Frédéric Flamant

Publications

Article dans une revue (100)

Thyroid Hormone Receptors Approach Their 40th Birthday Frédéric Flamant Endocrinology, 2025, 166 (7), pp.bqaf094. ⟨10.1210/endocr/bqaf094⟩ Article dans une revue hal-05209052v1
SOSHI-seq: a high-throughput screening assay to test the functionality of putative response elements for nuclear hormone receptors Shijia Wu,Romain Guyot,Yanis Zekri,Wenzheng Jiang,Frédéric Flamant Scientific Reports, 2025, 16 (1), pp.436. ⟨10.1038/s41598-025-29970-8⟩ Article dans une revue hal-05473631v1
An Atlas of Thyroid Hormone Responsive Genes in Adult Mouse Hypothalamus Shijia Wu,Julien Dellinger,Suzy Markossian,Yves Dusabyinema,Romain Guyotet al. Endocrinology, 2025, 166 (6), ⟨10.1210/endocr/bqaf084⟩ Article dans une revue hal-05082499v1
Thyroid Hormones Act as a Timer for the Postnatal Maturation of Parvalbumin Neurons in Mouse Neocortex Juan Ren,Suzy Markossian,Romain Guyot,Denise Aubert,Jacques Brocardet al. Thyroid, 2025, 35 (12), pp.1443-1452. ⟨10.1177/10507256251390868⟩ Article dans une revue hal-05443982v1
Effect of in utero and lactational exposure to a thyroid hormone system disrupting chemical on mouse metabolome and brain transcriptome Rikke Poulsen,Yanis Zekri,Romain Guyot,Frederic Flamant,Martin Hansen Environmental Pollution, 2024, 340, pp.122783. ⟨10.1016/j.envpol.2023.122783⟩ Article dans une revue hal-04501084v1
The human OPA1 delTTAG mutation induces adult onset and progressive auditory neuropathy in mice Corentin Affortit,Carolanne Coyat,Anissa Rym Saidia,Jean-Charles Ceccato,Majida Charifet al. Cellular and Molecular Life Sciences, 2024, 81, pp.80. ⟨10.1007/s00018-024-05115-4⟩ Article dans une revue hal-04501558v1
Thyroid Hormone Receptors Function in GABAergic Neurons During Development and in Adults Frédéric Flamant,Sabine Richard Endocrinology, 2024, 165 (9), pp.bqae101. ⟨10.1210/endocr/bqae101⟩ Article dans une revue hal-04711889v1
Combining transcriptomics and metabolomics to assess neurodevelopmental alteration caused by in utero exposure of mice to three putative thyroid hormone system disruptors Yanis Zekri,Rikke Poulsen,Martin Hansen,Frederic Flamant,Romain Guyot Toxicology, 2024, 508, pp.153905. ⟨10.1016/j.tox.2024.153905⟩ Article dans une revue hal-04711928v1
Is periventricular heterotopia a useful endpoint for developmental thyroid hormone system disruption in mouse toxicity studies? Louise Ramhøj,Romain Guyot,Terje Svingen,Andreas Kortenkamp,Frederic Flamantet al. Regulatory Toxicology and Pharmacology, 2023, 142, pp.105445. ⟨10.1016/j.yrtph.2023.105445⟩ Article dans une revue hal-04222380v1
Thyroid hormone action during GABAergic neuron maturation: The quest for mechanisms Sabine Richard,Juan Ren,Frederic Flamant Frontiers in Endocrinology, 2023, 14, ⟨10.3389/fendo.2023.1256877⟩ Article dans une revue (article de synthèse) hal-04230619v1
Thyroid hormone as a temporal switch in mouse development Juan Ren,Frederic Flamant European Thyroid Journal , 2023, 12 (2), pp.e220225. ⟨10.1530/etj-22-0225⟩ Article dans une revue hal-04222418v1
Neuronal Blockade of Thyroid Hormone Signaling Increases Sensitivity to Diet-Induced Obesity in Adult Male Mice Eva Rial-Pensado,Laurence Canaple,Romain Guyot,Christoffer Clemmensen,Joëlle Wiersemaet al. Endocrinology, 2023, 164 (4), pp.bqad034. ⟨10.1210/endocr/bqad034⟩ Article dans une revue hal-04041371v1
Brown adipocytes local response to thyroid hormone is required for adaptive thermogenesis in adult male mice Yanis Zekri,Romain Guyot,Inés Garteizgogeascoa Suñer,Laurence Canaple,Amandine Gautier-Steinet al. eLife, 2022, 11, pp.e81996. ⟨10.7554/elife.81996⟩ Article dans une revue hal-03958312v1
An Atlas of Thyroid Hormone Receptors’ Target Genes in Mouse Tissues Yanis Zekri,Romain Guyot,Frederic Flamant International Journal of Molecular Sciences, 2022, 23 (19), pp.11444. ⟨10.3390/ijms231911444⟩ Article dans une revue hal-03885312v1
Prenatal exposure to paraquat and nanoscaled TiO2 aerosols alters the gene expression of the developing brain Quentin Hamdaoui,Yanis Zekri,Sabine Richard,Denise Aubert,Romain Guyotet al. Chemosphere, 2022, 287 (Pt 3), pp.132253. ⟨10.1016/j.chemosphere.2021.132253⟩ Article dans une revue hal-03403617v1
A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice Corentin Affortit,Fabian Blanc,Jamal Nasr,Jean-Charles Ceccato,Suzy Markossianet al. Science Signaling, 2022, 15 (738), ⟨10.1126/scisignal.abj4583⟩ Article dans une revue hal-03746401v1
Functional Definition of Thyroid Hormone Response Elements Based on a Synthetic STARR-seq Screen Frédéric Flamant,Yanis Zekri,Romain Guyot Endocrinology, 2022, 163 (8), pp.bqac084. ⟨10.1210/endocr/bqac084⟩ Article dans une revue hal-03746531v1
A CRISPR/Cas9-engineered avatar mouse model of monocarboxylate transporter 8 deficiency displays distinct neurological alterations Víctor Valcárcel-Hernández,Marina Guillén-Yunta,Miranda Bueno-Arribas,Ana Montero-Pedrazuela,Carmen Grijota-Martínezet al. Neurobiology of Disease, 2022, 174, pp.105896. ⟨10.1016/j.nbd.2022.105896⟩ Article dans une revue hal-03887086v1
In vitro assessment of pesticides capacity to act as agonists/antagonists of the thyroid hormone nuclear receptors Yanis Zekri,Laure Dall Agnol,Frederic Flamant,Romain Guyot iScience, 2021, 24 (9), pp.1-21. ⟨10.1016/j.isci.2021.102957⟩ Article dans une revue hal-03520452v1
Thyroid hormone and mammalian tissue regeneration Frederic Flamant Annales d'Endocrinologie = Annals of Endocrinology, 2021, 82 (3-4), pp.158-160. ⟨10.1016/j.ando.2020.02.002⟩ Article dans une revue hal-03285023v1
Metrological Characterization of an Aerosol Exposure Chamber to Explore the Inhalation Effects of the Combination of Paraquat and TiO2 Nano-objects Quentin Hamdaoui,A. Bencsik,Frederic Flamant,Simon Delcour,Tatiana Macéet al. Aerosol and Air Quality Research, 2021, 21 (8), pp.200626. ⟨10.4209/aaqr.200626⟩ Article dans une revue hal-03416520v1
Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic Yanis Zekri,Frederic Flamant,Karine Gauthier Cells, 2021, 10 (6), pp.1327. ⟨10.3390/cells10061327⟩ Article dans une revue hal-03278371v1
Thyroid hormone receptor α in skeletal muscle is essential for T3‐mediated increase in energy expenditure Trine S Nicolaisen,Anders B Klein,Oksana Dmytriyeva,Jens Lund,Lars R Ingerslevet al. FASEB Journal, 2020, 34 (11), pp.15480-15491. ⟨10.1096/fj.202001258RR⟩ Article dans une revue hal-02996920v1
ERGO: Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters Henrik Holbech,Peter Matthiessen,Martin Hansen,Gerrit Schuurmann,Dries Knapenet al. International Journal of Molecular Sciences, 2020, 21 (8), pp.2954. ⟨10.3390/ijms21082954⟩ Article dans une revue hal-02904035v1
A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons Sabine Richard,Romain Guyot,Martin Rey-Millet,Margaux Prieux,Suzy Markossianet al. iScience, 2020, 23 (3), pp.100899. ⟨10.1016/j.isci.2020.100899⟩ Article dans une revue hal-03634530v2
PRMT1 Is Critical for the Transcriptional Activity and the Stability of the Progesterone Receptor. Lucie Malbeteau,Coralie Poulard,Cécile Languilaire,Ivan Mikaelian,Frederic Flamantet al. iScience, 2020, 23 (6), pp.101236. ⟨10.1016/j.isci.2020.101236⟩ Article dans une revue hal-03019840v1
Two Novel Cases of Resistance to Thyroid Hormone Due to THRA Mutation Albane E Le Maire,Natacha Bouhours-Nouet,Jessica Soamalala,Delphine Mirebeau-Prunier,Matteo Paloniet al. Thyroid, 2020, 30 (8), pp.1217-1221. ⟨10.1089/thy.2019.0602⟩ Article dans une revue hal-04707333v1
Metabolomic Profiling of Body Fluids in Mouse Models Demonstrates that Nuclear Magnetic Resonance Is a Putative Diagnostic Tool for the Presence of Thyroid Hormone Receptor α1 Mutations Houda Boumaza,Suzy S. Markossian,Baptiste Busi,Gilles J.P. Rautureau,Karine Gauthieret al. Thyroid, 2019, 29 (9), pp.1327-1335. ⟨10.1089/thy.2018.0730⟩ Article dans une revue hal-02983685v1
Pesticides, perturbateurs endocriniens de la glande thyroïde ? Frederic Flamant Les cahiers de la Recherche : Santé, Environnement, Travail, 2019, Les perturbateurs endocriniens, 13, pp.23-25 Article dans une revue anses-02445614v1
Evidence for hormonal control of heart regenerative capacity during endothermy acquisition Kentaro Hirose,Alexander Payumo,Stephen Cutie,Alison Hoang,Hao Zhanget al. Science, 2019, pp.eaar2038. ⟨10.1126/science.aar2038⟩ Article dans une revue hal-02983719v1
New Case of Thyroid Hormone Resistance α Caused by a Mutation of THRA/TRα1 Hui Sun,Haiying Wu,Rongrong Xie,Fengyun Wang,Ting Chenet al. Journal of the Endocrine Society, 2019, 3 (3), pp.665-669. ⟨10.1210/js.2019-00011⟩ Article dans une revue hal-02983728v1
CRISPR/Cas9 Editing of the Mouse Thra Gene Produces Models with Variable Resistance to Thyroid Hormone Suzy S. Markossian,Romain Guyot,Sabine Richard,Marie Teixeira,Nadine Aguileraet al. Thyroid, 2018, 28 (1), pp.139-150. ⟨10.1089/thy.2017.0389⟩ Article dans une revue hal-03278383v1
Two Protocols to Study the Interactions of Thyroid Hormone Receptors with Other Proteins and Chromatin Henrik Holbech,Peter Matthiessen,Martin Hansen,Gerrit Schüürmann,Dries Knapenet al. Frontiers in Endocrinology, 2018, 1801 (3), pp.9-16. ⟨10.1007/978-1-4939-7902-8_2⟩ Article dans une revue hal-03278376v1
Regulation of T3 Availability in the Developing Brain: The Mouse Genetics Contribution Sabine Richard,Frederic Flamant Frontiers in Endocrinology, 2018, 9, 11 p. ⟨10.3389/fendo.2018.00265⟩ Article dans une revue (article de synthèse) hal-02621572v1
Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing Marie Teixeira,Bénédicte F. Py,Christophe Bosc,Daphné Laubreton,Marie-Jo Moutinet al. Scientific Reports, 2018, 8 (1), pp.4679. ⟨10.1038/s41598-018-22724-9⟩ Article dans une revue hal-01908850v1
Neuronal expression of a thyroid hormone receptor α mutation alters mouse behaviour S. Richard,N. Aguilera,M. Thévenet,O. Dkhissi-Benyahya,Frederic Flamant Behavioural Brain Research, 2017, 321, pp.18-27. ⟨10.1016/j.bbr.2016.12.025⟩ Article dans une revue hal-03278396v1
Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin Wenyue Guan,Romain Guyot,Jacques Samarut,Frederic Flamant,Jiemin Wonget al. Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (31), pp.8229-8234. ⟨10.1073/pnas.1702192114⟩ Article dans une revue hal-03278385v1
Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature Frederic Flamant,Sheue-Yann Cheng,Anthony Hollenberg,Lars Moeller,Jacques Samarutet al. Endocrinology, 2017, 158 (7), pp.2052-2057. ⟨10.1210/en.2017-00250⟩ Article dans une revue hal-03278395v1
Genetic Investigation of Thyroid Hormone Receptor Function in the Developing and Adult Brain Frederic Flamant,Karine Gauthier,Sabine Richard Current Topics in Developmental Biology, 2017, 125, pp.303-335. ⟨10.1016/bs.ctdb.2017.01.001⟩ Article dans une revue hal-03278392v1
CRISPR/Cas9: a breakthrough in generating mouse models for endocrinologists Suzy S. Markossian,Frederic Flamant Journal of Molecular Endocrinology, 2016, 57 (2), pp.R81-R92. ⟨10.1530/JME-15-0305⟩ Article dans une revue hal-03278399v1
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease Brian Finan,Christoffer Clemmensen,Zhimeng Zhu,Kerstin Stemmer,Karine Gauthieret al. Cell, 2016, 167 (3), pp.843-857.e14. ⟨10.1016/j.cell.2016.09.014⟩ Article dans une revue hal-03278397v1
Futures Challenges in Thyroid Hormone Signaling Research Frederic Flamant Frontiers in Endocrinology, 2016, 7, ⟨10.3389/fendo.2016.00058⟩ Article dans une revue hal-02635655v1
Thyroid Hormone signaling in the mouse retina Patrick Arbogast,Frederic Flamant,Pierre Godement,Martin Glösmann,Leo Peichl PLoS ONE, 2016, 11 (12), 20 p. ⟨10.1371/journal.pone.0168003⟩ Article dans une revue hal-01602508v1
A temporary compendium of thyroid hormone target genes in brain Fabrice Chatonnet,Frederic Flamant,Beatriz Morte Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2015, 1849 (2), pp.122-129. ⟨10.1016/j.bbagrm.2014.05.023⟩ Article dans une revue istex hal-02164764v1
TRα receptor mutations extend the spectrum of syndromes of reduced sensitivity to thyroid hormone Virginie Vlaeminck-Guillem,Stéphanie Espiard,Frederic Flamant,Jean-Louis Wémeau La Presse Médicale, 2015, 44 (11), pp.1103-1112. ⟨10.1016/j.lpm.2015.07.022⟩ Article dans une revue istex hal-03278401v1
Editorial: “Thyroid Hormone in Brain and Brain Cells” Frederic Flamant,Noriyuki Koibuchi,Juan Bernal Frontiers in Endocrinology, 2015, 6, pp.99. ⟨10.3389/fendo.2015.00099⟩ Article dans une revue hal-03278404v1
A Novel Mutation in THRA Gene Associated With an Atypical Phenotype of Resistance to Thyroid Hormone Stéphanie Espiard,Frédérique Savagner,Frederic Flamant,Virginie Vlaeminck-Guillem,Romain Guyotet al. Journal of Clinical Endocrinology and Metabolism, 2015, 100 (8), pp.2841-2848. ⟨10.1210/jc.2015-1120⟩ Article dans une revue hal-02952401v1
Toxicogenomic analysis of the ability of brominated flame retardants TBBPA and BDE-209 to disrupt thyroid hormone signaling in neural cells Romain Guyot,Fabrice Chatonnet,Benjamin Gillet,Sandrine Hughes,Frederic Flamant Toxicology, 2014, 325, pp.125-132. ⟨10.1016/j.tox.2014.08.007⟩ Article dans une revue istex hal-03278405v1
The Targeted Inactivation of TRβ Gene in Thyroid Follicular Cells Suggests a New Mechanism of Regulation of Thyroid Hormone Production Samia Selmi-Ruby,Lamia Bouazza,Maria-Jesus Obregon,Aude Conscience,Frederic Flamantet al. Endocrinology, 2014, 155 (2), pp.635-646. ⟨10.1210/en.2013-1435⟩ Article dans une revue hal-03278422v1
Purkinje cells and Bergmann glia are primary targets of the TRα1 thyroid hormone receptor during mouse cerebellum postnatal development. Teddy Fauquier,Fabrice Chatonnet,Frédéric Picou,Sabine Richard,Nicolas Fossatet al. Development (Cambridge, England), 2014, 141 (1), pp.166-75. ⟨10.1242/dev.103226⟩ Article dans une revue hal-00968730v1
Autonomous functions of murine thyroid hormone receptor TRα and TRβ in cochlear hair cells Juliane Dettling,Christoph Franz,Ulrike Zimmermann,Sze Chim Lee,Andreas Bresset al. Molecular and Cellular Endocrinology, 2014, 382 (1), pp.26-37. ⟨10.1016/j.mce.2013.08.025⟩ Article dans une revue hal-03278424v1
Minireview: Deciphering Direct and Indirect Influence of Thyroid Hormone With Mouse Genetics N. Aguilera,M. Thévenet,O. Dkhissi-Benyahya,Frédéric Picou,Teddy Fauquieret al. Molecular Endocrinology, 2014, 28 (4), pp.429-441. ⟨10.1210/me.2013-1414⟩ Article dans une revue hal-03278418v1
Direct and indirect consequences on gene expression of a thyroid hormone receptor alpha 1 mutation restricted to Sertoli cells Fabrice Chatonnet,Gabriel Livera,Betty Fumel,Sophie Fouchécourt,Frederic Flamant Molecular Reproduction and Development, 2014, 81 (12), pp.1159 - 1166. ⟨10.1002/mrd.22437⟩ Article dans une revue istex hal-01130502v1
Chondrocytes Play a Major Role in the Stimulation of Bone Growth by Thyroid Hormone Clémence Desjardin,Cyril Charles,Catherine Benoist-Lasselin,Julie Riviere,Maïlys Gilleset al. Endocrinology, 2014, 155 (8), pp.3123-3135. ⟨10.1210/en.2014-1109⟩ Article dans une revue hal-01193997v1
Nongenomic, TRβ-Dependent, Thyroid Hormone Response Gets Genetic Support Karine Gauthier,Frederic Flamant Endocrinology, 2014, 155 (9), pp.3206-3209. ⟨10.1210/en.2014-1597⟩ Article dans une revue hal-03278412v1
Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells Hasan Avci,Clement Lebrun,Rosine Wehrle,Mohamed Doulazmi,Marie-Pierre Morelet al. Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (8), pp.E766-E775. ⟨10.1073/pnas.1210626110⟩ Article dans une revue hal-03278425v1
[Thyroid hormone T3 triggers the developmental loss of axonal regenerative capacity] Hasan X. Avci,Frederic Flamant,Isabelle Dusart Médecine/Sciences, 2013, 29 (3), pp.245--247. ⟨10.1051/medsci/2013293005⟩ Article dans une revue hal-01543628v1
Thyroid hormone limits postnatal Sertoli cell proliferation in vivo by activation of its alpha1 isoform receptor (TRalpha1) present in these cells and by regulation of Cdk4/JunD/c-myc mRNA levels in mice Betty Fumel,Marie-Justine Guerquin,Gabriel Livera,Christophe Staub,Michèle Magistriniet al. Biology of Reproduction, 2012, 87 (1), pp.1-9. ⟨10.1095/biolreprod.111.098418⟩ Article dans une revue hal-01129659v1
Profound morphological and functional changes of rodent Purkinje cells between the first and the second postnatal weeks: a metamorphosis? Isabelle Dusart,Frederic Flamant Frontiers in Neuroanatomy, 2012, 6, pp.11. ⟨10.3389/fnana.2012.00011⟩ Article dans une revue hal-01543632v1
Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor alpha 1 and kruppel-like factor 9 in Purkinje cells Hasan X. Avci,Clement Lebrun,Rosine Wehrle,Mohamed Doulazmi,Fabrice Chatonnetet al. Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (35), pp.14206-14211. ⟨10.1073/pnas.1119853109⟩ Article dans une revue hal-01545809v1
Genome-Wide Search Reveals the Existence of a Limited Number of Thyroid Hormone Receptor Alpha Target Genes in Cerebellar Neurons Fabrice Chatonnet,Romain Guyot,Frédéric Picou,Maria Bondesson,Frederic Flamant PLoS ONE, 2012, 7 (5), pp.e30703. ⟨10.1371/journal.pone.0030703⟩ Article dans une revue hal-02164760v1
Hormone thyroïdienne et développement du cervelet : effets directs ou indirects ? Fabrice Chatonnet,Teddy Fauquier,Frederic Picou,Romain Guyot,Frederic Flamant Annales d'Endocrinologie = Annals of Endocrinology, 2011, 72 (2), pp.99-102. ⟨10.1016/j.ando.2011.03.012⟩ Article dans une revue hal-02164736v1
Otx2 Gene Deletion in Adult Mouse Retina Induces Rapid RPE Dystrophy and Slow Photoreceptor Degeneration. Francis Béby,Michael Housset,Nicolas Fossat,Coralie Le Greneur,Frederic Flamantet al. PLoS ONE, 2010, 5 (7), pp.e11673. ⟨10.1371/journal.pone.0011673⟩ Article dans une revue hal-00506174v1
Modeling the role of mid-wavelength cones in circadian responses to light. Ouria Dkhissi-Benyahya,Claude Gronfier,Wena de Vanssay,Frederic Flamant,Howard M. Cooper Neuron, 2007, 53 (5), pp.677-87. ⟨10.1016/j.neuron.2007.02.005⟩ Article dans une revue inserm-00135926v1
A combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum. Laure Quignodon,Carmen Grijota-Martinez,Emmanuel Compe,Romain Guyot,Nathalie Allioliet al. Journal of Molecular Endocrinology, 2007, 39 (1), pp.17-28. ⟨10.1677/JME-06-0054⟩ Article dans une revue hal-00206218v1
Peripheral circulation of the prion infectious agent in transgenic mice expressing the ovine prion protein gene in neurons only C. Crozet,S. Lezmi,Frederic Flamant,J. Samarut,T. Baronet al. Journal of Infectious Diseases, 2007, 195 (7), pp.997-1006. ⟨10.1086/512085⟩ Article dans une revue hal-00180826v1
Thyroid hormone signaling is highly heterogeneous during pre- and postnatal brain development Laure Quignodon,C. Legrand,Nathalie Allioli,A. Guadano-Ferraz,Joaquin Bernalet al. Journal of Molecular Endocrinology, 2004, 33, pp.467-476. ⟨10.1677/jme.1.01570⟩ Article dans une revue hal-02672363v1
Both thyroid hormone receptor (TR)beta1 and TRbeta2 isoforms contribute to the regulation of hypothalamic Thyrotropin-releasing hormone S.M. Dupré,H. Guissouma,Frederic Flamant,I. Seugnet,T.S. Scanlanet al. Endocrinology, 2004, 145 (5), pp.2337-2345. ⟨10.1210/en.2003-1209⟩ Article dans une revue hal-02675694v1
Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life W. Mai,M.F. Janier,Nathalie Allioli,Laure Quignodon,T. Chuzelet al. Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (28), pp.10332-10337. ⟨10.1073/pnas.0401843101⟩ Article dans une revue hal-02677765v1
The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification E. Bonnafe,M. Touka,A. Aitlounis,D. Baas,E. Barraset al. Molecular and Cellular Biology, 2004, 24 (10), pp.4417-4427. ⟨10.1128/MCB.24.10.4417-4427.2004⟩ Article dans une revue hal-02679672v1
Thyroid hormone receptors : lessons from knockout and knock-in mutant mice Frederic Flamant,Jacques Samarut Trends in Endocrinology and Metabolism = Trends in Endocrinology & Metabolism , 2003, 14 (2), pp.85-90 Article dans une revue hal-02670632v1
Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice P.M. Yen,Xu Ping Feng,Frederic Flamant,Y. Chen,R.L. Walkeret al. EMBO Reports, 2003, 4 (6), pp.581-587 Article dans une revue hal-02676180v1
Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum A.L. Poguet,C. Legrand,Xu Ping Feng,P.M. Yen,P. Meltzeret al. Developmental Biology, 2003, 254, pp.188-199 Article dans une revue hal-02671535v1
Null mutant mice for thyroid hormone receptors. In Thyroid hormone receptors. Karine Gauthier,Denise Aubert,Olivier Chassande,Frederic Flamant,Jacques Samarut Methods in molecular medicine, 2002, 22, pp.13-29 Article dans une revue hal-00023831v1
Congenital hypothyroid Pax8-/- mutant mice can be rescued by inactivating the TRalpha gene Frederic Flamant,A.L. Poguet,Michelina Plateroti,O. Chanssade,K. Gauthieret al. Molecular Endocrinology -Baltimore-, 2002, 16 (1), pp.24-32 Article dans une revue hal-02679582v1
Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors D. Baas,C. Legrand,Jacques Samarut,Frederic Flamant Proceedings of the National Academy of Sciences of the United States of America, 2002, 99 (5), pp.2907-2911. ⟨10.1073/pnas.052482299⟩ Article dans une revue hal-02678333v1
Florid Plaque in ovine PrP transgenic mice infected with an experimental ovine BSE. C. Crozet,A. Bencsik,Frederic Flamant,S. Lezmi,Jacques Samarutet al. EMBO Reports, 2001, 21 (10), pp.952-956. ⟨10.1093/embo-reports/kve204⟩ Article dans une revue hal-00023828v1
Efficient Transmission of Two Different Sheep Scrapie Isolates in Transgenic Mice Expressing the Ovine PrP Gene Carole Crozet,Frederic Flamant,Anna Bencsik,Denise Aubert,Jacques Samarutet al. Journal of Virology, 2001, 75 (11), pp.5328-5334. ⟨10.1128/JVI.75.11.5328-5334.2001⟩ Article dans une revue hal-03634581v1
Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine PrP gene Carole Crozet,Frederic Flamant,A. Bencsik,Denise Aubert,Jacques Samarutet al. Journal of Virology, 2001, 75 (11), pp.5328-5334 Article dans une revue hal-02672143v1
A novel growth -factor-dependent myeloid cell line derived from mouse bone marrow cells contains progenitors endowed with high proliferative potential V. Revol,I. Tsuboi,Frederic Flamant,Jacques Samarut,J.P. Blanchetet al. Experimental Hematology, 1999, 27 (1), pp.88-98 Article dans une revue hal-02683916v1
Thyroid hormone receptor knockouts : their contribution to our understanding of thyroid hormone resistance Olivier Chassande,Frederic Flamant,Jacques Samarut Current Opinion in Endocrinology and Diabetes, 1999, 6, pp.293-300 Article dans une revue hal-02693744v1
Eukaryotic conditional expression system T. Sourisseau,Y. Le Dréan,G. Salbert,Frederic Flamant,D. Michel Biotechniques, 1999, 27, pp.106-110 Article dans une revue hal-02688895v1
Involvement of thyroid hormone and its alpha receptor in avian neurulation Frederic Flamant,Jacques Samarut Developmental Biology, 1998, 197, pp.1-11 Article dans une revue hal-02683768v1
Identification of transcripts initiated from an internal promoter in the c-erbA-alpha locus that encode inhibitors of retinoic acid receptor-alpha and triiodothyronine receptor activities Olivier Chassande,A. Fraichard,K. Gauthier,Frederic Flamant,C. Legrandet al. Molecular Endocrinology -Baltimore-, 1997, 11 (9), pp.1278-1290 Article dans une revue hal-02695326v1
The osteoclast generation : an in vitro and in vivo study with a genetically labelled avian monocytic cell line F. Solari,Frederic Flamant,Yan Cherel,Monique Wyers,Pierre Jurdic Journal of Cell Science, 1996, 109, pp.1203-1213 Article dans une revue hal-02691819v1
Virofection : a one-step procedure for using replication-defective retrovirus vectors Frederic Flamant,Jacques Samarut Virology, 1995, 211, pp.234-240 Article dans une revue hal-02705128v1
Vectors derived from avian leucosis and sarcoma viruses Frederic Flamant,Cosset François-Loïc,Jacques Samarut Journal of Molecular Medicine, 1995, 73, pp.181-187 Article dans une revue hal-02704566v1
Replication-competent and -defective retrovirus vectors for oncogenic studies Jacques Samarut,Frederic Flamant,J.M. Heard Methods in Enzymology, 1995, 254, pp.206-228 Article dans une revue hal-02706921v1
Virofection: a new procedure to achieve stable expression of genes transferred into early embryos Frederic Flamant,Barbara Demeneix,C. Benoist,Suzy Markossian-Belin,Jacques Samarut International Journal of Developmental Biology, 1994, 38, pp.751-757 Article dans une revue hal-02699936v1
Use of helper cells with two host ranges to generate high-titer retroviral vectors Cosset François-Loïc,A. Girod,Frederic Flamant,A. Drynda,C. Ronfortet al. Virology, 1993, 193, pp.385-395 Article dans une revue hal-02703909v1
Importance of 3' non-coding sequences for efficient retrovirus-mediated gene transfer in avian cells revealed by self-inactivating vectors Frederic Flamant,Denise Aubert,C. Legrand,Cosset François-Loïc,Jacques Samarut Journal of General Virology, 1993, 74, pp.39-46 Article dans une revue hal-02699527v1
Importance of 3' non-coding sequences for efficient retrovirus-mediated gene transfer in avian cells revealed by self-inactivating vectors Frederic Flamant,Denise Aubert,C. Legrand,F.-L. Cosset,J. Samarut Journal of General Virology, 1993, 74 (1), pp.39-46. ⟨10.1099/0022-1317-74-1-39⟩ Article dans une revue hal-03634586v1
Identifying genes involved in the variability of genetic fatness in the growing chicken M. Douaire,N. Le Fur,C. El Khadir-Mounier,Paul Langlois,Frederic Flamantet al. Poultry Science, 1992, 71, pp.1911-1920 Article dans une revue hal-02699766v1
Packaging cells for avian leukosis virus-based vectors with various host ranges Cosset François-Loïc,C. Ronfort,R.M. Molina,Frederic Flamant,A. Dryndaet al. Journal of Virology, 1992, 66 (9), pp.5671-5676 Article dans une revue hal-02703488v1
Self-inactivating avian leukosis derived retroviral vectors for gene transfer and stable expression into cultured avian cells Denise Aubert,Camille Bagnis,Frederic Flamant,M. Garcia,Jacques Samarut Virology, 1991, 10, pp.71-76 Article dans une revue hal-02708464v1
ApoVLDLII gene transcription in immature cockerels without estradiol stimulation. M. Douaire,Paul Langlois,Frederic Flamant,J. Mallard Comparative Biochemistry and Physiology, 1990, 97B (1), pp.55-57 Article dans une revue hal-02699564v1
In vitro synthesis of infectious retroviral RNA Frederic Flamant,J Sorge Journal of Virology, 1988, 62 (5), pp.1827-1831. ⟨10.1128/JVI.62.5.1827-1831.1988⟩ Article dans une revue hal-03278437v1
CONSTRUCTION ET UTILISATION DE VECTEURS DÉRIVÉS DU VIRUS DE L'ÉRYTHROBLASTOSE AVIAIRE POUR LE TRANSFERT DE GÈNES CHEZ LE POULET Frederic Flamant,Benchaibi M,Thoraval P,Chambonnet F,Savatier Pet al. Annales de Recherches Vétérinaires, 1988, 19 (1), pp.85-86 Article dans une revue hal-00901808v1
An embryonic DNA-binding protein specific for the promoter of the retrovirus long terminal repeat Frederic Flamant,C Gurin,J Sorge Molecular and Cellular Biology, 1987, 7 (10), pp.3548-3553. ⟨10.1128/mcb.7.10.3548-3553.1987⟩ Article dans une revue hal-03278438v1
Tissue specificity of retrovirus expression in inoculated avian embryos revealed by in situ hybridization to whole-body section. Frederic Flamant,D. Leguellec,Ghislain Verdier,Vm Nigon Virology, 1987, 160, pp.301-304 Article dans une revue hal-00314242v1

Communication dans un congrès (3)

The effects of prenatal co-exposure to environmental toxins on the developing brain: the example of the paraquat herbicide and nanoscaled TiO2 aerosols. Anna Bencsik,Quentin Hamdaoui,Frederic Flamant,Francois Gaie-Levrel 7th Symposium of radiobiology - International Military Radiation & Innovation Symposium (IMRIS), Oct 2024, Paris, France. pp.Communication orale Communication dans un congrès anses-04814096v1
An inhalation study combining nanoTiO2 and Paraquat exposure in a transgenic mouse model of Parkinson's disease: a novel approach to study nanopesticides impact on brain function Bencsik Anna,Quentin Hamdaoui,J. Noireaux,P. Fisicaro,N. Gadotet al. 15ème Colloque de la Société Neurosciences, NeuroFrance, Visioconférence, May 2021, Strasbourg, France Communication dans un congrès anses-04602158v1
Development and metrological characterization of an aerosol generation device dedicated to inhalation toxicology studies: the nanopesticide case Quentin Hamdaoui,François Gaie-Levrel,Tatiana Macé,Sophie Vaslin-Reimann,Frédéric Flamantet al. 19th International Congress of Metrology, Sep 2019, Paris, France. pp.07002, ⟨10.1051/metrology/201907002⟩ Communication dans un congrès anses-03725755v1

Chapitre d'ouvrage (2)

Using mouse genetics to investigate thyroid hormone signaling in the developing and adult brain. Fabrice Chatonnet,Sabine Richard,Frederic Flamant Koibuchi N.; Yen P. Thyroid Hormone Disruption and Neurodevelopment, Springer Science+Business Media, 2016, Contemporary Clinical Neuroscience, ⟨10.1007/978-1-4939-3737-0_8⟩ Chapitre d'ouvrage hal-04231078v1
Null Mutant Mice for Thyroid Hormone Receptors Karine Gauthier,Olivier Chassande,Frederic Flamant,Jacques Samarut,Denise Aubert Thyroid Hormone Receptors, Humana Press; Humana Press, pp.13-29, 2002, ⟨10.1385/1-59259-174-4:13⟩ Chapitre d'ouvrage hal-03634578v1

Pré-publication, Document de travail (2)

Thyroid hormones maintain parvalbumin neuron functions in mouse neocortex Juan Ren,Suzy Markossian,Romain Guyot,Denise Aubert,Dongdong Liet al. 2024 Pré-publication, Document de travail hal-04727836v1
A point mutation in the AF-2 domain of thyroid hormone receptor alpha1 expressed after CRE mediated recombination partially recapitulates hypothyroidism. Laure Quignodon,Séverine Vincent,Harald Winter,Jacques Samarut,Frederic Flamant 2007 Pré-publication, Document de travail ensl-00159617v1