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Fabrice Leclerc
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Libre accès
4
Documents
Affiliations actuelles
Identifiants chercheurs
- fabrice-leclerc
- ResearcherId : A-5891-2011
- 0000-0002-5641-1525
- Google Scholar : https://scholar.google.fr/citations?user=omB1U-0AAAAJ&hl=fr
- IdRef : 231160992
Présentation
![](https://www.i2bc.paris-saclay.fr/wp-content/uploads/2021/04/Artistic-view-of-a-possible-RNA-world-1024x490.png)
CNRS senior scientist (Ph.D. Biochemistry) in the field of RNA bioinformatics at the University Paris Saclay. I develop and apply modeling approaches to understand the structure/function relationships of RNAs (sequence, 2D, and 3D structure). My research interests include RNomics (identification and characterization of non-coding RNA genes), computational enzymology (elucidate the catalysis by self-cleaving ribozymes), docking (model and predict RNA/protein interactions), and fragment-based design of oligonucleotides.
[https://www.i2bc.paris-saclay.fr/equipe-rna-sequence-structure-function/](https://www.i2bc.paris-saclay.fr/equipe-rna-sequence-structure-function/ "RNA Sequence, Structure & Function")
Publications
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Ribozyme Chemistry: to be or not to be under high pressureChemical Reviews, 2019, 120 (11), pp.4898-4918. ⟨10.1021/acs.chemrev.9b00457⟩
Article dans une revue
hal-02317015v2
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RNA Back and Forth: Looking through Ribozyme and Viroid MotifsViruses, 2019, 11 (3), pp.283. ⟨10.3390/v11030283⟩
Article dans une revue
hal-02104510v1
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From Foundation Stones to Life: Concepts and ResultsElements, 2016, 12 (6), pp.407 - 412. ⟨10.2113/gselements.12.6.407⟩
Article dans une revue
hal-01489685v1
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Self-assembly Controls Self-cleavage of HHR from ASBVd (−): a Combined SANS and Modeling StudyScientific Reports, 2016, 6 (30287), ⟨10.1038/srep30287⟩
Article dans une revue
hal-01357443v1
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