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Eric Legrand



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Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

Barbara H. Stokes , Satish K. Dhingra , Kelly Rubiano , Sachel Mok , Judith Straimer
eLife, 2021, 10, pp.e66277. ⟨10.7554/eLife.66277⟩
Journal articles pasteur-03291682v1
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Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine and polymorphism in Plasmodium falciparum kelch13-propeller gene in Equatorial Guinea

Matilde Riloha Rivas , Marian Warsame , Ramona Mbá Andeme , Salomón Nsue Esidang , Policarpo Ricardo Ncogo
Malaria Journal, 2021, 20 (1), pp.275. ⟨10.1186/s12936-021-03807-x⟩
Journal articles pasteur-03273687v1
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WHO malaria nucleic acid amplification test external quality assessment scheme: results of distribution programmes one to three

Jane Cunningham , Rebecca Thomson , Sean Murphy , Maria de La Paz Ade , Xavier Ding
Malaria Journal, 2020, 19, pp.129. ⟨10.1186/s12936-020-03200-0⟩
Journal articles hal-02558622v1
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Enteroendocrine K Cells Exert Complementary Effects to Control Bone Quality and Mass in Mice

Benoît Gobron , Béatrice Bouvard , Sagar Vyavahare , Liv Vv V V Blom , Kristian K Pedersen
Journal of Bone and Mineral Research, 2020, 35 (7), pp.1363-1374. ⟨10.1002/jbmr.4004⟩
Journal articles hal-02946043v1
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Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda

Aline Uwimana , Eric Legrand , Barbara Stokes , Jean-Louis Mangala Ndikumana , Marian Warsame
Nature Medicine, 2020, ⟨10.1038/s41591-020-1005-2⟩
Journal articles pasteur-02911712v1
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Human Plasmodium vivax diversity, population structure and evolutionary origin

Virginie Rougeron , Eric Elguero , Céline Arnathau , Beatriz Acuña Hidalgo , Durand Patrick
PLoS Neglected Tropical Diseases, 2020, 14 (3), pp.e0008072. ⟨10.1371/journal.pntd.0008072⟩
Journal articles pasteur-02567249v1
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African isolates show a high proportion of multiple copies of the Plasmodium falciparum plasmepsin-2 gene, a piperaquine resistance marker

Didier Leroy , Fiona Macintyre , Yeka Adoke , Serge Ouoba , Aissata Barry
Malaria Journal, 2019, 18, pp.126. ⟨10.1186/s12936-019-2756-4⟩
Journal articles hal-02558674v1
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Emergence of Plasmodium vivax Resistance to Chloroquine in French Guiana

Lise Musset , Christophe Heugas , Richard Naldjinan , Denis Blanchet , Pascal Houzé
Antimicrobial Agents and Chemotherapy, 2019, 63 (11), ⟨10.1128/AAC.02116-18⟩
Journal articles pasteur-02567258v1
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Asymptomatic Plasmodium vivax infections among Duffy-negative population in Kedougou, Senegal

Makhtar Niang , Rokhaya Sane , Abdourahmane Sow , Bacary Sadio , Sophy Chy
Tropical Medicine and Health, 2018, 46, pp.45. ⟨10.1186/s41182-018-0128-3⟩
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Antiplasmodial activities of dyes against Plasmodium falciparum asexual and sexual stages: Contrasted uptakes of triarylmethanes Brilliant green, Green S (E142), and Patent Blue V (E131) by erythrocytes

Louis-Jérôme Leba , Jean Popovici , Yannick Estevez , Stéphane Pelleau , Eric Legrand
International journal for parasitology. Drugs and drug resistance, 2017, 7 (3), pp.314 - 320. ⟨10.1016/j.ijpddr.2017.07.002⟩
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Evolutionary structure of Plasmodium falciparum major variant surface antigen genes in South America: Implications for epidemic transmission and surveillance

Virginie Rougeron , Kathryn E Tiedje , Donald S Chen , Thomas S Rask , Dionicia Gamboa
BMC Evolutionary Biology, 2017, 7 (22), pp.9376-9390. ⟨10.1002/ece3.3425⟩
Journal articles pasteur-01621487v1
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Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes.

Johann Beghain , Anne-Claire Langlois , Eric Legrand , Laura Grange , Nimol Khim
Malaria Journal, 2016, 15 (1), pp.206. ⟨10.1186/s12936-016-1258-x⟩
Journal articles pasteur-01303621v1
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A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study

Benoit Witkowski , Valentine Duru , Nimol Khim , Leila S Ross , Benjamin Saintpierre
The Lancet Infectious Diseases, 2016, 17 (2), pp.174-183. ⟨10.1016/S1473-3099(16)30415-7⟩
Journal articles pasteur-01400955v1
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Margarete Do Socorro Mendonça Gomes , José Luiz Fernandes Vieira , Gustavo Capatti Cassiano , Lise Musset , Eric Legrand
Revista do Instituto de Medicina Tropical de São Paulo, 2016, 58, pp.72. ⟨10.1590/S1678-9946201658072⟩
Journal articles hal-01372566v1
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Malaria Hyperendemicity and Risk for Artemisinin Resistance among Illegal Gold Miners, French Guiana.

Vincent Pommier de Santi , Félix Djossou , Nicolas Barthes , Herve Bogreau , Georges Hyvert
Emerging Infectious Diseases, 2016, 22 (5), pp.903-6. ⟨10.3201/eid2205.151957⟩
Journal articles pasteur-01305106v1
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Plasmodium vivax multidrug resistance-1 gene polymorphism in French Guiana

Emilie Faway , Lise Musset , Stéphane Pelleau , Béatrice Volney , Jessica Casteras
Malaria Journal, 2016, 15 (1), pp.540. ⟨10.1186/s12936-016-1595-9⟩
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French law: what about a reasoned reimbursement of serum vitamin D assays?

Jc Souberbielle , France Benhamou , Bernard Cortet , France Rousière , France Roux
Gériatrie et psychologie & neuropsychiatrie du vieillissement, 2016, 14 (4), pp.377-382. ⟨10.1684/pnv.2016.0631⟩
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A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

Didier Ménard , Nimol Khim , Johann Beghain , Ayola A Adegnika , Mohammad Shafiul-Alam
New England Journal of Medicine, 2016, 374 (25), pp.2453-64. ⟨10.1056/NEJMoa1513137⟩
Journal articles pasteur-01336483v1
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Development of a Single Nucleotide Polymorphism Barcode to Genotype Plasmodium vivax Infections.

Mary Lynn Baniecki , Aubrey L Faust , Stephen F Schaffner , Daniel J Park , Kevin Galinsky
PLoS Neglected Tropical Diseases, 2015, 9 (3), pp.e0003539. ⟨10.1371/journal.pntd.0003539⟩
Journal articles pasteur-01133539v1
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Efficacy in the treatment of malaria by Plasmodium vivax in Oiapoque, Brazil, on the border with French Guiana: the importance of control over external factors.

Margarete Do Socorro M Gomes , José Luiz F Vieira , Ricardo L D Machado , Mathieu Nacher , Aurelia Stefani
Malaria Journal, 2015, 14 (1), pp.402. ⟨10.1186/s12936-015-0925-7⟩
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Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay.

Louis-Jérôme Leba , Lise Musset , Stéphane Pelleau , Yannick Estevez , Caroline Birer
Malaria Journal, 2015, 14, pp.234. ⟨10.1186/s12936-015-0752-x⟩
Journal articles hal-01182753v1
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Heterogeneity among Mycobacterium ulcerans from French Guiana Revealed by Multilocus Variable Number Tandem Repeat Analysis (MLVA).

Yann Reynaud , Julie Millet , David Couvin , Nalin Rastogi , Christopher Brown
PLoS ONE, 2015, 10 (2), pp.e0118597. ⟨10.1371/journal.pone.0118597⟩
Journal articles pasteur-01133543v1
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Frequency and distribution of mixed Plasmodium falciparum-vivax infections in French Guiana between 2000 and 2008.

Marine Ginouvès , Vincent Veron , Lise Musset , Eric Legrand , Aurelia Stefani
Malaria Journal, 2015, 14 (1), pp.446. ⟨10.1186/s12936-015-0971-1⟩
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Absence of correlation between ex vivo susceptibility to doxycycline and pfteQ–pfmdt gene polymorphism in French Guiana

Marie Mura , Sébastien Briolant , Damien Donato , Béatrice Volney , Stéphane Pelleau
Malaria Journal, 2015, 14 (1), pp.286. ⟨10.1186/s12936-015-0788-y⟩
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Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt.

Stéphane Pelleau , Eli L Moss , Satish K Dhingra , Béatrice Volney , Jessica Casteras
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (37), pp.11672-11677. ⟨10.1073/pnas.1507142112⟩
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Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after drug policy change in French Guiana.

Eric Legrand , Joséphine Yrinesi , Marie-Thérèse Ekala , Julie Péneau , Béatrice Volney
Antimicrobial Agents and Chemotherapy, 2012, 56 (3), pp.1382-9. ⟨10.1128/AAC.05280-11⟩
Journal articles pasteur-00705562v1
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Investigation of a sudden malaria outbreak in the isolated Amazonian village of Saul, French Guiana, January-April 2009.

Franck Berger , Claude Flamand , Lise Musset , Félix Djossou , Jacques Rosine
American Journal of Tropical Medicine and Hygiene, 2012, 86 (4), pp.591-7. ⟨10.4269/ajtmh.2012.11-0582⟩
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Multiple independent introductions of Plasmodium falciparum in South America.

Erhan Yalcindag , Eric Elguero , Céline Arnathau , Durand Patrick , Jean Akiana
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (2), pp.511-6. ⟨10.1073/pnas.1119058109⟩
Journal articles pasteur-00705564v1
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Geographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity.

Ronan Jambou , Axel Martinelli , João Pinto , Simonetta Gribaldo , Eric Legrand
PLoS ONE, 2010, 5 (2), pp.e9424. ⟨10.1371/journal.pone.0009424⟩
Journal articles pasteur-00590979v1
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Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum.

Stephanie G Valderramos , Juan-Carlos Valderramos , Lise Musset , Lisa A Purcell , Odile Mercereau-Puijalon
PLoS Pathogens, 2010, 6 (5), pp.e1000887. ⟨10.1371/journal.ppat.1000887⟩
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High prevalence and fixation of Plasmodium vivax dhfr/dhps mutations related to sulfadoxine/pyrimethamine resistance in French Guiana.

Céline Barnadas , Lise Musset , Eric Legrand , Magali Tichit , Sébastien Briolant
American Journal of Tropical Medicine and Hygiene, 2009, 81 (1), pp.19-22. ⟨10.4269/ajtmh.2009.81.19⟩
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Genetic diversity of msp3alpha and msp1_b5 markers of Plasmodium vivax in French Guiana.

Vincent Veron , Eric Legrand , Joséphine Yrinesi , Béatrice Volney , Stéphane Simon
Malaria Journal, 2009, 8, pp.40. ⟨10.1186/1475-2875-8-40⟩
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In vitro monitoring of Plasmodium falciparum drug resistance in French Guiana: a synopsis of continuous assessment from 1994 to 2005.

Eric Legrand , Béatrice Volney , Jean-Baptiste Meynard , Odile Mercereau-Puijalon , Philippe Esterre
Antimicrobial Agents and Chemotherapy, 2008, 52 (1), pp.288-98. ⟨10.1128/AAC.00263-07⟩
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Dihydroethanoanthracene derivatives reverse in vitro quinoline resistance in Plasmodium falciparum malaria.

Maud Henry , Sandrine Alibert , Meili Baragatti , Joel Mosnier , Eric Baret
Medicinal Chemistry, 2008, 4 (5), pp.426-437. ⟨10.2174/157340608785700234⟩
Journal articles pasteur-00590982v1

First case of emergence of atovaquone resistance in Plasmodium falciparum during second-line atovaquone-proguanil treatment in South America.

Eric Legrand , Magalie Pierre Demar , Béatrice Volney , Marie-Thérèse Ekala , Marc Quinternet
Antimicrobial Agents and Chemotherapy, 2007, 51 (6), pp.2280-1. ⟨10.1128/AAC.01532-06⟩
Journal articles pasteur-00590987v1
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Resistance to dihydroartemisinin.

Eric Legrand , Beatrice Volney , Jean-Baptiste Meynard , Philippe Esterre , Odile Mercereau-Puijalon
Emerging Infectious Diseases, 2007, 13 (5), 808-9; author reply 809. ⟨10.3201/eid1305.061442⟩
Journal articles pasteur-00590984v1
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Evaluation of the intra- and inter-specific genetic variability of Plasmodium lactate dehydrogenase.

Arthur M. Talman , Linda Duval , Eric Legrand , Véronique Hubert , Seiha Yen
Malaria Journal, 2007, 6, pp.140. ⟨10.1186/1475-2875-6-140⟩
Journal articles pasteur-00590985v1
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Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites.

Marie-Thérèse Ekala , Nimol Khim , Eric Legrand , Milijaona Randrianarivelojosia , Ronan Jambou
Malaria Journal, 2007, 6, pp.164. ⟨10.1186/1475-2875-6-164⟩
Journal articles pasteur-00590983v1
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Invasion of Africa by a single pfcrt allele of South East Asian type.

Frédéric Ariey , Thierry Fandeur , Remy Durand , Milijaona Randrianarivelojosia , Ronan Jambou
Malaria Journal, 2006, 5, pp.34. ⟨10.1186/1475-2875-5-34⟩
Journal articles pasteur-00590988v1

Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

Ronan Jambou , Eric Legrand , Makhtar Niang , Nimol Khim , Pharath Lim
The Lancet, 2005, 366 (9501), pp.1960-3. ⟨10.1016/S0140-6736(05)67787-2⟩
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Countrywide survey shows very high prevalence of Plasmodium falciparum multilocus resistance genotypes in Cambodia.

Nimol Khim , Christiane Bouchier , Marie-Thérèse Ekala , Sandra Incardona , Pharath Lim
Antimicrobial Agents and Chemotherapy, 2005, 49 (8), pp.3147-52. ⟨10.1128/AAC.49.8.3147-3152.2005⟩
Journal articles pasteur-00590990v1
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Molecular analysis of two local falciparum malaria outbreaks on the French Guiana coast confirms the msp1 B-K1/varD genotype association with severe malaria.

Eric Legrand , Beatrice Volney , Anne Lavergne , Caroline Tournegros , Loïc Florent
Malaria Journal, 2005, 4, pp.26. ⟨10.1186/1475-2875-4-26⟩
Journal articles pasteur-00590991v1

Plasmodium falciparum malaria in splenectomized patients: two case reports in French Guiana and a literature review.

Magalie Pierre Demar , Eric Legrand , Didier Hommel , Philippe Esterre , Bernard Carme
American Journal of Tropical Medicine and Hygiene, 2004, 71 (3), pp.290-293. ⟨10.4269/ajtmh.2004.71.290⟩
Journal articles pasteur-00590993v1