Franck Picard

Publications

Pré-publication, Document de travail (8)

Non-asymptotic two-sample kernel testing with the spectrally truncated normalized MMD Perrine Lacroix,Bertrand Michel,Franck Picard,Vincent Rivoirard 2026 Pré-publication, Document de travail hal-05585435v1
PCA for Point Processes Franck Picard,Vincent Rivoirard,Angelina Roche,Victor Panaretos 2025 Pré-publication, Document de travail hal-04740986v2
Extending Kernel Testing To General Designs Anthony Ozier-Lafontaine,Franck Picard,Bertrand Michel 2024 Pré-publication, Document de travail hal-04747959v1
Dimeric G-quadruplex motifs determine a large fraction of strong replication origins in vertebrates Jérémy Poulet-Benedetti,Caroline Tonnerre-Doncarli,Anne-Laure Valton,Marc Laurent,Marie Gérardet al. 2023 Pré-publication, Document de travail (preprint/prepublication) hal-03932439v1
CPCN - BILAN DE MANDATURE 2016 – 2021 Olivier Coutard,Pierre-Olivier Amblard,Claude Amra,Brigitte Bacroix,Pascal Baroneet al. 2021 Pré-publication, Document de travail hal-03413289v2
Detecting sex-linked genes using genotyped individuals sampled in natural populations Jos Käfer,Nicolas Lartillot,Gabriel Marais,Franck Picard 2020 Pré-publication, Document de travail hal-02490340v1
Genomic imprinting mediates dosage compensation in a young plant XY system. Aline Muyle,Niklaus Zemp,Cécile Fruchard,Radim Cegan,Jan Vránaet al. 2018 Pré-publication, Document de travail hal-01851376v1
Adaptive Generalized Fused-Lasso: Asymptotic Properties and Applications Vivian Viallon,Sophie Lambert-Lacroix,Holger Höfling,Franck Picard 2013 Pré-publication, Document de travail hal-00813281v1

Article dans une revue (55)

Mast cells act as pro-angiogenic and pro-tumorigenic players in pituitary gonadotroph tumors Mirela-Diana Ilie,Álvaro Flores-Martínez,Marie Chanal,Maxime Lepetit,Benoit Samsonet al. Neuro-Oncology, 2025, ⟨10.1093/neuonc/noaf241⟩ Article dans une revue hal-05328726v1
Minimax estimation of Functional Principal Components from noisy discretized functional data. Ryad Belhakem,Franck F. Picard,Vincent Rivoirard,Angelina Roche Scandinavian Journal of Statistics, 2025, 52 (1), pp.38-80. ⟨10.1111/sjos.12719⟩ Article dans une revue hal-03395522v2
Kernel-Based Testing for Single-Cell Differential Analysis Anthony Ozier-Lafontaine,Camille Fourneaux,Ghislain Durif,Polina Arsenteva,Céline Vallotet al. Genome Biology, 2024, 114, ⟨10.1186/s13059-024-03255-1⟩ Article dans une revue hal-04214858v2
Differentiation is accompanied by a progressive loss in transcriptional memory Camille Fourneaux,Laëtitia Racine,Catherine Koering,Sébastien Dussurgey,Elodie Vallinet al. BMC Biology, 2024, 22 (1), pp.58. ⟨10.1186/s12915-024-01846-9⟩ Article dans une revue hal-04734188v1
In silico single-cell metabolism analysis unravels a new transition stage of CD8 T cells 4 days post-infection Christophe Arpin,Franck Picard,Olivier Gandrillon ImmunoInformatics, 2023, 14, pp.100038. ⟨10.1101/2023.09.22.558248⟩ Article dans une revue hal-04566377v1
scAN1.0: A reproducible and standardized pipeline for processing 10X single cell RNAseq data Maxime Lepetit,Mirela Diana Ilie,Marie Chanal,Gérald Raverot,Philippe Bertolinoet al. In Silico Biology, 2023, 15, pp.11 - 21. ⟨10.3233/isb-220252⟩ Article dans une revue hal-04305326v1
Dimeric G-quadruplex motifs-induced NFRs determine strong replication origins in vertebrates Jérémy Poulet-Benedetti,Caroline Tonnerre-Doncarli,Anne-Laure Valton,Marc Laurent,Marie Gérardet al. Nature Communications, 2023, 14 (1), pp.4843. ⟨10.1038/s41467-023-40441-4⟩ Article dans une revue hal-04184349v1
A derived ZW chromosome system in Amborella trichopoda, representing the sister lineage to all other extant flowering plants Jos Käfer,Adam Bewick,Amélie Andres‐robin,Garance Lapetoule,Alex Harkesset al. New Phytologist, 2022, 233, pp.1636-1642. ⟨10.1111/nph.17662⟩ Article dans une revue hal-03370272v1
Evidence for close molecular proximity between reverting and undifferentiated cells Souad Zreika,Camille Fourneaux,Elodie Vallin,Laurent Modolo,Remi Seraphinet al. BMC Biology, 2022, 20 (1), pp.155. ⟨10.1186/s12915-022-01363-7⟩ Article dans une revue hal-04134084v1
Uniform Deconvolution for Poisson Point Processes Anna Bonnet,Claire Lacour,Franck Picard,Vincent Rivoirard Journal of Machine Learning Research, 2022, 23 (194), pp.1--36 Article dans une revue hal-02964117v2
Detecting sex-linked genes using genotyped individuals sampled in natural populations Jos Käfer,Nicolas Lartillot,Gabriel a B Marais,Franck Picard Genetics, 2021, 218 (2), ⟨10.1093/genetics/iyab053⟩ Article dans une revue hal-03250679v1
Divergent clonal differentiation trajectories establish CD8+ memory T cell heterogeneity during acute viral infections in humans Jeff Mold,Laurent Modolo,Joanna Hård,Margherita Zamboni,Anton J.M. Larssonet al. Cell Reports, 2021, 35 (8), pp.109174. ⟨10.1016/j.celrep.2021.109174⟩ Article dans une revue hal-03345357v1
Clustering of strong replicators associated with active promoters is sufficient to establish an early-replicating domain Caroline Brossas,Anne-Laure Valton,Sergey V Venev,Sabarinadh Chilaka,Antonin Counillonet al. EMBO Journal, 2020, ⟨10.15252/embj.201899520⟩ Article dans une revue hal-03023038v1
The wild grape genome sequence provides insights into the transition from dioecy to hermaphroditism during grape domestication Hélène E Badouin,Amandine Velt,François Gindraud,Timothée Flutre,Vincent Dumaset al. Genome Biology, 2020, 21 (1), pp.223. ⟨10.1186/s13059-020-02131-y⟩ Article dans une revue hal-02946414v1
Probabilistic Count Matrix Factorization for Single Cell Expression Data Analysis Ghislain Durif,Laurent Modolo,Jeff E Mold,Sophie Lambert-Lacroix,Franck Picard Bioinformatics, 2019, 35, 20, pp.4011-4019. ⟨10.1093/bioinformatics/btz177⟩ Article dans une revue hal-01649275v3
Evolution of replication origins in vertebrate genomes: rapid turnover despite selective constraints Florian Massip,Marc Laurent,Caroline Brossas,José miguel Fernández-Justel,Maria Gomezet al. Nucleic Acids Research, 2019, 47 (10), pp.5114-5125. ⟨10.1093/nar/gkz182⟩ Article dans une revue hal-02349718v1
High Dimensional Classification with combined Adaptive Sparse PLS and Logistic Regression Ghislain Durif,Laurent Modolo,Jakob Michaelsson,Jeff E. Mold,Sophie Lambert-Lacroixet al. Bioinformatics, 2018, 34 (3), pp.485-493. ⟨10.1093/bioinformatics/btx571⟩ Article dans une revue hal-01587360v1
Continuous testing for Poisson process intensities: a new perspective on scanning statistics Franck Picard,Patricia Reynaud-Bouret,Etienne Roquain Biometrika, 2018, ⟨10.1093/biomet/asy044⟩ Article dans une revue hal-02350783v1
Genomic imprinting mediates dosage compensation in a young plant XY system Aline Muyle,Niklaus Zemp,Cécile Fruchard,Radim Cegan,Jan Vránaet al. Nature Plants, 2018, 4 (9), pp.677-680. ⟨10.1038/s41477-018-0221-y⟩ Article dans une revue hal-02347985v1
Minimax wavelet estimation for multisample heteroscedastic nonparametric regression Madison Giacofci,Sophie Lambert-Lacroix,Franck Picard Journal of Nonparametric Statistics, 2018, 30 (1), pp.238-261. ⟨10.1080/10485252.2017.1406091⟩ Article dans une revue hal-02270811v1
On the robustness of the generalized fused lasso to prior specifications Vivian Viallon,Sophie Lambert-Lacroix,Holger Höfling,Franck Picard Statistics and Computing, 2016, 26 (1), pp.285-301. ⟨10.1007/s11222-014-9497-6⟩ Article dans une revue hal-01067903v2
SEX-DETector: a probabilistic approach to study sex chromosomes in non-model organisms A. Muyle,Jos Käfer,N. Zemp,S. Mousset,Franck Picardet al. Genome Biology and Evolution, 2016, 8, pp.2530-2543. ⟨10.1093/gbe/evw172⟩ Article dans une revue hal-02053627v1
Adaptive Lasso and group-Lasso for functional Poisson regression Stéphane Ivanoff,Franck Picard,Vincent Rivoirard Journal of Machine Learning Research, 2016, 17 (55), pp.1--46 Article dans une revue hal-01097914v2
SNP calling from RNA-seq data without a reference genome: identification, quantification, differential analysis and impact on the protein sequence Hélène Lopez-Maestre,Lilia Brinza,Camille Marchet,Janice Kielbassa,Sylvère Bastienet al. Nucleic Acids Research, 2016, ⟨10.1093/nar/gkw655⟩ Article dans une revue hal-01352586v1
Modeling overdispersion heterogeneity in differential expression analysis using mixtures E. Bonafede,Franck Picard,S. Robin,C. Viroli Biometrics, 2016, 72 (3), pp.804-814. ⟨10.1111/biom.12458⟩ Article dans une revue istex hal-02016384v1
A new genome-wide method to track horizontally transferred sequences: application to Drosophila L. Modolo,Franck Picard,E. Lerat Genome Biology and Evolution, 2014, 6 (2), pp.416-32. ⟨10.1093/gbe/evu026⟩ Article dans une revue hal-02045117v1
The spatiotemporal program of DNA replication is associated with specific combinations of chromatin marks in human cells. Franck Picard,Jean-Charles Cadoret,Benjamin Audit,Alain Arneodo,Adriana A. Albertiet al. PLoS Genetics, 2014, 10 (5), pp.e1004282. ⟨10.1371/journal.pgen.1004282⟩ Article dans une revue hal-00995097v1
Fast and Parallel Algorithm for Population-Based Segmentation of Copy-Number Profiles Guillem Rigaill,Vincent Miele,Franck Picard Lecture Notes in Computer Science, 2014, 8452, pp.248-258 Article dans une revue hal-02045097v1
Spatially constrained clustering of ecological networks Vincent Miele,Franck Picard,S. Dray Methods in Ecology and Evolution, 2014, 5 (8), pp.771-779. ⟨10.1111/2041-210X.12208⟩ Article dans une revue hal-02045124v1
HOMER : a homogenization software - methods and applications Olivier Mestre,Peter Domonkos,Franck Picard,Ingeborg Auer,Stephane Robinet al. IDOJARAS, 2013, 117 (1), pp.47 - 67 Article dans une revue hal-01190665v1
Wavelet-based clustering for mixed-effects functional models in high dimension Madison Giacofci,Sophie Lambert-Lacroix,Guillemette Marot,Franck Picard Biometrics, 2013, 69 (1), pp.31-40. ⟨10.1111/j.1541-0420.2012.01828.x⟩ Article dans une revue istex hal-00782458v1
High-quality sequence clustering guided by network topology and multiple alignment likelihood. Vincent Miele,Simon Penel,Vincent Daubin,Franck Picard,Daniel Kahnet al. Bioinformatics, 2012, 28 (8), pp.1078-85. ⟨10.1093/bioinformatics/bts098⟩ Article dans une revue hal-00965711v1
Statistiques et Génome Franck Picard,S. Schbath,E. Lebarbier,Pierre Neuvial,J. Chiquet Gazette des Mathématiciens, 2011, 130, pp.1-32 Article dans une revue hal-00698143v1
Bioinformatics developments for NGS data analysis at PRABI F. Picard,Guy Perrière EMBNet.journal, 2011, 17, pp.12 Article dans une revue hal-02297662v1
The auxin signalling network translates dynamic input into robust patterning at the shoot apex Teva Vernoux,Géraldine Brunoud,Etienne Farcot,Valérie Morin,Hilde van Den Daeleet al. Molecular Systems Biology, 2011, 7 (508), ⟨10.1038/msb.2011.39⟩ Article dans une revue hal-00828880v1
Joint segmentation, calling, and normalization of multiple CGH profiles Franck Picard,Mark Hoebeke,Guillem Rigaill,Baba Thiam,Stephane Robin Biostatistics, 2011, 12 (3), pp.413-428. ⟨10.1093/biostatistics/kxq076⟩ Article dans une revue hal-01019859v1
Joint segmentation of multivariate Gaussian processes using mixed linear models Franck F. Picard,E. Lebarbier,E. E. Budinska,Stephane S. Robin Computational Statistics and Data Analysis, 2011, 55 (2), pp.1160 - 1170. ⟨10.1016/j.csda.2010.09.015⟩ Article dans une revue istex hal-01001452v1
Preprocessing and downstream analysis of microarray DNA copy number profiles M.A. van de Wiel,Franck Picard,W.N. van Wieringen,B. Ylstra Briefings in Bioinformatics, 2010, 12 (1), pp.10-21. ⟨10.1093/bib/bbq004⟩ Article dans une revue hal-00539440v1
Strategies for online inference of model-based clustering in large and growing networks H. Zanghi,Franck Picard,V. Miele,C. Ambroise Annals of Applied Statistics, 2010, 4 (2), pp.687-714. ⟨10.1214/10-AOAS359⟩ Article dans une revue hal-00539318v1
Deciphering the connectivity structure of biological networks using MixNet Franck Picard,V. Miele,L. Cottret,J.J. Daudin,S. Robin BMC Bioinformatics, 2009, in press, pp.1-1 Article dans une revue hal-00391483v1
Deciphering the connectivity structure of biological networks using MixNet Franck Picard,Vincent Miele,Jean-Jacques J.-J. Daudin,Ludovic Cottret,Stephane S. Robin BMC Bioinformatics, 2009, 10, pp.1-11. ⟨10.1186/1471-2105-10-S6-S17⟩ Article dans une revue hal-02658961v1
Deciphering the connectivity structure of biological networks using MixNet Franck Picard,V. Miele,J.J. Daudin,L. Cottret,S. Robin BMC Bioinformatics, 2009, 10, pp.1-11 Article dans une revue hal-00428390v1
Assessing the exceptionality of network motifs Franck Picard,Jean-Jacques Daudin,Michel Koskas,Sophie Schbath,Stephane Robin Journal of Computational Biology, 2008, 15 (1), pp.1-20. ⟨10.1089/cmb.2007.0137⟩ Article dans une revue hal-01197499v1
A mixture model for random graphs Jean-Jacques Daudin,Franck Picard,Stephane Robin Statistics and Computing, 2008, 18 (2), pp.173-183. ⟨10.1007/s11222-007-9046-7⟩ Article dans une revue hal-01197587v1
Assessing the exceptionality of network motifs Franck Picard,J.-J. Daudin,M. Koskas,S. Schbath,S. Robin Journal of Computational Biology, 2008, 15, pp.1-20 Article dans une revue hal-00428157v1
Computing power in case-control association studies through the use of quadratic approximations: application to meat-statistics M. Guedj,E. Della-Chiesa,Franck Picard,Gregory Nuel Annals of Human Genetics, 2007, --, pp.57-62 Article dans une revue hal-00434865v1
A segmentation/clustering model for the analysis of array CGH data Franck Picard,Stephane Robin,Jean-Jacques Daudin Biometrics, 2007, 63 (3), pp.758-766. ⟨10.1111/j.1541-0420.2006.00729.x⟩ Article dans une revue istex hal-01197574v1
A segmentation/clustering model for the analysis of array CGH data Franck Picard,S. Robin,E. Lebarbier,J.-J. Daudin Biometrics, 2007, 63, pp.758-766 Article dans une revue hal-00434826v1
Melanocortin-4 receptor mutations in a large cohort of severely obese adults: prevalence functional classification genotype-phenotype relationship and lack of association with binge eating C. Lubrano-Berthelier,B. Dubern,J.-M. Lacorte,Franck Picard,A. Shapiroet al. Journal of Clinical Endocrinology and Metabolism, 2006, 91, pp.1811-1818 Article dans une revue hal-00427994v1
Uncovering structure in biological networks J.J. Daudin,Vincent Lacroix,M. Mariadassou,V. Miele,Franck Picardet al. incollection, 2006, --, pp.471-483 Article dans une revue hal-00427936v1
Obesity-associated mutations in the melanocortin-4 receptor provide novel insights into its function C. Govaerts,S. Srinivasan,A. Shapiro,S. Zhang,Franck Picardet al. Peptides, 2005, 26, pp.1909-1919 Article dans une revue hal-00427759v1
A statistical approach for array CGH data analysis Franck Picard,S. Robin,M. Lavielle,C. Vaisse,J.-J. Daudin BMC Bioinformatics, 2005, 6, pp.1-14 Article dans une revue hal-00427846v1
A statistical approach for array CGH data analysis Franck Picard,Stephane Robin,Marc Lavielle,Christian Vaisse,Jean-Jacques Daudin BMC Bioinformatics, 2005, 6, ⟨10.1186/1471-2105-6-27⟩ Article dans une revue hal-01222433v1
Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans S. Srinivasan,C. Lubrano-Berthelier,C. Govaerts,Franck Picard,P. Santiagoet al. Journal of Clinical Investigation, 2004, 114, pp.1158-1164 Article dans une revue hal-00427559v1
Molecular genetics of human obesity-associated MC4R mutations C. Lubrano-Berthelier,M. Cavazos,B. Dubern,A. Shapiro,C. Le Stunffet al. Annals of the New York Academy of Sciences, 2003, 994, pp.49-57 Article dans une revue hal-00427443v1

Logiciel (4)

kAOV : kernel hypothesis testing on general designs Polina Arsenteva,Anthony Ozier-Lafontaine,Franck Picard,Bertrand Michel,Ghislain Durif 2025, ⟨swh:1:dir:ee20578ebd77d440f1ca47c234502063c52e587a;origin=https://github.com/LMJL-Alea/kAOV;visit=swh:1:snp:a7756669c2a42e4c3998be658e10efa5a25f112c;anchor=swh:1:rev:65d99ffcb8629b2eb799cdfae4a4a64bd28517e5⟩ Logiciel hal-04894520v1
pppca: Principal Component Analysis for replicated point process data. Ghislain Durif,Franck Picard,Vincent Rivoirard,Angelina Roche,Victor Panaretos 2024, ⟨swh:1:dir:89086991867b92ca6d6a574d5ea1856712a60a7f;origin=https://github.com/franckpicard/pppca;visit=swh:1:snp:0ae32effe07f6eb36867b116c91e3b99cbb00acd;anchor=swh:1:rev:9c55bf54091eb823b3f21517728f7abb2e01cc46⟩ Logiciel hal-04894590v1
ktest : two-sample kernel testing Anthony Ozier-Lafontaine,Polina Arsenteva,Ghislain Durif,Franck Picard 2024, ⟨swh:1:dir:669af0c58f89c04be2532e6591eed64de4f4a320;origin=https://github.com/LMJL-Alea/ktest;visit=swh:1:snp:b02da5de23e7a33c50c8159f022c2022426c8d88;anchor=swh:1:rev:54eeffaede8e15bbdef81e5367a691931d6b8171⟩ Logiciel hal-04547380v1
scan10 : Nextflow pipeline for pre-processing and preliminary analysis of single cell RNA-seq data Maxime Lepetit,Laurent Modolo,Franck Picard,Philippe Bertolino 2023, ⟨swh:1:dir:c29f3adcd2cc47cd87dd7f158263bb4d72d101e1;origin=https://gitbio.ens-lyon.fr/LBMC/sbdm/scan10/;visit=swh:1:snp:c9664cb77fa2b68ce8ec656b4fca2cb6dd6b7e82;anchor=swh:1:rev:9b8ee5962601319e3c753d8ee59c231c94a484b6⟩ Logiciel hal-04911084v1

Communication dans un congrès (10)

A Probabilistic Graph Coupling View of Dimension Reduction Hugues van Assel,Thibault Espinasse,Julien Chiquet,Franck Picard Advances in Neural Information Processing Systems, Nov 2022, Nouvelle-Orleans, United States. pp.10696-10708 Communication dans un congrès hal-03548776v3
Probabilistic Count Matrix Factorization for Single Cell Expression Data Analysis Ghislain Durif,Laurent Modolo,Jeff E. Mold,Sophie Lambert-Lacroix,Franck Picard RECOMB 2018 - 22nd Annual International Conference on Research in Computational Molecular Biology, Ecole Polytechnique, Apr 2018, Paris, France. pp.254-255 Communication dans un congrès hal-01962030v1
Fast and parallel algorithm for population-based segmentation of copy-number profiles Guillem Rigaill,Vincent Miele,Franck Picard 10. International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB), Jun 2013, Nice, France. 275 p., ⟨10.1007/978-3-319-09042-9_18⟩ Communication dans un congrès hal-02742012v1
Wavelet-based clustering for mixed-effects functional models Madison Giacofci,Sophie Lambert-Lacroix,Franck Picard 43eme Journées de Statistiques, May 2011, Gammarth, Tunisie Communication dans un congrès hal-00987676v1
Modèle linéaire mixte avec segmentation : application à la détection de changements dans les dates de vendanges Franck Picard,Eva Budinska,Stephane Robin 42. Journées de Statistique, May 2010, Marseille, France Communication dans un congrès hal-01197573v1
Modeling the structure and dynamics of the auxin signaling network in the shoot apical meristem Etienne Farcot,Yann Guédon,Géraldine Brunoud,Jonathan Legrand,Hilde van Den Daeleet al. 6th International Workshop on Functional-Structural Plant Models, 2010, Davis, Canada. pp.146-148 Communication dans un congrès hal-00831786v1
Modèle linéaire mixte avec segmentation : application à la détection de changements dans les dates de vendanges Emilie Lebarbier,Franck Picard,Eva Budinska,Stéphane Robin 42èmes Journées de Statistique, 2010, Marseille, France, France Communication dans un congrès inria-00494861v1
Statistical assessment of chromosomal aberrations at the cohort level: the CGHSeg package Franck Picard,Baba Thiam,Stephane Robin The 5. R useR Conference, Jul 2009, Rennes, France. 18 p Communication dans un congrès hal-01197546v1
Joint segmentation of multivariate Gaussian processes using mixed linear models Franck Picard,Eva Budinska,Stephane S. Robin 12. International Conference on Applied Stochastic Models and Data Analysis, Jun 2007, Chania, Greece Communication dans un congrès hal-02751255v1
Assessing the exceptionality of network motifs Franck Picard,Jean-Jacques Daudin,Michel Koskas,Sophie Schbath,Stephane Robin JOBIM Journées Ouvertes Biologie Informatique Mathématiques, Jul 2007, Marseille, France Communication dans un congrès hal-01197515v1

Rapport (3)

Rapport de conjoncture 2019 : CID 51 Modélisation mathématique, informatique et physique pour les sciences du vivant Franck Picard,Myriam Ferro,Alice Cleynen,Marie Doumic,Xavier Ducheminet al. Comité national de la recherche scientifique. 2020 Rapport hal-04360199v1
A mixture model for random graphs Jean-Jacques Daudin,Franck Picard,Stéphane Robin [Research Report] RR-5840, INRIA. 2006, pp.19 Rapport (rapport de recherche) inria-00070186v1
A statistical approach for CGH microarray data analysis Franck Picard,Stéphane Robin,Marc Lavielle,Christian Vaisse,Gilles Celeuxet al. [Research Report] RR-5139, INRIA. 2004 Rapport (rapport de recherche) inria-00071444v1

Thèse (1)

Process segmentation/clustering. Application to the analysis of CGH microarray data. Franck Picard Mathematics [math]. Université Paris Sud - Paris XI, 2005. English. ⟨NNT : ⟩ Thèse tel-00116025v1