Fabienne MEGGETTO

Publications

Article dans une revue (27)

A strong internal promoter drives massive expression of YEATS‐domain devoid MLLT3 transcripts in HSC and most lethal AML Chloé Bessière,Ahmed Zamani,Romain Pfeifer,Sandra Dailhau,Camille Marchetet al. Cancer Communications, 2025, ⟨10.1002/cac2.12650⟩ Article dans une revue hal-04891593v1
Differential prognostic values of the three AKT isoforms in acute myeloid leukemia Eulalie Corre,Cécile Soum,Romain Pfeifer,Chloé Bessière,Sandra Dailhauet al. Scientific Reports, 2024, 14 (1), pp.7070. ⟨10.1038/s41598-024-57578-x⟩ Article dans une revue hal-04746886v1
Brigatinib in ALK-Positive ALCL after Failure of Brentuximab Vedotin Layla Veleanu,Laurence Lamant,David Sibon,Ambroise Marçais,Julie Bruneauet al. New England Journal of Medicine, 2024, 390, pp.2129 - 2130. ⟨10.1056/nejmc2402419⟩ Article dans une revue hal-04755662v1
From normal hematopoiesis to malignancies: Highlights from the 2021 Meeting of the Club Hematopoiesis and Oncogenesis Marie-Bérengère Troadec,Françoise Porteu,Marie-Laure Arcangeli,Adlen Foudi,Dominique Bluteauet al. Bulletin du Cancer, 2023, 110 (3), pp.331-335. ⟨10.1016/j.bulcan.2022.12.013⟩ Article dans une revue hal-04266637v1
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN Steffen Fuchs,Clara Danßmann,Filippos Klironomos,Annika Winkler,Jörg Fallmannet al. Nature Communications, 2023, 14 (1), pp.3936. ⟨10.1038/s41467-023-38747-4⟩ Article dans une revue hal-04746875v1
Generation of full-length circular RNA libraries for Oxford Nanopore long-read sequencing Steffen Fuchs,Loélia Babin,Elissa Andraos,Chloé Bessiere,Semjon Willieret al. PLoS ONE, 2022, 17 (9), pp. e0273253. ⟨10.1371/journal.pone.0273253⟩ Article dans une revue hal-03773269v1
De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells Loélia Babin,Alice Darchen,Elie Robert,Zakia Aid,Rosalie Borryet al. Molecular Cancer, 2022, 21 (1), pp.65. ⟨10.1186/s12943-022-01520-0⟩ Article dans une revue mnhn-03868576v1
A novel leukemic route of mutant NPM1 through nuclear import of the overexpressed long noncoding RNA LONA Morgane Gourvest,Etienne de Clara,Hsin-Chieh Wu,Christian Touriol,Fabienne Meggettoet al. Leukemia, 2021, 35 (10), pp.2784 - 2798. ⟨10.1038/s41375-021-01307-0⟩ Article dans une revue hal-03383458v1
From circRNAs to fusion circRNAs in hematological malignancies Loelia Babin,Elissa Andraos,Steffen Fuchs,Stéphane Pyronnet,Erika Brunetet al. JCI Insight, 2021, 6 (21), ⟨10.1172/jci.insight.151513⟩ Article dans une revue hal-03826890v2
Gene Expression Signature Associated with Clinical Outcome in ALK-Positive Anaplastic Large Cell Lymphoma Daugrois Camille,Bessiere Chloé,Dejean Sébastien,Anton Leberre Véronique,Commes Thérèseet al. Cancers, 2021, 13 (21), ⟨10.3390/cancers13215523⟩ Article dans une revue hal-03450450v1
High Levels of miR-7-5p Potentiate Crizotinib-Induced Cytokilling and Autophagic Flux by Targeting RAF1 in NPM-ALK Positive Lymphoma Cells Domenico Sorrentino,Julie Frentzel,Géraldine Mitou,Rafael B Blasco,Avédis Torossianet al. Cancers, 2020, 12 (10), pp.2951. ⟨10.3390/cancers12102951⟩ Article dans une revue hal-04822934v1
ALK-transformed mature T lymphocytes restore early thymus progenitor features Annabelle Congras,Coralie Hoareau-Aveilla,Nina Caillet,Marie Tosolini,Patrick Villareseet al. Journal of Clinical Investigation, 2020, 130 (12), pp.6395-6408. ⟨10.1172/JCI134990⟩ Article dans une revue hal-03073841v1
ALK-positive histiocytosis associated with chronic lymphocytic leukaemia/small lymphocytic lymphoma: a multitarget response under ibrutinib Charlotte Syrykh,Loic Ysebaert,Sarah Péricart,Solène Evrard,Fabienne Meggettoet al. Virchows Archiv, 2020, ⟨10.1007/s00428-020-02937-y⟩ Article dans une revue hal-03073859v1
Non-Coding RNA Networks in ALK-Positive Anaplastic-Large Cell Lymphoma Stefen Fuchs,J Naderi,Fabienne Meggetto International Journal of Molecular Sciences, 2019, 20 (9), pp.2150. ⟨10.3390/ijms20092150⟩ Article dans une revue hal-02359846v1
MiR-497 suppresses cycle progression through an axis involving CDK6 in ALK-positive cells. Coralie Hoareau-Aveilla,Cathy Quelen,Annabelle Congras,Nina Caillet,Delphine Labourdetteet al. Haematologica, 2019, 104 (2), pp.347-359. ⟨10.3324/haematol.2018.195131⟩ Article dans une revue hal-01951558v1
Doxorubicin-induced loss of DNA topoisomerase II and DNMT1- dependent suppression of MiR-125b induces chemoresistance in ALK-positive cells Annabelle Congras,Nina Caillet,Nouritza Torossian,Cathy Quelen,Camille Daugroiset al. Oncotarget, 2018, 9 (18), ⟨10.18632/oncotarget.24465⟩ Article dans une revue hal-02359856v1
Reversal of microRNA-150 silencing disadvantages crizotinib-resistant NPM-ALK(+) cell growth Coralie Hoareau-Aveilla,Thibaud Valentin,Camille Daugrois,Cathy Quelen,Géraldine Mitouet al. Journal of Clinical Investigation, 2015, 125 (9), pp.3505--3518. ⟨10.1172/JCI78488⟩ Article dans une revue hal-01614947v1
Inhibition of Rac controls NPM-ALK-dependent lymphoma development and dissemination. A. Colomba,Sylvie Giuriato,Emilie Dejean,K. Thornber,Georges Delsolet al. Blood Cancer Journal, 2011, 1 (6), pp.e21. ⟨10.1038/bcj.2011.19⟩ Article dans une revue inserm-00726858v1
A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor. Sophie Chabot,Nabila Jabrane-Ferrat,Karine Bigot,Julie Tabiasco,Alexandra Provostet al. Journal of Experimental Medicine, 2011, 208 (5), pp.973-86. ⟨10.1084/jem.20100810⟩ Article dans une revue hal-00640905v1
Hypoxia-microRNA-16 downregulation induces VEGF expression in anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell lymphomas. E. Dejean,M. H. Renalier,M. Foisseau,X. Agirre,Nicole Josephet al. Leukemia, 2011, epub ahead of print. ⟨10.1038/leu.2011.168⟩ Article dans une revue hal-00611903v1
MiR-29a down-regulation in ALK-positive anaplastic large cell lymphomas contributes to apoptosis blockade through MCL-1 overexpression. Cécile Desjobert,Marie-Hélène Renalier,Julie Bergalet,Emilie Dejean,Nicole Josephet al. Blood, 2011, 117 (24), pp.6627-37. ⟨10.1182/blood-2010-09-301994⟩ Article dans une revue hal-00611908v1
Conditional TPM3-ALK and NPM-ALK transgenic mice develop reversible ALK-positive early B-cell lymphoma/leukemia. Sylvie Giuriato,Marianne Foisseau,Emilie Dejean,Dean W Felsher,Talal Al Saatiet al. Blood, 2010, 115 (20), pp.4061-70. ⟨10.1182/blood-2008-06-163386⟩ Article dans une revue hal-00502987v1
Regulation of DNA polymerase beta by the LMP1 oncoprotein of EBV through the nuclear factor-kappaB pathway. Nathalie Faumont,Christophe Le Clorennec,Pierre Teira,Gauthier Goormachtigh,Jean Collet al. Cancer Research, 2009, 69 (12), pp.5177-85. ⟨10.1158/0008-5472.CAN-08-2866⟩ Article dans une revue hal-00397988v1
Comparative analysis of oncogenic properties and nuclear factor-kappaB activity of latent membrane protein 1 natural variants from Hodgkin's lymphoma's Reed-Sternberg cells and normal B-lymphocytes. Nathalie Faumont,Aurélie Chanut,Alan Benard,Nadine Cogné,Georges Delsolet al. Haematologica, 2009, 94 (3), pp.355-63. ⟨10.3324/haematol.13269⟩ Article dans une revue hal-00397989v1
Development of a Conditional Bioluminescent Transplant Model for TPM3-ALK-Induced Tumorigenesis as a Tool to Validate ALK-Dependent Cancer Targeted Therapy. Sylvie Giuriato,Nathalie Faumont,Emilie Bousquet,Marianne Foisseau,Anne Bibonneet al. Cancer Biology and Therapy, 2007, 6 (8), pp.1318-23. ⟨10.4161/cbt.6.8.4508⟩ Article dans une revue hal-00170626v1
Human Monocytic Cell Lines Transformed In Vitro by Epstein-Barr Virus Display a Type II Latency and LMP-1-Dependent Proliferation Eric Masy,Eric Adriaenssens,Claire Montpellier,Pascale Crépieux,Alexandra Mougelet al. Journal of Virology, 2002, 76 (13), pp.6460-6472. ⟨10.1128/jvi.76.13.6460-6472.2002⟩ Article dans une revue hal-03104020v1
Evidence for early infection of nonneoplastic natural killer cells by Epstein-Barr virus. Pascal Trempat,Julie Tabiasco,Pascale Andre,Nathalie Faumont,Fabienne Meggettoet al. Journal of Virology, 2002, pp.11139-11142. ⟨10.1128/JVI.76.21.11139-11142.2002⟩ Article dans une revue hal-01759549v1

Chapitre d'ouvrage (1)

Identification of Circular RNA Variants by Oxford Nanopore Long-Read Sequencing Chloé Bessière,Fabienne Meggetto,Christine Gaspin,Steffen Fuchs Gene Expression Analysis, 2880, Springer US, pp.49-68, 2025, Methods in Molecular Biology, ⟨10.1007/978-1-0716-4276-4_3⟩ Chapitre d'ouvrage hal-04929130v1