Franck Picard

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Publications

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Minimax estimation of Functional Principal Components from noisy discretized functional data.

Ryad Belhakem , Franck F. Picard , Vincent Rivoirard , Angelina Roche

Scandinavian Journal of Statistics, 2025, 52 (1), pp.38-80. ⟨10.1111/sjos.12719⟩

Article dans une revue hal-03395522v2
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Mast cells act as pro-angiogenic and pro-tumorigenic players in pituitary gonadotroph tumors

Mirela-Diana Ilie , Álvaro Flores-Martínez , Marie Chanal , Maxime Lepetit , Benoit Samson et al.

Neuro-Oncology, 2025, ⟨10.1093/neuonc/noaf241⟩

Article dans une revue hal-05328726v1
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Differentiation is accompanied by a progressive loss in transcriptional memory

Camille Fourneaux , Laëtitia Racine , Catherine Koering , Sébastien Dussurgey , Elodie Vallin et al.

BMC Biology, 2024, 22 (1), pp.58. ⟨10.1186/s12915-024-01846-9⟩

Article dans une revue hal-04734188v1
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Kernel-Based Testing for Single-Cell Differential Analysis

Anthony Ozier-Lafontaine , Camille Fourneaux , Ghislain Durif , Polina Arsenteva , Céline Vallot et al.

Genome Biology, 2024, 114, ⟨10.1186/s13059-024-03255-1⟩

Article dans une revue hal-04214858v2
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In silico single-cell metabolism analysis unravels a new transition stage of CD8 T cells 4 days post-infection

Christophe Arpin , Franck Picard , Olivier Gandrillon

ImmunoInformatics, 2023, 14, pp.100038. ⟨10.1101/2023.09.22.558248⟩

Article dans une revue hal-04566377v1
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Dimeric G-quadruplex motifs-induced NFRs determine strong replication origins in vertebrates

Jérémy Poulet-Benedetti , Caroline Tonnerre-Doncarli , Anne-Laure Valton , Marc Laurent , Marie Gérard et al.

Nature Communications, 2023, 14 (1), pp.4843. ⟨10.1038/s41467-023-40441-4⟩

Article dans une revue hal-04184349v1
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scAN1.0: A reproducible and standardized pipeline for processing 10X single cell RNAseq data

Maxime Lepetit , Mirela Diana Ilie , Marie Chanal , Gérald Raverot , Philippe Bertolino et al.

In Silico Biology, 2023, 15, pp.11 - 21. ⟨10.3233/isb-220252⟩

Article dans une revue hal-04305326v1
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A derived ZW chromosome system in Amborella trichopoda, representing the sister lineage to all other extant flowering plants

Jos Käfer , Adam Bewick , Amélie Andres‐robin , Garance Lapetoule , Alex Harkess et al.

New Phytologist, 2022, 233, pp.1636-1642. ⟨10.1111/nph.17662⟩

Article dans une revue hal-03370272v1
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Evidence for close molecular proximity between reverting and undifferentiated cells

Souad Zreika , Camille Fourneaux , Elodie Vallin , Laurent Modolo , Remi Seraphin et al.

BMC Biology, 2022, 20 (1), pp.155. ⟨10.1186/s12915-022-01363-7⟩

Article dans une revue hal-04134084v1
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Uniform Deconvolution for Poisson Point Processes

Anna Bonnet , Claire Lacour , Franck Picard , Vincent Rivoirard

Journal of Machine Learning Research, 2022, 23 (194), pp.1--36

Article dans une revue hal-02964117v2
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Detecting sex-linked genes using genotyped individuals sampled in natural populations

Jos Käfer , Nicolas Lartillot , Gabriel a B Marais , Franck Picard

Genetics, 2021, 218 (2), ⟨10.1093/genetics/iyab053⟩

Article dans une revue hal-03250679v1
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Divergent clonal differentiation trajectories establish CD8+ memory T cell heterogeneity during acute viral infections in humans

Jeff Mold , Laurent Modolo , Joanna Hård , Margherita Zamboni , Anton J.M. Larsson et al.

Cell Reports, 2021, 35 (8), pp.109174. ⟨10.1016/j.celrep.2021.109174⟩

Article dans une revue hal-03345357v1
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The wild grape genome sequence provides insights into the transition from dioecy to hermaphroditism during grape domestication

Hélène E Badouin , Amandine Velt , François Gindraud , Timothée Flutre , Vincent Dumas et al.

Genome Biology, 2020, 21 (1), pp.223. ⟨10.1186/s13059-020-02131-y⟩

Article dans une revue hal-02946414v1
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Clustering of strong replicators associated with active promoters is sufficient to establish an early-replicating domain

Caroline Brossas , Anne-Laure Valton , Sergey V Venev , Sabarinadh Chilaka , Antonin Counillon et al.

EMBO Journal, 2020, ⟨10.15252/embj.201899520⟩

Article dans une revue hal-03023038v1
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Evolution of replication origins in vertebrate genomes: rapid turnover despite selective constraints

Florian Massip , Marc Laurent , Caroline Brossas , José miguel Fernández-Justel , Maria Gomez et al.

Nucleic Acids Research, 2019, 47 (10), pp.5114-5125. ⟨10.1093/nar/gkz182⟩

Article dans une revue hal-02349718v1
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Probabilistic Count Matrix Factorization for Single Cell Expression Data Analysis

Ghislain Durif , Laurent Modolo , Jeff E Mold , Sophie Lambert-Lacroix , Franck Picard

Bioinformatics, 2019, 35, 20, pp.4011-4019. ⟨10.1093/bioinformatics/btz177⟩

Article dans une revue hal-01649275v3
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Minimax wavelet estimation for multisample heteroscedastic nonparametric regression

Madison Giacofci , Sophie Lambert-Lacroix , Franck Picard

Journal of Nonparametric Statistics, 2018, 30 (1), pp.238-261. ⟨10.1080/10485252.2017.1406091⟩

Article dans une revue hal-02270811v1
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High Dimensional Classification with combined Adaptive Sparse PLS and Logistic Regression

Ghislain Durif , Laurent Modolo , Jakob Michaelsson , Jeff E. Mold , Sophie Lambert-Lacroix et al.

Bioinformatics, 2018, 34 (3), pp.485-493. ⟨10.1093/bioinformatics/btx571⟩

Article dans une revue hal-01587360v1
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Continuous testing for Poisson process intensities: a new perspective on scanning statistics

Franck Picard , Patricia Reynaud-Bouret , Etienne Roquain

Biometrika, 2018, ⟨10.1093/biomet/asy044⟩

Article dans une revue hal-02350783v1

Genomic imprinting mediates dosage compensation in a young plant XY system

Aline Muyle , Niklaus Zemp , Cécile Fruchard , Radim Cegan , Jan Vrána et al.

Nature Plants, 2018, 4 (9), pp.677-680. ⟨10.1038/s41477-018-0221-y⟩

Article dans une revue hal-02347985v1
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Adaptive Lasso and group-Lasso for functional Poisson regression

Stéphane Ivanoff , Franck Picard , Vincent Rivoirard

Journal of Machine Learning Research, 2016, 17 (55), pp.1--46

Article dans une revue hal-01097914v2
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SNP calling from RNA-seq data without a reference genome: identification, quantification, differential analysis and impact on the protein sequence

Hélène Lopez-Maestre , Lilia Brinza , Camille Marchet , Janice Kielbassa , Sylvère Bastien et al.

Nucleic Acids Research, 2016, ⟨10.1093/nar/gkw655⟩

Article dans une revue hal-01352586v1

Modeling overdispersion heterogeneity in differential expression analysis using mixtures

E. Bonafede , Franck Picard , S. Robin , C. Viroli

Biometrics, 2016, 72 (3), pp.804-814. ⟨10.1111/biom.12458⟩

Article dans une revue istex hal-02016384v1
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On the robustness of the generalized fused lasso to prior specifications

Vivian Viallon , Sophie Lambert-Lacroix , Holger Höfling , Franck Picard

Statistics and Computing, 2016, 26 (1), pp.285-301. ⟨10.1007/s11222-014-9497-6⟩

Article dans une revue hal-01067903v2
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SEX-DETector: a probabilistic approach to study sex chromosomes in non-model organisms

A. Muyle , Jos Käfer , N. Zemp , S. Mousset , Franck Picard et al.

Genome Biology and Evolution, 2016, 8, pp.2530-2543. ⟨10.1093/gbe/evw172⟩

Article dans une revue hal-02053627v1
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The spatiotemporal program of DNA replication is associated with specific combinations of chromatin marks in human cells.

Franck Picard , Jean-Charles Cadoret , Benjamin Audit , Alain Arneodo , Adriana A. Alberti et al.

PLoS Genetics, 2014, 10 (5), pp.e1004282. ⟨10.1371/journal.pgen.1004282⟩

Article dans une revue hal-00995097v1
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A new genome-wide method to track horizontally transferred sequences: application to Drosophila

L. Modolo , Franck Picard , E. Lerat

Genome Biology and Evolution, 2014, 6 (2), pp.416-32. ⟨10.1093/gbe/evu026⟩

Article dans une revue hal-02045117v1

Fast and Parallel Algorithm for Population-Based Segmentation of Copy-Number Profiles

Guillem Rigaill , Vincent Miele , Franck Picard

Lecture Notes in Computer Science, 2014, 8452, pp.248-258

Article dans une revue hal-02045097v1
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Spatially constrained clustering of ecological networks

Vincent Miele , Franck Picard , S. Dray

Methods in Ecology and Evolution, 2014, 5 (8), pp.771-779. ⟨10.1111/2041-210X.12208⟩

Article dans une revue hal-02045124v1

HOMER : a homogenization software - methods and applications

Olivier Mestre , Peter Domonkos , Franck Picard , Ingeborg Auer , Stephane Robin et al.

IDOJARAS, 2013, 117 (1), pp.47 - 67

Article dans une revue hal-01190665v1

Wavelet-based clustering for mixed-effects functional models in high dimension

Madison Giacofci , Sophie Lambert-Lacroix , Guillemette Marot , Franck Picard

Biometrics, 2013, 69 (1), pp.31-40. ⟨10.1111/j.1541-0420.2012.01828.x⟩

Article dans une revue istex hal-00782458v1

High-quality sequence clustering guided by network topology and multiple alignment likelihood.

Vincent Miele , Simon Penel , Vincent Daubin , Franck Picard , Daniel Kahn et al.

Bioinformatics, 2012, 28 (8), pp.1078-85. ⟨10.1093/bioinformatics/bts098⟩

Article dans une revue hal-00965711v1

Joint segmentation of multivariate Gaussian processes using mixed linear models

Franck F. Picard , E. Lebarbier , E. E. Budinska , Stephane S. Robin

Computational Statistics and Data Analysis, 2011, 55 (2), pp.1160 - 1170. ⟨10.1016/j.csda.2010.09.015⟩

Article dans une revue istex hal-01001452v1

Bioinformatics developments for NGS data analysis at PRABI

F. Picard , Guy Perrière

EMBNet.journal, 2011, 17, pp.12

Article dans une revue hal-02297662v1

Statistiques et Génome

Franck Picard , S. Schbath , E. Lebarbier , Pierre Neuvial , J. Chiquet

Gazette des Mathématiciens, 2011, 130, pp.1-32

Article dans une revue hal-00698143v1
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The auxin signalling network translates dynamic input into robust patterning at the shoot apex

Teva Vernoux , Géraldine Brunoud , Etienne Farcot , Valérie Morin , Hilde van Den Daele et al.

Molecular Systems Biology, 2011, 7 (508), ⟨10.1038/msb.2011.39⟩

Article dans une revue hal-00828880v1
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Joint segmentation, calling, and normalization of multiple CGH profiles

Franck Picard , Mark Hoebeke , Guillem Rigaill , Baba Thiam , Stephane Robin

Biostatistics, 2011, 12 (3), pp.413-428. ⟨10.1093/biostatistics/kxq076⟩

Article dans une revue hal-01019859v1

Strategies for online inference of model-based clustering in large and growing networks

H. Zanghi , Franck Picard , V. Miele , C. Ambroise

Annals of Applied Statistics, 2010, 4 (2), pp.687-714. ⟨10.1214/10-AOAS359⟩

Article dans une revue hal-00539318v1

Preprocessing and downstream analysis of microarray DNA copy number profiles

M.A. van de Wiel , Franck Picard , W.N. van Wieringen , B. Ylstra

Briefings in Bioinformatics, 2010, 12 (1), pp.10-21. ⟨10.1093/bib/bbq004⟩

Article dans une revue hal-00539440v1

Deciphering the connectivity structure of biological networks using MixNet

Franck Picard , V. Miele , L. Cottret , J.J. Daudin , S. Robin

BMC Bioinformatics, 2009, in press, pp.1-1

Article dans une revue hal-00391483v1
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Deciphering the connectivity structure of biological networks using MixNet

Franck Picard , Vincent Miele , Jean-Jacques J.-J. Daudin , Ludovic Cottret , Stephane S. Robin

BMC Bioinformatics, 2009, 10, pp.1-11. ⟨10.1186/1471-2105-10-S6-S17⟩

Article dans une revue hal-02658961v1

Deciphering the connectivity structure of biological networks using MixNet

Franck Picard , V. Miele , J.J. Daudin , L. Cottret , S. Robin

BMC Bioinformatics, 2009, 10, pp.1-11

Article dans une revue hal-00428390v1

Assessing the exceptionality of network motifs

Franck Picard , Jean-Jacques Daudin , Michel Koskas , Sophie Schbath , Stephane Robin

Journal of Computational Biology, 2008, 15 (1), pp.1-20. ⟨10.1089/cmb.2007.0137⟩

Article dans une revue hal-01197499v1

A mixture model for random graphs

J.-J. Daudin , Franck Picard , S. Robin

Statistics and Computing, 2008, 18, pp.173-183

Article dans une revue hal-00428180v1

A mixture model for random graphs

Jean-Jacques Daudin , Franck Picard , Stephane Robin

Statistics and Computing, 2008, 18 (2), pp.173-183. ⟨10.1007/s11222-007-9046-7⟩

Article dans une revue hal-01197587v1

Assessing the exceptionality of network motifs

Franck Picard , J.-J. Daudin , M. Koskas , S. Schbath , S. Robin

Journal of Computational Biology, 2008, 15, pp.1-20

Article dans une revue hal-00428157v1

A segmentation/clustering model for the analysis of array CGH data

Franck Picard , S. Robin , E. Lebarbier , J.-J. Daudin

Biometrics, 2007, 63, pp.758-766

Article dans une revue hal-00434826v1

Computing power in case-control association studies through the use of quadratic approximations: application to meat-statistics

M. Guedj , E. Della-Chiesa , Franck Picard , Gregory Nuel

Annals of Human Genetics, 2007, --, pp.57-62

Article dans une revue hal-00434865v1
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A segmentation/clustering model for the analysis of array CGH data

Franck Picard , Stephane Robin , Jean-Jacques Daudin

Biometrics, 2007, 63 (3), pp.758-766. ⟨10.1111/j.1541-0420.2006.00729.x⟩

Article dans une revue istex hal-01197574v1

Melanocortin-4 receptor mutations in a large cohort of severely obese adults: prevalence functional classification genotype-phenotype relationship and lack of association with binge eating

C. Lubrano-Berthelier , B. Dubern , J.-M. Lacorte , Franck Picard , A. Shapiro et al.

Journal of Clinical Endocrinology and Metabolism, 2006, 91, pp.1811-1818

Article dans une revue hal-00427994v1

Uncovering structure in biological networks

J.J. Daudin , Vincent Lacroix , M. Mariadassou , V. Miele , Franck Picard et al.

incollection, 2006, --, pp.471-483

Article dans une revue hal-00427936v1
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A statistical approach for array CGH data analysis

Franck Picard , Stephane Robin , Marc Lavielle , Christian Vaisse , Jean-Jacques Daudin

BMC Bioinformatics, 2005, 6, ⟨10.1186/1471-2105-6-27⟩

Article dans une revue hal-01222433v1

Obesity-associated mutations in the melanocortin-4 receptor provide novel insights into its function

C. Govaerts , S. Srinivasan , A. Shapiro , S. Zhang , Franck Picard et al.

Peptides, 2005, 26, pp.1909-1919

Article dans une revue hal-00427759v1

A statistical approach for array CGH data analysis

Franck Picard , S. Robin , M. Lavielle , C. Vaisse , J.-J. Daudin

BMC Bioinformatics, 2005, 6, pp.1-14

Article dans une revue hal-00427846v1

Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans

S. Srinivasan , C. Lubrano-Berthelier , C. Govaerts , Franck Picard , P. Santiago et al.

Journal of Clinical Investigation, 2004, 114, pp.1158-1164

Article dans une revue hal-00427559v1

Molecular genetics of human obesity-associated MC4R mutations

C. Lubrano-Berthelier , M. Cavazos , B. Dubern , A. Shapiro , C. Le Stunff et al.

Annals of the New York Academy of Sciences, 2003, 994, pp.49-57

Article dans une revue hal-00427443v1

kAOV : kernel hypothesis testing on general designs

Polina Arsenteva , Anthony Ozier-Lafontaine , Franck Picard , Bertrand Michel , Ghislain Durif Logiciel hal-04894520v1

pppca: Principal Component Analysis for replicated point process data.

Ghislain Durif , Franck Picard , Vincent Rivoirard , Angelina Roche , Victor Panaretos Logiciel hal-04894590v1

ktest : two-sample kernel testing

Anthony Ozier-Lafontaine , Polina Arsenteva , Ghislain Durif , Franck Picard Logiciel hal-04547380v1

scan10 : Nextflow pipeline for pre-processing and preliminary analysis of single cell RNA-seq data

Maxime Lepetit , Laurent Modolo , Franck Picard , Philippe Bertolino Logiciel hal-04911084v1
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A Probabilistic Graph Coupling View of Dimension Reduction

Hugues van Assel , Thibault Espinasse , Julien Chiquet , Franck Picard

Advances in Neural Information Processing Systems, Nov 2022, Nouvelle-Orleans, United States. pp.10696-10708

Communication dans un congrès hal-03548776v3
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Probabilistic Count Matrix Factorization for Single Cell Expression Data Analysis

Ghislain Durif , Laurent Modolo , Jeff E. Mold , Sophie Lambert-Lacroix , Franck Picard

RECOMB 2018 - 22nd Annual International Conference on Research in Computational Molecular Biology, Ecole Polytechnique, Apr 2018, Paris, France. pp.254-255

Communication dans un congrès hal-01962030v1

Fast and parallel algorithm for population-based segmentation of copy-number profiles

Guillem Rigaill , Vincent Miele , Franck Picard

10. International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB), Jun 2013, Nice, France. 275 p., ⟨10.1007/978-3-319-09042-9_18⟩

Communication dans un congrès hal-02742012v1

Wavelet-based clustering for mixed-effects functional models

Madison Giacofci , Sophie Lambert-Lacroix , Franck Picard

43eme Journées de Statistiques, May 2011, Gammarth, Tunisie

Communication dans un congrès hal-00987676v1
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Modeling the structure and dynamics of the auxin signaling network in the shoot apical meristem

Etienne Farcot , Yann Guédon , Géraldine Brunoud , Jonathan Legrand , Hilde van Den Daele et al.

6th International Workshop on Functional-Structural Plant Models, 2010, Davis, Canada. pp.146-148

Communication dans un congrès hal-00831786v1
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Modèle linéaire mixte avec segmentation : application à la détection de changements dans les dates de vendanges

Franck Picard , Eva Budinska , Stephane Robin

42. Journées de Statistique, May 2010, Marseille, France

Communication dans un congrès hal-01197573v1
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Modèle linéaire mixte avec segmentation : application à la détection de changements dans les dates de vendanges

Emilie Lebarbier , Franck Picard , Eva Budinska , Stéphane Robin

42èmes Journées de Statistique, 2010, Marseille, France, France

Communication dans un congrès inria-00494861v1
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Statistical assessment of chromosomal aberrations at the cohort level: the CGHSeg package

Franck Picard , Baba Thiam , Stephane Robin

The 5. R useR Conference, Jul 2009, Rennes, France. 18 p

Communication dans un congrès hal-01197546v1
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Joint segmentation of multivariate Gaussian processes using mixed linear models

Franck Picard , Eva Budinska , Stephane S. Robin

12. International Conference on Applied Stochastic Models and Data Analysis, Jun 2007, Chania, Greece

Communication dans un congrès hal-02751255v1

Assessing the exceptionality of network motifs

Franck Picard , Jean-Jacques Daudin , Michel Koskas , Sophie Schbath , Stephane Robin

JOBIM Journées Ouvertes Biologie Informatique Mathématiques, Jul 2007, Marseille, France

Communication dans un congrès hal-01197515v1