Fabien GOSSELET

117

Documents

Publications

	CD31 orchestrates metabolic regulation in autophagy pathways of rheumatoid arthritis Kenneth Cp Cheung , Jiao Ma , Lu Wang , Xingxuan Chen , Silvia Fanti Pharmacological Research, 2024, 207, ⟨10.1016/j.phrs.2024.107346⟩ Journal articles hal-04670138v1
	Enhancing Oral Delivery of Biologics: A Non-Competitive and Cross-Reactive Anti-Leptin Receptor Nanofitin Demonstrates a Gut-Crossing Capacity in an Ex Vivo Porcine Intestinal Model Solene Masloh , Anne Chevrel , Maxime Culot , Anaëlle Perrocheau , Yogeshvar N Kalia Pharmaceutics, 2024, 16 (1), pp.116. ⟨10.3390/pharmaceutics16010116⟩ Journal articles hal-04413366v1
	25-Hydroxycholesterol attenuates tumor necrosis factor alpha-induced blood-brain barrier breakdown in vitro Rodrigo Azevedo Loiola , Cindy Nguyen , Shiraz Dib , Julien Saint-Pol , Lucie Dehouck Biochimica et Biophysica Acta - Molecular Basis of Disease, 2024, 1870, ⟨10.1016/j.bbadis.2024.167479⟩ Journal articles hal-04683068v1
	Secretome of brain microvascular endothelial cells promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage Rodrigo Azevedo Loiola , Johan Hachani , Sophie Duban-Deweer , Emmanuel Sevin , Paulina Bugno Molecular Medicine, 2024, ⟨10.1186/s10020-024-00897-6⟩ Journal articles hal-04678255v1
	Enterovirus A71 crosses a human blood–brain barrier model through infected immune cells Léa Gaume , Hélène Chabrolles , Maxime Bisseux , Igor Lopez-Coqueiro , Lucie Dehouck Microbiology Spectrum, 2024, ⟨10.1128/spectrum.00690-24⟩ Journal articles hal-04578863v1
	Vesicular Trafficking, a Mechanism Controlled by Cascade Activation of Rab Proteins: Focus on Rab27 Camille Menaceur , Océane Dusailly , Fabien Gosselet , Laurence Fenart , Julien Saint-Pol Biology, 2023, 12, ⟨10.3390/biology12121530⟩ Journal articles hal-04363886v1
	TNFα Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1 Shiraz Dib , Rodrigo Azevedo Loiola , Emmanuel Sevin , Julien Saint-Pol , Fumitaka Shimizu International Journal of Molecular Sciences, 2023, 24 (6), ⟨10.3390/ijms24065992⟩ Journal articles hal-04053087v1
	BrainBike peptidomimetic enables efficient transport of proteins across brain endothelium Maria C Lucana , Roberta Lucchi , Fabien Gosselet , Cristina Díaz-Perlas , Benjamí Oller-Salvia RSC Chemical Biology, 2023, 5, pp.7 - 11. ⟨10.1039/d3cb00194f⟩ Journal articles hal-04375262v1
	High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro Sasha Soldati , Alexander Bär , Mykhailo Vladymyrov , Dale Glavin , James L Mcgrath Journal of Neuroinflammation, 2023, ⟨10.1186/s12974-023-02797-8⟩ Journal articles hal-04104383v1
	Impact of Pesticide Residues on the Gut-Microbiota–Blood–Brain Barrier Axis: A Narrative Review Maria Abou Diwan , Marwa Lahimer , Véronique Bach , Fabien Gosselet , Hafida Khorsi-Cauet International Journal of Molecular Sciences, 2023, 24 (7), ⟨10.3390/ijms24076147⟩ Journal articles hal-04068149v1
	Synergistic induction of blood-brain barrier properties Gergő Porko , Mária Mészáros , Anikó Szec , Fabien Gosselet , Ricardo Figuei Proceedings of the National Academy of Sciences of the United States of America, 2023, ⟨10.1073/pnas.23160061211of12⟩ Journal articles hal-04597592v1
	Discovery, Structure–Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5 Sylvain Picon , Rajaa Boulahjar , Vanessa Hoguet , Morgane Baron , Isabelle Duplan Journal of Medicinal Chemistry, 2023, ⟨10.1021/acs.jmedchem.2c01881⟩ Journal articles hal-04192205v1
	25-hydroxycholesterol in health and diseases Cindy Nguyen , Julien Saint-Pol , Shiraz Dib , Caroline Pot , Fabien Gosselet Journal of Lipid Research, 2023, ⟨10.1016/j.jlr.2023.100486⟩ Journal articles hal-04352365v1
	Challenges and Opportunities in the Oral Delivery of Recombinant Biologics Solene Masloh , Maxime Culot , Fabien Gosselet , Anne Chevrel , Leonardo Scapozza Pharmaceutics, 2023, 15 (5), ⟨10.3390/pharmaceutics15051415⟩ Journal articles hal-04108844v1
	Differential Blood–Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro Erik Melander , Camilla Eriksson , Sara Wellens , Kimia Hosseini , Robert Fredriksson Pharmaceutics, 2023, 15, ⟨10.3390/pharmaceutics15051507⟩ Journal articles hal-04108846v1
	Highlighting In Vitro the Role of Brain-like Endothelial Cells on the Maturation and Metabolism of Brain Pericytes by SWATH Proteomics Camille Menaceur , Johan Hachani , Shiraz Dib , Sophie Duban-Deweer , Yannis Karamanos Cells, 2023, 12, ⟨10.3390/cells12071010⟩ Journal articles hal-04068135v1
	ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells Julien Cicero , Sarah Trouvilliez , Martine Palma , Gaetan Ternier , Laurine Decoster Experimental Hematology & Oncology, 2023, 12 (1), pp.104. ⟨10.1186/s40164-023-00463-6⟩ Journal articles hal-04334490v1
	TNF-α and IL-1β Modulate Blood-Brain Barrier Permeability and Decrease Amyloid-β Peptide Efflux in a Human Blood-Brain Barrier Model Romain Versele , Emmanuel Sevin , Fabien Gosselet , Laurence Tilloy-Fenart , Pietra Candela International Journal of Molecular Sciences, 2022, 23 (18), pp.10235. ⟨10.3390/ijms231810235⟩ Journal articles hal-03786823v1
	A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning Ophélie da Silva , Nicolas Probst , Christophe Landry , Anne-Sophie Hanak , Pierre Warnault Journal of Medicinal Chemistry, 2022, 65 (6), pp.4649-4666. ⟨10.1021/acs.jmedchem.1c01748⟩ Journal articles hal-03706969v1
	Interaction of surfactant coated PLGA nanoparticles with in vitro human brain-like endothelial cells Elisa L.J. Moya , Sonia Lombardo , Elodie Vandenhaute , Marc Schneider , Caroline Mysiorek International Journal of Pharmaceutics, 2022, 621, pp.121780. ⟨10.1016/j.ijpharm.2022.121780⟩ Journal articles hal-03707013v1
	Pioglitazone Attenuates the Effects of Peripheral Inflammation in a Human In Vitro Blood–Brain Barrier Model Gustavo Henrique Oliveira da Rocha , Rodrigo Azevedo Loiola , Marina de Paula-Silva , Fumitaka Shimizu , Takashi Kanda International Journal of Molecular Sciences, 2022, 23, ⟨10.3390/ijms232112781⟩ Journal articles hal-03851672v1
	Challenges and opportunities in the use of transcriptomics characterization for human iPSC-derived BBB models Sara Wellens , Fabien Gosselet , Maxime Culot Toxicology in Vitro, inPress, ⟨10.1016/j.tiv.2022.105424⟩ Journal articles hal-03708257v2
	The Blood–Brain Barrier, an Evolving Concept Based on Technological Advances and Cell–Cell Communications Camille Menaceur , Fabien Gosselet , Laurence Fenart , Julien Saint-Pol Cells, 2022, 11 (1), pp.133. ⟨10.3390/cells11010133⟩ Journal articles hal-03706905v1
	Quantitative Targeted Absolute Proteomics for Better Characterization of an In Vitro Human Blood–Brain Barrier Model Derived from Hematopoietic Stem Cells Marie-Pierre Dehouck , Masanori Tachikawa , Yutaro Hoshi , Kotaro Omori , Claude-Alain Maurage Cells, 2022, 11 (24), pp.3963. ⟨10.3390/cells11243963⟩ Journal articles hal-03893240v1
	Evaluation of a human iPSC-derived BBB model for repeated dose toxicity testing with cyclosporine A as model compound Sara Wellens , Lucie Dehouck , Vidya Chandrasekaran , Pranika Singh , Rodrigo Azevedo Loiola Toxicology in Vitro, 2021, 73, pp.105112. ⟨10.1016/j.tiv.2021.105112⟩ Journal articles hal-03185595v1
	Potential neurotoxicity of titanium implants: Prospective, in-vivo and in-vitro study Shahar Shelly , Sigal Liraz Zaltsman , Ofir Ben-Gal , Avraham Dayan , Ithamar Ganmore Biomaterials, 2021, 276, pp.121039. ⟨10.1016/j.biomaterials.2021.121039⟩ Journal articles hal-03472462v1
	Transport study of interleukin-1 inhibitors using a human in vitro model of the blood-brain barrier Elisabet Sjöström , Maxime Culot , Lisa Leickt , Mikael Åstrand , Erik Nordling Brain, Behavior & Immunity - Health, 2021, 16, pp.100307. ⟨10.1016/j.bbih.2021.100307⟩ Journal articles hal-03472272v1
	Secretome of endothelial progenitor cells from stroke patients promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage Rodrigo Azevedo Loiola , Miguel García-Gabilondo , Alba Grayston , Paulina Bugno , Agnieszka Kowalska Current Stem Cell Research & Therapy, 2021, 12 (1), ⟨10.1186/s13287-021-02608-y⟩ Journal articles hal-03472260v1
	Beyond the Rule of 5: Impact of PEGylation with Various Polymer Sizes on Pharmacokinetic Properties, Structure–Properties Relationships of mPEGylated Small Agonists of TGR5 Receptor Vanessa Hoguet , Manuel Lasalle , Mathieu Maingot , Geoffroy Dequirez , Rajaa Boulahjar Journal of Medicinal Chemistry, 2021, 64 (3), pp.1593-1610. ⟨10.1021/acs.jmedchem.0c01774⟩ Journal articles hal-03185533v1
	Central nervous system delivery of molecules across the blood-brain barrier Fabien Gosselet , Rodrigo Azevedo Loiola , Anna Roig , Anna Rosell , Maxime Culot Neurochemistry International, 2021, 144, ⟨10.1016/j.neuint.2020.104952⟩ Journal articles hal-03282235v1
	Differential neurovirulence of Usutu viruslineages in mice and neuronal cells Marion Clé , Orianne Constant , Jonathan Barthelemy , Caroline Desmetz , Marie France Martin Journal of Neuroinflammation, 2021, 18 (1), pp.59. ⟨10.1186/s12974-021-02109-y⟩ Journal articles hal-03678372v1
	Time-Dependent Internalization of Polymer-Coated Silica Nanoparticles in Brain Endothelial Cells and Morphological and Functional Effects on the Blood-Brain Barrier Aniela Bittner , Fabien Gosselet , Emmanuel Sevin , Lucie Dehouck , Angélique Ducray International Journal of Molecular Sciences, 2021, 22 (4), pp.1657. ⟨10.3390/ijms22041657⟩ Journal articles hal-03185554v1
	Antimalarial drug discovery: from quinine to the most recent promising clinical drug candidates Camille Tisnerat , Alexandra Dassonville-Klimpt , Fabien Gosselet , Pascal Sonnet Current Medicinal Chemistry, 2021, 28, ⟨10.2174/0929867328666210803152419⟩ Journal articles hal-03472321v1
	Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α—Ve-Cadherin Pathway Daniel Rand , Orly Ravid , Dana Atrakchi , Hila Israelov , Yael Bresler Pharmaceutics, 2021, 13 (3), pp.311. ⟨10.3390/pharmaceutics13030311⟩ Journal articles hal-03185677v1
	Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation Wei Yan , Lingtian Zhang , Fengping Lv , Marialuisa Moccia , Francesca Carlomagno European Journal of Medicinal Chemistry, 2021, 216, pp.113265. ⟨10.1016/j.ejmech.2021.113265⟩ Journal articles hal-03185627v1
	Miniaturization and Automation of a Human In Vitro Blood–Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery Elisa Moya , Elodie Vandenhaute , Eleonora Rizzi , Marie-Christine Boucau , Johan Hachani Pharmaceutics, 2021, 13 (6), pp.892. ⟨10.3390/pharmaceutics13060892⟩ Journal articles hal-03472477v1
	Differential neurovirulence of Usutu virus lineages in mice and neuronal cells Marion Clé , Orianne Constant , Jonathan Barthelemy , Caroline Desmetz , Marie France Martin Journal of Neuroinflammation, 2021, 18 (1), pp.11. ⟨10.1186/s12974-020-02060-4⟩ Journal articles hal-03126852v1
	A Triple Culture Cell System Modeling the Human Blood-Brain Barrier Eleonora Rizzi , Clémence Deligne , Lucie Dehouck , Roberta Bilardo , Yasuteru Sano Journal of visualized experiments : JoVE, 2021, 177, ⟨10.3791/63134⟩ Journal articles hal-03706896v1
	Role of ABCA7 in Human Health and in Alzheimer’s Disease Shiraz Dib , Jens Pahnke , Fabien Gosselet International Journal of Molecular Sciences, 2021, 22 (9), pp.4603. ⟨10.3390/ijms22094603⟩ Journal articles hal-03472487v1
	SARS-CoV-2 Poorly Replicates in Cells of the Human Blood-Brain Barrier Without Associated Deleterious Effects Orianne Constant , Jonathan Barthelemy , Karine Bolloré , Edouard Tuaillon , Fabien Gosselet Frontiers in Immunology, 2021, 12, pp.697329. ⟨10.3389/fimmu.2021.697329⟩ Journal articles hal-03455730v1
	Flow induces barrier and glycocalyx-related genes and negative surface charge in a lab-on-a-chip human blood-brain barrier model Ana R Santa-Maria , Fruzsina R Walter , Ricardo Figueiredo , András Kincses , Judith Vigh Journal of Cerebral Blood Flow and Metabolism, 2021, 41 (9), pp.2201-2215. ⟨10.1177/0271678X21992638⟩ Journal articles hal-03185580v1
	The Effect of Sodium Bicarbonate, a Beneficial Adjuvant Molecule in Cystic Fibrosis, on Bronchial Epithelial Cells Expressing a Wild-Type or Mutant CFTR Channel Ilona Gróf , Alexandra Bocsik , András Harazin , Ana Raquel Santa-Maria , Gaszton Vizsnyiczai International Journal of Molecular Sciences, 2020, 21 (11), pp.4024. ⟨10.3390/ijms21114024⟩ Journal articles hal-03127314v1
	Human CD4+ T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro Hideaki Nishihara , Sasha Soldati , Adrien Mossu , Maria Rosito , Henriette Rudolph Fluids and Barriers of the CNS, 2020, 17, pp.3. ⟨10.1186/s12987-019-0165-2⟩ Journal articles hal-02505269v1
	New Lipidyl-Cyclodextrins Obtained by Ring Opening of Methyl Oleate Epoxide Using Ball Milling Estefania Oliva , David Mathiron , Sébastien Rigaud , Eric Monflier , Emmanuel Sevin Biomolecules, 2020, Perspectives of Cyclodextrins, 10 (2), pp.1-18/339. ⟨10.3390/biom10020339⟩ Journal articles hal-02486048v1
	Serum-derived factors of breast cancer patients with brain metastases alter permeability of a human blood–brain barrier model Carolin Curtaz , Constanze Schmitt , Saskia-Laureen Herbert , Jonas Feldheim , Nicolas Schlegel Fluids and Barriers of the CNS, 2020, 17, pp.31. ⟨10.1186/s12987-020-00192-6⟩ Journal articles hal-03127441v1
	Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells Marjolein Heymans , Ricardo Figueiredo , Lucie Dehouck , David Francisco , Yasuteru Sano Fluids and Barriers of the CNS, 2020, 17 (1), ⟨10.1186/s12987-020-00208-1⟩ Journal articles hal-03127036v1
	Homology Modeling of the Human P-glycoprotein (ABCB1) and Insights into Ligand Binding through Molecular Docking Studies Liadys Mora Lagares , Nikola Minovski , Ana Yisel Caballero Alfonso , Emilio Benfenati , Sara Wellens International Journal of Molecular Sciences, 2020, 21 (11), pp.4058. ⟨10.3390/ijms21114058⟩ Journal articles hal-03127238v1
	Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair Hila Israelov , Orly Ravid , Dana Atrakchi , Daniel Rand , Shirin Elhaik Journal of Neuroinflammation, 2020, 17 (1), ⟨10.1186/s12974-020-01927-w⟩ Journal articles hal-03126925v1
	Chemoselective Hydrogenation of 6‐Alkynyl‐3‐fluoro‐2‐pyridinaldoximes: Access to First‐in‐Class 6‐Alkyl‐3‐Fluoro‐2‐pyridinaldoxime Scaffolds as New Reactivators of Sarin‐Inhibited Human Acetylcholinesterase with Increased Blood–Brain Barrier Permeability Jagadeesh Yerri , José Dias , Mallikajurna Reddy Nimmakayala , Franck Razafindrainibe , Charlotte Courageux Chemistry - A European Journal, 2020, 26 (65), pp.15035-15044. ⟨10.1002/chem.202002012⟩ Journal articles hal-03127205v1
	Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance Clémence Deligne , Johan Hachani , Sophie Duban-Deweer , Samuel Meignan , Pierre Leblond Fluids and Barriers of the CNS, 2020, 17, pp.37. ⟨10.1186/s12987-020-00198-0⟩ Journal articles hal-04461924v1
	Advancing human induced pluripotent stem cell‐derived blood‐brain barrier models for studying immune cell interactions Hideaki Nishihara , Benjamin Gastfriend , Sasha Soldati , Sylvain Perriot , Amandine Mathias FASEB Journal, 2020, 34 (12), pp.16693-16715. ⟨10.1096/fj.202001507RR⟩ Journal articles hal-03126912v1
	Study of Usutu virus neuropathogenicity in mice and human cellular models Marion Clé , Jonathan Barthelemy , Caroline Desmetz , Vincent Foulongne , Lina Lapeyre PLoS Neglected Tropical Diseases, 2020, 14 (4), pp.e0008223. ⟨10.1371/journal.pntd.0008223⟩ Journal articles hal-02886700v1
	Ketone Bodies Promote Amyloid-β1–40 Clearance in a Human in Vitro Blood–Brain Barrier Model Romain Versele , Mariangela Corsi , Andrea Fuso , Emmanuel Sevin , Rita Businaro International Journal of Molecular Sciences, 2020, 21 (3), pp.934. ⟨10.3390/ijms21030934⟩ Journal articles hal-02538226v1
	First step to the improvement of the blood brain barrier passage of atazanavir encapsulated in sustainable bioorganic vesicles Florian Nolay , Emmanuel Sevin , Mathieu Létévé , Abed Bil , Fabien Gosselet International Journal of Pharmaceutics, 2020, 587, pp.119604. ⟨10.1016/j.ijpharm.2020.119604⟩ Journal articles hal-02980826v1
	PLGA protein nanocarriers with tailor-made fluorescence/MRI/PET imaging modalities Yajie Zhang , Miguel García-Gabilondo , Alba Grayston , Irene Feiner , Irene Anton-Sales Nanoscale, 2020, 12 (8), pp.4988-5002. ⟨10.1039/c9nr10620k⟩ Journal articles hal-02538272v1
	GM1 Oligosaccharide Crosses the Human Blood–Brain Barrier In Vitro by a Paracellular Route Erika Di Biase , Giulia Lunghi , Margherita Maggioni , Maria Fazzari , Diego Yuri Pomè International Journal of Molecular Sciences, 2020, 21 (8), pp.2858. ⟨10.3390/ijms21082858⟩ Journal articles hal-03127393v1
	A High Output Method to Isolate Cerebral Pericytes from Mouse Anupriya Mehra , Lucie Dehouck , Elodie Vandenhaute , Marc Fatar , Laurence Fenart Journal of visualized experiments : JoVE, 2020, 155, ⟨10.3791/60588⟩ Journal articles hal-02535814v1
	Naphthoquinone–Dopamine Hybrids Inhibit α‐Synuclein Aggregation, Disrupt Preformed Fibrils, and Attenuate Aggregate‐Induced Toxicity Ashim Paul , Adi Huber , Daniel Rand , Fabien Gosselet , Itzik Cooper Chemistry - A European Journal, 2020, 26 (69), pp.16486-16496. ⟨10.1002/chem.202003374⟩ Journal articles hal-03126960v1
	Nonionotropic Action of Endothelial NMDA Receptors on Blood–Brain Barrier Permeability via Rho/ROCK-Mediated Phosphorylation of Myosin Anupriya Mehra , Sylvaine Guérit , Richard Macrez , Fabien Gosselet , Emmanuel Sevin Journal of Neuroscience, 2020, 40 (8), pp.1778-1787. ⟨10.1523/JNEUROSCI.0969-19.2019⟩ Journal articles hal-02535778v1
	Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime André-Guilhem Calas , Anne-Sophie Hanak , Nina Jaffré , Aurélie Nervo , José Dias Biomolecules, 2020, 10 (6), pp.858. ⟨10.3390/biom10060858⟩ Journal articles hal-03127255v1
	Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles Julien Saint-Pol , Fabien Gosselet , Sophie Duban-Deweer , Gwënaël Pottiez , Yannis Karamanos Cells, 2020, 9 (4), pp.851. ⟨10.3390/cells9040851⟩ Journal articles hal-02538286v1
	Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier Marion Clé , Caroline Desmetz , Jonathan Barthelemy , Marie-France Martin , Orianne Constant mBio, 2020, 11 (4), ⟨10.1128/mBio.01183-20⟩ Journal articles hal-02914994v1
	Transient blood–brain barrier disruption is induced by low pulsed electrical fields in vitro: an analysis of permeability and trans-endothelial electric resistivity Shirley Sharabi , Yael Bresler , Orly Ravid , Chen Shemesh , Dana Atrakchi Drug Delivery, 2019, 26 (1), pp.459-469. ⟨10.1080/10717544.2019.1571123⟩ Journal articles hal-02505306v1
	A Miniaturized Pump Out Method for Characterizing Molecule Interaction with ABC Transporters Emmanuel Sevin , Lucie Dehouck , Romain Versele , Maxime Culot , Fabien Gosselet International Journal of Molecular Sciences, 2019, 20, ⟨10.3390/ijms20225529⟩ Journal articles hal-03282234v1
	Oxysterols and the NeuroVascular Unit (NVU): A far true love with bright and dark sides Julien Saint-Pol , Fabien Gosselet Journal of Steroid Biochemistry and Molecular Biology, 2019, 191 (105368), ⟨10.1016/j.jsbmb.2019.04.017⟩ Journal articles hal-02505516v1
	Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer’s disease-like symptoms in animal model Guru Krishnakumar Viswanathan , Dana Shwartz , Yelena Losev , Elad Arad , Chen Shemesh Cellular and Molecular Life Sciences, 2019, ⟨10.1007/s00018-019-03312-0⟩ Journal articles hal-02505419v1
	PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation Britta Engelhardt , Isabella Wimmer , Silvia Tietz , Hideaki Nishihara , Urban Deutsch Frontiers in Immunology, 2019, 10, pp.711. ⟨10.3389/fimmu.2019.00711⟩ Journal articles hal-02505535v1
	A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood–brain barrier under flow Adrien Mossu , Maria Rosito , Tejas Khire , Hung Li Chung , Hideaki Nishihara Journal of Cerebral Blood Flow and Metabolism, 2018, 39 (3), pp.395-410. ⟨10.1177/0271678X18820584⟩ Journal articles hal-02505603v1
	Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment M.J. Ramalho , Emmanuel Sevin , F. Gosselet , J. Lima , M.A.N. Coelho International Journal of Pharmaceutics, 2018, 545 (1-2), pp.84-92. ⟨10.1016/j.ijpharm.2018.04.062⟩ Journal articles hal-02506188v1
	Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration Marjolein Heymans , Emmanuel Sevin , Fabien Gosselet , Stefan Lundquist , Maxime Culot European Journal of Pharmaceutics and Biopharmaceutics, 2018, 127, pp.453-461. ⟨10.1016/j.ejpb.2018.03.007⟩ Journal articles hal-02506299v1
	Food-Derived Hemorphins Cross Intestinal and Blood–Brain Barriers In Vitro Dorothee Domenger , Benoît Cudennec , Mostafa Kouach , Véronique Touche , Christophe Landry Frontiers in Endocrinology, 2018, 9, pp.159. ⟨10.3389/fendo.2018.00159⟩ Journal articles hal-02506264v1
	Petits mais costauds: Les exosomes neuronaux contrôlent l’intégrité vasculaire cérébrale Julien Saint-Pol , Fabien Gosselet Médecine/Sciences, 2018, 34 (4), pp.303-306. ⟨10.1051/medsci/20183404008⟩ Journal articles hal-02504238v1
	Sodium Transporters Are Involved in Lithium Influx in Brain Endothelial Cells Huilong Luo , Matthieu Gauthier , Xi Tan , Christophe Landry , Joël Poupon Molecular Pharmaceutics, 2018, 15 (7), pp.2528-2538. ⟨10.1021/acs.molpharmaceut.8b00018⟩ Journal articles hal-02506165v1
	ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier Yordenca Lamartinière , Marie-Christine Boucau , Lucie Dehouck , Markus Krohn , Jens Pahnke Journal of Alzheimer's Disease, 2018, 64 (4), pp.1195-1211. ⟨10.3233/JAD-170883⟩ Journal articles hal-02506137v1
	HIV Neuroinfection and Alzheimer’s Disease: Similarities and Potential Links? Geoffrey Canet , Chloé Dias , Audrey Gabelle , Yannick Simonin , Fabien Gosselet Frontiers in Cellular Neuroscience, 2018, 12, ⟨10.3389/fncel.2018.00307⟩ Journal articles hal-02130334v1
	Blood-Brain Barrier Cellular Responses Toward Organophosphates: Natural Compensatory Processes and Exogenous Interventions to Rescue Barrier Properties Orly Ravid , Shirin Elhaik Goldman , David Macheto , Yael Bresler , Raquel Ines de Oliveira Frontiers in Cellular Neuroscience, 2018, 12 (359), ⟨10.3389/fncel.2018.00359⟩ Journal articles hal-02505618v1
	Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer’s Disease Joana Loureiro , Stephanie Andrade , Ana Duarte , Ana Neves , Joana Queiroz Molecules, 2017, 22 (2), pp.277. ⟨10.3390/molecules22020277⟩ Journal articles hal-02506654v1
	ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood–brain barrier Ruth Lyck , Marc-André Lécuyer , Michael Abadier , Christof Wyss , Christoph Matti Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (8), pp.2894-2909. ⟨10.1177/0271678X16678639⟩ Journal articles hal-02506628v1
	Disease-Induced Alterations in Brain Drug Transporters in Animal Models of Alzheimer’s Disease Kati-Sisko Vellonen , Jouni Ihalainen , Marie-Christine Boucau , Fabien Gosselet , Théo Picardat Pharmaceutical Research, 2017, 34 (12), pp.2652-2662. ⟨10.1007/s11095-017-2263-7⟩ Journal articles hal-02506588v1
	Modélisation in vitro de la barrière hémato-encéphalique Fabien Gosselet Médecine/Sciences, 2017, 33 (4), pp.423-431. ⟨10.1051/medsci/20173304013⟩ Journal articles hal-00543630v1
	Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance Manuel Lasalle , Vanessa Hoguet , Nathalie Hennuyer , Florence Leroux , Catherine Piveteau Journal of Medicinal Chemistry, 2017, 60 (10), pp.4185-4211. ⟨10.1021/acs.jmedchem.6b01873⟩ Journal articles inserm-02115415v1
	Pharmacokinetics and In Vitro Blood-Brain Barrier Screening of the Plant-Derived Alkaloid Tryptanthrin Evelyn Jähne , Daniela Eigenmann , Chethan Sampath , Veronika Butterweck , Maxime Culot Planta Medica, 2016, 82 (11/12), pp.1021-1029. ⟨10.1055/s-0042-105295⟩ Journal articles hal-02506889v1
	Cyclodextrins as Emerging Therapeutic Tools in the Treatment of Cholesterol-Associated Vascular and Neurodegenerative Diseases Caroline Coisne , Sébastien Tilloy , Eric Monflier , Daniel Wils , Laurence Fenart Molecules, 2016, 21 (12), pp.1748. ⟨10.3390/molecules21121748⟩ Journal articles hal-01681349v1
	Modulation of Amyloid-β1–40 Transport by ApoA1 and ApoJ Across an in vitro Model of the Blood-Brain Barrier Cristina Merino-Zamorano , Sofía Fernández-de Retana , Alex Montañola , Aina Batlle , Julien Saint-Pol Journal of Alzheimer's Disease, 2016, 53 (2), pp.677-691. ⟨10.3233/JAD-150976⟩ Journal articles hal-02506917v1
	Efficient Docosahexaenoic Acid Uptake by the Brain from a Structured Phospholipid M. Hachem , A. Geloen , A. L. Van , B. Foumaux , L. Fenart Molecular Neurobiology, 2016, 53 (5), pp.3205-3215. ⟨10.1007/s12035-015-9228-9⟩ Journal articles hal-01850313v1
	In vitro blood–brain barrier permeability predictions for GABAA receptor modulating piperine analogs Daniela Elisabeth Eigenmann , Carmen Dürig , Evelyn Andrea Jähne , Martin Smieško , Maxime Culot European Journal of Pharmaceutics and Biopharmaceutics, 2016, 103, pp.118-126. ⟨10.1016/j.ejpb.2016.03.029⟩ Journal articles hal-02510088v1
	Adapting co-culture in vitro models of the blood–brain barrier for use in cancer research: maintaining an appropriate endothelial monolayer for the assessment of transendothelial migration Elodie Vandenhaute , Aurore Drolez , Emmanuel Sevin , Fabien Gosselet , Caroline Mysiorek Laboratory Investigation, 2016, 96 (5), pp.588-598. ⟨10.1038/labinvest.2016.35⟩ Journal articles hal-02510335v1
	In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes Pietra Candela , Julien Saint-Pol , Mélanie Kuntz , Marie-Christine Boucau , Yordenca Lamartinière Brain Research, 2015, 1594, pp.15-26. ⟨10.1016/j.brainres.2014.10.047⟩ Journal articles hal-02513373v1
	Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models Luise Schultz , Marie-Gabrielle Zurich , Maxime Culot , Anaelle da Costa , Christophe Landry Toxicology in Vitro, 2015, 30 (1), pp.138-165. ⟨10.1016/j.tiv.2015.05.016⟩ Journal articles hal-02513335v1
	Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines. Aurore Drolez , Elodie Vandenhaute , Sylvain Julien , Fabien Gosselet , Joy Burchell PLoS ONE, 2015, 11 (3), pp.e0151155. ⟨10.1371/journal.pone.0151155⟩ Journal articles hal-01286618v1
	ST6GALNAC5 Expression Decreases the Interactions between Breast Cancer Cells and the Human Blood-Brain Barrier. Aurore Drolez , Elodie Vandenhaute , Clément Philippe Delannoy , Justine Hélène Dewald , Fabien Gosselet International Journal of Molecular Sciences, 2015, 17 (8), pp.1309. ⟨10.3390/ijms17081309⟩ Journal articles hal-01358166v1
	Bexarotene Promotes Cholesterol Efflux and Restricts Apical-to-Basolateral Transport of Amyloid-β Peptides in an In Vitro Model of the Human Blood-Brain Barrier Mélanie Kuntz , Pietra Candela , Julien Saint-Pol , Yordenca Lamartinière , Marie-Christine Boucau Journal of Alzheimer's Disease, 2015, 48 (3), pp.849-862. ⟨10.3233/JAD-150469⟩ Journal articles hal-02513306v1
	Blood–Brain Barrier Proteomics: Towards the Understanding of Neurodegenerative Diseases Yannis Karamanos , Fabien Gosselet , Marie-Pierre Dehouck , Roméo Cecchelli Archives of Medical Research, 2014, 45 (8), pp.730-737. ⟨10.1016/j.arcmed.2014.11.008⟩ Journal articles hal-02515225v1
	Effects of oxysterols on the blood–brain barrier: Implications for Alzheimer’s disease Fabien Gosselet , Julien Saint-Pol , Laurence Fenart Biochemical and Biophysical Research Communications, 2014, 446 (3), pp.687-691. ⟨10.1016/j.bbrc.2013.11.059⟩ Journal articles hal-02515251v1
	Truncated thioredoxin (Trx-80) promotes pro-inflammatory macrophages of the M1 phenotype and enhances atherosclerosis Dler Faieeq Darweesh Mahmood , Amna Abderrazak , Dominique Couchie , Oleg Lunov , Vimala Diderot Journal of Cellular Physiology, 2013, 228 (7), pp.1577-1583. ⟨10.1002/jcp.24319⟩ Journal articles hal-01544063v1
	Oxysterols decrease apical-to-basolateral transport of Aß peptides via an ABCB1-mediated process in an in vitro Blood-brain barrier model constituted of bovine brain capillary endothelial cells Julien Saint-Pol , Pietra Candela , Marie-Christine Boucau , Laurence Fenart , Fabien Gosselet Brain Research, 2013, 1517, pp.1-15. ⟨10.1016/j.brainres.2013.04.008⟩ Journal articles hal-02515669v1
	The LXR/RXR Approaches in Alzheimer’s Disease: Is the Blood-Bra in Barrier the Forgotten Partner? Julien Saint-Pol , Pietra Candela , Laurence Fenart , Fabien Gosselet Journal of Alzheimer’s Disease & Parkinsonism, 2013, 03 (04), ⟨10.4172/2161-0460.1000e131⟩ Journal articles hal-02515301v1
	Brain pericytes from stress-susceptible pigs increase blood-brain barrier permeability in vitro. Elodie Vandenhaute , Maxime Culot , Fabien Gosselet , Lucie Dehouck , Catherine Godfraind Fluids and Barriers of the CNS, 2012, 9 (1), pp.11. ⟨10.1186/2045-8118-9-11⟩ Journal articles inserm-00714318v1
	Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood-brain barrier: Use of an in vitro model Fabien Gosselet , Pietra Candela , Emmanuel Sevin , Vincent Berezowski , Roméo Cecchelli Brain Research, 2009, 1249, p. 34-42 Journal articles hal-00543674v1
	Physiological pathway for low density lipoproteins across the blood-brain barrier: transcytosis through brain capillary endothelial cells in vitro Pietra Candela , Fabien Gosselet , Florence Miller , Valérie Buée-Scherrer , Gérard Torpier Endothelium, 2008, p. 254-264 Journal articles hal-00543686v1

	Approche intégrée in vitro pour étudier l’impact des pesticides sur l’axe microbiote-intestin-cerveau Maria Abou Diwan , Stéphane Delanaud , Emmanuel Sevin , Aurélie Corona , Fabien Gosselet Colloque commun ARET-SFTG-STCM : Exposome en Toxicologie : du concept à la stratégie d’évaluation des risques, ARET, SFTG et STCM, Oct 2023, Paris, France Conference papers hal-04330230v1
	Alimentation et microbiote en liens avec pesticides et prébiotiques Maria Abou Diwan , Narimane Djekkoun , Claire Joly Condette , Stéphane Delanaud , Emmanuel Sevin Quels systèmes alimentaires pour concilier santé, climat et biodiversité ?, Fondation Evertea – SFSE et le CIRC, Oct 2023, Lyon, France Conference papers hal-04330236v1
	Blood-brain barrier in CNS drug delivery and neurodegenerative diseases Fabien Gosselet Virtual 2nd Symposium on Alzheimer’s Disease: An Update on Pathology and Therapeutics,, Feb 2023, Porto, Portugal Conference papers hal-04335489v1
	Impact de la co-exposition chronique d’un pesticide et du régime obésogène en supplémentation à un prébiotique sur l’axe microbiote-intestin-cerveau chez les rats femelles et leur progéniture Maria Abou Diwan , Narimane Djekkoun , Aurélie Corona , Marie-Christine Boucau , Lucie Dehouck 8ème Journée Amiénoise de Recherche en Santé, UPJV - CHU d'Amiens, Jan 2023, Amiens, France Conference papers hal-04329941v1
	Etude de l’effet d’une co-exposition à un pesticide et aux lipides saturés sur le microbiote intestinal et les propriétés de la barrière hémato-encéphalique Maria Abou Diwan , Narimane Djekkoun , Aurélie Corona , Marie-Christine Boucau , Lucie Dehouck 2ème Journée Diabète et Obésité des Hauts-de-France, Association Copeppi, May 2023, Amiens, France Conference papers hal-04330204v1
	L'exposition chronique péri-gestationnelle au chlorpyrifos ± au régime obésogène entraîne des perturbations du microbiote intestinal et des propriétés de la BHE chez les rats femelles et leur progéniture Maria Abou Diwan , Narimane Djekkoun , Marie-Christine Boucau , Aurélie Corona , Lucie Dehouck Journée annuelle de la Société Cerveau et Maladies cérébrovasculaires (SCMC), Société Cerveau et Maladies cérébrovasculaires (SCMC), Jun 2022, Paris, France Conference papers hal-04329794v1
	L’exposition des rates gestantes au pesticide Chlorpyrifos seul ou en co-exposition avec un régime obésogène module les propriétés de la barrière hémato-encéphalique chez la progéniture Maria Abou Diwan , Lucie Dehouck , Marie-Christine Boucau , Fabien Gosselet , Véronique Bach Exposition précoces aux facteurs environnementaux - Comprendre les impacts et agir sur les écosystèmes et la santé humaine, Société Francophone de Santé et Environnement et Fondation Evertea, Nov 2022, Valence, France Conference papers hal-04329916v1
	Neurotrophins promotes brain metastasis of triple negative breast cancer through Src kinase family activation Julien Cicero , Sarah Trouvilliez , Martine Palma , Gaetan Ternier , Laurine Decoster 1st ONCOLille days 2022, Nov 2022, Lille, France Conference papers hal-03853963v1
	Secretome of endothelial-progenitor cells from stroke patients promotes endothelial barrier tightness and protects against hypoxia-induced vascular damage Fabien Gosselet Virtual Symposium "Signal Transduction at the Blood-Brain Barriers", Sep 2021, Bari, Italy Conference papers hal-04335494v1
	Modelling the blood-brain barrier to investigate amyloid transport in Alzheimer’s disease Fabien Gosselet Victor Babes Meeting 2020, Neuroscience Session, Nov 2020, Bucarest, Romania Conference papers hal-04335497v1
	«Nano-réacteurs à base de cyclodextrines amphiphiles pour la catalyse et la vectorisation» E. Oliva , D. Mathiron , V. Bonnet , S. Pillard , A. Cocq 5ème Séminaire de recherche PIVERT, 2017, Bordeaux, France Conference papers hal-01726466v1
	«Nano-réacteurs à base de cyclodextrines amphiphiles pour la catalyse et la vectorisation» E. Oliva , D. Mathiron , V. Bonnet , S. Pilard , A. Cocq 17èmes Journées Cyclodextrines, 2016, Nancy, France Conference papers hal-01726583v1

	EFFECTS OF PESTICIDES ON THE GUT-MICROBIOTA-BRAIN AXIS ASSESSED BY AN INTEGRATED HUMAN IN VITRO APPROACH Maria Abou Diwan , Avénie Huet , Stéphane Delanaud , Emmanuel Sevin , Aurélie Corona 11th International Conference on Nutrition & Growth, Feb 2024, Lisbon (Portugal), Portugal. Conference poster hal-04475612v1
	Impact de la co-exposition chronique périnatale au pesticide Chlorpyrifos et à un régime obésogène sur l'axe microbiote-intestin-cerveau chez la rate gestante et la progéniture Maria Abou Diwan , Narimane Djekkoun , Aurélie Corona , Marie-Christine Boucau , Lucie Dehouck Les 10 ans de la Fondation Rovaltain, Jun 2023, Valence, France Conference poster hal-04330257v1
	Combinaison de modèles in vivo et in vitro pour étudier la co-exposition des effets chroniques des pesticides et du régime obésogène en supplémentation d’un prébiotique (inuline) sur le microbiote intestinal et sur la barrière hémato-encéphalique chez des populations sensibles Maria Abou Diwan , Narimane Djekkoun , Marie-Christine Boucau , Aurélie Corona , Lucie Dehouck DOCTORIALES, Jun 2022, Belle Dune, Fort-Mahon, France Conference poster hal-04330252v1
	Effect of chronic peri-gestational exposure to chlorpyrifos, alone or in co-exposure with an obesogenic diet on the gut microbiota and the blood-brain barrier Pietra Candela , Maria Abou Diwan , Narimane Djekkoun , Marie-Christine Boucau , Aurélie Corona Journée Scientifique de la Société d’Etudes des Interfaces Sang-Cerveau (SEISC), Nov 2022, Paris, France Conference poster hal-04330253v1
	Interaction of enterovirus A71 with the human blood-brain barrier: an in vitro study Léa Gaume , Hélène Chabrolles , Isabelle Simon , Lucie Dehouck , Fabien Gosselet Société d'études des interfaces Sang Cerveau - SEISC, Nov 2022, Paris, France. Conference poster hal-03877075v1

Fabien GOSSELET

Publications

CD31 orchestrates metabolic regulation in autophagy pathways of rheumatoid arthritis

Enhancing Oral Delivery of Biologics: A Non-Competitive and Cross-Reactive Anti-Leptin Receptor Nanofitin Demonstrates a Gut-Crossing Capacity in an Ex Vivo Porcine Intestinal Model

25-Hydroxycholesterol attenuates tumor necrosis factor alpha-induced blood-brain barrier breakdown in vitro

Secretome of brain microvascular endothelial cells promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage

Enterovirus A71 crosses a human blood–brain barrier model through infected immune cells

Vesicular Trafficking, a Mechanism Controlled by Cascade Activation of Rab Proteins: Focus on Rab27

TNFα Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1

BrainBike peptidomimetic enables efficient transport of proteins across brain endothelium

High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro

Impact of Pesticide Residues on the Gut-Microbiota–Blood–Brain Barrier Axis: A Narrative Review

Synergistic induction of blood-brain barrier properties

Discovery, Structure–Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5

25-hydroxycholesterol in health and diseases

Challenges and Opportunities in the Oral Delivery of Recombinant Biologics

Differential Blood–Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro

Highlighting In Vitro the Role of Brain-like Endothelial Cells on the Maturation and Metabolism of Brain Pericytes by SWATH Proteomics

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells

TNF-α and IL-1β Modulate Blood-Brain Barrier Permeability and Decrease Amyloid-β Peptide Efflux in a Human Blood-Brain Barrier Model

A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning

Interaction of surfactant coated PLGA nanoparticles with in vitro human brain-like endothelial cells

Pioglitazone Attenuates the Effects of Peripheral Inflammation in a Human In Vitro Blood–Brain Barrier Model

Challenges and opportunities in the use of transcriptomics characterization for human iPSC-derived BBB models

The Blood–Brain Barrier, an Evolving Concept Based on Technological Advances and Cell–Cell Communications

Quantitative Targeted Absolute Proteomics for Better Characterization of an In Vitro Human Blood–Brain Barrier Model Derived from Hematopoietic Stem Cells

Evaluation of a human iPSC-derived BBB model for repeated dose toxicity testing with cyclosporine A as model compound

Potential neurotoxicity of titanium implants: Prospective, in-vivo and in-vitro study

Transport study of interleukin-1 inhibitors using a human in vitro model of the blood-brain barrier

Secretome of endothelial progenitor cells from stroke patients promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage

Beyond the Rule of 5: Impact of PEGylation with Various Polymer Sizes on Pharmacokinetic Properties, Structure–Properties Relationships of mPEGylated Small Agonists of TGR5 Receptor

Central nervous system delivery of molecules across the blood-brain barrier

Differential neurovirulence of Usutu viruslineages in mice and neuronal cells

Time-Dependent Internalization of Polymer-Coated Silica Nanoparticles in Brain Endothelial Cells and Morphological and Functional Effects on the Blood-Brain Barrier

Antimalarial drug discovery: from quinine to the most recent promising clinical drug candidates

Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α—Ve-Cadherin Pathway

Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation

Miniaturization and Automation of a Human In Vitro Blood–Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery

Differential neurovirulence of Usutu virus lineages in mice and neuronal cells

A Triple Culture Cell System Modeling the Human Blood-Brain Barrier

Role of ABCA7 in Human Health and in Alzheimer’s Disease

SARS-CoV-2 Poorly Replicates in Cells of the Human Blood-Brain Barrier Without Associated Deleterious Effects

Flow induces barrier and glycocalyx-related genes and negative surface charge in a lab-on-a-chip human blood-brain barrier model

The Effect of Sodium Bicarbonate, a Beneficial Adjuvant Molecule in Cystic Fibrosis, on Bronchial Epithelial Cells Expressing a Wild-Type or Mutant CFTR Channel

Human CD4+ T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro

New Lipidyl-Cyclodextrins Obtained by Ring Opening of Methyl Oleate Epoxide Using Ball Milling

Serum-derived factors of breast cancer patients with brain metastases alter permeability of a human blood–brain barrier model

Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells

Homology Modeling of the Human P-glycoprotein (ABCB1) and Insights into Ligand Binding through Molecular Docking Studies

Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair

Chemoselective Hydrogenation of 6‐Alkynyl‐3‐fluoro‐2‐pyridinaldoximes: Access to First‐in‐Class 6‐Alkyl‐3‐Fluoro‐2‐pyridinaldoxime Scaffolds as New Reactivators of Sarin‐Inhibited Human Acetylcholinesterase with Increased Blood–Brain Barrier Permeability

Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance

Advancing human induced pluripotent stem cell‐derived blood‐brain barrier models for studying immune cell interactions

Study of Usutu virus neuropathogenicity in mice and human cellular models

Ketone Bodies Promote Amyloid-β1–40 Clearance in a Human in Vitro Blood–Brain Barrier Model

First step to the improvement of the blood brain barrier passage of atazanavir encapsulated in sustainable bioorganic vesicles

PLGA protein nanocarriers with tailor-made fluorescence/MRI/PET imaging modalities

GM1 Oligosaccharide Crosses the Human Blood–Brain Barrier In Vitro by a Paracellular Route

A High Output Method to Isolate Cerebral Pericytes from Mouse

Naphthoquinone–Dopamine Hybrids Inhibit α‐Synuclein Aggregation, Disrupt Preformed Fibrils, and Attenuate Aggregate‐Induced Toxicity

Nonionotropic Action of Endothelial NMDA Receptors on Blood–Brain Barrier Permeability via Rho/ROCK-Mediated Phosphorylation of Myosin

Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime

Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles

Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier

Transient blood–brain barrier disruption is induced by low pulsed electrical fields in vitro: an analysis of permeability and trans-endothelial electric resistivity

A Miniaturized Pump Out Method for Characterizing Molecule Interaction with ABC Transporters

Oxysterols and the NeuroVascular Unit (NVU): A far true love with bright and dark sides

Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer’s disease-like symptoms in animal model

PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation

A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood–brain barrier under flow

Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment

Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration

Food-Derived Hemorphins Cross Intestinal and Blood–Brain Barriers In Vitro

Petits mais costauds: Les exosomes neuronaux contrôlent l’intégrité vasculaire cérébrale

Sodium Transporters Are Involved in Lithium Influx in Brain Endothelial Cells

ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier

HIV Neuroinfection and Alzheimer’s Disease: Similarities and Potential Links?

Blood-Brain Barrier Cellular Responses Toward Organophosphates: Natural Compensatory Processes and Exogenous Interventions to Rescue Barrier Properties

Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer’s Disease

ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood–brain barrier