Francois HELLE

47
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Publications

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Development of a urinary antigen test for BK Polyomavirus to help clinicians in patients’ follow-up

Etienne Brochot , Ophélie Fourdinier , Baptiste Demey , Aurélien Aubry , Louison Collet et al.
Journal of Virological Methods, 2025, 333, pp.115113. ⟨10.1016/j.jviromet.2025.115113⟩
Article dans une revue hal-04934069 v1
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Intranasal spike and nucleoprotein fusion protein-based vaccine provides cross-protection and reduced transmission against SARS-CoV-2 variants

Zineb Lakhrif , Agathe Poupée-Beaugé , Fanny Boursin , Céline Ducournau , Louis Lantier et al.
NPJ vaccines, 2025, 10 (1), pp.75. ⟨10.1038/s41541-025-01123-y⟩
Article dans une revue hal-05046705 v1
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Epidemiology and Dynamics of BK Polyomavirus Replication after Kidney Transplantation

Etienne Brochot , Baptiste Demey , Aurélien Aubry , Véronique Descamps , Virginie Morel et al.
Pathogens, 2024, 13 (4), pp.315. ⟨10.3390/pathogens13040315⟩
Article dans une revue hal-04566613 v1

The value and complexity of studying cellular immunity against BK Polyomavirus in kidney transplant recipients

Aurélien Aubry , Baptiste Demey , Sandrine Castelain , François Helle , Etienne Brochot
Journal of Clinical Virology, 2024, pp.105656. ⟨10.1016/j.jcv.2024.105656⟩
Article dans une revue hal-04473948 v1

Molecular epidemiology and risk factors associated with BK and JC polyomavirus urinary shedding after kidney allograft

Baptiste Demey , Aurélien Aubry , Véronique Descamps , Virginie Morel , My Hanh Hillary Le et al.
Journal of Medical Virology, 2024, 96 (6), ⟨10.1002/jmv.29742⟩
Article dans une revue hal-04613379 v1
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The Conserved YPX3L Motif in the BK Polyomavirus VP1 Protein Is Important for Viral Particle Assembly but Not for Its Secretion into Extracellular Vesicles

Marine Bentz , Louison Collet , Virginie Morel , Véronique Descamps , Emmanuelle Blanchard et al.
Viruses, 2024, 16 (7), pp.1124. ⟨10.3390/v16071124⟩
Article dans une revue hal-04653798 v1

Neutralizing Antibodies Targeting BK Polyomavirus

Francois Helle , Aurélien Aubry , Virginie Morel , Véronique Descamps , Baptiste Demey et al.
Journal of the American Society of Nephrology, 2024, ⟨10.1681/ASN.0000000000000457⟩
Article dans une revue hal-04644527 v1

Comparison of two RT-qPCR methods targeting BK polyomavirus microRNAs in kidney transplant recipients

Kenza Zoubir , Véronique Descamps , Aurélien Aubry , Francois Helle , Catherine Francois et al.
Frontiers in Medicine, 2023, 10, pp.1281625. ⟨10.3389/fmed.2023.1281625⟩
Article dans une revue hal-04391468 v1
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BK Polyomavirus Bkv-miR-B1-5p: A Stable Micro-RNA to Monitor Active Viral Replication after Kidney Transplantation.

Baptiste Demey , Marine Bentz , Véronique Descamps , Virginie Morel , Catherine Francois et al.
International Journal of Molecular Sciences, 2022, 23 (13), ⟨10.3390/ijms23137240⟩
Article dans une revue hal-03723437 v1

Kinetics of SARS-CoV-2-Neutralising Antibodies of Residents of Long-Term Care Facilities

Sophie Liabeuf , Jean-Luc Schmit , Jean-Philippe Lanoix , Sandrine Castelain , Frederic Bloch et al.
Journal of Nutrition, Health & Aging, 2022, 26 (1), pp.57-63. ⟨10.1007/s12603-021-1713-4⟩
Article dans une revue hal-03578461 v1
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Humoral anti-SARS-CoV-2 immune response after two doses of Comirnaty vaccine in nursing home residents by previous infection status

Baptiste Demey , Catherine Francois , Gilles Duverlie , Sandrine Castelain , Frederic Bloch et al.
Vaccine, 2022, 40 (3), pp.531-535. ⟨10.1016/j.vaccine.2021.11.086⟩
Article dans une revue hal-03692572 v1

The impact of pre-graft serology on the risk of BKPyV infection post-renal transplantation

Fatima Dakroub , Antoine Touzé , Fadi Abdel Sater , Toni Fiore , Virginie Morel et al.
Nephrology Dialysis Transplantation, 2022, 37 (4), pp.781-788. ⟨10.1093/ndt/gfab279⟩
Article dans une revue hal-03413373 v1

Les virus : des dompteurs de vésicules

Lynda Handala , Francois Helle
Virologie, 2021, 25 (6), pp.326-332. ⟨10.1684/vir.2021.0923⟩
Article dans une revue hal-03592395 v1
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Longitudinal Analysis and Comparison of Six Serological Assays up to Eight Months Post-COVID-19 Diagnosis

Aurelien Aubry , Baptiste Demey , Catherine Francois , Gilles Duverlie , Sandrine Castelain et al.
Journal of Clinical Medicine, 2021, 10 (9), ⟨10.3390/jcm10091815⟩
Article dans une revue hal-03591561 v1
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BK Polyomavirus Micro-RNAs: Time Course and Clinical Relevance in Kidney Transplant Recipients

Baptiste Demey , Veronique Descamps , Claire Presne , Francois Helle , Catherine Francois et al.
Viruses, 2021, 13 (2), ⟨10.3390/v13020351⟩
Article dans une revue hal-03591564 v1

Neutralizing antibodies directed against SARS-CoV-2 in a population residing in a nursing home and a long-term care unit

Julien Moyet , Francois Helle , Gwladys Bourdenet , Cedric Joseph , Brigitte Gubler et al.
Geriatrics and Gerontology International, 2021, 21 (11), pp.1066-1068. ⟨10.1111/ggi.14289⟩
Article dans une revue hal-03591557 v1
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BK Polyomavirus Hijacks Extracellular Vesicles for En Bloc Transmission

Lynda Handala , Emmanuelle Blanchard , Pierre-Ivan Raynal , Philippe Roingeard , Virginie Morel et al.
Journal of Virology, 2020, 94 (6), pp.e01834-19. ⟨10.1128/JVI.01834-19⟩
Article dans une revue hal-03591569 v1
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Anti-spike, Anti-nucleocapsid and Neutralizing Antibodies in SARS-CoV-2 Inpatients and Asymptomatic Individuals

Etienne Brochot , Baptiste Demey , Antoine Touzé , Sandrine Belouzard , Jean Dubuisson et al.
Frontiers in Microbiology, 2020, 11 (584251), 8 p. ⟨10.3389/fmicb.2020.584251⟩
Article dans une revue hal-03058488 v1
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Indoleamine 2,3-Dioxygenase Is Involved in Interferon Gamma's Anti-BKPyV Activity in Renal Cells

Tony Fiore , Elodie Martin , Veronique Descamps , Etienne Brochot , Virginie Morel et al.
Viruses, 2020, 12 (8), ⟨10.3390/v12080865⟩
Article dans une revue hal-03591567 v1
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Intercellular Transmission of Naked Viruses through Extracellular Vesicles: Focus on Polyomaviruses

Francois Helle , Lynda Handala , Marine Bentz , Gilles Duverlie , Etienne Brochot
Viruses, 2020, 12 (10), ⟨10.3390/v12101086⟩
Article dans une revue hal-03591566 v1
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No correlation between Torque Teno virus viral load and BK virus replication after kidney transplantation

Lynda Handala , Véronique Descamps , Virginie Morel , Sandrine Castelain , Catherine François et al.
Journal of Clinical Virology, 2019, 116, pp.4 - 6. ⟨10.1016/j.jcv.2019.03.018⟩
Article dans une revue hal-03485972 v1

BK polyomavirus in the urine for follow-up of kidney transplant recipients

Etienne Brochot , Véronique Descamps , Lynda Handala , Justine Faucher , Gabriel Choukroun et al.
Clinical Microbiology and Infection, 2019, 25 (1), pp.112.e1-112.e5. ⟨10.1016/j.cmi.2018.07.027⟩
Article dans une revue hal-02622119 v1

Correction: Permissivity of Primary Human Hepatocytes and Different Hepatoma Cell Lines to Cell Culture Adapted Hepatitis C Virus

Francois Helle , Etienne Brochot , Carole Fournier , Veronique Descamps , Laure Izquierdo et al.
PLoS ONE, 2019, 14 (9), pp.e0223022. ⟨10.1371/journal.pone.0223022⟩
Article dans une revue hal-03591570 v1
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QuantIF: An ImageJ Macro to Automatically Determine the Percentage of Infected Cells after Immunofluorescence

Lynda Handala , Tony Fiore , Yves Rouillé , Francois Helle
Viruses, 2019, 11 (2), pp.165. ⟨10.3390/v11020165⟩
Article dans une revue hal-02114383 v1

Risk factors for BK virus viremia and nephropathy after kidney transplantation: A systematic review

Baptiste Demey , Claire Tinez , Catherine Francois , Francois Helle , Gabriel Choukroun et al.
Journal of Clinical Virology, 2018, 109, pp.6-12. ⟨10.1016/j.jcv.2018.10.002⟩
Article dans une revue hal-03573107 v1
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Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry

Laura Riva , Ok-Ryul Song , Jannick Prentoe , Francois Helle , Laurent L'Homme et al.
Journal of Virology, 2018, 92 (10), pp.e01982-17. ⟨10.1128/JVI.01982-17⟩
Article dans une revue hal-02112504 v1
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Claudin-1, miR-122 and apolipoprotein E transductions improve the permissivity of SNU-182, SNU-398 and SNU-449 hepatoma cells to hepatitis C virus

Carole Fournier , Thomas Walter Hoffmann , Virginie Morel , Véronique Descamps , Jean Dubuisson et al.
Journal of Viral Hepatitis, 2018, 25 (1), pp.63-71. ⟨10.1111/jvh.12767⟩
Article dans une revue hal-02112514 v1

The expression of HCV-associated host factors is dependent on the hepatoma cell line used in HCV studies (vol 159, pg 527, 2014)

Thomas Walter Hoffmann , Fabien Delfosse , Francois Helle , Catherine Francois , Gilles Duverlie et al.
Archives of Virology, 2018, 163 (12), pp.3485. ⟨10.1007/s00705-018-4044-y⟩
Article dans une revue hal-03592192 v1
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Hepatitis E Virus Lifecycle and Identification of 3 Forms of the ORF2 Capsid Protein

Claire Montpellier , Czeslaw Wychowski , Ibrahim M Sayed , Jean-Christophe Meunier , Jean-Michel Saliou et al.
Gastroenterology, 2018, 154 (1), pp.211-223.e8. ⟨10.1053/j.gastro.2017.09.020⟩
Article dans une revue hal-02117643 v1
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Apolipoprotein(a) Inhibits Hepatitis C Virus Entry Through Interaction With Infectious Particles

Catarina Oliveira , Carole Fournier , Veronique Descamps , Virginie Morel , Corey A. Scipione et al.
Hepatology, 2017, 65 (6), pp.1851-1864. ⟨10.1002/hep.29096⟩
Article dans une revue hal-03568255 v1

High association of T1858-G1896 precore mutations with impaired base pairing and high hepatitis B virus DNA levels in HBeAg-negative chronically infected patients

Sandrine Castelain , Veronique Descamps , Etienne Brochot , Francois Helle , Gilles Duverlie et al.
Archives of Virology, 2017, 162 (7), pp.1913-1920. ⟨10.1007/s00705-017-3312-6⟩
Article dans une revue hal-03590929 v1

A Simple and Reliable Strategy for BK Virus Subtyping and Subgrouping

Virginie Morel , Elodie Martin , Catherine Francois , Francois Helle , Justine Faucher et al.
Journal of Clinical Microbiology, 2017, 55 (4), pp.1177-1185. ⟨10.1128/JCM.01180-16⟩
Article dans une revue hal-03574259 v1
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Biology of the BKPyV: An Update

Francois Helle , Etienne Brochot , Lynda Handala , Elodie Martin , Sandrine Castelain et al.
Viruses, 2017, 9 (11), ⟨10.3390/v9110327⟩
Article dans une revue hal-03591576 v1

DHEA prevents ribavirin-induced anemia via inhibition of glucose-6-phosphate dehydrogenase

Lynda Handala , Barbara Domange , Hakim Ouled-Haddou , Loic Garcon , Eric Nguyen-Khac et al.
Antiviral Research, 2017, 146, pp.153-160. ⟨10.1016/j.antiviral.2017.09.002⟩
Article dans une revue hal-03589430 v1

Antiviral effect of interferons on BK virus infection

E. Martin , Véronique Descamps , Virginie Morel , François Helle , Etienne Brochot et al.
Journal of Clinical Virology, 2016, 82 (S), pp.S16-S17. ⟨10.1016/j.jcv.2016.08.030⟩
Article dans une revue hal-03591578 v1

Ribavirin restores IFNα responsiveness in HCV-infected livers by epigenetic remodelling at interferon stimulated genes

Barbara Testoni , David Durantel , Fanny Lebossé , Judith Fresquet , François Helle et al.
Gut, 2016, 65 (4), pp.672-682. ⟨10.1136/gutjnl-2014-309011⟩
Article dans une revue hal-01796188 v1
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Hepatitis C Virus Resistance to Carbohydrate-Binding Agents

Laure Izquierdo , Catarina Oliveira , Carole Fournier , Veronique Descamps , Virginie Morel et al.
PLoS ONE, 2016, 11 (2), pp.e0149064. ⟨10.1371/journal.pone.0149064⟩
Article dans une revue hal-03591579 v1

Phylogenetic analysis of a circulating hepatitis C virus recombinant strain 1b/1a isolated in a French hospital centre

Virginie Morel , Faten Ghoubra , Laure Izquierdo , Elodie Martin , Catarina Oliveira et al.
Infection, Genetics and Evolution, 2016, 40, pp.374-380. ⟨10.1016/j.meegid.2015.09.030⟩
Article dans une revue pasteur-01375000 v1
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Claudin-6 and Occludin Natural Variants Found in a Patient Highly Exposed but Not Infected with Hepatitis C Virus (HCV) Do Not Confer HCV Resistance In Vitro

Lucie Fénéant , Jade Ghosn , Baptiste Fouquet , Francois Helle , Sandrine Belouzard et al.
PLoS ONE, 2015, 10 (11), pp.e0142539. ⟨10.1371/journal.pone.0142539⟩
Article dans une revue hal-02104504 v1
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Up-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection.

Simone Bocchetta , Patrick Maillard , Mami Yamamoto , Claire Gondeau , Florian Douam et al.
PLoS ONE, 2014, 9 (3), pp.e92140. ⟨10.1371/journal.pone.0092140⟩
Article dans une revue hal-01010585 v1

In vitro infection of primary human hepatocytes by HCV-positive sera: insights on a highly relevant model

Claire Gondeau , Philippe Briolotti , Francia Razafy , Cédric Duret , Pierre-Alain Rubbo et al.
Gut, 2014, 63 (9), pp.1490-1500. ⟨10.1136/gutjnl-2013-304623⟩
Article dans une revue hal-03082070 v1

Disulfide bonds in hepatitis C virus glycoprotein E1 control the assembly and entry functions of E2 glycoprotein.

Ahmed Wahid , François Helle , Véronique Descamps , Gilles Duverlie , François Penin et al.
Journal of Virology, 2013, 87 (3), pp.1605-17. ⟨10.1128/JVI.02659-12⟩
Article dans une revue hal-00965769 v1

The antimalarial ferroquine is an inhibitor of hepatitis C virus

Thibaut Vausselin , Noémie Calland , Sandrine Belouzard , Véronique Descamps , Florian Douam et al.
Hepatology, 2013, Hepatology, 58 (1), pp.86-97. ⟨10.1002/hep.26273⟩
Article dans une revue hal-03153561 v1

The neutralizing activity of anti-HCV antibodies is modulated by specific glycans on the E2 envelope protein

Francois Helle , Anne Goffard , Virginie Morel , Gilles Duverlie , Jane Mckeating et al.
Journal of Virology, 2007, 81 (15), pp.8101-8111. ⟨10.1128/JVI.00127-07⟩
Article dans une revue hal-00183359 v1

Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus.

Yves Rouillé , Francois Helle , David Delgrange , Philippe Roingeard , Cécile Voisset et al.
Journal of Virology, 2006, 80, pp.2832-2841. ⟨10.1128/JVI.80.6.2832-2841.2006⟩
Article dans une revue hal-00105500 v1

Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycans.

Francois Helle , Czeslaw Wychowski , Ngoc Vu-Dac , Kirk Gustafson , Cécile Voisset et al.
Journal of Biological Chemistry, 2006, 281, pp.25177-25183. ⟨10.1074/jbc.M602431200⟩
Article dans une revue hal-00105507 v1

Enantiopure aminoaryl-alcohols with fluorene core to antimalarial activity

Jeremy Schneider , Bruno Pradines , François Helle , Alexandra Dassonville-Klimpt , Nicolas Taudon et al.
4th International Electronic Conference on Medicinal Chemistry, Nov 2018, Sciforum.net, France. pp.5575, ⟨10.3390/ecmc-4-05575⟩
Communication dans un congrès hal-03708995 v1