Access content directly

Frédéric Flamant

95
Documents

Publications

Image document

Effect of in utero and lactational exposure to a thyroid hormone system disrupting chemical on mouse metabolome and brain transcriptome

Rikke Poulsen , Yanis Zekri , Romain Guyot , Frederic Flamant , Martin Hansen
Environmental Pollution, 2024, 340, pp.122783. ⟨10.1016/j.envpol.2023.122783⟩
Journal articles hal-04501084v1
Image document

The human OPA1 delTTAG mutation induces adult onset and progressive auditory neuropathy in mice

Corentin Affortit , Carolanne Coyat , Anissa Rym Saidia , Jean-Charles Ceccato , Majida Charif
Cellular and Molecular Life Sciences, 2024, 81, pp.80. ⟨10.1007/s00018-024-05115-4⟩
Journal articles hal-04501558v1
Image document

Thyroid hormone as a temporal switch in mouse development

Juan Ren , Frederic Flamant
European Thyroid Journal , 2023, 12 (2), pp.e220225. ⟨10.1530/etj-22-0225⟩
Journal articles hal-04222418v1
Image document

Thyroid hormone action during GABAergic neuron maturation: The quest for mechanisms

Sabine Richard , Juan Ren , Frederic Flamant
Frontiers in Endocrinology, 2023, 14, ⟨10.3389/fendo.2023.1256877⟩
Journal articles hal-04230619v1
Image document

Neuronal Blockade of Thyroid Hormone Signaling Increases Sensitivity to Diet-Induced Obesity in Adult Male Mice

Eva Rial-Pensado , Laurence Canaple , Romain Guyot , Christoffer Clemmensen , Joëlle Wiersema
Endocrinology, 2023, 164 (4), pp.bqad034. ⟨10.1210/endocr/bqad034⟩
Journal articles hal-04041371v1
Image document

Is periventricular heterotopia a useful endpoint for developmental thyroid hormone system disruption in mouse toxicity studies?

Louise Ramhøj , Romain Guyot , Terje Svingen , Andreas Kortenkamp , Frederic Flamant
Regulatory Toxicology and Pharmacology, 2023, 142, pp.105445. ⟨10.1016/j.yrtph.2023.105445⟩
Journal articles hal-04222380v1
Image document

Prenatal exposure to paraquat and nanoscaled TiO2 aerosols alters the gene expression of the developing brain

Quentin Hamdaoui , Yanis Zekri , Sabine Richard , Denise Aubert , Romain Guyot
Chemosphere, 2022, 287 (Pt 3), pp.132253. ⟨10.1016/j.chemosphere.2021.132253⟩
Journal articles hal-03403617v1

A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice

Corentin Affortit , Fabian Blanc , Jamal Nasr , Jean-Charles Ceccato , Suzy Markossian
Science Signaling, 2022, 15 (738), ⟨10.1126/scisignal.abj4583⟩
Journal articles hal-03746401v1
Image document

An Atlas of Thyroid Hormone Receptors’ Target Genes in Mouse Tissues

Yanis Zekri , Romain Guyot , Frederic Flamant
International Journal of Molecular Sciences, 2022, 23 (19), pp.11444. ⟨10.3390/ijms231911444⟩
Journal articles hal-03885312v1
Image document

Functional Definition of Thyroid Hormone Response Elements Based on a Synthetic STARR-seq Screen

Frédéric Flamant , Yanis Zekri , Romain Guyot
Endocrinology, 2022, 163 (8), pp.bqac084. ⟨10.1210/endocr/bqac084⟩
Journal articles hal-03746531v1

A CRISPR/Cas9-engineered avatar mouse model of monocarboxylate transporter 8 deficiency displays distinct neurological alterations

Víctor Valcárcel-Hernández , Marina Guillén-Yunta , Miranda Bueno-Arribas , Ana Montero-Pedrazuela , Carmen Grijota-Martínez
Neurobiology of Disease, 2022, 174, pp.105896. ⟨10.1016/j.nbd.2022.105896⟩
Journal articles hal-03887086v1
Image document

Brown adipocytes local response to thyroid hormone is required for adaptive thermogenesis in adult male mice

Yanis Zekri , Romain Guyot , Inés Garteizgogeascoa Suñer , Laurence Canaple , Amandine Gautier Stein
eLife, 2022, 11, pp.e81996. ⟨10.7554/elife.81996⟩
Journal articles hal-03958312v1

Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic

Yanis Zekri , Frederic Flamant , Karine Gauthier
Cells, 2021, 10 (6), pp.1327. ⟨10.3390/cells10061327⟩
Journal articles hal-03278371v1

Thyroid hormone and mammalian tissue regeneration

Frederic Flamant
Annales d'Endocrinologie = Annals of Endocrinology, 2021, 82 (3-4), pp.158-160. ⟨10.1016/j.ando.2020.02.002⟩
Journal articles hal-03285023v1
Image document

In vitro assessment of pesticides capacity to act as agonists/antagonists of the thyroid hormone nuclear receptors

Yanis Zekri , Laure Dall Agnol , Frederic Flamant , Romain Guyot
iScience, 2021, 24 (9), pp.1-21. ⟨10.1016/j.isci.2021.102957⟩
Journal articles hal-03520452v1
Image document

Metrological Characterization of an Aerosol Exposure Chamber to Explore the Inhalation Effects of the Combination of Paraquat and TiO2 Nano-objects

Quentin Hamdaoui , A. Bencsik , Frederic Flamant , Simon Delcour , Tatiana Macé
Aerosol and Air Quality Research, 2021, 21 (8), pp.200626. ⟨10.4209/aaqr.200626⟩
Journal articles hal-03416520v1

A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons

Sabine Richard , Romain Guyot , Martin Rey-Millet , Margaux Prieux , Suzy S. Markossian
iScience, 2020, 23 (3), pp.100899. ⟨10.1016/j.isci.2020.100899⟩
Journal articles hal-03254963v1
Image document

Thyroid hormone receptor α in skeletal muscle is essential for T3‐mediated increase in energy expenditure

Trine S Nicolaisen , Anders B Klein , Oksana Dmytriyeva , Jens Lund , Lars R Ingerslev
FASEB Journal, 2020, 34 (11), pp.15480-15491. ⟨10.1096/fj.202001258RR⟩
Journal articles hal-02996920v1
Image document

ERGO: Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters

Henrik Holbech , Peter Matthiessen , Martin Hansen , Gerrit Schuurmann , Dries Knapen
International Journal of Molecular Sciences, 2020, 21 (8), pp.2954. ⟨10.3390/ijms21082954⟩
Journal articles hal-02904035v1

Two Novel Cases of Resistance to Thyroid Hormone Due to THRA Mutation

Albane Le Maire , Natacha Bouhours-Nouet , Jessica Soamalala , Delphine Mirebeau-Prunier , Matteo Paloni
Thyroid, 2020, 30 (8), pp.1217-1221. ⟨10.1089/thy.2019.0602⟩
Journal articles hal-03042980v1
Image document

PRMT1 Is Critical for the Transcriptional Activity and the Stability of the Progesterone Receptor.

Lucie Malbeteau , Coralie Poulard , Cécile Languilaire , Ivan Mikaelian , Frederic Flamant
iScience, 2020, 23 (6), pp.101236. ⟨10.1016/j.isci.2020.101236⟩
Journal articles hal-03019840v1

Evidence for hormonal control of heart regenerative capacity during endothermy acquisition

Kentaro Hirose , Alexander Payumo , Stephen Cutie , Alison Hoang , Hao Zhang
Science, 2019, pp.eaar2038. ⟨10.1126/science.aar2038⟩
Journal articles hal-02983719v1

Metabolomic Profiling of Body Fluids in Mouse Models Demonstrates that Nuclear Magnetic Resonance Is a Putative Diagnostic Tool for the Presence of Thyroid Hormone Receptor α1 Mutations

Houda Boumaza , Suzy S. Markossian , Baptiste Busi , Gilles J.P. Rautureau , Karine Gauthier
Thyroid, 2019, 29 (9), pp.1327-1335. ⟨10.1089/thy.2018.0730⟩
Journal articles hal-02983685v1

New Case of Thyroid Hormone Resistance α Caused by a Mutation of THRA/TRα1

Hui Sun , Haiying Wu , Rongrong Xie , Fengyun Wang , Ting Chen
Journal of the Endocrine Society, 2019, 3 (3), pp.665-669. ⟨10.1210/js.2019-00011⟩
Journal articles hal-02983728v1
Image document

Pesticides, perturbateurs endocriniens de la glande thyroïde ?

Frederic Flamant
Les cahiers de la Recherche : Santé, Environnement, Travail, 2019, Les perturbateurs endocriniens, 13, pp.23-25
Journal articles anses-02445614v1

Two Protocols to Study the Interactions of Thyroid Hormone Receptors with Other Proteins and Chromatin

Henrik Holbech , Peter Matthiessen , Martin Hansen , Gerrit Schüürmann , Dries Knapen
Frontiers in Endocrinology, 2018, 1801 (3), pp.9-16. ⟨10.1007/978-1-4939-7902-8_2⟩
Journal articles hal-03278376v1
Image document

Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing

Marie Teixeira , Bénédicte Py , Christophe Bosc , Daphne Laubreton , Marie-Jo Moutin
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-017-18826-5⟩
Journal articles hal-02345809v1
Image document

Regulation of T3 Availability in the Developing Brain: The Mouse Genetics Contribution

Sabine Richard , Frederic Flamant
Frontiers in Endocrinology, 2018, 9, 11 p. ⟨10.3389/fendo.2018.00265⟩
Journal articles hal-02621572v1

Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing

Marie Teixeira , Bénédicte F. Py , Christophe Bosc , Daphné Laubreton , Marie-Jo Moutin
Scientific Reports, 2018, 8 (1), pp.4679. ⟨10.1038/s41598-018-22724-9⟩
Journal articles hal-01908850v1

CRISPR/Cas9 Editing of the Mouse Thra Gene Produces Models with Variable Resistance to Thyroid Hormone

Suzy S. Markossian , Romain Guyot , Sabine Richard , Marie Teixeira , Nadine Aguilera
Thyroid, 2018, 28 (1), pp.139-150. ⟨10.1089/thy.2017.0389⟩
Journal articles hal-03278383v1

Genetic Investigation of Thyroid Hormone Receptor Function in the Developing and Adult Brain

Frederic Flamant , Karine Gauthier , Sabine Richard
Current Topics in Developmental Biology, 2017, 125, pp.303-335. ⟨10.1016/bs.ctdb.2017.01.001⟩
Journal articles hal-03278392v1

Neuronal expression of a thyroid hormone receptor α mutation alters mouse behaviour

S. Richard , N. Aguilera , M. Thévenet , O. Dkhissi-Benyahya , Frederic Flamant
Behavioural Brain Research, 2017, 321, pp.18-27. ⟨10.1016/j.bbr.2016.12.025⟩
Journal articles hal-03278396v1

Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature

Frederic Flamant , Sheue-Yann Cheng , Anthony Hollenberg , Lars Moeller , Jacques Samarut
Endocrinology, 2017, 158 (7), pp.2052-2057. ⟨10.1210/en.2017-00250⟩
Journal articles hal-03278395v1

Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin

Wenyue Guan , Romain Guyot , Jacques Samarut , Frederic Flamant , Jiemin Wong
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (31), pp.8229-8234. ⟨10.1073/pnas.1702192114⟩
Journal articles hal-03278385v1
Image document

Thyroid Hormone signaling in the mouse retina

Patrick Arbogast , Frederic Flamant , Pierre Godement , Martin Glösmann , Leo Peichl
PLoS ONE, 2016, 11 (12), 20 p. ⟨10.1371/journal.pone.0168003⟩
Journal articles hal-01602508v1
Image document

Futures Challenges in Thyroid Hormone Signaling Research

Frederic Flamant
Frontiers in Endocrinology, 2016, 7, ⟨10.3389/fendo.2016.00058⟩
Journal articles hal-02635655v1

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

Brian Finan , Christoffer Clemmensen , Zhimeng Zhu , Kerstin Stemmer , Karine Gauthier
Cell, 2016, 167 (3), pp.843-857.e14. ⟨10.1016/j.cell.2016.09.014⟩
Journal articles hal-03278397v1

CRISPR/Cas9: a breakthrough in generating mouse models for endocrinologists

Suzy S. Markossian , Frederic Flamant
Journal of Molecular Endocrinology, 2016, 57 (2), pp.R81-R92. ⟨10.1530/JME-15-0305⟩
Journal articles hal-03278399v1

A Novel Mutation in THRA Gene Associated With an Atypical Phenotype of Resistance to Thyroid Hormone

Stéphanie Espiard , Frédérique Savagner , Frederic Flamant , Virginie Vlaeminck-Guillem , Romain Guyot
Journal of Clinical Endocrinology and Metabolism, 2015, 100 (8), pp.2841-2848. ⟨10.1210/jc.2015-1120⟩
Journal articles hal-02952401v1

Editorial: “Thyroid Hormone in Brain and Brain Cells”

Frederic Flamant , Noriyuki Koibuchi , Juan Bernal
Frontiers in Endocrinology, 2015, 6, pp.99. ⟨10.3389/fendo.2015.00099⟩
Journal articles hal-03278404v1

TRα receptor mutations extend the spectrum of syndromes of reduced sensitivity to thyroid hormone

Virginie Vlaeminck-Guillem , Stéphanie Espiard , Frederic Flamant , Jean-Louis Wémeau
La Presse Médicale, 2015, 44 (11), pp.1103-1112. ⟨10.1016/j.lpm.2015.07.022⟩
Journal articles hal-03278401v1

A temporary compendium of thyroid hormone target genes in brain

Fabrice Chatonnet , Frederic Flamant , Beatriz Morte
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2015, 1849 (2), pp.122-129. ⟨10.1016/j.bbagrm.2014.05.023⟩
Journal articles hal-02164764v1

Nongenomic, TRβ-Dependent, Thyroid Hormone Response Gets Genetic Support

Fabrice Chatonnet , Gabriel Livera , Betty Fumel , Sophie Fouchécourt , Karine Gauthier
Endocrinology, 2014, 155 (9), pp.3206-3209. ⟨10.1210/en.2014-1597⟩
Journal articles hal-03278412v1

Autonomous functions of murine thyroid hormone receptor TRα and TRβ in cochlear hair cells

Juliane Dettling , Christoph Franz , Ulrike Zimmermann , Sze Chim Lee , Andreas Bress
Molecular and Cellular Endocrinology, 2014, 382 (1), pp.26-37. ⟨10.1016/j.mce.2013.08.025⟩
Journal articles hal-03278424v1

Minireview: Deciphering Direct and Indirect Influence of Thyroid Hormone With Mouse Genetics

N. Aguilera , M. Thévenet , O. Dkhissi-Benyahya , Frédéric Picou , Teddy Fauquier
Molecular Endocrinology, 2014, 28 (4), pp.429-441. ⟨10.1210/me.2013-1414⟩
Journal articles hal-03278418v1

Purkinje cells and Bergmann glia are primary targets of the TRα1 thyroid hormone receptor during mouse cerebellum postnatal development.

Teddy Fauquier , Fabrice Chatonnet , Frédéric Picou , Sabine Richard , Nicolas Fossat
Development (Cambridge, England), 2014, 141 (1), pp.166-75. ⟨10.1242/dev.103226⟩
Journal articles hal-00968730v1

Direct and indirect consequences on gene expression of a thyroid hormone receptor alpha 1 mutation restricted to Sertoli cells

Fabrice Chatonnet , Gabriel Livera , Betty Fumel , Sophie Fouchécourt , Frederic Flamant
Molecular Reproduction and Development, 2014, 81 (12), pp.1159 - 1166. ⟨10.1002/mrd.22437⟩
Journal articles hal-01130502v1
Image document

Chondrocytes Play a Major Role in the Stimulation of Bone Growth by Thyroid Hormone

Clémence Desjardin , Cyril Charles , Catherine Benoist-Lasselin , Julie Riviere , Maïlys Gilles
Endocrinology, 2014, 155 (8), pp.3123-3135. ⟨10.1210/en.2014-1109⟩
Journal articles hal-01193997v1

Toxicogenomic analysis of the ability of brominated flame retardants TBBPA and BDE-209 to disrupt thyroid hormone signaling in neural cells

Romain Guyot , Fabrice Chatonnet , Benjamin Gillet , Sandrine Hughes , Frederic Flamant
Toxicology, 2014, 325, pp.125-132. ⟨10.1016/j.tox.2014.08.007⟩
Journal articles hal-03278405v1

The Targeted Inactivation of TRβ Gene in Thyroid Follicular Cells Suggests a New Mechanism of Regulation of Thyroid Hormone Production

Samia Selmi-Ruby , Lamia Bouazza , Maria-Jesus Obregon , Aude Conscience , Frederic Flamant
Endocrinology, 2014, 155 (2), pp.635-646. ⟨10.1210/en.2013-1435⟩
Journal articles hal-03278422v1

[Thyroid hormone T3 triggers the developmental loss of axonal regenerative capacity]

Hasan X. Avci , Frederic Flamant , Isabelle Dusart
Médecine/Sciences, 2013, 29 (3), pp.245--247. ⟨10.1051/medsci/2013293005⟩
Journal articles hal-01543628v1

Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells

Hasan Avci , Clement Lebrun , Rosine Wehrle , Mohamed Doulazmi , Marie-Pierre Morel
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (8), pp.E766-E775. ⟨10.1073/pnas.1210626110⟩
Journal articles hal-03278425v1
Image document

Genome-Wide Search Reveals the Existence of a Limited Number of Thyroid Hormone Receptor Alpha Target Genes in Cerebellar Neurons

Fabrice Chatonnet , Romain Guyot , Frédéric Picou , Maria Bondesson , Frederic Flamant
PLoS ONE, 2012, 7 (5), pp.e30703. ⟨10.1371/journal.pone.0030703⟩
Journal articles hal-02164760v1
Image document

Profound morphological and functional changes of rodent Purkinje cells between the first and the second postnatal weeks: a metamorphosis?

Isabelle Dusart , Frederic Flamant
Frontiers in Neuroanatomy, 2012, 6, pp.11. ⟨10.3389/fnana.2012.00011⟩
Journal articles hal-01543632v1

Thyroid hormone limits postnatal Sertoli cell proliferation in vivo by activation of its alpha1 isoform receptor (TRalpha1) present in these cells and by regulation of Cdk4/JunD/c-myc mRNA levels in mice

Betty Fumel , Marie-Justine Guerquin , Gabriel Livera , Christophe Staub , Michèle Magistrini
Biology of Reproduction, 2012, 87 (1), pp.1-9. ⟨10.1095/biolreprod.111.098418⟩
Journal articles hal-01129659v1

Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor alpha 1 and kruppel-like factor 9 in Purkinje cells

Hasan X. Avci , Clement Lebrun , Rosine Wehrle , Mohamed Doulazmi , Fabrice Chatonnet
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (35), pp.14206-14211. ⟨10.1073/pnas.1119853109⟩
Journal articles hal-01545809v1

Hormone thyroïdienne et développement du cervelet : effets directs ou indirects ?

Fabrice Chatonnet , Teddy Fauquier , Frederic Picou , Romain Guyot , Frederic Flamant
Annales d'Endocrinologie = Annals of Endocrinology, 2011, 72 (2), pp.99-102. ⟨10.1016/j.ando.2011.03.012⟩
Journal articles hal-02164736v1
Image document

Otx2 Gene Deletion in Adult Mouse Retina Induces Rapid RPE Dystrophy and Slow Photoreceptor Degeneration.

Francis Béby , Michael Housset , Nicolas Fossat , Coralie Le Greneur , Frederic Flamant
PLoS ONE, 2010, 5 (7), pp.e11673. ⟨10.1371/journal.pone.0011673⟩
Journal articles hal-00506174v1

A combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum.

Laure Quignodon , Carmen Grijota-Martinez , Emmanuel Compe , Romain Guyot , Nathalie Allioli
Journal of Molecular Endocrinology, 2007, 39 (1), pp.17-28. ⟨10.1677/JME-06-0054⟩
Journal articles hal-00206218v1

Peripheral circulation of the prion infectious agent in transgenic mice expressing the ovine prion protein gene in neurons only

C. Crozet , S. Lezmi , Frederic Flamant , J. Samarut , T. Baron
Journal of Infectious Diseases, 2007, 195 (7), pp.997-1006. ⟨10.1086/512085⟩
Journal articles hal-00180826v1
Image document

Modeling the role of mid-wavelength cones in circadian responses to light.

Ouria Dkhissi-Benyahya , Claude Gronfier , Wena de Vanssay , Frederic Flamant , Howard M. Cooper
Neuron, 2007, 53 (5), pp.677-87. ⟨10.1016/j.neuron.2007.02.005⟩
Journal articles inserm-00135926v1

Both thyroid hormone receptor (TR)beta1 and TRbeta2 isoforms contribute to the regulation of hypothalamic Thyrotropin-releasing hormone

S.M. Dupré , H. Guissouma , Frederic Flamant , I. Seugnet , T.S. Scanlan
Endocrinology, 2004, 145 (5), pp.2337-2345. ⟨10.1210/en.2003-1209⟩
Journal articles hal-02675694v1

Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life

W. Mai , M.F. Janier , Nathalie Allioli , Laure Quignodon , T. Chuzel
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (28), pp.10332-10337
Journal articles hal-02677765v1

The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification

E. Bonnafe , M. Touka , A. Aitlounis , D. Baas , E. Barras
Molecular and Cellular Biology, 2004, 24 (10), pp.4417-4427
Journal articles hal-02679672v1

Thyroid hormone signaling is highly heterogeneous during pre- and postnatal brain development

Laure Quignodon , C. Legrand , Nathalie Allioli , A. Guadano-Ferraz , Joaquin Bernal
Journal of Molecular Endocrinology, 2004, 33, pp.467-476
Journal articles hal-02672363v1

Thyroid hormone receptors : lessons from knockout and knock-in mutant mice

Frederic Flamant , Jacques Samarut
Trends in Endocrinology and Metabolism = Trends in Endocrinology & Metabolism , 2003, 14 (2), pp.85-90
Journal articles hal-02670632v1

Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice

P.M. Yen , Xu Ping Feng , Frederic Flamant , Y. Chen , R.L. Walker
EMBO Reports, 2003, 4 (6), pp.581-587
Journal articles hal-02676180v1

Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum

A.L. Poguet , C. Legrand , Xu Ping Feng , P.M. Yen , P. Meltzer
Developmental Biology, 2003, 254, pp.188-199
Journal articles hal-02671535v1

Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors

D. Baas , C. Legrand , Jacques Samarut , Frederic Flamant
Proceedings of the National Academy of Sciences of the United States of America, 2002, 99 (5), pp.2907-2911. ⟨10.1073/pnas.052482299⟩
Journal articles hal-02678333v1

Congenital hypothyroid Pax8-/- mutant mice can be rescued by inactivating the TRalpha gene

Frederic Flamant , A.L. Poguet , Michelina Plateroti , O. Chanssade , K. Gauthier
Molecular Endocrinology -Baltimore-, 2002, 16 (1), pp.24-32
Journal articles hal-02679582v1

Null mutant mice for thyroid hormone receptors. In Thyroid hormone receptors.

Karine Gauthier , Denise Aubert , Olivier Chassande , Frederic Flamant , Jacques Samarut
Methods in molecular medicine, 2002, 22, pp.13-29
Journal articles hal-00023831v1

Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine PrP gene

Carole Crozet , Frederic Flamant , A. Bencsik , Denise Aubert , Jacques Samarut
Journal of Virology, 2001, 75 (11), pp.5328-5334
Journal articles hal-02672143v1

Florid Plaque in ovine PrP transgenic mice infected with an experimental ovine BSE.

C. Crozet , A. Bencsik , Frederic Flamant , S. Lezmi , Jacques Samarut
EMBO Reports, 2001, 21 (10), pp.952-956. ⟨10.1093/embo-reports/kve204⟩
Journal articles hal-00023828v1

Eukaryotic conditional expression system

T. Sourisseau , Y. Le Dréan , G. Salbert , Frederic Flamant , D. Michel
Biotechniques, 1999, 27, pp.106-110
Journal articles hal-02688895v1

A novel growth -factor-dependent myeloid cell line derived from mouse bone marrow cells contains progenitors endowed with high proliferative potential

V. Revol , I. Tsuboi , Frederic Flamant , Jacques Samarut , J.P. Blanchet
Experimental Hematology, 1999, 27 (1), pp.88-98
Journal articles hal-02683916v1

Thyroid hormone receptor knockouts : their contribution to our understanding of thyroid hormone resistance

Olivier Chassande , Frederic Flamant , Jacques Samarut
Current Opinion in Endocrinology and Diabetes, 1999, 6, pp.293-300
Journal articles hal-02693744v1

Involvement of thyroid hormone and its alpha receptor in avian neurulation

Frederic Flamant , Jacques Samarut
Developmental Biology, 1998, 197, pp.1-11
Journal articles hal-02683768v1

Identification of transcripts initiated from an internal promoter in the c-erbA-alpha locus that encode inhibitors of retinoic acid receptor-alpha and triiodothyronine receptor activities

Olivier Chassande , A. Fraichard , K. Gauthier , Frederic Flamant , C. Legrand
Molecular Endocrinology -Baltimore-, 1997, 11 (9), pp.1278-1290
Journal articles hal-02695326v1

The osteoclast generation : an in vitro and in vivo study with a genetically labelled avian monocytic cell line

F. Solari , Frederic Flamant , Yan Cherel , Monique Wyers , Pierre Jurdic
Journal of Cell Science, 1996, 109, pp.1203-1213
Journal articles hal-02691819v1

Replication-competent and -defective retrovirus vectors for oncogenic studies

Jacques Samarut , Frederic Flamant , J.M. Heard
Methods in Enzymology, 1995, 254, pp.206-228
Journal articles hal-02706921v1

Vectors derived from avian leucosis and sarcoma viruses

Frederic Flamant , Cosset François-Loïc , Jacques Samarut
Journal of Molecular Medicine, 1995, 73, pp.181-187
Journal articles hal-02704566v1

Virofection : a one-step procedure for using replication-defective retrovirus vectors

Frederic Flamant , Jacques Samarut
Virology, 1995, 211, pp.234-240
Journal articles hal-02705128v1

Virofection: a new procedure to achieve stable expression of genes transferred into early embryos

Frederic Flamant , Barbara Demeneix , C. Benoist , Suzy Markossian-Belin , Jacques Samarut
International Journal of Developmental Biology, 1994, 38, pp.751-757
Journal articles hal-02699936v1

Use of helper cells with two host ranges to generate high-titer retroviral vectors

Cosset François-Loïc , A. Girod , Frederic Flamant , A. Drynda , C. Ronfort
Virology, 1993, 193, pp.385-395
Journal articles hal-02703909v1

Importance of 3' non-coding sequences for efficient retrovirus-mediated gene transfer in avian cells revealed by self-inactivating vectors

Frederic Flamant , Denise Aubert , C. Legrand , Cosset François-Loïc , Jacques Samarut
Journal of General Virology, 1993, 74, pp.39-46
Journal articles hal-02699527v1

Identifying genes involved in the variability of genetic fatness in the growing chicken

M. Douaire , N. Le Fur , C. El Khadir-Mounier , Paul Langlois , Frederic Flamant
Poultry Science, 1992, 71, pp.1911-1920
Journal articles hal-02699766v1

Packaging cells for avian leukosis virus-based vectors with various host ranges

Cosset François-Loïc , C. Ronfort , R.M. Molina , Frederic Flamant , A. Drynda
Journal of Virology, 1992, 66 (9), pp.5671-5676
Journal articles hal-02703488v1

Self-inactivating avian leukosis derived retroviral vectors for gene transfer and stable expression into cultured avian cells

Denise Aubert , Camille Bagnis , Frederic Flamant , M. Garcia , Jacques Samarut
Virology, 1991, 10, pp.71-76
Journal articles hal-02708464v1

ApoVLDLII gene transcription in immature cockerels without estradiol stimulation.

M. Douaire , Paul Langlois , Frederic Flamant , J. Mallard
Comparative Biochemistry and Physiology, 1990, 97B (1), pp.55-57
Journal articles hal-02699564v1

In vitro synthesis of infectious retroviral RNA

Frederic Flamant , J Sorge
Journal of Virology, 1988, 62 (5), pp.1827-1831. ⟨10.1128/JVI.62.5.1827-1831.1988⟩
Journal articles hal-03278437v1
Image document

CONSTRUCTION ET UTILISATION DE VECTEURS DÉRIVÉS DU VIRUS DE L'ÉRYTHROBLASTOSE AVIAIRE POUR LE TRANSFERT DE GÈNES CHEZ LE POULET

Frederic Flamant , Benchaibi M , Thoraval P , Chambonnet F , Savatier P
Annales de Recherches Vétérinaires, 1988, 19 (1), pp.85-86
Journal articles hal-00901808v1

An embryonic DNA-binding protein specific for the promoter of the retrovirus long terminal repeat

Frederic Flamant , C Gurin , J Sorge
Molecular and Cellular Biology, 1987, 7 (10), pp.3548-3553. ⟨10.1128/mcb.7.10.3548-3553.1987⟩
Journal articles hal-03278438v1

Tissue specificity of retrovirus expression in inoculated avian embryos revealed by in situ hybridization to whole-body section.

Frederic Flamant , D. Leguellec , Ghislain Verdier , Vm Nigon
Virology, 1987, 160, pp.301-304
Journal articles hal-00314242v1
Image document

Using mouse genetics to investigate thyroid hormone signaling in the developing and adult brain.

Fabrice Chatonnet , Sabine Richard , Frederic Flamant
Koibuchi N.; Yen P. Thyroid Hormone Disruption and Neurodevelopment, Springer Science+Business Media, 2016, Contemporary Clinical Neuroscience, ⟨10.1007/978-1-4939-3737-0_8⟩
Book sections hal-04231078v1