Frédéric Bigey Research Scientist, INRAE, France

Identifiants chercheurs

IdHAL :

frederic-bigey

ORCID :

0000-0002-6240-3038

ResearcherID :

http://www.researcherid.com/rid/F-2517-2010

Présentation

I am a research scientist specializing in yeast genomics and bioinformatics, with a focus on the comparative genomics of yeasts associated with food processes. My expertise lies in bioinformatics and computational biology, particularly in sequence analysis of industrial yeast genomes and in comparative genomics of yeasts from both technological and natural habitats.

In 2025, I was the first author of a comparative genomics study of the yeast Monosporozyma unispora (FEMS Yeast Research, DOI: 10.1093/femsyr/foaf016). This research highlighting their genetic diversity, adaptive traits, and relevance for both evolutionary studies and emerging biotechnological applications.

In 2024, I was the first author of a study on the genomic, genetic and phenotypic landscape of Candida anglica yeast population isolated from french PDO cheeses (Food Microbiology, DOI: 10.1016/j.fm.2024.104584). This work investigated how domestication and adaptation to this specific environment have shaped their genomic signatures, thereby informing our understanding of evolutionary processes.

In 2023, I was the first author of a comparative study of the oleagenous yeast Yarrowia lipolytica (Journal of Fungi, 9:76; DOI: 10.3390/jof9010076). With my colleagues I investigated 56 natural isolates and demonstrated that this species exhibits low genetic diversity, with a pan-genome closely resembling the core genome, suggesting a relatively recent evolutionary trajectory. Despite this, we observed substantial phenotypic diversity among strains, particularly regarding lipid metabolism.

In 2021, I was the first author of a study on the domestication of bakery yeast (Current Biology, 31:1–12; DOI: 10.1016/j.cub.2020.11.016). This work focused on Saccharomyces cerevisiae strains used in bread-making and revealed that domestication has been accompanied by dispersion, hybridization, and divergent selection processes, shaped differently by industrial and artisanal practices.

Earlier, in 2009, I co-authored the genome sequence analysis of the first wine yeast strain Saccharomyces cerevisiae EC1118 (PNAS, 106:16333–16338; DOI: 10.1073/pnas.0904673106), which uncovered unprecedented eukaryote-to-eukaryote horizontal gene transfer events. This study shed light on the genomic innovations that have contributed to the adaptation of S. cerevisiae wine strains to fermentation environments.

Collectively, my research integrates genomic sequencing, bioinformatics, and comparative evolutionary analyses to better understand yeast diversity, adaptation, and domestication, with direct implications for biotechnology and food fermentation processes.

Publications

Article dans une revue (45)

Insights into the genomic and phenotypic diversity of Monosporozyma unispora strains isolated from anthropic environments Frédéric Bigey,Xavière Menatong Tene,Marc Wessner,Hugo Devillers,Martine Pradalet al. FEMS Yeast Research, 2025, 25, pp.foaf016. ⟨10.1093/femsyr/foaf016⟩ Article dans une revue cea-05047166v1
Differential adaptation of the yeast Candida anglica to fermented food Frédéric Bigey,Xavière Menatong Tene,Marc Wessner,Martine Pradal,Jean-Marc Auryet al. Food Microbiology, 2024, 123, pp.104584. ⟨10.1016/j.fm.2024.104584⟩ Article dans une revue hal-04646352v1
Microbial Dynamics during labneh Ambaris Production in Earthenware Jars Reine Abi Khalil,Christel Couderc,Sophie Yvon,Delphine Sicard,Frédéric Bigeyet al. Foods, 2023, 12 (16), pp.3131. ⟨10.3390/foods12163131⟩ Article dans une revue hal-04197014v1
Insights into the Genomic and Phenotypic Landscape of the Oleaginous Yeast Yarrowia lipolytica Frédéric Bigey,Emilie Pasteur,Xymena Połomska,Stéphane Thomas,Anne-Marie A.-M. Crutz-Le Coqet al. Journal of Fungi, 2023, 9 (1), pp.76. ⟨10.3390/jof9010076⟩ Article dans une revue hal-03942758v1
Microbial communities and main features of labneh Ambaris, a traditional Lebanese fermented goat milk product Reine Abi Khalil,Sophie Yvon,Christel Couderc,Loubnah Belahcen,Gwenaelle Jardet al. Journal of Dairy Science, 2022, 106 (2), pp.868-883. ⟨10.3168/jds.2022-22275⟩ Article dans une revue hal-03922548v1
Artisanal Household Milk Pasteurization Is Not a Determining Factor in Structuring the Microbial Communities of Labneh Ambaris: A Pilot Study Reine Abi Khalil,Christel Couderc,Sophie Yvon,Gwenaelle Jard,Delphine Sicardet al. Foods, 2022, 11 (23), pp.3874. ⟨10.3390/foods11233874⟩ Article dans une revue hal-03880546v1
Evidence for Two Main Domestication Trajectories in Saccharomyces cerevisiae Linked to Distinct Bread-Making Processes Frédéric Bigey,Diego Segond,Anne Friedrich,Stephane Guezenec,Aurélie Bourgaiset al. Current Biology, 2021, 31, pp.722-732. ⟨10.1016/j.cub.2020.11.016⟩ Article dans une revue hal-03110131v1
The yeast mating-type switching endonuclease HO is a domesticated member of an unorthodox homing genetic element family Aisling Coughlan,Lisa Lombardi,Stephanie Braun-Galleani,Alexandre Ar Martos,Frederic Bigeyet al. eLife, 2020, 9, ⟨10.7554/eLife.55336⟩ Article dans une revue hal-02890164v1
Relief from nitrogen starvation entails quick unexpected down-regulation of glycolytic/lipid metabolism genes in enological Saccharomyces cerevisiae Catherine Tesniere,Chloé Bessiere,Martine Pradal,Isabelle Sanchez,Bruno Blondinet al. PLoS ONE, 2019, 14 (4), ⟨10.1371/journal.pone.0215870⟩ Article dans une revue hal-02126102v1
Genome sequence of Torulaspora microellipsoides CLIB 830T Virginie Galeote,Frederic Bigey,Hugo Devillers,Sylvie Dequin,Kenneth Wolfeet al. Genome Announcements, 2018, 6 (26), ⟨10.1128/genomeA.00615-18⟩ Article dans une revue hal-02623200v1
Relief from nitrogen starvation triggers transient destabilization of glycolytic mRNAs in Saccharomyces cerevisiae cells Catherine Tesniere,Martine Pradal,Chloé Bessiere,Isabelle Sanchez,Bruno Blondinet al. Molecular Biology of the Cell, 2018, 29 (4), pp.490-498. ⟨10.1091/mbc.E17-01-0061⟩ Article dans une revue hal-01837842v1
Adaptation of S. cerevisiae to Fermented Food Environments Reveals Remarkable Genome Plasticity and the Footprints of Domestication Jean-Luc Legras,Virginie Galeote,Frederic Bigey,Carole Camarasa,Souhir Marsitet al. Molecular Biology and Evolution, 2018, 35 (7), pp.1712-1727. ⟨10.1093/molbev/msy066⟩ Article dans une revue hal-01837856v1
Genomic signatures of adaptation to wine biological aging conditions in biofilm-forming flor yeasts Anna Lisa Coi,Frederic Bigey,Sandrine Mallet,Souhir Marsit,G. Zaraet al. Molecular Ecology, 2017, 26 (7), pp.2150-2166. ⟨10.1111/mec.14053⟩ Article dans une revue hal-01608516v1
Intrastrain genomic and phenotypic variability of the commercial Saccharomyces cerevisiae strain Zymaflore VL1 reveals microevolutionary adaptation to vineyard environments Ricardo Franco-Duarte,Frederic Bigey,Laura Carreto,Inês Mendes,Sylvie Dequinet al. FEMS Yeast Research, 2015, 15 (6), 13 p. ⟨10.1093/femsyr/fov063⟩ Article dans une revue hal-01837750v1
Natural yeast promoter variants reveal epistasis in the generation of transcriptional-mediated noise and its potential benefit in stressful conditions. Jian Liu,Helene Yken,Frederic Bigey,Sylvie Dequin,Jean Marie Françoiset al. Genome Biology and Evolution, 2015, 7 (4), pp.969-984. ⟨10.1093/gbe/evv047⟩ Article dans une revue hal-01190166v1
Une étude du besoin en azote des levures œnologiques révèle le rôle clé de la signalisation azote dans le contrôle de la vitesse de fermentation Claire Brice,Isabelle Sanchez,Catherine Tesniere,Frederic Bigey,Jean-Luc Legraset al. La revue des œnologues et des techniques vitivinicoles et œnologiques, 2015, 154, pp.21-24 Article dans une revue hal-01506449v1
Evolutionary advantage conferred by an eukaryote-to-eukaryote gene transfer event in wine yeasts Souhir Marsit,Adriana Mena,Frederic Bigey,Francois Xavier Sauvage,Arnaud Coulouxet al. Molecular Biology and Evolution, 2015, 32 (7), pp.1695-1707. ⟨10.1093/molbev/msv057⟩ Article dans une revue hal-01837744v1
New insights into the adaptation of yeast to anthropic environment using comparative genomics Jean-Luc Legras,Anna Lisa Coi,Frederic Bigey,Virginie Galeote,Souhir Marsitet al. Yeast, 2015, 32, pp.S89-S90. ⟨10.1002/yea.3091⟩ Article dans une revue hal-01837749v1
A genetic approach of wine yeast fermentation capacity in nitrogen-starvation reveals the key role of nitrogen signaling. Claire Brice,Isabelle Sanchez,Frederic Bigey,Jean-Luc Legras,Bruno Blondin BMC Genomics, 2014, 15 (1), pp.495. ⟨10.1186/1471-2164-15-495⟩ Article dans une revue hal-01189979v1
Genome sequence of the food spoilage Yeast Zygosaccharomyces bailii CLIB 213T. Virginie Galeote,Frédéric Bigey,Hugo Devillers,Cécile Neuvéglise,Sylvie Dequin Genome Announcements, 2013, 1 (4), ⟨10.1128/genomeA.00606-13⟩ Article dans une revue hal-01837764v1
Phenotypic landscape of Saccharomyces cerevisiae during wine fermentation: evidence for origin-dependent metabolic traits Carole Camarasa,Isabelle Sanchez,Pascale Brial,Frederic Bigey,Sylvie S. Dequin PLoS ONE, 2011, 6 (9), pp.e25147. ⟨10.1371/journal.pone.0025147⟩ Article dans une revue hal-02645675v1
Amplification of a Zygosaccharomyces bailii DNA Segment in Wine Yeast Genomes by Extrachromosomal Circular DNA Formation Virginie Galeote,Frederic Bigey,Emmanuelle Beyne,Maité Novo Molinero,Jean-Luc Legraset al. PLoS ONE, 2011, 6 (3), ⟨10.1371/journal.pone.0017872⟩ Article dans une revue hal-01222409v1
Deciphering the molecular basis of wine yeast fermentation traits using a combined genetic and genomic approach Chloé C. Ambroset,Maud Petit,Christian Brion,Isabelle Sanchez,Pierre Delobelet al. G3, 2011, 1, pp.263-281. ⟨10.1534/G3.111.000422⟩ Article dans une revue hal-01487358v1
Eukaryote-to-eukaryote gene transfer events revealed by the genome sequence of the wine yeast Saccharomyces cerevisiae EC1118 Maite Novo,Frederic Bigey,Emmanuelle Beyne,Virginie Galeote,Frédérick Gavoryet al. Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (38), pp.16333-16338. ⟨10.1073/pnas.0904673106⟩ Article dans une revue hal-02668729v1
Production of a recombinant carotenoid cleavage dioxygenase from grape and enzyme assay in water-miscible organic solvents Sandrine Mathieu,Frédéric Bigey,Jérôme Procureur,Nancy Terrier,Ziya Günata Biotechnology Letters, 2007, 29 (5), pp.837-841. ⟨10.1007/s10529-007-9315-8⟩ Article dans une revue istex hal-03763651v1
Overexpression and characterization of two human salivary proline rich proteins Christine Pascal,Frederic Bigey,Robert Ratomahenina,Helene Boze,Guy Moulinet al. Protein Expression and Purification, 2006, 47 (2), pp.524-532. ⟨10.1016/j.pep.2006.01.012⟩ Article dans une revue istex hal-02662210v1
A novel lipase / acyltransferase from the yeast Candida albicans: expression and characterisation of the recombinant enzyme Jean-Louis Roustan,Agustin Rascon Chu,Guy Moulin,Frederic Bigey Applied Microbiology and Biotechnology, 2005, 68 (2), pp.203-212. ⟨10.1007/s00253-005-1896-3⟩ Article dans une revue istex hal-02681391v1
A Carotenoid Cleavage Dioxygenase from Vitis vinifera L.: functional characterization and expression during grape berry development in relation to C13-norisoprenoid accumulation Sandrine Mathieu,Nancy Terrier,Jérôme Procureur,Frédéric Bigey,Ziya Günata Journal of Experimental Botany, 2005, 56 (420), pp.2721-2731. ⟨10.1093/jxb/eri265⟩ Article dans une revue hal-03763658v1
Overexpression of ovine leptin in Pichia pastoris : physiological yeast response to leptin production and characterization of the recombinant hormone C. Laborde,Patrick Chemardin,Frederic Bigey,Yves Combarnous,Gabrielle Moulinet al. Yeast, 2004, 21, pp.249-263. ⟨10.1002/yea.1073⟩ Article dans une revue hal-02675023v1
High-level expression of Candida parapsilosis lipase/acyltransferase in Pichia pastoris Laetitia Brunel,Virginie Neugnot,Laure Landucci,Helene Boze,Guy Moulinet al. Journal of Biotechnology, 2004, 111 (1), pp.41-50. ⟨10.1016/j.jbiotec.2004.03.007⟩ Article dans une revue istex hal-02166482v1
Identification of a triacylglycerol lipase gene family in Candida deformans: molecular cloning and functional expression Frederic Bigey,Karine Tuery,Daisy Bougard,Jean-Marc Nicaud,Guy Moulin Yeast, 2003, 20 (3), pp.233-248. ⟨10.1002/yea.958⟩ Article dans une revue hal-02165415v1
Transcriptional analysis of the nitrile-degrading operon from Rhodococcus sp. ACV2 and high level production of recombinant amidase with an Escherichia coli-T7 expression system Frederic Bigey,H. Chebrou,David Fournand,A. Arnaud Journal of Applied Microbiology, 1999, 86, pp.752-760 Article dans une revue hal-02689034v1
Acyl transfer activity of an amidase from Rhodococcus sp. strain R312: Formation of a wide range of hydroxamic acids David Fournand,Frederic Bigey,A. Arnaud Applied and Environmental Microbiology, 1998, 64 (8), pp.2844-2852 Article dans une revue hal-02690089v1
Biocatalyst improvement for the production of short-chain hydroxamic acids David Fournand,Frederic Bigey,Robert Ratomahenina,A. Arnaud,P. Galzy Enzyme and Microbial Technology, 1997, 20, pp.424-431 Article dans une revue hal-02697464v1
Spectrophotometric assay of aliphatic monohydroxamic acids and alpa-, bêta-, and gamma-aminohydroxamic acids in aqueous medium David Fournand,J.L. Pirat,Frederic Bigey,A. Arnaud,P. Galzy Analytica Chimica Acta, 1997, 353, pp.359-366 Article dans une revue hal-02698748v1
Amide metabolism: a putative ABC transporter in Rhodococcus sp. R312 H. Chebrou,Frederic Bigey,A. Arnaud,P. Galzy Gene, 1996, 182, pp.215-218 Article dans une revue hal-02691614v1
Study of the amidase signature group H. Chebrou,Frederic Bigey,A. Arnaud,P. Galzy BBA - Biochimica et Biophysica Acta, 1996, 1298, pp.285-293 Article dans une revue hal-02694915v1
Karyotype studies on different strains of Candida molischiana by pulsed-field gel electrophoresis Guilhem Janbon,R. Magnet,Frederic Bigey,A. Arnaud,P. Galzy Current Genetics, 1995, 28, pp.150-154 Article dans une revue hal-02712941v1
Sizing of the Rhodococcus sp. R312 genome by pulsed-field gel electrophoresis. Localization of genes involved in nitrile degradation Frederic Bigey,Guilhem Janbon,A. Arnaud,P. Galzy Antonie van Leeuwenhoek, 1995, 68, pp.173-179 Article dans une revue hal-02714288v1
Brevibacterium linens pBL33 and Rhodococcus rhodochrous pRC1 cryptic plasmids replicate in Rhodococcus sp. R312 (formerly Brevibacterium sp. R312) Frederic Bigey,B. Grossiord,C.K.N. Chan Kwo Chion,A. Arnaud,P. Galzy Gene, 1995, 154, pp.77-79 Article dans une revue hal-02710090v1
Application of high-performance liquid chromatography to the study of the biological transformation of adiponitrile J.L. Moreau,S. Azza,Frederic Bigey,A. Arnaud,P. Galzy Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 1994, 656, pp.197-202 Article dans une revue hal-02708542v1
The enzymatic production of adipic acid J.L. Moreau,Frederic Bigey,S. Azza,A. Arnaud,P. Galzy Biocatalysis and Agricultural Biotechnology, 1994, 10, pp.325-340 Article dans une revue hal-02713293v1
Cloning of the wide spectrum amidase gene from Brevibacterium sp. R312 by genetic complementation. Overexpression in Brevibacterium sp. and Escherichia coli S. Azza,Frederic Bigey,A. Arnaud,P. Galzy FEMS Microbiology Letters, 1994, 122, pp.129-136 Article dans une revue hal-02716101v1
Transformation of whole cells of Brevibacterium SP. R312, a nitrile hydratase producing strain C.N.K. Chan Kwo Chion,Frederic Bigey,A. Arnaud,P. Galzy Mededelingen van de Faculteit Landbouwwetenschappen Rijksuniversiteit Gent, 1992, 57 (4b), pp.2089-2091 Article dans une revue hal-02705497v1
The N-terminal amino acid sequences of Brevibacterium sp. R312 nitrile hydratase Robert Duran,C.K.N.C.K. Chion,F. Bigey,A. Arnaud,P. Galzy Applied Microbiology and Biotechnology, 1992, 32 (1), pp.13-19. ⟨10.1002/jobm.3620320104⟩ Article dans une revue istex hal-01841807v1

Communication dans un congrès (35)

Dici: a new Tc1/mariner transposon reshaping the genome of Diutina catenulata Frédéric Bigey,Cécile Neuveglise ISSY 38 "Yeast - the omni-tool", Adrianna Skoneczna; Zbigniew Lazar, Sep 2025, Warsaw, Poland Communication dans un congrès hal-05288044v1
Impacts de la domestication sur le génome des levures S. cerevisiae de vin et de pain Jean-Luc Legras,Virginie Galeote,Frédéric Bigey,Sylvie Dequin,Delphine Sicard 14. Journées Jean Chevaugeon - Rencontres de Phytopathologie - Mycologie, Jan 2024, Aussois, France Communication dans un congrès hal-04966875v1
Drivers of microbial communities dynamic in sourdough Thibault Nidelet,Jennifer Mata-Orozco,Stéphane Guezenec,Thérèse Marlin,Marie-Françoise Samsonet al. Séminaire sur le bilan des recherches sur le palmier à huile au Bénin, Société Française de Microbiologie, Oct 2022, Montpellier, France Communication dans un congrès hal-04237728v1
Mycotoxins throughout the life cycle of a wheat grain. A case study of organic farming with on-farm storage and processing Camille Vindras-Fouillet,Marie-Hélène Robin,François Brionnet,Frédéric Bigey,Delphine Sicardet al. 43. Mycotoxin Workshop, May 2022, Toulouse, France Communication dans un congrès hal-03727947v1
How different anthropogenic environments have shaped the genome of S. cerevisiae ? Virginie Galeote,Jean-Luc Legras,Frederic Bigey,Souhir Marsit,Carole Camarasaet al. 7. Conference on Physiology of Yeast and Filamentous Fungi, Jun 2019, Milan, Italy Communication dans un congrès hal-02461748v1
Horizontal gene transfer: one of the key mechanisms involved into the adaptation of yeast to their environment Virginie Galeote,Jean-Luc Legras,Frederic Bigey,Souhir Marsit,Carole Camarasaet al. ESF-EMBO Symposium, Comparative genomics of eukaryotic microbes: Genomes in flux, and flux between genomes, Oct 2019, Sant Feliu de Guíxols, Spain Communication dans un congrès hal-02461750v1
Horizontal Gene Transfer and Introgression: key mechanisms of adaptation of yeast to its ecological niches Virginie Galeote,Jean-Luc Legras,Souhir Marsit,Frederic Bigey,Carole Camarasaet al. 2. Joint Congress on Evolutionary Biology, Aug 2018, Montpellier, France Communication dans un congrès hal-01918074v1
Domesticated lineages of S. cerevisiae from fermented food environments present customized genome with selective footprints Jean-Luc Legras,Virginie Galeote,Frederic Bigey,Anna Lisa Coi,Souhir Marsitet al. 2. Joint Congress on Evolutionary Biology, 2018, Montpellier, France Communication dans un congrès hal-01918075v1
Horizontal Gene Transfer is a key mechanism permitting adaptation of S. cerevisiae to its ecological niches Virginie Galeote,Jean-Luc Legras,Frederic Bigey,Souhir Marsit,Carole Camarasaet al. Reunión anual conjunta genética y evolución, 2017, Puerto Varas, Chile Communication dans un congrès hal-01918076v1
Horizontal Gene Transfer is a key mechanism permitting adaptation of S. cerevisiae to its ecological niches Virginie Galeote,Jean-Luc Legras,Frederic Bigey,Souhir Marsit,Carole Camarasaet al. 21. Evolutionary Biology Meeting at Marseilles, 2017, Marseille, France Communication dans un congrès hal-01606234v1
Adaptation of Yeast to Anthropogenic Environments Using Comparative Genomics Jean-Luc Legras,Virginie Galeote,Anna Lisa Coi,Frederic Bigey,Souhir Marsitet al. 27. International Conference on Yeast Genetics and Molecular Biology (ICYGMB), Aug 2017, Prague, Czech Republic Communication dans un congrès hal-01608045v1
Exploring the adaptation of yeast to wine making environment using comparative genomics Jean-Luc Legras,Frederic Bigey,Virginie Galeote,Souhir Marsit,Arnaud Coulouxet al. SMBE Satellite meeting SMBEBA 2015 "Investigating biological adaptation with NGS: data and models", May 2015, Montpellier, France Communication dans un congrès hal-01837827v1
Adaptive Advantage Conferred by an Eukaryote-to-Eukaryote Gene Transfer Event in Wine Yeasts Souhir Marsit,Adriana Mena,Frederic Bigey,Francois Xavier Sauvage,Arnaud Coulouxet al. ESF-EMBO Symposium, Exploring the genomic complexity and diversity of eukaryotes, 2015, Sant Feliu de Guixols, Spain Communication dans un congrès hal-01606164v1
Adaptive Advantage of Horizontally Transferred Oligopeptide Transporters in Wine Yeasts Souhir Marsit,Frederic Bigey,Jean-Luc Legras,Virginie Galeote,Sylvie Dequin 27. International Conference on Yeast Genetics and Molecular Biology (ICYGMB), 2015, Trento, Italy Communication dans un congrès hal-01606657v1
The genetic basis of adaptation of flor strains : a comparative genome and genetic analysis Anna Lisa Coi,Jean-Luc Legras,Giacomo Zara,Frederic Bigey,Virginie Galeoteet al. 32. International Specialised Symposium on Yeasts-Yeast biodiversity and biotechnology in the twenty-first century, 2015, Perugia, Italy Communication dans un congrès hal-01606109v1
New insights into the adaptation of yeast to anthropic environment using comparative genomics Jean-Luc Legras,Anna Lisa Coi,Frederic Bigey,Virginie Galeote,Souhir Marsitet al. 27. International Conference on Yeast Genetics and Molecular Biology (ICYGMB), Sep 2015, Trentino, Italy. pp.1 Communication dans un congrès hal-01837824v1
New insights into adaptation of yeast to anthropic environment using comparative genomics Jean-Luc Legras,Anna Lisa Coi,Frederic Bigey,Virginie Galeote,Souhir Marsitet al. 32. International Specialized Symposium on Yeasts-Yeast Biodiversity and biotechnology in the twenty-first century, 2015, Perugia, Italy Communication dans un congrès hal-01606118v1
Improvement of wine yeast strains using adaptive evolution Axelle Cadière,Valentin Tilloy,Carole Camarasa,Frederic Bigey,Stephane Guezenecet al. ISSY 32, Sep 2015, Perugia, Italy Communication dans un congrès hal-01606246v1
Deciphering the adaptation of yeast to anthropic environment using comparative genomics Jean-Luc Legras,Anna Lisa Coi,Virginie Galeote,Frederic Bigey,Souhir Marsitet al. ESF-EMBO Symposium, Exploring the genomic complexity and diversity of eukaryotes, 2015, Sant Feliu de Guixols, Spain Communication dans un congrès hal-01606115v1
Adaptive role of horizontally transferred oligopeptide transporters in wine yeasts Souhir Marsit,Frederic Bigey,Jean-Luc Legras,Virginie Galeote,Sylvie Dequin 31. International Specialised Symposium on Yeast, 2014, Nova-Gorica/Vipava, Slovenia Communication dans un congrès hal-01604147v1
New insights into the adaptation of yeast to anthropic niches using comparative genomics. Focus on flor yeast. Jean-Luc Legras,Anna Lisa Coi,Frederic Bigey,Virginie Galeote,Souhir Marsitet al. EMBO Conference Series: Experimental Approaches to Evolution and Ecology, Oct 2014, Heidelberg, Germany. pp.1 Communication dans un congrès hal-01837724v1
Avantage adaptatif des transporteurs d’oligopeptides Fot1/2 acquis par transfert horizontal de gènes durant la fermentation alcoolique Souhir Marsit,Frederic Bigey,Jean-Luc Legras,Sylvie Dequin,Virginie Galeote Levures, Modèles & Outils – 11ème Rencontre des Levuristes Francophones, 2014, Bordeaux, France Communication dans un congrès hal-01606218v1
Adaptation des levures S. cerevisiae à des niches anthropiques à partir d’une approche de génomique des populations. Exemple de l’élevage en voile Jean-Luc Legras,Anna Lisa Coi,Virginie Galeote,Frederic Bigey,Souhir Marsitet al. Levures, Modèles & Outils – 11ème Rencontre des Levuristes Francophones, 2014, Bordeaux, France Communication dans un congrès hal-01606112v1
Evolutionnary and reverse engineering of commercially important metabolic traits in wine yeast Axelle Cadière,Valentin Tilloy,Carole Camarasa,Frederic Bigey,Stephane Guezenecet al. 31. International Specialised Symposium on Yeast, 2014, Nova Gorica/Vipava, Slovenia Communication dans un congrès hal-01605611v1
Adaptive role of horizontal gene transfers in wine yeasts: how to improve resource utilization to survive better Souhir Marsit,Frederic Bigey,Jean-Luc Legras,Virginie Galeote,Sylvie Dequin International Union of Microbiological Societies Congresses - IUMS2014, 2014, Montreal, Canada Communication dans un congrès hal-01603322v1
Characterization of genes involved in the adaptation of flor strains to biological ageing conditions of sherry wines Anna Lisa Coi,Jean-Luc Legras,Frederic Bigey,Virginie Galeote,Ilaria Mannazzuet al. 31. International Specialised Symposium on Yeast, 2014, Nova-Gorica/Vipava, Slovenia Communication dans un congrès hal-01606116v1
New insights into the adaptation of yeast to anthropic niches using comparative genomics. Focus on flor yeast genome Jean-Luc Legras,Anna Lisa Coi,Frederic Bigey,Virginie Galeote,Souhir Marsitet al. ESF-EMBO Comparative Genomics of Eukaryotic Microorganisms: Complexity Patterns in Eukaryotic Genomes, 2013, Sant Feliu de Guixols, Spain Communication dans un congrès hal-01606114v1
Adaptive role of horizontally transferred genes during wine fermentation. Souhir Marsit,Frederic Bigey,Jean-Luc Legras,Sylvie Dequin,Virginie Galeote ESF-EMBO Comparative Genomics of Eukaryotic Microorganisms: Complexity Patterns in Eukaryotic Genomes, 2013, Sant Feliu de Guixols, Spain Communication dans un congrès hal-01603320v1
Role of horizontally transfered genes in the adaptation of wine yeasts to their environnment Souhir Marsit,Frederic Bigey,Jean-Luc Legras,Sylvie Dequin,Virginie Galeote 5. Conference on Physiology of Yeast and Filamentous Fungi- PYFF5, 2013, Montpellier, France Communication dans un congrès hal-01607571v1
First insight into the adaptation of yeast to anthropic niches from genome sequence Jean-Luc Legras,Virginie Galeote,Frederic Bigey,Anna Lisa Coi,Souhir Marsitet al. 5. Conference on Physiology of Yeast and Filamentous Fungi, Institut National de Recherche Agronomique (INRA). UMR Sciences Pour l'Oenologie (1083)., 2013, Montpellier, France Communication dans un congrès hal-01606119v1
Characterization of genes involved in yeast adaptation to Sherry-like wines’ biological ageing identified by a genome based approach Anna Lisa Coi,Jean-Luc Legras,Frederic Bigey,Virginie Galeote,Marilena Budroniet al. ESFEMBO Comparative Genomics of Eukaryotic Microorganisms: Complexity Patterns in Eukaryotic Genomes, 2013, Sant Feliu de Guixols, Spain Communication dans un congrès hal-01606650v1
Genetic and phenotypic diversity of wine yeasts: Role of horizontal gene transfer Virginie Galeote,Frederic Bigey,Jean-Luc Legras,Souhir Marsit,Sylvie Dequin 13. International Congress on Yeasts (ICY 2012), Aug 2012, Madison, United States Communication dans un congrès hal-02805677v1
Diversity and adaptation of flor yeast : new data for an old question Jean-Luc Legras,Frederic Bigey,Anna Lisa Coi,Virginie Galeote,Claudine Charpentieret al. Journées des Microbiologistes de l’INRA 2012, Nov 2012, Avignon, France Communication dans un congrès hal-02804040v1
Diversity and adaptation of flor yeast : new data for an old question Jean-Luc Legras,Frederic Bigey,Anna Lisa Coi,Virginie Galeote,Claudine Charpentieret al. 13. International Congress on Yeasts (ICY 2012), 2012, Madison, United States Communication dans un congrès hal-02808760v1
Transformation of whole cells of Brevibacterium SP. R312, a nitrile hydratase producing strain C.N.K. Chan Kwo Chion,Frederic Bigey,A. Arnaud,P. Galzy 6. Forum for applied biotechnology, Sep 1992, Bruges, Belgium Communication dans un congrès hal-02843227v1

Poster de conférence (8)

Candida anglica, a yeast species newly found in cheese Frédéric Bigey,Xavière Menatong Tene,Marc Wessner,Martine Pradal,Jean-Marc Auryet al. WDS 2024, Oct 2024, Paris, France Poster de conférence hal-05288556v1
Yeast dispersion is the main driver of microbial community diversity in sourdough bread-making Lauriane Mietton,Jennifer Mata-Orozco,Hugo Devillers,Théo Guillerminet,Stéphane Guezenecet al. PYYF8 - 8. Conference on Physiology of Yeasts and Filamentous Fungi, Jun 2023, Cork, Ireland Poster de conférence hal-04237767v1
Genome and gene copy number variation in bakery yeast domestication Frédéric Bigey,Diego Segond,Anne Friedrich,Stephane Guezenec,Aurélie Bourgaiset al. EMBL Conference: Molecular Mechanisms in Evolution and Ecology, Sep 2020, Online, Germany Poster de conférence hal-02952117v1
Multiple genetic origins of Saccharomyces cerevisiae in bakery Frédéric Bigey,Diego Segond,Lucie Huyghe,Nicolas Agier,Aurélie Bourgaiset al. Comparative genomics of eukaryotic microbes: genomes in flux, and flux between genomes, Oct 2019, Sant Feliu de Guixols, Spain Poster de conférence hal-02950887v1
New insights into the adaptation of yeast to wine making using comparative genomics Jean-Luc Legras,Anna Lisa Coi,Frederic Bigey,Virginie Galeote,Souhir Marsitet al. 10. Symposium International d’Œnologie de Bordeaux, Œno2015, Jun 2015, Bordeaux, France. 2015 Poster de conférence hal-01606120v1
Adaptive advantage of oligopetide transporters acquired by horizontal transfer during wine fermentation Souhir Marsit,Frederic Bigey,Jean-Luc Legras,Sylvie Dequin,Virginie Galeote 10. Symposium International d’Œnologie de Bordeaux, Œno2015, Jun 2015, Bordeaux, France. 2015 Poster de conférence hal-01603326v1
Enhanced production of volatile esters by adaptively evolved Saccharomyces cerevisiae wine yeasts Sylvie Dequin,Axelle Cadière,Bastien Serrano,Carole Camarasa,Frederic Bigey 26. International Conference on Yeast Genetics and Molecular Biology, Aug 2013, Francfort-sur-le-Main, Germany. Wiley-Blackwell, Yeast, 30 (suppl.1), 2013, Yeast Poster de conférence hal-01837753v1
Stochastic gene expression, phenotypic variability and adaptation of budding yeast to environmental stresses Hélène Martin-Yken,Marlène Vuillemin,Frédéric Bigey,Sylvie Dequin,Jean-Marie Françoiset al. EMBO conference: Comparative Genomics Of Eukaryotic Microorganisms: Understanding The Complexity Of Diversity, Oct 2011, Sant Feliu de Guixols, Spain Poster de conférence hal-02952066v1

Brevet (1)

Lipase/acyltransferase Albrecht Weiss,Frédéric Bigey,Eric Dubreucq,Guy Moulin Germany, Patent n° : WO 03/006644 A2. 2003 Brevet hal-05329387v1