Frédéric Derbré

Publications

Article dans une revue (33)

Extreme physical inactivity alters iron metabolism: mechanisms and health issues for astronauts and bedridden patients Mathieu Horeau,Maelys Auffret,Olivier Loréal,Frédéric Derbré The Journal of Physiology, 2025, ⟨10.1113/jp289149⟩ Article dans une revue hal-05353916v1
Atypical gut microbial ecosystem from athletes with very high exercise capacity improves insulin sensitivity and muscle glycogen store in mice David Martin,Mathis Bonneau,Luz Orfila,Mathieu Horeau,Mathilde Hazonet al. Cell Reports, 2025, 44 (4), pp.115448. ⟨10.1016/j.celrep.2025.115448⟩ Article dans une revue hal-05033053v1
A conceptual framework for revealing rare bacterial species in the gut microbiome through guided data transformation: Beyond enterotypes David Martin,Pierre Houedry,Frederic Derbré,Valérie Monbet Methods in Ecology and Evolution, 2025, ⟨10.1111/2041-210x.70223⟩ Article dans une revue hal-05421483v1
Dry immersion rapidly disturbs iron metabolism in men and women: results from the VIVALDI studies Mathieu Horeau,Nastassia Navasiolava,Angelique van Ombergen,Marc-Antoine Custaud,Adrien Robinet al. NPJ Microgravity, 2024, 10 (1), pp.68. ⟨10.1038/s41526-024-00399-z⟩ Article dans une revue hal-04650054v1
The Yucatan minipig model: A new preclinical model of malnutrition in obese patients with acute or chronic diseases Annaëlle Couvert,Laurence Lacaze,Steve Touboulic,Sandrine Gautier,Sylvie Guerinet al. Clinical Nutrition, 2024, Clinical Nutrition (edinburgh, Scotland), 43 (2), pp.357-365. ⟨10.1016/j.clnu.2023.12.003⟩ Article dans une revue hal-04415280v1
Iron Metabolism Regulation in Females and Males Exposed to Simulated Microgravity: results from the Randomized Trial AGBRESA Mathieu Horeau,Martine Ropert,Edwin Mulder,Jens Tank,Petra Frings-Meuthenet al. The American Journal of Clinical Nutrition, 2022, 116 (5), pp.1430-1440. ⟨10.1093/ajcn/nqac205⟩ Article dans une revue hal-03777172v1
Oxidative and glycolytic skeletal muscles deploy protective mechanisms to avoid atrophy under pathophysiological iron overload David Martin,Kévin Nay,François Robin,Amélie Rebillard,Luz Orfilaet al. Journal of Cachexia, Sarcopenia and Muscle, 2022, 13 (2), pp.1250-1261. ⟨10.1002/jcsm.12897⟩ Article dans une revue hal-03564762v1
Does Physical Inactivity Induce Significant Changes in Human Gut Microbiota? New Answers Using the Dry Immersion Hypoactivity Model Maxence Jollet,Kevin Nay,Angèle Chopard,Marie-Pierre Bareille,Arnaud Becket al. Nutrients, 2021, 13 (11), ⟨10.3390/nu13113865⟩ Article dans une revue hal-03415988v1
Métabolisme du fer : impact de l'hypoactivité et mécanismes sous-jacents K. Nay,M. Horeau,Olivier Loréal,F. Derbré Cahiers de Nutrition et de Diététique, 2021, 56 (2), pp.131-140. ⟨10.1016/j.cnd.2021.01.002⟩ Article dans une revue hal-03225511v1
Simulated microgravity disturbs iron metabolism and distribution in humans: Lessons from dry immersion, an innovative ground-based human model Kevin Nay,Christelle Koechlin Ramonatxo,Rochdi Sarraj,Marie-Laure Island,Luz Orfilaet al. FASEB Journal, 2020, 34 (11), pp.14920-14929. ⟨10.1096/fj.202001199RR⟩ Article dans une revue hal-02946797v1
Ceruloplasmin deficiency does not induce macrophagic iron overload: lessons from a new rat model of hereditary aceruloplasminemia Moussa Kenawi,Emmanuel Rouger,Marie-Laure Island,Patricia Leroyer,François Robinet al. FASEB Journal, 2019, 44093 (12), pp.fj201901106R. ⟨10.1096/fj.201901106R⟩ Article dans une revue hal-02307161v1
Gut bacteria are critical for optimal muscle functiona potential link with glucose homeostasis Kevin Nay,Maxence Jollet,Benedicte Goustard,Narjes Baati,Barbara Vernuset al. AJP - Endocrinology and Metabolism, 2019, 317 (1), pp.E158-E171. ⟨10.1152/ajpendo.00521.2018⟩ Article dans une revue hal-02152871v1
Effects of intermittent muscle reconditioning on alterations of iron distribution and availability during simulated microgravity David J. R. Martin,Kevin Nay,Luz Orfila,Dany Saligaut,Moussa Kenawyet al. Acta Physiologica, 2019, 227 Article dans une revue hal-02393440v1
Skeletal muscle ceramides do not contribute to physical inactivity-induced insulin resistance Zéphyra Appriou,Kevin Nay,Nicolas Pierre,Dany Saligaut,Luz Lefeuvre-Orfilaet al. Applied Physiology, Nutrition, and Metabolism, 2019, 44 (11), pp.1180-1188. ⟨10.1139/apnm-2018-0850⟩ Article dans une revue hal-02087899v1
Allopurinol partially prevents disuse muscle atrophy in mice and humans Beatriz Ferrando,Mari Carmen Gomez-Cabrera,Andrea Salvador-Pascual,Carlos Puchades,Frédéric Derbréet al. Scientific Reports, 2018, 8 (1), pp.3549. ⟨10.1038/s41598-018-21552-1⟩ Article dans une revue hal-01744457v1
Simulated microgravity decreases circulating iron in rats: role of inflammation-induced hepcidin upregulation Thibault Cavey,Nicolas Pierre,Kevin Nay,Coralie Allain,Martine Ropertet al. Experimental Physiology, 2017, 102 (3), pp.291-298. ⟨10.1113/EP086188⟩ Article dans une revue hal-01483855v1
The diaphragm is better protected from oxidative stress than hindlimb skeletal muscle during CLP-induced sepsis Hélène Talarmin,Frédéric Derbré,Luz Lefeuvre-Orfila,Karelle Léon,Mickaël Droguetet al. Redox Report, 2017, 22 (5), pp.218-226. ⟨10.1080/13510002.2016.1223793⟩ Article dans une revue hal-01586183v1
Maintaining a regular physical activity aggravates intramuscular tumor growth in an orthotopic liposarcoma model Mohamad Assi,Frédéric Derbré,Luz Lefeuvre-Orfila,Dany Saligaut,Nathalie Stocket al. American Journal of Cancer Research, 2017, 7 (5), pp.1037--1053 Article dans une revue hal-01544192v1
The Oxygen Paradox, the French Paradox, and age-related diseases Joanna M. S. Davies,Josiane Cillard,Bertrand Friguet,Enrique Cadenas,Jean Cadetet al. GeroScience, 2017, 39 (5-6), pp.499-550. ⟨10.1007/s11357-017-0002-y⟩ Article dans une revue hal-01718093v1
Antioxidant supplementation accelerates cachexia development by promoting tumor growth in C26 tumor-bearing mice Mohamad Assi,Frédéric Derbré,Luz Lefeuvre-Orfila,Amélie Rébillard Free Radical Biology and Medicine, 2016, 91, pp.204-214. ⟨10.1016/j.freeradbiomed.2015.12.019⟩ Article dans une revue hal-01255843v1
From physical inactivity to immobilization: Dissecting the role of oxidative stress in skeletal muscle insulin resistance and atrophy Nicolas Pierre,Zéphyra Appriou,Arlette Gratas-Delamarche,Frédéric Derbré Free Radical Biology and Medicine, 2016, 98, pp.197-207. ⟨10.1016/j.freeradbiomed.2015.12.028⟩ Article dans une revue hal-01255823v1
Myriocin prevents muscle ceramide accumulation, but not muscle fiber atrophy during short-term mechanical unloading Erwann Salaun,Luz Lefeuvre-Orfila,Thibault Cavey,Brice Martin,Bruno Turlinet al. Journal of Applied Physiology, 2016, 120 (2), pp.178-187. ⟨10.1152/japplphysiol.00720.2015⟩ Article dans une revue hal-01231413v1
Single Muscle Immobilization Decreases Single-Fibre Myosin Heavy Chain Polymorphism: Possible Involvement of p38 and JNK MAP Kinases Frédéric Derbré,Mickaël Droguet,Karelle Léon,Samuel Troadec,Jean-Pierre Pennecet al. PLoS ONE, 2016, 11 (7), pp.e0158630. ⟨10.1371/journal.pone.0158630⟩ Article dans une revue hal-01397593v1
Physical inactivity, insulin resistanceand the oxidative-inflammatory loop Arlette Gratas-Delamarche,Frédéric Derbré,Sophie Vincent,Josiane Cillard Free Radic Res., 2014, 48 (1), pp.93-108. ⟨10.3109/10715762.2013.847528⟩ Article dans une revue hal-01159356v1
Mitochondrial fission and fusion in human diseases. F Sanchis-Gomar,Frédéric Derbré New England Journal of Medicine, 2014, 370 (11), pp.1073-4. ⟨10.1056/NEJMc1316254#SA1⟩ Article dans une revue hal-01159338v1
Inhibition of Xanthine Oxidase by Allopurinol Prevents Skeletal Muscle Atrophy: Role of p38 MAPKinase and E3 Ubiquitin Ligases Frédéric Derbré,B Ferrando,Mc Gómez-Cabrera,F Sanchis-Gomar,Ve Martinez-Belloet al. PLoS ONE, 2012, e46668, pp.e46668. ⟨10.1371/journal.pone.0046668⟩ Article dans une revue hal-01159428v1
Inactivity-induced oxidative stress: A central role in age-related sarcopenia? Frédéric Derbré,Arlette Gratas-Delamarche,M.C. Gomez-Cabrera,José Viña European Journal of Sport Science, 2012, 14 Suppl 1, pp.S98-108. ⟨10.1080/17461391.2011.654268⟩ Article dans une revue hal-01159426v1
Age associated low mitochondrial biogenesis may be explained by lack of response of PGC-1alpha to exercise training Frédéric Derbré,M C Gomez-Cabrera,a L Nascimento,F Sanchis-Gomar,V E Martinez-Belloet al. AGE, 2012, 34 (3), pp.669-679. ⟨10.1007/s11357-011-9264-y⟩ Article dans une revue hal-01159427v1
Rapid hemodilution induced by desmopressin after erythropoietin administration in humans F Sanchis Gomar,Ve Martinez Bello,Frédéric Derbré,E Garcia Lopez,R Garcia Valleset al. Journal of Human Sport and Exercise, 2011, 6 (2), pp.1-8. ⟨10.4100/jhse.2011.62.12⟩ Article dans une revue hal-01159461v1
Androgens responses to sprint exercise in young men Paul Delamarche,Arlette Delamarche,Frédéric Derbré,Maitel Botcazou,Serge Vincentet al. International Journal of Sports Medicine, 2010, 5 (31), pp.291-297 Article dans une revue halshs-00649696v1
Androgen Responses to Sprint Exercise in Young Men Frédéric Derbré,Serge Vincent,Maitel Botcazou,Christian Jacob,Paul Delamarcheet al. International Journal of Sports Medicine, 2010, 5 (31), pp.291-297 Article dans une revue halshs-00651190v1
Effects of sprint training and detraining on plasma volume variations induced by supramaximal exercise in adolescent boys Frédéric Derbré,Maitel Botcazou,Serge Vincent,Christian Jacob,Paul Delamarcheet al. Science & Sports, 2009, 24, pp.166-172 Article dans une revue halshs-00649850v1
Effets de l'entraînement de sprint et du désentraînement sur les variations du volume plasmatique induites par un test supramaximal chez des adolescents Frédéric Derbré,Maitel Botcazou,C. Jacob,V Sophie,A. Ben Abderrahmaneet al. Science & Sports, 2009, 24 (2), pp.166-172 Article dans une revue halshs-00651507v1

HDR (1)

Adaptations du muscle squelettique en condition physiopathologique. Mécanismes sous-jacents et répercussions sur le dialogue inter-organes dans les régulations métaboliques de l’organisme Frédéric Derbré Alimentation et Nutrition. Université Rennes 2, 2021 HDR tel-05079931v1

Poster de conférence (3)

Iron metabolism is differently regulated depending on muscle fiber phenotype David J. R. Martin,Kevin Nay,François Robin,Gevorg Ghukasyan,Suzanne Dufresneet al. 3. Congress of Physiology and Integrative Biology (CPBI) ; 86. Congress of French Physiological Society (SFP), Jun 2019, Montpellier, France. WILEY, Acta Physiologica, 227 (Supp 720), 2019, Abstracts of the 3rd Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP) Poster de conférence hal-02734839v1
Gut bacteria are critical for optimal muscle function: a potential link with glucose homeostasis Kevin Nay,Maxence Jollet,Benedicte Goustard,Barbara Vernus,Luz Lefeuvreet al. 3. Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP), Jun 2019, Montpellier, France. Wiley, Acta Physiologica, 227, 2019, Special Issue:Abstracts of the 3rd Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP) Poster de conférence hal-02735731v1
Effects of intermittent muscle reconditioning on alterations of iron distribution and availability during simulated microgravity David J. R. Martin,Kevin Nay,Luz Orfila,Dany Saligaut,Moussa Kenawyet al. 3. Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP), Jun 2019, Montpellier, France. John Wiley and Sons, Acta Physiologica, 227, 2019, Special Issue: Abstracts of the 3rd Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP) Poster de conférence hal-02734867v1

Communication dans un congrès (8)

Modulation of skeletal muscle function by gut Microbiota Dysbiosis and reseeding Kevin Nay,Maxence Jollet,Bénédicte Goustard,Barbara Vernus,Anne Bonnieuet al. European College of Sport Science, Jul 2018, Dublin, Ireland Communication dans un congrès hal-03753298v1
Modulation of skeletal muscle function by gut microbiota dysbiosis and reseeding Kevin Nay,Maxence Jollet,Bénédicte Goustard,Narjes Baati,Barbara Vernuset al. 5. World Congress on Targeting Microbiota, Oct 2017, Berlin, Germany Communication dans un congrès hal-03753288v1
OP17 - Natural antioxidants accelerate cachexia development in colon cancer Mohamad Assi,Frédéric Derbré,Luz Lefeuvre-Orfila,Amélie Rébillard SFRR-E/SNFS, 2015, Stuttgart, Germany. pp.S9--S10, ⟨10.1016/j.freeradbiomed.2015.07.044⟩ Communication dans un congrès istex hal-01198637v1
Effects of Galacto-oligosaccharides (GOS) on skeletal muscle atrophy, oxidative stress and inflammation in streptozotocin-diabetic rats. Beatriz Ferrando,Frédéric Derbré,Sophie Vincent,Carole Groussard,Luz Lefeuvre-Orfilaet al. 18th Annual Congress of the European College of Sport Sciences, Barcelone, Spain, 26-29 juin., 2013, Barcelone, Spain Communication dans un congrès hal-01159361v1
Effects of Galacto-oligosaccharides (GOS) and training on immune cells in streptozotocin-diabetic rats Sophie Vincent,Luz Lefeuvre-Orfila,Carole Groussard,Frédéric Derbré,Dany Saligautet al. 18th Annual Congress of the European College of Sport Sciences, Barcelone, Spain, 26-29 juin., 2013, Barcelone, Spain Communication dans un congrès hal-01159378v1
Coloration des fibres de réticuline sur tissu musculaire par la méthode de Gomori : intérêts pour l'étude de l'atrophie musculaire. Frédéric Derbré,P Bellaud,A Fautrel,Amélie Rébillard Congrès de l'Association Française d'Histotechnologie, 13-14 juin 2013, Rennes., 2013, Rennes, France Communication dans un congrès hal-01159364v1
Skeletal muscle regeration during aging and physical exercise : role of oxidative stress and myostatin Frédéric Derbré,Mari-Carmen Gomez-Cabrera,Ana Nascimiento,Vladimir Martinez-Bello,Fabian Sanchis-Gomaret al. 15th Annual Congress of the European College of Sport Science, 2010, Antalya, Turkey Communication dans un congrès hal-01159498v1
Bénéfices de l'allopurinol dans la prévention de l'atrophie musculaire induite par l'immobilisation Frédéric Derbré,B Ferrando,V Martinez-Bello,F Sanchis-Gomar,Garcia-Valles Ret al. Congrès P2T, 2010, Grenoble, France Communication dans un congrès hal-01159493v1

Thèse (1)

Etude des voies de signalisation impliquées dans la sarcopénie : rôle du stress oxydant et de l'inactivité physique Frédéric Derbré Education. Université Rennes 2, 2011. Français. ⟨NNT : 2011REN20036⟩ Thèse tel-00652764v1