Emmanuel Brouillet

Publications

Article dans une revue (73)

Loss of the neuronal kinase DCLK3 leads to anxiety-like behaviour and memory deficits Lucie de Longprez,Marie-Claude Gaillard,Charles Decraene,Jean-Baptiste Perot,Celine Keimeet al. Brain - A Journal of Neurology , 2025, ⟨10.1093/brain/awaf042⟩ Article dans une revue hal-04938607v1
Longitudinal MRI and 1H-MRS study of SCA7 mouse forebrain reveals progressive multiregional atrophy and early brain metabolite changes indicating early neuronal and glial dysfunction Jean-Baptiste Pérot,Anna Niewiadomska-Cimicka,Emmanuel Brouillet,Yvon Trottier,Julien Flament PLoS ONE, 2024, 19 (1), pp.e0296790. ⟨10.1371/journal.pone.0296790⟩ Article dans une revue hal-04400325v1
Reactive astrocytes promote proteostasis in Huntington’s disease through the JAK2-STAT3 pathway Laurene Abjean,Lucile Ben Haim,Miriam Riquelme-Perez,Pauline Gipchtein,Céline Derboiset al. Brain - A Journal of Neurology , 2023, 146 (1), pp.149-166. ⟨10.1093/brain/awac068⟩ Article dans une revue hal-04312671v1
Development of an AAV-based model of tauopathy targeting retinal ganglion cells and the mouse visual pathway to study the role of microglia in Tau pathology Charlotte Duwat,Pauline Léal,Audrey Vautheny,Gwennaëlle Aurégan,Charlène Joséphineet al. Neurobiology of Disease, 2023, 181, pp.106116. ⟨10.1016/j.nbd.2023.106116⟩ Article dans une revue hal-04312700v1
Extreme conservation of the poly-glutamine tract in huntingtin is related to neurodevelopmental functions: the “better” may become the “enemy of the good” in the course of evolution Emmanuel Brouillet Cell Death and Differentiation, 2022, 29 (2), pp.266-268. ⟨10.1038/s41418-021-00927-4⟩ Article dans une revue hal-04312713v1
Longitudinal multimodal MRI characterization of a knock-in mouse model of Huntington’s disease reveals early gray and white matter alterations Jean-Baptiste Pérot,Marina Célestine,Marco Palombo,Marc Dhenain,Sandrine Humbertet al. Human Molecular Genetics, 2022, ⟨10.1093/hmg/ddac036⟩ Article dans une revue hal-03787296v1
Longitudinal multimodal MRI characterization of a knock-in mouse model of Huntington’s disease reveals early gray and white matter alterations Jean-Baptiste Pérot,Marina Célestine,Marco Palombo,Marc Dhenain,Sandrine Humbertet al. Human Molecular Genetics, 2022, 31 (21), pp.3581-3596. ⟨10.1093/hmg/ddac036⟩ Article dans une revue hal-04312686v1
Altered activity-regulated H3K9 acetylation at TGF-beta signaling genes during egocentric memory in Huntington’s disease Rafael Alcalá-Vida,Caroline Lotz,Baptiste Brulé,Jonathan Seguin,Charles Decraeneet al. Progress in Neurobiology, 2022, 219, pp.102363. ⟨10.1016/j.pneurobio.2022.102363⟩ Article dans une revue hal-03850389v1
Precision machine learning to understand micro-RNA regulation in neurodegenerative diseases Lucile Mégret,Cloé Mendoza,Maialen Arrieta Lobo,Emmanuel Brouillet,Thi-Thanh-Yen Nguyenet al. Frontiers in Molecular Neuroscience, 2022, 15, pp.914830. ⟨10.3389/fnmol.2022.914830⟩ Article dans une revue hal-04312610v1
Time-Course of Alterations in the Endocannabinoid System after Viral-Mediated Overexpression of α-Synuclein in the Rat Brain Rachel Kelly,Alexis-Pierre Bemelmans,Charlène Joséphine,Emmanuel Brouillet,Declan P Mckernanet al. Molecules, 2022, 27 (2), pp.507. ⟨10.3390/molecules27020507⟩ Article dans une revue (data paper) hal-04419946v1
Longitudinal multimodal MRI characterization of a knock-in mouse model of Huntington’s disease reveals early gray and white matter alterations Jean-Baptiste Pérot,Marina Célestine,Marco Palombo,Marc Dhenain,Sandrine Humbertet al. Human Molecular Genetics, 2022, 31 (21), pp.3581-3596. ⟨10.1093/hmg/ddac036⟩ Article dans une revue hal-04246453v1
Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway Laurene Abjean,Lucile Ben Haim,Miriam Riquelme-Perez,Pauline Gipchtein,Céline Derboiset al. Brain - A Journal of Neurology , 2022, ⟨10.1093/brain/awac068/6550082⟩ Article dans une revue cea-03872742v1
THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency Audrey Vautheny,Charlotte Duwat,Gwennaëlle Aurégan,Charlène Joséphine,Anne-Sophie Hérardet al. Neurobiology of Disease, 2021, 155, pp.105398. ⟨10.1016/j.nbd.2021.105398⟩ Article dans une revue inserm-03366724v1
SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2 Anna Niewiadomska-Cimicka,Frédéric Doussau,Jean-Baptiste Perot,Michel Roux,Celine Keimeet al. Journal of Neuroscience, 2021, 41 (22), pp.4910-4936. ⟨10.1523/JNEUROSCI.1882-20.2021⟩ Article dans une revue hal-03378998v1
Broad Influence of Mutant Ataxin-3 on the Proteome of the Adult Brain, Young Neurons, and Axons Reveals Central Molecular Processes and Biomarkers in SCA3/MJD Using Knock-In Mouse Model Kalina Wiatr,Łukasz Marczak,Jean-Baptiste Pérot,Emmanuel Brouillet,Julien Flamentet al. Frontiers in Molecular Neuroscience, 2021, 14, ⟨10.3389/fnmol.2021.658339⟩ Article dans une revue hal-04246406v1
The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models Rachel Kelly,Andrew G Cairns,Jörgen Ådén,Fredrik Almqvist,Alexis-Pierre Bemelmanset al. Biomolecules, 2021, 11 (11), pp.1685. ⟨10.3390/biom11111685⟩ Article dans une revue hal-04444836v1
Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state Anastasie Maté de Gérando,Marie D’orange,Emma Augustin,Charlène Joséphine,Gwénaelle Auréganet al. Brain - A Journal of Neurology , 2021, 12 (4), pp.1167-1182. ⟨10.1093/brain/awab011⟩ Article dans une revue inserm-03385148v1
Complete spatial characterisation of N-glycosylation upon striatal neuroinflammation in the rodent brain Ana Lúcia Rebelo,Francesco Gubinelli,Pauline Roost,Caroline Jan,Emmanuel Brouilletet al. Journal of Neuroinflammation, 2021, 18 (1), pp.116. ⟨10.1186/s12974-021-02163-6⟩ Article dans une revue cea-04470933v1
The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo Noémie Cresto,Camille Gardier,Marie-Claude Gaillard,Francesco Gubinelli,Pauline Roostet al. International Journal of Molecular Sciences, 2021, 22 (13), pp.6760. ⟨10.3390/ijms22136760⟩ Article dans une revue hal-03452142v1
The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo Noémie Cresto,Marie-Claude Gaillard,Camille Gardier,Francesco Gubinelli,Elsa Diguetet al. Neurobiology of Disease, 2020, 134, pp. 104614. ⟨10.1016/j.nbd.2019.104614⟩ Article dans une revue hal-04476988v1
Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease. Océane Guillemaud,Kelly Ceyzériat,Thomas Saint-Georges,Karine Cambon,Fanny Petitet al. Neurobiology of Aging, 2020, 90, pp.135-146. ⟨10.1016/j.neurobiolaging.2020.02.010⟩ Article dans une revue cea-03023752v1
The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo Noémie Cresto,Marie-Claude Gaillard,Camille Gardier,Francesco Gubinelli,Elsa Diguetet al. Neurobiology of Disease, 2020, 134, pp.104614. ⟨10.1016/j.nbd.2019.104614⟩ Article dans une revue hal-03043360v1
Complementarity of gluCEST and $^1$H‐MRS for the study of mouse models of Huntington's disease Jérémy Pépin,Lucie de Longprez,Fabrice Trovero,Emmanuel Brouillet,Julien Valetteet al. NMR in Biomedicine, 2020, 33 (7), pp.e4301. ⟨10.1002/nbm.4301⟩ Article dans une revue hal-03043297v1
Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease Juliette Le Douce,Marianne Maugard,Julien Veran,Marco Matos,Pierrick Jégoet al. Cell Metabolism, 2020, 31 (3), pp.503-517.e8. ⟨10.1016/j.cmet.2020.02.004⟩ Article dans une revue hal-02989009v2
Iatrogenic transmission of Alzheimer's disease: Evidence based on experimental inoculation of Alzheimer's brains into a primate Marc Dhenain,Suzanne Lam,Charlotte Gary,Anne‐sophie Herard,James Kochet al. Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2020, 16 (S2), ⟨10.1002/alz.042957⟩ Article dans une revue hal-03453400v1
Encephalopathy induced by Alzheimer brain inoculation in a non-human primate Charlotte Gary,Suzanne Lam,Anne-Sophie Herard,James E Koch,Fanny Petitet al. Acta Neuropathologica Communications, 2019, 7 (1), ⟨10.1186/s40478-019-0771-x⟩ Article dans une revue hal-02391937v1
What is gained or ‘lost in translation’ in Huntington’s disease Emmanuel Brouillet,Karine Merienne Brain - A Journal of Neurology , 2019, 142 (10), pp.2900-2902. ⟨10.1093/brain/awz274⟩ Article dans une revue hal-03058364v1
Diffusion-weighted magnetic resonance spectroscopy enables cell-specific monitoring of astrocyte reactivity $in\ vivo$ Clémence Ligneul,Marco Palombo,Edwin Hernández-Garzón,Maria-Angeles Carrillo-de Sauvage,Julien Flamentet al. NeuroImage, 2019, 191, pp.457-469. ⟨10.1016/j.neuroimage.2019.02.046⟩ Article dans une revue cea-02155405v1
Optogenetic Tractography for anatomo-functional characterization of cortico-subcortical neural circuits in non-human primates S Senova,C Poupon,J Dauguet,H J Stewart,G P Duguéet al. Scientific Reports, 2018, 8 (1), pp.3362. ⟨10.1038/s41598-018-21486-8⟩ Article dans une revue hal-04474162v1
The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin Laurie Galvan,Laetitia Francelle,Marie-Claude Gaillard,Lucie de Longprez,Maria-Angeles Carrillo-de Sauvageet al. Brain - A Journal of Neurology , 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩ Article dans une revue hal-02074093v1
The unlikely partnership between LRRK 2 and α‐synuclein in Parkinson's disease Noémie Cresto,Camille Gardier,Francesco Gubinelli,Marie‐claude Gaillard,Géraldine Liotet al. European Journal of Neuroscience, 2018, 49 (3), pp.339-363. ⟨10.1111/ejn.14182⟩ Article dans une revue hal-04476987v1
Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease Kelly Ceyzériat,Lucile Ben Haim,Audrey Denizot,Dylan Pommier,Marco Matoset al. Acta Neuropathologica Communications, 2018, 6 (1), pp.1047. ⟨10.1186/s40478-018-0606-1⟩ Article dans une revue hal-02074082v1
Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat Marie D’orange,Gwenaëlle Auregan,Dimitri Cheramy,Mylène Gaudin-Guérif,Sarah Liegeret al. Brain - A Journal of Neurology , 2018, 141 (2), pp.535-549. ⟨10.1093/brain/awx342⟩ Article dans une revue cea-02074052v1
Energy defects in Huntington's disease: Why “in vivo” evidence matters Géraldine Liot,Julien Valette,Jérémy Pépin,Julien Flament,Emmanuel Brouillet Biochemical and Biophysical Research Communications, 2017, 483, pp.1084 - 1095. ⟨10.1016/j.bbrc.2016.09.065⟩ Article dans une revue istex cea-01752431v1
Contribution of neuroepigenetics to Huntington’s disease Laetitia Francelle,Caroline Lotz,Tiago Outeiro,Emmanuel Brouillet,Karine Merienne Frontiers in Human Neuroscience, 2017, 11, pp.17. ⟨10.3389/fnhum.2017.00017⟩ Article dans une revue cea-01751739v1
Altered enhancer transcription underlies Huntington’s disease striatal transcriptional signature Stéphanie Le Gras,Céline Keime,Anne Anthony,Caroline Lotz,Lucie de Longprezet al. Scientific Reports, 2017, 7 (Article number: 42875), ⟨10.1038/srep42875⟩ Article dans une revue cea-01751880v1
Coupling of D2R Short but not D2R Long receptor isoform to the Rho/ROCK signaling pathway renders striatal neurons vulnerable to mutant huntingtin Jocelyne Caboche,Galan-Rodriguez Beatriz,Martin Elodie,Emmanuel ; Déglon,Betuing Sandrineet al. European Journal of Neuroscience, 2017, 45 (1), pp.198-206. ⟨10.1111/ejn.13415⟩ Article dans une revue hal-03365878v1
Imaging and spectroscopic approaches to probe brain energy metabolism dysregulation in neurodegenerative diseases Gilles Bonvento,Julien Valette,Julien Flament,Fanny Mochel,Emmanuel Brouillet Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (6), pp.1927-1943. ⟨10.1177/0271678X17697989⟩ Article dans une revue hal-01539753v1
Energy defects in Huntington's disease: Why “in vivo” evidence matters Géraldine Liot,Julien Valette,Jérémy Pépin,Julien Flament,Emmanuel Brouillet Biochemical and Biophysical Research Communications, 2017, 483 (4), pp.1084-1095. ⟨10.1016/j.bbrc.2016.09.065⟩ Article dans une revue istex hal-04476989v1
In vivo imaging of brain glutamate defects in a knock-in mouse model of Huntington's disease Jérémy Pépin,Laetitia Francelle,Maria-Angeles Carrillo-de Sauvage,Lucie de Longprez,Pauline Gipchteinet al. NeuroImage, 2016, 139, pp.53-64. ⟨10.1016/j.neuroimage.2016.06.023⟩ Article dans une revue cea-02397809v1
New paradigm to assess brain cell morphology by diffusion-weighted MR spectroscopy in vivo Marco Palombo,Clémence Ligneul,Chloé Najac,Juliette Le Douce,Julien Flamentet al. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (24), pp.6671-6676. ⟨10.1073/pnas.1504327113⟩ Article dans une revue cea-02155309v1
Evidence for a “metabolically inactive” inorganic phosphate pool in adenosine triphosphate synthase reaction using localized 31P saturation transfer magnetic resonance spectroscopy in the rat brain at 11.7 T Brice Tiret,Emmanuel Brouillet,Julien Valette Journal of Cerebral Blood Flow and Metabolism, 2016, 36 (9), pp.1513-1518. ⟨10.1177/0271678X16657095⟩ Article dans une revue cea-02155315v1
Coupling of D2R Short but not D2R Long receptor isoform to the Rho/ROCK signaling pathway renders striatal neurons vulnerable to mutant huntingtin Beatriz Galan-Rodriguez,Elodie Martin,Emmanuel Brouillet,Nicole Déglon,Sandrine Betuinget al. European Journal of Neuroscience, 2016, pp.198-206 ⟨10.1111/ejn.13415⟩ Article dans une revue hal-01396567v1
Synaptic scaling up in medium spiny neurons of aged BACHD mice: A slow-progression model of Huntington's disease Anne Rocher,Paolo Gubellini,Nicolas Merienne,Lydie Boussicault,Fanny Petitet al. Neurobiology of Disease, 2016, 86, pp.131-139. ⟨10.1016/j.nbd.2015.10.016⟩ Article dans une revue istex hal-03584029v1
Age-associated evolution of plasmatic amyloid in mouse lemur primates: relationship with intracellular amyloid deposition Maggie Roy,Cécile Cardoso,Olène Dorieux,Carole Malgorn,Stéphane Epelbaumet al. Neurobiology of Aging, 2015, 36 (1), pp.149-156. ⟨10.1016/j.neurobiolaging.2014.07.017⟩ Article dans une revue mnhn-02291873v1
The Neuroprotective Agent CNTF Decreases Neuronal Metabolites in the Rat Striatum: An $in\ Vivo$ Multimodal Magnetic Resonance Imaging Study Maria-Angeles Carrillo-de Sauvage,Julien Flament,Yann Bramoullé,Lucile Ben Haim,Martine Guillermieret al. Journal of Cerebral Blood Flow and Metabolism, 2015, 35 (6), pp.917-921. ⟨10.1038/jcbfm.2015.48⟩ Article dans une revue cea-02168367v1
The striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo Laetitia Francelle,Laurie Galvan,Marie-Claude Gaillard,Fanny Petit,Benoit Bernayet al. Neurobiology of Aging, 2015, 36 (3), pp.1601.e7-1601.e16. ⟨10.1016/j.neurobiolaging.2014.11.014⟩ Article dans une revue hal-02459770v1
Striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo. Laetitia Francelle,Laurie Galvan,Marie-Claude Gaillard,Fanny Petit,Benoît Bernayet al. Neurobiology of Aging, 2015, pp.1601.e7-16. ⟨10.1016/j.neurobiolaging.2014.11.014⟩ Article dans une revue hal-01465910v1
Impaired brain energy metabolism in the BACHD mouse model of Huntington's disease: critical role of astrocyte-neuron interactions Lydie Boussicault,Anne-Sophie Herard,Noel Calingasan,Fanny Petit,Carole Malgornet al. Journal of Cerebral Blood Flow and Metabolism, 2014, 34 (9), pp.1500-1510. ⟨10.1038/jcbfm.2014.110⟩ Article dans une revue hal-01545792v1
SET translocation is associated with increase in caspase cleaved amyloid precursor protein in CA1 of Alzheimer and Down syndrome patients. Patricia Facchinetti,Emilie Dorard,Vincent Contremoulins,Marie-Claude Gaillard,Nicole Déglonet al. Neurobiol Aging, 2014, 35 (5), pp.958-68. ⟨10.1016/j.neurobiolaging.2013.08.039⟩ Article dans une revue istex hal-00946234v1
Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's disease Laetitia Francelle,Laurie Galvan,Emmanuel Brouillet Frontiers in Cellular Neuroscience, 2014, ⟨10.3389/fncel.2014.00295⟩ Article dans une revue hal-02459873v1
IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates. Romina Aron Badin,Brigitte Spinnewyn,Marie-Claude Gaillard,Caroline Jan,Carole Malgornet al. PLoS ONE, 2013, 8 (1), pp.e52680. ⟨10.1371/journal.pone.0052680⟩ Article dans une revue inserm-00857944v1
A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin Maria Damiano,Elsa Diguet,Carole Malgorn,Marilena d'Aurelio,Laurie Galvanet al. Human Molecular Genetics, 2013, 22 (19), pp.3869-3882. ⟨10.1093/hmg/ddt242⟩ Article dans une revue hal-02459752v1
Ectosomes: a new mechanism for non-exosomal secretion of tau protein. Simon Dujardin,Séverine Bégard,Raphaëlle Caillierez,Cédrick Lachaud,Lucie Delattreet al. PLoS ONE, 2013, 9 (6), pp.e100760. ⟨10.1371/journal.pone.0100760⟩ Article dans une revue hal-01181185v1
Capucin does not modify the toxicity of a mutant Huntingtin fragment in vivo Laurie Galvan,Nad'A Lepejová,Marie-Claude Gaillard,Carole Malgorn,Martine Guillermieret al. Neurobiology of Aging, 2012, 33 (8), pp.1845.e5-1845.e6. ⟨10.1016/j.neurobiolaging.2012.01.009⟩ Article dans une revue istex hal-02459764v1
The Nrf2 pathway as a potential therapeutic target for Huntington disease. A commentary on “Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington disease” Carole Escartin,Emmanuel Brouillet Free Radical Biology and Medicine, 2010, 49 (2), pp.144-146. ⟨10.1016/j.freeradbiomed.2010.04.009⟩ Article dans une revue istex cea-02168439v1
Mitochondria in Huntington's disease Maria Damiano,Laurie Galvan,Nicole Déglon,Emmanuel Brouillet Biochimica et Biophysica Acta - Molecular Basis of Disease, 2010, 1802 (1), pp.52-61. ⟨10.1016/j.bbadis.2009.07.012⟩ Article dans une revue hal-02459756v1
Mitochondria in Huntington's disease Maria Damiano,Laurie Galvan,Nicole Déglon,Emmanuel Brouillet Biochimica et Biophysica Acta - Molecular Basis of Disease, 2009, 1802 (1), pp.52. ⟨10.1016/j.bbadis.2009.07.012⟩ Article dans une revue hal-00543005v1
Normal Aging Modulates the Neurotoxicity of Mutant Huntingtin Elsa Diguet,Fanny Petit,Carole Escartin,Karine Cambon,Nicolas Bizatet al. PLoS ONE, 2009, 4 (2), pp.e4637. ⟨10.1371/journal.pone.0004637⟩ Article dans une revue cea-02290598v1
Discovering new bioactive neuropeptides in the striatum secretome using in vivo microdialysis and versatile proteomics. Benoît Bernay,Marie-Claude Gaillard,Vilém Guryca,Anouk Emadali,Lauriane Kuhnet al. Molecular and Cellular Proteomics, 2009, 8 (5), pp.946-58. ⟨10.1074/mcp.M800501-MCP200⟩ Article dans une revue inserm-00410894v1
Dopamine Gene Therapy for Parkinson’s Disease in a Nonhuman Primate Without Associated Dyskinesia Béchir Jarraya,Sabrina Boulet,G. Scott Ralph,Caroline Jan,Gilles Bonventoet al. Science Translational Medicine, 2009, 1 (2), ⟨10.1126/scitranslmed.3000130⟩ Article dans une revue hal-03978589v1
Quantitative gene expression profiling of mouse brain regions reveals differential transcripts conserved in human and affected in disease models. Camille Brochier,Marie-Claude Gaillard,Elsa Diguet,Nicolas Caudy,Carole Dossatet al. Physiological Genomics, 2008, 33 (2), pp.170-9. ⟨10.1152/physiolgenomics.00125.2007⟩ Article dans une revue hal-00275419v1
IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats Carole Escartin,Frédéric Boyer,Alexis-Pierre Bemelmans,Philippe Hantraye,Emmanuel Brouillet Neuroscience Letters, 2007, 425 (3), pp.167-172. ⟨10.1016/j.neulet.2007.08.031⟩ Article dans une revue cea-02290618v1
Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo. Delphine Charvin,Emmanuel Roze,Valérie Perrin,Carole Deyts,Sandrine Betuinget al. Neurobiology of Disease, 2007, 29 (1), pp.22-29. ⟨10.1016/j.nbd.2007.07.028⟩ Article dans une revue hal-00181915v1
Activation of Astrocytes by CNTF Induces Metabolic Plasticity and Increases Resistance to Metabolic Insults Carole Escartin,Karin Pierre,Angélique Colin,Emmanuel Brouillet,Thierry Delzescauxet al. Journal of Neuroscience, 2007, 27 (27), pp.7094-7104. ⟨10.1523/JNEUROSCI.0174-07.2007⟩ Article dans une revue cea-02290623v1
Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation Carine Jacquard,Yael Trioulier,François Cosker,Carole Escartin,Nicolas Bizatet al. FASEB Journal, 2006, 20(7), pp.1021-1023. ⟨10.1096/fj.05-5085fje⟩ Article dans une revue hal-00103460v1
CA150 expression delays striatal cell death in overexpression and knock-in conditions for mutant huntingtin neurotoxicity Margarita Arango,Sébastien Holbert,Dania Zala,Emmanuel Brouillet,James Pearsonet al. Journal of Neuroscience, 2006, 26 (17), pp.4649 - 4659. ⟨10.1523/JNEUROSCI.5409-05.2006⟩ Article dans une revue hal-02666883v1
Insulin growth factor-1 protects against excitotoxicity in the rat striatum Carole Escartin,Frédéric Boyer,Alexis-Pierre Bemelmans,Philippe Hantraye,Emmanuel Brouillet NeuroReport, 2004, 15 (14), pp.2251-2254. ⟨10.1097/00001756-200410050-00022⟩ Article dans une revue cea-02290615v1
Calpain is a major cell death effector in selective striatal degeneration induced $in\ vivo$ by 3-nitropropionate: implications for Huntington's disease. Nicolas Bizat,Jean-Michel Hermel,Frédéric Boyer,Carine Jacquard,Christophe Créminonet al. Journal of Neuroscience, 2003, 23 (12), pp.5020-30 Article dans une revue cea-02290630v1
$In\ Vivo$ Calpain/Caspase Cross-talk during 3-Nitropropionic Acid-induced Striatal Degeneration Nicolas Bizat,Jean-Michel Hermel,Sandrine Humbert,Carine Jacquard,Christophe Créminonet al. Journal of Biological Chemistry, 2003, 278 (44), pp.43245-43253. ⟨10.1074/jbc.M305057200⟩ Article dans une revue cea-02290633v1
The Mitochondrial Toxin 3-Nitropropionic Acid Induces Striatal Neurodegeneration via a c-Jun N-Terminal Kinase/c-Jun Module Marta Garcia,Peter Vanhoutte,Christiane Pagès,Marie-Jo Besson,Emmanuel Brouilletet al. Journal of Neuroscience, 2002, 22 (6), pp.2174-2184. ⟨10.1523/JNEUROSCI.22-06-02174.2002⟩ Article dans une revue hal-02372666v1
Corticostriatopallidal Neuroprotection by Adenovirus-Mediated Ciliary Neurotrophic Factor Gene Transfer in a Rat Model of Progressive Striatal Degeneration Vincent Mittoux,Stephane Ouary,Christelle Monville,Fabrice Lisovoski,Thomas Poyotet al. Journal of Neuroscience, 2002, 22 (11), pp.4478-86 Article dans une revue cea-02290628v1
Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid. Nicole El Massioui,Stéphane Ouary,Fabrice Chéruel,Philippe Hantraye,Emmanuel Brouillet Experimental Neurology, 2001, 172 (1), pp.172-81. ⟨10.1006/exnr.2001.7766⟩ Article dans une revue istex hal-01467542v1

Pré-publication, Document de travail (1)

Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease Océane Guillemaud,Kelly Ceyzériat,Thomas Saint-Georges,Karine Cambon,Fanny Petitet al. 2019 Pré-publication, Document de travail cea-02392438v1

Communication dans un congrès (1)

The newly identified striatal marker Doublecortin-like kinase 3 (Dclk3) may be a molecular determinant of striatal vulnerability in Huntington’s disease L. Francelle,Laurie Galvan,M.-C Gaillard,G. Liot,M de Chaldée d'Abbaset al. SFN 2013, Nov 2013, SAN DIEGO, United States Communication dans un congrès hal-02534692v1