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François Bertucci

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PEC-PRO: A new prognostic score from a series of 87 patients with localized perivascular epithelioid cell neoplasms (PEComas) treated with curative intent

Justine Gantzer , Maud Toulmonde , François Séverac , Ali N. Chamseddine , Celine Charon-Barra
Article dans une revue hal-04533834v1
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PVRIG Expression Is an Independent Prognostic Factor and a New Potential Target for Immunotherapy in Hepatocellular Carcinoma

David Jeremie Birnbaum , Maelle Picard , Quentin da Costa , Thomas Delayre , Pascal Finetti
Cancers, 2023, 15 (2), pp.447. ⟨10.3390/cancers15020447⟩
Article dans une revue hal-03958279v1

Predictive power of tertiary lymphoid structure signature for neoadjuvant chemotherapy response and immunotherapy benefit in HER2‐negative breast cancer

François Bertucci , Alexandre de Nonneville , Pascal Finetti , Emilie Mamessier
Cancer Communications, 2023, 43 (8), pp.943-946. ⟨10.1002/cac2.12447⟩
Article dans une revue hal-04390884v1
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Immunologic constant of rejection as a predictive biomarker of immune checkpoint inhibitors efficacy in non-small cell lung cancer

Alice Mogenet , Pascal Finetti , Emilie Denicolai , Laurent Greillier , Pascaline Boudou-Rouquette
Journal of Translational Medicine, 2023, 21 (1), pp.637. ⟨10.1186/s12967-023-04463-2⟩
Article dans une revue hal-04390901v1
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Sorafenib in Molecularly Selected Cancer Patients: Final Analysis of the MOST-Plus Sorafenib Cohort

Olivier Trédan , Maud Toulmonde , Christophe Le Tourneau , Laure Montane , Antoine Italiano
Article dans une revue hal-04209734v1
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Immunologic constant of rejection as a predictive biomarker of immune checkpoint inhibitors efficacy in non-small cell lung cancer

Alice Mogenet , Pascal Finetti , Emilie Denicolai , Laurent Greillier , Pascaline Boudou-Rouquette
Journal of Translational Medicine, 2023, 21 (1), pp.637. ⟨10.1186/s12967-023-04463-2⟩
Article dans une revue hal-04390234v1

RE: HER2DX ERBB2 mRNA expression in advanced HER2-positive breast cancer treated with T-DM1

François Bertucci , Alexandre de Nonneville , Pascal Finetti , Emilie Mamessier
JNCI: Journal of the National Cancer Institute, 2023, 115 (6), pp.762-763. ⟨10.1093/jnci/djad060⟩
Article dans une revue hal-04390880v1

The MonarchE trial: improving the clinical outcome in HR + /HER2 − early breast cancer: recent results and next steps

François Bertucci , Pascal Finetti , Emilie Mamessier , Alexandre de Nonneville
Cancer Communications, 2023, 43 (8), pp.938-942. ⟨10.1002/cac2.12466⟩
Article dans une revue hal-04390900v1
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Prognostic and Predictive Value of LIV1 Expression in Early Breast Cancer and by Molecular Subtype

Alexandre de Nonneville , Pascal Finetti , Laurys Boudin , Emilie Denicolaï , Daniel Birnbaum
Pharmaceutics, 2023, 15 (3), pp.938. ⟨10.3390/pharmaceutics15030938⟩
Article dans une revue hal-04390874v1
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Identification of Atypical Circulating Tumor Cells with Prognostic Value in Metastatic Breast Cancer Patients

Alexia Lopresti , Claire Acquaviva , Laurys Boudin , Pascal Finetti , Séverine Garnier
Cancers, 2022, 14 (4), pp.932. ⟨10.3390/cancers14040932⟩
Article dans une revue hal-03583233v1

Pathological complete response rate and disease-free survival after neoadjuvant chemotherapy in patients with HER2-low and HER2-0 breast cancers

Alexandre De Nonneville , Gilles Houvenaeghel , Monique Cohen , Laura Sabiani , Marie Bannier
European Journal of Cancer, 2022, 176, pp.181-188. ⟨10.1016/j.ejca.2022.09.017⟩
Article dans une revue hal-04084964v1
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MARCKS as a Potential Therapeutic Target in Inflammatory Breast Cancer

Maroua Manai , Ines Elbini-Dhouib , Pascal Finetti , Haifa Bichiou , Carolina Reduzzi
Cells, 2022, 11 (18), pp.2926. ⟨10.3390/cells11182926⟩
Article dans une revue hal-03958360v1

A 10-miRNA risk score-based prediction model for pathological complete response to neoadjuvant chemotherapy in hormone receptor-positive breast cancer

Chang Gong , Ziliang Cheng , Yaping Yang , Jun Shen , Yingying Zhu
SCIENCE CHINA-LIFE SCIENCES, 2022, 65 (11), pp.2205-2217. ⟨10.1007/s11427-022-2104-3⟩
Article dans une revue hal-04085305v1
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Immunologic constant of rejection signature is prognostic in soft-tissue sarcoma and refines the CINSARC signature

Francois Bertucci , Vincent Niziers , Alexandre de Nonneville , Pascal Finetti , Léna Mescam
Journal for Immunotherapy of Cancer, 2022, 10 (1), pp.e003687. ⟨10.1136/jitc-2021-003687⟩
Article dans une revue hal-03583256v1

First-in-Human, Phase I Study of PCA062 in Solid Tumors—Letter

Bernadette de Rauglaudre , Pascal Finetti , David Jérémie Birnbaum , Marc Lopez , François Bertucci
Molecular Cancer Therapeutics, 2022, 21 (11), pp.1742-1743. ⟨10.1158/1535-7163.MCT-22-0240⟩
Article dans une revue hal-03958336v1

Évolution et facteurs associés à la publication des travaux de thèse d’exercice par les internes d’oncologie médicale en France

Alexandre de Nonneville , F. Bertucci , Éric Lambaudie , Gilles Houvenaeghel , Renaud Sabatier
Bulletin du Cancer, 2022, ⟨10.1016/j.bulcan.2022.01.009⟩
Article dans une revue hal-03623519v1

Repeated Multimodality Ablative Therapies for Oligorecurrent Pulmonary Metastatic Disease

Alban Macagno , Alexandre De Nonneville , Pierre Annede , Gilles Piana , Isabelle Pougnet
CURRENT ONCOLOGY, 2022, 29 (3), pp.1683-1694. ⟨10.3390/curroncol29030140⟩
Article dans une revue hal-04085333v1

RE: NDRG1 in Aggressive Breast Cancer Progression and Brain Metastasis

Alexandre de Nonneville , Pascal Finetti , Emilie Mamessier , François Bertucci
JNCI: Journal of the National Cancer Institute, 2022, ⟨10.1093/jnci/djac031⟩
Article dans une revue hal-03583244v1

Ketogenic HMG‐CoA lyase and its product β‐hydroxybutyrate promote pancreatic cancer progression

Victoire Gouirand , Tristan Gicquel , Evan Lien , Emilie Jaune‐pons , Quentin da Costa
EMBO Journal, 2022, ⟨10.15252/embj.2021110466⟩
Article dans une revue hal-03623502v1

Comparative transcriptional analyses of preclinical models and patient samples reveal MYC and RELA driven expression patterns that define the molecular landscape of IBC

Charlotte Rypens , F. Bertucci , Pascal Finetti , Fredika Robertson , Sandra Fernandez
npj Breast Cancer, 2022, 8 (1), pp.12. ⟨10.1038/s41523-021-00379-6⟩
Article dans une revue hal-03623626v1

Timing evolution of lobular breast cancer through phylogenetic analysis

Danai Fimereli , David Venet , Mattia Rediti , Bram Boeckx , Marion Maetens
EBIOMEDICINE, 2022, 82, ⟨10.1016/j.ebiom.2022.104169⟩
Article dans une revue hal-04084988v1
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Circulating tumor DNA predicts efficacy of a dual AKT/p70S6K inhibitor (LY2780301) plus paclitaxel in metastatic breast cancer: plasma analysis of the TAKTIC phase IB/II study

Renaud Sabatier , Cécile Vicier , Séverine Garnier , Arnaud Guille , Nadine Carbuccia
Molecular Oncology, 2022, 16 (10), pp.2057-2070. ⟨10.1002/1878-0261.13188⟩
Article dans une revue hal-03583253v1

BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells

Violette Azzoni , Julien Wicinski , Manon Macario , Martin Castagné , Pascal Finetti
Cell Death and Disease, 2022, 13 (2), pp.96. ⟨10.1038/s41419-022-04538-w⟩
Article dans une revue hal-03623505v1
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TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT

Alexandre de Nonneville , Sébastien Salas , François Bertucci , Alexander P Sobinoff , José Adélaïde
EMBO Molecular Medicine, 2022, 14, ⟨10.15252/emmm.202215859⟩
Article dans une revue hal-03877721v1
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Loss of primary cilia promotes inflammation and carcinogenesis

Conception Paul , Ruizhi Tang , Ciro Longobardi , Rossano Lattanzio , Thibaut Eguether
EMBO Reports, 2022, ⟨10.15252/embr.202255687⟩
Article dans une revue hal-03856745v1

CSPG4 Expression in GIST Is Associated with Better Prognosis and Strong Cytotoxic Immune Response

Alexandre De Nonneville , Pascal Finetti , Maelle Picard , Audrey Monneur , Maria Abbondanza Pantaleo
Cancers, 2022, 14 (5), ⟨10.3390/cancers14051306⟩
Article dans une revue hal-04085332v1
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CISH Expression Is Associated with Metastasis-Free Interval in Triple-Negative Breast Cancer and Refines the Prognostic Value of PDL1 Expression

Laurys Boudin , Alexandre de Nonneville , Pascal Finetti , Geoffrey Guittard , Jacques Nunes
Cancers, 2022, 14 (14), pp.3356. ⟨10.3390/cancers14143356⟩
Article dans une revue hal-03765362v1
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Investigation of Molecular Features Involved in Clinical Responses and Survival in Advanced Endometrial Carcinoma Treated by Hormone Therapy

Mathias Neron , Arnaud Guille , Lucie Allègre , Pierre-Emmanuel Colombo , Cristina Marinella Leaha
Journal of Personalized Medicine, 2022, 12 (5), pp.655. ⟨10.3390/jpm12050655⟩
Article dans une revue hal-03765663v1
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No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks' Outcome?

Yohan Fayet , Christine Chevreau , Gauthier Decanter , Cécile Dalban , Pierre Méeus
Cancers, 2022, 14 (11), pp.2620. ⟨10.3390/cancers14112620⟩
Article dans une revue hal-03718397v1
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CSPG4 expression in soft tissue sarcomas is associated with poor prognosis and low cytotoxic immune response

Laurys Boudin , A de Nonneville , Pascal Finetti , Léna Mescam , A Le Cesne
Journal of Translational Medicine, 2022, 20 (1), pp.464. ⟨10.1186/s12967-022-03679-y⟩
Article dans une revue hal-03958345v1

Rare bone sarcomas: A retrospective analysis of 145 adult patients from the French Sarcoma Group

Pascaline Boudou‐rouquette , Elodie Martin , Emmanuelle Kempf , Nicolas Penel , Maud Toulmonde
International Journal of Cancer, 2022, 150 (5), pp.825-836. ⟨10.1002/ijc.33837⟩
Article dans une revue hal-03560233v1

Molecular Profiles of Advanced Urological Cancers in the PERMED-01 Precision Medicine Clinical Trial

Émilien Billon , Gwenaelle Gravis , Arnaud Guille , Nadine Carbuccia , José Adélaïde
Cancers, 2022, 14 (9), ⟨10.3390/cancers14092275⟩
Article dans une revue hal-04085310v1

EGFR is a master switch between immunosuppressive and immunoactive tumor microenvironment in inflammatory breast cancer

Xiaoping Wang , Takashi Semba , Ganiraju C. Manyam , Jing Wang , Shan Shao
Science Advances , 2022, 8 (50), ⟨10.1126/sciadv.abn7983⟩
Article dans une revue hal-04084958v1

Comprehensive metabolomics expands precision medicine for triple-negative breast cancer

Yi Xiao , Ding Ma , Yun-Song Yang , Fan Yang , Jia-Han Ding
Article dans une revue hal-03623509v1
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Identification of Atypical Circulating Tumor Cells with Prognostic Value in Metastatic Breast Cancer Patients

Alexia Lopresti , Claire Acquaviva , Laurys Boudin , Pascal Finetti , Séverine Garnier
Cancers, 2022, 14 (4), pp.932. ⟨10.3390/cancers14040932⟩
Article dans une revue hal-03637735v1
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Patterns of care and outcomes of 417 patients with METAstatic SYNovial sarcoma (METASYN): real-life data from the French Sarcoma Group (FSG)

C. Moreau-Bachelard , L. Campion , M. Toulmonde , A. Le Cesne , M. Brahmi
ESMO Open, 2022, 7 (2), pp.100402. ⟨10.1016/j.esmoop.2022.100402⟩
Article dans une revue hal-03623511v1

Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity

Chaïma Cherif , Dang Tan Nguyen , Clément Paris , Thi Khanh Le , Thibaud Sefiane
Oncogene, 2022, 41 (1), pp.125-137. ⟨10.1038/s41388-021-02039-2⟩
Article dans une revue hal-03599176v1
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Immune-Desert Tumor Microenvironment in Thoracic SMARCA4-Deficient Undifferentiated Tumors with Limited Efficacy of Immune Checkpoint Inhibitors

Justine Gantzer , Guillaume Davidson , Bujamin Vokshi , Noëlle Weingertner , Antoine Bougoüin
Article dans une revue hal-03623495v1

Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion

Emilly Villodre , Xiaoding Hu , Richard Larson , Pascal Finetti , Kristen Gomez
Molecular Oncology, 2021, 15 (10), pp.2752-2765. ⟨10.1002/1878-0261.13074⟩
Article dans une revue hal-03623121v1
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Case Report: Grade 2 Metastatic Pancreatic Neuroendocrine Tumor With Progression of One Metastasis After Pregnancy to Grade 3 Large-Cell Neuroendocrine Carcinoma: One Case Cured by Resection With Genomic Characterization of the Two Components

Jean-Luc Raoul , Marie-Françoise Heymann , Frédéric Dumont , Alain Morel , Hélène Senellart
Frontiers in Oncology, 2021, 11, ⟨10.3389/fonc.2021.646992⟩
Article dans une revue hal-03623095v1

Transcriptomic Analysis of Laser Capture Microdissected Tumors Reveals Cancer- and Stromal-Specific Molecular Subtypes of Pancreatic Ductal Adenocarcinoma

David Birnbaum , Sebastian K.S. Begg , Pascal Finetti , Charles Vanderburg , Anupriya Kulkarni
Clinical Cancer Research, 2021, 27 (8), pp.2314-2325. ⟨10.1158/1078-0432.CCR-20-1039⟩
Article dans une revue hal-03623108v1

Alpelisib and fulvestrant efficacy in HR-positive HER2-negative PIK3CA -mutant advanced breast cancer: Data from the French early access program.

F. Bertucci , Diana Bello , Alexandre Bertucci , Thibault de La Motte Rouge , Cyriac Blonz
Journal of Clinical Oncology, 2021, 39 (15_suppl), pp.1064-1064. ⟨10.1200/JCO.2021.39.15_suppl.1064⟩
Article dans une revue hal-03623116v1
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EFA6B regulates a stop signal for collective invasion in breast cancer

Racha Fayad , Monserrat Vázquez Rojas , Mariagrazia Partisani , Pascal Finetti , Shiraz Dib
Nature Communications, 2021, 12, pp.2198. ⟨10.1038/s41467-021-22522-4⟩
Article dans une revue hal-03434635v1
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Expression of X-Linked Inhibitor of Apoptosis Protein (XIAP) in Breast Cancer Is Associated with Shorter Survival and Resistance to Chemotherapy

Gayathri Devi , Pascal Finetti , Michael Morse , Seayoung Lee , Alexandre de Nonneville
Cancers, 2021, 13 (11), pp.2807. ⟨10.3390/cancers13112807⟩
Article dans une revue hal-03623076v1

Cyclin A2 maintains colon homeostasis and is a prognostic factor in colorectal cancer

Yuchen Guo , Monica Gabola , Rossano Lattanzio , Conception Paul , Valérie Pinet
Journal of Clinical Investigation, 2021, 131 (4), ⟨10.1172/JCI131517⟩
Article dans une revue hal-03152320v1

The CINSARC signature predicts the clinical outcome in patients with Luminal B breast cancer

Anthony Goncalves , Pascal Finetti , Daniel Birnbaum , F. Bertucci
npj Breast Cancer, 2021, 7 (1), pp.48. ⟨10.1038/s41523-021-00256-2⟩
Article dans une revue hal-03623055v1
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A single-arm multicentre phase II trial of doxorubicin in combination with trabectedin in the first-line treatment for leiomyosarcoma with long-term follow-up and impact of cytoreductive surgery

P. Pautier , A. Floquet , C. Chevreau , N. Penel , C. Guillemet
ESMO Open, 2021, 6 (4), pp.100209. ⟨10.1016/j.esmoop.2021.100209⟩
Article dans une revue hal-03623631v1

739P Efficacy and safety of maintenance olaparib and bevacizumab (bev) in ovarian cancer (OC) patients (pts) aged ≥65 years (y) from the PAOLA-1/ENGOT-ov25 first-line trial

Renaud Sabatier , Cécile Vicier , Séverine Garnier , Arnaud Guille , Nadine Carbuccia
Annals of Oncology, 2021, 32 (15_suppl), pp.S737-S738. ⟨10.1016/j.annonc.2021.08.1181⟩
Article dans une revue hal-03622737v1
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Metastatic inflammatory breast cancer: survival outcomes and prognostic factors in the national, multicentric, and real-life French cohort (ESME)

D. Dano , A. Lardy-Cleaud , A. Monneur , N. Quenel-Tueux , C. Levy
ESMO Open, 2021, 6 (4), pp.100220. ⟨10.1016/j.esmoop.2021.100220⟩
Article dans une revue hal-03426433v1

TAKTIC: A prospective, multicentre, uncontrolled, phase IB/II study of LY2780301, a p70S6K/AKT inhibitor, in combination with weekly paclitaxel in HER2-negative advanced breast cancer patients

Cecile Vicier , Patrick Sfumato , Nicolas Isambert , Florence Dalenc , Marie Robert
European Journal of Cancer, 2021, 159, pp.205-214. ⟨10.1016/j.ejca.2021.09.040⟩
Article dans une revue hal-03622797v1
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Antisense Oligonucleotide-Based Therapeutic against Menin for Triple-Negative Breast Cancer Treatment

Dang Tan Nguyen , Thi Khanh Le , Clément Paris , Chaïma Cherif , Stéphane Audebert
Biomedicines, 2021, 9 (7), pp.795. ⟨10.3390/biomedicines9070795⟩
Article dans une revue hal-03599175v1
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Quantification of Immune Variables from Liquid Biopsy in Breast Cancer Patients Links Vδ2+ γδ T Cell Alterations with Lymph Node Invasion

Stéphane Fattori , Laurent Gorvel , Samuel Granjeaud , Philippe Rochigneux , Marie-Sarah Rouvière
Cancers, 2021, 13 (3), pp.441. ⟨10.3390/cancers13030441⟩
Article dans une revue hal-03152759v1

Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets

Yue Gong , Peng Ji , Yun-Song Yang , Shao Xie , Tian-Jian Yu
Cell Metabolism, 2021, 33 (1), pp.51-64.e9. ⟨10.1016/j.cmet.2020.10.012⟩
Article dans une revue hal-03623115v1

WEE1 Dependency and Pejorative Prognostic Value in Triple‐Negative Breast Cancer

Alexandre Nonneville , Pascal Finetti , Daniel Birnbaum , Emilie Mamessier , François Bertucci
Advanced Science, 2021, 8 (17), pp.2101030. ⟨10.1002/advs.202101030⟩
Article dans une revue hal-03583269v1

Starting Imatinib at 400 mg Daily in Patients with Gastrointestinal Stromal Tumors Harboring KIT Exon 9 Mutations: A Retrospective, Multicenter Study

Almudena Callejo , Sara Faouzi , Olivier Bouché , F. Bertucci , Thomas Chevalier
Targeted Oncology, 2021, 16 (4), pp.485-492. ⟨10.1007/s11523-021-00820-7⟩
Article dans une revue hal-03623633v1
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A Multicenter Phase II Study of Pazopanib in Patients with Unresectable Dermatofibrosarcoma Protuberans

Julie Delyon , Raphael Porcher , Maxime Battistella , Nicolas Meyer , Henri Adamski
Journal of Investigative Dermatology, 2021, 141 (4), pp.761-769.e2. ⟨10.1016/j.jid.2020.06.039⟩
Article dans une revue hal-03623658v1
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The Evolution and Prognostic Role of Tumour-Infiltrating Lymphocytes and Peripheral Blood-Based Biomarkers in Inflammatory Breast Cancer Patients Treated with Neoadjuvant Chemotherapy

Christophe van Berckelaer , Iris Vermeiren , Leonie Vercauteren , Charlotte Rypens , Gizem Oner
Cancers, 2021, 13 (18), pp.4656. ⟨10.3390/cancers13184656⟩
Article dans une revue hal-03623094v1
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CD44v6 Defines a New Population of Circulating Tumor Cells Not Expressing EpCAM

Guillaume Belthier , Zeinab Homayed , Fanny Grillet , Christophe Duperray , Julie Vendrell
Cancers, 2021, 13 (19), pp.4966. ⟨10.3390/cancers13194966⟩
Article dans une revue hal-03394453v1

Anthracycline-free or short-term regimen as adjuvant chemotherapy for operable breast cancer: A phase III randomized non-inferiority trial

Ke-Da Yu , Xi-Yu Liu , Li Chen , Miao Mo , Jiong Wu
The Lancet Regional Health - Western Pacific, 2021, 11, pp.100158. ⟨10.1016/j.lanwpc.2021.100158⟩
Article dans une revue hal-03623636v1
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LDL receptor-peptide conjugate as in vivo tool for specific targeting of pancreatic ductal adenocarcinoma.

Angélina Acier , Magali Godard , Fanny Gassiot , Pascal Finetti , Marion Rubis
Communications Biology, 2021, 4 (1), pp.987. ⟨10.1038/s42003-021-02508-0⟩
Article dans une revue hal-03452855v1

Immune landscape of inflammatory breast cancer suggests vulnerability to immune checkpoint inhibitors

François Bertucci , Laurys Boudin , Pascal Finetti , Christophe van Berckelaer , Peter van Dam
OncoImmunology, 2021, 10 (1), ⟨10.1080/2162402X.2021.1929724⟩
Article dans une revue hal-03583271v1
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Efficacy and safety of regorafenib in patients with metastatic or locally advanced chondrosarcoma: Results of a non-comparative, randomised, double-blind, placebo controlled, multicentre phase II study

Florence Duffaud , Antoine Italiano , Emannuelle Bompas , Maria Rios , Nicolas Penel
European Journal of Cancer, 2021, 150, pp.108-118. ⟨10.1016/j.ejca.2021.03.039⟩
Article dans une revue hal-03623638v1

CRYODESMO-O1: A prospective, open phase II study of cryoablation in desmoid tumour patients progressing after medical treatment

Jean-Emmanuel Kurtz , Xavier Buy , Frédéric Deschamps , Erik Sauleau , Amine Bouhamama
European Journal of Cancer, 2021, 143, pp.78-87. ⟨10.1016/j.ejca.2020.10.035⟩
Article dans une revue hal-03623642v1

Circulating tumor DNA as a noninvasive marker of resectability in ovarian carcinomas.

Roxane Mari , Christophe Pomel , Pierre-Emmanuel Colombo , Fabrice Narducci , Séverine Garnier
Journal of Clinical Oncology, 2021, 39 (15_suppl), pp.5548-5548. ⟨10.1200/JCO.2021.39.15_suppl.5548⟩
Article dans une revue hal-03622754v1
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Case report: Two cases of metastatic pancreatoblastoma in adults: efficacy of Folfirinox and implication of the wnt/β-catenin pathway in genomic analysis

Jean-Luc Raoul , Sandrine Oziel-Taieb , Thierry Lecomte , José Adelaide , Arnaud Guille
Frontiers in Oncology, 2021, 11, pp.1-8. ⟨10.3389/fonc.2021.564506⟩
Article dans une revue hal-03623119v1
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Prospective high-throughput genome profiling of advanced cancers: results of the PERMED-01 clinical trial

François Bertucci , Anthony Gonçalves , Arnaud Guille , José Adelaïde , Séverine Garnier
Genome Medicine, 2021, 13 (1), pp.87. ⟨10.1186/s13073-021-00897-9⟩
Article dans une revue hal-03583277v1
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Determinants of the access to remote specialised services provided by national sarcoma reference centres

Yohan Fayet , Raphaël Tétreau , Charles Honoré , Louis-Romée Le Nail , Cécile Dalban
BMC Cancer, 2021, 21 (1), pp.631. ⟨10.1186/s12885-021-08393-4⟩
Article dans une revue inserm-03243378v1

The therapeutic response of ER+/HER2− breast cancers differs according to the molecular Basal or Luminal subtype

François Bertucci , Pascal Finetti , Anthony Goncalves , Daniel Birnbaum
npj Breast Cancer, 2020, 6 (1), pp.8. ⟨10.1038/s41523-020-0151-5⟩
Article dans une revue hal-03623676v1

Neoplastic–Stromal Cell Cross-talk Regulates Matrisome Expression in Pancreatic Cancer

Kim Honselmann , Pascal Finetti , David Birnbaum , Christian Monsalve , Ulrich Wellner
Molecular Cancer Research, 2020, 18 (12), pp.1889-1902. ⟨10.1158/1541-7786.mcr-20-0439⟩
Article dans une revue hal-03623660v1
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Santé numérique et « cancer hors les murs », Big Data et intelligence artificielle

Francois Bertucci , Anne-Gaëlle Le Corroller-Soriano , Audrey Monneur , Sylvain Fluzin , Patrice Viens
Bulletin du Cancer, 2020, 107 (1), pp.102-112. ⟨10.1016/j.bulcan.2019.07.006⟩
Article dans une revue hal-02505031v1
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Cancer-testis Antigen FATE1 Expression in Adrenocortical Tumors Is Associated with A Pervasive Autoimmune Response and Is A Marker of Malignancy in Adult, but Not Children, ACC

Mabrouka Doghman-Bouguerra , Pascal Finetti , Nelly Durand , Ivy Zortéa S Parise , Silviu Sbiera
Article dans une revue inserm-02508381v1

A phase II of gemcitabine combined with pazopanib followed by pazopanib maintenance, as second-line treatment in patients with advanced leiomyosarcomas: A unicancer French Sarcoma Group study (LMS03 study)

P. Pautier , N. Penel , I. Ray-Coquard , A. Italiano , E. Bompas
European Journal of Cancer, 2020, 125, pp.31-37. ⟨10.1016/j.ejca.2019.10.028⟩
Article dans une revue hal-02429038v1
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Enhancement of Breast Cancer Cell Aggressiveness by lncRNA H19 and its Mir-675 Derivative: Insight into Shared and Different Actions

Evodie Peperstraete , Clément Lecerf , Jordan Collette , Constance Vennin , Ludivine Raby
Cancers, 2020, 12 (7), pp.1730. ⟨10.3390/cancers12071730⟩
Article dans une revue hal-02896573v1
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Pharmacogenetic Study of Trabectedin-Induced Severe Hepatotoxicity in Patients with Advanced Soft Tissue Sarcoma

Maud Maillard , Christine Chevreau , Félicien Le Louedec , Manon Cassou , Caroline Delmas
Cancers, 2020, 12 (12), pp.3647. ⟨10.3390/cancers12123647⟩
Article dans une revue hal-03623645v1

Characterization of Stromal Tumor-infiltrating Lymphocytes and Genomic Alterations in Metastatic Lobular Breast Cancer

François Richard , Samira Majjaj , David Venet , Françoise Rothé , Julien Pingitore
Clinical Cancer Research, 2020, 26 (23), pp.6254-6265. ⟨10.1158/1078-0432.ccr-20-2268⟩
Article dans une revue hal-03623659v1

NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non‐inflammatory breast cancers

François Bertucci , Charlotte Rypens , Pascal Finetti , Arnaud Guille , José Adélaïde
Molecular Oncology, 2020, 14 (3), pp.504-519. ⟨10.1002/1878-0261.12621⟩
Article dans une revue hal-03623678v1

Genomic landscape of inflammatory breast cancer identifies potential actionable genetic alterations

François Bertucci , Steven Van Laere , Daniel Birnbaum
Oncoscience, 2020, 7 (7-8), pp.57-59. ⟨10.18632/oncoscience.515⟩
Article dans une revue hal-03623667v1
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Revisiting the Concept of Stress in the Prognosis of Solid Tumors: A Role for Stress Granules Proteins?

Anaïs Aulas , Pascal Finetti , Shawn Lyons , François Bertucci , Daniel Birnbaum
Cancers, 2020, 12 (9), pp.2470. ⟨10.3390/cancers12092470⟩
Article dans une revue hal-03606494v1
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PELICAN-IPC 2015-016/Oncodistinct-003: A Prospective, Multicenter, Open-Label, Randomized, Non-Comparative, Phase II Study of Pembrolizumab in Combination With Neo Adjuvant EC-Paclitaxel Regimen in HER2-Negative Inflammatory Breast Cancer

Alexandre Bertucci , F. Bertucci , Christophe Zemmour , Florence Lerebours , Jean-Yves Pierga
Frontiers in Oncology, 2020, 10, ⟨10.3389/fonc.2020.575978⟩
Article dans une revue hal-03623650v1
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SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations

A. Takedachi , E. Despras , S. Scaglione , R. Guérois , J. Guervilly
Nature Structural and Molecular Biology, 2020, 27 (5), pp.438-449. ⟨10.1038/s41594-020-0419-3⟩
Article dans une revue hal-03079782v1
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Revisiting the Concept of Stress in the Prognosis of Solid Tumors: A Role for Stress Granules Proteins?

Anaïs Aulas , Pascal Finetti , Shawn M Lyons , François Bertucci , Daniel Birnbaum
Cancers, 2020, 12 (9), pp.2470. ⟨10.3390/cancers12092470⟩
Article dans une revue hal-02958029v1
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ERBB2b mRNA isoform encodes a nuclear variant of the ERBB2 oncogene in breast cancer

Guoqiang Hua , Aurélie Bergon , Pierre Cauchy , Brigitte Kahn‐perlès , François Bertucci
Journal of Cellular Biochemistry, 2020, ⟨10.1002/jcb.29762⟩
Article dans une revue hal-02897104v1

Combining poly(ADP-ribose) polymerase inhibitors and immune checkpoint inhibitors in breast cancer: rationale and preliminary clinical results

Anthony Goncalves , Essia Mezni , F. Bertucci
Current Opinion in Oncology, 2020, 32 (6), pp.585-593. ⟨10.1097/cco.0000000000000680⟩
Article dans une revue hal-03623648v1
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New Therapeutics in HER2-Positive Advanced Breast Cancer: Towards a Change in Clinical Practices?

Essia Mezni , Cécile Vicier , Mathilde Guerin , Renaud Sabatier , François Bertucci
Cancers, 2020, 12 (6), pp.1573. ⟨10.3390/cancers12061573⟩
Article dans une revue hal-03623669v1

Surgical Margins and Adjuvant Therapies in Malignant Phyllodes Tumors of the Breast: A Multicenter Retrospective Study

Mathias Neron , Christophe Sajous , Simon Thezenas , Sophie Piperno-Neumann , Fabien Reyal
Annals of Surgical Oncology, 2020, 27 (6), pp.1818-1827. ⟨10.1245/s10434-020-08217-y⟩
Article dans une revue hal-03623684v1

Publisher Correction: SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations

A. Takedachi , E. Despras , S. Scaglione , R. Guérois , J. Guervilly
Nature Structural and Molecular Biology, 2020, 27 (6), pp.604-604. ⟨10.1038/s41594-020-0447-z⟩
Article dans une revue hal-02997075v1
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High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies

Maud Toulmonde , Carlo Lucchesi , Stéphanie Verbeke , Amandine Crombe , Julien Adam
EBioMedicine, 2020, 62, ⟨10.1016/j.ebiom.2020.103131⟩
Article dans une revue hal-03034609v1
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Novel Therapeutic Insights in Dedifferentiated Liposarcoma: A Role for FGFR and MDM2 Dual Targeting

Bérengère Dadone-Montaudié , Audrey Laroche-Clary , Aline Mongis , Emmanuel Chamorey , Ilaria Di Mauro
Article dans une revue hal-03034592v1
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PARP Inhibitors in the Treatment of Early Breast Cancer: The Step Beyond?

Anthony Gonçalves , Alexandre Bertucci , François Bertucci
Cancers, 2020, 12 (6), pp.1378. ⟨10.3390/cancers12061378⟩
Article dans une revue hal-03623672v1

Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer—Letter

David Birnbaum , Pascal Finetti , Daniel Birnbaum , F. Bertucci
Clinical Cancer Research, 2020, 26 (20), pp.5539-5539. ⟨10.1158/1078-0432.ccr-20-1969⟩
Article dans une revue hal-03623653v1

Inflammatory breast cancer cells are characterized by abrogated TGFβ1-dependent cell motility and SMAD3 activity

Charlotte Rypens , Melike Marsan , Christophe van Berckelaer , Charlotte Billiet , Kirsten Melis
Breast Cancer Research and Treatment, 2020, 180 (2), pp.385-395. ⟨10.1007/s10549-020-05571-z⟩
Article dans une revue hal-03623677v1
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Quantitative hormone receptor (HR) expression and gene expression analysis in HR+ inflammatory breast cancer (IBC) vs non-IBC

Toshiaki Iwase , Kenichi Harano , Hiroko Masuda , Kumiko Kida , Kenneth R Hess
BMC Cancer, 2020, 20 (1), pp.430. ⟨10.1186/s12885-020-06940-z⟩
Article dans une revue inserm-02913696v1

A double-blind placebo-controlled randomized phase II trial assessing the activity and safety of regorafenib in non-adipocytic sarcoma patients previously treated with both chemotherapy and pazopanib

Nicolas Penel , Olivier Mir , Jennifer Wallet , Isabelle Ray-Coquard , Axel Le Cesne
European Journal of Cancer, 2020, 126, pp.45-55. ⟨10.1016/j.ejca.2019.12.001⟩
Article dans une revue hal-03623680v1
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Infiltrating stromal immune cells in inflammatory breast cancer are associated with an improved outcome and increased PD-L1 expression

C. van Berckelaer , C. Rypens , P. van Dam , L. Pouillon , M. Parizel
Breast Cancer Research, 2019, 21 (1), pp.28. ⟨10.1186/s13058-019-1108-1⟩
Article dans une revue hal-02533387v1
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Programmed cell death 1 (PD-1) targeting in patients with advanced osteosarcomas: results from the PEMBROSARC study

A. Le Cesne , P. Marec-Berard , J.-Y. Blay , N. Gaspar , F. Bertucci
European Journal of Cancer, 2019, 119, pp.151-157. ⟨10.1016/j.ejca.2019.07.018⟩
Article dans une revue hal-02529696v1
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PDL1 expression is associated with longer postoperative, survival in adrenocortical carcinoma

Emilien Billon , Pascal Finetti , Alexandre Bertucci , Patricia Niccoli , Daniel Birnbaum
OncoImmunology, 2019, 8 (11), pp.e1655362. ⟨10.1080/2162402X.2019.1655362⟩
Article dans une revue hal-02509464v1

Common origin of sequential cutaneous CD30+ lymphoproliferations with nodal involvement evidenced by genome-wide clonal evolution

Luc Xerri , José Adelaïde , Morgan Avenin , Arnaud Guille , Sébastien Taix
Histopathology, 2019, 74 (4), pp.654-662. ⟨10.1111/his.13783⟩
Article dans une revue hal-02533424v1

Sensitive and easy screening for circulating tumor cells by flow cytometry

Alexia Lopresti , Fabrice Malergue , François Bertucci , Maria Lucia Liberatoscioli , Séverine Garnier
JCI Insight, 2019, 4 (14), ⟨10.1172/jci.insight.128180⟩
Article dans une revue hal-02529764v1

Author Correction: Genomic characterization of metastatic breast cancers

Francois Bertucci , Charlotte Ng , Anne Patsouris , Nathalie Droin , Salvatore Piscuoglio
Nature, 2019, 572 (7767), pp.E7-E7. ⟨10.1038/s41586-019-1380-3⟩
Article dans une revue hal-02504834v1
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Sarcomas in patients over 90: Natural history and treatment—A nationwide study over 6 years

Clémence Basse , Antoine Italiano , Nicolas Penel , Olivier Mir , Claire Chemin
International Journal of Cancer, 2019, 145 (8), pp.2135-2143. ⟨10.1002/ijc.32307⟩
Article dans une revue hal-02504786v1
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Surgery in reference centers improves survival of sarcoma patients: a nationwide study

J.-Y. Blay , C. Honore , E. Stoeckle , P. Méeus , M. Jafari
Annals of Oncology, 2019, Annals of oncology official journal of the European Society for Medical Oncology, 30 (7), pp.1143-1153. ⟨10.1093/annonc/mdz124⟩
Article dans une revue hal-02509515v1
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Outpatient Cancer Care Delivery in the Context of E-Oncology: A French Perspective on “Cancer outside the Hospital Walls”

François Bertucci , Anne-Gaëlle Le Corroller-Soriano , Audrey Monneur-Miramon , Jean-François Moulin , Sylvain Fluzin
Cancers, 2019, 11 (2), pp.219. ⟨10.3390/cancers11020219⟩
Article dans une revue inserm-02329449v1

Multi-Omics Profiling Reveals Distinct Microenvironment Characterization and Suggests Immune Escape Mechanisms of Triple-Negative Breast Cancer

Yi Xiao , Ding Ma , Shen Zhao , Chen Suo , Jinxiu Shi
Clinical Cancer Research, 2019, 25 (16), pp.5002-5014. ⟨10.1158/1078-0432.CCR-18-3524⟩
Article dans une revue hal-02533431v1
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Epigenetic down-regulation of the HIST1 locus predicts better prognosis in acute myeloid leukemia with NPM1 mutation

Sylvain Garciaz , Lia N’guyen Dasi , Pascal Finetti , Christine Chevalier , Julien Vernerey
Clinical Epigenetics, 2019, 11 (1), ⟨10.1186/s13148-019-0738-6⟩
Article dans une revue hal-02322283v1

Oncogenic states dictate the prognostic and predictive connotations of intratumoral immune response

Jessica Roelands , Wouter Hendrickx , Gabriele Zoppoli , Raghvendra Mall , Mohamad Saad
Journal for Immunotherapy of Cancer, 2019, 8 (1), pp.e000617. ⟨10.1136/jitc-2020-000617⟩
Article dans une revue hal-03623675v1
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Liquid Biopsies for Ovarian Carcinoma: How Blood Tests May Improve the Clinical Management of a Deadly Disease

Roxane Mari , Emilie Mamessier , Eric Lambaudie , Magali Provansal , Daniel Birnbaum
Cancers, 2019, 11 (6), pp.774. ⟨10.3390/cancers11060774⟩
Article dans une revue hal-03606425v1
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Head and Body/Tail Pancreatic Carcinomas Are Not the Same Tumors

David Birnbaum , François Bertucci , Pascal Finetti , Daniel Birnbaum , Emilie Mamessier
Cancers, 2019, 11 (4), pp.497. ⟨10.3390/cancers11040497⟩
Article dans une revue hal-03583447v1

PARP1 expression in soft tissue sarcomas is a poor‐prognosis factor and a new potential therapeutic target

Francois Bertucci , Pascal Finetti , Audrey Monneur , Delphine Perrot , Christine Chevreau
Molecular Oncology, 2019, 13 (7), pp.1577-1588. ⟨10.1002/1878-0261.12522⟩
Article dans une revue hal-02504850v1

Impact of Metastasis Surgery and Alkylating-Agent-Based Chemotherapy on Outcomes of Metastatic Malignant Phyllodes Tumors: A Multicenter Retrospective Study

Mathias Neron , Christophe Sajous , Simon Thezenas , Sophie Piperno-Neumann , Fabien Reyal
Annals of Surgical Oncology, 2019, ⟨10.1245/s10434-019-08097-x⟩
Article dans une revue hal-02530556v1
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Stem Cells Inhibition by Bevacizumab in Combination with Neoadjuvant Chemotherapy for Breast Cancer

Renaud Sabatier , Emmanuelle Charafe-Jauffret , Jean-Yves Pierga , Hervé Curé , Eric Lambaudie
Journal of Clinical Medicine Research, 2019, 8 (5), pp.612. ⟨10.3390/jcm8050612⟩
Article dans une revue hal-02145624v1

MARCKS protein overexpression is associated with poor prognosis in male breast cancer

Maroua Manai , Syrine Abdeljaoued , Aïda Goucha , Olfa Adouni , Ilhem Bettaieb
Cancer Biomarkers, 2019, 26 (4), pp.513-522. ⟨10.3233/CBM-190637⟩
Article dans une revue hal-02530358v1

Validation of Neutrophil Count as An Algorithm-Based Predictive Factor of Progression-Free Survival in Patients with Metastatic Soft Tissue Sarcomas Treated with Trabectedin

Alexandre De Nonneville , Dominique Barbolosi , Maeva Andriantsoa , Raouf El-Cheikh , Florence Duffaud
Contemporary Southeast Asia, 2019, 11 (3), pp.432. ⟨10.3390/cancers11030432⟩
Article dans une revue hal-02461464v1
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PD-1/PD-L1 Targeting in Breast Cancer: The First Clinical Evidences Are Emerging. A Literature Review

Gabrielle Planes-Laine , Philippe Rochigneux , François Bertucci , Anne-Sophie Chrétien , Patrice Viens
Cancers, 2019, 11 (7), pp.1033. ⟨10.3390/cancers11071033⟩
Article dans une revue hal-02533030v1

Major Response to Carboplatin in a Patient With Metastatic Triple-Negative Breast Cancer With Somatic Mutation of BRCA1 and Loss of RAD51B

Lorène Seguin , Max Chaffanet , Séverine Garnier , José Adélaïde , Nadine Carbuccia
JCO precision oncology, 2019, 3, pp.1-9. ⟨10.1200/po.18.00362⟩
Article dans une revue hal-03623688v1

Localized high grade endometrial stromal sarcoma and localized undifferentiated uterine sarcoma: a retrospective series of the French Sarcoma Group

Marie Meurer , A. Floquet , I Ray-Coquard , F. Bertucci , M Auriche
International Journal of Gynecological Cancer, 2019, 29 (4), pp.691-698. ⟨10.1136/ijgc-2018-000064⟩
Article dans une revue hal-02530373v1
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Outpatient Cancer Care Delivery in the Context of E-Oncology: A French Perspective on “Cancer outside the Hospital Walls”

Francois Bertucci , Anne-Gaëlle Le Corroller-Soriano , Audrey Monneur-Miramon , Jean-François Moulin , Sylvain Fluzin
Cancers, 2019, 11 (2), pp.219. ⟨10.3390/cancers11020219⟩
Article dans une revue hal-02504845v1
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Liquid Biopsies for Ovarian Carcinoma: How Blood Tests May Improve the Clinical Management of a Deadly Disease

Roxane Mari , Emilie Mamessier , Eric Lambaudie , Magali Provansal , Daniel Birnbaum
Cancers, 2019, 11 (6), pp.774. ⟨10.3390/cancers11060774⟩
Article dans une revue hal-02152656v1
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A genome-wide RNAi screen reveals essential therapeutic targets of breast cancer stem cells

Abir Arfaoui , Claire Rioualen , Violette Azzoni , Guillaume Pinna , Pascal Finetti
EMBO Molecular Medicine, 2019, 11 (10), pp.e9930. ⟨10.15252/emmm.201809930⟩
Article dans une revue hal-02539524v1

Pathological grade-independent prediction of chemosensitivity by CINSARC should rehabilitate adjuvant chemotherapy in soft tissue sarcomas of any grade

F. Bertucci , P. Finetti , A. Monneur , D. Birnbaum
Annals of Oncology, 2019, 30 (2), pp.342-343. ⟨10.1093/annonc/mdy528⟩
Article dans une revue hal-02505000v1

Overexpression of Annexin A1 Is an Independent Predictor of Longer Overall Survival in Epithelial Ovarian Cancer

Maroua Manai , Raoudha Doghri , Pascal Finetti , Karima Mrad , Rihab Bouabsa
In Vivo, 2019, 34 (1), pp.177-184. ⟨10.21873/invivo.11759⟩
Article dans une revue hal-03623682v1

Successful Imatinib Treatment of an Abdominal Compartment Syndrome due to Huge Gastrointestinal Stromal Tumour

Alexandre Bertucci , Jérôme Guiramand , Lena Mescam , Audrey Monneur , Magali Bisbal
Case Reports in Oncology, 2019, 12 (2), pp.644-649. ⟨10.1159/000502338⟩
Article dans une revue hal-02504820v1
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A Comparison of DNA Mutation and Copy Number Profiles of Primary Breast Cancers and Paired Brain Metastases for Identifying Clinically Relevant Genetic Alterations in Brain Metastases

Marguerite Tyran , Nadine Carbuccia , Séverine Garnier , Arnaud Guille , José Adelaïde
Cancers, 2019, 11 (5), pp.665. ⟨10.3390/cancers11050665⟩
Article dans une revue hal-02533361v1

Genomic characterization of metastatic breast cancers

Francois Bertucci , Charlotte Ng , Anne Patsouris , Nathalie Droin , Salvatore Piscuoglio
Nature, 2019, 569 (7757), pp.560-564. ⟨10.1038/s41586-019-1056-z⟩
Article dans une revue hal-02504838v1
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Pazopanib or methotrexate–vinblastine combination chemotherapy in adult patients with progressive desmoid tumours (DESMOPAZ): a non-comparative, randomised, open-label, multicentre, phase 2 study

Maud Toulmonde , Marina Pulido , Isabelle Ray-Coquard , Thierry André , Nicolas Isambert
Lancet Oncology, 2019, 20 (9), pp.1263-1272. ⟨10.1016/S1470-2045(19)30276-1⟩
Article dans une revue hal-02533355v1

ESR1 mutations in metastatic lobular breast cancer patients

Christine Desmedt , Julien Pingitore , Françoise Rothé , Caterina Marchio , Florian Clatot
npj Breast Cancer, 2019, 5 (1), ⟨10.1038/s41523-019-0104-z⟩
Article dans une revue hal-02352890v1

Results of API–AI based regimen in osteosarcoma adult patients included in the French OS2006/Sarcome‐09 study

Sophie Piperno-Neumann , Isabelle Ray-Coquard , Bob-Valéry Occean , Valérie Laurence , Didier Cupissol
International Journal of Cancer, 2019, 146 (2), pp.413-423. ⟨10.1002/ijc.32526⟩
Article dans une revue hal-02530602v1

Can we cure patients with abdominal Desmoplastic Small Round Cell Tumor? Results of a retrospective multicentric study on 100 patients

C. Honore , J.B. Delhorme , E. Nassif , M. Faron , G. Ferron
Surgical Oncology, 2019, 29, pp.107-112. ⟨10.1016/j.suronc.2019.04.002⟩
Article dans une revue hal-02528457v1

PDL1 expression is associated with longer postoperative, survival in adrenocortical carcinoma

Emilien Billon , Pascal Finetti , Alexandre Bertucci , Patricia Niccoli , Daniel Birnbaum
OncoImmunology, 2019, 8 (11), pp.e1655362. ⟨10.1080/2162402X.2019.1655362⟩
Article dans une revue hal-03606482v1

High Response to Cetuximab in a Patient With EGFR -Amplified Heavily Pretreated Metastatic Triple-Negative Breast Cancer

Renaud Sabatier , Marc Lopez , Arnaud Guille , Emilien Billon , Nadine Carbuccia
JCO precision oncology, 2019, 3, pp.1-8. ⟨10.1200/po.18.00310⟩
Article dans une revue hal-03623686v1
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A Tyrosine Kinase Expression Signature Predicts the Post-Operative Clinical Outcome in Triple Negative Breast Cancers

Alexandre de Nonneville , Pascal Finetti , José Adelaïde , Eric Lambaudie , Patrice Viens
Cancers, 2019, 11 (8), pp.1158. ⟨10.3390/cancers11081158⟩
Article dans une revue hal-02518929v1
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ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer

Luc Camoin , Jean-Paul Borg , Avais M Daulat , Pascal Finetti , Diego R Revinski
British Journal of Cancer, 2019, 120 (9), pp.931-940. ⟨10.1038/s41416-019-0448-z⟩
Article dans une revue hal-02145896v1
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XPO1 Expression Is a Poor-Prognosis Marker in Pancreatic Adenocarcinoma

David Jérémie Birnbaum , Pascal Finetti , Daniel Birnbaum , Emilie Mamessier , Francois Bertucci
Journal of Clinical Medicine, 2019, 8 (5), pp.596. ⟨10.3390/jcm8050596⟩
Article dans une revue hal-02509509v1

Inflammatory breast cancer in 210�patients: A retrospective study on epidemiological, anatomo‑clinical features and therapeutic results

Maroua Manai , Pascal Finetti , Nesrine Mejri , Salma Athimni , Daniel Birnbaum
Molecular and Clinical Oncology, 2018, 10 (2), pp.223-230. ⟨10.3892/mco.2018.1773⟩
Article dans une revue hal-02530356v1

The immunologic constant of rejection classification refines the prognostic value of conventional prognostic signatures in breast cancer

François Bertucci , Pascal Finetti , Ines Simeone , Wouter Hendrickx , Ena Wang
British Journal of Cancer, 2018, 119 (11), pp.1383-1391. ⟨10.1038/s41416-018-0309-1⟩
Article dans une revue hal-03606514v1

``Wnt/beta-Catenin in GIST''-Letter

Francois Bertucci , Pascal Finetti , Alexandre de Nonneville , Daniel Birnbaum
MOLECULAR CANCER THERAPEUTICS, 2018, 17 (1), pp.327-328. ⟨10.1158/1535-7163.MCT-17-0948⟩
Article dans une revue hal-02143618v1
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Targeting BRCA Deficiency in Breast Cancer: What are the Clinical Evidences and the Next Perspectives?

Emanuel Nicolas , Francois Bertucci , Renaud Sabatier , Anthony Goncalves
Cancers, 2018, 10 (12), ⟨10.3390/cancers10120506⟩
Article dans une revue hal-02143625v1
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The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/beta-Catenin Signaling

Leonor Lopez Almeida , Michael Sebbagh , Francois Bertucci , Pascal Finetti , Julien Wicinski
Stem Cell Reports, 2018, 11 (5), pp.1040-1050. ⟨10.1016/j.stemcr.2018.09.008⟩
Article dans une revue hal-02143631v1

The immunologic constant of rejection classification refines the prognostic value of conventional prognostic signatures in breast cancer

Francois Bertucci , Pascal Finetti , Ines Simeone , Wouter Hendrickx , Ena Wang
Breast Cancer Research and Treatment, 2018, 119 (11), pp.1383-1391. ⟨10.1038/s41416-018-0309-1⟩
Article dans une revue hal-02143596v1

Impact of Trabectedin Interruption and Subsequent Rechallenge on Progression in Patients With Advanced Soft Tissue Sarcoma

Nuria Kotecki , Axel Le Cesne , Emmanuelle Tresch-Bruneel , Isabelle Ray-Coquard , Christine Chevreau
American Journal of Clinical Oncology, 2018, 41 (11), pp.1094-1100. ⟨10.1097/coc.0000000000000430⟩
Article dans une revue hal-03623697v1

A major response to carboplatin in a metastatic triple-negative breast cancer patient with somatic mutation of BRCA1 and RAD51B: When chemotherapy meets precision medicine

L. Seguin , M. Chaffanet , R. Sabatier , A. Jose , S. Garnier
Annals of Oncology, 2018, 29 (6), ⟨10.1093/annonc/mdy314.030⟩
Article dans une revue hal-02143656v1

Determinants of favorable or unfavorable opinion about euthanasia in a sample of French cancer patients receiving palliative care

Alexandre de Nonneville , François Bertucci , Pascal Finetti , D. Perrot , M. Nilbert
BMC Palliative Care, 2018, 17 (1), pp.104. ⟨10.1186/s12904-018-0357-6⟩
Article dans une revue hal-03583406v1
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Stromal Expression of MARCKS Protein in Ovarian Carcinomas Has Unfavorable Prognostic Value

Raoudha Doghri , Maroua Manai , Pascal Finetti , Maha Driss , Emilie Agavnian
International Journal of Molecular Sciences, 2018, 19 (1), ⟨10.3390/ijms19010041⟩
Article dans une revue hal-02143620v1
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Development of parallel reaction monitoring (PRM)-based quantitative proteomics applied to HER2-Positive breast cancer

Mathilde Guérin , Anthony Gonçalves , Yves Toiron , Emilie Baudelet , Matthieu Pophillat
Oncotarget, 2018, 9 (73), pp.33762-33777. ⟨10.18632/oncotarget.26031⟩
Article dans une revue hal-02145636v1

Metastatic Intimal Sarcoma of the Pulmonary Artery Sensitive to Carboplatin-Vinorelbine Chemotherapy: Case Report and Literature Review

Marie Cantaloube , Laurence Moureau-Zabotto , Lena Mescam , Audrey Monneur , Valeria Deluca
Case Reports in Oncology, 2018, 11 (1), pp.21-28. ⟨10.1159/000485740⟩
Article dans une revue hal-02143619v1

Giant Pedunculated Hepatic Hemangioma: A Case Report and Literature Review

Abdallah  Al farai , Lénaïg Mescam , Valeria De luca , Audrey Monneur , Delphine Perrot
Case Reports in Oncology, 2018, 11 (2), pp.476-484. ⟨10.1159/000490696⟩
Article dans une revue hal-03623704v1

Localized Myxofibrosarcomas: Roles of Surgical Margins and Adjuvant Radiation Therapy

Raoudha Boughzala-Bennadji , Eberhard Stoeckle , Cécile Le Péchoux , Pierre Méeus , Charles Honoré
International Journal of Radiation Oncology, Biology, Physics, 2018, 102 (2), pp.399-406. ⟨10.1016/j.ijrobp.2018.05.055⟩
Article dans une revue hal-02049039v1

The Genomic Grade Index predicts postoperative clinical outcome in patients with soft-tissue sarcoma

F Bertucci , A de Nonneville , P Finetti , D Perrot , M Nilbert
Annals of Oncology, 2018, 29 (2), pp.459 - 465. ⟨10.1093/annonc/mdx699⟩
Article dans une revue hal-01787485v1

Efficacy and safety of regorafenib compared to placebo and to post-cross-over regorafenib in advanced non-adipocytic soft tissue sarcoma

Christine Desmedt , Roberto Salgado , Marco Fornili , Giancarlo Pruneri , Gert van den Eynden
European Journal of Cancer, 2018, 99 (7), pp.28-36. ⟨10.1016/j.ejca.2018.05.008⟩
Article dans une revue hal-03623702v1

CDKN2A/B Deletion and Double-hit Mutations of the MAPK Pathway Underlie the Aggressive Behavior of Langerhans Cell Tumors

Luc Xerri , José Adelaïde , Cornel Popovici , Séverine Garnier , Arnaud Guille
American Journal of Surgical Pathology, 2018, 42 (2), pp.150 - 159. ⟨10.1097/PAS.0000000000000989⟩
Article dans une revue hal-01788565v1
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Rates of immune cell infiltration in patients with triple-negative breast cancer by molecular subtype

Kenichi Harano , Ying Wang , Bora Lim , Robert S. Seitz , Stephan W. Morris
PLoS ONE, 2018, 13 (10), pp.e0204513. ⟨10.1371/journal.pone.0204513⟩
Article dans une revue hal-02143557v1

Poly (ADP-Ribose) Polymerase Inhibitors for De Novo BRCA2-Null Small-Cell Prostate Cancer

Brice Chanez , Max Chaffanet , José Adélaide , Jeanne Thomassin , Séverine Garnier
JCO precision oncology, 2018, 2, pp.1-8. ⟨10.1200/po.18.00083⟩
Article dans une revue hal-03623699v1

Molecular classification as prognostic factor and guide for treatment decision of pancreatic cancer

David Birnbaum , François Bertucci , Pascal Finetti , Daniel Birnbaum , Emilie Mamessier
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2018, 1869 (2), pp.248-255. ⟨10.1016/j.bbcan.2018.02.001⟩
Article dans une revue hal-03583468v1
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Targeting BRCA Deficiency in Breast Cancer: What are the Clinical Evidences and the Next Perspectives?

Emanuel Nicolas , François Bertucci , Renaud Sabatier , Anthony Gonçalves
Cancers, 2018, 10 (12), pp.506. ⟨10.3390/cancers10120506⟩
Article dans une revue hal-03669695v1
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Safety Results and Analysis of Eribulin Efficacy according to Previous Microtubules-Inhibitors Sensitivity in the French Prospective Expanded Access Program for Heavily Pre-treated Metastatic Breast Cancer

Renaud Sabatier , Véronique Diéras , Xavier B. Pivot , Etienne Brain , Henri Roche
Breast Cancer Research and Treatment, 2018, 50 (4), pp.1226-1237. ⟨10.4143/crt.2017.446⟩
Article dans une revue inserm-01985845v1

EPIGIST: An observational real-life study on patients with metastatic gastrointestinal stromal tumors receiving imatinib

Olivier Bouché , Axel Le Cesne , Maria Rios , Loic Chaigneau , Antoine Italiano
PLoS ONE, 2018, 13 (9), pp.e0204117. ⟨10.1371/journal.pone.0204117⟩
Article dans une revue hal-02005925v1

Reversible rituximab-induced rectal Kaposi's sarcoma misdiagnosed as ulcerative colitis in a patient with HIV-negative follicular lymphoma

Emilien Billon , Anne-Marie Stoppa , Lena Mescam , Massimo Bocci , Audrey Monneur
CLINICAL SARCOMA RESEARCH, 2018, 8, ⟨10.1186/s13569-018-0097-7⟩
Article dans une revue hal-02143666v1

Ex vivo CSC assays for personalized testing of drug susceptibility in advanced breast cancer

Emmanuelle Charafe-Jauffret , Julien Wicinski , Olivier Cabaud , Marc Lopez , Stephane Audebert
Cancer Research, 2018, 78 (4, S)
Article dans une revue hal-02143678v1

CMTM6 stabilizes PD-L1 expression and refines its prognostic value in tumors

Emilie Mamessier , David Birnbaum , Pascal Finetti , Daniel Birnbaum , François Bertucci
Annals of translational medicine, 2018, 6 (3), pp.54 - 54. ⟨10.21037/atm.2017.11.26⟩
Article dans une revue hal-01765411v1

PD-L1 expression and PD-1/PD-L1 inhibitors in breast cancer

Audrey Monneur , Anthony Goncalves , Francois Bertucci
Bulletin du Cancer, 2018, 105 (3), pp.261-272. ⟨10.1016/j.bulcan.2017.11.012⟩
Article dans une revue hal-02143676v1
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Prognostic and predictive factors for angiosarcoma patients receiving paclitaxel once weekly plus or minus bevacizumab: an ancillary study derived from a randomized clinical trial

Loïc Lebellec , François Bertucci , Emmanuelle Tresch-Bruneel , Isabelle Ray-Coquard , Axel Le Cesne
BMC Cancer, 2018, 18 (1), pp.963. ⟨10.1186/s12885-018-4828-1⟩
Article dans une revue inserm-02050851v1
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Regosarc: regorafenib versus placebo in doxorubicin-refractory soft-tissue sarcoma-a quality-adjusted time without symptoms of progression or toxicity analysis

Vincent Berry , Laurent Basson , Emilie Bogart , Olivier Mir , Jean-Yves Blay
Cancer, 2017, Cancer, 123, pp.2294-2302. ⟨10.1002/cncr.30661⟩
Article dans une revue hal-02638646v1
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Characterization and Targeting of Platelet-Derived Growth Factor Receptor alpha (PDGFRA) in Inflammatory Breast Cancer (IBC)

Madhura Joglekar-Javadekar , Steven van Laere , Michael Bourne , Manal Moalwi , Pascal Finetti
Neoplasia, 2017, 19 (7), pp.564-573. ⟨10.1016/j.neo.2017.03.002⟩
Article dans une revue hal-01789694v1
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A retrospective multicentric study of ewing sarcoma family of tumors in patients older than 50: management and outcome

Pauline Rochefort , Antoine Italiano , Valérie Laurence , Nicolas Penel , Audrey Lardy-Cleaud
Scientific Reports, 2017, Scientific reports, 7, ⟨10.1038/s41598-017-17733-z⟩
Article dans une revue hal-02613645v1

A scoring system to guide the decision for a new systemic treatment after at least two lines of palliative chemotherapy for metastatic cancers: a prospective study

Brice Chanez , François Bertucci , Marine Gilabert , Anne Madroszyk , Frédérique Rousseau
Supportive Care in Cancer, 2017, 25 (9), pp.2715-2722. ⟨10.1007/s00520-017-3680-1⟩
Article dans une revue hal-03623718v1

Prediction of local and metastatic recurrence in solitary fibrous tumor: construction of a risk calculator in a multicenter cohort from the French Sarcoma Group (FSG) database

S. Salas , N. Resseguier , Jean-Yves Blay , A. Le Cesne , A. Italiano
Annals of Oncology, 2017, 28 (8), pp.1979 - 1987. ⟨10.1093/annonc/mdx250⟩
Article dans une revue hal-01655970v1

Prognostic Value of Molecular Subtypes in Pancreatic Cancer

François Bertucci , David Birnbaum , Pascal Finetti , Marine Gilabert , Flora Poizat
Pancreas, 2017, 46 (4), pp.e29-e31. ⟨10.1097/MPA.0000000000000787⟩
Article dans une revue hal-03606452v1
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A 25-gene classifier predicts overall survival in resectable pancreatic cancer

David Birnbaum , Pascal Finetti , Alexia Lopresti , Marine Gilabert , Flora Poizat
BMC Medicine, 2017, 15 (1), ⟨10.1186/s12916-017-0936-z⟩
Article dans une revue hal-01787872v1

Wnt Signaling Inhibition Promotes Apoptosis in Sarcomas—Letter

François Bertucci , Pascal Finetti , Daniel Birnbaum
Molecular Cancer Therapeutics, 2017, 16 (10), pp.2324 - 2324. ⟨10.1158/1535-7163.MCT-17-0491⟩
Article dans une revue hal-01787271v1

Gastrointestinal Stromal Tumour with Synchronous Bone Metastases: A Case Report and Literature Review

Philippe Rochigneux , Lénaig Mescam-Mancini , Delphine Perrot , Erwan Bories , Laurence Moureau-Zabotto
Case Reports in Oncology, 2017, 10 (1), pp.66-76. ⟨10.1159/000455188⟩
Article dans une revue hal-03623722v1
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miR-600 Acts as a Bimodal Switch that Regulates Breast Cancer Stem Cell Fate through WNT Signaling

Rita El Helou , Guillaume Pinna , Olivier Cabaud , Julien Wicinski , Ricky Bhajun
Cell Reports, 2017, 18 (9), pp.2256-2268. ⟨10.1016/j.celrep.2017.02.016⟩
Article dans une revue hal-01789620v1

[Impact of Her2 and BRCA1/2 status in high-dose chemotherapy and autologous stem cells transplantation in the treatment of breast cancer: The Institut Paoli Calmettes' experience].

Laurys Boudin , Christian Chabannon , Patrick Sfumato , Renaud Sabatier , François Bertucci
Bulletin du Cancer, 2017, 104 (4), pp.332 - 343. ⟨10.1016/j.bulcan.2016.12.007⟩
Article dans une revue hal-01788977v1

An ICGC major achievement in breast cancer: a comprehensive catalog of mutations and mutational signatures

François Bertucci , Max Chaffanet , Daniel Birnbaum
Chinese Clinical Oncology, 2017, 6 (1), pp.4 - 4. ⟨10.21037/cco.2016.11.01⟩
Article dans une revue hal-01787356v1

Erratum to: HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers

Preeti Putcha , Jiyang Yu , Ruth Rodriguez-Barrueco , Laura Saucedo-Cuevas , Patricia Villagrasa
Breast Cancer Research, 2017, 19 (1), pp.49. ⟨10.1186/s13058-017-0841-6⟩
Article dans une revue hal-03623716v1
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Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis

Wouter Hendrickx , Ines Simeone , Samreen Anjum , Younes Mokrab , François Bertucci
OncoImmunology, 2017, 6 (2), ⟨10.1080/2162402X.2016.1253654⟩
Article dans une revue hal-01788951v1
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MARCKS protein overexpression in inflammatory breast cancer

Maroua Manai , Jeanne Thomassin-Piana , Amor Gamoudi , Pascal Finetti , Marc Lopez
Oncotarget, 2017, 8, pp.6246 - 6257. ⟨10.18632/oncotarget.14057⟩
Article dans une revue hal-01787705v1

Surgical versus non-surgical approach in primary desmoid-type fibromatosis patients: A nationwide prospective cohort from the French Sarcoma Group

Nicolas Penel , Axel Le Cesne , Sylvie Bonvalot , Antoine Giraud , Emmanuelle Bompas
European Journal of Cancer, 2017, 83, pp.125-131. ⟨10.1016/j.ejca.2017.06.017⟩
Article dans une revue hal-03623713v1
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Circulating Tumour Cells and pathological complete response: independent prognostic factors in inflammatory breast cancer in a pooled analysis of two multicentre phase II trials (BEVERLY-1 and -2) of neoadjuvant chemotherapy combined with bevacizumab

Jean-Yves Pierga , François-Clément Bidard , A. Autret , Tillys Petit , Frédéric André
Annals of Oncology, 2017, 28, pp.mdw535. ⟨10.1093/annonc/mdw535⟩
Article dans une revue inserm-01985299v1
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Validation and comparison of the molecular classifications of pancreatic carcinomas

David Birnbaum , Pascal Finetti , Daniel Birnbaum , Emilie Mamessier , François Bertucci
Molecular Cancer, 2017, 16 (1), pp.168. ⟨10.1186/s12943-017-0739-z⟩
Article dans une revue hal-03583469v1

The use of systemic therapies to prevent progression of inflammatory breast cancer: which targeted therapies to add on cytotoxic combinations?

Anthony Gonçalves , Audrey Monneur , Patrice Viens , François Bertucci
Expert Review of Anticancer Therapy, 2017, 17 (7), pp.593-606. ⟨10.1080/14737140.2017.1330655⟩
Article dans une revue hal-03623715v1
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Nectin-4: a new prognostic biomarker for efficient therapeutic targeting of primary and metastatic triple-negative breast cancer

M. M-Rabet , O. Cabaud , E. Josselin , P. Finetti , R. Castellano
Annals of Oncology, 2017, ⟨10.1093/annonc/mdw678⟩
Article dans une revue hal-01787533v1

Adjuvant chemotherapy in pT1ab node-negative triple-negative breast carcinomas: Results of a national multi-institutional retrospective study

A. de Nonneville , A. Goncalves , C. Zemmour , M. Cohen , J.M. Classe
European Journal of Cancer, 2017, 84, pp.34-43. ⟨10.1016/j.ejca.2017.06.043⟩
Article dans une revue hal-02282824v1

A stemness-related ZEB1–MSRB3 axis governs cellular pliancy and breast cancer genome stability

Anne Morel , Christophe Ginestier , Roxane Pommier , Olivier Cabaud , Emmanuelle Ruiz
Nature Medicine, 2017, 23 (5), pp.568 - 578. ⟨10.1038/nm.4323⟩
Article dans une revue hal-01788395v1
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miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy

Ruth Rodriguez-Barrueco , Erin A Nekritz , François Bertucci , Jiyang Yu , Felix Sanchez-Garcia
Genes and Development, 2017, 31 (6), pp.553-566. ⟨10.1101/gad.292318.116⟩
Article dans une revue hal-01787959v1

PIKHER2: A phase IB study evaluating buparlisib in combination with lapatinib in trastuzumab-resistant HER2-positive advanced breast cancer

Mathilde Guerin , Keyvan Rezai , Nicolas Isambert , Mario Campone , Aurélie Autret
European Journal of Cancer, 2017, 86, pp.28-36. ⟨10.1016/j.ejca.2017.08.025⟩
Article dans une revue hal-03623711v1

Benefit of adjuvant chemotherapy with or without trastuzumab in pT1ab node-negative human epidermal growth factor receptor 2-positive breast carcinomas: results of a national multi-institutional study

Alexandre de Nonneville , Anthony Gonçalves , Christophe Zemmour , Jean Classe , Monique Cohen
Breast Cancer Research and Treatment, 2017, 162 (2), pp.307-316. ⟨10.1007/s10549-017-4136-5⟩
Article dans une revue hal-03623719v1

Advanced chordoma treated by first-line molecular targeted therapies: Outcomes and prognostic factors. A retrospective study of the French Sarcoma Group (GSF/GETO) and the Association des Neuro-Oncologues d'Expression Française (ANOCEF)

Loïc Lebellec , Bruno Chauffert , Jean-Yves Blay , Axel Le Cesne , Christine Chevreau
European Journal of Cancer, 2017, 79, pp.119 - 128. ⟨10.1016/j.ejca.2017.03.037⟩
Article dans une revue hal-01655981v1
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Similar response profile to neoadjuvant chemotherapy, but different survival, in inflammatory versus locally advanced breast cancers

Audrey Monneur , Anthony Gonçalves , Marine Gilabert , Pascal Finetti , Carole Tarpin
Oncotarget, 2017, 8 (39), pp.66019 - 66032. ⟨10.18632/oncotarget.19732⟩
Article dans une revue inserm-01984755v1

Scientific summary from the Morgan Welch MD Anderson Cancer Center Inflammatory Breast Cancer (IBC) program 10th Anniversary Conference

Wendy Woodward , Massimo Cristofanilli , Sofia Merajver , Steven van Laere , Lajos Pusztai
Journal of Cancer, 2017, 8 (17), pp.3607-3614. ⟨10.7150/jca.21200⟩
Article dans une revue hal-03623708v1

Immunotherapy in Breast Cancer: the Emerging Role of PD-1 and PD-L1

François Bertucci , Anthony Gonçalves
Current Oncology Reports, 2017, 19 (10), pp.64. ⟨10.1007/s11912-017-0627-0⟩
Article dans une revue hal-03623712v1
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Nectine-4 : un biomarqueur pronostique et une cible thérapeutique potentielle dans le cancer du sein triple-négatif

Manel M 'Rabet , François Bertucci , Daniel Birnbaum , Marc Lopez
Médecine/Sciences, 2017
Article dans une revue hal-01788721v1

PDL1 expression is a poor-prognosis factor in soft-tissue sarcomas

François Bertucci , Pascal Finetti , Delphine Perrot , Agnès Leroux , Françoise Collin
OncoImmunology, 2017, 6 (3), pp.e1278100. ⟨10.1080/2162402X.2016.1278100⟩
Article dans une revue hal-01765418v1

SPAG5: the ultimate marker of proliferation in early breast cancer?

François Bertucci , Patrice Viens , Daniel Birnbaum
Lancet Oncology, 2016, 17 (7), pp.863-865. ⟨10.1016/s1470-2045(16)30092-4⟩
Article dans une revue hal-03623730v1
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Prognostic value of PDL1 expression in pancreatic cancer

David Birnbaum , Pascal Finetti , Alexia Lopresti , Marine Gilabert , Flora Poizat
Oncotarget, 2016, 7 (44), ⟨10.18632/oncotarget.11685⟩
Article dans une revue hal-01765421v1
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Pregnane X-receptor promotes stem cell-mediated colon cancer relapse

Chris Planque , Fatemeh Rajabi , Fanny Grillet , Pascal Finetti , François Bertucci
Oncotarget, 2016, 7 (35), pp.56558-56573. ⟨10.18632/oncotarget.10646⟩
Article dans une revue hal-01431926v1

XPO1, therapeutic...and prognostic target in sarcomas

François Bertucci , Pascal Finetti , Daniel Birnbaum
Oncoscience, 2016, 3 (5-6), pp.143-144. ⟨10.18632/oncoscience.304⟩
Article dans une revue hal-03623732v1

Genomic Characterization of Primary Invasive Lobular Breast Cancer

Christine Desmedt , Gabriele Zoppoli , Gunes Gundem , Giancarlo Pruneri , Denis Larsimont
Journal of Clinical Oncology, 2016, 34 (16), pp.1872-1881. ⟨10.1200/jco.2015.64.0334⟩
Article dans une revue hal-03623737v1

Long-term outcome of molecular subgroups of GIST patients treated with standard-dose imatinib in the BFR14 trial of the French Sarcoma Group

A. Patrikidou , J. Domont , Sylvie Chabaud , Isabelle Ray-Coquard , J.M. Coindre
European Journal of Cancer, 2016, 52, pp.173--180. ⟨10.1016/j.ejca.2015.10.069⟩
Article dans une revue hal-01812685v1

Targeted NGS, array-CGH, and patient-derived tumor xenografts for precision medicine in advanced breast cancer: a single-center prospective study

Anthony Gonçalves , François Bertucci , Arnaud Guille , Severine Garnier , José Adelaide
Oncotarget, 2016, 7 (48), pp.79428-79441. ⟨10.18632/oncotarget.12714⟩
Article dans une revue hal-03623724v1

Molecular targeted therapies (MTT) in advanced chordoma (AC) patients (pts).

Loic Lebellec , Axel Le Cesne , Nicolas Penel , Jean -Yves Blay , Christine Chevreau
Journal of Clinical Oncology, 2016, 34 (15, S), ⟨10.1200/JCO.2016.34.15\_suppl.11020⟩
Article dans une revue hal-03598684v1

Corrigendum to “Immunohistochemical subtypes predict survival in metastatic breast cancer receiving high-dose chemotherapy with autologous haematopoietic stem cell transplantation” [Eur J Cancer 57 (April 2016) 118–126]

Laurys Boudin , Christian Chabannon , Patrick Sfumato , Renaud Sabatier , François Bertucci
European Journal of Cancer, 2016, 67, pp.223. ⟨10.1016/j.ejca.2016.09.002⟩
Article dans une revue hal-03623727v1

Bevacizumab plus neoadjuvant chemotherapy in patients with HER2-negative inflammatory breast cancer (BEVERLY-1): a multicentre, single-arm, phase 2 study

François Bertucci , Mahmoud Fekih , Aurélie Autret , Thierry Petit , Florence Dalenc
Lancet Oncology, 2016, 17 (5), pp.600-611. ⟨10.1016/s1470-2045(16)00011-5⟩
Article dans une revue hal-03623735v1

Bevacizumab in HER2-negative inflammatory breast cancer

François Bertucci , Anthony Goncalves , Patrice Viens
Oncoscience, 2016, 3 (11-12), pp.297-298. ⟨10.18632/oncoscience.324⟩
Article dans une revue hal-03623723v1

Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem-like Cells

Julie Giraud , Laura Failla , Jean-Marc Pascussi , Ebba Louise Lagerqvist , Jérémy Ollier
Cancer Research, 2016, 76 (12), pp.3618 - 3628. ⟨10.1158/0008-5472.CAN-15-1497⟩
Article dans une revue hal-01905320v1
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Expression of Genes with Copy Number Alterations and Survival of Patients with Pancreatic Adenocarcinoma.

David Birnbaum , François Bertucci , Pascal Finetti , José Adélaïde , Marc Giovannini
Cancer Genomics and Proteomics, 2016, 13 (3), pp.191-200
Article dans une revue hal-03583479v1

MMP2 and MMP9 serum levels are associated with favorable outcome in patients with inflammatory breast cancer treated with bevacizumab-based neoadjuvant chemotherapy in the BEVERLY-2 study

Emeline Tabouret , François Bertucci , Jean-Yves Pierga , Thierry Petit , Christelle Levy
Oncotarget, 2016, 7 (14), pp.18531-18540. ⟨10.18632/oncotarget.7612⟩
Article dans une revue hal-03623733v1

Pazopanib plus best supportive care versus best supportive care alone in advanced gastrointestinal stromal tumours resistant to imatinib and sunitinib (PAZOGIST): a randomised, multicentre, open-label phase 2 trial

Olivier Mir , Claire Cropet , Maud Toulmonde , Axel Le Cesne , Mathieu Molimard
Lancet Oncology, 2016, 17 (5), pp.632-641. ⟨10.1016/s1470-2045(16)00075-9⟩
Article dans une revue hal-03623734v1

Management of desmoid tumours: A nationwide survey of labelled reference centre networks in France

N. Penel , J.M. Coindre , S. Bonvalot , A. Italiano , A. Neuville
European Journal of Cancer, 2016, 58, pp.90--96. ⟨10.1016/j.ejca.2016.02.008⟩
Article dans une revue hal-01812682v1
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PRICKLE1 contributes to cancer cell dissemination through its interaction with mTORC2

Avais M Daulat , François Bertucci , Stéphane Audebert , Arnauld Sergé , Pascal Finetti
Developmental Cell, 2016, 37, pp.311-325. ⟨10.1016/j.devcel.2016.04.011⟩
Article dans une revue hal-01321061v1
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Circulating vascular endothelial growth factor (VEGF) as predictive factor of progression-free survival in patients with advanced chordoma receiving sorafenib: an analysis from a phase II trial of the french sarcoma group (GSF/GETO)

Loic Lebellec , François Bertucci , Emmanuelle Tresch-Bruneel , Emmanuelle Bompas , Yves Toiron
Oncotarget, 2016, Oncotarget, 7 (45), pp.73984-73994. ⟨10.18632/oncotarget.12172⟩
Article dans une revue hal-01453300v1

Safety and efficacy of regorafenib in patients with advanced soft tissue sarcoma (REGOSARC): a randomised, double-blind, placebo-controlled, phase 2 trial

Olivier Mir , Thomas Brodowicz , Antoine Italiano , Jennifer Wallet , Jean-Yves Blay
Lancet Oncology, 2016, 17 (12), pp.1732-1742. ⟨10.1016/s1470-2045(16)30507-1⟩
Article dans une revue hal-03623726v1

Prognostic value of PDL1 expression in pancreatic cancer

David Birnbaum , Pascal Finetti , Alexia Lopresti , Marine Gilabert , Flora Poizat
Oncotarget, 2016, 7 (44), pp.71198-71210. ⟨10.18632/oncotarget.11685⟩
Article dans une revue hal-03583475v1
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Prognostic impact of hormone receptor- and HER2-defined subtypes in inflammatory breast cancer treated with high-dose chemotherapy: a retrospective study

Laurys Boudin , Anthony Gonçalves , Patrick Sfumato , Renaud Sabatier , François Bertucci
American Journal of Cancer, 2016, 7 (14), pp.2077-2084. ⟨10.7150/jca.15797⟩
Article dans une revue inserm-01987531v1

Comparative genomic analysis of primary tumors and metastases in breast cancer

François Bertucci , Pascal Finetti , Arnaud Guille , José Adélaïde , Séverine Garnier
Oncotarget, 2016, 7 (19), pp.27208-27219. ⟨10.18632/oncotarget.8349⟩
Article dans une revue hal-03623731v1

PLZF mutation alters mouse hematopoietic stem cell function and cell cycle progression

Christelle Vincent-Fabert , Nadine Platet , Amelle Vandevelde , Mathilde Poplineau , Myriam Koubi
Blood, 2016, 127 (15), pp.1881-1885. ⟨10.1182/blood-2015-09-666974⟩
Article dans une revue hal-03623736v1
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Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer

Tania M. Puvirajesinghe , François Bertucci , Ashish Jain , Pierluigi Scerbo , Edwige Belotti
Nature Communications, 2016, 7, pp.10318. ⟨10.1038/ncomms10318⟩
Article dans une revue hal-01447570v1

Trabectedin in combination with doxorubicin for first-line treatment of advanced uterine or soft-tissue leiomyosarcoma (LMS-02): a non-randomised, multicentre, phase 2 trial

Patricia Pautier , Anne Floquet , Christine Chevreau , Nicolas Penel , Cécile Guillemet
Lancet Oncology, 2015, 16 (4), pp.457-464. ⟨10.1016/s1470-2045(15)70070-7⟩
Article dans une revue hal-03623745v1

Trabectedin in patients with advanced soft tissue sarcoma: A retrospective national analysis of the French Sarcoma Group

Axel Le Cesne , Isabelle Ray-Coquard , Florence Duffaud , Christine Chevreau , Nicolas Penel
European Journal of Cancer, 2015, 51 (6), pp.742-750. ⟨10.1016/j.ejca.2015.01.006⟩
Article dans une revue hal-03623749v1

PDL1 expression is an independent prognostic factor in localized GIST

François Bertucci , Pascal Finetti , Emilie Mamessier , Maria Abbondanza Pantaleo , Annalisa Astolfi
OncoImmunology, 2015, 4 (5), pp.e1002729. ⟨10.1080/2162402X.2014.1002729⟩
Article dans une revue hal-03583480v1
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H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b

Constance Vennin , Nathalie Spruyt , Fatima Dahmani , Sylvain Julien , François Bertucci
Oncotarget, 2015, 6 (30), ⟨10.18632/oncotarget.4976⟩
Article dans une revue hal-02347866v1

High-grade soft tissue sarcoma arising in a desmoid tumor: case report and review of the literature

François Bertucci , Marjorie Faure , Maria-Rosa Ghigna , Bruno Chetaille , Jérôme Guiramand
Clinical Sarcoma Research, 2015, 5 (1), pp.25. ⟨10.1186/s13569-015-0040-0⟩
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Systems biology analysis of gene expression data and gene network reverse-engineering approaches reveal NFAT5 as a candidate biomarker in Inflammatory Breast Cancer

Andrea Remo , Ines Simeone , Massimo Pancione , Pietro Parcesepe , Pascal Finetti
Journal for Immunotherapy of Cancer, 2015, 3 (Suppl 1), pp.P6. ⟨10.1186/2051-1426-3-s1-p6⟩
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Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease

Maurice P.H.M. Jansen , Leen Sas , Anieta Sieuwerts , Caroline van Cauwenberghe , Diana Ramirez-Ardila
Molecular Oncology, 2015, 9 (6), pp.1218-1233. ⟨10.1016/j.molonc.2015.02.006⟩
Article dans une revue hal-03623744v1
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Simvastatin prevents triple-negative breast cancer metastasis in pre-clinical models through regulation of FOXO3a

Adam Wolfe , Bisrat Debeb , Lara Lacerda , Richard Larson , Arvind Bambhroliya
Breast Cancer Research and Treatment, 2015, 154 (3), pp.495-508. ⟨10.1007/s10549-015-3645-3⟩
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The E2F4 prognostic signature is also predictive of the pathological response of breast cancer to chemotherapy

François Bertucci , Pascal Finetti , Daniel Birnbaum
Breast Cancer Research, 2015, 17 (1), pp.54. ⟨10.1186/s13058-015-0559-2⟩
Article dans une revue hal-03623743v1

Guideline sheets on the side effects of anticancer drugs are useful for general practitioners

Marie-Eve Rouge-Bugat , Donia Lassoued , Joy Bacrie , Nathalie Boussier , Jean-Pierre Delord
Supportive Care in Cancer, 2015, pp.3473 - 3480. ⟨10.1007/s00520-015-2705-x⟩
Article dans une revue hal-01914751v1

Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer

Jennifer Allensworth , Myron Evans , François Bertucci , Amy Aldrich , Richard Festa
Molecular Oncology, 2015, 9 (6), pp.1155-1168. ⟨10.1016/j.molonc.2015.02.007⟩
Article dans une revue hal-03623746v1

Prognostic and predictive value of PDL1 expression in breast cancer

Renaud Sabatier , Pascal Finetti , Emilie Mamessier , José Adelaide , Max Chaffanet
Oncotarget, 2015, 6 (7), pp.5449-5464. ⟨10.18632/oncotarget.3216⟩
Article dans une revue hal-03583484v1
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NGF-induced TrkA/CD44 association is involved in tumor aggressiveness and resistance to lestaurtinib

Léo Aubert , Matthieu Guilbert , Cyril Corbet , Elisabeth Génot , Eric Adriaenssens
Oncotarget, 2015, 6 (12), pp.9807-9819. ⟨10.18632/oncotarget.3227⟩
Article dans une revue hal-03623750v1
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BRCA1 haplotype and clinical benefit of trabectedin in soft-tissue sarcoma patients

A Laroche-Clary , V Chaire , V Le Morvan , A. Neuville , F. Bertucci
British Journal of Cancer, 2015, 112 (4), pp.688-692. ⟨10.1038/bjc.2014.624⟩
Article dans une revue hal-02277467v1
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Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer

Andrea Remo , Ines Simeone , Massimo Pancione , Pietro Parcesepe , Pascal Finetti
Journal of Translational Medicine, 2015, 13 (1), pp.138. ⟨10.1186/s12967-015-0492-2⟩
Article dans une revue inserm-01264508v1

PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy

François Bertucci , Pascal Finetti , Cécile Colpaert , Emilie Mamessier , Maxime Parizel
Oncotarget, 2015, 6 (15), pp.13506-13519. ⟨10.18632/oncotarget.3642⟩
Article dans une revue hal-03583483v1

Interruption versus continuation of trabectedin in patients with soft-tissue sarcoma (T-DIS): a randomised phase 2 trial

Axel Le Cesne , Jean-Yves Blay , Julien Domont , Emmanuelle Tresch-Bruneel , Christine Chevreau
Lancet Oncology, 2015, 16 (3), pp.312-319. ⟨10.1016/s1470-2045(15)70031-8⟩
Article dans une revue hal-03623747v1

Paclitaxel Given Once Per Week With or Without Bevacizumab in Patients With Advanced Angiosarcoma: A Randomized Phase II Trial

Isabelle Ray-Coquard , Julien Domont , Emmanuelle Tresch-Bruneel , Emmanuelle Bompas , Philippe Cassier
Journal of Clinical Oncology, 2015, 33 (25), pp.2797-2802. ⟨10.1200/jco.2015.60.8505⟩
Article dans une revue hal-03623742v1
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Prediction of Early Breast Cancer Metastasis from DNA Microarray Data Using High-Dimensional Cox Regression Models

Christophe Zemmour , Francois Bertucci , Pascal Finetti , Bernard Chetrit , Daniel Birnbaum
Cancer Informatics, 2015, 14(Suppl 2), pp.129-138. ⟨10.4137/cin.s17284⟩
Article dans une revue inserm-01996812v1

The PD1/PDL1 axis, a promising therapeutic target in aggressive breast cancers

François Bertucci , Pascal Finetti , Daniel Birnbaum , Emilie Mamessier
OncoImmunology, 2015, 5 (3), pp.e1085148. ⟨10.1080/2162402X.2015.1085148⟩
Article dans une revue hal-03583477v1
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HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers

Preeti Putcha , Jiyang Yu , Ruth Rodriguez-Barrueco , Laura Saucedo-Cuevas , Patricia Villagrasa
Breast Cancer Research, 2015, 17 (1), pp.149. ⟨10.1186/s13058-015-0658-0⟩
Article dans une revue inserm-01254136v1

EndoPredict predicts for the response to neoadjuvant chemotherapy in ER-positive, HER2-negative breast cancer

François Bertucci , Pascal Finetti , Patrice Viens , Daniel Birnbaum
Cancer Letters, 2014, 355 (1), pp.70-75. ⟨10.1016/j.canlet.2014.09.014⟩
Article dans une revue hal-03623754v1
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Poly(ADP-Ribose) Polymerase 1 (PARP1) Overexpression in Human Breast Cancer Stem Cells and Resistance to Olaparib

Marine Gilabert , Simon Launay , Christophe Ginestier , François Bertucci , Stéphane Audebert
PLoS ONE, 2014, 9 (8), pp.e104302. ⟨10.1371/journal.pone.0104302⟩
Article dans une revue hal-01431935v1
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Primary Synovial Sarcoma of the Thyroid Gland: Case Report and Review of the Literature

Laurys Boudin , Nicolas Fakhry , Bruno Chetaille , Delphine Perrot , Anh Tuan Nguyen
Case Reports in Oncology, 2014, 7 (1), pp.6-13. ⟨10.1159/000357913⟩
Article dans une revue hal-03623760v1

Personalized medicine: Present and future of breast cancer management

Renaud Sabatier , Anthony Gonçalves , François Bertucci
Critical Reviews in Oncology/Hematology, 2014, 91 (3), pp.223-233. ⟨10.1016/j.critrevonc.2014.03.002⟩
Article dans une revue hal-03623758v1
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Candidate Luminal B Breast Cancer Genes Identified by Genome, Gene Expression and DNA Methylation Profiling

Stéphanie Cornen , Arnaud Guille , José Adelaïde , Lynda Addou-Klouche , Pascal Finetti
PLoS ONE, 2014, 9 (1), pp.e81843. ⟨10.1371/journal.pone.0081843⟩
Article dans une revue hal-01614950v1

EFA6B Antagonizes Breast Cancer

Joséphine Zangari , Mariagrazia Partisani , François Bertucci , Julie Milanini , Ghislain Bidaut
Cancer Research, 2014, 74 (19), pp.5493-5506. ⟨10.1158/0008-5472.can-14-0298⟩
Article dans une revue hal-03623755v1

Brief Reports: A Distinct DNA Methylation Signature Defines Breast Cancer Stem Cells and Predicts Cancer Outcome

Rita El Helou , Julien Wicinski , Arnaud Guille , José Adelaïde , Pascal Finetti
STEM CELLS, 2014, 32 (11), pp.3031-3036. ⟨10.1002/stem.1792⟩
Article dans une revue hal-01431934v1

The off-label use of targeted therapies in sarcomas: the OUTC’S program

Lauriane Eberst , Claire Cropet , Axel Le Cesne , Patricia Pautier , Nicolas Penel
BMC Cancer, 2014, 14 (1), pp.870. ⟨10.1186/1471-2407-14-870⟩
Article dans une revue hal-03623753v1

ESPL1 is a candidate oncogene of luminal B breast cancers

Pascal Finetti , Arnaud Guille , José Adelaide , Daniel Birnbaum , Max Chaffanet
Breast Cancer Research and Treatment, 2014, 147 (1), pp.51-59. ⟨10.1007/s10549-014-3070-z⟩
Article dans une revue hal-03623756v1

"Stealth" tumors: Breast cancer cells shun NK-cells anti-tumor immunity

Emilie Mamessier , François Bertucci , Renaud Sabatier , Daniel Birnbaum , Daniel Olive
OncoImmunology, 2014, 1 (3), pp.366-368. ⟨10.4161/onci.18528⟩
Article dans une revue hal-03583489v1

The CINSARC signature: Prognostic and predictive of response to chemotherapy?

François Bertucci , Pascal Finetti , Renaud Sabatier , Daniel Birnbaum
Cell Cycle, 2014, 9 (19), pp.4025-4027. ⟨10.4161/cc.9.19.13463⟩
Article dans une revue hal-03623803v1
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Claudin-low breast cancers: clinical, pathological, molecular and prognostic characterization

Renaud Sabatier , Pascal Finetti , Arnaud Guille , José Adelaïde , Max Chaffanet
Molecular Cancer, 2014, 13, pp.228. ⟨10.2174/156652412798376134⟩
Article dans une revue inserm-01192813v1

Characterization of S628N: a novel KIT mutation found in a metastatic melanoma

Marina Vita , Julie C Tisserand , Isaure Chauvot de Beauchêne , Nicolas Panel , Luba Tchertanov
JAMA Dermatology, 2014, 150 (12), ⟨10.1001/jamadermatol.2014.1437⟩
Article dans une revue hal-01505849v1

Genomic profiling of inflammatory breast cancer: A review

François Bertucci , Pascal Finetti , Peter Vermeulen , Peter van Dam , Luc Dirix
The Breast, 2014, 23 (5), pp.538-545. ⟨10.1016/j.breast.2014.06.008⟩
Article dans une revue hal-03623757v1

Traitements systémiques des cancers du sein inflammatoires : un état des lieux

Audrey Monneur , François Bertucci , Patrice Viens , Anthony Gonçalves
Bulletin du Cancer, 2014, 101 (12), pp.1080-1088. ⟨10.1684/bdc.2014.2014⟩
Article dans une revue hal-03623752v1

Alterations of polycomb gene BMI1 in human myeloproliferative neoplasms

Mandy Brecqueville , José Adélaïde , François Bertucci , Pascal Finetti , Max Chaffanet
Cell Cycle, 2014, 11 (16), pp.3141-3142. ⟨10.4161/cc.21114⟩
Article dans une revue hal-03623775v1

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

Maria Katsogiannou , Claudia Andrieu , Virginie Baylot , Anaïs Baudot , Nelson J Dusetti
Molecular and Cellular Proteomics, 2014, pp.3585-601. ⟨10.1074/mcp.M114.041228⟩
Article dans une revue hal-01104661v1

Uncovering the Molecular Secrets of Inflammatory Breast Cancer Biology: An Integrated Analysis of Three Distinct Affymetrix Gene Expression Datasets

Steven van Laere , Naoto Ueno , Pascal Finetti , Peter Vermeulen , Anthony Lucci
Clinical Cancer Research, 2013, 19 (17), pp.4685-4696. ⟨10.1158/1078-0432.ccr-12-2549⟩
Article dans une revue hal-03623770v1

Cancer du sein triple-négatif : caractéristiques histocliniques et moléculaires, prise en charge et perspectives thérapeutiques

Anthony Gonçalves , Renaud Sabatier , Emmanuelle Charafe-Jauffret , Marine Gilabert , Magali Provansal
Bulletin du Cancer, 2013, 100 (5), pp.453-464. ⟨10.1684/bdc.2013.1740⟩
Article dans une revue hal-03623766v1

Peripheral Blood NK Cells from Breast Cancer Patients Are Tumor-Induced Composite Subsets

Emilie Mamessier , C. Pradel , M.-L. Thibult , C. Drevet , A. Zouine
Journal of Immunology, 2013, 190 (5), pp.2424 - 2436. ⟨10.4049/jimmunol.1200140⟩
Article dans une revue hal-01765648v1

Genomic and expression analysis of microdissected inflammatory breast cancer

Wendy Woodward , Savitri Krishnamurthy , Hideko Yamauchi , Randa El-Zein , Dai Ogura
Breast Cancer Research and Treatment, 2013, 138 (3), pp.761-772. ⟨10.1007/s10549-013-2501-6⟩
Article dans une revue hal-03623767v1

Dramatic and Delayed Response to Doxorubicin-Dacarbazine Chemotherapy of a Giant Desmoid Tumor: Case Report and Literature Review

Audrey Monneur , Bruno Chetaille , Delphine Perrot , Jérôme Guiramand , François Bertucci
Case Reports in Oncology, 2013, 6 (1), pp.127-133. ⟨10.1159/000349918⟩
Article dans une revue hal-03623771v1

Peripheral Blood NK Cells from Breast Cancer Patients Are Tumor-Induced Composite Subsets

E. Mamessier , Lydie Pradel , M.-L. Thibult , C. Drevet , A. Zouine
Journal of Immunology, 2013, 190 (5), pp.2424--2436. ⟨10.4049/jimmunol.1200140⟩
Article dans une revue hal-01612099v1

Comprehensive genome characterization of solitary fibrous tumors using high‐resolution array‐based comparative genomic hybridization

François Bertucci , Corinne Bouvier‐labit , Pascal Finetti , José Adélaïde , Philippe Metellus
Genes, Chromosomes & Cancer, 2013, 52 (2), pp.156-164. ⟨10.1002/gcc.22015⟩
Article dans une revue hal-03623772v1
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Impact of radiotherapy in the management of locally advanced extrahepatic cholangiocarcinoma

Laurence Moureau-Zabotto , Olivier Turrini , Michel Resbeut , Jean-Luc Raoul , Marc Giovannini
BMC Cancer, 2013, 13 (1), pp.568. ⟨10.1186/1471-2407-13-568⟩
Article dans une revue hal-03623761v1
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Gene Expression Profiling of Solitary Fibrous Tumors

François Bertucci , Corinne Bouvier-Labit , Pascal Finetti , Philippe Metellus , José Adelaïde
PLoS ONE, 2013, 8 (5), pp.e64497. ⟨10.1371/journal.pone.0064497⟩
Article dans une revue hal-01537869v1

Comparison of molecular subtype distribution in triple-negative inflammatory and non-inflammatory breast cancers

Hiroko Masuda , Keith Baggerly , Ying Wang , Takayuki Iwamoto , Takae Brewer
Breast Cancer Research, 2013, 15 (6), pp.R112. ⟨10.1186/bcr3579⟩
Article dans une revue hal-03623763v1

Presence of anaplastic lymphoma kinase in inflammatory breast cancer

Fredika Robertson , Emanuel Petricoin Iii , Steven van Laere , François Bertucci , Khoi Chu
SpringerPlus, 2013, 2 (1), pp.497. ⟨10.1186/2193-1801-2-497⟩
Article dans une revue hal-03623764v1

Long-term outcome and effect of maintenance therapy in patients with advanced sarcoma treated with trabectedin: an analysis of 181 patients of the French ATU compassionate use program

Jean-Yves Blay , Antoine Italiano , Isabelle Ray-Coquard , Axel Le Cesne , Florence Duffaud
BMC Cancer, 2013, 13 (1), pp.64. ⟨10.1186/1471-2407-13-64⟩
Article dans une revue hal-03623768v1

Difference in Therapeutic Response Between Basal and Nonbasal Triple-Negative Breast Cancers

François Bertucci , Pascal Finetti , Patrice Viens , Daniel Birnbaum
Oncologist, 2013, 18 (9), pp.1060-1061. ⟨10.1634/theoncologist.2013-0121⟩
Article dans une revue hal-03623765v1

The Histone Deacetylase Inhibitor Abexinostat Induces Cancer Stem Cells Differentiation in Breast Cancer with Low Xist Expression

Marion A. Salvador , Julien Wicinski , Olivier Cabaud , Yves Toiron , Pascal Finetti
Clinical Cancer Research, 2013, 19 (23), pp.6520-6531. ⟨10.1158/1078-0432.CCR-13-0877⟩
Article dans une revue hal-01431936v1

Molecular similarity between myelodysplastic form of chronic myelomonocytic leukemia and refractory anemia with ring sideroblasts

V. Gelsi-Boyer , N. Cervera , François Bertucci , M. Brecqueville , P. Finetti
Haematologica, 2013, 98 (4), pp.576-583. ⟨10.3324/haematol.2012.071506⟩
Article dans une revue hal-03623773v1

Médecine personnalisée et cancer du sein : médecine anticipatoire, évaluation pronostique et ciblage thérapeutique

Anthony Gonçalves , Jessica Moretta , François Eisinger , François Bertucci
Bulletin du Cancer, 2013, 100 (12), pp.1295-1310. ⟨10.1684/bdc.2013.1856⟩
Article dans une revue hal-03623762v1
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ALDH1 is an immunohistochemical diagnostic marker for solitary fibrous tumours and haemangiopericytomas of the meninges emerging from gene profiling study

Corinne Bouvier , François Bertucci , Philippe Métellus , Pascal Finetti , André Maues de Paula
Acta Neuropathologica Communications, 2013, 1 (1), pp.10
Article dans une revue inserm-00837790v1

ALDH1-Positive Cancer Stem Cells Predict Engraftment of Primary Breast Tumors and Are Governed by a Common Stem Cell Program

Emmanuelle Charafe-Jauffret , Christophe Ginestier , François Bertucci , Olivier Cabaud , Julien Wicinski
Cancer Research, 2013, 73 (24), pp.7290-7300. ⟨10.1158/0008-5472.CAN-12-4704⟩
Article dans une revue hal-01431937v1

Chimiothérapie ciblée du cancer du sein basée sur une analyse génomique de la tumeur

Isabelle Pellegrini , Myrto Rapti , Jean-Marc Extra , Anouk Petri-Cal , Themis Apostolidis
Médecine/Sciences, 2012, 28, pp.24-27. ⟨10.1051/medsci/2012281s107⟩
Article dans une revue hal-03623782v1

Breast Metastasis of a Squamous Cell Carcinoma of the Uterine Cervix Mimicking Inflammatory Breast Cancer

Renaud Sabatier , Céline Roussin , Jean-Pierre Riviere , Aurélie Jalaguier , Jocelyne Jacquemier
Case Reports in Oncology, 2012, 5 (2), pp.464-470. ⟨10.1159/000342255⟩
Article dans une revue hal-03623778v1

Génomique et recherche clinique en cancérologie mammaire

François Bertucci , Daniel Birnbaum
Médecine/Sciences, 2012, 28, pp.14-18. ⟨10.1051/medsci/2012281s105⟩
Article dans une revue hal-03623780v1
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Outcome of Patients with Platelet-Derived Growth Factor Receptor Alpha–Mutated Gastrointestinal Stromal Tumors in the Tyrosine Kinase Inhibitor Era

Philippe Cassier , Elena Fumagalli , Piotr Rutkowski , Patrick Schöffski , Martine van Glabbeke
Clinical Cancer Research, 2012, 18 (16), pp.4458-4464. ⟨10.1158/1078-0432.ccr-11-3025⟩
Article dans une revue hal-03623776v1
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Interactome-Transcriptome integration for predicting distant metastasis in breast cancer

Maxime Garcia , Raphaelle Millat-Carus , François Bertucci , Pascal Finetti , Daniel Birnbaum
Bioinformatics, 2012, 28 (5), pp.672-678. ⟨10.1093/bioinformatics/bts025⟩
Article dans une revue hal-01784470v1

8q24 Cancer Risk Allele Associated with Major Metastatic Risk in Inflammatory Breast Cancer

François Bertucci , Arnaud Lagarde , Anthony Ferrari , Pascal Finetti , Emmanuelle Charafe-Jauffret
PLoS ONE, 2012, 7 (5), pp.e37943. ⟨10.1371/journal.pone.0037943⟩
Article dans une revue hal-03623777v1

Mevalonate Metabolism Regulates Basal Breast Cancer Stem Cells and Is a Potential Therapeutic Target

Christophe Ginestier , Florence Monville , Julien Wicinski , Olivier Cabaud , Nathalie Cervera
STEM CELLS, 2012, 30 (7), pp.1327-1337. ⟨10.1002/stem.1122⟩
Article dans une revue hal-01431941v1

High expression of indoleamine 2,3-dioxygenase in the tumour is associated with medullary features and favourable outcome in basal-like breast carcinoma

Jocelyne Jacquemier , François Bertucci , Pascal Finetti , Benjamin Esterni , Emmanuelle Charafe-Jauffret
International Journal of Cancer, 2012, 130 (1), pp.96-104. ⟨10.1002/ijc.25979⟩
Article dans une revue hal-03623783v1

Pancreatic metastasis from osteosarcoma and Ewing sarcoma: literature review

François Bertucci , Julia Araujo , Marc Giovannini
Scandinavian Journal of Gastroenterology, 2012, 48 (1), pp.4-8. ⟨10.3109/00365521.2012.711852⟩
Article dans une revue hal-03623774v1

Solitary Fibrous Tumor in the Round Ligament of the Liver: A Fortunate Intraoperative Discovery

Laura Beyer , Jean-Robert Delpero , Bruno Chetaille , Anthony Sarran , Delphine Perrot
Case Reports in Oncology, 2012, 5 (1), pp.187-194. ⟨10.1159/000338616⟩
Article dans une revue hal-03623784v1

Comparison of doxorubicin and weekly paclitaxel efficacy in metastatic angiosarcomas

Antoine Italiano , Angela Cioffi , Nicolas Penel , Matteo Giaj Levra , Corinne Delcambre
Cancer, 2012, 118 (13), pp.3330-3336. ⟨10.1002/cncr.26599⟩
Article dans une revue hal-03623788v1
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A refined molecular taxonomy of breast cancer.

Michael Guedj , Laëtitia Marisa , Aurélien de Reynies , Béatrice Orsetti , Renaud Schiappa
Oncogene, 2012, 31 (9), pp.1196-206. ⟨10.1038/onc.2011.301⟩
Article dans une revue inserm-00611752v1

Tests diagnostiques et thérapies ciblées en cancérologie

Patricia Marino , François Bertucci , Anthony Gonçalves , Valérie Seror
Médecine/Sciences, 2012, 28, pp.19-23. ⟨10.1051/medsci/2012281s106⟩
Article dans une revue hal-03623781v1

Serum creatine kinase increase in patients treated with tyrosine kinase inhibitors for solid tumors.

Antoine Adenis , Olivier Bouché , François Bertucci , Elsa Kalbacher , Charles Fournier
Medical oncology and tumor pharmacotherapy, 2012, 29 (4), pp.3003-8. ⟨10.1007/s12032-012-0204-1⟩
Article dans une revue hal-00850693v1

Gene expression profiling identifies sST2 as an effector of ErbB2-driven breast carcinoma cell motility, associated with metastasis.

J. Gillibert-Duplantier , B. Duthey , V. Sisirak , D. Salaün , T. Gargi
Oncogene, 2012, 31 (30), pp.3516-24. ⟨10.1038/onc.2011.525⟩
Article dans une revue hal-00820060v1

Solitary Fibrous Tumor of the Prostate: Case Report and Review of the Literature

Laurence Moureau-Zabotto , Bruno Chetaille , Franck Bladou , Pierre-Yves Dauvergne , Myriam Marcy
Case Reports in Oncology, 2012, 5 (1), pp.22-29. ⟨10.1159/000335680⟩
Article dans une revue hal-03623785v1

Gene expression profiling of breast tumor cell lines to predict for therapeutic response to microtubule-stabilizing agents

Gais Kadra , Pascal Finetti , Yves Toiron , Patrice Viens , Daniel Birnbaum
Breast Cancer Research and Treatment, 2012, 132 (3), pp.1035-1047. ⟨10.1007/s10549-011-1687-8⟩
Article dans une revue hal-03623793v1

Mutation analysis of ASXL1, CBL, DNMT3A, IDH1, IDH2, JAK2, MPL, NF1, SF3B1, SUZ12, and TET2 in myeloproliferative neoplasms

Mandy Brecqueville , Jérôme Rey , François Bertucci , Emilie Coppin , Pascal Finetti
Genes, Chromosomes & Cancer, 2012, 51 (8), pp.743-755. ⟨10.1002/gcc.21960⟩
Article dans une revue hal-03623779v1

Contrasted outcomes to gefitinib on tumoral IGF1R expression in head and neck cancer patients receiving postoperative chemoradiation (GORTEC trial 2004-02).

Juliette Thariat , René-Jean Bensadoun , Marie-Christine Etienne-Grimaldi , Dominique Grall , Frédérique Penault-Llorca
Clinical Cancer Research, 2012, 18 (18), pp.5123-33. ⟨10.1158/1078-0432.CCR-12-1518⟩
Article dans une revue hal-00770510v1
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Are there candidates for high-dose chemotherapy in ovarian carcinoma?

Renaud Sabatier , Anthony Gonçalves , François Bertucci , Maria-Antonietta Capiello , Frédérique Rousseau
Journal of Experimental and Clinical Cancer Research, 2012, 31 (1), pp.87. ⟨10.1186/1756-9966-31-87⟩
Article dans une revue inserm-00765646v1

Endometriosis-Associated Ovarian Carcinomas

François Bertucci
New England Journal of Medicine, 2011, 364 (5), pp.482-485. ⟨10.1056/nejmc1012780⟩
Article dans une revue hal-03623797v1

Down-Regulation of ECRG4, a Candidate Tumor Suppressor Gene, in Human Breast Cancer

Renaud Sabatier , Pascal Finetti , José Adelaide , Arnaud Guille , Jean-Paul Borg
PLoS ONE, 2011, 6 (11), pp.e27656. ⟨10.1371/journal.pone.0027656⟩
Article dans une revue hal-03623789v1
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Kinome expression profiling and prognosis of basal breast cancers.

Renaud Sabatier , Pascal Finetti , Emilie Mamessier , Stéphane Raynaud , Nathalie Cervera
Molecular Cancer, 2011, 10 (1), pp.86. ⟨10.1186/1476-4598-10-86⟩
Article dans une revue inserm-00614833v1

High incidence of asymptomatic renal cancer in late survivors after heart transplantation

Pierre Ambrosi , François Bertucci , Bernard Kreitmann
The Journal of Heart and Lung Transplantation, 2011, 30 (10), pp.1202-1203. ⟨10.1016/j.healun.2011.05.003⟩
Article dans une revue hal-03623795v1

Neoadjuvant imatinib in patients with locally advanced non metastatic GIST in the prospective BFR14 trial.

Aurore Blesius , Philippe A Cassier , François Bertucci , Jérome Fayette , Isabelle Ray-Coquard
BMC Cancer, 2011, 11, pp.72. ⟨10.1186/1471-2407-11-72⟩
Article dans une revue hal-00779604v1

Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

Emilie Mamessier , Aude Sylvain , Marie-Laure Thibult , Gilles Houvenaeghel , Jocelyne Jacquemier
Journal of Clinical Investigation, 2011, 121 (9), pp.3609 - 3622. ⟨10.1172/JCI45816⟩
Article dans une revue hal-01765654v1

Human Breast Tumor Cells Induce Self-Tolerance Mechanisms to Avoid NKG2D-Mediated and DNAM-Mediated NK Cell Recognition

Emilie Mamessier , A. Sylvain , F. Bertucci , R. Castellano , P. Finetti
Cancer Research, 2011, 71 (21), pp.6621 - 6632. ⟨10.1158/0008-5472.CAN-11-0792⟩
Article dans une revue hal-01765652v1

High-Resolution Comparative Genomic Hybridization of Inflammatory Breast Cancer and Identification of Candidate Genes

Ismahane Bekhouche , Pascal Finetti , José Adelaïde , Anthony Ferrari , Carole Tarpin
PLoS ONE, 2011, 6 (2), pp.e16950. ⟨10.1371/journal.pone.0016950⟩
Article dans une revue hal-03623798v1
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Efficacy of epidermal growth factor receptor targeting in advanced chordoma: case report and literature review

Simon Launay , Bruno Chetaille , Fanny Medina , Delphine Perrot , Serge Nazarian
BMC Cancer, 2011, 11 (1), pp.423. ⟨10.1186/1471-2407-11-423⟩
Article dans une revue hal-03623791v1
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Primary leiomyosarcoma of the seminal vesicle: Case report and review of the literature

Cécile Cauvin , Laurence Moureau-Zabotto , Bruno Chetaille , Werner Hilgers , Yves Denoux
BMC Cancer, 2011, 11 (1), pp.323. ⟨10.1186/1471-2407-11-323⟩
Article dans une revue hal-03623794v1

CD47–signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction

Xi Wen Zhao , Ellen van Beek , Karin Schornagel , Hans van Der Maaden , Michel van Houdt
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (45), pp.18342-18347. ⟨10.1073/pnas.1106550108⟩
Article dans une revue hal-03623790v1

ZNF703 gene amplification at 8p12 specifies luminal B breast cancer

Fabrice Sircoulomb , Nathalie Nicolas , Anthony Ferrari , Pascal Finetti , Ismahane Bekhouche
EMBO Molecular Medicine, 2011, 3 (3), pp.153-166. ⟨10.1002/emmm.201100121⟩
Article dans une revue hal-01431945v1

Clinical Application of Proteomics in Breast Cancer: State of the Art and Perspectives

Anthony Goncalves , François Bertucci
Medical Principles and Practice, 2011, 20 (1), pp.4-18. ⟨10.1159/000319544⟩
Article dans une revue hal-03623800v1

Planification systématique de l'apprentissage hospitalier de la cancérologie par les étudiants en DCEM

Anthony Gonçalves , Patrice Viens , Marine Gilabert , Olivier Turrini , Éric Lambaudie
Bulletin du Cancer, 2011, 98 (12), pp.1489-1508. ⟨10.1684/bdc.2011.1504⟩
Article dans une revue hal-03623787v1

Peritumoural vascular invasion: A major determinant of triple-negative breast cancer outcome

Renaud Sabatier , Jocelyne Jacquemier , François Bertucci , Benjamin Esterni , Pascal Finetti
European Journal of Cancer, 2011, 47 (10), pp.1537-1545. ⟨10.1016/j.ejca.2011.02.002⟩
Article dans une revue hal-03623796v1
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Protein expression, survival and docetaxel benefit in node-positive breast cancer treated with adjuvant chemotherapy in the FNCLCC - PACS 01 randomized trial.

Jocelyne Jacquemier , Jean-Marie Boher , Henri Roche , Benjamin Esterni , Daniel Serin
Breast Cancer Research, 2011, 13 (6), pp.R109. ⟨10.1186/bcr3051⟩
Article dans une revue inserm-00647247v1
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Kinome expression profiling and prognosis of basal breast cancers

Renaud Sabatier , Pascal Finetti , Emilie Mamessier , Stéphane Raynaud , Nathalie Cervera
Molecular Cancer, 2011, 10 (1), pp.86. ⟨10.1186/1476-4598-10-86⟩
Article dans une revue hal-03606422v1

Gene Expression Profiling for In Silico Microdissection of Hodgkin's Lymphoma Microenvironment and Identification of Prognostic Features

François Bertucci , Bruno Chetaille , Luc Xerri
Advances in Hematology, 2011, 2011, pp.1-8. ⟨10.1155/2011/485310⟩
Article dans une revue hal-03623801v1
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Characterisation of Genome-Wide PLZF/RARA Target Genes

Salvatore Spicuglia , Christelle Vincent-Fabert , Touati Benoukraf , Guillaume Tibéri , Andrew J Saurin
PLoS ONE, 2011, 6 (9), pp.e24176. ⟨10.1371/journal.pone.0024176⟩
Article dans une revue hal-00674513v1

Systemic therapy of inflammatory breast cancer from high-dose chemotherapy to targeted therapies

Patrice Viens , Carole Tarpin , Henri Roche , François Bertucci
Cancer, 2010, 116 (S11), pp.2829-2836. ⟨10.1002/cncr.25168⟩
Article dans une revue hal-03623807v1
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A gene expression signature identifies two prognostic subgroups of basal breast cancer

Renaud Sabatier , Pascal Finetti , Nathalie Cervera , Eric Lambaudie , Benjamin Esterni
Breast Cancer Research and Treatment, 2010, 126 (2), pp.407-420. ⟨10.1007/s10549-010-0897-9⟩
Article dans une revue hal-00583558v1

Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer

Emmanuelle Charafe-Jauffret , Christophe Ginestier , Flora Iovino , Carole Tarpin , Mark Diebel
Clinical Cancer Research, 2010, 16 (1), pp.45-55. ⟨10.1158/1078-0432.CCR-09-1630⟩
Article dans une revue hal-01431949v1
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Gene expression profile predicts outcome after anthracycline-based adjuvant chemotherapy in early breast cancer

François Bertucci , Nathalie Borie , Henri Roche , Thomas Bachelot , Jean-Marc Doussal
Breast Cancer Research and Treatment, 2010, 127 (2), pp.363-373. ⟨10.1007/s10549-010-1003-z⟩
Article dans une revue hal-00594464v1
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-- mRNA expression in human breast cancer: a meta-analysis

Anthony Gonçalves , Pascal Finetti , Renaud Sabatier , Marine Gilabert , José Adelaïde
Breast Cancer Research and Treatment, 2010, 127 (1), pp.273-281. ⟨10.1007/s10549-010-1199-y⟩
Article dans une revue hal-00594471v1

Gene expression profiling of inflammatory breast cancer

François Bertucci , Pascal Finetti , Daniel Birnbaum , Patrice Viens
Cancer, 2010, 116 (S11), pp.2783-2793. ⟨10.1002/cncr.25165⟩
Article dans une revue hal-03623806v1

Loss, mutation and deregulation of L3MBTL4 in breast cancers

Lynda Addou-Klouche , José Adélaïde , Pascal Finetti , Nathalie Cervera , Anthony Ferrari
Molecular Cancer, 2010, 9 (1), pp.213. ⟨10.1186/1476-4598-9-213⟩
Article dans une revue hal-03623805v1

Protéomique et cancer du sein : à la recherche de nouveaux biomarqueurs diagnostiques et théragnostiques

Marine Gilabert , Stéphane Audebert , Patrice Viens , Jean-Paul Borg , François Bertucci
Bulletin du Cancer, 2010, 97 (3), pp.321-339. ⟨10.1684/bdc.2010.1061⟩
Article dans une revue hal-03623810v1

BARD1 homozygous deletion, a possible alternative to BRCA1 mutation in basal breast cancer

Renaud Sabatier , José Adélaïde , Pascal Finetti , Anthony Ferrari , Laetitia Huiart
Genes, Chromosomes & Cancer, 2010, 49 (12), pp.1143-1151. ⟨10.1002/gcc.20822⟩
Article dans une revue hal-03623799v1

Genome profiling of ERBB2-amplified breast cancers

Fabrice Sircoulomb , Ismahane Bekhouche , Pascal Finetti , José Adélaïde , Azza Ben Hamida
BMC Cancer, 2010, 10 (1), pp.539. ⟨10.1186/1471-2407-10-539⟩
Article dans une revue hal-03623802v1
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Economic issues involved in integrating genomic testing into clinical care: the case of genomic testing to guide decision-making about chemotherapy for breast cancer patients

Patricia Marino , Carole Siani , François Bertucci , Henri Roche , Anne-Laure Martin
Breast Cancer Research and Treatment, 2010, 129 (2), pp.401-409. ⟨10.1007/s10549-010-1242-z⟩
Article dans une revue hal-00615386v1
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Low-grade extraskeletal osteosarcoma of the chest wall: case report and review of literature.

Renaud Sabatier , Corinne Bouvier , Gonzague de Pinieux , Anthony Sarran , Isabelle Brenot-Rossi
BMC Cancer, 2010, 10, pp.645. ⟨10.1186/1471-2407-10-645⟩
Article dans une revue hal-00546735v1

Pediatric mastocytosis–associated KIT extracellular domain mutations exhibit different functional and signaling properties compared with KIT-phosphotransferase domain mutations

Ying Yang , Sébastien Létard , Laurence Borge , Amandine Chaix , Katia Hanssens
Blood, 2010, 116 (7), pp.1114-1123. ⟨10.1182/blood-2009-06-226027⟩
Article dans une revue hal-03623808v1

Une forme « ariditaire » du cancer de l’ovaire

David Birnbaum , Renaud Sabatier , Emilie Mamessier , Daniel Birnbaum , François Bertucci
Médecine/Sciences, 2010, 26 (12), pp.1040-1042. ⟨10.1051/medsci/201026121040⟩
Article dans une revue hal-03583491v1

Meningeal chondroblastic osteosarcoma: case report and review of the literature

Emilie Romeo , Olivier Gisserot , Jean-Pierre de Jaureguiberry , Nicolas Desse , Jean-Baptiste Souraud
Journal of Neuro-Oncology, 2010, 100 (2), pp.305-309. ⟨10.1007/s11060-010-0167-z⟩
Article dans une revue hal-03623809v1
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Masitinib combined with standard Gemcitabine chemotherapy : in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model

M. Humbert , N. Casteran , S. Letard , K. Hanssens , J. Iovanna
PLoS ONE, 2010, 5 (3), pp.e9430-e9437. ⟨10.1371/journal.pone.0009430⟩
Article dans une revue hal-00473110v1

Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: an open-label multicentre randomised phase 3 trial

Axel Le Cesne , Isabelle Ray-Coquard , Binh Nguyen Bui , Antoine Adenis , Maria Rios
Lancet Oncology, 2010, 11 (10), pp.942-949. ⟨10.1016/s1470-2045(10)70222-9⟩
Article dans une revue hal-03623804v1

A gene expression signature of primary resistance to imatinib in chronic myeloid leukemia

Hugues de Lavallade , Pascal Finetti , Nadine Carbuccia , Jamshid Khorashad , Aude Charbonnier
Leukemia Research, 2010, 34 (2), pp.254-257. ⟨10.1016/j.leukres.2009.09.026⟩
Article dans une revue hal-03623812v1

CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines

Gwladys Zabouo , Anne-Marie Imbert , Jocelyne Jacquemier , Pascal Finetti , Thomas Moreau
Breast Cancer Research, 2009, 11 (1), pp.R1. ⟨10.1186/bcr2215⟩
Article dans une revue hal-03623818v1

Retinoid signaling regulates breast cancer stem cell differentiation

Christophe Ginestier , Julien Wicinski , Nathalie Cervera , Florence Monville , Pascal Finetti
Cell Cycle, 2009, 8 (20), pp.3297-3302. ⟨10.4161/cc.8.20.9761⟩
Article dans une revue hal-01431955v1

How different are luminal A and basal breast cancers?

François Bertucci , Pascal Finetti , Nathalie Cervera , Emmanuelle Charafe-Jauffret , Max Buttarelli
International Journal of Cancer, 2009, 124 (6), pp.1338-1348. ⟨10.1002/ijc.24055⟩
Article dans une revue hal-03623816v1

Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer

Jocelyne Jacquemier , Emmanuelle Charafe-Jauffret , Florence Monville , Benjamin Esterni , Jean Marc Extra
Breast Cancer Research, 2009, 11 (2), pp.R23. ⟨10.1186/bcr2249⟩
Article dans une revue hal-03623814v1

Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome

Bruno Chetaille , François Bertucci , Pascal Finetti , Benjamin Esterni , Aspasia Stamatoullas
Blood, 2009, 113 (12), pp.2765-3775. ⟨10.1182/blood-2008-07-168096⟩
Article dans une revue hal-03623820v1

Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

Emmanuelle Charafe-Jauffret , Christophe Ginestier , Flora Iovino , Julien Wicinski , Nathalie Cervera
Cancer Research, 2009, 69 (4), pp.1302-1313. ⟨10.1158/0008-5472.CAN-08-2741⟩
Article dans une revue hal-01431954v1

Docetaxel first-line therapy in HER2-negative advanced breast cancer: a cohort study in patients with prospectively determined HER2 status

Anthony Gonçalves , Mathilde Deblock , Benjamin Esterni , Carole Tarpin , François Bertucci
Anti-Cancer Drugs, 2009, 20 (10), pp.946-952. ⟨10.1097/cad.0b013e328331178f⟩
Article dans une revue hal-03623811v1

Gene Expression Profiles as Predictors of Poor Outcomes in Stage II Colorectal Cancer: A Systematic Review and Meta-analysis

An-Ting Lu , Shelley Salpeter , Anthony Reeve , Steven Eschrich , Patrick Johnston
Clinical Colorectal Cancer, 2009, 8 (4), pp.207-214. ⟨10.3816/ccc.2009.n.035⟩
Article dans une revue hal-03623813v1

Gene expression profiling and prediction of clinical outcome in ovarian cancer

Renaud Sabatier , Pascal Finetti , Nathalie Cervera , Daniel Birnbaum , François Bertucci
Critical Reviews in Oncology/Hematology, 2009, 72 (2), pp.98-109. ⟨10.1016/j.critrevonc.2009.01.007⟩
Article dans une revue hal-03623817v1

Distant metastasis: not out of reach any more

François Bertucci , Daniel Birnbaum
Journal of Biology, 2009, 8 (3), pp.28. ⟨10.1186/jbiol128⟩
Article dans une revue hal-03623815v1

Sixteen–Kinase Gene Expression Identifies Luminal Breast Cancers with Poor Prognosis

Pascal Finetti , Nathalie Cervera , Emmanuelle Charafe-Jauffret , Christian Chabannon , Colette Charpin
Cancer Research, 2008, 68 (3), pp.767-776. ⟨10.1158/0008-5472.can-07-5516⟩
Article dans une revue hal-03623826v1

Classification pronostique du cancer du sein et profils d’expression génique sur puces à ADN

François Bertucci , Pascal Finetti , Nathalie Cervera , Daniel Birnbaum
Médecine/Sciences, 2008, 24 (6-7), pp.599-606. ⟨10.1051/medsci/20082467599⟩
Article dans une revue hal-03623822v1

Markers of subtypes in inflammatory breast cancer studied by immunohistochemistry: Prominent expression of P-cadherin

Azza Ben Hamida , Intidhar Labidi , Karima Mrad , Emmanuelle Charafe-Jauffret , Saïda Ben Arab
BMC Cancer, 2008, 8 (1), pp.28. ⟨10.1186/1471-2407-8-28⟩
Article dans une revue hal-03623827v1

Protein Profiling of Human Breast Tumor Cells Identifies Novel Biomarkers Associated with Molecular Subtypes

Anthony Goncçalves , Emmanuelle Charafe-Jauffret , François Bertucci , Stéphane Audebert , Yves Toiron
Molecular and Cellular Proteomics, 2008, 7 (8), pp.1420-1433. ⟨10.1074/mcp.m700487-mcp200⟩
Article dans une revue hal-03623824v1

Stem cells and epithelial cancers: the example of breast cancer

Emanuelle Charafe-Jauffret , Christophe Ginestier , Florence Monville , Julien Wicinski , François Bertucci
Annales de Pathologie, 2008, 28, pp.S30-S32. ⟨10.1016/j.annpat.2008.09.005⟩
Article dans une revue hal-01431960v1
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Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles.

François Bertucci , Béatrice Orsetti , Vincent Nègre , Pascal Finetti , Carole Rougé
Oncogene, 2008, 27 (40), pp.5359-72. ⟨10.1038/onc.2008.158⟩
Article dans une revue inserm-00290484v1

Absence of ESR1 amplification in a series of breast cancers

José Adélaïde , Pascal Finetti , Emmanuelle Charafe-Jauffret , Julien Wicinski , Jocelyne Jacquemier
International Journal of Cancer, 2008, 123 (12), pp.2970-2972. ⟨10.1002/ijc.23786⟩
Article dans une revue hal-03623819v1

Clinical proteomics and breast cancer: strategies for diagnostic and therapeutic biomarker discovery

François Bertucci , Anthony Goncalves
Future Oncology, 2008, 4 (2), pp.271-287. ⟨10.2217/14796694.4.2.271⟩
Article dans une revue hal-03623823v1

Reasons for breast cancer heterogeneity

François Bertucci , Daniel Birnbaum
Journal of Biology, 2008, 7 (2), pp.6. ⟨10.1186/jbiol67⟩
Article dans une revue hal-03623828v1

How basal are triple-negative breast cancers?

F. Bertucci , Pascal Finetti , Nathalie Cervera , Benjamin Esterni , Fabienne Hermitte
International Journal of Cancer, 2008, 123 (1), pp.236-240. ⟨10.1002/ijc.23518⟩
Article dans une revue hal-03623624v1

A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment

Anthony Gonçalves , Séverine Esteyries , Brynn Taylor-Smedra , Arnaud Lagarde , Mounay Ayadi
BMC Cancer, 2008, 8 (1), pp.169. ⟨10.1186/1471-2407-8-169⟩
Article dans une revue hal-03623821v1

Defining the Molecular Biology of Inflammatory Breast Cancer

Emmanuelle Charafe-Jauffret , Carole Tarpin , Patrice Viens , François Bertucci
Seminars in Oncology, 2008, 35 (1), pp.41-50. ⟨10.1053/j.seminoncol.2007.11.015⟩
Article dans une revue hal-03623825v1

ERBB2 phosphorylation and trastuzumab sensitivity of breast cancer cell lines

C. Ginestier , J. Adelaiede , A. Goncalves , L. Repellini , F. Sircoulomb
Oncogene, 2007, 26 (50), pp.7163-7169. ⟨10.1038/sj.onc.1210528⟩
Article dans une revue hal-01431967v1

Moesin expression is a marker of basal breast carcinomas

Emmanuelle Charafe-Jauffret , Florence Monville , Francois Bertucci' , Benjamin Esterni , Christophe Ginestier
International Journal of Cancer, 2007, 121 (8), pp.1779-1785. ⟨10.1002/ijc.22923⟩
Article dans une revue hal-01431969v1

Towards an integrated cellular and molecular: definition of breast cancers

Emmanuelle Charafe-Jauffret , Max Chaffanet , François Bertucci , Christophe Ginestier , Jocelyne Jacquemier
Médecine/Sciences, 2007, 23 (6-7), pp.626-632. ⟨10.1051/medsci/20072367626⟩
Article dans une revue hal-01431964v1

A Gene Signature in Breast Cancer

François Bertucci
New England Journal of Medicine, 2007, 356 (18), pp.1887-1888. ⟨10.1056/nejmc070393⟩
Article dans une revue hal-03623833v1

Breast cancer genomics: real-time use

François Bertucci , Daniel Birnbaum
Lancet Oncology, 2007, 8 (12), pp.1045-1047. ⟨10.1016/s1470-2045(07)70350-9⟩
Article dans une revue hal-03623829v1

Desmoid-Type Fibromatosis

François Bertucci , Anthony Gonçalves , Patrice Viens , Genevieve Monges , Patrice Dubreuil
Journal of Neurosurgery, 2007, 107 (2), pp.473-475. ⟨10.3171/jns-07/08/0473⟩
Article dans une revue hal-03623832v1

Lung cancer in elderly patients: A retrospective analysis of practice in a single institution

Anne Madroszyk-Flandin , Sophie Bagattini , Anthony Gonçalves , Naji Salem , Frédéric Viret
Critical Reviews in Oncology/Hematology, 2007, 64 (1), pp.43-48. ⟨10.1016/j.critrevonc.2007.06.009⟩
Article dans une revue hal-03623831v1

Integrated Profiling of Basal and Luminal Breast Cancers

J. Adelaide , P. Finetti , I. Bekhouche , L. Repellini , J. Geneix
Cancer Research, 2007, 67 (24), pp.11565-11575. ⟨10.1158/0008-5472.can-07-2536⟩
Article dans une revue hal-03623830v1

Response of a KIT-Positive Extra-Abdominal Fibromatosis to Imatinib Mesylate and KIT Genetic Analysis

Anthony Gonçalves , Genevieve Monges , Ying Yang , Fabienne Palmerini , Patrice Dubreuil
JNCI: Journal of the National Cancer Institute, 2006, 98 (8), pp.562-563. ⟨10.1093/jnci/djj137⟩
Article dans une revue hal-03623835v1
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FGFR1 and WT1 are markers of human prostate cancer progression.

Elizabeth Devilard , Franck Bladou , Olivier Ramuz , Gilles Karsenty , Jean-Philippe Dalès
BMC Cancer, 2006, 6, pp.272. ⟨10.1186/1471-2407-6-272⟩
Article dans une revue inserm-00121110v1

Comparison of Induced Sputum and Bronchoalveolar Lavage in Lung Transplant Recipients

François Bertucci , Pascal Finetti , Nathalie Cervera , Emmanuelle Charafe-Jauffret , José Adélaïde
The Journal of Heart and Lung Transplantation, 2006, 25 (5), pp.523-532. ⟨10.1016/j.healun.2005.12.009⟩
Article dans une revue hal-03583497v1

Identification des facteurs génétiques associés à l'évolution des cancers coliques

Sylviane Olschwang , Frédéric Viret , Geneviève Monges , Jean-François Seitz , Nicolas Sevenet
Médecine/Sciences, 2006, 22, pp.45-49. ⟨10.1051/medsci/2006221s45⟩
Article dans une revue hal-03623837v1

Gene Expression Profiling and Clinical Outcome in Breast Cancer

François Bertucci , Pascal Finetti , Nathalie Cervera , Dominique Maraninchi , Patrice Viens
OMICS, 2006, 10 (4), pp.429-443. ⟨10.1089/omi.2006.10.429⟩
Article dans une revue hal-03623836v1

Gene Expression Profiling Shows Medullary Breast Cancer Is a Subgroup of Basal Breast Cancers

François Bertucci , Pascal Finetti , Nathalie Cervera , Emmanuelle Charafe-Jauffret , Emilie Mamessier
Cancer Research, 2006, 66 (9), pp.4636-4644. ⟨10.1158/0008-5472.CAN-06-0031⟩
Article dans une revue hal-03606415v1

Gene expression profiling of breast cell lines identifies potential new basal markers

E Charafe-Jauffret , C Ginestier , F Monville , P Finetti , José Adelaïde
Oncogene, 2006, 25 (15), pp.2273-2284. ⟨10.1038/sj.onc.1209254⟩
Article dans une revue hal-01431970v1

Prognosis and gene expression profiling of 20q13-amplified breast cancers

Christophe Ginestier , Nathalie Cervera , Pascal Finetti , Sverine Esteyries , Benjamin Esterni
Clinical Cancer Research, 2006, 12 (15), pp.4533-4544. ⟨10.1158/1078-0432.CCR-05-2339⟩
Article dans une revue hal-01431971v1

Proteomics of Breast Cancer

François Bertucci , Daniel Birnbaum , Anthony Goncalves
Molecular and Cellular Proteomics, 2006, 5 (10), pp.1772-1786. ⟨10.1074/mcp.r600011-mcp200⟩
Article dans une revue hal-03623834v1

Gene expression profiling identifies molecular subgroups among nodal peripheral T-cell lymphomas

B Ballester , O Ramuz , C Gisselbrecht , G Doucet , L Loi
Oncogene, 2006, 25 (10), pp.1560-1570. ⟨10.1038/sj.onc.1209178⟩
Article dans une revue hal-01612147v1

Gene Expression Profiling Identifies Molecular Subtypes of Inflammatory Breast Cancer

François Bertucci , Pascal Finetti , Jacques Rougemont , Emmanuelle Charafe-Jauffret , Nathalie Cervera
Cancer Research, 2005, 65 (6), pp.2170-2178. ⟨10.1158/0008-5472.can-04-4115⟩
Article dans une revue hal-03623838v1
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Comprehensive profiling of 8p11-12 amplification in breast cancer.

Véronique Gelsi-Boyer , Béatrice Orsetti , Nathalie Cervera , Pascal Finetti , Fabrice Sircoulomb
Molecular Cancer Research, 2005, 3 (12), pp.655-67. ⟨10.1158/1541-7786.MCR-05-0128⟩
Article dans une revue inserm-00158812v1

Immunophenotypic analysis of inflammatory breast cancers: identification of an‘inflammatory signature’

Emmanuelle Charafe-Jauffret , Carole Tarpin , Valérie-Jeanne Bardou , François Bertucci , Christophe Ginestier
Journal of Pathology, 2004, 202 (3), pp.265-273. ⟨10.1002/path.1515⟩
Article dans une revue hal-03623843v1
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Feature extraction and signal processing for nylon DNA microarrays.

Fabrice Lopez , Jacques Rougemont , Béatrice Loriod , Aude Bourgeois , Laurence Loï
BMC Genomics, 2004, 5 (1), pp.38. ⟨10.1186/1471-2164-5-38⟩
Article dans une revue inserm-00112016v1
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Gene expression profiling for molecular characterization of inflammatory breast cancer and prediction of response to chemotherapy

F Bertucci , P Finetti , J Rougemont , E Charafe-Jauffret , V Nasser
Cancer Research, 2004, 64 (23), pp.8558-8565. ⟨10.1158/0008-5472.CAN-04-2696⟩
Article dans une revue hal-01612154v1

Gene expression profiling of thyroid mitochondria rich tumours reveals a coordinated up-regulation of genes involved in oxidative metabolism

O Baris , F Savagner , V Nasser , Béatrice B. Loriod , S Granjeaud
Biochimica biophysica acta (BBA) - Bioenergetics, 2004, 1657, pp.84-85
Article dans une revue hal-01612149v1

Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters

F Bertucci , S Salas , S Eysteries , V Nasser , P Finetti
Oncogene, 2004, 23 (7), pp.1377-1391. ⟨10.1038/sj.onc.1207262⟩
Article dans une revue hal-01612151v1

Small lymphocytic lymphoma, marginal zone B-cell lymphoma, and mantle cell lymphoma exhibit distinct gene-expression profiles allowing molecular diagnosis

C Thieblemont , V Nasser , P Felman , K Leroy , S Gazzo
Blood, 2004, 103 (7), pp.2727-2737. ⟨10.1182/blood-2003-06-2160⟩
Article dans une revue hal-01612152v1

Identification of new classes among acute myelogenous leukaemias with normal karyotype using gene expression profiling

Norbert Vey , Marie-Joëlle Mozziconacci , Agnès Groulet-Martinec , Stéphane Debono , Pascal Finetti
Oncogene, 2004, 23 (58), pp.9381-9391. ⟨10.1038/sj.onc.1207910⟩
Article dans une revue hal-03623840v1

Identification and validation of an ERBB2 gene expression signature in breast cancers

François Bertucci , Nathalie Borie , Christophe Ginestier , Agnès Groulet , Emmanuelle Charafe-Jauffret
Oncogene, 2004, 23 (14), pp.2564-2575. ⟨10.1038/sj.onc.1207361⟩
Article dans une revue hal-03623842v1

Transcriptional profiling reveals coordinated up-regulation of oxidative metabolism genes in thyroid oncocytic tumors

O Baris , F Savagner , V Nasser , Béatrice B. Loriod , S Granjeaud
Journal of Clinical Endocrinology and Metabolism, 2004, 89 (2), pp.994-1005. ⟨10.1210/jc.2003-031238⟩
Article dans une revue hal-01612150v1

Gene expression profiling of breast carcinomas using Nylon DNA arrays

F Bertucci , Béatrice B. Loriod , V Nasser , S Granjeaud , R Tagett
Comptes Rendus Biologies, 2003, 326 (10-11), pp.1031-1039. ⟨10.1016/j.crvi.2003.09.010⟩
Article dans une revue hal-01612156v1

Breast cancer revisited using DNA array-based gene expression profiling

François Bertucci , Patrice Viens , Pascal Hingamp , Valery Nasser , Rémi Houlgatte
International Journal of Cancer, 2003, 103 (5), pp.565-571. ⟨10.1002/ijc.10867⟩
Article dans une revue hal-03623846v1

Gene expression profiling of multiple myeloma reveals molecular portraits in relation to the pathogenesis of the disease

F Magrangeas , V Nasser , H Avet-Loiseau , Béatrice B. Loriod , O Decaux
Blood, 2003, 101 (12), pp.4998-5006. ⟨10.1182/blood-2002-11-3385⟩
Article dans une revue hal-01612158v1

Loss of FHIT protein expression is a marker of adverse evolution in good prognosis localized breast cancer

Christophe Ginestier , Valérie-Jeanne Bardou , Cornel Popovici , Emmanuelle Charafe-Jauffret , François Bertucci
International Journal of Cancer, 2003, 107 (5), pp.854-862. ⟨10.1002/ijc.11462⟩
Article dans une revue hal-03623844v1

DNA Arrays in Clinical Oncology: Promises and Challenges

François Bertucci , Patrice Viens , Rebecca Tagett , Catherine Nguyen , Rémi Houlgatte
Laboratory Investigation, 2003, 83 (3), pp.305-316. ⟨10.1097/01.lab.0000059936.28369.19⟩
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Reciprocal translocations in breast tumor cell lines: Cloning of a t(3;20) that targets the FHIT gene

C. Popovici , C. Basset , F. Bertucci , A. Orsetti , J. Adelaide
Genes, Chromosomes & Cancer, 2002, 35 (3), pp.204--218. ⟨10.1002/gcc.10107⟩
Article dans une revue hal-02197538v1

Gene expression profiles of poor-prognosis primary breast cancer correlate with survival

F Bertucci , V Nasser , S Granjeaud , F Eisinger , José Adelaïde
Human Molecular Genetics, 2002, 11 (8), pp.863-872. ⟨10.1093/hmg/11.8.863⟩
Article dans une revue hal-01612162v1

Distinct and Complementary Information Provided by Use of Tissue and DNA Microarrays in the Study of Breast Tumor Markers

Christophe Ginestier , Emmanuelle Charafe-Jauffret , François Bertucci , François Eisinger , Jeannine Geneix
American Journal of Pathology, 2002, 161 (4), pp.1223-1233. ⟨10.1016/s0002-9440(10)64399-4⟩
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Gene expression profiling defines molecular subtypes of classical Hodgkin's disease

Elisabeth Devilard , François Bertucci , Pascal Trempat , Réda Bouabdallah , Béatrice B. Loriod
Oncogene, 2002, 21 (19), pp.3095-3102. ⟨10.1038/sj.onc.1205418⟩
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Re: Gene Expression Profiles of BRCA1-Linked, BRCA2-Linked, and Sporadic Ovarian Cancers

François Bertucci , F. Eisinger , R. Tagett , H. Sobol , D. Birnbaum
JNCI: Journal of the National Cancer Institute, 2002, 94 (19), pp.1506-1507. ⟨10.1093/jnci/94.19.1506⟩
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Gene-expression profiling and identification of patients at high risk of breast cancer

François Bertucci , François Eisinger , Rémi Houlgatte , Patrice Viens , Daniel Birnbaum
The Lancet, 2002, 360 (9327), pp.173-174. ⟨10.1016/s0140-6736(02)09399-6⟩
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Modulations of dose intensity of doxorubicin and cyclophosphamide in association with G-CSF and peripheral blood stem cells in adjuvant chemotherapy for breast cancer: comparative evaluation of completion and safety of three intensive regimens

D. Genre , P. Viens , F. Bertucci , C Chabannon , G. Gravis
Bone Marrow Transplantation, 2002, 29 (11), pp.881-886. ⟨10.1038/sj.bmt.1703556⟩
Article dans une revue inserm-03199676v1

DNA arrays: technological aspects and applications

F Bertucci , Béatrice B. Loriod , R Tagett , S Granjeaud , D Birnbaum
Bulletin du Cancer, 2001, 88 (3), pp.243-252
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Molecular typing of breast cancer: transcriptomics and DNA microarrays

F Bertucci , R Houlgatte , C Nguyen , A Benziane , V Nasser
Bulletin du Cancer, 2001, 88 (3), pp.277-286
Article dans une revue hal-01612164v1

Gene expression profiling using nylon arrays of candidates genes

F Bertucci , Béatrice B. Loriod , R Houlgatte , C Nguyen
Journal of Neurochemistry, 2001, 78, pp.110
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Gene expression profiling of primary breast carcinomas using arrays of candidate genes

F Bertucci , R Houlgatte , A Benziane , S Granjeaud , José Adelaïde
Human Molecular Genetics, 2000, 9 (20), pp.2981-2991. ⟨10.1093/hmg/9.20.2981⟩
Article dans une revue hal-01612167v1

Sensitivity issues in DNA array-based expression measurements and performance of nylon microarrays for small samples

F Bertucci , K Bernard , Béatrice B. Loriod , Yi-Chung Chang , S Granjeaud
Human Molecular Genetics, 1999, 8 (9), pp.1715-1722. ⟨10.1093/hmg/8.9.1715⟩
Article dans une revue hal-01612169v1

Expression scanning of an array of growth control genes in human tumor cell lines

F Bertucci , S van Hulst , K Bernard , Béatrice B. Loriod , S Granjeaud
Oncogene, 1999, 18 (26), pp.3905-3912. ⟨10.1038/sj.onc.1202731⟩
Article dans une revue hal-01612170v1