Eric Legrand

Documents

Publications

	Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine and polymorphism in Plasmodium falciparum kelch13-propeller gene in Equatorial Guinea Matilde Riloha Rivas , Marian Warsame , Ramona Mbá Andeme , Salomón Nsue Esidang , Policarpo Ricardo Ncogo Malaria Journal, 2021, 20 (1), pp.275. ⟨10.1186/s12936-021-03807-x⟩ Journal articles pasteur-03273687v1
	Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness Barbara H. Stokes , Satish K. Dhingra , Kelly Rubiano , Sachel Mok , Judith Straimer eLife, 2021, 10, pp.e66277. ⟨10.7554/eLife.66277⟩ Journal articles pasteur-03291682v1
	Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda Aline Uwimana , Eric Legrand , Barbara Stokes , Jean-Louis Mangala Ndikumana , Marian Warsame Nature Medicine, 2020, ⟨10.1038/s41591-020-1005-2⟩ Journal articles pasteur-02911712v1
	Human Plasmodium vivax diversity, population structure and evolutionary origin Virginie Rougeron , Eric Elguero , Céline Arnathau , Beatriz Acuña Hidalgo , Durand Patrick PLoS Neglected Tropical Diseases, 2020, 14 (3), pp.e0008072. ⟨10.1371/journal.pntd.0008072⟩ Journal articles pasteur-02567249v1
	Enteroendocrine K Cells Exert Complementary Effects to Control Bone Quality and Mass in Mice Benoît Gobron , Béatrice Bouvard , Sagar Vyavahare , Liv Vv V V Blom , Kristian K Pedersen Journal of Bone and Mineral Research, 2020, 35 (7), pp.1363-1374. ⟨10.1002/jbmr.4004⟩ Journal articles hal-02946043v1
	WHO malaria nucleic acid amplification test external quality assessment scheme: results of distribution programmes one to three Jane Cunningham , Rebecca Thomson , Sean Murphy , Maria de La Paz Ade , Xavier Ding Malaria Journal, 2020, 19, pp.129. ⟨10.1186/s12936-020-03200-0⟩ Journal articles hal-02558622v1
	Emergence of Plasmodium vivax Resistance to Chloroquine in French Guiana Lise Musset , Christophe Heugas , Richard Naldjinan , Denis Blanchet , Pascal Houzé Antimicrobial Agents and Chemotherapy, 2019, 63 (11), ⟨10.1128/AAC.02116-18⟩ Journal articles pasteur-02567258v1
	African isolates show a high proportion of multiple copies of the Plasmodium falciparum plasmepsin-2 gene, a piperaquine resistance marker Didier Leroy , Fiona Macintyre , Yeka Adoke , Serge Ouoba , Aissata Barry Malaria Journal, 2019, 18, pp.126. ⟨10.1186/s12936-019-2756-4⟩ Journal articles hal-02558674v1
	Asymptomatic Plasmodium vivax infections among Duffy-negative population in Kedougou, Senegal Makhtar Niang , Rokhaya Sane , Abdourahmane Sow , Bacary Sadio , Sophy Chy Tropical Medicine and Health, 2018, 46, pp.45. ⟨10.1186/s41182-018-0128-3⟩ Journal articles hal-02558691v1
	Evolutionary structure of Plasmodium falciparum major variant surface antigen genes in South America: Implications for epidemic transmission and surveillance Virginie Rougeron , Kathryn E Tiedje , Donald S Chen , Thomas S Rask , Dionicia Gamboa BMC Evolutionary Biology, 2017, 7 (22), pp.9376-9390. ⟨10.1002/ece3.3425⟩ Journal articles pasteur-01621487v1
	Antiplasmodial activities of dyes against Plasmodium falciparum asexual and sexual stages: Contrasted uptakes of triarylmethanes Brilliant green, Green S (E142), and Patent Blue V (E131) by erythrocytes Louis-Jérôme Leba , Jean Popovici , Yannick Estevez , Stéphane Pelleau , Eric Legrand International journal for parasitology. Drugs and drug resistance, 2017, 7 (3), pp.314 - 320. ⟨10.1016/j.ijpddr.2017.07.002⟩ Journal articles pasteur-01614675v1
	A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study Benoit Witkowski , Valentine Duru , Nimol Khim , Leila S Ross , Benjamin Saintpierre The Lancet Infectious Diseases, 2016, 17 (2), pp.174-183. ⟨10.1016/S1473-3099(16)30415-7⟩ Journal articles pasteur-01400955v1
	EVALUATION OF CIRCUMSPOROZOITE PROTEIN OF Plasmodium vivax TO ESTIMATE ITS PREVALENCE IN OIAPOQUE , AMAPÁ STATE, BRAZIL, BORDERING FRENCH GUIANA Margarete Do Socorro Mendonça Gomes , José Luiz Fernandes Vieira , Gustavo Capatti Cassiano , Lise Musset , Eric Legrand Revista do Instituto de Medicina Tropical de São Paulo, 2016, 58, pp.72. ⟨10.1590/S1678-9946201658072⟩ Journal articles hal-01372566v1
	French law: what about a reasoned reimbursement of serum vitamin D assays? Jc Souberbielle , France Benhamou , Bernard Cortet , France Rousière , France Roux Gériatrie et psychologie & neuropsychiatrie du vieillissement, 2016, 14 (4), pp.377-382. ⟨10.1684/pnv.2016.0631⟩ Journal articles hal-01465951v1
	Plasmodium vivax multidrug resistance-1 gene polymorphism in French Guiana Emilie Faway , Lise Musset , Stéphane Pelleau , Béatrice Volney , Jessica Casteras Malaria Journal, 2016, 15 (1), pp.540. ⟨10.1186/s12936-016-1595-9⟩ Journal articles pasteur-01400964v1
	Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes. Johann Beghain , Anne-Claire Langlois , Eric Legrand , Laura Grange , Nimol Khim Malaria Journal, 2016, 15 (1), pp.206. ⟨10.1186/s12936-016-1258-x⟩ Journal articles pasteur-01303621v1
	Malaria Hyperendemicity and Risk for Artemisinin Resistance among Illegal Gold Miners, French Guiana. Vincent Pommier de Santi , Félix Djossou , Nicolas Barthes , Herve Bogreau , Georges Hyvert Emerging Infectious Diseases, 2016, 22 (5), pp.903-6. ⟨10.3201/eid2205.151957⟩ Journal articles pasteur-01305106v1
	A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms. Didier Ménard , Nimol Khim , Johann Beghain , Ayola A Adegnika , Mohammad Shafiul-Alam New England Journal of Medicine, 2016, 374 (25), pp.2453-64. ⟨10.1056/NEJMoa1513137⟩ Journal articles pasteur-01336483v1
	Heterogeneity among Mycobacterium ulcerans from French Guiana Revealed by Multilocus Variable Number Tandem Repeat Analysis (MLVA). Yann Reynaud , Julie Millet , David Couvin , Nalin Rastogi , Christopher Brown PLoS ONE, 2015, 10 (2), pp.e0118597. ⟨10.1371/journal.pone.0118597⟩ Journal articles pasteur-01133543v1
	Frequency and distribution of mixed Plasmodium falciparum-vivax infections in French Guiana between 2000 and 2008. Marine Ginouvès , Vincent Veron , Lise Musset , Eric Legrand , Aurelia Stefani Malaria Journal, 2015, 14 (1), pp.446. ⟨10.1186/s12936-015-0971-1⟩ Journal articles pasteur-01229359v1
	Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay. Louis-Jérôme Leba , Lise Musset , Stéphane Pelleau , Yannick Estevez , Caroline Birer Malaria Journal, 2015, 14, pp.234. ⟨10.1186/s12936-015-0752-x⟩ Journal articles hal-01182753v1
	Absence of correlation between ex vivo susceptibility to doxycycline and pfteQ–pfmdt gene polymorphism in French Guiana Marie Mura , Sébastien Briolant , Damien Donato , Béatrice Volney , Stéphane Pelleau Malaria Journal, 2015, 14 (1), pp.286. ⟨10.1186/s12936-015-0788-y⟩ Journal articles hal-01182758v1
	Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt. Stéphane Pelleau , Eli L Moss , Satish K Dhingra , Béatrice Volney , Jessica Casteras Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (37), pp.11672-11677. ⟨10.1073/pnas.1507142112⟩ Journal articles hal-01229321v1
	Efficacy in the treatment of malaria by Plasmodium vivax in Oiapoque, Brazil, on the border with French Guiana: the importance of control over external factors. Margarete Do Socorro M Gomes , José Luiz F Vieira , Ricardo L D Machado , Mathieu Nacher , Aurelia Stefani Malaria Journal, 2015, 14 (1), pp.402. ⟨10.1186/s12936-015-0925-7⟩ Journal articles hal-01229355v1
	Development of a Single Nucleotide Polymorphism Barcode to Genotype Plasmodium vivax Infections. Mary Lynn Baniecki , Aubrey L Faust , Stephen F Schaffner , Daniel J Park , Kevin Galinsky PLoS Neglected Tropical Diseases, 2015, 9 (3), pp.e0003539. ⟨10.1371/journal.pntd.0003539⟩ Journal articles pasteur-01133539v1
	Multiple independent introductions of Plasmodium falciparum in South America. Erhan Yalcindag , Eric Elguero , Céline Arnathau , Durand Patrick , Jean Akiana Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (2), pp.511-6. ⟨10.1073/pnas.1119058109⟩ Journal articles pasteur-00705564v1
	Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after drug policy change in French Guiana. Eric Legrand , Joséphine Yrinesi , Marie-Thérèse Ekala , Julie Péneau , Béatrice Volney Antimicrobial Agents and Chemotherapy, 2012, 56 (3), pp.1382-9. ⟨10.1128/AAC.05280-11⟩ Journal articles pasteur-00705562v1
	Investigation of a sudden malaria outbreak in the isolated Amazonian village of Saul, French Guiana, January-April 2009. Franck Berger , Claude Flamand , Lise Musset , Félix Djossou , Jacques Rosine American Journal of Tropical Medicine and Hygiene, 2012, 86 (4), pp.591-7. ⟨10.4269/ajtmh.2012.11-0582⟩ Journal articles pasteur-00705561v1
	Geographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity. Ronan Jambou , Axel Martinelli , João Pinto , Simonetta Gribaldo , Eric Legrand PLoS ONE, 2010, 5 (2), pp.e9424. ⟨10.1371/journal.pone.0009424⟩ Journal articles pasteur-00590979v1
	Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum. Stephanie G Valderramos , Juan-Carlos Valderramos , Lise Musset , Lisa A Purcell , Odile Mercereau-Puijalon PLoS Pathogens, 2010, 6 (5), pp.e1000887. ⟨10.1371/journal.ppat.1000887⟩ Journal articles pasteur-00577266v1
	High prevalence and fixation of Plasmodium vivax dhfr/dhps mutations related to sulfadoxine/pyrimethamine resistance in French Guiana. Céline Barnadas , Lise Musset , Eric Legrand , Magali Tichit , Sébastien Briolant American Journal of Tropical Medicine and Hygiene, 2009, 81 (1), pp.19-22. ⟨10.4269/ajtmh.2009.81.19⟩ Journal articles pasteur-00577267v1
	Genetic diversity of msp3alpha and msp1_b5 markers of Plasmodium vivax in French Guiana. Vincent Veron , Eric Legrand , Joséphine Yrinesi , Béatrice Volney , Stéphane Simon Malaria Journal, 2009, 8, pp.40. ⟨10.1186/1475-2875-8-40⟩ Journal articles pasteur-00590981v1
	In vitro monitoring of Plasmodium falciparum drug resistance in French Guiana: a synopsis of continuous assessment from 1994 to 2005. Eric Legrand , Béatrice Volney , Jean-Baptiste Meynard , Odile Mercereau-Puijalon , Philippe Esterre Antimicrobial Agents and Chemotherapy, 2008, 52 (1), pp.288-98. ⟨10.1128/AAC.00263-07⟩ Journal articles pasteur-00590986v1
	Dihydroethanoanthracene derivatives reverse in vitro quinoline resistance in Plasmodium falciparum malaria. Maud Henry , Sandrine Alibert , Meili Baragatti , Joel Mosnier , Eric Baret Medicinal Chemistry, 2008, 4 (5), pp.426-437. ⟨10.2174/157340608785700234⟩ Journal articles pasteur-00590982v1
	Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites. Marie-Thérèse Ekala , Nimol Khim , Eric Legrand , Milijaona Randrianarivelojosia , Ronan Jambou Malaria Journal, 2007, 6, pp.164. ⟨10.1186/1475-2875-6-164⟩ Journal articles pasteur-00590983v1
	Resistance to dihydroartemisinin. Eric Legrand , Beatrice Volney , Jean-Baptiste Meynard , Philippe Esterre , Odile Mercereau-Puijalon Emerging Infectious Diseases, 2007, 13 (5), 808-9; author reply 809. ⟨10.3201/eid1305.061442⟩ Journal articles pasteur-00590984v1
	Evaluation of the intra- and inter-specific genetic variability of Plasmodium lactate dehydrogenase. Arthur M. Talman , Linda Duval , Eric Legrand , Véronique Hubert , Seiha Yen Malaria Journal, 2007, 6, pp.140. ⟨10.1186/1475-2875-6-140⟩ Journal articles pasteur-00590985v1
	First case of emergence of atovaquone resistance in Plasmodium falciparum during second-line atovaquone-proguanil treatment in South America. Eric Legrand , Magalie Pierre Demar , Béatrice Volney , Marie-Thérèse Ekala , Marc Quinternet Antimicrobial Agents and Chemotherapy, 2007, 51 (6), pp.2280-1. ⟨10.1128/AAC.01532-06⟩ Journal articles pasteur-00590987v1
	Invasion of Africa by a single pfcrt allele of South East Asian type. Frédéric Ariey , Thierry Fandeur , Remy Durand , Milijaona Randrianarivelojosia , Ronan Jambou Malaria Journal, 2006, 5, pp.34. ⟨10.1186/1475-2875-5-34⟩ Journal articles pasteur-00590988v1
	Countrywide survey shows very high prevalence of Plasmodium falciparum multilocus resistance genotypes in Cambodia. Nimol Khim , Christiane Bouchier , Marie-Thérèse Ekala , Sandra Incardona , Pharath Lim Antimicrobial Agents and Chemotherapy, 2005, 49 (8), pp.3147-52. ⟨10.1128/AAC.49.8.3147-3152.2005⟩ Journal articles pasteur-00590990v1
	Molecular analysis of two local falciparum malaria outbreaks on the French Guiana coast confirms the msp1 B-K1/varD genotype association with severe malaria. Eric Legrand , Beatrice Volney , Anne Lavergne , Caroline Tournegros , Loïc Florent Malaria Journal, 2005, 4, pp.26. ⟨10.1186/1475-2875-4-26⟩ Journal articles pasteur-00590991v1
	Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6. Ronan Jambou , Eric Legrand , Makhtar Niang , Nimol Khim , Pharath Lim The Lancet, 2005, 366 (9501), pp.1960-3. ⟨10.1016/S0140-6736(05)67787-2⟩ Journal articles pasteur-00590989v1
	Plasmodium falciparum malaria in splenectomized patients: two case reports in French Guiana and a literature review. Magalie Pierre Demar , Eric Legrand , Didier Hommel , Philippe Esterre , Bernard Carme American Journal of Tropical Medicine and Hygiene, 2004, 71 (3), pp.290-293. ⟨10.4269/ajtmh.2004.71.290⟩ Journal articles pasteur-00590993v1

Eric Legrand

Publications

Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine and polymorphism in Plasmodium falciparum kelch13-propeller gene in Equatorial Guinea

Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda

Human Plasmodium vivax diversity, population structure and evolutionary origin

Enteroendocrine K Cells Exert Complementary Effects to Control Bone Quality and Mass in Mice

WHO malaria nucleic acid amplification test external quality assessment scheme: results of distribution programmes one to three

Emergence of Plasmodium vivax Resistance to Chloroquine in French Guiana

African isolates show a high proportion of multiple copies of the Plasmodium falciparum plasmepsin-2 gene, a piperaquine resistance marker

Asymptomatic Plasmodium vivax infections among Duffy-negative population in Kedougou, Senegal

Evolutionary structure of Plasmodium falciparum major variant surface antigen genes in South America: Implications for epidemic transmission and surveillance

Antiplasmodial activities of dyes against Plasmodium falciparum asexual and sexual stages: Contrasted uptakes of triarylmethanes Brilliant green, Green S (E142), and Patent Blue V (E131) by erythrocytes

A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study

EVALUATION OF CIRCUMSPOROZOITE PROTEIN OF Plasmodium vivax TO ESTIMATE ITS PREVALENCE IN OIAPOQUE , AMAPÁ STATE, BRAZIL, BORDERING FRENCH GUIANA

French law: what about a reasoned reimbursement of serum vitamin D assays?

Plasmodium vivax multidrug resistance-1 gene polymorphism in French Guiana

Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes.

Malaria Hyperendemicity and Risk for Artemisinin Resistance among Illegal Gold Miners, French Guiana.

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

Heterogeneity among Mycobacterium ulcerans from French Guiana Revealed by Multilocus Variable Number Tandem Repeat Analysis (MLVA).

Frequency and distribution of mixed Plasmodium falciparum-vivax infections in French Guiana between 2000 and 2008.

Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay.

Absence of correlation between ex vivo susceptibility to doxycycline and pfteQ–pfmdt gene polymorphism in French Guiana

Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt.

Efficacy in the treatment of malaria by Plasmodium vivax in Oiapoque, Brazil, on the border with French Guiana: the importance of control over external factors.

Development of a Single Nucleotide Polymorphism Barcode to Genotype Plasmodium vivax Infections.

Multiple independent introductions of Plasmodium falciparum in South America.

Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after drug policy change in French Guiana.

Investigation of a sudden malaria outbreak in the isolated Amazonian village of Saul, French Guiana, January-April 2009.

Geographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity.

Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum.

High prevalence and fixation of Plasmodium vivax dhfr/dhps mutations related to sulfadoxine/pyrimethamine resistance in French Guiana.

Genetic diversity of msp3alpha and msp1_b5 markers of Plasmodium vivax in French Guiana.

In vitro monitoring of Plasmodium falciparum drug resistance in French Guiana: a synopsis of continuous assessment from 1994 to 2005.

Dihydroethanoanthracene derivatives reverse in vitro quinoline resistance in Plasmodium falciparum malaria.

Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites.

Resistance to dihydroartemisinin.

Evaluation of the intra- and inter-specific genetic variability of Plasmodium lactate dehydrogenase.

First case of emergence of atovaquone resistance in Plasmodium falciparum during second-line atovaquone-proguanil treatment in South America.

Invasion of Africa by a single pfcrt allele of South East Asian type.

Countrywide survey shows very high prevalence of Plasmodium falciparum multilocus resistance genotypes in Cambodia.

Molecular analysis of two local falciparum malaria outbreaks on the French Guiana coast confirms the msp1 B-K1/varD genotype association with severe malaria.

Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

Plasmodium falciparum malaria in splenectomized patients: two case reports in French Guiana and a literature review.