Gaël NICOLAS https://cvscience.aviesan.fr/cv/76/gael-nicolas

Identifiants chercheurs

IdHAL :

gael-nicolas

ORCID :

0000-0002-1671-8274

IdRef :

08351483X

Présentation

http://cvscience.aviesan.fr/cv/76/gael-nicolas

Publications

Article dans une revue (26)

Regulation of Aldosterone Secretion by Substance P and the Neurokinin Type 1 Receptor in Aldosterone‐Producing Adenomas Antoine‐guy Lopez,Céline Duparc,Sylvie Renouf,Margot D’agostino,Kelly de Sousaet al. Journal of the American Heart Association, 2026, ⟨10.1161/JAHA.125.045539⟩ Article dans une revue hal-05458279v1
Domain mapping of disease mutations reveals pathogenic SORL1 variants in Alzheimer’s disease Olav Andersen,Matthijs de Waal,Giulia Monti,Niccolo Tesi,Anne Mette G. Jensenet al. Molecular Neurodegeneration, 2025, 20 (1), pp.122. ⟨10.1186/s13024-025-00907-z⟩ Article dans une revue hal-05406809v1
Revealing the impact of partial gene duplications in ASH1L: integration of optical genome mapping and RNA sequencing Grégoire Blavier,François Lecoquierre,Anne-Marie Guerrot,Géraldine Joly Hélas,Stéphane Rondeauet al. Molecular Cytogenetics, 2025, ⟨10.1186/s13039-025-00740-5⟩ Article dans une revue hal-05408693v1
Soluble SorLA in CSF, a novel biomarker to explore disrupted trafficking of SorLA protein in Alzheimer disease Romain Castelot,Aline Zarea,David Wallon,Anne Rovelet-Lecrux,Catherine Schrammet al. Alzheimer's Research and Therapy, 2025, 17 (1), pp.100. ⟨10.1186/s13195-025-01748-0⟩ Article dans une revue hal-05060515v1
The microbiota and the host organism switch between cooperation and competition based on dietary iron levels Marie-Louise Noordine,Yohannes Seyoum,Aurélia Bruneau,Kaleab Baye,Thibaud Lefebvreet al. Gut microbes, 2024, 16 (1), pp.2361660. ⟨10.1080/19490976.2024.2361660⟩ Article dans une revue hal-04645842v1
Amyloid-β peptide signature associated with cerebral amyloid angiopathy in familial Alzheimer’s disease with APPdup and Down syndrome Amal Kasri,Elena Camporesi,Eleni Gkanatsiou,Susana Boluda,Gunnar Brinkmalmet al. Acta Neuropathologica, 2024, 148 (1), pp.8. ⟨10.1007/s00401-024-02756-4⟩ Article dans une revue hal-05387918v1
Prenatal Alcohol Exposure Impairs the Placenta–Cortex Transcriptomic Signature, Leading to Dysregulation of Angiogenic Pathways Camille Sautreuil,Maryline Lecointre,Céline Derambure,Carole Brasse-Lagnel,Philippe Lerouxet al. International Journal of Molecular Sciences, 2023, 24 (17), pp.13484. ⟨10.3390/ijms241713484⟩ Article dans une revue hal-05251923v1
Whole Exome/Genome Sequencing Joint Analysis of a Family with Oligogenic Familial Hypercholesterolemia Youmna Ghaleb,Sandy Elbitar,Anne Philippi,Petra El Khoury,Yara Azaret al. Metabolites, 2022, 12 (3), pp.262. ⟨10.3390/metabo12030262⟩ Article dans une revue hal-03642664v1
ABCB6 Polymorphisms are not Overly Represented in Patients with Porphyria Colin P Farrell,Gaël Nicolas,Robert Desnick,Charles J Parker,Jerome Lamorilet al. Blood Advances, 2022, 6 (3), pp.760-766. ⟨10.1182/bloodadvances.2021005484⟩ Article dans une revue hal-03483658v2
Inherited glycosylphosphatidylinositol defects cause the rare Emm-negative blood phenotype and developmental disorders Romain Duval,Gaël Nicolas,Alexandra Willemetz,Yoshiko Murakami,Mahmoud Mikdaret al. Blood, 2021, ⟨10.1182/blood.2020009810⟩ Article dans une revue hal-04974113v1
Phlebotomy as an efficient long-term treatment of congenital erythropoietic porphyria Arienne Mirmiran,Antoine Poli,Cecile Ged,Caroline Schmitt,Thibaud Lefebvreet al. Haematologica, In press, pp.haematol.2019.228270. ⟨10.3324/haematol.2019.228270⟩ Article dans une revue inserm-02441267v1
αII‐spectrin controls calcium‐regulated exocytosis in neuroendocrine chromaffin cells through N-WASP interaction Sébastien Houy,Gaël Nicolas,Fanny Momboisse,Magali Malacombe,Marie-France Baderet al. IUBMB Life, 2020, 72 (4), pp.544-552. ⟨10.1002/iub.2217⟩ Article dans une revue hal-02922314v1
Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation Nathan Rainey,Aoula Moustapha,Ana Saric,Gaël Nicolas,Franck Sureauet al. Cell Death Discovery, 2019, 5, ⟨10.1038/s41420-019-0234-y⟩ Article dans une revue hal-03031432v1
Regulation and tissue-specific expression of δ-aminolevulinic acid synthases in non-syndromic sideroblastic anemias and porphyrias Katell Peoc'H,Gaël Nicolas,Caroline Schmitt,Arienne Mirmiran,Raed Daheret al. Molecular Genetics and Metabolism, 2019, ⟨10.1016/j.ymgme.2019.01.015⟩ Article dans une revue hal-02351175v1
Regulation and tissue-specific expression of δ-aminolevulinic acid synthases in non-syndromic sideroblastic anemias and porphyrias Katell Peoc'H,Gaël Nicolas,Caroline Schmitt,Arienne Mirmiran,Raed Daheret al. Molecular Genetics and Metabolism, 2019, ⟨10.1016/j.ymgme.2019.01.015⟩ Article dans une revue inserm-02075450v1
Erythroid-Progenitor-Targeted Gene Therapy Using Bifunctional TFR1 Ligand-Peptides in Human Erythropoietic Protoporphyria Arienne Mirmiran,Caroline Schmitt,Thibaud Lefebvre,Hana Manceau,Raed Daheret al. American Journal of Human Genetics, 2019, 104 (2), pp.341-347. ⟨10.1016/j.ajhg.2018.12.021⟩ Article dans une revue hal-02328937v1
Lack of the multidrug transporter MRP4/ABCC4 defines the PEL-negative blood group and impairs platelet aggregation Slim Azouzi,Mahmoud Mikdar,Patricia Hermand,Emilie-Fleur Gautier,Virginie Salnotet al. Blood, 2019, 135 (6), pp.441-448. ⟨10.1182/blood.2019002320⟩ Article dans une revue hal-02416860v1
From a dominant to an oligogenic model of inheritance with environmental modifiers in acute intermittent porphyria Hugo Lenglet,Caroline Schmitt,Thomas Grange,Hana Manceau,Narjesse Karboulet al. Human Molecular Genetics, 2018, 27 (7), pp.1164-1173. ⟨10.1093/hmg/ddy030⟩ Article dans une revue hal-02351445v1
Mutation in human CLPX elevates levels of δ- aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria Yvette Yien,Sarah Ducamp,Lisa van Der Vorm,Julia Kardon,Hana Manceauet al. Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (38), pp.E8045-E8052. ⟨10.1073/pnas.1700632114⟩ Article dans une revue inserm-02075468v1
Inactive matriptase-2 mutants found in IRIDA patients still repress hepcidin in a transfection assay despite having lost their serine protease activity. Flavia Guillem,Caroline Kannengiesser,Claire Oudin,Anne Lenoir,Pavle Mataket al. Human Mutation, 2012, 33 (9), pp.1388-96. ⟨10.1002/humu.22116⟩ Article dans une revue inserm-00748562v1
Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6. Anne Lenoir,Jean-Christophe Deschemin,Léon Kautz,Andrew J. Ramsay,Marie-Paule Rothet al. Blood, 2011, 117 (2), pp.647-50. ⟨10.1182/blood-2010-07-295147⟩ Article dans une revue inserm-00552073v1
L'hepcidine, le chef d'orchestre de l'homéostasie du fer Gaël Nicolas Diabète et Obésité, 2009, 4 (29), pp.94-98 Article dans une revue inserm-00378204v1
A mutant alphaII-spectrin designed to resist calpain and caspase cleavage questions the functional importance of this process in vivo. Fleur Meary,Sylvain Metral,Chrystophe Ferreira,Dominique Eladari,Yves Colinet al. Journal of Biological Chemistry, 2007, 282 (19), pp.14226-14237 Article dans une revue inserm-00284621v1
Tyrosine phosphorylation regulates alpha II spectrin cleavage by calpain. Gaël Nicolas,Catherine M. Fournier,Colette Galand,Laurence Malbert-Colas,Odile Bournieret al. Molecular and Cellular Biology, 2002, 22 (10), pp.3527-3536 Article dans une revue inserm-00284770v1
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Gaël Nicolas,Myriam Bennoun,Isabelle Devaux,Carole Beaumont,Bernard Grandchampet al. Proceedings of the National Academy of Sciences of the United States of America, 2001, 98 (15), pp.8780-5. ⟨10.1073/pnas.151179498⟩ Article dans une revue inserm-00331349v1
Spectrin self-association site: characterization and study of beta-spectrin mutations associated with hereditary elliptocytosis. Gaël Nicolas,Sophie Pedroni,Catherine M. Fournier,Huguette Gautero,Constantin T. Craescuet al. Biochemical Journal, 1998, 332 ( Pt 1), pp.81-9 Article dans une revue inserm-00284779v1

Communication dans un congrès (2)

DEFIDIAG-DS: Reasons for accessing secondary findings and the consequences of reporting them in 2500 French patients Eléonore Viora-Dupont,Nicolas Meunier-Beillard,Marion Bouctot,Marie-Laure Asensio,Anne-Sophie Briffaultet al. 58th Conference of the European-Society-of-Human-Genetics (ESHG), May 2025, Milan, Italy Communication dans un congrès hal-05563669v1
Le microbiote et l’hôte: un duo dont les interactions évoluent en fonction des quantités de fer apportées par l’alimentation Marie-Louise Noordine,Yoannes Seyoum,Aurelia Bruneau,Kaleab Baye,Claire Cherbuyet al. Journées francophones de nutrition, SFN et SFNCM, Dec 2023, Marseille, France Communication dans un congrès hal-04337407v1

Pré-publication, Document de travail (1)

Neuronal downregulation of PLCG2 impairs synaptic function and elicits Alzheimer disease hallmarks Audrey Coulon,Florian Rabiller,Mari Takalo,Avishek Roy,Henna Martiskainenet al. 2026 Pré-publication, Document de travail hal-05544909v1

Thèse (1)

Étude fonctionnelle et structurale de certains domaines des spectrines érythroïdes et non érythroïdes : site de tétramérisation et domaine SH3 Gaël Nicolas Sciences du Vivant [q-bio]. Université Paris-Diderot - Paris VII, 1999. Français. ⟨NNT : ⟩ Thèse tel-00284819v1

HDR (1)

Étude fonctionnelle et structurale des spectrines - Découverte de l'hepcidine, une nouvelle hormone de l'homéostasie du fer Gaël Nicolas Sciences du Vivant [q-bio]. Université Paris-Diderot - Paris VII, 2008 HDR tel-00285035v1