Gaël NICOLAS

https://cvscience.aviesan.fr/cv/76/gael-nicolas
30
Documents
Identifiants chercheurs

Présentation


Publications

Publications

Deposit thumbnail

Regulation of Aldosterone Secretion by Substance P and the Neurokinin Type 1 Receptor in Aldosterone‐Producing Adenomas

Antoine‐guy Lopez , Céline Duparc , Sylvie Renouf , Margot D’agostino , Kelly de Sousa et al.

Journal of the American Heart Association, 2026, ⟨10.1161/JAHA.125.045539⟩

Article dans une revue hal-05458279v1
Deposit thumbnail

Revealing the impact of partial gene duplications in ASH1L: integration of optical genome mapping and RNA sequencing

Grégoire Blavier , François Lecoquierre , Anne-Marie Guerrot , Géraldine Joly Hélas , Stéphane Rondeau et al.

Molecular Cytogenetics, 2025, ⟨10.1186/s13039-025-00740-5⟩

Article dans une revue hal-05408693v1
Deposit thumbnail

Domain mapping of disease mutations reveals pathogenic SORL1 variants in Alzheimer’s disease

Olav Andersen , Matthijs de Waal , Giulia Monti , Niccolo Tesi , Anne Mette G. Jensen et al.

Molecular Neurodegeneration, 2025, 20 (1), pp.122. ⟨10.1186/s13024-025-00907-z⟩

Article dans une revue hal-05406809v1
Deposit thumbnail

Soluble SorLA in CSF, a novel biomarker to explore disrupted trafficking of SorLA protein in Alzheimer disease

Romain Castelot , Aline Zarea , David Wallon , Anne Rovelet-Lecrux , Catherine Schramm et al.

Alzheimer's Research and Therapy, 2025, 17 (1), pp.100. ⟨10.1186/s13195-025-01748-0⟩

Article dans une revue hal-05060515v1
Deposit thumbnail

Amyloid-β peptide signature associated with cerebral amyloid angiopathy in familial Alzheimer’s disease with APPdup and Down syndrome

Amal Kasri , Elena Camporesi , Eleni Gkanatsiou , Susana Boluda , Gunnar Brinkmalm et al.

Acta Neuropathologica, 2024, 148 (1), pp.8. ⟨10.1007/s00401-024-02756-4⟩

Article dans une revue hal-05387918v1
Deposit thumbnail

The microbiota and the host organism switch between cooperation and competition based on dietary iron levels

Marie-Louise Noordine , Yohannes Seyoum , Aurélia Bruneau , Kaleab Baye , Thibaud Lefebvre et al.

Gut microbes, 2024, 16 (1), pp.2361660. ⟨10.1080/19490976.2024.2361660⟩

Article dans une revue hal-04645842v1

Prenatal Alcohol Exposure Impairs the Placenta–Cortex Transcriptomic Signature, Leading to Dysregulation of Angiogenic Pathways

Camille Sautreuil , Maryline Lecointre , Céline Derambure , Carole Brasse-Lagnel , Philippe Leroux et al.

International Journal of Molecular Sciences, 2023, 24 (17), pp.13484. ⟨10.3390/ijms241713484⟩

Article dans une revue hal-05251923v1
Deposit thumbnail

Whole Exome/Genome Sequencing Joint Analysis of a Family with Oligogenic Familial Hypercholesterolemia

Youmna Ghaleb , Sandy Elbitar , Anne Philippi , Petra El Khoury , Yara Azar et al.

Metabolites, 2022, 12 (3), pp.262. ⟨10.3390/metabo12030262⟩

Article dans une revue hal-03642664v1
Deposit thumbnail

ABCB6 Polymorphisms are not Overly Represented in Patients with Porphyria

Colin P Farrell , Gaël Nicolas , Robert Desnick , Charles J Parker , Jerome Lamoril et al.

Blood Advances, 2022, 6 (3), pp.760-766. ⟨10.1182/bloodadvances.2021005484⟩

Article dans une revue hal-03483658v2
Deposit thumbnail

Inherited glycosylphosphatidylinositol defects cause the rare Emm-negative blood phenotype and developmental disorders

Romain Duval , Gaël Nicolas , Alexandra Willemetz , Yoshiko Murakami , Mahmoud Mikdar et al. Article dans une revue hal-04974113v1
Deposit thumbnail

Phlebotomy as an efficient long-term treatment of congenital erythropoietic porphyria

Arienne Mirmiran , Antoine Poli , Cecile Ged , Caroline Schmitt , Thibaud Lefebvre et al.

Haematologica, In press, pp.haematol.2019.228270. ⟨10.3324/haematol.2019.228270⟩

Article dans une revue inserm-02441267v1
Deposit thumbnail

αII‐spectrin controls calcium‐regulated exocytosis in neuroendocrine chromaffin cells through N-WASP interaction

Sébastien Houy , Gaël Nicolas , Fanny Momboisse , Magali Malacombe , Marie-France Bader et al.

IUBMB Life, 2020, 72 (4), pp.544-552. ⟨10.1002/iub.2217⟩

Article dans une revue hal-02922314v1
Deposit thumbnail

Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation

Nathan Rainey , Aoula Moustapha , Ana Saric , Gaël Nicolas , Franck Sureau et al.

Cell Death Discovery, 2019, 5, ⟨10.1038/s41420-019-0234-y⟩

Article dans une revue hal-03031432v1

Regulation and tissue-specific expression of δ-aminolevulinic acid synthases in non-syndromic sideroblastic anemias and porphyrias

Katell Peoc'H , Gaël Nicolas , Caroline Schmitt , Arienne Mirmiran , Raed Daher et al.

Molecular Genetics and Metabolism, 2019, ⟨10.1016/j.ymgme.2019.01.015⟩

Article dans une revue hal-02351175v1

Regulation and tissue-specific expression of δ-aminolevulinic acid synthases in non-syndromic sideroblastic anemias and porphyrias

Katell Peoc'H , Gaël Nicolas , Caroline Schmitt , Arienne Mirmiran , Raed Daher et al.

Molecular Genetics and Metabolism, 2019, ⟨10.1016/j.ymgme.2019.01.015⟩

Article dans une revue inserm-02075450v1

Erythroid-Progenitor-Targeted Gene Therapy Using Bifunctional TFR1 Ligand-Peptides in Human Erythropoietic Protoporphyria

Arienne Mirmiran , Caroline Schmitt , Thibaud Lefebvre , Hana Manceau , Raed Daher et al.

American Journal of Human Genetics, 2019, 104 (2), pp.341-347. ⟨10.1016/j.ajhg.2018.12.021⟩

Article dans une revue hal-02328937v1
Deposit thumbnail

Lack of the multidrug transporter MRP4/ABCC4 defines the PEL-negative blood group and impairs platelet aggregation

Slim Azouzi , Mahmoud Mikdar , Patricia Hermand , Emilie-Fleur Gautier , Virginie Salnot et al.

Blood, 2019, 135 (6), pp.441-448. ⟨10.1182/blood.2019002320⟩

Article dans une revue hal-02416860v1

From a dominant to an oligogenic model of inheritance with environmental modifiers in acute intermittent porphyria

Hugo Lenglet , Caroline Schmitt , Thomas Grange , Hana Manceau , Narjesse Karboul et al.

Human Molecular Genetics, 2018, 27 (7), pp.1164-1173. ⟨10.1093/hmg/ddy030⟩

Article dans une revue hal-02351445v1
Deposit thumbnail

Mutation in human CLPX elevates levels of δ- aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria

Yvette Yien , Sarah Ducamp , Lisa van Der Vorm , Julia Kardon , Hana Manceau et al.

Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (38), pp.E8045-E8052. ⟨10.1073/pnas.1700632114⟩

Article dans une revue inserm-02075468v1
Deposit thumbnail

Inactive matriptase-2 mutants found in IRIDA patients still repress hepcidin in a transfection assay despite having lost their serine protease activity.

Flavia Guillem , Caroline Kannengiesser , Claire Oudin , Anne Lenoir , Pavle Matak et al.

Human Mutation, 2012, 33 (9), pp.1388-96. ⟨10.1002/humu.22116⟩

Article dans une revue inserm-00748562v1
Deposit thumbnail

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6.

Anne Lenoir , Jean-Christophe Deschemin , Léon Kautz , Andrew J. Ramsay , Marie-Paule Roth et al.

Blood, 2011, 117 (2), pp.647-50. ⟨10.1182/blood-2010-07-295147⟩

Article dans une revue inserm-00552073v1
Deposit thumbnail

L'hepcidine, le chef d'orchestre de l'homéostasie du fer

Gaël Nicolas

Diabète et Obésité, 2009, 4 (29), pp.94-98

Article dans une revue inserm-00378204v1
Deposit thumbnail

A mutant alphaII-spectrin designed to resist calpain and caspase cleavage questions the functional importance of this process in vivo.

Fleur Meary , Sylvain Metral , Chrystophe Ferreira , Dominique Eladari , Yves Colin et al.

Journal of Biological Chemistry, 2007, 282 (19), pp.14226-14237

Article dans une revue inserm-00284621v1
Deposit thumbnail

Tyrosine phosphorylation regulates alpha II spectrin cleavage by calpain.

Gaël Nicolas , Catherine M. Fournier , Colette Galand , Laurence Malbert-Colas , Odile Bournier et al.

Molecular and Cellular Biology, 2002, 22 (10), pp.3527-3536

Article dans une revue inserm-00284770v1
Deposit thumbnail

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice.

Gaël Nicolas , Myriam Bennoun , Isabelle Devaux , Carole Beaumont , Bernard Grandchamp et al.

Proceedings of the National Academy of Sciences of the United States of America, 2001, 98 (15), pp.8780-5. ⟨10.1073/pnas.151179498⟩

Article dans une revue inserm-00331349v1
Deposit thumbnail

Spectrin self-association site: characterization and study of beta-spectrin mutations associated with hereditary elliptocytosis.

Gaël Nicolas , Sophie Pedroni , Catherine M. Fournier , Huguette Gautero , Constantin T. Craescu et al.

Biochemical Journal, 1998, 332 ( Pt 1), pp.81-9

Article dans une revue inserm-00284779v1