate
Journal of Affective Disorders, 2021, 286, pp.309-319. ⟨10.1016/j.jad.2021.02.036⟩
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Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi‐disciplinary literature review and agenda for future research from the ISBD task force on chronobiology

Cynthia Marie-Claire , Diane Grillault Laroche , Ophélia Godin , Raoul Belzeaux , Katia M'Bailara
Bipolar Disorders, 2021, pp.1-32. ⟨10.1111/bdi.13165⟩
Journal articles hal-03568951v1
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Saccadic Eye Movements in Elderly Depressed Patients With Suicidal Behaviors: An Exploratory Eye-Tracking Study

Yoan Barsznica , Nicolas Noiret , Bérénice Lambert , Julie Monnin , Claire de Pinho
Frontiers in Psychology, 2021, 12, pp.712347. ⟨10.3389/fpsyg.2021.712347⟩
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The course of bipolar disorder as a function of the presence and sequence of onset of comorbid alcohol use disorders in outpatients attending the Fondamental Advanced Centres of Expertise

Romain Icick , Sébastien Gard , Katia M'Bailara , Isabelle Biseul , Ludovic Samalin
Journal of Affective Disorders, 2021, 287, pp.196-203. ⟨10.1016/j.jad.2021.03.041⟩
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Association between anhedonia and suicidal events in patients with mood disorders: A 3‐year prospective study

Déborah Ducasse , Jonathan Dubois , Isabelle Jaussent , Jean‐michel Azorin , Bruno Etain
Depression and Anxiety, 2021, 38 (1), pp.17-27. ⟨10.1002/da.23072⟩
Journal articles hal-03545296v1

Repetitive Transcranial Magnetic Stimulation as an Add-On Treatment for Cognitive Impairment in Alzheimer’s Disease and Its Impact on Self-Rated Quality of Life and Caregiver’s Burden

Juliana Teti Mayer , Caroline Masse , Gilles Chopard , Magali Nicolier , Matthieu Bereau
Brain Sciences, 2021, 11 (6), pp.740. ⟨10.3390/brainsci11060740⟩
Journal articles hal-03630048v1
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Emotional Effects Induced by the Application of a Cosmetic Product: A Real-Time Electrophysiological Evaluation

Damien Gabriel , Emmanuelle Merat , Adeline Jeudy , Sophie Cambos , Thibault Chabin
Applied Sciences, 2021, 11 (11), pp.4766. ⟨10.3390/app11114766⟩
Journal articles hal-03656155v1
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Chronic Exposure to Glucocorticoids Induces Suboptimal Decision-Making in Mice

Lidia Cabeza , Bahrie Ramadan , Julie Giustiniani , Christophe Houdayer , Yann Pellequer
European Neuropsychopharmacology, 2021, 46, pp.56-67. ⟨10.1016/j.euroneuro.2021.01.094⟩
Journal articles hal-03630683v1
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Relationship between childhood physical abuse and clinical severity of treatment-resistant depression in a geriatric population

Antoine Yrondi , Christophe Arbus , Djamila Bennabi , Thierry D’amato , Frank Bellivier
PLoS ONE, 2021, 16 (4), pp.e0250148. ⟨10.1371/journal.pone.0250148⟩
Journal articles hal-03239839v1
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Towards a Functional Neuromarker of Impulsivity: Feedback-Related Brain Potential during Risky Decision-Making Associated with Self-Reported Impulsivity in a Non-Clinical Sample

Juliana Teti Mayer , Charline Compagne , Magali Nicolier , Yohan Grandperrin , Thibault Chabin
Brain Sciences, 2021, 11 (6), pp.671. ⟨10.3390/brainsci11060671⟩
Journal articles hal-03655689v1
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The Anti-inflammatory Effect of the Tricyclic Antidepressant Clomipramine and Its High Penetration in the Brain Might Be Useful to Prevent the Psychiatric Consequences of SARS-CoV-2 Infection

Bénédicte Nobile , M. Durand , Emilie Olié , Sébastien Guillaume , Jean-Pierre Molès
Frontiers in Pharmacology, 2021, 12, pp.615695. ⟨10.3389/fphar.2021.615695⟩
Journal articles hal-03187074v1

Cognitive Impairment in Late-Life Depression: A Comparative Study of Healthy Older People, Late-Life Depression, and Mild Alzheimer's Disease Using Multivariate Base Rates of Low Scores

Caroline Masse , Pierre Vandel , Géraldine Sylvestre , Nicolas Noiret , Djamila Bennabi
Frontiers in Psychology, 2021, 12, ⟨10.3389/fpsyg.2021.724731⟩
Journal articles hal-03516179v1

Validity and Usage of the Seasonal Pattern Assessment Questionnaire (SPAQ) in a French Population of Patients with Depression, Bipolar Disorders and Controls

Eve Reynaud , Fabrice Berna , Emmanuel Haffen , Luisa Weiner , Julia Maruani
Journal of Clinical Medicine, 2021, 10 (9), pp.1897. ⟨10.3390/jcm10091897⟩
Journal articles hal-03658193v1
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Childhood Trauma increases suicidal behaviour in a treatment-resistant depression population: a FACE-DR report

Antoine Yrondi , Guillaume Vaiva , Michel Walter , Thierry D Amato , Frank Bellivier
Journal of Psychiatric Research, 2021, 135, pp.20-27. ⟨10.1016/j.jpsychires.2020.12.055⟩
Journal articles hal-03271134v1

Repetitive Transcranial Magnetic Stimulation as an Add-On Treatment for Cognitive Impairment in Alzheimer’s Disease and Its Impact on Self-Rated Quality of Life and Caregiver’s Burden

Juliana Teti Mayer , Caroline Masse , Gilles Chopard , Magali Nicolier , Matthieu Bereau
Brain Sciences, 2021, 11 (6), pp.740. ⟨10.3390/brainsci11060740⟩
Journal articles hal-03656175v1

Clomipramine Could Be Useful in Preventing Neurological Complications of SARS-CoV-2 Infection

Benedicte Nobile , Mélusine Durand , Emilie Olié , Sebastien Guillaume , Jean-Pierre Molès
Journal of Neuroimmune Pharmacology, 2020, ⟨10.1007/s11481-020-09939-2⟩
Journal articles hal-02890672v1
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Event-Related Potentials (ERP) Indices of Motivation during the Effort Expenditure for Reward Task

Julie Giustiniani , Magali Nicolier , Juliana Teti Mayer , Thibault Chabin , Caroline Masse
Brain Sciences, 2020, 10 (5), pp.283. ⟨10.3390/brainsci10050283⟩
Journal articles hal-03656188v1

Can transcranial direct current stimulation (tDCS) improve impulsivity in healthy and psychiatric adult populations? A systematic review

Juliana Teti Mayer , Gilles Chopard , Magali Nicolier , Damien Gabriel , Caroline Masse
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2020, 98, pp.109814 -. ⟨10.1016/j.pnpbp.2019.109814⟩
Journal articles hal-03488700v1

Influence of Transcranial Direct Current Stimulation on Psychomotor Symptoms in Major Depression

Djamila Bennabi , Nicolas Carvalho , Ambra Bisio , Juliana Teti Mayer , Thierry Pozzo
Brain Sciences, 2020, 10 (11), pp.792. ⟨10.3390/brainsci10110792⟩
Journal articles hal-03655678v1

Comparison of Noninvasive Imagery Methods to Observe Healthy and Degenerated Olfactory Epithelium in Mice for the Early Diagnosis of Neurodegenerative Diseases

Brahim Tamadazte , Adeline Etievant , Julie Monnin , Thomas Lihoreau , Patrick Rougeot
Frontiers in Neuroanatomy, 2020, 14 (4), pp.533-536. ⟨10.3389/fnana.2020.00034⟩
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Treatment-resistant depression in a real-world setting: first interim analysis of characteristics, healthcare resource use, and utility values of the fondaMental cohort

Antoine Yrondi , Djamila Bennabi , Emmanuel Haffen , Delphine Quelard , Ludovic Samalin
Brain Sciences, 2020, 10 (12), pp.1-16. ⟨10.3390/brainsci10120962⟩
Journal articles hal-03177554v1
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Evolution and characteristics of the use of valproate in women of childbearing age with bipolar disorder: Results from the FACE-BD cohort

Ludovic Samalin , Ophélia Godin , Émilie Olié , Bruno Etain , Chantal Henry
Journal of Affective Disorders, 2020, 276, pp.963-969. ⟨10.1016/j.jad.2020.07.078⟩
Journal articles hal-03032308v1

Childhood maltreatment and clinical severity of treatment‐resistant depression in a French cohort of outpatients (FACE‐DR): One‐year follow‐up

Antoine Yrondi , Bruno Aouizerate , Djamila Bennabi , Raphaëlle Richieri , Thierry d'Amato
Depression and Anxiety, 2020, 37 (4), pp.365-374. ⟨10.1002/da.22997⟩
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Modelling decision-making under uncertainty: A direct comparison study between human and mouse gambling data

Lidia Cabeza , Julie Giustiniani , Thibault Chabin , Bahrie Ramadan , Coralie Joucla
European Neuropsychopharmacology, 2020, 31, pp.58 - 68. ⟨10.1016/j.euroneuro.2019.11.005⟩
Journal articles hal-03489863v1

Skin conductance response and emotional response in women with psychogenic non-epileptic seizures

Hugo Herrero , Alexis Tarrada , Emmanuel Haffen , Thibault Mignot , Charlotte Sense
Seizure - European Journal of Epilepsy, 2020, 81, pp.123-131. ⟨10.1016/j.seizure.2020.07.028⟩
Journal articles hal-02931214v1

Prevalence of Metabolic Syndrome and Associated Factors in a Cohort of Individuals With Treatment-Resistant Depression

Ophelia Godin , Djamila Bennabi , Antoine Yrondi , Raphaëlle Richieri , Thierry D’amato
The Journal of clinical psychiatry, 2019, 80 (6), ⟨10.4088/JCP.19m12755⟩
Journal articles hal-02555531v1

Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative

Jan Scott , Diego Hidalgo-Mazzei , Rebecca Strawbridge , Allan H. Young , Matthieu Resche-Rigon
International Journal of Bipolar Disorders, 2019, 7 (1), pp.20. ⟨10.1186/s40345-019-0156-x⟩
Journal articles cea-02316734v1
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Troubles de l’humeur : quand recourir à la stimulation magnétique transcrânienne ?

Samuel Bulteau , Charline Guirette , Jérôme Brunelin , Emmanuel Poulet , Benoit Trojak
La Presse Médicale, 2019, 48 (6), pp.625-646. ⟨10.1016/j.lpm.2019.01.012⟩
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Effects of High Frequency Repetitive Transcranial Magnetic Stimulation (HF-rTMS) on Delay Discounting in Major Depressive Disorder: An Open-Label Uncontrolled Pilot Study

Juliana Teti Mayer , Magali Nicolier , Gregory Tio , Stephane Mouchabac , Emmanuel Haffen
Brain Sciences, 2019, 9 (9), pp.230. ⟨10.3390/brainsci9090230⟩
Journal articles hal-02315124v1

Motor Resonance Mechanisms during Action Imitation in Depression

Djamila Bennabi , Nicolas Carvalho , Ambra Bisio , Emmanuel Haffen , Thierry Pozzo
Cognitive Neuropsychiatry, 2018, 08 (05), pp.1503-1512
Journal articles hal-01940191v1
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In Vivo Inspection of the Olfactory Epithelium: Feasibility of Robotized Optical Biopsy

Cédric Girerd , Thomas Lihoreau , Kanty Rabenorosoa , Brahim Tamadazte , Mourad Benassarou
Annals of Biomedical Engineering, 2018, 46 (11), pp.1951-1961. ⟨10.1007/s10439-018-2076-9⟩
Journal articles hal-02126171v1

Early weight gain predicts later metabolic syndrome in depressed patients treated with antidepressants: Findings from the METADAP cohort

Khalil El Asmar , Bruno Fève , Romain Colle , Séverine Trabado , Céline Verstuyft
Journal of Psychiatric Research, 2018, 107, pp.120-127. ⟨10.1016/j.jpsychires.2018.10.021⟩
Journal articles hal-03658177v1

Evidence for a neural signature of musical preference during silence

Coralie Joucla , Magali Nicolier , Julie Giustiniani , Gaelle Brunotte , Nicolas Noiret
International Journal of Psychophysiology, 2018, 125, pp.50-56. ⟨10.1016/j.ijpsycho.2018.02.007⟩
Journal articles hal-02439752v1

Glycogen synthase kinase-3β genetic polymorphisms and insomnia in depressed patients: A prospective study

Jean-François Costemale-Lacoste , Romain Colle , Séverine Martin , Khalil El Asmar , Emanuel Loeb
Journal of Affective Disorders, 2018, 240, pp.230-236. ⟨10.1016/j.jad.2018.07.062⟩
Journal articles hal-03658170v1
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Assessment of Translocator Protein Density, as Marker of Neuroinflammation, in Major Depressive Disorder: A Pilot, Multicenter, Comparative, Controlled, Brain PET Study (INFLADEP Study)

Antoine Yrondi , Bruno Aouizerate , Wissam El-Hage , Fanny Moliere , Claire Thalamas
Frontiers in Psychiatry, 2018, 9, pp.326. ⟨10.3389/fpsyt.2018.00326⟩
Journal articles hal-01856019v1

Early weight gain predicts later weight gain in depressed patients treated with antidepressants: Findings from the METADAP cohort

Khalil El Asmar , Bruno Fève , Romain Colle , Florence Gressier , Albane Vievard
Journal of Affective Disorders, 2018, 241, pp.22-28. ⟨10.1016/j.jad.2018.07.059⟩
Journal articles hal-03658179v1
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Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study)

Célia Lloret-Linares , Youssef Daali , Sylvie Chevret , Isabelle Nieto , Fanny Molière
BMC Pharmacology and Toxicology, 2017, 18 (1), pp.70. ⟨10.1186/s40360-017-0173-2⟩
Journal articles hal-01696753v1

The antidepressant-like effect of tDCS in mice: A behavioral and neurobiological characterization

Tanat Peanlikhit , Vincent van Waes , Solène Pedron , P. Y. Risold , Emmanuel Haffen
Brain Stimulation, 2017, 10 (4), pp.748-756. ⟨10.1016/j.brs.2017.03.012⟩
Journal articles hal-03600363v1

Serotonin transporter gene expression predicts the worsening of suicidal ideation and suicide attempts along a long-term follow-up of a Major Depressive Episode

Julia-Lou Consoloni , El Chérif Ibrahim , Marie-Noëlle Lefebvre , Xavier Zendjidjian , Emilie Olié
European Neuropsychopharmacology, 2017, ⟨10.1016/j.euroneuro.2017.12.015⟩
Journal articles hal-01696652v1
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Significant Need for a French Network of Expert Centers Enabling a Better Characterization and Management of Treatment-Resistant Depression (Fondation FondaMental)

Antoine Yrondi , Djamila Bennabi , Emmanuel Haffen , Marion Garnier , Frank Bellivier
Frontiers in Psychiatry, 2017, 8, ⟨10.3389/fpsyt.2017.00244⟩
Journal articles hal-02514024v1

Severe insomnia is associated with hypertriglyceridemia in women with major depression treated in psychiatry settings

Jean-François Costemale-Lacoste , Séverine Trabado , Céline Verstuyft , Khalil El Asmar , Florence Butlen-Ducuing
Journal of Affective Disorders, 2017, 217, pp.159 - 162. ⟨10.1016/j.jad.2017.04.011⟩
Journal articles hal-01569113v1

A Bayesian framework systematic review and meta-analysis of anesthetic ă agents effectiveness/tolerability profile in electroconvulsive therapy ă for major depression

Djamila Bennabi , Emmanuel Haffen , Lore Brunel , Jean-Arthur Micoulaud-Franchi , Anderson Loundou
Scientific Reports, inPress, 6 (19847), ⟨10.1038/srep19847⟩
Journal articles hal-01482509v1

Dépression résistante : les autres stratégies thérapeutiques

Ghassen Saba , Isabel Nieto , Rémy Bation , Najib Allaïli , Djamila Bennabi
La Presse Médicale, 2016, 45 (3), pp.350 - 359. ⟨10.1016/j.lpm.2016.02.005⟩
Journal articles hal-01872719v1

Resistant depression : Switching and combining strategies of ă antidepressant medications

Thomas Charpeaud , Fanny Moliere , Maxime Bubrovszky , Frederic Haesebaert , Najib Allaïli
La Presse Médicale, 2016, 45 (3), pp.329-337. ⟨10.1016/j.lpm.2016.02.003⟩
Journal articles hal-01482632v1

Quelle définition pour la dépression résistante ?

Jérôme Holtzmann , Raphaëlle Richieri , Ghassen Saba , Najib Allaïli , Rémy Bation
La Presse Médicale, 2016, 45 (3), pp.323 - 328. ⟨10.1016/j.lpm.2016.02.002⟩
Journal articles hal-01872821v1

Resistant depression : potentiation strategies

Olivier Doumy , Djamila Bennabi , Wissam El-Hage , Najib Allaïli , Remy Bation
La Presse Médicale, 2016, 45 (3), pp.338-349. ⟨10.1016/j.lpm.2016.02.004⟩
Journal articles hal-01482633v1

Mast cells' involvement in inflammation pathways linked to depression: evidence in mastocytosis

Sophie Georgin-Lavialle , Daniela Silva Moura , Alexandre Salvador , Jean-Christophe Chauvet-Gélinier , Jean-Marie Launay
Molecular Psychiatry, 2016, 21 (11), pp.1511 - 1516. ⟨10.1038/mp.2015.216⟩
Journal articles hal-01548862v1

Google Trends ® : Ready for real-time suicide prevention or just a Zeta-Jones effect? An exploratory study

Guillaume Fond , Alexandru Gaman , Lore Brunel , Emmanuel Haffen , Pierre-Michel Llorca
Psychiatry Research, 2015, 228 (3), pp.913-917. ⟨10.1016/j.psychres.2015.04.022⟩
Journal articles hal-02173616v1

Motor imagery in unipolar major depression

Djamila Bennabi , Julie Monnin , Emmanuel Haffen , Nicolas Carvalho , Pierre Vandel
Frontiers in Behavioral Neuroscience, 2014, 8, pp.413. ⟨10.3389/fnbeh.2014.00413⟩
Journal articles hal-01159606v1

The Efficacy and Safety of Low Frequency Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Depression: The Results From a Large Multicenter French RCT

Marie Izaute , Jérôme Brunelin , Isabelle Jalenques , Benoit Trojak , Jérôme Attal
Brain Stimulation, 2014, 7 (6), pp.855-863. ⟨10.1016/j.brs.2014.07.040⟩
Journal articles hal-02165793v1

Visual scanning behavior during processing of emotional faces in older adults with major depression

Nicolas Noiret , Nicolas Carvalho , Éric Laurent , Lauriane Vulliez , Djamila Bennabi
Aging and Mental Health, 2014, 19 (3), pp.264-273. ⟨10.1080/13607863.2014.926473⟩
Journal articles hal-02437324v1
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Massively multiplayer online role-playing games: comparing characteristics of addict vs non-addict online recruited gamers in a French adult population.

Sophia Achab , Magali Nicolier , Frédéric Mauny , Julie Monnin , Benoit Trojak
BMC Psychiatry, 2011, 11 (1), pp.144. ⟨10.1186/1471-244X-11-144⟩
Journal articles inserm-00626205v1

[Pharmacogenetics of depression in elderly patients]

Julie Monnin , Emmanuel Haffen , Daniel Sechter , Pierre Vandel
Psychologie & neuropsychiatrie du vieillissement, 2009, 7 (1), pp.43-55. ⟨10.1684/pnv.2009.0157⟩
Journal articles hal-00493439v1

Does hospitalisation affect hypnotic and anxiolytic drug prescribing?

Philippe Fagnoni , Samuel Limat , Emmanuel Haffen , Thierry Henon , Micheline Jacquet
Pharmacy World & Science, 2007, 29 (6), pp.611-8. ⟨10.1007/s11096-007-9097-z⟩
Journal articles hal-00493432v1