Francesca Di Nunzio

Publications

Article dans une revue (36)

Tracking HIV-1 DNA fate from cell culture to humanized mice tissues Jean-Sebastien Diana,Evgeny Tatirovsky,Chiara Tomasini,Céline Cuche,Selen Ayet al. Molecular Therapy Advances, 2026, 34 (1), pp.201690. ⟨10.1016/j.omta.2026.201690⟩ Article dans une revue pasteur-05527218v1
Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle Chiara Tomasini,Céline Cuche,Selen Ay,Maxence Collard,Bin Cuiet al. eLife, 2026, 13, ⟨10.7554/eLife.103725⟩ Article dans une revue pasteur-05117096v3
La capside du VIH-1 Thierry Mourer,Francesca Di Nunzio Médecine/Sciences, 2025, 41 (3), pp.219-222. ⟨10.1051/medsci/2025028⟩ Article dans une revue hal-05001671v1
In vivo HIV-1 nuclear condensates safeguard against cGAS and license reverse transcription Selen Ay,Julien Burlaud-Gaillard,Anastasia Gazi,Yevgeniy Tatirovsky,Céline Cucheet al. EMBO Journal, 2024, ⟨10.1038/s44318-024-00316-w⟩ Article dans une revue pasteur-04826770v1
HIV-Induced CPSF6 Condensates Selen Ay,Francesca Di Nunzio Journal of Molecular Biology, 2023, pp.168094. ⟨10.1016/j.jmb.2023.168094⟩ Article dans une revue pasteur-04126694v1
HIV-induced membraneless organelles orchestrate post-nuclear entry steps Viviana Scoca,Renaud Morin,Maxence Collard,Jean-Yves Tinevez,Francesca Di Nunzio Journal of molecular cell biology, 2023, 14 (11), pp.mjac060. ⟨10.1093/jmcb/mjac060⟩ Article dans une revue hal-04264224v3
Biomolecular condensates: insights into early and late steps of the HIV-1 replication cycle. Francesca Di Nunzio,Vladimir Uversky,Andrew Mouland Retrovirology, 2023, 20 (1), pp.4. ⟨10.1186/s12977-023-00619-6⟩ Article dans une revue pasteur-04126418v1
Stress-induced condensate switch awakens sleeping viruses Francesca Di Nunzio Cell Host & Microbe, 2023, 31 (5), pp.679-680. ⟨10.1016/j.chom.2023.04.008⟩ Article dans une revue pasteur-04126658v1
The Viral Capsid: A Master Key to Access the Host Nucleus Guillermo Blanco-Rodriguez,Francesca Di Nunzio Viruses, 2021, 13 (6), pp.1178. ⟨10.3390/v13061178⟩ Article dans une revue pasteur-03344209v1
Membraneless organelles restructured and built by pandemic viruses: HIV-1 and SARS-CoV-2 Viviana Scoca,Francesca Di Nunzio Journal of molecular cell biology, 2021, ⟨10.1093/jmcb/mjab020⟩ Article dans une revue pasteur-03214326v1
The HIV-1 Capsid: From Structural Component to Key Factor for Host Nuclear Invasion Viviana Scoca,Francesca Di Nunzio Viruses, 2021, 13 (2), pp.273. ⟨10.3390/v13020273⟩ Article dans une revue pasteur-03214327v1
Clustering and reverse transcription of HIV‐1 genomes in nuclear niches of macrophages Elena Rensen,Florian Mueller,Viviana Scoca,Jyotsana Parmar,Philippe Souqueet al. EMBO Journal, 2021, 40 (1), pp.e105247. ⟨10.15252/embj.2020105247⟩ Article dans une revue pasteur-03088393v1
Remodeling of the core leads HIV-1 pre-integration complex in the nucleus of human lymphocytes. Guillermo Blanco-Rodriguez,Anastasia Gazi,Blandine Monel,Stella Frabetti,Viviana Scocaet al. Journal of Virology, 2020, [Epub ahead of print], pp.JVI.00135-20. ⟨10.1128/JVI.00135-20⟩ Article dans une revue pasteur-02548457v1
Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core Anastasia Selyutina,Mirjana Persaud,Lacy Simons,Angel Bulnes-Ramos,Cindy Buffoneet al. Cell Reports, 2020, 30 (11), pp.3766-3777.e6. ⟨10.1016/j.celrep.2020.02.100⟩ Article dans une revue pasteur-03106108v1
Les facteurs du pore nucléaire : un collectif gagnant pour la translocation et l’intégration du VIH-1 François Berry,Pierre Khalfi,Florra Maillot,Paul Seigneres,Samy Sid Ahmedet al. Médecine/Sciences, 2018, 34 (6-7), pp.512-515. ⟨10.1051/medsci/20183406006⟩ Article dans une revue hal-02970124v1
Genetic Flexibility of the NKNK Motif in HIV-1 Integrases Allows Its Involvement in Multiple Functions During Infection Marine Kanja,Pierre Cappy,Guillermo Blanco-Rodriguez,Nicolas Levy,Sylvie Schmidtet al. Synthetic Biology eJournal, 2018, ⟨10.2139/ssrn.3208264⟩ Article dans une revue hal-03008742v1
Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells Cindy Buffone,Alicia Martinez-Lopez,Thomas Fricke,Silvana Opp,Marco Severgniniet al. Journal of Virology, 2018, 92 (19), pp.e00648-18. ⟨10.1128/JVI.00648-18⟩ Article dans une revue pasteur-03106145v1
SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV Daniel A. Donahue,Sonia Amraoui,Francesca Di Nunzio,Camille Kieffer,Françoise Porrotet al. Journal of Virology, 2016, 90 (8), pp.4199 - 4214. ⟨10.1128/JVI.03202-15⟩ Article dans une revue pasteur-01372386v1
Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal Bianca Schulte,Cindy Buffone,Silvana Opp,Francesca Di Nunzio,Daniel Augusto de Souza Aranha Vieiraet al. Journal of Virology, 2015, 89 (16), pp.8599 - 8610. ⟨10.1128/JVI.00753-15⟩ Article dans une revue pasteur-01536195v1
Chromatin organization at the nuclear pore favours HIV replication. Mickaël Lelek,Nicoletta Casartelli,Danilo Pellin,Ermanno Rizzi,Philippe Souqueet al. Nature Communications, 2015, 6, pp.6483. ⟨10.1038/ncomms7483⟩ Article dans une revue pasteur-01536149v1
Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses. Hao Wang,Ming-Chieh Shun,Xiang Li,Francesca Di Nunzio,Stephen Hareet al. Molecular Therapy - Methods and Clinical Development, 2014, 1 (2), ⟨10.1038/mtm.2013.2⟩ Article dans une revue hal-01536152v1
New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration. Francesca Di Nunzio Virus Research, 2013, 178 (2), pp.187-96. ⟨10.1016/j.virusres.2013.09.003⟩ Article dans une revue pasteur-01536158v1
Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication. Francesca Di Nunzio,Thomas Fricke,Annarita Miccio,Jose Carlos Valle-Casuso,Patricio Perezet al. Virology, 2013, 440 (1), pp.8-18. ⟨10.1016/j.virol.2013.02.008⟩ Article dans une revue pasteur-01536160v1
TOX4 and NOVA1 Proteins Are Partners of the LEDGF PWWP Domain and Affect HIV-1 Replication Mehdi Morchikh,Monica Naughtin,Francesca Di Nunzio,Johan Xavier,Pierre Charneauet al. PLoS ONE, 2013, 8, pp.81217 - 81217. ⟨10.1371/journal.pone.0081217.s005⟩ Article dans une revue pasteur-01416848v1
Superresolution imaging of HIV in infected cells with FlAsH-PALM. Mickaël Lelek,Francesca Di Nunzio,Ricardo Henriques,Pierre Charneau,Nathalie Arhelet al. Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (22), pp.8564-9. ⟨10.1073/pnas.1013267109⟩ Article dans une revue pasteur-01536166v1
TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core. Jose Carlos Valle-Casuso,Francesca Di Nunzio,Yang Yang,Natalia Reszka,Maritza Lienlafet al. Journal of Virology, 2012, 86 (10), pp.5931-6. ⟨10.1128/JVI.00451-12⟩ Article dans une revue hal-00762028v1
HIV-derived vectors for therapy and vaccination against HIV Francesca Di Nunzio,T. Félix,N.J. Arhel,S. Nisole,P. Charneauet al. Vaccine, 2012, 30 (15), pp.2499-2509. ⟨10.1016/j.vaccine.2012.01.089⟩ Article dans une revue istex hal-02142314v1
Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration. Francesca Di Nunzio,Anne Danckaert,Thomas Fricke,Patricio Perez,Juliette Fernandezet al. PLoS ONE, 2012, 7 (9), pp.e46037. ⟨10.1371/journal.pone.0046037⟩ Article dans une revue pasteur-01536163v1
Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha. Maritza Lienlaf,Fumiaki Hayashi,Francesca Di Nunzio,Naoya Tochio,Takanori Kigawaet al. Journal of Virology, 2011, 85 (17), pp.8725-37. ⟨10.1128/JVI.00497-11⟩ Article dans une revue pasteur-01536176v1
Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection Candela Iglesias,Mathieu Ringeard,Francesca Di Nunzio,Juliette Fernandez,Raphael Gaudinet al. Retrovirology, 2011, 8 (1), pp.92. ⟨10.1186/1742-4690-8-92⟩ Article dans une revue pasteur-00646599v1
Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase. Mohd J Dar,Blandine Monel,Lavanya Krishnan,Ming-Chieh Shun,Francesca Di Nunzioet al. Retrovirology, 2009, 6 (1), pp.94. ⟨10.1186/1742-4690-6-94⟩ Article dans une revue pasteur-01536178v1
Structural basis for functional tetramerization of lentiviral integrase. Stephen Hare,Francesca Di Nunzio,Alfred Labeja,Jimin Wang,Alan Engelmanet al. PLoS Pathogens, 2009, 5 (7), pp.e1000515. ⟨10.1371/journal.ppat.1000515⟩ Article dans une revue pasteur-01536181v1
Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity. Ming-Chieh Shun,Yaïr Botbol,Xiang Li,Francesca Di Nunzio,Janet E Daigleet al. Journal of Virology, 2008, 82 (23), pp.11555-67. ⟨10.1128/JVI.01561-08⟩ Article dans une revue pasteur-01536189v1
Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors. Francesca Di Nunzio,Giulietta Maruggi,Stefano Ferrari,Enzo Di Iorio,Valentina Polettiet al. Molecular Therapy, 2008, 16 (12), pp.1977-85. ⟨10.1038/mt.2008.204⟩ Article dans une revue hal-01536184v1
Transduction of Human Hematopoietic Stem Cells by Lentiviral Vectors Pseudotyped with the RD114-TR Chimeric Envelope Glycoprotein Francesca Di Nunzio,B. Piovani,Cosset François-Loïc,F. Mavilio,A. Stornaiuolo Human Gene Therapy, 2007, 18 (9), pp.811-820. ⟨10.1089/hum.2006.138⟩ Article dans une revue hal-03110979v1
Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells. Fulvio Mavilio,Graziella Pellegrini,Stefano Ferrari,Francesca Di Nunzio,Enzo Di Iorioet al. Nature Medicine, 2006, 12 (12), pp.1397-402. ⟨10.1038/nm1504⟩ Article dans une revue pasteur-01536191v1

Pré-publication, Document de travail (2)

A versatile reporter system to study cell-to-cell and cell-free bovine leukemia virus infection Florencia Rammauro,Martín Fló,Federico Carrión,Claudia Ortega,Francesca Di Nunzioet al. 2024 Pré-publication, Document de travail pasteur-05005109v1
Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages Elena Rensen,Florian Mueller,Viviana Scoca,Jyotsana Parmar,Philippe Souqueet al. 2020 Pré-publication, Document de travail pasteur-02559460v1

Chapitre d'ouvrage (3)

Characterization of Nuclear HIV-Induced Membraneless Organelles Through Fluorescence Microscopy Viviana Scoca,Francesca Di Nunzio Vinayaka R. Prasad; Ganjam V. Kalpana. HIV Protocols [4th edition], 2807, Springer, pp.113-125, 2024, Methods in Molecular Biology, 978-1-0716-3861-3. ⟨10.1007/978-1-0716-3862-0_8⟩ Chapitre d'ouvrage pasteur-04598269v1
Nuclear Pore Complexes, Genome Organization and HIV-1 Infection Francesca Di Nunzio Nuclear Pore Complexes in Genome Organization, Function and Maintenance, Springer International Publishing, pp.183-199, 2018, 978-3-319-71614-5. ⟨10.1007/978-3-319-71614-5_8⟩ Chapitre d'ouvrage hal-03110980v1
FlAsH-PALM: super-resolution pointillist imaging with FlAsH-tetracysteine labeling. Mickaël Lelek,Francesca Di Nunzio,Christophe Zimmer Andrei I. Ivanov. Exocytosis and Endocytosis, 1174, Springer New York, pp.183-93, 2014, Methods in Molecular Biology, 978-1-4939-0943-8. ⟨10.1007/978-1-4939-0944-5_12⟩ Chapitre d'ouvrage pasteur-01536156v1