Florence Legendre Ingénieur de Recherche biologiste en laboratoire, PhD, HDR

Identifiants chercheurs

IdHAL :

florence-legendre

ORCID :

0000-0002-9951-1585

IdRef :

069095922

Présentation

EXPERTISEDevelopment and experimentation of new therapeutic strategies (cellular therapy, cartilage tissue engineering, organoid, siRNA/miRNA, drug testing, mechanical stimuli) for osteoarticular syndromes (osteoarthritis, chondrosarcoma, osteosarcoma) in human and equine health.

EDUCATION, DEGREES AND SCIENTIFIC CAREER	2014 : Habilitation to Supervise Research (HDR), University of Caen Lower Normandy	2014 : University Degree of Experimental Surgery, mammals, ONIRIS, Nantes	2012 : University Degree of Competent Person in Radioprotection, University of Caen Lower Normandy	2010 : University Degree of Animal Experimentation, (Level 1, designer), University of Caen	Since 2007 : Research Engineer in Biology, LMEP unit-EA 3214, renowned MILPAT unit- EA 4652 and thereafter** BIOTARGEN unit-UR 7450, University of Caen Normandy**	2002-2007 : Postdoctoral researcher, LMEP unit - EA 3214, University of Caen.	1998-2002 : PhD in Molecular and Cellular Aspects of Biology, LBTC unit-EA 3214, University of Caen.	2001 : University Degree of Statistics Applied to Biology, Pierre and Marie Curie Paris VI University	2000 : Master of Business Administration, IAE of Caen	1998 : Master of Sciences, specialty Cell Biology, Caen-Rouen University

Publications

Article dans une revue (42)

Long term safety and efficacy of a functionalized nanogel with endothelin-1 and bradykinin receptor antagonist peptides for treatment of osteoarthritis of the metacarpophalangeal and distal interphalangeal joints in horses: a descriptive clinical pilot study Antoinette Terlinden,Sandrine Jacquet,Seng Manivong,Virginie Coudry,Amelie Tallajet al. BMC Veterinary Research, 2026, ⟨10.1186/s12917-026-05368-0⟩ Article dans une revue hal-05582212v1
Mechanical Stimulation of Equine Bone Marrow Mesenchymal Stromal Cell-Derived Cartilage-Like In Vitro Model Triggers Osteoarthritis Features Romain Contentin,Cassie Jehl,Kevin Commenchail,Florence Legendre,Philippe Galéraet al. ACS Biomaterials Science and Engineering, 2025, ⟨10.1021/acsbiomaterials.5c00500⟩ Article dans une revue hal-05131501v1
L’arthrose chez le cheval : des thérapies innovantes Florence Legendre,Frédéric Cassé,Romain Contentin,Lélia Bertoni,Magali Demooret al. L'actu des labos normands en santé équine, 2024, 1, pp.8-9 Article dans une revue hal-04780982v1
Double-blinded, randomized tolerance study of a biologically enhanced Nanogel with endothelin-1 and bradykinin receptor antagonist peptides via intra-articular injection for osteoarthritis treatment in horses Antoinette Terlinden,Sandrine Jacquet,Seng Manivong,Aurélie Cullier,Frédéric Casséet al. BMC Veterinary Research, 2024, 20 (1), pp.547. ⟨10.1186/s12917-024-04352-w⟩ Article dans une revue hal-04867791v1
Early castration in horses does not impact osteoarticular metabolism Marion Rouge,Florence Legendre,Razan Elkhatib,Christelle Delalande,Juliette Cognieet al. International Journal of Molecular Sciences, 2023, 24 (23), pp.16778. ⟨10.3390/ijms242316778⟩ Article dans une revue hal-04312304v1
MiR-4270 acts as a tumor suppressor by directly targeting Bcl-xL in human osteosarcoma cells Clément Veys,Flavie Boulouard,Abderrahim Benmoussa,Manon Jammes,Emilie Brotinet al. Frontiers in Oncology, 2023, 13, ⟨10.3389/fonc.2023.1220459⟩ Article dans une revue hal-04216524v1
Tumor Suppressive Role of miR-342-5p and miR-491-5p in Human Osteosarcoma Cells Clément Veys,Manon Jammes,Françoise Rédini,Laurent Poulain,Christophe Denoyelleet al. Pharmaceuticals, 2022, 15 (3), pp.362. ⟨10.3390/ph15030362⟩ Article dans une revue hal-03638646v1
Functionalized Nanogels with Endothelin-1 and Bradykinin Receptor Antagonist Peptides Decrease Inflammatory and Cartilage Degradation Markers of Osteoarthritis in a Horse Organoid Model of Cartilage Aurélie Cullier,Frédéric Cassé,Seng Manivong,Romain Contentin,Florence Legendreet al. International Journal of Molecular Sciences, 2022, 23 (16), pp.8949. ⟨10.3390/ijms23168949⟩ Article dans une revue hal-03775355v1
Tumor Suppressive Role of miR-342-5p in Human Chondrosarcoma Cells and 3D Organoids Clément Veys,Abderrahim Benmoussa,Romain Contentin,Amandine Duchemin,Emilie Brotinet al. International Journal of Molecular Sciences, 2021, 22 (11), pp.5590. ⟨10.3390/ijms22115590⟩ Article dans une revue hal-04783657v1
Marine Collagen Hydrolysates Downregulate the Synthesis of Pro-Catabolic and Pro-Inflammatory Markers of Osteoarthritis and Favor Collagen Production and Metabolic Activity in Equine Articular Chondrocyte Organoids Bastien Bourdon,Romain Contentin,Frédéric Cassé,Chloé Maspimby,Sarah Oddouxet al. International Journal of Molecular Sciences, 2021, 22 (2), pp.580. ⟨10.3390/ijms22020580⟩ Article dans une revue hal-03114578v1
Evaluation of Allogeneic Bone-Marrow-Derived and Umbilical Cord Blood-Derived Mesenchymal Stem Cells to Prevent the Development of Osteoarthritis in An Equine Model Lélia Bertoni,Sandrine Jacquet,Thomas Branly,Mélanie Desancé,Florence Legendreet al. International Journal of Molecular Sciences, 2021, 22 (5), pp.2499. ⟨10.3390/ijms22052499⟩ Article dans une revue hal-03193164v1
Investigation of equine testis contribution to vitamin D bioactivation Marion Rouge,Razan Elkhatib,Christelle Delalande,Juliette Cognié,Fabrice Reigneret al. Domestic Animal Endocrinology, 2021, 79, pp.106691. ⟨10.1016/j.domaniend.2021.106691⟩ Article dans une revue hal-03478703v1
An experimentally induced osteoarthritis model in horses performed on both metacarpophalangeal and metatarsophalangeal joints: Technical, clinical, imaging, biochemical, macroscopic and microscopic characterization Lélia Bertoni,Sandrine Jacquet,Thomas Branly,Florence Legendre,Mélanie Desancéet al. PLoS ONE, 2020, 15 (6), pp.e0235251. ⟨10.1371/journal.pone.0235251⟩ Article dans une revue hal-02935223v1
Regulation of extracellular matrix synthesis by shell extracts from the marine bivalve Pecten maximus in human articular chondrocytes - Application for cartilage engineering. Mouloud Bouyoucef,Rodolphe Rakic,Tangni Gómez-Leduc,Thomas Latire,Frédéric Marinet al. Marine Biotechnology, 2018, 20 (4), pp.436-450. ⟨10.1007/s10126-018-9807-7⟩ Article dans une revue hal-01861438v1
Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy Mélanie Desancé,Romain Contentin,Lélia Bertoni,Tangni Gómez-Leduc,Thomas Branlyet al. International Journal of Molecular Sciences, 2018, 19 (2), pp.537. ⟨10.3390/ijms19020537⟩ Article dans une revue hal-02186781v1
Characterization and use of Equine Bone Marrow Mesenchymal Stem Cells in Equine Cartilage Engineering. Study of their Hyaline Cartilage Forming Potential when Cultured under Hypoxia within a Biomaterial in the Presence of BMP-2 and TGF-ß1 Thomas Branly,Lélia Bertoni,Romain Contentin,Rodolphe Rakic,Tangni Gómez-Leducet al. Stem Cell Reviews and Reports, 2017, 13 (5), pp.611-630. ⟨10.1007/s12015-017-9748-y⟩ Article dans une revue hal-02186824v1
Hypoxia Is a Critical Parameter for Chondrogenic Differentiation of Human Umbilical Cord Blood Mesenchymal Stem Cells in Type I/III Collagen Sponges Tangni Gómez-Leduc,Mélanie Desancé,Magalie Hervieu,Florence Legendre,David Ollitraultet al. International Journal of Molecular Sciences, 2017, 18 (9), pp.1933. ⟨10.3390/ijms18091933⟩ Article dans une revue hal-02186808v1
Shell extracts of the edible mussel and oyster induce an enhancement of the catabolic pathway of human skin fibroblasts, in vitro Thomas Latire,Florence Legendre,Mouloud Bouyoucef,Frédéric Marin,Franck Carreiraset al. Cytotechnology, 2017, 69 (5), pp.815-829. ⟨10.1007/s10616-017-0096-1⟩ Article dans une revue hal-01588926v1
Enhanced chondrogenesis of bone marrow-derived stem cells by using a combinatory cell therapy strategy with BMP-2/TGF-β1, hypoxia, and COL1A1/HtrA1 siRNAs Florence Legendre,David Ollitrault,Tangni Gómez-Leduc,Mouloud Bouyoucef,Magalie Hervieuet al. Scientific Reports, 2017, 7 (1), pp.3406. ⟨10.1038/s41598-017-03579-y⟩ Article dans une revue hal-02285453v1
RNA Interference and BMP-2 Stimulation Allows Equine Chondrocytes Redifferentiation in 3D-Hypoxia Cell Culture Model: Application for Matrix-Induced Autologous Chondrocyte Implantation Rodolphe Rakic,Bastien Bourdon,Magalie Hervieu,Thomas Branly,Florence Legendreet al. International Journal of Molecular Sciences, 2017, 18 (9), pp.1842. ⟨10.3390/ijms18091842⟩ Article dans une revue hal-02186507v1
Reduced NF- κ B activity is observed in dermal fibroblasts from black-skinned African individuals Nicolas Bigot,Tangni Gómez-Leduc,Magalie Hervieu,Fanny Gallienne,Thierry Oddoset al. Experimental Dermatology, 2016, 25 (5), pp.392-394. ⟨10.1111/exd.12970⟩ Article dans une revue hal-02186862v1
Chondrogenic commitment of human umbilical cord blood-derived mesenchymal stem cells in collagen matrices for cartilage engineering Tangni Gómez-Leduc,Magalie Hervieu,Florence Legendre,Mouloud Bouyoucef,Nicolas Gruchyet al. Scientific Reports, 2016, 6 (1), pp.32786. ⟨10.1038/srep32786⟩ Article dans une revue inserm-02304812v1
In vitro engineering of human 3D chondrosarcoma: a preclinical model relevant for investigations of radiation quality impact Dounia Hamdi,Sofia Barbieri,François Chevalier,Jean-Emmanuel Groetz,Florence Legendreet al. BMC Cancer, 2015, ⟨10.1186/s12885-015-1590-5⟩ Article dans une revue hal-01315021v1
Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells Séverine Cruet-Hennequart,Carole Drougard,Georgina Shaw,Florence Legendre,Magali Demooret al. PLoS ONE, 2015, 10 (4), pp.e0119334. ⟨10.1371/journal.pone.0119334⟩ Article dans une revue hal-03156371v1
BMP-2, hypoxia, and COL1A1/HtrA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes D. Ollitrault,F. Legendre,C. Drougard,M. Briand,H. Benateauet al. Tissue Engineering Part C: Methods, 2015, 21 (2), pp.133-147. ⟨10.1089/ten.tec.2013.0724⟩ Article dans une revue hal-01804715v1
Cartilage tissue engineering: Molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction Magali Demoor,David Ollitrault,Tangni Gómez-Leduc,Mouloud Bouyoucef,Magali Hervieuet al. Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840 (8), pp.2414-2440. ⟨10.1016/j.bbagen.2014.02.030⟩ Article dans une revue (article de synthèse) istex hal-02132064v1
Shell Extracts from the Marine Bivalve Pecten maximus Regulate the Synthesis of Extracellular Matrix in Primary Cultured Human Skin Fibroblasts Thomas Latire,Florence Legendre,Nicolas Bigot,Ludovic Carduner,Sabrina Kelloucheet al. PLoS ONE, 2014, 9 (6), pp.e99931. ⟨10.1371/journal.pone.0099931⟩ Article dans une revue hal-01366292v1
Cartilage tissue engineering: Molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction Magali Demoor,David Ollitrault,Tangni Gomez-Leduc,Mouloud Bouyoucef,Magalie Hervieuet al. Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840 (8), pp.2414-2440. ⟨10.1016/j.bbagen.2014.02.030⟩ Article dans une revue istex hal-04783627v1
Enhanced Hyaline Cartilage Matrix Synthesis in Collagen Sponge Scaffolds by Using siRNA to Stabilize Chondrocytes Phenotype Cultured with Bone Morphogenetic Protein-2 Under Hypoxia Florence Legendre,David Ollitrault,Magalie Hervieu,Catherine Baugé,Laure Maneixet al. Tissue Engineering Part C: Methods, 2013, 19 (7), pp.550-567. ⟨10.1089/ten.TEC.2012.0508⟩ Article dans une revue hal-04199500v1
Deciphering chondrocyte behaviour in matrix-induced autologous chondrocyte implantation to undergo accurate cartilage repair with hyaline matrix M. Demoor,L. Maneix,D. Ollitrault,F. Legendre,E. Duvalet al. Pathologie Biologie, 2012, 60 (3), pp.199-207. ⟨10.1016/j.patbio.2012.03.003⟩ Article dans une revue (article de synthèse) istex hal-04202025v1
Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes Emmanuelle Renard,Benoît Porée,Christos Chadjichristos,Magdalini Kypriotou,Laure Maneixet al. Journal of Molecular Medicine, 2012, 90 (6), pp.649-666. ⟨10.1007/s00109-011-0842-3⟩ Article dans une revue istex hal-03838419v1
Décryptage des signalisations moléculaires contrôlant la différenciation des chondrocytes : retombées pour l’ingénierie tissulaire du cartilage : le projet ANR-TecSan PROMOCART S. Claus,E. Aubert-Foucher,E. Perrier-Groult,C. Bougault,M.-C. Ronzièreet al. Innovation and Research in BioMedical engineering, 2011, 32 (2), pp.95-98. ⟨10.1016/j.irbm.2011.01.015⟩ Article dans une revue (article de synthèse) istex hal-04202120v1
Rhein, the metabolite of diacerhein, reduces the proliferation of osteoarthritic chondrocytes and synoviocytes without inducing apoptosis F. Legendre,A. Heuze,K. Boukerrouche,S. Leclercq,K. Boumedieneet al. Scandinavian Journal of Rheumatology, 2009, 38 (2), pp.104-111. ⟨10.1080/03009740802421996⟩ Article dans une revue hal-04200456v1
Interleukin-1 and Transforming Growth Factor-ß 1 as Crucial Factors in Osteoarthritic Cartilage Metabolism Jean-Pierre Pujol,Christos Chadjichristos,Florence Legendre,Catherine Baugé,Gallic Beauchefet al. Connective Tissue Research, 2009, 49 (3-4), pp.293-297. ⟨10.1080/03008200802148355⟩ Article dans une revue hal-03838453v1
Evaluation of Adhesion, Proliferation, and Functional Differentiation of Dermal Fibroblasts on Glycosaminoglycan-Coated Polysulfone Membranes Joan Attia,Florence Legendre,Quang Trong Nguyen,Catherine Baugé,Karim Boumedieneet al. Tissue Engineering: Parts A, B, and C, 2008, 14 (10), pp.1687-1697. ⟨10.1089/ten.tea.2007.0057⟩ Article dans une revue hal-04200472v1
Interleukin-6 (IL-6) and/or Soluble IL-6 Receptor Down-regulation of Human Type II Collagen Gene Expression in Articular Chondrocytes Requires a Decrease of Sp1·Sp3 Ratio and of the Binding Activity of Both Factors to the COL2A1 Promoter Benoît Porée,Magdalini Kypriotou,Christos Chadjichristos,Gallic Beauchef,Emmanuelle Renardet al. Journal of Biological Chemistry, 2008, 283 (8), pp.4850-4865. ⟨10.1074/jbc.M706387200⟩ Article dans une revue hal-03838464v1
Chondroitin sulfate modulation of matrix and inflammatory gene expression in IL-1β-stimulated chondrocytes – study in hypoxic alginate bead cultures F. Legendre,C. Baugé,R. Roche,A.S. Saurel,J.P. Pujol Osteoarthritis and Cartilage, 2008, 16 (1), pp.105-114. ⟨10.1016/j.joca.2007.05.020⟩ Article dans une revue hal-04200519v1
Interleukin-1β impairment of transforming growth factor β1 signaling by DOWN-REGULATION of transforming growth factor β receptor type II and up-regulation of Smad7 in human articular chondrocytes C. Baugé,F. Legendre,S. Leclercq,J. Elissalde,J. Pujolet al. Arthritis and Rheumatism, 2007, 56 (9), pp.3020-3032. ⟨10.1002/art.22840⟩ Article dans une revue hal-04200583v1
Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways. F Legendre,P Bogdanowicz,G Martin,F Domagala,S Leclercqet al. Clinical and experimental rheumatology, 2007, 25 (4), pp.546-55 Article dans une revue hal-04200554v1
Role of interleukin 6 (IL-6)/IL-6R-induced signal tranducers and activators of transcription and mitogen-activated protein kinase/extracellular. Florence Legendre,Patrick Bogdanowicz,Karim Boumediene,Jean-Pierre Pujol Journal of Rheumatology, 2005, 32 (7), pp.1307-16 Article dans une revue hal-04201771v1
Comparative effects of 2 antioxidants, selenomethionine and epigallocatechin-gallate, on catabolic and anabolic gene expression of articular chondrocytes. Rina Andriamanalijaona,Madeleine Kypriotou,Catherine Baugé,Emmanuelle Renard,Florence Legendreet al. Journal of Rheumatology, 2005, 32 (10), pp.1958-67 Article dans une revue hal-04200629v1
JAK/STAT but Not ERK1/ERK2 Pathway Mediates Interleukin (IL)-6/Soluble IL-6R Down-regulation of Type II Collagen, Aggrecan Core, and Link Protein Transcription in Articular Chondrocytes Florence Legendre,Jayesh Dudhia,Jean-Pierre Pujol,Patrick Bogdanowicz Journal of Biological Chemistry, 2003, 278 (5), pp.2903-2912. ⟨10.1074/jbc.M110773200⟩ Article dans une revue hal-04201804v1

Communication dans un congrès (5)

Injection intra-articulaire d’un nanogel fonctionnalisé combinant des effets mécanique et biologique rémanents contre l’arthrose chez le cheval : étude de tolérance A. Terlinden,Sandrine Jacquet,Aurélie Cullier,Frédéric Cassé,F. Legendreet al. 50ème Journées annuelles de l'AVEF, Nov 2022, Reims, France Communication dans un congrès hal-04004349v1
Study of therapeutic potential of new functionalized nanogels against osteoarthritis by using equine cartilage organoid cultures Aurélie Cullier,Frédéric Cassé,Florence Legendre,Romain Contentin,Seng Manivonget al. Journée Normande de Recherche Biomédicale, Jun 2022, Rouen, France Communication dans un congrès hal-03722806v1
Étude de l’impact des hormones testiculaires sur le métabolisme ostéo-articulaire chez l’espèce équine Marion Rouge,Razan Elkhatib,Christelle Delalande,Juliette Cognie,Fabrice Reigneret al. eCongrès International de la Société d’Andrologie de Langue Française, Société d’Andrologie de Langue Française, Jan 2021, CAEN, France Communication dans un congrès hal-04202823v1
Functionalized Nanohydrogels decrease Inflammatory and Cartilage Degradation Biomarkers in an organoid model of horse cartilage tissue Aurélie Cullier,Romain Contentin,Frédéric Cassé,Florence Legendre,Seng Manivonget al. XXIIIème Journées de l'Ecole Doctorale Normande de Biologie Intégrative Santé et Environnement, May 2021, CAEN, France Communication dans un congrès hal-03229755v1
Characterization and use of equine bone marrow mesenchymal stem cells in horse cartilage engineering Thomas Branly,Magalie Hervieu,Sandrine Jacquet,Lélia Bertoni,Tangni Gómez-Leducet al. World Congress of the Osteoarthritis-Research-Society-International, Osteoarthritis Research Society International (OARSI)., Apr 2014, Paris, France. pp.1, ⟨10.1016/j.joca.2014.02.937⟩ Communication dans un congrès hal-02740012v1

Poster de conférence (11)

Functionalized Nanogel-Bottle Brush mitigates induced degradation in 3D cartilage models Kevin Commenchail,Guillaume Dupuy,Romain Contentin,Line Séguy,Valérie Gaëlle Roullinet al. Journée Normande de la Recherche Biomédicale, Jun 2025, Caen (FR), France Poster de conférence hal-05318287v1
Study of the effects of hybrid nanogels on cartilage οrganoids against equine osteoarthritis Kevin Commenchail,Romain Contentin,Line Séguy,Gaëlle Roullin,Pierre Siroiset al. 26ème journée de l'école doctorale NBise, May 2024, Caen, France Poster de conférence hal-04673542v1
Intra-articular injection of a functionalized nanogel combining prolonged mechanical and biological effects as a treatment for osteoarthritis in the horse: a double-blinded, randomized tolerance study A. Terlinden,Sandrine Jacquet,Aurélie Cullier,Frédéric Cassé,Florence Legendreet al. Journées Normandes de la Recherche Biomédicale, Jun 2022, Rouen, France Poster de conférence hal-04003400v1
Functionalized Nanogels decrease Inflammatory and Cartilage Degradation markers of Osteoarthritis in a horse organoid model of cartilage Aurélie Cullier,Romain Contentin,Frédéric Cassé,Florence Legendre,Seng Manivonget al. International Cartilage Regeneration & joint Preservation Society, Apr 2022, Berlin, Germany Poster de conférence hal-03653007v1
Les hormones stéroïdiennes testiculaires contribuent-elles au métabolisme ostéo-articulaire chez l’espèce équine ? Marion Rouge,Razan Elkhatib,Christelle Delalande,Juliette Cognie,Fabrice Reigneret al. 37ème Congrès de la Société Française d’Endocrinologie, Oct 2021, Le Havre, France Poster de conférence hal-04202815v1
Caractérisation phénotypique des chondrocytes fœtaux humains Manon Godin,Romain Contentin,Bastien Bourdon,Florence Legendre,Arnaud Molinet al. 10ème Assises de Génétique Humaine et Médicale, Jan 2020, Tours, France Poster de conférence hal-02436461v1
Use of therapeutic miRNAs for the treatment of chondrosarcoma Clément Veys,Abderrahim Benmoussa,Romain Contentin,Amandine Duchemin,Emilie Brotinet al. 3rd International Conference on the Long and the Short of Non-Coding RNAs, Jun 2019, Chania, Greece Poster de conférence hal-02188430v1
Improvement of the chondrocyte-specific phenotype upon equine bone marrow mesenchymal stem cell differentiation. Influence of TGF-ß1 or TGF-ß3, associated with BMP-2 and type I collagen siRNAs Romain Contentin,Thomas Branly,Mélanie Desancé,Miranda Concari,Thibaud Jacquelet al. 19ème journées françaises de Biologie de Tissus Minéralisés (SFBTM 2017), 2017, Lyon, France Poster de conférence hal-02294803v1
Caractérisation et différenciation des cellules souches mésenchymateuses (CSM) de la moelle osseuse équine et du sang de cordon ombilical pour des applications en ingénierie du cartilage Thomas Branly,Mélanie Desancé,Lélia Bertoni,Romain Contentin,Rodolphe Rakicet al. 46ème Journées annuelles de l'AVEF, 2017, Paris, France Poster de conférence hal-02294586v1
Characterization and differentiation of equine umbilical cord blood mesenchymal stem cells for cartilage tissue engineering Mélanie Desancé,Lélia Bertoni,Romain Contentin,Thomas Branly,Tangni Gómez-Leducet al. 18ème Journées Française de la Biologie des Tissus Minéralisés, 2016, Nancy, France Poster de conférence hal-03957909v1
P046: Engineering of a 3D cartilage model: study of healthy cartilage exposition during hadrontherapy François Chevalier,Dounia Hamdi,Yannick Saintigny,Florence Legendre,Magali Demooret al. PTCOG 53 - Particle Therapy Co-Operative Group, Jun 2014, Shanghai, China. Poster de conférence hal-04235720v1

Brevet (2)

Procédé d’obtention in vitro ou ex vivo de chondrocytes articulaires différenciés et leurs utilisations Philippe Galéra,David Ollitrault,Florence Legendre,Magali Demoor,Frédéric Mallein-Gerinet al. France, N° de brevet: WO 2012/038668. 2012 Brevet hal-04202789v1
Procédé d’obtention in vitro ou ex vivo de chondrocytes articulaires différenciés et leurs utilisations Philippe Galéra,David Ollitrault,Florence Legendre,Magali Demoor,Frédéric Mallein-Gerinet al. France, N° de brevet: FR2965278. 2012 Brevet hal-04202707v1