Jean-Noël Freund INSERM U1256-NGEREUniversité de Lorraine

Publications

Article dans une revue (146)

Renin-Angiotensin System Drives Leukemia Progression by Reprogramming the Niche Blandine Guffroy,Laurent Miguet,Bruno Lioure,Jean-Noel Freund,Manuela Tavian Discovery medicine, 2025, 37 (193), pp.409-410. ⟨10.24976/Discov.Med.202537193.34⟩ Article dans une revue inserm-04976579v1
CD32 captures committed haemogenic endothelial cells during human embryonic development Rebecca Scarfò,Lauren N. Randolph,Monah Abou Alezz,Mahassen El Khoury,Amélie Gerschet al. Nature Cell Biology, 2024, ⟨10.1038/s41556-024-01403-0⟩ Article dans une revue hal-04544615v1
Macrophage depletion overcomes human hematopoietic cell engraftment failure in zebrafish embryo Reine El Omar,Naoill Abdellaoui,Safiatou T Coulibaly,Laura Fontenille,François Lanzaet al. Cell Death and Disease, 2024, 15 (5), pp.305. ⟨10.1038/s41419-024-06682-x⟩ Article dans une revue hal-04567212v1
MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice. Sanjeev Kiran Gotru,Elmina Mammadova-Bach,Georgios Sogkas,Michael K Schuhmann,Karen Schmittet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2023, ⟨10.1161/ATVBAHA.122.318115⟩ Article dans une revue hal-04149721v1
General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions. Susanna Säisä-Borreill,Guillaume Davidson,Thomas Kleiber,Andréa Thevenot,Elisabeth Martinet al. Cell death and differentiation, 2023, ⟨10.1038/s41418-022-01109-6⟩ Article dans une revue hal-03942206v1
The Appendix Orchestrates T-Cell Mediated Immunosurveillance in Colitis-Associated Cancer Maxime Collard,Julien Tourneur-Marsille,Mathieu Uzzan,Miguel Albuquerque,Maryline Royet al. Cellular and Molecular Gastroenterology and Hepatology, 2023, 15 (3), pp.665-687. ⟨10.1016/j.jcmgh.2022.10.016⟩ Article dans une revue hal-03926262v1
Mesalazine initiates an anti-oncogenic β-catenin / MUCDHL negative feed-back loop in colon cancer cells by cell-specific mechanisms Emilie Bersuder,Chloe Terciolo,Mathilde Lechevrel,Elisabeth Martin,Celine Quesnelleet al. Biomedicine and Pharmacotherapy, 2022, 146, pp.112543. ⟨10.1016/j.biopha.2021.112543⟩ Article dans une revue hal-03788694v1
CDX2 controls genes involved in the metabolism of 5-fluorouracil and is associated with reduced efficacy of chemotherapy in colorectal cancer Jean-Baptiste Delhorme,Emilie Bersuder,Chloé Terciolo,Ourania Vlami,Marie Pierrette Chenardet al. Biomedicine and Pharmacotherapy, 2022, 147, pp.112630. ⟨10.1016/j.biopha.2022.112630⟩ Article dans une revue hal-03788706v1
Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRα1, in intestinal lesions Maria Virginia Giolito,Théo La Rosa,Diana Farhat,Serguei Bodoirat,Gabriela D. A. Guardiaet al. Molecular Oncology, 2022, ⟨10.1002/1878-0261.13298⟩ Article dans une revue hal-03792241v1
Concurrent CDX2 cis -deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL Marie Passet,Rathana Kim,Stéphanie Gachet,François Sigaux,Julie Chaumeilet al. Blood, 2022, 139 (24), pp.3505-3518. ⟨10.1182/blood.2021014723⟩ Article dans une revue hal-03788702v1
CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition Ava Galland,Victor Gourain,Karima Habbas,Yonca Güler,Elisabeth Martinet al. Molecular Oncology, 2021, 15 (9), pp.2318-2329. ⟨10.1002/1878-0261.12982⟩ Article dans une revue hal-03713623v1
A Core Response to the CDX2 Homeoprotein During Development and in Pathologies Victor Gourain,Isabelle Duluc,Claire Domon-Dell,Jean-Noël Freund Frontiers in Genetics, 2021, 12, pp.744165. ⟨10.3389/fgene.2021.744165⟩ Article dans une revue hal-03788711v1
Murine intestinal stem cells are highly sensitive to modulation of the T3/TRα1-dependent pathway Matthias Godart,Carla Frau,Diana Farhat,Maria Virginia Giolito,Catherine Jamardet al. Development (Cambridge, England), 2021, 148 (8), ⟨10.1242/dev.194357⟩ Article dans une revue hal-03791609v1
Temporal multiomic modeling reveals a B-cell receptor proliferative program in chronic lymphocytic leukemia Cedric Schleiss,Raphael Carapito,Luc-Matthieu Fornecker,Leslie Muller,Nicodème Paulet al. Leukemia, 2021, 35, pp.1463-1474. ⟨10.1038/s41375-021-01221-5⟩ Article dans une revue hal-03206125v1
Deciphering the Role of Intestinal Crypt Cell Populations in Resistance to Chemotherapy Carla Frau,Catherine Jamard,Gaspard Delpouve,Gabriela D.A. Guardia,Christelle Machonet al. Cancer Research, 2021, 81 (10), pp.2730-2744. ⟨10.1158/0008-5472.CAN-20-2450⟩ Article dans une revue hal-03810274v1
CDX2 regulates ACE expression in blood development and leukemia cells Reine El Omar,Emmanuelle Julien,Katia Biasch,Blandine Guffroy,Bruno Lioureet al. Blood Advances, 2021, 5 (7), pp.2012-2016. ⟨10.1182/bloodadvances.2020003563⟩ Article dans une revue hal-03431252v1
CDX2 inducible microRNAs sustain colon cancer by targeting multiple DNA damage response pathway factors Swati Priya,Ekjot Kaur,Swati Kulshrestha,Awadhesh Pandit,Isabelle Grosset al. Journal of Cell Science, 2021, 134 (15), ⟨10.1242/jcs.258601⟩ Article dans une revue hal-03788695v1
The atypical cadherin MUCDHL antagonizes colon cancer formation and inhibits oncogenic signaling through multiple mechanisms Marine Beck,Mathilde Baranger,Ahlam Moufok-Sadoun,Emilie Bersuder,Isabelle Hinkelet al. Oncogene, 2021, 40, pp.522-535. ⟨10.1038/s41388-020-01546-y⟩ Article dans une revue hal-03044463v1
Renin-angiotensin system is involved in embryonic emergence of hematopoietic stem/progenitor cells Emmanuelle Julien,Katia Biasch,Reine El Omar,Jean-Noël Freund,Christian Gachetet al. STEM CELLS, 2021, 39 (5), pp.636-649. ⟨10.1002/stem.3339⟩ Article dans une revue hal-03558010v1
Anticancer activity of ruthenium and osmium cyclometalated compounds: identification of ABCB1 and EGFR as resistance mechanisms Cynthia Licona,Jean-Baptiste Delhorme,Gilles Riegel,Vania Vidimar,Ricardo Cerón-Camachoet al. Inorganic Chemistry Frontiers, 2020, 7 (3), pp.678-688. ⟨10.1039/C9QI01148J⟩ Article dans une revue hal-03013615v1
Actomyosin, vimentin and LINC complex pull on osteosarcoma nuclei to deform on micropillar topography Nayana Tusamda Wakhloo,Sebastian Anders,Florent Badique,Melanie Eichhorn,Isabelle Brigaudet al. Biomaterials, 2020, 234, pp.119746. ⟨10.1016/j.biomaterials.2019.119746⟩ Article dans une revue hal-02525268v1
A redox ruthenium compound directly targets PHD2 and inhibits the HIF1 pathway to reduce tumor angiogenesis independently of p53 Vania Vidimar,Cynthia Licona,Ricardo Cerón-Camacho,Eric Guérin,Pierre Coliatet al. Cancer Letters, 2019, 440-441, pp.145-155. ⟨10.1016/j.canlet.2018.09.029⟩ Article dans une revue inserm-02363227v1
Severe head dysgenesis resulting from imbalance between anterior and posterior ontogenetic programs Emmanuelle Grall,Victor Gourain,Asmaa Naïr,Elisabeth Martin,Marie-Christine Birlinget al. Cell Death and Disease, 2019, 10 (11), pp.812. ⟨10.1038/s41419-019-2040-0⟩ Article dans une revue hal-03682397v1
A Core Proliferative Program Induced By B-Cell Receptor Stimulation in Chronic Lymphocytic Leukemia Cells Cédric Schleiss,Raphaël Carapito,Luc Fornecker,Leslie Muller,Nicodème Paulet al. Blood, 2019, 134, ⟨10.1182/blood-2019-126779⟩ Article dans une revue hal-03408179v1
The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms Camille Balbinot,Olivier Armant,Nabila Elarouci,Laetitia Marisa,Elisabeth Martinet al. Journal of Experimental Medicine, 2018, Epub ahead of print. ⟨10.1084/jem.20170934⟩ Article dans une revue inserm-01707534v1
Chromatin de-condensation by switching substrate elasticity Morgane Rabineau,Florence Flick,Claire Ehlinger,Eric Mathieu,Isabelle Dulucet al. Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-31023-2⟩ Article dans une revue hal-03471678v1
The tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton. Nadine Platet,Isabelle Hinkel,Ludovic Richert,Devadarssen Murdamoothoo,Ahlam Moufok-Sadounet al. Cancer Letters, 2017, 386, pp.57 - 64. ⟨10.1016/j.canlet.2016.10.040⟩ Article dans une revue inserm-01708896v1
Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing C. Balbinot,M. Vanier,O. Armant,A. Nair,J. Penichonet al. Cell Death and Differentiation, 2017, 24 (12), pp.2173-2186. ⟨10.1038/cdd.2017.140⟩ Article dans une revue hal-02552690v1
Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration. Benoît Romain,Radhia Benbrika-Nehmar,Laetitia Marisa,Michèle Legrain,Viviane Lobsteinet al. Oncotarget, 2017, 8 (24), pp.38351-38366. ⟨10.18632/oncotarget.16323⟩ Article dans une revue inserm-01708889v2
Estimation of subject coregistration errors during multimodal preclinical imaging using separate instruments: origins and avoidance of artifacts. Jean-Philippe Dillenseger,Christian Goetz,Amira Sayeh,C Healy,Isabelle Dulucet al. Journal of Medical Imaging, 2017, 4 (03), pp.035503. ⟨10.1117/1.JMI.4.3.035503⟩ Article dans une revue inserm-01708886v1
Distinct mechanisms for opposite functions of homeoproteins Cdx2 and HoxB7 in double-strand break DNA repair in colon cancer cells Christine Soret,Elisabeth Martin,Isabelle Duluc,Françoise Dantzer,Marie Vanieret al. Cancer Letters, 2016, 374 (2), pp.208-215. ⟨10.1016/j.canlet.2016.02.026⟩ Article dans une revue inserm-01708904v1
Enhanced Ghrelin Levels and Hypothalamic Orexigenic AgRP and NPY Neuropeptide Expression in Models of Jejuno-Colonic Short Bowel Syndrome Laura Gillard,Lore Billiauws,Bogdan Stan-Iuga,Lara Ribeiro,Anne-Charlotte Jarryet al. Scientific Reports, 2016, Scientific Reports 6, Article number: 28345 (2016), [Epub ahead of print]. ⟨10.1038/srep28345⟩ Article dans une revue inserm-01346345v1
Broader expression of the mouse platelet factor 4-cre transgene beyond the megakaryocyte lineage Fabien Pertuy,Alicia Aguilar,Catherine Strassel-Risser,Anita Eckly,Jean-Noël Freundet al. Journal of Thrombosis and Haemostasis, 2015, 13 (1), pp.115-125. ⟨10.1111/jth.12784⟩ Article dans une revue hal-03788703v1
Extending the functions of the homeotic transcription factor Cdx2 in the digestive system through nontranscriptional activities Jean-Noël Freund,Isabelle Duluc,Jean-Marie Reimund,Isabelle Gross,Claire Domon-Dell World Journal of Gastroenterology, 2015, 21 (5), pp.1436-1443. ⟨10.3748/wjg.v21.i5.1436⟩ Article dans une revue hal-03788696v1
Cell guidance into quiescent state through chromatin remodeling induced by elastic modulus of substrate Morgane Rabineau,Florence Flick,Eric Mathieu,Annie Tu,Bernard Sengeret al. Biomaterials, 2015, 37, pp.144-155. ⟨10.1016/j.biomaterials.2014.10.023⟩ Article dans une revue istex hal-03811667v1
Transcriptional Regulation of the Intestinal Nuclear Bile Acid Farnesoid X Receptor (FXR) by the caudal-related Homeobox 2 (CDX2) Salvatore Modica,Marica Cariello,Annalisa Morgano,Isabelle Gross,Maria Carmela Veglianteet al. Journal of Biological Chemistry, 2014, 289 (41), pp.28421-28432. ⟨10.1074/jbc.M114.571513⟩ Article dans une revue hal-03807747v1
Combined NADPH Oxidase 1 and Interleukin 10 Deficiency Induces Chronic Endoplasmic Reticulum Stress and Causes Ulcerative Colitis-Like Disease in Mice Xavier Tréton,Eric Pedruzzi,Cécile Guichard,Yannick Ladeiro,Shirin Sedghiet al. PLoS ONE, 2014, 9 (7), pp.e101669. ⟨10.1371/journal.pone.0101669⟩ Article dans une revue hal-03313755v1
TAF4 Inactivation Reveals the 3 Dimensional Growth Promoting Activities of Collagen 6A3 Igor Martianov,Emilie Cler,Isabelle Duluc,Serge Vicaire,Muriel Philippset al. PLoS ONE, 2014, 9 (2), pp.e87365. ⟨10.1371/journal.pone.0087365⟩ Article dans une revue hal-03811643v1
CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness Bruno Pereira,Sofia Sousa,Rita Barros,Laura Carreto,Patrícia Oliveiraet al. Nucleic Acids Research, 2013, 41 (7), pp.3986 - 3999. ⟨10.1093/nar/gkt087⟩ Article dans une revue hal-02648089v1
Understanding epithelial homeostasis in the intestine: An old battlefield of ideas, recent breakthroughs and remaining controversies Jan de Mey,Jean-Noël Freund Tissue Barriers, 2013, 1 (2), pp.e24965. ⟨10.4161/tisb.24965⟩ Article dans une revue hal-03792240v1
Gastric intrinsic factor deficiency with combined GIF heterozygous mutations and FUT2 secretor variant Céline Chéry,Alain Hehn,Nadir Mrabet,Abderrahim Oussalah,Elise Jeannessonet al. Biochimie, 2013, 95 (5), pp.995-1001. ⟨10.1016/j.biochi.2013.01.022⟩ Article dans une revue hal-01474766v1
Increasing the oxygen load by treatment with myo-inositol trispyrophosphate reduces growth of colon cancer and modulates the intestine homeobox gene Cdx2 Lylia Derbal-Wolfrom,Erwan Pencreach,T Saandi,Marc Aprahamian,Elisabeth Martinet al. Oncogene, 2013, 32 (36), pp.4313-4318. ⟨10.1038/onc.2012.445⟩ Article dans une revue hal-03812783v1
Contribution of Soft Substrates to Malignancy and Tumor Suppression during Colon Cancer Cell Division Morgane Rabineau,Leyla Kocgozlu,Denis Dujardin,Bernard Senger,Youssef Haikelet al. PLoS ONE, 2013, 8 (10), pp.e78468. ⟨10.1371/journal.pone.0078468⟩ Article dans une revue hal-03807780v1
Immunolabelling of Thin Slices of Mouse Descending Colon and Jejunum Julien Bellis,Isabelle Duluc,Jean-Noël Freund,Jan de Mey Bio-protocol , 2013, 3 (20), ⟨10.21769/BioProtoc.942⟩ Article dans une revue hal-03812037v1
Regulation of the tumor suppressor homeogene Cdx2 by HNF4 alpha in intestinal cancer T Saandi,F Baraille,Lylia Derbal-Wolfrom,A Cattin,F Benahmedet al. Oncogene, 2013, 32 (32), pp.3782-3788. ⟨10.1038/onc.2012.401⟩ Article dans une revue hal-03788700v1
Directing nuclear deformation on micropillared surfaces by substrate geometry and cytoskeleton organization Florent Badique,Dimitar Stamov,Patricia Davidson,Mathieu Veuillet,Günter Reiteret al. Biomaterials, 2013, 34 (12), pp.2991-3001. ⟨10.1016/j.biomaterials.2013.01.018⟩ Article dans une revue istex hal-02584491v1
Molecular and cellular effects of vitamin B12 in brain, myocardium and liver through its role as co-factor of methionine synthase Jean-Louis Guéant,Maatem Caillerez-Fofou,Shyuefang Battaglia-Hsu,Jean-Marc Alberto,Jean-Noël Freundet al. Biochimie, 2013, 95 (5), pp.1033-1040. ⟨10.1016/j.biochi.2013.01.020⟩ Article dans une revue hal-01704564v1
Cdx2 Controls Expression of the Protocadherin Mucdhl, an Inhibitor of Growth and beta-Catenin Activity in Colon Cancer Cells Isabelle Hinkel,Isabelle Duluc,Elisabeth Martin,Dominique Guenot,Jean-Noël Freundet al. Gastroenterology, 2012, 142 (4), pp.875-885. ⟨10.1053/j.gastro.2011.12.037⟩ Article dans une revue hal-03788697v1
Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells Benjamin Renouf,Christine Soret,Thoueiba Saandi,François Delalande,Elisabeth Martinet al. Nucleic Acids Research, 2012, 40 (8), pp.3456-3469. ⟨10.1093/nar/gkr1242⟩ Article dans une revue hal-03807892v1
Gastric intestinal metaplasia revisited: function and regulation of CDX2 Rita Barros,Jean-Noël Freund,Leonor David,Raquel Almeida Trends in Molecular Medicine, 2012, 18 (9), pp.555-563. ⟨10.1016/j.molmed.2012.07.006⟩ Article dans une revue istex hal-03790027v1
The control of chromosome segregation during mitosis in epithelial cells by substrate elasticity Leyla Kocgozlu,Morgane Rabineau,Géraldine Koenig,Youssef Haikel,Pierre Schaafet al. Biomaterials, 2012, 33 (3), pp.798-809. ⟨10.1016/j.biomaterials.2011.10.024⟩ Article dans une revue istex hal-03811631v1
Identité et pathologies intestinales : le gène homéotique Cdx2 Jean-Noël Freund Annales de Pathologie, 2012, 32 (5S), pp.S24-S27. ⟨10.1016/j.annpat.2012.08.005⟩ Article dans une revue hal-03788709v1
Enteropathogenic e.coli sustains iodoacetamide-induced ulcerative colitis-like colitis in rats: modulation of IL-1β, IL-6, TNF-α, COX-2, and apoptosisi I. Abdallah Hajj Hussein,Jean-Noël Freund,Jean-Marie Reimund,A. Shams,M. Yamineet al. Journal of Biological Regulators and Homeostatic Agents, 2012, 26 (3), pp.515-526 Article dans une revue hal-03812791v1
Cdx2 determines the fate of postnatal intestinal endoderm Emma Stringer,Isabelle Duluc,Thoueiba Saandi,Irwin Davidson,Monika Bialeckaet al. Development (Cambridge, England), 2012, 139 (3), pp.465-474. ⟨10.1242/dev.070722⟩ Article dans une revue hal-03807900v1
The tumor suppressor gene APC controls planar cell polarities central to gut homeostasis. Julien Bellis,Isabelle Duluc,Béatrice Romagnolo,Christine Perret,Maree C. Fauxet al. Journal of Cell Biology, 2012, 198, pp.331-341. ⟨10.1083/jcb.201204086⟩ Article dans une revue hal-00740860v1
Immunohistochemical expression of CDX2, β-catenin, and TP53 in inflammatory bowel disease-associated colorectal cancer Camille Laurent,Magali Svrcek,Jean-François Flejou,Marie-Pierre Chenard,Bernard Ducloset al. Inflammatory Bowel Diseases, 2011, 17 (1), pp.232-240. ⟨10.1002/ibd.21451⟩ Article dans une revue hal-03811769v1
CDX2 autoregulation in human intestinal metaplasia of the stomach: impact on the stability of the phenotype Rita Barros,Luis Texeira da Mosta,Joao Pinto-De-Sousa,Isabelle Duluc,Jean-Noël Freundet al. Gut, 2011, 60 (3), pp.290-298. ⟨10.1136/gut.2010.222323⟩ Article dans une revue hal-03788698v1
Concerted involvement of Cdx / Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone Cesca van de Ven,Monika Bialecka,Roel Neijts,Teddy Young,Jennifer Rowlandet al. Development (Cambridge, England), 2011, 138 (16), pp.3451-3462. ⟨10.1242/dev.066118⟩ Article dans une revue hal-03807821v1
NADPH Oxidase 1 Modulates WNT and NOTCH1 Signaling To Control the Fate of Proliferative Progenitor Cells in the Colon Nicolas Coant,Sanae Ben Mkaddem,Eric Pedruzzi,Cécile Guichard,Xavier Trétonet al. Molecular and Cellular Biology, 2010, 30 (11), pp.2636-2650. ⟨10.1128/MCB.01194-09⟩ Article dans une revue hal-03796779v1
Pathophysiology of intestinal metaplasia of the stomach: emphasis on CDX2 regulation Rita Barros,Vânia Camilo,Bruno Pereira,Jean-Noël Freund,Leonor Davidet al. Biochemical Society Transactions, 2010, 38 (2), pp.358-363. ⟨10.1042/BST0380358⟩ Article dans une revue hal-03811611v1
CDX2 in Congenital Gut Gastric-Type Heteroplasia and Intestinal-Type Meckel Diverticula Elisabeth Martin,Marie Vanier,Manuela Tavian,Eric Guerin,Claire Domon-Dellet al. Pediatrics, 2010, 126 (3), pp.e723-e727. ⟨10.1542/peds.2009-3512⟩ Article dans une revue hal-03789463v1
Targeted Apc;twist double-mutant mice: A new model of spontaneous osteosarcoma that mimics the human disease Natacha Entz-Werlé,Philippe Choquet,Agnès Neuville,Sabine Kuchler-Bopp,François Clausset al. Translational Oncology, 2010, 3 (6), pp.344-353. ⟨10.1593/tlo.10169⟩ Article dans une revue hal-00591470v1
Anchoring secreted proteins in endoplasmic reticulum by plant oleosin: the example of vitamin B12 cellular sequestration by transcobalamin. Laurent Pons,Shyue-Fang Battaglia-Hsu,Carlos Enrique Orozco-Barrios,Sandrine Ortiou,Celine Cheryet al. PLoS ONE, 2009, 4 (7), pp.e6325. ⟨10.1371/journal.pone.0006325⟩ Article dans une revue hal-00559010v1
Intestinal Lactase as an Autologous β-Galactosidase Reporter Gene for In Vivo Gene Expression Studies Siamak Salehi,Lorna Eckley,Greta Sawyer,Xiaohong Zhang,Xuebin Donget al. Human Gene Therapy, 2009, 20 (1), pp.21-30. ⟨10.1089/hum.2008.101⟩ Article dans une revue hal-03811789v1
Cdx and Hox Genes Differentially Regulate Posterior Axial Growth in Mammalian Embryos Teddy Young,Jennifer Elizabeth Rowland,Cesca van de Ven,Monika Bialecka,Ana Novoaet al. Developmental Cell, 2009, 17 (4), pp.516-526. ⟨10.1016/j.devcel.2009.08.010⟩ Article dans une revue hal-03811755v1
Expression and localisation of insulin receptor substrate 2 in normal intestine and colorectal tumours. Regulation by intestine-specific transcription factor CDX2 S Modica,A Morgano,L Salvatore,M Petruzzelli,M-T Vanieret al. Gut, 2009, 58 (9), pp.1250-1259. ⟨10.1136/gut.2008.158386⟩ Article dans une revue hal-03813788v1
The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells Isabelle Gross,Isabelle Duluc,T. Benameur,A. Calon,Elisabeth Martinet al. Oncogene, 2008, 27 (1), pp.107-115. ⟨10.1038/sj.onc.1210601⟩ Article dans une revue hal-03812788v1
Key elements of the BMP/SMAD pathway co-localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines R Barros,B Pereira,I Duluc,M Azevedo,N Mendeset al. The Journal of pathology and bacteriology, 2008, 215 (4), pp.411-420. ⟨10.1002/path.2369⟩ Article dans une revue istex hal-03313800v1
Cdx1, a dispensable homeobox gene for gut development with limited effect in intestinal cancer C Bonhomme,A Calon,Elisabeth Martin,S Robine,A Neuvilleet al. Oncogene, 2008, 27 (32), pp.4497-4502. ⟨10.1038/onc.2008.78⟩ Article dans une revue hal-03812890v1
Differential regulation of CDX1 and CDX2 gene expression by deficiency in methyl group donors Xiaohong Lu,Jean-Noël Freund,Marc Muller,Juliette Ravey,Jean-Pierre Nicolaset al. Biochimie, 2008, 90 (5), pp.697-704. ⟨10.1016/j.biochi.2007.12.002⟩ Article dans une revue istex hal-03811802v1
Multiple Regulatory Regions Control the Complex Expression Pattern of the Mouse Cdx2 Homeobox Gene Fairouz Benahmed,Isabelle Gross,Stephen Gaunt,Felix Beck,Frédéric Jehanet al. Gastroenterology, 2008, 135 (4), pp.1238-1247.e3. ⟨10.1053/j.gastro.2008.06.045⟩ Article dans une revue hal-03811811v1
Inflammatory bowel disease in rats: Bacterial and chemical interaction Inaya Abdallah Hajj Hussein,Rania Tohme,Kassem Barada,Mostafa Hassan Mostafa,Jean-Noël Freundet al. World Journal of Gastroenterology, 2008, 14 (25), pp.4028. ⟨10.3748/wjg.14.4028⟩ Article dans une revue hal-03811622v1
The Human Mucin MUC4 Is Transcriptionally Regulated by Caudal-related Homeobox, Hepatocyte Nuclear Factors, Forkhead Box A, and GATA Endodermal Transcription Factors in Epithelial Cancer Cells Nicolas Jonckheere,Audrey Vincent,Michaël Perrais,Marie-Paule Ducourouble,Anita Korteland-van Maleet al. Journal of Biological Chemistry, 2007, ⟨10.1074/jbc.M700905200⟩ Article dans une revue hal-02905844v1
The Microenvironment Controls CDX2 Homeobox Gene Expression in Colorectal Cancer Cells Fairouz Benahmed,Isabelle Gross,Dominique Guenot,Frédéric Jehan,Elisabeth Martinet al. American Journal of Pathology, 2007, 170 (2), pp.733-744. ⟨10.2353/ajpath.2007.060696⟩ Article dans une revue hal-03788843v1
Functional interaction between the homeoprotein CDX1 and the transcriptional machinery containing the TATA-binding protein. Alexandre Calon,Isabelle Gross,Irwin Davidson,Michèle Kedinger,Isabelle Dulucet al. Nucleic Acids Research, 2007, 35 (1), pp.175-85. ⟨10.1093/nar/gkl1034⟩ Article dans une revue hal-00188312v1
Precancerous Lesions Upon Sporadic Activation of β-Catenin in Mice Isabelle Coste,Jean-Noël Freund,Simone Spaderna,Thomas Brabletz,Toufic Renno Gastroenterology, 2007, 132 (4), pp.1299-1308. ⟨10.1053/j.gastro.2007.01.029⟩ Article dans une revue hal-03045926v1
Different effects of the Cdx1 and Cdx2 homeobox genes in a murine model of intestinal inflammation A Calon,Isabelle Gross,B Lhermitte,Elisabeth Martin,F Becket al. Gut, 2007, 56 (12), pp.1688-1695. ⟨10.1136/gut.2007.125542⟩ Article dans une revue hal-03789487v1
Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival Isabelle Gross,Olivier Armant,Soufiane Benosmane,Jose-Luis Gonzalez de Aguilar,Jean-Noël Freundet al. Cell Death and Differentiation, 2007, 14 (10), pp.1802-1812. ⟨10.1038/sj.cdd.4402188⟩ Article dans une revue hal-03817466v1
Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies. Karine Buchet-Poyau,Julien Courchet,Hervé Le Hir,Bertrand Séraphin,Jean-Yves Scoazecet al. Nucleic Acids Research, 2007, 35 (4), pp.1289-300. ⟨10.1093/nar/gkm016⟩ Article dans une revue hal-00167447v1
Multiple-contrast X-ray micro-CT visualization of colon malformations and tumours in situ in living mice Philippe Choquet,Alexandre Calon,Elodie Breton,Felix Beck,Claire Domon-Dellet al. Comptes Rendus. Biologies, 2007, 330 (11), pp.821-827. ⟨10.1016/j.crvi.2007.08.002⟩ Article dans une revue istex hal-00591489v1
Frequent rearrangements and amplification of the CDX2 homeobox gene in human sporadic colorectal cancers with chromosomal instability Clément Subtil,Eric Guérin,Anne Schneider,Marie-Pierre Chenard,Elisabeth Martinet al. Cancer Letters, 2007, 247 (2), pp.197-203. ⟨10.1016/j.canlet.2006.04.004⟩ Article dans une revue istex hal-03811777v1
Bile Acids Induce Ectopic Expression of Intestinal Guanylyl Cyclase C Through Nuclear Factor-κB and Cdx2 in Human Esophageal Cells Philip Debruyne,Matthew Witek,Li Gong,Ruth Birbe,Inna Chervonevaet al. Gastroenterology, 2006, 130 (4), pp.1191-1206. ⟨10.1053/j.gastro.2005.12.032⟩ Article dans une revue hal-03812871v1
CDX-2 homeobox gene expression in human gastric carcinoma and precursor lesions Hyung-Seok Kim,Ji-Shin Lee,Jean-Noël Freund,Kyung-Whan Min,Jeong-Soo Leeet al. Journal of Gastroenterology and Hepatology, 2006, 21 (2), pp.438-442. ⟨10.1111/j.1440-1746.2005.03933.x⟩ Article dans une revue hal-03812876v1
Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation. Isabelle Gross,Benoit Lhermitte,Claire Domon-Dell,Isabelle Duluc,Elisabeth Martinet al. Oncogene, 2005, 24 (54), pp.7955-63. ⟨10.1038/sj.onc.1208945⟩ Article dans une revue inserm-00157949v1
Laminin isoforms: biological roles and effects on the intracellular distribution of nuclear proteins in intestinal epithelial cells. Natacha Turck,Isabelle Gross,Patrick Gendry,Jeanne Stutzmann,Jean-Noël Freundet al. Experimental Cell Research, 2005, 303 (2), pp.494-503. ⟨10.1016/j.yexcr.2004.10.025⟩ Article dans une revue istex inserm-00158350v1
Down-regulation of the Tumor Suppressor PTEN by the Tumor Necrosis Factor-α/Nuclear Factor-κB (NF-κB)-inducing Kinase/NF-κB Pathway Is Linked to a Default IκB-α Autoregulatory Loop Sunghoon Kim,Claire Domon-Dell,Junghee Kang,Dai Chung,Jean-Noël Freund Journal of Biological Chemistry, 2004, 279 (6), pp.4285 - 4291. ⟨10.1074/jbc.m308383200⟩ Article dans une revue hal-03789566v1
Homeodomain protein CDX2 regulates COX-2 expression in colorectal cancer Sang-Pyo Kim,Jong-Wook Park,Sung-Hee Lee,Jun Hee Lim,Byeong-Churl Janget al. Biochemical and Biophysical Research Communications, 2004, 315 (1), pp.93-99. ⟨10.1016/j.bbrc.2004.01.020⟩ Article dans une revue istex hal-03811713v1
Control of differentiation-induced calbindin-D 9k gene expression in Caco-2 cells by cdx-2 and HNF-1α Liyong Wang,Anna Klopot,Jean-Noel Freund,Jean-Noël Freund,Lauren Dowlinget al. AJP - Gastrointestinal and Liver Physiology, 2004, 287 (5), pp.G943-G953. ⟨10.1152/ajpgi.00121.2004⟩ Article dans une revue hal-03789475v1
SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes. Philippe Blache,Marc van de Wetering,Isabelle Duluc,Claire Domon,Philippe Bertaet al. Journal of Cell Biology, 2004, 166 (1), pp.37-47. ⟨10.1083/jcb.200311021⟩ Article dans une revue hal-00266987v1
Klotho Is a Novel β-Glucuronidase Capable of Hydrolyzing Steroid β-Glucuronides Osamu Tohyama,Akihiro Imura,Akiko Iwano,Jean-Noël Freund,Bernard Henrissatet al. Journal of Biological Chemistry, 2004, 279 (11), pp.9777 - 9784. ⟨10.1074/jbc.m312392200⟩ Article dans une revue hal-03792399v1
Down-Regulation of the Homeodomain Factor Cdx2 in Colorectal Cancer by Collagen Type I Thomas Brabletz,Simone Spaderna,Jochen Kolb,Falk Hlubek,Gerhard Falleret al. Cancer Research, 2004, 64 (19), pp.6973-6977. ⟨10.1158/0008-5472.CAN-04-1132⟩ Article dans une revue hal-03813556v1
Cdx1 homeobox gene during human colon cancer progression Claire Domon-Dell,Anne Schneider,Virginie Moucadel,Eric Guerin,Dominique Guenotet al. Oncogene, 2003, 22 (39), pp.7913-7921. ⟨10.1038/sj.onc.1206756⟩ Article dans une revue hal-03812880v1
Differential regulation of the glucose-6-phosphatase TATA box by intestine-specific homeodomain proteins CDX1 and CDX2 Amandine Gautier-Stein,Claire Domon-Dell,Alexandre Calon,Isabelle Baly,Jean-Noël Freundet al. Nucleic Acids Research, 2003, 31 (18), pp.5238-5246. ⟨10.1093/nar/gkg747⟩ Article dans une revue hal-03813522v1
Cancer colorectal au cours de la rectocolite hémorragique Jean-Marie Reimund,Camille Laurent,Marie Pierrette Chenard,Jean-Pierre Bellocq,Jean-Noël Freundet al. Hépato-Gastro, 2003, 6 (10), pp.415-423 Article dans une revue hal-03812785v1
The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development C Bonhomme,Isabelle Duluc,E Martin,K Chawengsaksophak,Marie Pierrette Chenardet al. Gut, 2003, 52 (10), pp.1465-1471. ⟨10.1136/gut.52.10.1465⟩ Article dans une revue hal-03797013v1
Endoderm- and mesenchyme-dependent commitment of the differentiated epithelial cell types in the developing intestine of rat Christelle Ratineau,Isabelle Duluc,Céline Pourreyron,Michèle Kedinger,Jean-Noël Freundet al. Differentiation, 2003, 71 (2), pp.163-169. ⟨10.1046/j.1432-0436.2003.t01-1-710203.x⟩ Article dans une revue hal-03813756v1
Stimulation of the intestinal Cdx2 homeobox gene by butyrate in colon cancer cells Claire Domon-Dell,Q Wang,S Kim,Michèle Kedinger,B M Everset al. Gut, 2002, 50 (4), pp.525-529. ⟨10.1136/gut.50.4.525⟩ Article dans une revue hal-03796863v1
Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway Eek-Hoon Jho,Tong Zhang,Claire Domon,Choun-Ki Joo,Jean-Noël Freundet al. Molecular and Cellular Biology, 2002, 22 (4), pp.1172-1183. ⟨10.1128/MCB.22.4.1172-1183.2002⟩ Article dans une revue hal-03788855v1
The homeobox gene Cdx1 belongs to the p53-p21(WAF)-Bcl-2 network in intestinal epithelial cells Virginie Moucadel,Maria Serena Totaro,Claire Domon-Dell,Philippe Soubeyran,Jean Charles Dagornet al. Biochemical and Biophysical Research Communications, 2002, 297 (3), pp.607-615. ⟨10.1016/s0006-291x(02)02250-7⟩ Article dans une revue istex hal-03812793v1
Stimulation of Cdx1 by oncogenic β-catenin/Tcf4 in colon cancer cells; opposite effect of the CDX2 homeoprotein Claire Domon-Dell,Jean-Noël Freund FEBS Letters, 2002, 518 (1-3), pp.83-87. ⟨10.1016/s0014-5793(02)02650-9⟩ Article dans une revue hal-03791635v1
PTEN and TNF-α regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-κB–dependent pathway Sunghoon Kim,Claire Domon-Dell,Qingding Wang,Dai Chung,Antonio Di Cristofanoet al. Gastroenterology, 2002, 123 (4), pp.1163-1178. ⟨10.1053/gast.2002.36043⟩ Article dans une revue hal-03817213v1
Functional Interference between Thyroid Hormone Receptor α (TRα) and Natural Truncated TRΔα Isoforms in the Control of Intestine Development Michelina Plateroti,Karine Gauthier,Claire Domon-Dell,Jean-Noël Freund,Jacques Samarutet al. Molecular and Cellular Biology, 2001, 21 (14), pp.4761-4772. ⟨10.1128/MCB.21.14.4761-4772.2001⟩ Article dans une revue hal-03791255v1
Differentially expressed endoderm and mesenchyme genes along the fetal rat intestine Isabelle Duluc,C. Hoff,Michèle Kedinger,Jean-Noël Freund Genesis - The Journal of Genetics and Development, 2001, 29 (2), pp.55-59 Article dans une revue hal-03812797v1
Aspects cellulaires et molécuaires du développemet intestinal Jean-Noël Freund Hépato-Gastro, 2000, 1 (7), pp.47-56 Article dans une revue hal-03814378v1
Wnt/(beta)-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine H. Lickert,Claire Domon,G. Huls,C. Wehrle,Isabelle Dulucet al. Development (Cambridge, England), 2000, 127 (17), pp.3805-3813 Article dans une revue hal-03812792v1
Promotion of intestinal carcinogenesis by dietary methionine B. Duranton,Jean-Noël Freund,M. Galluser,R. Schleiffer,F. Gosséet al. Carcinogenesis, 1999, 20 (3), pp.493-497 Article dans une revue hal-03812799v1
Production of low-lactose milk by ectopic expression of intestinal lactase in the mouse mammary gland Bernard Jost,Jean-Luc Vilotte,Isabelle Duluc,Jean-Luc Rodeau,Jean-Noël Freund Nature Biotechnology, 1999, 17, pp.160-164 Article dans une revue hal-02696428v1
Downregulation of the colon tumour-suppressor homeobox gene Cdx-2 by oncogenic ras Olivier Lorentz,Axelle Cadoret,Isabelle Duluc,Jacqueline Capeau,Christian Gespachet al. Oncogene, 1999, 18 (1), pp.87-92. ⟨10.1038/sj.onc.1202280⟩ Article dans une revue hal-03812197v1
Involvement of T3Rα- and β-receptor subtypes in mediation of T3 functions during postnatal murine intestinal development☆, ☆☆, ★ Michelina Plateroti,Olivier Chassande,Alexandre Fraichard,Karine Gauthier,Jean-Noël Freundet al. Gastroenterology, 1999, 116 (6), pp.1367-1378. ⟨10.1016/S0016-5085(99)70501-9⟩ Article dans une revue istex hal-03818728v1
Prédigestion d'un composant du lait, le lactose, dans la glande mammaire Jean-Noël Freund Médecine/Sciences, 1999, 15 (8-9), pp.1058-1059. ⟨10.4267/10608/1487⟩ Article dans une revue hal-03817261v1
Cellular and molecular partners involved in gut morphogenesis and differentiation Michèle Kedinger,O. Lefebvre,Isabelle Duluc,Jean-Noël Freund,Patricia Simon-Assmann Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (1934–1990), 1998, 353 (1370), pp.847-856. ⟨10.1098/rstb.1998.0249⟩ Article dans une revue hal-03813452v1
The Cdx-1 and Cdx-2 homeobox genes in the intestine Jean-Noël Freund,Claire Domon-Dell,Michèle Kedinger,Isabelle Duluc Biochemistry and Cell Biology, 1998, 76 (6), pp.957-969. ⟨10.1139/o99-001⟩ Article dans une revue hal-03817632v1
Subepithelial fibroblast cell lines from different levels of gut axis display regional characteristics Michelina Plateroti,D. C. Rubin,Isabelle Duluc,R. Singh,C. Foltzer-Jourdainneet al. American Journal of Physiology, 1998, 274 (5 Pt 1) Article dans une revue hal-03812790v1
Lactase is unchanged in suckling mice fed with lactose-free milk Bernard Jost,Isabelle Duluc,Jean-Luc Vilotte,Jean-Noël Freund Gastroentérologie Clinique et Biologique / Research and Clinics in Hepatology and Gastroenterology, 1998, 22, pp.863-867 Article dans une revue hal-02690133v1
Intestinal Epithelial-Mesenchymal Cell Interactions Michèle Kedinger,Isabelle Duluc,C. Fritsch,O. Lorentz,M. Platerotiet al. Annals of the New York Academy of Sciences, 1998, 859 (1 INTESTINAL PL), pp.1-17. ⟨10.1111/j.1749-6632.1998.tb11107.x⟩ Article dans une revue hal-03814869v1
Functional diversity and interactions between the repeat domains of rat intestinal lactase Bernard Jost,Isabelle Duluc,Melville Richardson,Richard Lathe,Jean-Noël Freund Biochemical Journal, 1997, 327 (1), pp.95-103. ⟨10.1042/bj3270095⟩ Article dans une revue hal-03791201v1
Key Role of the Cdx2 Homeobox Gene in Extracellular Matrix–mediated Intestinal Cell Differentiation Olivier Lorentz,Isabelle Duluc,Adèle De Arcangelis,Patricia Simon-Assmann,Michèle Kedingeret al. Journal of Cell Biology, 1997, 139 (6), pp.1553-1565. ⟨10.1083/jcb.139.6.1553⟩ Article dans une revue hal-03791318v1
Identification of homologues of the mammalian intestinal lactase gene in non-mammals (birds and molluscs) Jean-Noël Freund,Bernard Jost,Olivier Lorentz,Isabelle Duluc Biochemical Journal, 1997, 322 (2), pp.491-498. ⟨10.1042/bj3220491⟩ Article dans une revue hal-03791310v1
Mesenchyme-mediated effects of retinoic acid during rat intestinal development M. Plateroti,Jean-Noël Freund,C. Leberquier,Michèle Kedinger Journal of Cell Science, 1997, 110 ( Pt 10), pp.1227-1238 Article dans une revue hal-03812798v1
Changing intestinal connective tissue interactions alters homeobox gene expression in epithelial cells Isabelle Duluc,Olivier Lorentz,Christine Fritsch,Cathy Leberquier,Michèle Kedingeret al. Journal of Cell Science, 1997, 110 ( Pt 11), pp.1317-1324. ⟨10.1242/jcs.110.11.1317⟩ Article dans une revue hal-03812787v1
Verification of the lactase site of rat lactase-phlorizin hydrolase by site-directed mutagenesis Adriana Neele,Alexandra W.C. Einerhand,Jan Dekker,Hans Büller,Jean-Noël Freundet al. Gastroenterology, 1995, 109 (4), pp.1234-1240. ⟨10.1016/0016-5085(95)90583-9⟩ Article dans une revue hal-03812281v1
Activity of the rat lactase gene promoter in transfected human colon cancer cells R. Boukamel,P. Neuville,Isabelle Duluc,Jean-Noël Freund Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie, 1995, 318 (11), pp.1133-1140 Article dans une revue hal-03814373v1
Ultrastructural study of intestinal lactase gene expression Jean-Noël Freund,Bernard Jost,Isabelle Duluc,G. Morel Biology of the Cell, 1995, 83 (2-3), pp.211-217 Article dans une revue hal-03812800v1
The cis -element CE-LPH1 of the rat intestinal lactase gene promoter interacts in vitro with several nuclear factors present in endodermal tissues Rita Boukamel,Jean-Noël Freund FEBS Letters, 1994, 353 (1), pp.108-112. ⟨10.1016/0014-5793(94)01026-9⟩ Article dans une revue hal-03788837v1
Fetal endoderm primarily holds the temporal and positional information required for mammalian intestinal development. Isabelle Duluc,Jean-Noël Freund,C Leberquier,Michèle Kedinger Journal of Cell Biology, 1994, 126 (1), pp.211-221. ⟨10.1083/jcb.126.1.211⟩ Article dans une revue hal-03789578v1
Precocious and reversible expression of sucrase-isomaltase unrelated to intestinal cell turnover E. Nsi-Emvo,C. Foltzer-Jourdainne,Francis Raul,F. Gosse,Isabelle Dulucet al. AJP - Gastrointestinal and Liver Physiology, 1994, 266 (4), pp.G568-G575. ⟨10.1152/ajpgi.1994.266.4.G568⟩ Article dans une revue hal-03812230v1
Multiple levels of control of the stage- and region-specific expression of rat intestinal lactase. Isabelle Duluc,Bernard Jost,Jean-Noël Freund Journal of Cell Biology, 1993, 123 (6), pp.1577-1586. ⟨10.1083/jcb.123.6.1577⟩ Article dans une revue hal-03792443v1
The rat LPH Gene 5′ region: comparative structure with the human gene Rita Boukamel,Jean-Noël Freund DNA Sequence, 1992, 3 (2), pp.119-121. ⟨10.3109/10425179209034006⟩ Article dans une revue hal-03817641v1
Gradient expression of Cdx along the rat intestine throughout postnatal development Jean-Noël Freund,Rita Boukamel,Aziz Benazzouz FEBS Letters, 1992, 314 (2), pp.163-166. ⟨10.1016/0014-5793(92)80965-j⟩ Article dans une revue hal-03788821v1
Dietary control of the lactase mRNA distribution along the rat small intestine Isabelle Duluc,M. Galluser,Francis Raul,Jean-Noël Freund American Journal of Physiology, 1992, 262 (6 Pt 1) Article dans une revue hal-03814382v1
Do co-translated product(s) of lactase-phlorizin hydrolase accumulate in the rat intestine? Jean-Noël Freund Cellular and Molecular Biology, 1992, 38 (7), pp.713-718 Article dans une revue hal-03814375v1
Rat lactase activity and mRNA expression in relation to the thyroid and corticoid status Jean-Noël Freund,C. Foltzer-Jourdainne,Isabelle Duluc,M. Galluser,F. Gosseet al. Cellular and Molecular Biology, 1991, 37 (4), pp.463-466 Article dans une revue hal-03818491v1
Derivatives of Plant Beta-GIucans Are Hydrolyzed by Intestinal Lactase-Phlorizin Hydrolase of Mammals Jean-Noël Freund,Francine Gossé Enzyme Protein, 1991, 45 (1-2), pp.71-74. ⟨10.1159/000468868⟩ Article dans une revue hal-03813472v1
Sequence of the precursor of intestinal lactase-phlorizin hydrolase from fetal rat Isabelle Duluc,Rita Boukamel,Ned Mantei,Giorgio Semenza,Francis Raulet al. Gene, 1991, 103 (2), pp.275-276. ⟨10.1016/0378-1119(91)90286-K⟩ Article dans une revue hal-03817319v1
Adaptation of intestinal hydrolases to starvation in rats: effect of thyroid function M. Galluser,R. Belkhou,Jean-Noël Freund,Isabelle Duluc,N. Torpet al. Journal of Comparative Physiology B, 1991, 161 (4), pp.357-361. ⟨10.1007/BF00260793⟩ Article dans une revue istex hal-03812789v1
Lactase expression is controlled differently in the jejunum and ileum during development in rats Jean-Noël Freund,Francis Raul,Isabelle Duluc Gastroenterology, 1991, 100 (2), pp.388-394. ⟨10.5555/uri:pii:0016508591902072⟩ Article dans une revue hal-03818483v1
Type IV collagen mRNA accumulates in the mesenchymal compartment at early stages of murine developing intestine. P Simon-Assmann,F Bouziges,Jean-Noël Freund,F Perrin-Schmitt,Michèle Kedinger Journal of Cell Biology, 1990, 110 (3), pp.849-857. ⟨10.1083/jcb.110.3.849⟩ Article dans une revue hal-03788848v1
Different expression of the mRNA detected by the cDNA for fetal rat lactase in the jejunum and colon Isabelle Duluc,Jean-Noël Freund,N. Mantei,Francis Raul Gastroentérologie Clinique et Biologique / Research and Clinics in Hepatology and Gastroenterology, 1990, 14 (8-9), pp.635-640 Article dans une revue hal-03817670v1
Specific expression of lactase in the jejunum and colon during postnatal development and hormone treatments in the rat Jean-Noël Freund,Isabelle Duluc,C Foltzer-Jourdainne,F Gosse,Francis Raul Biochemical Journal, 1990, 268 (1), pp.99-103. ⟨10.1042/bj2680099⟩ Article dans une revue hal-03796808v1
Comparative expression of the mRNA for three intestinal hydrolases during postnatal development in the rat Jean-Noël Freund,N. Torp,Isabelle Duluc,C. Foltzer-Jourdainne,M. Danielsenet al. Cellular and Molecular Biology, 1990, 36 (6), pp.729-736 Article dans une revue hal-03814379v1
Discrepancy between the intestinal lactase enzymatic activity and mRNA accumulation in sucklings and adults Effect of starvation and thyroxine treatment Jean-Noël Freund,Isabelle Duluc,Francis Raul FEBS Letters, 1989, 248 (1-2), pp.39-42. ⟨10.1016/0014-5793(89)80427-2⟩ Article dans une revue hal-03790118v1
The gene for intestinal sucrase-isomaltase as member of a gene family Jean-Noël Freund,R. Heilig,N. Lehner,Francis Raul Cellular and Molecular Biology, 1989, 35 (3), pp.313-324 Article dans une revue hal-03818484v1
Synthetic probes to investigate the genetic arrangement of the coding sequences involved in the pyrimidine pathway over the phylogenesis Jean-Noël Freund,Bruno Jarry Life Science Advance Molecular Genetics, 1988, 7, pp.1-5 Article dans une revue hal-03812795v1
The rudimentary gene of Drosophila melanogaster encodes four enzymic functions Jean-Noël Freund,B.P. Jarry Journal of Molecular Biology, 1987, 193 (1), pp.1-13. ⟨10.1016/0022-2836(87)90621-8⟩ Article dans une revue hal-03817643v1
Molecular organization of the rudimentary gene of Drosophila melanogaster Jean-Noël Freund,W. Vergis,P. Schedl,B.P. Jarry Journal of Molecular Biology, 1986, 189 (1), pp.25-36. ⟨10.1016/0022-2836(86)90378-5⟩ Article dans une revue hal-03817199v1
Organization of transcription units around the Drosophila melanogaster rudimentary locus and temporal pattern of expression J. Rawls,Jean-Noël Freund,B. Jarry,C. Louis,W. Segraveset al. Molecular and General Genetics MGG, 1986, 202 (3), pp.493-499. ⟨10.1007/BF00333283⟩ Article dans une revue hal-03817202v1

Communication dans un congrès (8)

Tu1986 The Cadherin-Related Mucdhl Is Decreased in Stem Cell-Like Colon Tumors and Inhibits β-Catenin Signaling in a Non-Classical Way Mathilde Baranger,Georg Mellitzer,Laetitia Marisa,Elisabeth Martin,Isabelle Dulucet al. DDW2015, Digestive Disease Week, Washington, USA, 16-19 Mai 2015, May 2015, Washington, United States. pp.S-953, ⟨10.1016/S0016-5085(15)33252-2⟩ Communication dans un congrès hal-04801235v1
Mucdhl, a typical cadherin that decreases in type from colon &quot;cancer stem cell&quot; and inhibits the beta-catenin of unconventional way M. Baranger,Georg Mellitzer,L Marisa,Elisabeth Martin,Isabelle Dulucet al. 2ème Congrès de la SFC, Société Française du Cancer, Jun 2015, Paris, France. pp.127-128 Communication dans un congrès hal-04801443v1
New Insight in Inflammatory Bowel Disease Pathophysiology: Current and Future Therapeutic Applications Jean-Marie Reimund,Jean-Noël Freund,Bernard Duclos American Association of Anatomist; Annual Meeting 2015, Mar 2015, Boston, United States Communication dans un congrès hal-04801669v1
Divisions asymmetric with regard to cell fate and mNumb contribute to lineage specification in mouse colon crypts Jan de Mey,Jean-Noël Freund Intestinal Stem Cells. New concepts and methods. CHU Purpan, Toulouse, 21 novembre 2013, Nov 2013, Toulouse, France Communication dans un congrès hal-04803748v1
Evidence for non-hematopoietic Cre activity in Pf4-Cre mice Fabien Pertuy,Catherine Strassel,Anita Eckly,Jean-Noël Freund,Isabelle Dulucet al. XXIV Congress of the ISTH, International Society on Thrombosis and Haemostasis, Jun 2013, Amsterdam, Netherlands Communication dans un congrès hal-04801261v1
P003 Selective inhibition of eIF2alpha dephosphorylation prevents colitis and shows therapeutic potential in a new model of ulcerative colitis X. Treton,E. Pedruzzi,C. Guichard,M. Vallee,S. Sedghiet al. DDW2013, Digestive Disease Week, May 2013, Orlando, United States. pp.S12, ⟨10.1016/S1873-9946(13)60026-4⟩ Communication dans un congrès hal-04801558v1
Su1866 The CDx2 Homeoprotein Inhibits DNA Repair by Non-Homologous End Joining Specifically in Colon Cancer but Not in Leukemia Cells Benjamin Renouf,Christine Soret,Thoueiba Saandi,François Delalande,Elisabeth Martinet al. DDW2012, Digestive Disease Week, May 2012, San Diego, United States. pp.S-522, ⟨10.1016/s0016-5085(12)62005-8⟩ Communication dans un congrès hal-03811655v1
Levels and Factors of Control of Small-Intestinal Lactase Expression in the Laboratory Rat Jean-Noël Freund,R. Boukamel,Isabelle Duluc 2nd International Symposium on Common Food Intolerances: Health Risks due to Lack or Consumption of Milk in Human Nutrition and Adult-Type Hypolactasia, Capri, October 1992, Oct 1992, Capri, Italy Communication dans un congrès hal-03818485v1

Chapitre d'ouvrage (7)

Inflammatory Bowel Disease-Associated Cancer Jean-Marie Reimund,Jean-Noël Freund Encyclopedia of Cancer, Springer Berlin Heidelberg, pp.2258-2263, 2017, ⟨10.1007/978-3-662-46875-3_3046⟩ Chapitre d'ouvrage hal-03812029v1
Ulcerative Colitis-Associated Colorectal Cancer Prevention by 5-Aminosalicylates: Current Status and Perspectives Jean-Marie Reimund,Marion Tavernier,Stephanie Viennot,Inaya Abdallah Hajj Hussein,Benoit Dupontet al. Ulcerative Colitis from Genetics to Complications, InTech, 2012, ⟨10.5772/25577⟩ Chapitre d'ouvrage hal-02461233v1
Inflammatory Bowel Disease-associated Cancer Jean-Marie Reimund,Jean-Noël Freund Manfred Schwab. Encyclopedia of Cancer, Springer Berlin Heidelberg, pp.1525-1528, 2008, 978-3-540-36847-2 Chapitre d'ouvrage hal-03814374v1
Cell interactions through the basement membrane in intestinal development and differentiation Michèle Kedinger,Jean-Noël Freund,J. F. Launay,Patricia Simon-Assmann,I. R. Sandersonet al. Development of the gastrointestinal tract, pp.83-102, 2000 Chapitre d'ouvrage hal-03814377v1
Homeobox genes and intestinal development Claire Domon-Dell,Isabelle Duluc,Michèle Kedinger,Jean-Noël Freund Cytokines and Cell Homeostasis in the Gastroinstestinal Tract, 113, Springer, pp.72-81, 2000, 978-0-7923-8758-9 Chapitre d'ouvrage hal-03812794v1
Regulation of the epithelial-mesenchymal cross-talk in the gut Michèle Kedinger,J. Olsen,C. Fritsch,Patricia Simon-Assmann,Jean-Noël Freund Intestinal Mucosa and its Diseases - Pathophysiology and Clinics, 110, Springer, 1999, 978-0-7923-8754-1 Chapitre d'ouvrage hal-03812796v1
Cellular and molecular mechanisms regulating intestinal development Michèle Kedinger,M. Plateroti,V. Orian-Rousseau,O. Lorentz,C. Fritschet al. Cellular and molecular mechanisms regulating intestinal development, 94, Springer, 1997, 978-0-7923-8726-8 Chapitre d'ouvrage hal-03814376v1

Autre publication scientifique (1)

Gut epithelium Michèle Kedinger,Jean-Noël Freund Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine, 2005, pp.736-739 Autre publication scientifique hal-03812786v1