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Fabrice Leclerc

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Présentation

![](https://www.i2bc.paris-saclay.fr/wp-content/uploads/2021/04/Artistic-view-of-a-possible-RNA-world-1024x490.png) CNRS senior scientist (Ph.D. Biochemistry) in the field of RNA bioinformatics at the University Paris Saclay. I develop and apply modeling approaches to understand the structure/function relationships of RNAs (sequence, 2D, and 3D structure). My research interests include RNomics (identification and characterization of non-coding RNA genes), computational enzymology (elucidate the catalysis by self-cleaving ribozymes), docking (model and predict RNA/protein interactions), and fragment-based design of oligonucleotides. [https://www.i2bc.paris-saclay.fr/equipe-rna-sequence-structure-function/](https://www.i2bc.paris-saclay.fr/equipe-rna-sequence-structure-function/ "RNA Sequence, Structure & Function")

Publications

"isaure-chauvot-de-beauchene"
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Color Coding for the Fragment-Based Docking, Design and Equilibrium Statistics of Protein-Binding ssRNAs

Taher Yacoub , Roy González-Alemán , Fabrice Leclerc , Isaure Chauvot de Beauchêne , Yann Ponty
RECOMB 2024 - 28th International Conference of Research in Computational Molecular Biology, Apr 2024, Boston, United States
Communication dans un congrès hal-03816423v3