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Florence APPARAILLY

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Specific targeting of inflammatory osteoclastogenesis by the probiotic yeast S. boulardii CNCM I-745 reduces bone loss in osteoporosis

Maria Bernadette Madel , Julia Halper , Lidia Ibáñez , Lozano Claire , Matthieu Rouleau
eLife, 2023, 12, ⟨10.7554/eLife.82037⟩
Journal articles hal-04068580v1
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miRNA profile at diagnosis predicts treatment outcome in patients with B-chronic lymphocytic leukemia: A FILO study

Isabelle Duroux-Richard , Anne-Laure Gagez , Elina Alaterre , Rémi Letestu , Olfa Khalifa
Frontiers in Immunology, 2022, 13, pp.983771. ⟨10.3389/fimmu.2022.983771⟩
Journal articles hal-03946290v1
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Gender Equity in Academic Rheumatology, Current Status and Potential for Improvement: A Cross-Sectional Study to Inform an EULAR Task Force

Pavel V Ovseiko , Laure Gossec , Laura Andreoli , Uta Kiltz , Leonieke Van Mens
RMD Open, 2022, 8 (2), pp.e002518. ⟨10.1136/rmdopen-2022-002518⟩
Journal articles hal-03879085v1
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'SMASH' recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models

Silvia Hayer , Margriet J Vervoordeldonk , Maria C Denis , Marietta Armaka , Markus Hoffmann
Annals of the Rheumatic Diseases, 2021, pp.annrheumdis-2020-219247. ⟨10.1136/annrheumdis-2020-219247⟩
Journal articles hal-03157626v1
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Mitochondrial MicroRNAs Contribute to Macrophage Immune Functions Including Differentiation, Polarization, and Activation

Isabelle Duroux-Richard , Florence Apparailly , Maroun Khoury
Frontiers in Physiology, 2021, 12, pp.738140. ⟨10.3389/fphys.2021.738140⟩
Journal articles hal-03413128v1
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TNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNFα/TNFR1 signalling regulation in the pathophysiology of TRAPS

Cécile Rittore , Déborah Méchin , Elodie Sanchez , Léa Marinèche , Vuthy Ea
Scientific Reports, 2021, 11, pp.4172. ⟨10.1038/s41598-021-83539-9⟩
Journal articles hal-03145389v1
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Integrative Analysis of Human Macrophage Inflammatory Response Related to Mycobacterium tuberculosis Virulence

Pauline Bade , Fabrizio Simonetti , Stephanie Sans , Patricia Laboudie , Khadija Kissane
Frontiers in Immunology, 2021, 12, pp.668060. ⟨10.3389/fimmu.2021.668060⟩
Journal articles hal-03714483v1
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Differential Accumulation and Activation of Monocyte and Dendritic Cell Subsets in Inflamed Synovial Fluid Discriminates Between Juvenile Idiopathic Arthritis and Septic Arthritis

Maïlys Cren , Nadège Nziza , Aurélia Carbasse , Perrine Mahe , Emilie Dufourcq-Lopez
Frontiers in Immunology, 2020, 11, pp.1716. ⟨10.3389/fimmu.2020.01716⟩
Journal articles hal-02965159v1
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Clinical and Molecular Spectrum of Nonsyndromic Early‐Onset Osteoarthritis

Valentin Ruault , Kevin Yauy , Aurélie Fabre , Mélanie Fradin , Julien Van-Gils
Arthritis & rheumatology, 2020, 72 (10), pp.1689 - 1693. ⟨10.1002/art.41387⟩
Journal articles hal-03714570v1
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Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1

Maria-Bernadette Madel , Lidia Ibáñez , Thomas Ciucci , Julia Halper , Matthieu Rouleau
Journal articles hal-03048183v1

POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4

Elodie Sanchez , Béryl Laplace-Builhé , Frédéric Tran Mau-Them , Eric Richard , Alice Goldenberg
Genetics in Medicine, 2020, 22 (3), pp.547-556. ⟨10.1038/s41436-019-0669-9⟩
Journal articles hal-02549940v1
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Immune Function and Diversity of Osteoclasts in Normal and Pathological Conditions

Maria-Bernadette Madel , Lidia Ibáñez , Abdelilah Wakkach , Teun de Vries , Anna Teti
Frontiers in Immunology, 2019, 10, ⟨10.3389/fimmu.2019.01408⟩
Journal articles hal-02402778v1
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Arthritis sensory and motor scale: predicting functional deficits from the clinical score in collagen-induced arthritis

Anne-Laure Mausset-Bonnefont , Maïlys Cren , Rita Vicente , Julie Quentin , Christian Jorgensen
Arthritis Research and Therapy, 2019, 21 (264), ⟨10.1186/s13075-019-2047-z⟩
Journal articles hal-02397115v1
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MicroRNAs: Key Regulators to Understand Osteoclast Differentiation?

Claire Lozano , Isabelle Duroux-Richard , Hüseyin Firat , Eric Schordan , Florence Apparailly
Frontiers in Immunology, 2019, 10, ⟨10.3389/fimmu.2019.00375⟩
Journal articles hal-02874993v1
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LARP7 variants and further delineation of the Alazami syndrome phenotypic spectrum among primordial dwarfisms: 2 sisters

Marion Imbert-Bouteille , Frédéric Tran Mau Them , Julien Thevenon , Thomas Guignard , Vincent Gatinois
European Journal of Medical Genetics, 2019, 62 (3), pp.161-166. ⟨10.1016/j.ejmg.2018.07.003⟩
Journal articles hal-01845043v1
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Synovial-Fluid miRNA Signature for Diagnosis of Juvenile Idiopathic Arthritis

Nadege Nziza , Eric Jeziorski , Marion Delpont , Maïlys Cren , Hugues Chevassus
Cells, 2019, 8 (12), pp.1521. ⟨10.3390/cells8121521⟩
Journal articles hal-02389053v1
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MicroRNAs in juvenile idiopathic arthritis: can we learn more about pathophysiological mechanisms?

Nadege Nziza , Isabelle Duroux-Richard , Florence Apparailly
Autoimmunity Reviews, 2019, 18 (8), pp.796-804. ⟨10.1016/j.autrev.2019.06.006⟩
Journal articles hal-03024109v1
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MicroRNAs: Fine Tuners of Monocyte Heterogeneity

Isabelle Duroux-Richard , Maxime Robin , Cindy Peillex , Florence Apparailly
Frontiers in Immunology, 2019, 10, pp.2145. ⟨10.3389/fimmu.2019.02145⟩
Journal articles hal-03714574v1
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Advanced microRNA-based cancer diagnostics using amplified time-gated FRET

Xue Qiu , Jingyue Xu , Jiajia Guo , Akram Yahia-Ammar , Nikiforos-Ioannis Kapetanakis
Chemical Science, 2018, 9 (42), pp.8046--8055. ⟨10.1039/c8sc03121e⟩
Journal articles hal-02183316v1

Beneficial Effect of Alcohol Withdrawal on Gut Permeability and Microbial Translocation in Patients with Alcohol Use Disorder

Hélène Donnadieu-Rigole , Nathalie Pansu , Thibault Mura , Stéphanie Pelletier , Régis Alarcon
Alcoholism: Clinical and Experimental Research, 2018, 42 (1), pp.32 - 40. ⟨10.1111/acer.13527⟩
Journal articles hal-01845044v1
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Delivery of miR-146a to Ly6C high Monocytes Inhibits Pathogenic Bone Erosion in Inflammatory Arthritis

Meryem Ammari , Jessy Presumey , Clara Ponsolles , Gautier Roussignol , Christine Roubert
Theranostics, 2018, 8 (21), pp.5972-5985. ⟨10.7150/thno.29313⟩
Journal articles hal-02309187v1

Regenerative medicine: Breaking Prometheus's curse for cartilage regeneration

Florence Apparailly
Nature Reviews Rheumatology, 2017, 13 (9), pp.516 - 518. ⟨10.1038/nrrheum.2017.116⟩
Journal articles hal-01845049v1
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microRNA target prediction programs predict many false positives

Natalia Pinzón , Blaise Li , Laura Martinez , Anna Sergeeva , Jessy Presumey
Genome Research, 2017, 27 (2), pp.234 - 245. ⟨10.1101/gr.205146.116⟩
Journal articles hal-01845045v1

A new autoinflammatory and autoimmune syndrome associated with NLRP1 mutations: NAIAD ( NLRP1- associated autoinflammation with arthritis and dyskeratosis)

Sylvie Grandemange , Elodie Sanchez , Pascale Louis-Plence , Frederic Tran Mau-Them , Didier Bessis
Annals of the Rheumatic Diseases, 2017, 76 (7), pp.1191 - 1198. ⟨10.1136/annrheumdis-2016-210021⟩
Journal articles hal-01796999v1

CRISPR-Cas9: A revolution in genome editing in rheumatic diseases

Isabelle Duroux-Richard , Carine Giovannangeli , Florence Apparailly
Joint Bone Spine, 2017, 84 (1), pp.1 - 4. ⟨10.1016/j.jbspin.2016.09.012⟩
Journal articles hal-01845048v1
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TMEM187-IRAK1 Polymorphisms Associated with Rheumatoid Arthritis Susceptibility in Tunisian and French Female Populations: Influence of Geographic Origin

Olfa Khalifa , Nathalie Balandraud , Nathalie Lambert , Isabelle Auger , Jean Roudier
Journal of Immunology Research, 2017, 2017, pp.1 - 12 / 4915950. ⟨10.1155/2017/4915950⟩
Journal articles hal-01488124v1
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miR-125b and miR-532-3p predict the efficiency of rituximab-mediated lymphodepletion in chronic lymphocytic leukemia patients. A French Innovative Leukemia Organization study.

Anne-Laure Gagez , Isabelle Duroux-Richard , Stéphane Leprêtre , Frédérique Orsini-Piocelle , Rémi Letestu
Haematologica, 2017, 102 (4), pp.746-754. ⟨10.3324/haematol.2016.153189⟩
Journal articles hal-01568353v1

Effects of alcohol withdrawal on monocyte subset defects in chronic alcohol users

Hélène Donnadieu-Rigole , Thibault Mura , Pierre Portales , Isabelle Duroux-Richard , Martine Bouthier
Journal of Leukocyte Biology, 2016, 100 (5), pp.1191 - 1199. ⟨10.1189/jlb.5A0216-060RR⟩
Journal articles hal-01845051v1

Deregulation and therapeutic potential of microRNAs in arthritic diseases

Rita Vicente , Danièle Noël , Yves-Marie Pers , Florence Apparailly , Christian Jorgensen
Nature Reviews Rheumatology, 2016, 12 (4), pp.211 - 220. ⟨10.1038/nrrheum.2015.162⟩
Journal articles hal-01834238v1
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miR-125b controls monocyte adaptation to inflammation through mitochondrial metabolism and dynamics

Isabelle Duroux-Richard , Christine Roubert , Meryem Ammari , Jessy Presumey , Joachim Grün
Blood, 2016, 128 (26), pp.3125-3136. ⟨10.1182/blood-2016-02-697003⟩
Journal articles hal-01818909v1

Erratum: Deregulation and therapeutic potential of microRNAs in arthritic diseases

Rita Vicente , Danièle Noël , Yves-Marie Pers , Florence Apparailly , Christian Jorgensen
Nature Reviews Rheumatology, 2016, 12 (8), pp.496 - 496. ⟨10.1038/nrrheum.2016.119⟩
Journal articles hal-01844606v1
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X-Linked miRNAs Associated with Gender Differences in Rheumatoid Arthritis

Olfa Khalifa , Yves-Marie Pers , Rosanna Ferreira , Audrey Sénéchal , Christian Jorgensen
International Journal of Molecular Sciences, 2016, 17 (11), pp.1852. ⟨10.3390/ijms17111852⟩
Journal articles hal-01815741v1
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MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers

Isabelle Duroux-Richard , Jimena Cuenca , Clara Ponsolles , Alejandro Badilla Piñeiro , Fernando Gonzalez
International Journal of Molecular Sciences, 2015, 16 (8), pp.16953 - 16965. ⟨10.3390/ijms160816953⟩
Journal articles hal-01834583v1

Inhibition of Inflammation and Bone Erosion by RNA Interference-Mediated Silencing of Heterogeneous Nuclear RNP A2/B1 in Two Experimental Models of Rheumatoid Arthritis

Sonja Herman , Anita Fischer , Jessy Presumey , Markus Hoffmann , Marije Koenders
Arthritis & rheumatology, 2015, 67 (9), pp.2536 - 2546. ⟨10.1002/art.39223⟩
Journal articles hal-01845054v1

A4.4 MIR-146A deficiency in LY6C high monocytes contributes to pathogenic bone loss during inflammatory arthritis

M Ammari , Isabelle Duroux-Richard , P Presumey , C Ponsolles , G Roussignol
Annals of the Rheumatic Diseases, 2015, 74 (Suppl 1), pp.A37.2 - A38. ⟨10.1136/annrheumdis-2015-207259.86⟩
Journal articles hal-01834614v1
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Circulating miRNA-125b Is a Potential Biomarker Predicting Response to Rituximab in Rheumatoid Arthritis

Isabelle Duroux-Richard , Yves-Marie Pers , Sylvie Fabre , Meryem Ammari , Dominique Baeten
Mediators of Inflammation, 2014, 2014, pp.1 - 9. ⟨10.1155/2014/342524⟩
Journal articles hal-01845068v1
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High efficiency cell-specific targeting of cytokine activity

Geneviève Garcin , Franciane Paul , Markus Staufenbiel , Yann Bordat , José van Der Heyden
Nature Communications, 2014, 5 (1), ⟨10.1038/ncomms4016⟩
Journal articles hal-01845061v1

Transcriptomic Network Support Distinct Roles of Classical and Non-Classical Monocytes in Human

Kolandaswamy Anbazhagan , Isabelle Duroux-Richard , Christian Jorgensen , Florence Apparailly
International Reviews of Immunology, 2014, 33 (6), pp.470 - 489. ⟨10.3109/08830185.2014.902453⟩
Journal articles hal-01845071v1

E2F transcription factor-1 regulates oxidative metabolism

Emilie Blanchet , Jean-Sébastien Annicotte , Sylviane Lagarrigue , Victor Aguilar , Cyrielle Clapé
Nature Cell Biology, 2011, 13 (9), pp.1146-1152. ⟨10.1038/ncb2309⟩
Journal articles hal-02651296v1
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Therapeutic mesenchymal stem cells in rheumatic diseases: rationale, clinical data and perspectives

David Guérit , Marie Maumus , Florence Apparailly , Christian Jorgensen , Danièle Noël
Clinical Investigation, 2011, 1 (9), pp.1269-1277
Journal articles inserm-00644029v1
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Cytosolic phospholipase A2α gene silencing in monocytes alters development of Th1 responses and reduces autoimmune arthritis

Gabriel Courties , Jessy Presumey , Michel Baron , Virginie Escriou , Peter van Lent
Journal of Translational Medicine, 2010, 8 (Suppl 1), pp.O3. ⟨10.1186/1479-5876-8-S1-O3⟩
Journal articles inserm-00934267v1
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BIK is a novel pro-apoptotic target gene for miR-125b in human monocytes

Isabelle Duroux-Richard , Jessy Presumey , Y Pers , Sylvie Fabre , Charles-Henri Lecellier
Journal of Translational Medicine, 2010, 8 (Suppl 1), pp.P56. ⟨10.1186/1479-5876-8-S1-P56⟩
Journal articles inserm-00668428v1
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Toll-like receptor dependent autoantigens in animal models and humans in use to improve collagen induced arthritis

B Marklein , Z Konthur , T Häupl , M Shlomchik , G Steiner
Journal of Translational Medicine, 2010, 8 (Suppl 1), pp.P53
Journal articles inserm-00622783v1
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miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice.

Cyrielle Clapé , Vanessa Fritz , Corinne Henriquet , Florence Apparailly , Pedro Luis Fernandez
PLoS ONE, 2009, 4 (10), pp.e7542. ⟨10.1371/journal.pone.0007542⟩
Journal articles inserm-00431462v1

Antitumoral Activity and Osteogenic Potential of hATF-Expressing Mesenchymal Stem Cells In A Murine Model of Osteolytic Tumor.

Vanessa Fritz , Danièle Noël , Céline Bouquet , Paule Opolon , Romain Voide
Stem Cells / Stem Cells (Miamisburg), 2008, epub ahead of print. ⟨10.1634/stemcells.2008-0139⟩
Journal articles hal-00315969v1

A comparative study on intra-articular versus systemic gene electrotransfer in experimental arthritis.

Maroun Khoury , Pascal Bigey , Pascale Louis-Plence , Danièle Noël , Hervé Rhinn
The Journal of Gene Medicine, 2006, 8 (8), pp.1027-36. ⟨10.1002/jgm.922⟩
Journal articles inserm-00193122v1

Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor alpha in experimental arthritis.

Maroun Khoury , Pascale Louis-Plence , Virginie Escriou , Danièle Noël , Céline Largeau
Arthritis and Rheumatism, 2006, 54 (6), pp.1867-77. ⟨10.1002/art.21876⟩
Journal articles inserm-00193135v1
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Transcriptional profiles discriminate bone marrow-derived and synovium-derived mesenchymal stem cells.

Farida Djouad , Claire Bony , Thomas Häupl , Gilles Uzé , Najiba Lahlou
Arthritis Research and Therapy, 2005, 7, pp.R1304-15. ⟨10.1186/ar1827⟩
Journal articles inserm-00089978v1