Gael Cristofari

31
Documents

Publications

Publications

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LINE-1, the NORth star of nucleolar organization

Misaki Matsuo , Gael Cristofari

Genes and Development, 2025, ⟨10.1101/gad.352583.124⟩

Article dans une revue inserm-04883851v1
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Hominoid-specific retrotransposons fuel regulatory novelty in early brain development

Larisa Okorokova , Gael Cristofari

Cell Genomics, 2025, 5 (10), pp.101038. ⟨10.1016/j.xgen.2025.101038⟩

Article dans une revue inserm-05310407v1
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DNA methylation protects cancer cells against senescence

Xiaoying Chen , Kosuke Yamaguchi , Brianna Rodgers , Delphine Goehrig , David Vindrieux et al.

Nature Communications, 2025, 16 (1), pp.5901. ⟨10.1038/s41467-025-61157-7⟩

Article dans une revue hal-05376983v1
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DNA methylation protects cancer cells against senescence

Xiaoying Chen , Kosuke Yamaguchi , Brianna Rodgers , Delphine Goehrig , David Vindrieux et al.

Nature Communications, 2025, 16 (1), pp.5901. ⟨10.1038/s41467-025-61157-7⟩

Article dans une revue hal-05008358v1
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Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites

Sophie Lanciano , Claude Philippe , Arpita Sarkar , David Pratella , Cécilia Domrane et al.

Cell Genomics, 2024, 4 (2), pp.100498. ⟨10.1016/j.xgen.2024.100498⟩

Article dans une revue hal-04462176v1
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A novel bioinformatic approach reveals cooperation between Cancer/Testis genes in basal-like breast tumors

Marthe Laisné , Brianna Rodgers , Sarah Benlamara , Julien Wicinski , André Nicolas et al.

Oncogene, 2024, 43 (18), pp.1369-1385. ⟨10.1038/s41388-024-03002-7⟩

Article dans une revue hal-04600329v1
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Cancer Immunotherapy: How to Exploit Transposable Elements?

Sophie Lanciano , Gael Cristofari

Clinical Chemistry, 2023, ⟨10.1093/clinchem/hvad091⟩

Article dans une revue inserm-04180892v1

A genome-wide screen reveals new regulators of the 2-cell-like cell state

Nikhil Gupta , Lounis Yakhou , Julien Richard Albert , Anaelle Azogui , Laure Ferry et al.

Nature Structural and Molecular Biology, 2023, 30 (8), pp.1105-1118. ⟨10.1038/s41594-023-01038-z⟩

Article dans une revue pasteur-04181758v1
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Noninvasive and Multicancer Biomarkers: The Promise of LINE-1 Retrotransposons

Aurelien J Doucet , Gael Cristofari

Cancer Discovery, 2023, 13 (12), pp.2502-2504. ⟨10.1158/2159-8290.CD-23-1063⟩

Article dans une revue inserm-04342008v1
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A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation

Lounis Yakhou , Anaelle Azogui , Nikhil Gupta , Julien Richard Albert , Fumihito Miura et al.

Nucleic Acids Research, 2023, pp.gkad719. ⟨10.1093/nar/gkad719⟩

Article dans une revue pasteur-04197719v1
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TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV

Roy Matkovic , Marina Morel , Sophie Lanciano , Pauline Larrous , Benjamin Martin et al.

Nature Communications, 2022, 13 (1), pp.66. ⟨10.1038/s41467-021-27650-5⟩

Article dans une revue hal-03858480v1
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Flip-flop genomics: Charting inversions in the human population

Sophie Lanciano , Gael Cristofari

Cell, 2022, 185 (11), pp.1811-1813. ⟨10.1016/j.cell.2022.05.002⟩

Article dans une revue inserm-03682062v1
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Locus-specific chromatin profiling of evolutionarily young transposable elements

Darren Taylor , Robert Lowe , Claude Philippe , Kevin Cheng , Olivia Grant et al.

Nucleic Acids Research, 2021, 50 (6), pp.e33. ⟨10.1093/nar/gkab1232⟩

Article dans une revue hal-03508519v1
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Nascent RNA m6A modification at the heart of the gene-retrotransposon conflict

Victor Billon , Gael Cristofari

Cell Research, 2021, Online ahead of print. ⟨10.1038/s41422-021-00518-5⟩

Article dans une revue inserm-03259604v1
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The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition

Pablo Tristán-Ramos , Alejandro Rubio-Roldan , Guillermo Peris , Laura Sánchez , Suyapa Amador-Cubero et al.

Nature Communications, 2020, 11 (1), pp.5712. ⟨10.1038/s41467-020-19430-4⟩

Article dans une revue inserm-03261333v1
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Measuring and interpreting transposable element expression

Sophie Lanciano , Gael Cristofari

Nature Reviews Genetics, 2020, 21 (12), pp.721-736. ⟨10.1038/s41576-020-0251-y⟩

Article dans une revue inserm-03261002v1
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The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again

Paul Hofman , Nicholas Ayache , Pascal Barbry , Michel Barlaud , Audrey Bel et al.

Cancers, 2019, 11 (2), pp.1-11. ⟨10.3390/cancers11020250⟩

Article dans une revue hal-02045442v1

FSHD1 and FSHD2 form a disease continuum

Sabrina Sacconi , Audrey Briand-Suleau , Marilyn Gros , Christian Baudoin , Richard J.L.F. Lemmers et al.

Neurology, 2019, 92 (19), pp.e2273-e2285. ⟨10.1212/WNL.0000000000007456⟩

Article dans une revue hal-02305410v1
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The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre-insertion Sequence Biases and Post-insertion Selection

Tania Sultana , Dominic van Essen , Oliver Siol , Marc Bailly-Bechet , Claude Philippe et al.

Molecular Cell, 2019, 74 (3), pp.555-570.e7. ⟨10.1016/j.molcel.2019.02.036⟩

Article dans une revue hal-02401618v1

Inflammatory facioscapulohumeral muscular dystrophy type 2 in 18p deletion syndrome

Dimitri Renard , Guillaume Taieb , Matteo Garibaldi , André Maues de Paula , Rafaelle Bernard et al.

American Journal of Medical Genetics Part A, 2018, 176 (8), pp.1760-1763. ⟨10.1002/ajmg.a.38843⟩

Article dans une revue hal-01991350v1
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Virus-derived DNA drives mosquito vector tolerance to arboviral infection

Bertsy A Goic , Kenneth A Stapleford , Lionel A Frangeul , Aurélien J Doucet , Valérie A Gausson et al.

Nature Communications, 2016, 7, pp.article number 12410. ⟨10.1038/ncomms12410⟩

Article dans une revue pasteur-01377742v1
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International Congress on Transposable elements (ICTE 2016) in Saint Malo: mobile elements under the sun of Brittany

Pascale Lesage , Mireille Bétermier , Antoine Bridier-Nahmias , Michael Chandler , Séverine Chambeyron et al.

Mobile DNA, 2016, 7 (1), pp.19. ⟨10.1186/s13100-016-0075-7⟩

Article dans une revue inserm-01384467v1
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RNA-mediated interference and reverse transcription control the persistence of RNA viruses in the insect model Drosophila

Bertsy Goic , Nicolas Vodovar , Juan A Mondotte , Clément Monot , Lionel Frangeul et al.

Nature Immunology, 2013, 14 (4), pp.396-403. ⟨10.1038/ni.2542⟩

Article dans une revue pasteur-01957212v1
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International Congress on Transposable Elements (ICTE) 2012 in Saint Malo and the sea of TE stories.

Abdelkader Aïnouche , Mireille Bétermier , Mick Chandler , Richard Cordaux , Gaël Cristofari et al.

Mobile DNA, 2012, 3 (1), pp.17. ⟨10.1186/1759-8753-3-17⟩

Article dans une revue inserm-00764323v1

The GAG-like protein of the yeast Ty1 retrotransposon contains a nucleic acid chaperone domain analogous to retroviral nucleocapsid proteins.

G. Cristofari , D. Ficheux , Jl Darlix

Journal of Biological Chemistry, 2000, 275, pp.19210-19217

Article dans une revue hal-00314259v1

Characterization of active reverse transcriptase and nucleoprotein complexes of the yeast retrotransposon Ty3 in vitro.

G. Cristofari , C. Gabus , D. Ficheux , M. Bona , Sf Legrice et al.

Journal of Biological Chemistry, 1999, 274, pp.36643-36648

Article dans une revue hal-00314260v1

Precise and Scarless Insertion of Transposable Elements by Cas9-Mediated Genome Engineering

Vivien Marie Weber , Aurélien J. Doucet , Gael Cristofari

Miguel R. Branco; Alexandre de Mendoza Soler. Transposable Elements, 2607, Springer US, pp.329-353, 2023, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2883-6_15⟩

Chapitre d'ouvrage hal-04246145v1

Genome-Wide Young L1 Methylation Profiling by bs-ATLAS-seq

Claude Philippe , Gael Cristofari

Miguel R. Branco; Alexandre de Mendoza Soler. Transposable Elements, 2607, Springer US, pp.127-150, 2023, Methods in Molecular Biology, 978-1-0716-2882-9. ⟨10.1007/978-1-0716-2883-6_8⟩

Chapitre d'ouvrage hal-04492702v1

Targeted Nanopore Resequencing and Methylation Analysis of LINE-1 Retrotransposons

Arpita Sarkar , Sophie Lanciano , Gael Cristofari

Miguel R. Branco; Alexandre de Mendoza Soler. Transposable Elements, 2607, Springer US, pp.173-198, 2023, Methods in Molecular Biology, 978-1-0716-2882-9. ⟨10.1007/978-1-0716-2883-6_10⟩

Chapitre d'ouvrage inserm-04492760v1

Biochemical Approaches to Study LINE-1 Reverse Transcriptase Activity In Vitro

Sébastien Viollet , Aurélien J Doucet , Gael Cristofari

Transposons and Retrotransposons, pp.357-376, 2016, ⟨10.1007/978-1-4939-3372-3_22⟩

Chapitre d'ouvrage hal-03172454v1