Francois HELLE

Publications

Article dans une revue (49)

A rapid immunochromatographic assay for the detection of BK Polyomavirus in urine samples from hematopoietic stem cell transplant recipients Etienne Brochot,Etienne Paubelle,Ophélie Fourdinier,Baptiste Demey,Aurélien Aubryet al. Journal of Virological Methods, 2026, 341, pp.115321. ⟨10.1016/j.jviromet.2025.115321⟩ Article dans une revue hal-05411964v1
JC polyomavirus-encoded miRNA jcv-miR-J1-5p downregulates BK polyomavirus infection Baptiste Demey,Aurélien Aubry,Virginie Morel,Louison Collet,Catherine Francoiset al. Antiviral Research, 2026, 245, pp.106313. ⟨10.1016/j.antiviral.2025.106313⟩ Article dans une revue hal-05398960v1
Development of a urinary antigen test for BK Polyomavirus to help clinicians in patients’ follow-up Etienne Brochot,Ophélie Fourdinier,Baptiste Demey,Aurélien Aubry,Louison Colletet al. Journal of Virological Methods, 2025, 333, pp.115113. ⟨10.1016/j.jviromet.2025.115113⟩ Article dans une revue hal-04934069v1
Intranasal spike and nucleoprotein fusion protein-based vaccine provides cross-protection and reduced transmission against SARS-CoV-2 variants Zineb Lakhrif,Agathe Poupée-Beaugé,Fanny Boursin,Céline Ducournau,Louis Lantieret al. NPJ vaccines, 2025, 10 (1), pp.75. ⟨10.1038/s41541-025-01123-y⟩ Article dans une revue hal-05046705v1
HLA ‐B Leader Dimorphism Predicts BK Polyomavirus Replication After Kidney Transplant Aurélien Aubry,Baptiste Demey,François Helle,Ophélie Fourdinier,Julien Lionet al. HLA: Immune Response Genetics, 2025, 106 (5), pp.e70477. ⟨10.1111/tan.70477⟩ Article dans une revue hal-05381643v1
Epidemiology and Dynamics of BK Polyomavirus Replication after Kidney Transplantation Etienne Brochot,Baptiste Demey,Aurélien Aubry,Véronique Descamps,Virginie Morelet al. Pathogens, 2024, 13 (4), pp.315. ⟨10.3390/pathogens13040315⟩ Article dans une revue hal-04566613v1
Molecular epidemiology and risk factors associated with BK and JC polyomavirus urinary shedding after kidney allograft Baptiste Demey,Aurélien Aubry,Véronique Descamps,Virginie Morel,My Hanh Hillary Leet al. Journal of Medical Virology, 2024, 96 (6), pp.e29742. ⟨10.1002/jmv.29742⟩ Article dans une revue hal-04613379v1
The value and complexity of studying cellular immunity against BK Polyomavirus in kidney transplant recipients Aurélien Aubry,Baptiste Demey,Sandrine Castelain,François Helle,Etienne Brochot Journal of Clinical Virology, 2024, pp.105656. ⟨10.1016/j.jcv.2024.105656⟩ Article dans une revue hal-04473948v1
Neutralizing Antibodies Targeting BK Polyomavirus Francois Helle,Aurélien Aubry,Virginie Morel,Véronique Descamps,Baptiste Demeyet al. Journal of the American Society of Nephrology, 2024, 35 (10), pp.1425-1433. ⟨10.1681/ASN.0000000000000457⟩ Article dans une revue hal-04644527v1
The Conserved YPX3L Motif in the BK Polyomavirus VP1 Protein Is Important for Viral Particle Assembly but Not for Its Secretion into Extracellular Vesicles Marine Bentz,Louison Collet,Virginie Morel,Véronique Descamps,Emmanuelle Blanchardet al. Viruses, 2024, 16 (7), pp.1124. ⟨10.3390/v16071124⟩ Article dans une revue hal-04653798v1
Comparison of two RT-qPCR methods targeting BK polyomavirus microRNAs in kidney transplant recipients Kenza Zoubir,Véronique Descamps,Aurélien Aubry,Francois Helle,Catherine Francoiset al. Frontiers in Medicine, 2023, 10, pp.1281625. ⟨10.3389/fmed.2023.1281625⟩ Article dans une revue hal-04391468v1
BK Polyomavirus Bkv-miR-B1-5p: A Stable Micro-RNA to Monitor Active Viral Replication after Kidney Transplantation. Baptiste Demey,Marine Bentz,Véronique Descamps,Virginie Morel,Catherine Francoiset al. International Journal of Molecular Sciences, 2022, 23 (13), ⟨10.3390/ijms23137240⟩ Article dans une revue hal-03723437v1
Kinetics of SARS-CoV-2-Neutralising Antibodies of Residents of Long-Term Care Facilities Sophie Liabeuf,Jean-Luc Schmit,Jean-Philippe Lanoix,Sandrine Castelain,Frederic Blochet al. Journal of Nutrition, Health & Aging, 2022, 26 (1), pp.57-63. ⟨10.1007/s12603-021-1713-4⟩ Article dans une revue hal-03578461v1
Humoral anti-SARS-CoV-2 immune response after two doses of Comirnaty vaccine in nursing home residents by previous infection status Baptiste Demey,Catherine Francois,Gilles Duverlie,Sandrine Castelain,Frederic Blochet al. Vaccine, 2022, 40 (3), pp.531-535. ⟨10.1016/j.vaccine.2021.11.086⟩ Article dans une revue hal-03692572v1
The impact of pre-graft serology on the risk of BKPyV infection post-renal transplantation Fatima Dakroub,Antoine Touzé,Fadi Abdel Sater,Toni Fiore,Virginie Morelet al. Nephrology Dialysis Transplantation, 2022, 37 (4), pp.781-788. ⟨10.1093/ndt/gfab279⟩ Article dans une revue hal-03413373v1
Les virus : des dompteurs de vésicules Lynda Handala,Francois Helle Virologie, 2021, 25 (6), pp.326-332. ⟨10.1684/vir.2021.0923⟩ Article dans une revue hal-03592395v1
Longitudinal Analysis and Comparison of Six Serological Assays up to Eight Months Post-COVID-19 Diagnosis Aurelien Aubry,Baptiste Demey,Catherine Francois,Gilles Duverlie,Sandrine Castelainet al. Journal of Clinical Medicine, 2021, 10 (9), ⟨10.3390/jcm10091815⟩ Article dans une revue hal-03591561v1
Neutralizing antibodies directed against SARS-CoV-2 in a population residing in a nursing home and a long-term care unit Julien Moyet,Francois Helle,Gwladys Bourdenet,Cedric Joseph,Brigitte Gubleret al. Geriatrics and Gerontology International, 2021, 21 (11), pp.1066-1068. ⟨10.1111/ggi.14289⟩ Article dans une revue hal-03591557v1
BK Polyomavirus Micro-RNAs: Time Course and Clinical Relevance in Kidney Transplant Recipients Baptiste Demey,Veronique Descamps,Claire Presne,Francois Helle,Catherine Francoiset al. Viruses, 2021, 13 (2), ⟨10.3390/v13020351⟩ Article dans une revue hal-03591564v1
Anti-spike, Anti-nucleocapsid and Neutralizing Antibodies in SARS-CoV-2 Inpatients and Asymptomatic Individuals Etienne Brochot,Baptiste Demey,Antoine Touzé,Sandrine Belouzard,Jean Dubuissonet al. Frontiers in Microbiology, 2020, 11 (584251), 8 p. ⟨10.3389/fmicb.2020.584251⟩ Article dans une revue hal-03058488v1
BK Polyomavirus Hijacks Extracellular Vesicles for En Bloc Transmission Lynda Handala,Emmanuelle Blanchard,Pierre-Ivan Raynal,Philippe Roingeard,Virginie Morelet al. Journal of Virology, 2020, 94 (6), pp.e01834-19. ⟨10.1128/JVI.01834-19⟩ Article dans une revue hal-03591569v1
Indoleamine 2,3-Dioxygenase Is Involved in Interferon Gamma's Anti-BKPyV Activity in Renal Cells Tony Fiore,Elodie Martin,Veronique Descamps,Etienne Brochot,Virginie Morelet al. Viruses, 2020, 12 (8), ⟨10.3390/v12080865⟩ Article dans une revue hal-03591567v1
Intercellular Transmission of Naked Viruses through Extracellular Vesicles: Focus on Polyomaviruses Francois Helle,Lynda Handala,Marine Bentz,Gilles Duverlie,Etienne Brochot Viruses, 2020, 12 (10), ⟨10.3390/v12101086⟩ Article dans une revue hal-03591566v1
No correlation between Torque Teno virus viral load and BK virus replication after kidney transplantation Lynda Handala,Véronique Descamps,Virginie Morel,Sandrine Castelain,Catherine Françoiset al. Journal of Clinical Virology, 2019, 116, pp.4 - 6. ⟨10.1016/j.jcv.2019.03.018⟩ Article dans une revue hal-03485972v1
BK polyomavirus in the urine for follow-up of kidney transplant recipients Etienne Brochot,Véronique Descamps,Lynda Handala,Justine Faucher,Gabriel Choukrounet al. Clinical Microbiology and Infection, 2019, 25 (1), pp.112.e1-112.e5. ⟨10.1016/j.cmi.2018.07.027⟩ Article dans une revue hal-02622119v1
Correction: Permissivity of Primary Human Hepatocytes and Different Hepatoma Cell Lines to Cell Culture Adapted Hepatitis C Virus Francois Helle,Etienne Brochot,Carole Fournier,Veronique Descamps,Laure Izquierdoet al. PLoS ONE, 2019, 14 (9), pp.e0223022. ⟨10.1371/journal.pone.0223022⟩ Article dans une revue hal-03591570v1
QuantIF: An ImageJ Macro to Automatically Determine the Percentage of Infected Cells after Immunofluorescence Lynda Handala,Tony Fiore,Yves Rouillé,Francois Helle Viruses, 2019, 11 (2), pp.165. ⟨10.3390/v11020165⟩ Article dans une revue hal-02114383v1
Claudin-1, miR-122 and apolipoprotein E transductions improve the permissivity of SNU-182, SNU-398 and SNU-449 hepatoma cells to hepatitis C virus Carole Fournier,Thomas Walter Hoffmann,Virginie Morel,Véronique Descamps,Jean Dubuissonet al. Journal of Viral Hepatitis, 2018, 25 (1), pp.63-71. ⟨10.1111/jvh.12767⟩ Article dans une revue hal-02112514v1
Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry Laura Riva,Ok-Ryul Song,Jannick Prentoe,Francois Helle,Laurent L'Hommeet al. Journal of Virology, 2018, 92 (10), pp.e01982-17. ⟨10.1128/JVI.01982-17⟩ Article dans une revue hal-02112504v1
Risk factors for BK virus viremia and nephropathy after kidney transplantation: A systematic review Baptiste Demey,Claire Tinez,Catherine Francois,Francois Helle,Gabriel Choukrounet al. Journal of Clinical Virology, 2018, 109, pp.6-12. ⟨10.1016/j.jcv.2018.10.002⟩ Article dans une revue hal-03573107v1
The expression of HCV-associated host factors is dependent on the hepatoma cell line used in HCV studies (vol 159, pg 527, 2014) Thomas Walter Hoffmann,Fabien Delfosse,Francois Helle,Catherine Francois,Gilles Duverlieet al. Archives of Virology, 2018, 163 (12), pp.3485. ⟨10.1007/s00705-018-4044-y⟩ Article dans une revue hal-03592192v1
Hepatitis E Virus Lifecycle and Identification of 3 Forms of the ORF2 Capsid Protein Claire Montpellier,Czeslaw Wychowski,Ibrahim M Sayed,Jean-Christophe Meunier,Jean-Michel Saliouet al. Gastroenterology, 2018, 154 (1), pp.211-223.e8. ⟨10.1053/j.gastro.2017.09.020⟩ Article dans une revue hal-02117643v1
Apolipoprotein(a) Inhibits Hepatitis C Virus Entry Through Interaction With Infectious Particles Catarina Oliveira,Carole Fournier,Veronique Descamps,Virginie Morel,Corey A. Scipioneet al. Hepatology, 2017, 65 (6), pp.1851-1864. ⟨10.1002/hep.29096⟩ Article dans une revue hal-03568255v1
High association of T1858-G1896 precore mutations with impaired base pairing and high hepatitis B virus DNA levels in HBeAg-negative chronically infected patients Sandrine Castelain,Veronique Descamps,Etienne Brochot,Francois Helle,Gilles Duverlieet al. Archives of Virology, 2017, 162 (7), pp.1913-1920. ⟨10.1007/s00705-017-3312-6⟩ Article dans une revue hal-03590929v1
A Simple and Reliable Strategy for BK Virus Subtyping and Subgrouping Virginie Morel,Elodie Martin,Catherine Francois,Francois Helle,Justine Faucheret al. Journal of Clinical Microbiology, 2017, 55 (4), pp.1177-1185. ⟨10.1128/JCM.01180-16⟩ Article dans une revue hal-03574259v1
DHEA prevents ribavirin-induced anemia via inhibition of glucose-6-phosphate dehydrogenase Lynda Handala,Barbara Domange,Hakim Ouled-Haddou,Loic Garcon,Eric Nguyen-Khacet al. Antiviral Research, 2017, 146, pp.153-160. ⟨10.1016/j.antiviral.2017.09.002⟩ Article dans une revue hal-03589430v1
Biology of the BKPyV: An Update Francois Helle,Etienne Brochot,Lynda Handala,Elodie Martin,Sandrine Castelainet al. Viruses, 2017, 9 (11), ⟨10.3390/v9110327⟩ Article dans une revue hal-03591576v1
Antiviral effect of interferons on BK virus infection E. Martin,Véronique Descamps,Virginie Morel,François Helle,Etienne Brochotet al. Journal of Clinical Virology, 2016, 82 (S), pp.S16-S17. ⟨10.1016/j.jcv.2016.08.030⟩ Article dans une revue hal-03591578v1
Ribavirin restores IFNα responsiveness in HCV-infected livers by epigenetic remodelling at interferon stimulated genes Barbara Testoni,David Durantel,Fanny Lebossé,Judith Fresquet,François Helleet al. Gut, 2016, 65 (4), pp.672-682. ⟨10.1136/gutjnl-2014-309011⟩ Article dans une revue hal-01796188v1
Hepatitis C Virus Resistance to Carbohydrate-Binding Agents Laure Izquierdo,Catarina Oliveira,Carole Fournier,Veronique Descamps,Virginie Morelet al. PLoS ONE, 2016, 11 (2), pp.e0149064. ⟨10.1371/journal.pone.0149064⟩ Article dans une revue hal-03591579v1
Phylogenetic analysis of a circulating hepatitis C virus recombinant strain 1b/1a isolated in a French hospital centre Virginie Morel,Faten Ghoubra,Laure Izquierdo,Elodie Martin,Catarina Oliveiraet al. Infection, Genetics and Evolution, 2016, 40, pp.374-380. ⟨10.1016/j.meegid.2015.09.030⟩ Article dans une revue pasteur-01375000v1
Claudin-6 and Occludin Natural Variants Found in a Patient Highly Exposed but Not Infected with Hepatitis C Virus (HCV) Do Not Confer HCV Resistance In Vitro Lucie Fénéant,Jade Ghosn,Baptiste Fouquet,Francois Helle,Sandrine Belouzardet al. PLoS ONE, 2015, 10 (11), pp.e0142539. ⟨10.1371/journal.pone.0142539⟩ Article dans une revue hal-02104504v1
Up-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection. Simone Bocchetta,Patrick Maillard,Mami Yamamoto,Claire Gondeau,Florian Douamet al. PLoS ONE, 2014, 9 (3), pp.e92140. ⟨10.1371/journal.pone.0092140⟩ Article dans une revue hal-01010585v1
In vitro infection of primary human hepatocytes by HCV-positive sera: insights on a highly relevant model Claire Gondeau,Philippe Briolotti,Francia Razafy,Cédric Duret,Pierre-Alain Rubboet al. Gut, 2014, 63 (9), pp.1490-1500. ⟨10.1136/gutjnl-2013-304623⟩ Article dans une revue hal-03082070v1
Disulfide bonds in hepatitis C virus glycoprotein E1 control the assembly and entry functions of E2 glycoprotein. Ahmed Wahid,François Helle,Véronique Descamps,Gilles Duverlie,François Peninet al. Journal of Virology, 2013, 87 (3), pp.1605-17. ⟨10.1128/JVI.02659-12⟩ Article dans une revue hal-00965769v1
The antimalarial ferroquine is an inhibitor of hepatitis C virus Thibaut Vausselin,Noémie Calland,Sandrine Belouzard,Véronique Descamps,Florian Douamet al. Hepatology, 2013, Hepatology, 58 (1), pp.86-97. ⟨10.1002/hep.26273⟩ Article dans une revue hal-03153561v1
The neutralizing activity of anti-HCV antibodies is modulated by specific glycans on the E2 envelope protein Francois Helle,Anne Goffard,Virginie Morel,Gilles Duverlie,Jane Mckeatinget al. Journal of Virology, 2007, 81 (15), pp.8101-8111. ⟨10.1128/JVI.00127-07⟩ Article dans une revue hal-00183359v1
Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycans. Francois Helle,Czeslaw Wychowski,Ngoc Vu-Dac,Kirk Gustafson,Cécile Voissetet al. Journal of Biological Chemistry, 2006, 281, pp.25177-25183. ⟨10.1074/jbc.M602431200⟩ Article dans une revue hal-00105507v1
Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus. Yves Rouillé,Francois Helle,David Delgrange,Philippe Roingeard,Cécile Voissetet al. Journal of Virology, 2006, 80, pp.2832-2841. ⟨10.1128/JVI.80.6.2832-2841.2006⟩ Article dans une revue hal-00105500v1

Communication dans un congrès (1)

Enantiopure aminoaryl-alcohols with fluorene core to antimalarial activity Jeremy Schneider,Bruno Pradines,François Helle,Alexandra Dassonville-Klimpt,Nicolas Taudonet al. 4th International Electronic Conference on Medicinal Chemistry, Nov 2018, Sciforum.net, France. pp.5575, ⟨10.3390/ecmc-4-05575⟩ Communication dans un congrès hal-03708995v1