Fabrice SONCIN

INSERM Research Director

Documents

Research domains

Cancer Cardiology and cardiovascular system Micro and nanotechnologies/Microelectronics

Publications

	Coculture model of a liver sinusoidal endothelial cell barrier and HepG2/C3a spheroids-on-chip in an advanced fluidic platform Taha Messelmani , Anne Le Goff , Fabrice Soncin , Zied Souguir , Franck Merlier Journal of Bioscience and Bioengineering, 2023, ⟨10.1016/j.jbiosc.2023.10.006⟩ Journal articles hal-04288584v1
	Genes Involved in miRNA Biogenesis Are Not Downregulated in SARS-CoV-2 Infection Nathalie Garnier , Famara Sane , Layal Massara , Fabrice Soncin , Philippe Gosset Viruses, 2023, 15 (5), pp.1177. ⟨10.3390/v15051177⟩ Journal articles hal-04125326v1
	Investigation of the metabolomic crosstalk between liver sinusoidal endothelial cells and hepatocytes exposed to paracetamol using organ-on-chip technology Taha Messelmani , Anne Le Goff , Fabrice Soncin , Françoise Gilard , Zied Souguir Toxicology, 2023, 492, pp.153550. ⟨10.1016/j.tox.2023.153550⟩ Journal articles hal-04212804v1
	IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein Silvia Gaggero , Jonathan Martinez-Fabregas , Adeline Cozzani , Paul Fyfe , Malo Leprohon Science Immunology, 2022, 7 (78), pp.ade5686. ⟨10.1126/sciimmunol.ade5686⟩ Journal articles hal-04276595v1
	The impact of macrophages on endothelial cells is potentiated by cycling hypoxia: Enhanced tumor inflammation and metastasis Victor Delprat , Camille Huart , Olivier Feron , Fabrice Soncin , Carine Michiels Frontiers in Oncology, 2022, 12, ⟨10.3389/fonc.2022.961753⟩ Journal articles hal-04276601v1
	[Letter to editor] Altered microRNA expression in severe COVID‐19: Potential prognostic and pathophysiological role Nathalie Garnier , Kato Pollet , Marie Fourcot , Morgan Caplan , Guillemette Marot Clinical and Translational Medicine, 2022, 12 (6), pp.e899. ⟨10.1002/ctm2.899⟩ Journal articles hal-03700328v1
	EGF repeats of epidermal growth factor‑like domain 7 promote endothelial cell activation and tumor escape from the immune system Sébastien Pinte , Suzanne Delfortrie , Chantal Havet , Gaëlle Villain , Virginie Mattot Oncology Reports, 2022, 47 (1), pp.8. ⟨10.3892/or.2021.8219⟩ Journal articles hal-03436487v1
	Multi-Layered Human Blood Vessels-on-Chip Design Using Double Viscous Finger Patterning Elise Delannoy , Géraldine Tellier , Juliette Cholet , Alice Leroy , A. Treizebre Biomedicines, 2022, 10 (4), pp.797. ⟨10.3390/biomedicines10040797⟩ Journal articles hal-03634227v1
	Characterization of the proteome and metabolome of human liver sinusoidal endothelial-like cells derived from induced pluripotent stem cells Mathieu Danoy , Rachid Jellali , Yannick Tauran , Johanna Bruce , Marjorie Leduc Differentiation, 2021, 120, pp.1-26. ⟨10.1016/j.diff.2021.06.001⟩ Journal articles hal-03288696v1
	EGF repeats of epidermal growth factor‑like domain 7 promote endothelial cell activation and tumor escape from the immune system Sébastien Pinte , Suzanne Delfortrie , Chantal Havet , Gaëlle Villain , Virginie Mattot Oncology Reports, 2021, 47 (1), ⟨10.3892/OR.2021.8219⟩ Journal articles hal-03513942v1
	Collagen suprafibrillar confinement drives the activity of acidic calcium-binding polymers on apatite mineralization Jérémie Silvent , Marc Robin , Camila Bussola Tovani , Yan Wang , Fabrice Soncin Biomacromolecules, 2021, 22 (7), pp.2802-2814. ⟨10.1021/acs.biomac.1c00206⟩ Journal articles hal-03259914v2
	MicroARN en tant que biomarqueurs de la COVID-19 grave S. Menasria , J. Poissy , B. Guerred , M. Caplan , J. Goutay Infectious Diseases Now, 2021, 51 (5), pp.S62-S63. ⟨10.1016/J.IDNOW.2021.06.133⟩ Journal articles hal-03513950v1
	EGFL7 regulates sprouting angiogenesis and endothelial integrity in a human blood vessel model Ryo Usuba , Joris Pauty , Fabrice Soncin , Yukiko Matsunaga Biomaterials, 2019, 197, pp.305 - 316. ⟨10.1016/j.biomaterials.2019.01.022⟩ Journal articles inserm-03806646v1
	Egfl7 Represses the Vasculogenic Potential of Human Endothelial Progenitor Cells Clément D’audigier , Sophie Susen , Adeline Blandinieres , Virginie Mattot , Bruno Saubamea Stem Cell Reviews and Reports, 2018, 14 (1), pp.82-91. ⟨10.1007/s12015-017-9775-8⟩ Journal articles inserm-03806657v1
	MAGP-1 and fibronectin control EGFL7 functions by driving its deposition into distinct endothelial extracellular matrix locations Gaëlle Villain , Etienne Lelievre , Tom Broekelmann , Odile Gayet , Chantal Havet FEBS Journal, 2018, 285 (23), pp.4394 - 4412. ⟨10.1111/febs.14680⟩ Journal articles inserm-03806651v1
	MAGP-1 and fibronectin control EGFL7 functions by driving its deposition into distinct endothelial extracellular matrix locations Gaelle Villain , Etienne Lelievre , Tom Broekelmann , Odile Gayet , Chantal Havet FEBS Journal, 2018, 285 (23), pp.4394-4412. ⟨10.1111/febs.14680⟩ Journal articles hal-02143593v1
	Egfl7 Represses the Vasculogenic Potential of Human Endothelial Progenitor Cells Clément D’audigier , Sophie Susen , Adeline Blandinieres , Virginie Mattot , Bruno Saubamea Stem Cell Reviews and Reports, 2018, 14 (1), pp.82-91. ⟨10.1007/s12015-017-9775-8⟩ Journal articles hal-02404172v1
	A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs Joris Pauty , Ryo Usuba , Irene Gayi Cheng , Louise Hespel , Haruko Takahashi EBioMedicine, 2018, 27, pp.225-236. ⟨10.1016/j.ebiom.2017.12.014⟩ Journal articles hal-01716252v1
	Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses Reem Ghinnagow , Julie de Meester , Luis Javier Cruz , Caroline Aspord , Stéphanie Corgnac OncoImmunology, 2017, 6 (9), pp.e1339855. ⟨10.1080/2162402X.2017.1339855⟩ Journal articles hal-04276618v1
	Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses Reem Ghinnagow , Julie de Meester , Luis Javier Cruz , Caroline Aspord , Stephanie Corgnac OncoImmunology, 2017, 6 (9), pp.e1339855. ⟨10.1080/2162402X.2017.1339855⟩ Journal articles inserm-02436029v1
	miR-126-5p promotes retinal endothelial cell survival through SetD5 regulation in neurons Gaëlle Villain , Loïc Poissonnier , Baraa Noueihed , Gaëlle Bonfils , Jose Carlos Rivera Development (Cambridge, England), 2017, 145 (1), pp.dev156232. ⟨10.1242/dev.156232⟩ Journal articles inserm-03806652v1
	Coexistence of rheumatoid arthritis and TEMPI syndrome: New insight in microangiogenic-related diseases Tristan Pascart , Charles Herbaux , Angélique Lemaire , Fabrice Soncin , Eric Hachulla Joint Bone Spine, 2016, 83 (5), pp.587-588. ⟨10.1016/j.jbspin.2015.06.011⟩ Journal articles hal-04277359v1
	RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non–Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway Fatéméh Dubois , Maureen Keller , Olivier Calvayrac , Fabrice Soncin , Lily Hoa Cancer Research, 2016, 76 (6), pp.1627-1640. ⟨10.1158/0008-5472.CAN-15-1008⟩ Journal articles hal-02037182v1
	Endothelial Cell Activation Is Regulated by Epidermal Growth Factor-like Domain 7 (Egfl7) during Inflammation Sébastien Pinte , Bertrand Caetano , Alexandra Le Bras , Chantal Havet , Gaëlle Villain Journal of Biological Chemistry, 2016, 291 (46), pp.24017-24028. ⟨10.1074/jbc.M116.731331⟩ Journal articles inserm-03809989v1
	High expression levels of egfl7 correlate with low endothelial cell activation in peritumoral vessels of human breast cancer Diane Pannier , Géraldine Philippin-Lauridant , Marie-Christine Baranzelli , Delphine Bertin , Emilie Bogart Oncology Letters, 2016, 12 (2), pp.1422 - 1428. ⟨10.3892/ol.2016.4791⟩ Journal articles inserm-03809992v1
	Egfl7 Is Differentially Expressed in Arteries and Veins during Retinal Vascular Development Loïc Poissonnier , Gaëlle Villain , Fabrice Soncin , Virginie Mattot PLoS ONE, 2014, 9 (3), pp.e90455. ⟨10.1371/journal.pone.0090455⟩ Journal articles hal-04277368v1
	miR126-5p repression of ALCAM and SetD5 in endothelial cells regulates leucocyte adhesion and transmigration Loïc Poissonnier , Gaëlle Villain , Fabrice Soncin , Virginie Mattot Cardiovascular Research, 2014, 102 (3), pp.436-447. ⟨10.1093/cvr/cvu040⟩ Journal articles hal-04277370v1
	Egfl7 promotes tumor escape from immunity Sébastien Pinte , Fabrice Soncin OncoImmunology, 2014, 1 (3), pp.375-376. ⟨10.4161/onci.18964⟩ Journal articles hal-04277380v1
	Expression of Egfl7 correlates with low-grade invasive lesions in human breast cancer Géraldine Philippin-Lauridant , Marie-Christine Baranzelli , Chantal Samson , Charles Fournier , Sébastien Pinte International Journal of Oncology, 2013, 42 (4), pp.1367-1375. ⟨10.3892/ijo.2013.1820⟩ Journal articles hal-04277374v1
	Differential Proteomic Analysis of Human Glioblastoma and Neural Stem Cells Reveals HDGF as a Novel Angiogenic Secreted Factor Suzanne Delfortrie , Sébastien Pinte , Virginie Mattot , Chantal Samson , Gaëlle Villain STEM CELLS, 2012, 30 (5), pp.845-853. ⟨10.1158/0008-5472.CAN-11-1301⟩ Journal articles hal-04277389v1
	Differential Proteomic Analysis of Human Glioblastoma and Neural Stem Cells Reveals HDGF as a Novel Angiogenic Secreted Factor Cecile Thirant , Eva-Maria Galan-Moya , Luiz Gustavo Dubois , Sebastien Pinte , Philippe Chafey STEM CELLS, 2012, 30 (5), pp.845-853. ⟨10.1002/stem.1062⟩ Journal articles hal-01541440v1
	VE-statin/egfl7 Expression in Endothelial Cells Is Regulated by a Distal Enhancer and a Proximal Promoter under the Direct Control of Erg and GATA-2 Alexandra Le Bras , Chantal Samson , Matteo Trentini , Bertrand Caetano , Etienne Lelievre PLoS ONE, 2010, 5 (8), pp.e12156. ⟨10.1371/journal.pone.0012156⟩ Journal articles hal-04277394v1
	Les gènes qui font l'identité endothéliale Alexandra Le Bras , Fabrice Soncin Journal de la Société de Biologie, 2009, 203 (2), pp.125-141. ⟨10.1051/jbio/2009016⟩ Journal articles hal-04277402v1
	A Functional γδTCR/CD3 Complex Distinct from γδT Cells Is Expressed by Human Eosinophils Fanny Legrand , Virginie Driss , Gaëtane Woerly , Sylvie Loiseau , Emmanuel Hermann PLoS ONE, 2009, 4 (6), pp.e5926. ⟨10.1371/journal.pone.0005926⟩ Journal articles hal-04277398v1
	VE-statin/egfl7 regulates vascular elastogenesis by interacting with lysyl oxidases Etienne Lelièvre , Aleksander Hinek , Florea Lupu , Christelle Buquet , Fabrice Soncin EMBO Journal, 2008, 27 (12), pp.1658-1670. ⟨10.1038/emboj.2008.103⟩ Journal articles hal-04277405v1
	Iodine Deficiency Induces a Thyroid Stimulating Hormone-Independent Early Phase of Microvascular Reshaping in the Thyroid Anne-Catherine Gérard , Sylvie Poncin , Bertrand Caetano , Pierre Sonveaux , Jean-Nicolas Audinot American Journal of Pathology, 2008, 172 (3), pp.748-760. ⟨10.2353/ajpath.2008.070841⟩ Journal articles hal-04277408v1
	HIF-2α specifically activates the VE-cadherin promoter independently of hypoxia and in synergy with Ets-1 through two essential ETS-binding sites A Le Bras , F Lionneton , V Mattot , E Lelièvre , B Caetano Oncogene, 2007, 26 (53), pp.7480-7489. ⟨10.1038/sj.onc.1210566⟩ Journal articles hal-04277411v1
	Expression and purification of recombinant vascular endothelialstatin Bertrand Caetano , Fabrice Soncin , Hervé Drobecq Protein Expression and Purification, 2006, 46, pp.136-142 Journal articles hal-00097333v1
	Expression and purification of recombinant vascular endothelial-statin Bertrand Caetano , Hervé Drobecq , Fabrice Soncin Protein Expression and Purification, 2006, 46 (1), pp.136-142. ⟨10.1016/j.pep.2005.07.029⟩ Journal articles hal-04277413v1
	Ets-1 expression promotes epithelial cell transformation by inducing migration, invasion and anchorage-independent growth Jens Claus Hahne , Ali Fuat Okuducu , Annette Kaminski , Alexandra Florin , Fabrice Soncin Oncogene, 2005, 24 (34), pp.5384-5388. ⟨10.1038/sj.onc.1208761⟩ Journal articles hal-04277417v1
	Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration. Tanja Rothhammer , Ina Poser , Fabrice Soncin , Frauke Bataille , Markus Moser Cancer Research, 2005, 65 (2), pp.448-56 Journal articles hal-04277419v1
	The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma T. Rothhammer , J. Hahne , A. Florin , I. Poser , F. Soncin Cellular and Molecular Life Sciences, 2004, 61 (1), pp.118-128. ⟨10.1007/s00018-003-3337-8⟩ Journal articles hal-04277424v1
	Elevated Expression of Heat Shock Factor (HSF) 2A Stimulates HSF1-induced Transcription during Stress Haiying He , Fabrice Soncin , Nicholas Grammatikakis , Youlin Li , Aliki Siganou Journal of Biological Chemistry, 2003, 278 (37), pp.35465-35475. ⟨10.1074/jbc.M304663200⟩ Journal articles hal-04277446v1
	Characterization and functional analysis of the p42Ets-1 variant of the mouse Ets-1 transcription factor Frédéric Lionneton , Etienne Lelièvre , David Baillat , Dominique Stehelin , Fabrice Soncin Oncogene, 2003, 22 (57), pp.9156-9164. ⟨10.1038/sj.onc.1207241⟩ Journal articles hal-04277430v1
	VE-statin, an endothelial repressor of smooth muscle cell migration F. Soncin , V Mattot , F Lionneton , N Spruyt , F Lepretre EMBO Journal, 2003, 22 (21), pp.5700-5711. ⟨10.1093/emboj/cdg549⟩ Journal articles hal-04277434v1
	The Orphan Nuclear Receptor Rev-Erbα Is a Peroxisome Proliferator-activated Receptor (PPAR) γ Target Gene and Promotes PPARγ-induced Adipocyte Differentiation Coralie Fontaine , Guillaume Dubois , Yannick Duguay , Torben Helledie , Ngoc Vu-Dac Journal of Biological Chemistry, 2003, 278 (39), pp.37672-37680. ⟨10.1074/jbc.M304664200⟩ Journal articles hal-04277438v1
	Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2 Fabrice Soncin , Xinfeng Zhang , Boyang Chu , Xiaozhe Wang , Alexzander Asea Biochemical and Biophysical Research Communications, 2003, 303 (2), pp.700-706. ⟨10.1016/s0006-291x(03)00398-x⟩ Journal articles hal-04277451v1
	Ets-1 Regulates fli-1 Expression in Endothelial Cells Etienne Lelièvre , Frédéric Lionneton , Virginie Mattot , Nathalie Spruyt , Fabrice Soncin Journal of Biological Chemistry, 2002, 277 (28), pp.25143-25151. ⟨10.1074/jbc.M201628200⟩ Journal articles hal-04277457v1
	Basal Transcription of the Mouse Sarco(endo)plasmic Reticulum Ca2+-ATPase Type 3 Gene in Endothelial Cells Is Controlled by Ets-1 and Sp1 Lahouaria Hadri , Anne Ozog , Fabrice Soncin , Anne-Marie Lompré Journal of Biological Chemistry, 2002, 277 (39), pp.36471-36478. ⟨10.1074/jbc.M204731200⟩ Journal articles hal-04277454v1
	Expression and Purification of Recombinant Mouse Ets-1 Transcription Factor Frédéric Lionneton , Hervé Drobecq , Fabrice Soncin Protein Expression and Purification, 2001, 21 (3), pp.492-499. ⟨10.1006/prep.2001.1405⟩ Journal articles hal-04277469v1
	Constitutive expression of the DNA-binding domain of Ets1 increases endothelial cell adhesion and stimulates their organization into capillary-like structures Virginie Mattot , Chantal Vercamer , Fabrice Soncin , Thierry Calmels , Christelle Huguet Oncogene, 2000, 19 (6), pp.762-772. ⟨10.1038/sj.onc.1203248⟩ Journal articles hal-04295172v1
	Role of calcium activated kinases and phosphatases in heat shock factor-1 activation. F. Soncin , A Asea , X Zhang , M Stevenson , S Calderwood International Journal of Molecular Medicine, 2000, ⟨10.3892/ijmm.6.6.705⟩ Journal articles hal-04295158v1
	ETS1 lowers capillary endothelial cell density at confluence and induces the expression of VE-cadherin E Lelièvre , V Mattot , P Huber , B Vandenbunder , F. Soncin Oncogene, 2000, 19 (20), pp.2438-2446. ⟨10.1038/sj.onc.1203563⟩ Journal articles hal-04295166v1
	Increase in expression and activity of thrombomodulin in term human syncytiotrophoblast microvilli A. Fazel , A. Vincenot , A. Malassiné , F. Soncin , P. Gaussem Placenta, 1998, 19 (4), pp.261-268. ⟨10.1016/s0143-4004(98)90057-1⟩ Journal articles hal-04295181v1
	Retinoid Receptors Expression in Human Term Placenta: Involvement of RXRα in Retinoid Induced-hCG Secretion J. Guibourdenche , E. Alsat , F. Soncin , Cécile Rochette-Egly , D. Evain-Brion Journal of Clinical Endocrinology and Metabolism, 1998, 83 (4), pp.1384-1387. ⟨10.1210/jcem.83.4.4860⟩ Journal articles hal-04033572v1
	Transcriptional Activity of Heat Shock Factor 1 at 37 oC Is Repressed through Phosphorylation on Two Distinct Serine Residues by Glycogen Synthase Kinase 3α and Protein Kinases Cα and Cζ Boyang Chu , Rong Zhong , Fabrice Soncin , Mary Ann Stevenson , Stuart Calderwood Journal of Biological Chemistry, 1998, 273 (29), pp.18640-18646. ⟨10.1074/jbc.273.29.18640⟩ Journal articles hal-04295174v1
	Retinoid Receptors Expression in Human Term Placenta: Involvement of RXRα in Retinoid Induced-hCG Secretion J. Guibourdenche , E. Alsat , F. Soncin , C. Rochette-Egly , D. Evain-Brion Journal of Clinical Endocrinology and Metabolism, 1998, 83 (4), pp.1384-1387. ⟨10.1210/jcem.83.4.4860⟩ Journal articles hal-04295180v1
	Interaction of Heparin with Human Angiogenin Fabrice Soncin , Daniel Strydom , Robert Shapiro Journal of Biological Chemistry, 1997, 272 (15), pp.9818-9824. ⟨10.1074/jbc.272.15.9818⟩ Journal articles hal-04295188v1
	Interaction of Human Angiogenin with Copper Modulates Angiogenin Binding to Endothelial Cells Fabrice Soncin , Jean-Dominique Guitton , Terence Cartwright , Josette Badet Biochemical and Biophysical Research Communications, 1997, 236 (3), pp.604-610. ⟨10.1006/bbrc.1997.7018⟩ Journal articles hal-01882798v1
	Expression and Purification of Human Heat-Shock Transcription Factor 1 Fabrice Soncin , Robert Prevelige , Stuart Calderwood Protein Expression and Purification, 1997, 9 (1), pp.27-32. ⟨10.1006/prep.1996.0672⟩ Journal articles hal-04295185v1
	Interaction of Human Angiogenin with Copper Modulates Angiogenin Binding to Endothelial Cells Fabrice Soncin , Jean-Dominique Guitton , Terence Cartwright , Josette Badet Biochemical and Biophysical Research Communications, 1997, 236 (3), pp.604-610. ⟨10.1006/bbrc.1997.7018⟩ Journal articles hal-04295194v1
	Reciprocal Effects of Pro-Inflammatory Stimuli and Anti-Inflammatory Drugs on the Activity of Heat Shock Factor-1 in Human Monocytes Fabrice Soncin , Stuart Calderwood Biochemical and Biophysical Research Communications, 1996, 229 (2), pp.479-484. ⟨10.1006/bbrc.1996.1829⟩ Journal articles hal-04295199v1
	Sequential Phosphorylation by Mitogen-activated Protein Kinase and Glycogen Synthase Kinase 3 Represses Transcriptional Activation by Heat Shock Factor-1 Boyang Chu , Fabrice Soncin , Brendan Price , Mary Ann Stevenson , Stuart Calderwood Journal of Biological Chemistry, 1996, 271 (48), pp.30847-30857. ⟨10.1074/jbc.271.48.30847⟩ Journal articles hal-04295201v1
	A cell-surface proteoglycan mediates human adenocarcinoma HT-29 cell adhesion to human angiogenin. F. Soncin , R. Shapiro , J.W. Fett Journal of Biological Chemistry, 1994, 269 (12), pp.8999-9005. ⟨10.1016/S0021-9258(17)37067-9⟩ Journal articles hal-04295205v1
	Angiogenin supports endothelial and fibroblast cell adhesion. F. Soncin Proceedings of the National Academy of Sciences of the United States of America, 1992, 89 (6), pp.2232-2236. ⟨10.1073/pnas.89.6.2232⟩ Journal articles hal-04295210v1
	Angiogenin and endothelial cells Josette Badet , Fabrice Soncin , Denis Barritault Experientia Supplementum, 1992, Angiogenesis, 61, pp.235-238. ⟨10.1007/978-3-0348-7001-6_36⟩ Journal articles hal-01645089v1
	In vivo and in vitro studies of angiogenin--a potent angiogenic factor Josette Badet , Fabrice Soncin , Thé N'Guyen , Denis Barritault Blood Coagulation & Fibrinolysis, 1990, 1 (6), pp.721-724 Journal articles hal-01880791v1
	Specific binding of angiogenin to calf pulmonary artery endothelial cells Josette Badet , Fabrice Soncin , Jean-Dominique Guitton , Olivier Lamare , Terence Cartwright Proceedings of the National Academy of Sciences of the United States of America, 1989, 86, pp.8427 - 8431 Journal articles hal-01880423v1
	Specific binding of angiogenin to calf pulmonary artery endothelial cells. J Badet , F. Soncin , J Guitton , O Lamare , T Cartwright Proceedings of the National Academy of Sciences of the United States of America, 1989, 86 (21), pp.8427-8431. ⟨10.1073/pnas.86.21.8427⟩ Journal articles hal-04295215v1

	Développement d'une "métastase-sur-puce" pour l'étude de l'extravasation au cours du processus métastatique du cancer du sein. Flavie Woesteland , Chann Lagadec , A. Treizebre , Aude Sivery , Fabrice Soncin 15e journées scientifiques cancéropôle nord ouest, May 2023, Deauville, France Conference papers hal-04545671v1
	Adaptation: from molecular dynamics in single cells to organs on-a-chip approaches Dana Simiuc , Francois Anquez , A. Treizebre , Elodie Vandenhaute , Zied Souguir 1st ONCOLille days 2022, Nov 2022, Lille, France Conference papers hal-03853672v1
	Development of liver-on-chip model integrating LSEC barrier and hepatocytes organoids for toxicity application Taha Messelmani , Anne Le Goff , Fabrice Soncin , Zied Souguir , Elodie Vandenhaute The 1st edition of the MicroPhysio conference on "Micro-physiological models: From organoids to organs-on-chip", Apr 2022, Cargese (Corse), France Conference papers hal-04497703v1
	New microfluidic designs for high-throughput analysis of angiogenesis, blood vessel permeability and endothelial activation E. Delannoy , A. Treizebre , F. Soncin 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020, Oct 2020, Online, United States. pp.845-846 Conference papers hal-03467632v1

	Metastasis on-a-chip platform to follow in real-time the extravasation process and collect extravasated cancer cells Aude Sivery , Flavie Woesteland , F. Soncin , Xuefen Le Bourhis , A. Treizebre OncoLille Workshop, Jan 2024, Lille, France Conference poster hal-04547891v1
	Development of a « metastasis-on-a-chip » to monitor extravasation during metastatic process in breast cancer Flavie Woesteland , Aude Sivery , Marie Denoulet , Mathilde Brulé , Anaïs Horochowska 1st ONCOLille Days, Nov 2022, Lille (France), France Conference poster hal-04545669v1

Fabrice SONCIN

Research domains

Publications

Coculture model of a liver sinusoidal endothelial cell barrier and HepG2/C3a spheroids-on-chip in an advanced fluidic platform

Genes Involved in miRNA Biogenesis Are Not Downregulated in SARS-CoV-2 Infection

Investigation of the metabolomic crosstalk between liver sinusoidal endothelial cells and hepatocytes exposed to paracetamol using organ-on-chip technology

IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein

The impact of macrophages on endothelial cells is potentiated by cycling hypoxia: Enhanced tumor inflammation and metastasis

[Letter to editor] Altered microRNA expression in severe COVID‐19: Potential prognostic and pathophysiological role

EGF repeats of epidermal growth factor‑like domain 7 promote endothelial cell activation and tumor escape from the immune system

Multi-Layered Human Blood Vessels-on-Chip Design Using Double Viscous Finger Patterning

Characterization of the proteome and metabolome of human liver sinusoidal endothelial-like cells derived from induced pluripotent stem cells

EGF repeats of epidermal growth factor‑like domain 7 promote endothelial cell activation and tumor escape from the immune system

Collagen suprafibrillar confinement drives the activity of acidic calcium-binding polymers on apatite mineralization

MicroARN en tant que biomarqueurs de la COVID-19 grave

EGFL7 regulates sprouting angiogenesis and endothelial integrity in a human blood vessel model

Egfl7 Represses the Vasculogenic Potential of Human Endothelial Progenitor Cells

MAGP-1 and fibronectin control EGFL7 functions by driving its deposition into distinct endothelial extracellular matrix locations

MAGP-1 and fibronectin control EGFL7 functions by driving its deposition into distinct endothelial extracellular matrix locations

Egfl7 Represses the Vasculogenic Potential of Human Endothelial Progenitor Cells

A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs

Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses

Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses

miR-126-5p promotes retinal endothelial cell survival through SetD5 regulation in neurons

Coexistence of rheumatoid arthritis and TEMPI syndrome: New insight in microangiogenic-related diseases

RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non–Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway

Endothelial Cell Activation Is Regulated by Epidermal Growth Factor-like Domain 7 (Egfl7) during Inflammation

High expression levels of egfl7 correlate with low endothelial cell activation in peritumoral vessels of human breast cancer

Egfl7 Is Differentially Expressed in Arteries and Veins during Retinal Vascular Development

miR126-5p repression of ALCAM and SetD5 in endothelial cells regulates leucocyte adhesion and transmigration

Egfl7 promotes tumor escape from immunity

Expression of Egfl7 correlates with low-grade invasive lesions in human breast cancer

Differential Proteomic Analysis of Human Glioblastoma and Neural Stem Cells Reveals HDGF as a Novel Angiogenic Secreted Factor

Differential Proteomic Analysis of Human Glioblastoma and Neural Stem Cells Reveals HDGF as a Novel Angiogenic Secreted Factor

VE-statin/egfl7 Expression in Endothelial Cells Is Regulated by a Distal Enhancer and a Proximal Promoter under the Direct Control of Erg and GATA-2

Les gènes qui font l'identité endothéliale

A Functional γδTCR/CD3 Complex Distinct from γδT Cells Is Expressed by Human Eosinophils

VE-statin/egfl7 regulates vascular elastogenesis by interacting with lysyl oxidases

Iodine Deficiency Induces a Thyroid Stimulating Hormone-Independent Early Phase of Microvascular Reshaping in the Thyroid

HIF-2α specifically activates the VE-cadherin promoter independently of hypoxia and in synergy with Ets-1 through two essential ETS-binding sites

Expression and purification of recombinant vascular endothelialstatin

Expression and purification of recombinant vascular endothelial-statin

Ets-1 expression promotes epithelial cell transformation by inducing migration, invasion and anchorage-independent growth

Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration.

The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma

Elevated Expression of Heat Shock Factor (HSF) 2A Stimulates HSF1-induced Transcription during Stress

Characterization and functional analysis of the p42Ets-1 variant of the mouse Ets-1 transcription factor

VE-statin, an endothelial repressor of smooth muscle cell migration

The Orphan Nuclear Receptor Rev-Erbα Is a Peroxisome Proliferator-activated Receptor (PPAR) γ Target Gene and Promotes PPARγ-induced Adipocyte Differentiation

Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2

Ets-1 Regulates fli-1 Expression in Endothelial Cells

Basal Transcription of the Mouse Sarco(endo)plasmic Reticulum Ca2+-ATPase Type 3 Gene in Endothelial Cells Is Controlled by Ets-1 and Sp1

Expression and Purification of Recombinant Mouse Ets-1 Transcription Factor

Constitutive expression of the DNA-binding domain of Ets1 increases endothelial cell adhesion and stimulates their organization into capillary-like structures

Role of calcium activated kinases and phosphatases in heat shock factor-1 activation.

ETS1 lowers capillary endothelial cell density at confluence and induces the expression of VE-cadherin

Increase in expression and activity of thrombomodulin in term human syncytiotrophoblast microvilli

Retinoid Receptors Expression in Human Term Placenta: Involvement of RXRα in Retinoid Induced-hCG Secretion

Transcriptional Activity of Heat Shock Factor 1 at 37 oC Is Repressed through Phosphorylation on Two Distinct Serine Residues by Glycogen Synthase Kinase 3α and Protein Kinases Cα and Cζ

Retinoid Receptors Expression in Human Term Placenta: Involvement of RXRα in Retinoid Induced-hCG Secretion

Interaction of Heparin with Human Angiogenin

Interaction of Human Angiogenin with Copper Modulates Angiogenin Binding to Endothelial Cells

Expression and Purification of Human Heat-Shock Transcription Factor 1

Interaction of Human Angiogenin with Copper Modulates Angiogenin Binding to Endothelial Cells

Reciprocal Effects of Pro-Inflammatory Stimuli and Anti-Inflammatory Drugs on the Activity of Heat Shock Factor-1 in Human Monocytes

Sequential Phosphorylation by Mitogen-activated Protein Kinase and Glycogen Synthase Kinase 3 Represses Transcriptional Activation by Heat Shock Factor-1

A cell-surface proteoglycan mediates human adenocarcinoma HT-29 cell adhesion to human angiogenin.

Angiogenin supports endothelial and fibroblast cell adhesion.

Angiogenin and endothelial cells

In vivo and in vitro studies of angiogenin--a potent angiogenic factor

Specific binding of angiogenin to calf pulmonary artery endothelial cells

Specific binding of angiogenin to calf pulmonary artery endothelial cells.

Développement d'une "métastase-sur-puce" pour l'étude de l'extravasation au cours du processus métastatique du cancer du sein.

Adaptation: from molecular dynamics in single cells to organs on-a-chip approaches

Development of liver-on-chip model integrating LSEC barrier and hepatocytes organoids for toxicity application

New microfluidic designs for high-throughput analysis of angiogenesis, blood vessel permeability and endothelial activation

Metastasis on-a-chip platform to follow in real-time the extravasation process and collect extravasated cancer cells

Development of a « metastasis-on-a-chip » to monitor extravasation during metastatic process in breast cancer