FH

François Hallé

13
Documents

Publications

Publications

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Design, synthesis, and structure–activity relationship studies of 6 H -benzo[ b ]indeno[1,2- d ]thiophen-6-one derivatives as DYRK1A/CLK1/CLK4/haspin inhibitors

Abdelfattah Faouzi , Alexandre Arnaud , François Hallé , Jean Roussel , Mandy Aymard et al.
RSC Medicinal Chemistry, 2025, 16 (1), pp.179-199. ⟨10.1039/d4md00537f⟩
Article dans une revue hal-04961871 v1

A Journey through Hemetsberger–Knittel , Leimgruber–Batcho and Bartoli Reactions: Access to Several Hydroxy 5‐ and 6‐Azaindoles

Sylvie Radix , François Hallé , Zahia Mahiout , Amélie Teissonnière , Grégoire Bouchez et al.
Helvetica Chimica Acta, 2022, 105 (3), pp.370-375. ⟨10.1002/hlca.202100211⟩
Article dans une revue hal-04933425 v1
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Mitochondria modulatory effects of new TSPO ligands in a cellular model of tauopathies

Amandine Grimm , Imane Lejri , François Hallé , Martine Schmitt , Jürgen Götz et al.
Journal of Neuroendocrinology, 2019, ⟨10.1111/jne.12796⟩
Article dans une revue hal-02368671 v1
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TSPO Ligands Boost Mitochondrial Function and Pregnenolone Synthesis

Imane Lejri , Amandine Grimm , François Hallé , Mustapha Abarghaz , Christian Klein et al.
Journal of Alzheimer's Disease, In press, pp.1-14. ⟨10.3233/JAD-190127⟩
Article dans une revue hal-02368657 v1

Crystal structure and identification of a pyrimido[6,1-b][1,3]oxazin-6-one derivative from the reaction of acrolein with 5-(phenoxymethyl)-2-amino-2-oxazoline

Jean Guillon , Sandra Rubio , Solène Savrimoutou , François Hallé , Stéphane Moreau et al.
Comptes Rendus. Chimie, 2018, 21 (11), pp.987-992. ⟨10.1016/j.crci.2018.09.013⟩
Article dans une revue hal-01922305 v1
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Human erythrocytes release ATP by a novel pathway involving VDAC oligomerization independent of pannexin-1

Irene Marginedas-Freixa , Cora Lilia Alvarez , Martina Moras , María Florencia Leal Denis , Claude Hattab et al.
Scientific Reports, 2018, 8, pp.11384. ⟨10.1038/s41598-018-29885-7⟩
Article dans une revue hal-02368694 v1

Discovery of Imidazoquinazolinone Derivatives as TSPO Ligands Modulating Neurosteroidogenesis and Cellular Bioenergetics in Neuroblastoma Cells Expressing Amyloid Precursor Protein

François Hallé , Imane Lejri , Mustapha Abarghaz , Amandine Grimm , Christian Klein et al.
ChemistrySelect, 2017, 2 (22), pp.6452-6457. ⟨10.1002/slct.201701565⟩
Article dans une revue hal-02368811 v1

Emissive Synthetic Cofactors: Enzymatic Interconversions of tz A Analogues of ATP, NAD + , NADH, NADP + , and NADPH

François Hallé , Andrea Fin , Alexander Rovira , Yitzhak Tor
Angewandte Chemie International Edition, 2017, 57 (4), pp.1087-1090. ⟨10.1002/anie.201711935⟩
Article dans une revue hal-04934214 v1

The translocator protein ligand XBD173 improves clinical symptoms and neuropathological markers in the SJL/J mouse model of multiple sclerosis

I. Marginedas-Freixa , C. Hattab , G. Bouyer , F. Halle , A. Chene et al.
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2017, 1863 (12), pp.3016-3027. ⟨10.1016/j.bbadis.2017.09.007⟩
Article dans une revue hal-02290250 v1

χ-Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds

Olivier van Der Poorten , Robin van den Hauwe , Emilie Eiselt , Cecilia Betti , Karel Guillemyn et al.
ACS Medicinal Chemistry Letters, 2017, 8 (11), pp.1177-1182. ⟨10.1021/acsmedchemlett.7b00347⟩
Article dans une revue hal-02368778 v1
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TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood

I Marginedas-Freixa , C Hattab , G Bouyer , F Halle , A Chene et al.
Scientific Reports, 2016, 6, pp.33516 ⟨10.1038/srep33516⟩
Article dans une revue hal-01369499 v1

Synthesis of 3-amino-3,4-dihydro-1H-quinolin-2-ones through regioselective palladium-catalyzed intramolecular cyclization

François Hallé , Olivier van Der Poorten , Christelle Doebelin , Marie Niederst , Séverine Schneider et al.
Tetrahedron Letters, 2016, 57 (14), pp.1547-1550. ⟨10.1016/j.tetlet.2016.02.094⟩
Article dans une revue hal-02290245 v1