- 1
Fabrice Leclerc
100%
Libre accès
1
Documents
Affiliations actuelles
Identifiants chercheurs
- fabrice-leclerc
- ResearcherId : A-5891-2011
- 0000-0002-5641-1525
- Google Scholar : https://scholar.google.fr/citations?user=omB1U-0AAAAJ&hl=fr
- IdRef : 231160992
Présentation
![](https://www.i2bc.paris-saclay.fr/wp-content/uploads/2021/04/Artistic-view-of-a-possible-RNA-world-1024x490.png)
CNRS senior scientist (Ph.D. Biochemistry) in the field of RNA bioinformatics at the University Paris Saclay. I develop and apply modeling approaches to understand the structure/function relationships of RNAs (sequence, 2D, and 3D structure). My research interests include RNomics (identification and characterization of non-coding RNA genes), computational enzymology (elucidate the catalysis by self-cleaving ribozymes), docking (model and predict RNA/protein interactions), and fragment-based design of oligonucleotides.
[https://www.i2bc.paris-saclay.fr/equipe-rna-sequence-structure-function/](https://www.i2bc.paris-saclay.fr/equipe-rna-sequence-structure-function/ "RNA Sequence, Structure & Function")
Publications
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
- 1
|
Relating conformation, Mg2+ binding, and functional group modification in the hammerhead ribozyme.RNA, 1997, 3 (7), pp.692-6
Article dans une revue
hal-04003668v1
|