François ROBIN Francois B Robin, LBD-IBPS group leader

Identifiants chercheurs

IdHAL :

francois-robin

ORCID :

0000-0002-2420-2593

IdRef :

137577176

ResearcherID :

https://publons.com/researcher/4125305/francois-b-robin/

Présentation

François Robin is the leader of the CADMO team at the LBD-IBPS. His research group studies the dynamics of actomyosin systems during early embryonic development and morphogenesis.

His group works to understand how embryos change shape during development: they are interested in the biological processes that control the mechanical properties of cells, focusing on the actomyosin cortex. Specifically, their objective is to understand how actomyosin biochemistry drives the assembly of specific structures that control cell mechanics and eventually morphogenesis. To address this question, they combine a variety of approaches from different fields, and in particular quantitative live cell imaging, genetics, optogenetics, biophysics and biochemistry.

François trained in Biology at the Ecole Normale Supérieure and in Physical Chemistry at the École Normale Supérieure de Cachan (1999-2004). For his PhD, he joined the group of Patrick Lemaire, at the Institut de Biologie du Développement de Marseille, to study the cellular control of morphogenesis. To gain insight into the molecular and physical mechanisms that control cell shape changes, he then decided to shift model organisms and use the nematode C. elegans. To this end, he initiated a post-doc under the mentorship of Ed Munro, first at the University of Washington then at the University of Chicago. During this time, he developed innovative imaging techniques to visualize individual molecules at the cell surface in living embryos (single-molecule microscopy). This approach changed our perspective on how the dynamics of living systems emerge from the coordination of events at the molecular scale. In 2014, François came back to France. In 2016, he was laureate of the ATIP/Avenir program and was recruited on an open call to lead an independent research group at the Institut de Biologie Paris-Seine, in Paris. Since 2016, he is a researcher at Inserm.

Publications

Article dans une revue (16)

Genetically encoded reporters of actin filament organization in living cells and tissues Carla Silva Martins,Francois Iv,Shashi Kumar Suman,Thomas Panagiotou,Clara Sidoret al. Cell, 2025, 188 (9), pp.2540-2559. ⟨10.1016/j.cell.2025.03.003⟩ Article dans une revue hal-04563732v3
Rapid assembly of a polar network architecture drives efficient actomyosin contractility Vlad Costache,Serena Prigent Garcia,Camille N Plancke,Jing Li,Simon Begnaudet al. Cell Reports, 2022, 39 (9), pp.110868. ⟨10.1016/j.celrep.2022.110868⟩ Article dans une revue hal-03874348v2
High resolution dynamic mapping of the C. elegans intestinal brush border Aurélien Bidaud-Meynard,Flora Demouchy,Ophélie Nicolle,Anne Pacquelet,Shashi Kumar Sumanet al. Development (Cambridge, England), 2021, 148 (23), ⟨10.1242/dev.200029⟩ Article dans une revue hal-03426601v1
The role of mode switching in a population of actin polymers with constraints François Robin,Anne van Gorp,Amandine Véber Journal of Mathematical Biology, 2021, 82, ⟨10.1007/s00285-021-01551-z⟩ Article dans une revue hal-02301970v2
The plakin domain of C. elegans VAB-10/plectin acts as a hub in a mechanotransduction pathway to promote morphogenesis Shashi Kumar Suman,Csaba Daday,Teresa Ferraro,Thanh Vuong-Brender,Saurabh Taket al. Development (Cambridge, England), In press, 146 (24), pp.dev183780. ⟨10.1242/dev.183780⟩ Article dans une revue hal-02379395v3
Excitable RhoA dynamics drive pulsed contractions in the early C. elegans embryo Jonathan Michaux,François Robin,William Mcfadden,Edwin Munro Journal of Cell Biology, 2018, 217 (12), pp.4230-4252. ⟨10.1083/jcb.201806161⟩ Article dans une revue hal-03989022v1
Non-centrosomal epidermal microtubules act in parallel to LET-502/ROCK to promote C. elegans elongation Sophie Quintin,Shahoe Wang,Julien Pontabry,Ambre Bender,Francois Robinet al. Development (Cambridge, England), 2016, 143 (1), pp.160-173. ⟨10.1242/dev.126615⟩ Article dans une revue hal-01538537v1
Single-molecule analysis of cell surface dynamics in Caenorhabditis elegans embryos François Robin,William Mcfadden,Baixue Yao,Edwin Munro Nature Methods, 2014, 11 (6), pp.677-682. ⟨10.1038/nmeth.2928⟩ Article dans une revue hal-03988994v1
Creating 3D Digital Replicas of Ascidian Embryos from Stacks of Confocal Images François Robin,Delphine Dauga,Olivier Tassy,Daniel Sobral,Fabrice Daianet al. Cold Spring Harbor protocols, 2011, 2011 (10), pdb.prot065862. ⟨10.1101/pdb.prot065862⟩ Article dans une revue hal-03988953v1
Time-Lapse Imaging of Live Phallusia Embryos for Creating 3D Digital Replicas. François Robin,Delphine Dauga,Olivier Tassy,Daniel Sobral,Fabrice Daianet al. Cold Spring Harbor protocols, 2011, 2011 (10), pdb.prot065847. ⟨10.1101/pdb.prot065847⟩ Article dans une revue hal-03988971v1
Imaging of Fixed Ciona Embryos for Creating 3D Digital Replicas François Robin,Delphine Dauga,Olivier Tassy,Daniel Sobral,Fabrice Daianet al. Cold Spring Harbor protocols, 2011, 2011 (10), pdb.prot065854. ⟨10.1101/pdb.prot065854⟩ Article dans une revue hal-03988986v1
The ANISEED database: digital representation, formalization, and elucidation of a chordate developmental program. Olivier Tassy,Delphine Dauga,Fabrice Daian,Daniel Sobral,François Robinet al. Genome Research, 2010, 20 (10), pp.1459-1468. ⟨10.1101/gr.108175.110⟩ Article dans une revue hal-00586199v1
Sequential Activation of Apical and Basolateral Contractility Drives Ascidian Endoderm Invagination Kristin Sherrard,François Robin,Patrick Lemaire,Edwin Munro Current Biology, 2010, 20 (17), pp.1499-1510. ⟨10.1016/j.cub.2010.06.075⟩ Article dans une revue hal-03990370v1
A Multicassette Gateway Vector Set for High Throughput and Comparative Analyses in Ciona and Vertebrate Embryos Agnès Roure,Ute Rothbächer,François Robin,Eva Kalmar,Giustina Feroneet al. PLoS ONE, 2007, 2 (9), pp.e916. ⟨10.1371/journal.pone.0000916⟩ Article dans une revue hal-03988902v1
Cellular morphogenesis in ascidians: how to shape a simple tadpole Edwin Munro,Francois Robin,Patrick Lemaire Current Opinion in Genetics and Development, 2006, 16 (4), pp.399-405. ⟨10.1016/j.gde.2006.06.004⟩ Article dans une revue istex hal-01440654v1
Cellular morphogenesis in ascidians: how to shape a simple tadpole Edwin Munro,François Robin,Patrick Lemaire Current Opinion in Genetics and Development, 2006, 16 (4), pp.399-405. ⟨10.1016/j.gde.2006.06.004⟩ Article dans une revue istex hal-03990395v1