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Florence CASTELLI

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Documents

Publications

Blood Monocyte Phenotype Is A Marker of Cardiovascular Risk in Type 2 Diabetes

Jean-Baptiste Julla , Diane Girard , Marc Diedisheim , Pierre-Jean Saulnier , Bao Tran Vuong
Circulation Research, 2024, 134 (2), pp.189-202. ⟨10.1161/circresaha.123.322757⟩
Article dans une revue hal-04534577v1

Despite similar clinical features metabolomics reveals distinct signatures in insulin resistant and progressively obese minipigs

Imene Bousahba , Jérémie David , Florence A Castelli , Céline Chollet , Sadia Ouzia
Journal of Physiology and Biochemistry, 2023, 79 (2), pp.397-413. ⟨10.1007/s13105-022-00940-2⟩
Article dans une revue hal-03941308v1
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Assessment of local and systemic signature of eosinophilic esophagitis (EoE) in children through multi-omics approaches

Karine Adel-Patient , Florence Campeotto , Marta Grauso , Blanche Guillon , Marco Moroldo
Frontiers in Immunology, 2023, 14, pp.1108895. ⟨10.3389/fimmu.2023.1108895⟩
Article dans une revue hal-04032831v1
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Scaling-up metabolomics: Current state and perspectives

Ghina Hajjar , Millena Cristina Barros Santos , Justine Bertrand-Michel , Cécile Canlet , Florence A Castelli
Trends in Analytical Chemistry, 2023, 167 (20), pp.117225. ⟨10.1016/j.trac.2023.117225⟩
Article dans une revue hal-04188505v1
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Development of an untargeted metabolomics strategy to study the metabolic rewiring of dendritic cells upon lipopolysaccharide activation

Jessica Michieletto , Aurélie Delvaux , Emeline Chu-Van , Christophe Junot , François Fenaille
Metabolites, 2023, 13 (3), pp.311. ⟨10.3390/metabo13030311⟩
Article dans une revue hal-04398640v1
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The Human Meconium Metabolome and Its Evolution during the First Days of Life

Nihel Bekhti , Florence Castelli , Alain Paris , Blanche Guillon , Christophe Junot
Metabolites, 2022, 12 (5), pp.414. ⟨10.3390/metabo12050414⟩
Article dans une revue hal-04008723v1
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Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests

Florence Anne Castelli , Giulio Rosati , Christian Moguet , Celia Fuentes , Jose Marrugo-Ramírez
Analytical and Bioanalytical Chemistry, 2022, 414 (2), pp.759-789. ⟨10.1007/s00216-021-03586-z⟩
Article dans une revue hal-04008349v1

Identification of the Major Degradation Pathways of Selumetinib

Tahar Sif Eddine Bouchema , Maxime Annereau , Victoire Vieillard , Raphael Boquet , Gisele Abreu Coelho
Pharmaceutics, 2022, 14 (12), pp.2651. ⟨10.3390/pharmaceutics14122651⟩
Article dans une revue hal-04415612v1
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Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation

Kenza Nedara , Camille Reinhardt , Emilie Lebraud , Giuseppe Arena , Céline Gracia
Frontiers in Oncology, 2022, 12, pp.958155. ⟨10.3389/fonc.2022.958155⟩
Article dans une revue hal-03866235v1
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Cystine Uptake Inhibition Potentiates Front-Line Therapies In Acute Myeloid Leukemia

Bryann Pardieu , Justine Pasanisi , Frank Ling , Reinaldo Dal Bello , Justine Penneroux
Leukemia, 2022, 36 (6), pp.1585-1595. ⟨10.1038/s41375-022-01573-6⟩
Article dans une revue hal-04053984v1
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Using a multiomics approach to unravel a septic shock specific signature in skeletal muscle

Baptiste Duceau , Michael Blatzer , Jean Bardon , Thibault Chaze , Quentin Giai Gianetto
Scientific Reports, 2022, 12 (1), pp.18776. ⟨10.1038/s41598-022-23544-8⟩
Article dans une revue hal-03996889v1
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Metabolomics in the understanding and management of hepatic encephalopathy

Juliette Pelle , Florence A Castelli , Marika Rudler , Imen Alioua , Benoit Colsch
Analytical Biochemistry, 2021, 636, ⟨10.1016/j.ab.2021.114477⟩
Article dans une revue hal-03981510v1
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The Adipose Microenvironment Dysregulates the Mammary Myoepithelial Cells and Could Participate to the Progression of Breast Cancer

Laetitia Delort , Juliette Cholet , Caroline Decombat , Marion Vermerie , Charles Dumontet
Frontiers in Cell and Developmental Biology, 2021, 8, pp.571948. ⟨10.3389/fcell.2020.571948⟩
Article dans une revue hal-03176039v1
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Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia

Lucille Stuani , Marie Sabatier , Estelle Saland , Guillaume Cognet , Nathalie Poupin
Journal of Experimental Medicine, 2021, 218 (5), pp.e20200924. ⟨10.1084/jem.20200924⟩
Article dans une revue hal-03563454v1
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Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men

Blandine Comte , Stéphanie Monnerie , Marion Brandolini-Bunlon , Cécile Canlet , Florence Castelli
EBioMedicine, 2021, 69, ⟨10.1016/j.ebiom.2021.103440⟩
Article dans une revue hal-03283772v1
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Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism

Xavier Leray , Rossella Conti , Yan Li , Cécile Debacker , Florence Castelli
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (32), pp.e2025315118. ⟨10.1073/pnas.2025315118⟩
Article dans une revue hal-03320088v1

Activation of Vitamin D Receptor Pathway Enhances Differentiating Capacity in Acute Myeloid Leukemia with Isocitrate Dehydrogenase Mutations

Marie Sabatier , Emeline Boet , Sonia Zaghdoudi , Nathan Guiraud , Alexis Hucteau
Cancers, 2021, 13 (20), pp.5243. ⟨10.3390/cancers13205243⟩
Article dans une revue hal-04415805v1
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ProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Alyssa Imbert , Magali Rompais , Mohammed Selloum , Florence Castelli , Emmanuelle Mouton-Barbosa
Scientific Data , 2021, 8 (1), pp.311. ⟨10.1038/s41597-021-01095-3⟩
Article dans une revue pasteur-03453736v1
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The effect of acute moderate-intensity exercise on the serum and fecal metabolomes and the gut microbiota of cross-country endurance athletes

Jose Angel García-Merino , Diego Moreno-Pérez , Emeline Chu Van , Mar Larrosa , Mariangela Tabone
Scientific Reports, 2021, 11 (1), pp.1-12. ⟨10.1038/s41598-021-82947-1⟩
Article dans une revue hal-03321433v1
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Untargeted lipidomics uncovers lipid signatures that distinguish severe from moderate forms of acutely decompensated cirrhosis

Joan Clària , Anna Curto , Richard Moreau , Benoit Colsch , Cristina López-Vicario
Journal of Hepatology, 2021, 75 (5), pp.1116-1127. ⟨10.1016/j.jhep.2021.06.043⟩
Article dans une revue hal-04008385v1
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Assessing the role of amino acids in systemic inflammation and organ failure in patients with ACLF

Giacomo Zaccherini , Ferran Aguilar , Paolo Caraceni , Joan Clària , Juan José Lozano
Journal of Hepatology, 2021, 74 (5), pp.1117-1131. ⟨10.1016/j.jhep.2020.11.035⟩
Article dans une revue hal-03351392v1
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Metabotypes of Pseudomonas aeruginosa Correlate with Antibiotic Resistance, Virulence and Clinical Outcome in Cystic Fibrosis Chronic Infections

Oriane Moyne , Florence Castelli , Dominique J. Bicout , Julien Boccard , Boubou Camara
Metabolites, 2021, 11 (2), ⟨10.3390/metabo11020063⟩
Article dans une revue hal-03146820v1
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Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

Richard Moreau , Joan Clària , Ferran Aguilar , François Fenaille , Juan José Lozano
Journal of Hepatology, 2020, 72 (4), pp.688-701. ⟨10.1016/j.jhep.2019.11.009⟩
Article dans une revue hal-03350315v1
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Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages

Felix Renaudin , Lucie Orliaguet , Florence Castelli , François Fenaille , Aurelie Prignon
Annals of the Rheumatic Diseases, 2020, 79 (11), pp.1506-1514. ⟨10.1136/annrheumdis-2020-217342⟩
Article dans une revue hal-03203907v1

Immune components of early breastmilk: Association with maternal factors and with reported food allergy in childhood

Mikaïl Berdi , Blandine de Lauzon-Guillain , Anne Forhan , Florence Anne Castelli , François Fenaille
Pediatric Allergy and Immunology, 2019, 30 (1), pp.107-116. ⟨10.1111/pai.12998⟩
Article dans une revue hal-02619781v1
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Deep analysis of immune response and metabolic signature in children with food protein induced enterocolitis to cow's milk

Karine Adel-Patient , Guillaume Lezmi , Florence Castelli , Sibylle Blanc , Hervé Bernard
Clinical and Translational Allergy, 2018, 8, ⟨10.1186/s13601-018-0224-9⟩
Article dans une revue hal-02622128v1

Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance

Camila Rubio-Patiño , Jozef P Bossowski , Gian Marco de Donatis , Laura Mondragón , Elodie Villa
Cell Metabolism, 2018, 27 (4), pp.828-842.e7. ⟨10.1016/j.cmet.2018.02.009⟩
Article dans une revue hal-01778379v1
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A novel subfamily of bacterial AAT-fold basic amino acid decarboxylases and functional characterization of its first representative: Pseudomonas aeruginosa LdcA

Diego Carriel , Pierre Simon Garcia , Florence Castelli , Patricia Lamourette , François Fenaille
Genome Biology and Evolution, 2018, 10 (11), pp.3058-3075. ⟨10.1093/gbe/evy228⟩
Article dans une revue hal-01987296v1
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Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia

Héléna Boutzen , Estelle Saland , Clément Larrue , Fabienne de Toni , Lara Gales
Journal of Experimental Medicine, 2016, 213 (4), pp.483-497. ⟨10.1084/jem.20150736⟩
Article dans une revue inserm-02465288v1

The Tumor Antigen Cyclin B1 Hosts Multiple CD4 T Cell Epitopes Differently Recognized by Pre-Existing Naive and Memory Cells in Both Healthy and Cancer Donors

Claire Chevaleyre , Nadine Benhamouda , Emmanuel Favry , Elizabeth Fabre , Anais Mhoumadi
Journal of Immunology, 2015, 195 (4), pp.1891-1901. ⟨10.4049/jimmunol.1402548⟩
Article dans une revue halshs-01457345v1

Hierarchy of CD4 T cell epitopes of the ANRS Lipo5 synthetic vaccine relies on the frequencies of pre-existing peptide-specific T cells in healthy donors.

Florence Anne Castelli , Natacha Szely , Alexis Olivain , Nicoletta Casartelli , Caroline Grygar
Journal of Immunology, 2013, 190 (11), pp.5757-63. ⟨10.4049/jimmunol.1300145⟩
Article dans une revue pasteur-01109463v1

Plasma metabolomics reveal metabolite changes compatible with improved metabolic health after 1-month of a plant-rich dietary intervention

Gaïa Lépine , Marie Tremblay-Franco , François Mariotti , Jérémie David , Marion Courrent
NuGOweek 2023, Sep 2023, Senigallia, Italy
Poster de conférence hal-04211898v1

Analyse du métabolome pulmonaire chez les enfants asthmatiques sévères

Mélanie Briard , Blanche Guillon , Eric Venot , Marta Grauso , François Fenaille
Congrès francophone d’allergologie, Apr 2023, Paris, France. Revue Française d'Allergologie, 63 (3), pp.4, 2023, ⟨10.1016/j.reval.2023.103568⟩
Poster de conférence hal-04276720v1
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Immunostimulation of bovine neonate immune cells : metabolomic and transcriptomic responses

Aude Remot , Guillaume Sallé , Cécile Ferret , Mégane Fernandez , Florence Carreras
Journées d'animation scientifique du département Santé Animale (JAS SA), Oct 2022, Anglet, France
Poster de conférence hal-04172281v1

Integrated Multi-omics of early breast milk constituents

Camilo Broc , Karine Adel-Patient , François Fenaille , Mikaïl Berdi , Eric Venot
Intelligent Systems for Molecular Biology/European Conference on computaional biology, Jul 2021, Virtuel, France
Poster de conférence hal-03739277v1
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INPUT OF DEEP PHENOTYPING IN THE METABOLIC SYNDROME STRATIFICATION

Stéphanie Monnerie , Mélanie Pétéra , Cécile Canlet , Florence Castelli , Benoit Colsch
European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France. , 262 p., 2020, Oral and Poster Abstracts European RMF Metabomeeting 2020
Poster de conférence hal-02505908v1
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From Molecular Profiling to Precision Medicine in Metabolic Syndrome

Blandine Comte , Stéphanie Monnerie , Marion Brandolini-Bunlon , Cécile Canlet , Florence Castelli
15th Annual Conference of the Metabolomics Society (Metabolomics 2019), Jun 2019, La Haye, Netherlands. 300 p., 2019
Poster de conférence hal-02293580v1

Compared to animal proteins, plant proteins induce metabolic reorientations that ensure protein homeostasis and are associated with a reduced high-fat-induced insulin resistance

Sergio Polakof , Gaïa Lépine , Véronique Mathé , Jérémie David , Didier Remond
NuGOweek 2019, Sep 2019, Berne, Switzerland
Poster de conférence hal-04443316v1
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Impaired postprandial skeletal muscle metabolism in a minipig model of insulin resistance: insights from arteriovenous and biopsy-based metabolomics analyses

Marie Tremblay-Franco , Nathalie Poupin , Florence Castelli , Jérémie David , Marianne Jarzaguet
12. Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique RFMF, May 2019, Clermont-Ferrand, France. 168 p., 2019, Livre des résumés
Poster de conférence hal-02285596v1

Exploring the impact of plant protein vs. animal protein-rich diets in men at cardiometabolic risk: insights from plasma metabolome signatures

Gaïa Lépine , Marie Tremblay-Franco , François Mariotti , Jérémie David , Marion Courrent
3rd Nordic Metabolomics Conference, Oct 2023, Trondheim, Norway
Communication dans un congrès hal-04354565v1

Metabolomic analysis of bronchoalveolar lavages from severe asthmatic children

Mélanie Briard , Blanche Guillon , Eric Venot , François Fenaille , Florence A Castelli
European Academy of Allergu and Clinical Immunology Congress 2023, European Academy of Allergu and Clinical Immunology, Jun 2023, Hamburg (D), Germany
Communication dans un congrès hal-04276775v1
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Modelling the muscle metabolic response in anabolic and catabolic states using arterio-venous blood metabolomics profiles

Nathalie Poupin , Florence A Castelli , Emeline Chu-Van , Didier Remond , Dominique Dardevet
8. Conference on Constraint-Based reconstruction and Analysis (COBRA 2022), Sep 2022, Galway, Ireland
Communication dans un congrès hal-03807737v1

YAP protects the eye from uveitic glaucoma by preserving retinal and anterior chamber homeostases

Juliette Bitard , Elodie-Kim Grellier , Sophie Lourdel , Helena Filipe , Annaïg Hamon
ARVO Annual Meeting, May 2021, Virtual meeting, United States. pp.2356
Communication dans un congrès hal-03361191v1
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Insights from metabolomic and molecular signatures to detect, in a blood sample, muscle anabolic resistance associated with catabolic situation. Case model of glucocorticoids effect in mini-pigs

Sergio Polakof , Marie Tremblay-Franco , Nathalie Poupin , Florence Castelli , Jérémie David
Fifth International Congress of Translational Research in Human Nutrition (ICTRHN), Jun 2019, Clermont-Ferrand, France
Communication dans un congrès hal-02154641v1