Gérard LIZARD Chercheur Associé au laboratoire Interdisciplinaire Carnot de Bourgogne (ICB), Université Bourgogne Europe (Dijon, France)

Identifiants chercheurs

IdHAL :

gerard-lizard

ORCID :

0000-0001-6330-0172

IdRef :

059247002

Présentation

My primary expertise concerns lipotoxicity of oxysterols as well as lipid metabolism (peroxisome, mitochondria) in the field of aging and age-related diseases (ARD). I have an excellent expertise on oxidative stress, inflammation, and cell death and on the identification of natural and synthetic molecules (polyphenols, phytosterols, aza-stilbenes, fatty acids) and oils in the context of therapeutic strategies focused on ARD. I have a clinical expertise on ARD for the identification of biomarkers, and an important expertise in nanotoxicology. Technically, I am an expert in flow cytometry and image analysis.

Publications

Article dans une revue (115)

7-ketocholesterol as a theranostic target: Potential applications and future perspectives Gérard Lizard,Khouloud Sassi,John J Mackrill,Imen Ghzaiel,Smail Mezianeet al. Chemistry and Physics of Lipids, 2026, 276-277, pp.105588. ⟨10.1016/j.chemphyslip.2026.105588⟩ Article dans une revue (article de synthèse) hal-05590394v1
Preparation of hybrid SPIONs and nanodiamonds in view of neurodegenerative diseases treatments Nimisha Singh,Thomas Nury,Leya Liu,Julien Boudon,Lionel Mauriziet al. Colloids and Surfaces B: Biointerfaces, 2026, 257, pp.115170. ⟨10.1016/j.colsurfb.2025.115170⟩ Article dans une revue hal-05296064v1
Oxysterols, age-related-diseases and nutritherapy: Focus on 7-ketocholesterol and 7β-hydroxycholesterol Anne Vejux,Imen Ghzaiel,John J. Mackrill,Irundika H. K. Dias,Leila Reziget al. Prostaglandins and Other Lipid Mediators, 2025, 178, pp.106993. ⟨10.1016/j.prostaglandins.2025.106993⟩ Article dans une revue hal-05097486v1
Synthesis and structural characterization of coumarin–hydrazone derivatives as antiplatelet agents: in vitro and in silico evaluation of activity and toxicity Asma Haffouz,Emna Khdhiri,Ines Dhouib,Ikram Ben Amor,Amira Jerbiet al. 3 Biotech, 2025, 15 (9), pp.322. ⟨10.1007/s13205-025-04495-z⟩ Article dans une revue hal-05490851v1
Analytical subcellular fractionation of microglial BV-2 cells with peroxisomal beta-oxidation defect Mounia Tahri-Joutey,Isabelle Hamer,Virginie Tevel,Quentin Raas,Catherine Gondcailleet al. Histochemistry and Cell Biology, 2025, 163 (1), pp.44. ⟨10.1007/s00418-025-02372-7⟩ Article dans une revue hal-05097597v1
Influence of Mediterranean Diet and Incidence of Global Warming on Food Habits and Plant Growth in Northern Mediterranean Latitudes: Narrative Review Norbert Latruffe,Gérard Lizard Nutrients, 2025, 17 (4), pp.677. ⟨10.3390/nu17040677⟩ Article dans une revue (article de synthèse) hal-04994065v1
Arginase Activity Inhibition With Thymoquinone Induces a Hybrid Type of Cell‐Death in MDA‐MB‐231 Cell Line Jaweher Bday,Moufida Souid,Vivien Pires,Sallouha Gabbouj,Anne Véjuxet al. Journal of Biochemical and Molecular Toxicology, 2025, 39 (2), pp.e70130. ⟨10.1002/jbt.70130⟩ Article dans une revue hal-04971106v1
Oxysterol-Induced Inflammation in Human Diseases: Strategies for Treatment with Natural Compounds and Synthetic Molecules Fatiha Brahmi,John J. Mackrill,Imen Ghzaiel,Leila Rezig,Rym Benkhalifaet al. Molecules, 2025, 30 (13), pp.2883. ⟨10.3390/molecules30132883⟩ Article dans une revue (article de synthèse) hal-05187131v1
Anthocyanins - dietary natural products with a variety of bioactivities for the promotion of human and animal health Andy Wai Kan Yeung,Magdalena Solka,Artur Jóźwik,Natalia Ksepka,Maima Matinet al. Animal Science Papers and Reports, 2024, 42 (1), pp.5 - 34. ⟨10.2478/aspr-2023-0020⟩ Article dans une revue hal-04666248v1
Current advances in phytosterol free forms and esters: Classification, biosynthesis, chemistry, and detection Farid Khallouki,Wafa Zennouhi,Lhoussain Hajji,Mohamed Bourhia,Laila Benbaceret al. Steroids, 2024, 212, pp.109520. ⟨10.1016/j.steroids.2024.109520⟩ Article dans une revue inserm-04772028v2
Exploring the Role of Apigenin in Neuroinflammation: Insights and Implications Karine Charrière,Vincent Schneider,Manon Perrignon-Sommet,Gérard Lizard,Alexandre Benaniet al. International Journal of Molecular Sciences, 2024, 25 (9), pp.5041. ⟨10.3390/ijms25095041⟩ Article dans une revue (article de synthèse) hal-04666378v1
Lipid droplets dependent or independent cytoprotective activities of unsaturated fatty acids, Lorenzo’s oil and sulfo-N-succinimidyl oleate on 7-ketocholesterol-induced oxidative stress, organelle dysfunction and cell death on 158N and ARPE-19 cells: Cell targets and benefits of sulfo-N-succinimidyl oleate Thomas Nury,Imen Ghzaiel,Aziz Hichami,Claudio Caccia,Valerio Leoniet al. Current Research in Biotechnology, 2024, 7, pp.100195. ⟨10.1016/j.crbiot.2024.100195⟩ Article dans une revue hal-04664953v2
Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol – Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue Aline Yammine,Imen Ghzaiel,Vivien Pires,Amira Zarrouk,Omar Kharoubiet al. Current Research in Toxicology, 2024, 6, pp.100153. ⟨10.1016/j.crtox.2024.100153⟩ Article dans une revue hal-04665371v1
Octadecaneuropeptide, ODN, Promotes Cell Survival against 6-OHDA-Induced Oxidative Stress and Apoptosis by Modulating the Expression of miR-34b, miR-29a, and miR-21in Cultured Astrocytes Amine Bourzam,Yosra Hamdi,Seyma Bahdoudi,Karthi Duraisamy,Mouna El Mehdiet al. Cells, 2024, 13 (14), pp.1188. ⟨10.3390/cells13141188⟩ Article dans une revue hal-04669034v1
Characterization of &lt;i&gt;Silybum marianum&lt;/i&gt; and &lt;i&gt;Silybum eburneum&lt;/i&gt; seed oils: Phytochemical profiles and antioxidant properties supporting important nutritional interests Samah Maaloul,Imen Ghzaiel,Maher Mahmoudi,Hédi Mighri,Vivien Pireset al. PLoS ONE, 2024, 19 (6), pp.e0304021. ⟨10.1371/journal.pone.0304021⟩ Article dans une revue hal-04666055v1
European Network for oxysterol research (ENOR): 10th ENOR symposium – Web meeting Gérard Lizard,Marc Poirot,Luigi Iuliano Steroids, 2023, 195, pp.109242. ⟨10.1016/j.steroids.2023.109242⟩ Article dans une revue inserm-04165320v1
Two Argan Oil Phytosterols, Schottenol and Spinasterol, Attenuate Oxidative Stress and Restore LPS-Dysregulated Peroxisomal Functions in &lt;i&gt;Acox1&lt;sup&gt;−/−&lt;/sup&gt;&lt;/i&gt; and Wild-Type BV-2 Microglial Cells Soukaina Essadek,Catherine Gondcaille,Stéphane Savary,Mohammad Samadi,Joseph Vamecqet al. Antioxidants , 2023, 12 (1), pp.168. ⟨10.3390/antiox12010168⟩ Article dans une revue hal-03994321v1
Celebrating the 10th anniversary of the creation of the European Network for Oxysterol Research (ENOR) Gérard Lizard,Marc Poirot,Luigi Iuliano Journal of Steroid Biochemistry and Molecular Biology, 2022, pp.106114. ⟨10.1016/j.jsbmb.2022.106114⟩ Article dans une revue inserm-03649224v1
The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis Rajeev K. Singla,Ronita De,Thomas Efferth,Bruno Mezzetti,M. D. Sahab Uddinet al. Phytomedicine, 2022, 108, pp.154520. ⟨10.1016/j.phymed.2022.154520⟩ Article dans une revue hal-03994795v1
Profiles of Fatty Acids, Polyphenols, Sterols, and Tocopherols and Scavenging Property of Mediterranean Oils: New Sources of Dietary Nutrients for the Prevention of Age-related Diseases Leila Rezig,Lucy Martine,Thomas Nury,Kamel Msaada,Nesrine Mahfoudhiet al. Journal of oleo science, 2022, 71 (8), pp.1117-1133. ⟨10.5650/jos.ess22110⟩ Article dans une revue hal-03749395v1
Cytoprotective activities of representative nutrients from the Mediterranean diet and of Mediterranean oils against 7-ketocholesterol- and 7β-hydroxycholesterol-induced cytotoxicity: Application to age-related diseases and civilization diseases Leila Rezig,Imen Ghzaiel,Mohamed Ksila,Aline Yammine,Thomas Nuryet al. Steroids, 2022, 187, pp.109093. ⟨10.1016/j.steroids.2022.109093⟩ Article dans une revue hal-04842281v1
Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: Nutritional insights associated with the concept of pexotherapy Imen Ghzaiel,Amira Zarrouk,Soukaina Essadek,Lucy Martine,Souha Hammoudaet al. Steroids, 2022, 183, pp.109032. ⟨10.1016/j.steroids.2022.109032⟩ Article dans une revue hal-03715700v1
Sources of 7-ketocholesterol, metabolism and inactivation strategies: food and biomedical applications Imen Ghzaiel,Khouloud Sassi,Amira Zarrouk,Shubhrima Ghosh,Irundika Diaset al. Redox Experimental Medicine, 2022, 2022 (1), pp.R40-R56. ⟨10.1530/REM-22-0005⟩ Article dans une revue hal-04506089v1
Protective Effect of Nopal Cactus (Opuntia ficus-indica) Seed Oil against Short-Term Lipopolysaccharides-Induced Inflammation and Peroxisomal Functions Dysregulation in Mouse Brain and Liver Mounia Tahri-Joutey,Fatima-Ezzahra Saih,Riad El Kebbaj,Catherine Gondcaille,Joseph Vamecqet al. International Journal of Molecular Sciences, 2022, 23 (19), pp.11849. ⟨10.3390/ijms231911849⟩ Article dans une revue hal-04342093v1
European network for oxysterol research (ENOR): 10 th anniversary Gérard Lizard,Marc Poirot,Luigi Iuliano Journal of Steroid Biochemistry and Molecular Biology, 2021, 214, pp.105996. ⟨10.1016/j.jsbmb.2021.105996⟩ Article dans une revue inserm-03394448v1
Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age-related diseases T. Nury,A. Yammine,I. Ghzaiel,K. Sassi,A. Zarrouket al. Ageing Research Reviews - ARR, 2021, 68, pp.101324. ⟨10.1016/j.arr.2021.101324⟩ Article dans une revue hal-04506059v1
Antioxidant properties and cytoprotective effect of pistacia lentiscus l. Seed oil against 7β-hydroxycholesterol-induced toxicity in c2c12 myoblasts: Reduction in oxidative stress, mitochondrial and peroxisomal dysfunctions and attenuation of cell death Imen Ghzaiel,Amira Zarrouk,Thomas Nury,Michela Libergoli,Francesca Florioet al. Antioxidants , 2021, 10 (11), pp.1772. ⟨10.3390/antiox10111772⟩ Article dans une revue hal-03443580v1
7-Ketocholesterol: Effects on viral infections and hypothetical contribution in COVID-19 Imen Ghzaiel,Khouloud Sassi,Amira Zarrouk,Thomas Nury,Mohamed Ksilaet al. Journal of Steroid Biochemistry and Molecular Biology, 2021, 212, pp.105939. ⟨10.1016/j.jsbmb.2021.105939⟩ Article dans une revue hal-04842319v1
7-ketocholesterol and 7β-hydroxycholesterol: in vitro and animal models used to characterize their activities and to identify molecules preventing their toxicity Anne Vejux,Dehbia Abed-Vieillard,Khadija Hajji,Amira Zarrouk,John Mackrillet al. Biochemical Pharmacology, 2020, 173, pp.113648. ⟨10.1016/j.bcp.2019.113648⟩ Article dans une revue (article de synthèse) hal-02308654v1
Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in Vitro and in Vivo Models of Neurodegenerative Diseases Olfa Masmoudi-Kouki,Amira Namsi,Yosra Hamdi,Seyma Bahdoudi,Ikram Ghouiliet al. Frontiers in Endocrinology, 2020, 11, pp.566026. ⟨10.3389/fendo.2020.566026⟩ Article dans une revue (article de synthèse) hal-05156163v1
7-Ketocholesterol- and 7β-Hydroxycholesterol-Induced Peroxisomal Disorders in Glial, Microglial and Neuronal Cells: Potential Role in Neurodegeneration Thomas Nury,Aline Yammine,Franck Menetrier,Amira Zarrouk,Anne Vejuxet al. Advances in Experimental Medicine and Biology, 2020, Advances in Experimental Medicine and Biology, 1299, pp.31-41. ⟨10.1007/978-3-030-60204-8_3⟩ Article dans une revue hal-04759823v1
Taurine-Conjugated Mussel-Inspired Iron Oxide Nanoparticles with an Elongated Shape for Effective Delivery of Doxorubicin into the Tumor Cells Nimisha Singh,Nadine Millot,Lionel Maurizi,Gérard Lizard,Rajender Kumar ACS Omega, 2020, 5 (26), pp.16165-16175. ⟨10.1021/acsomega.0c01747⟩ Article dans une revue hal-02902885v1
Oxysterols and sterols: from lipidomics to food sciences M Rodriguez-Estrada,V Cardenia,Marc Poirot,L Iuliano,G. Lizard Journal of Steroid Biochemistry and Molecular Biology, 2019, 196, pp.105515. ⟨10.1016/j.jsbmb.2019.105515⟩ Article dans une revue inserm-02380514v1
Elaboration of Trans-Resveratrol Derivative-Loaded Superparamagnetic Iron Oxide Nanoparticles for Glioma Treatment Fadoua Sallem,Rihab Haji,Dominique Vervandier-Fasseur,Thomas Nury,Lionel Mauriziet al. Nanomaterials, 2019, 9 (2), pp.287. ⟨10.3390/nano9020287⟩ Article dans une revue hal-02163534v1
Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol Randa Sghaier,Thomas Nury,Valerio Leoni,Claudio Caccia,Jean-Paul Pais de Barroset al. Journal of Steroid Biochemistry and Molecular Biology, 2019, 194, pp.105432. ⟨10.1016/j.jsbmb.2019.105432⟩ Article dans une revue hal-03487954v1
A microglial cell model for acyl-CoA oxidase 1 deficiency Q. Raas,F-E Saih,C. Gondcaille,D. Trompier,Y. Hamonet al. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2019, 1864 (4), pp.567-576. ⟨10.1016/j.bbalip.2018.10.005⟩ Article dans une revue hal-02359450v1
Profile of fatty acids, tocopherols, phytosterols and polyphenols in mediterranean oils (argan oils, olive oils, milk thistle seed oils and nigella seed oil) and evaluation of their antioxidant and cytoprotective activities Amira Zarrouk,Lucy Martine,Stéphane Grégoire,Thomas Nury,Wiem Meddebet al. Current Pharmaceutical Design, 2019, 25 (15), pp.1791-1805. ⟨10.2174/1381612825666190705192902⟩ Article dans une revue (article de synthèse) istex hal-02622321v1
Induction of a non-apoptotic mode of cell death associated with autophagic characteristics with steroidal maleic anhydrides and 7β-hydroxycholesterol on glioma cells K. Sassi,T. Nury,A. Zarrouk,R. Sghaier,A. Khalafi-Nezhadet al. Journal of Steroid Biochemistry and Molecular Biology, 2019, 191, pp.105371. ⟨10.1016/j.jsbmb.2019.04.020⟩ Article dans une revue hal-03485843v1
Flavonoids differentially modulate liver X receptors activity—Structure-function relationship analysis Allan Fouache,Nada Zabaiou,Cyrille de Joussineau,Laurent Morel,Sandrine Silvente-Poirotet al. Journal of Steroid Biochemistry and Molecular Biology, 2019, 190, pp.173-182. ⟨10.1016/j.jsbmb.2019.03.028⟩ Article dans une revue inserm-02380571v1
Octadecaneuropeptide (ODN) Induces N2a Cells Differentiation through a PKA/PLC/PKC/MEK/ERK-Dependent Pathway: Incidence on Peroxisome, Mitochondria, and Lipid Profiles Amira Namsi,Thomas Nury,Amira Khan,Jérôme Leprince,David Vaudryet al. Molecules, 2019, 24 (18), pp.3310. ⟨10.3390/molecules24183310⟩ Article dans une revue hal-02292144v1
Peroxisomes in Immune Response and Inflammation Francesca Di Cara,Pierre Andreoletti,Doriane Trompier,Anne Vejux,Margret H Bülowet al. International Journal of Molecular Sciences, 2019, 20 (16), ⟨10.3390/ijms20163877⟩ Article dans une revue (article de synthèse) hal-04346483v1
Protective function of autophagy during VLCFA-induced cytotoxicity in a neurodegenerative cell model Margaux Doria,Thomas Nury,Dominique Delmas,Thibault Moreau,Gérard Lizardet al. Free Radical Biology and Medicine, 2019, 137, pp.46 - 58. ⟨10.1016/j.freeradbiomed.2019.04.016⟩ Article dans une revue hal-03484454v1
CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy Q. Raas,C. Gondcaille,Y. Hamon,V. Leoni,C. Cacciaet al. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2019, 1864 (5), pp.704-714. ⟨10.1016/j.bbalip.2019.02.006⟩ Article dans une revue hal-02359446v1
Correlation of trans fatty acids with the severity of coronary artery disease lesions Samia Hadj Ahmed,Wafa Kharroubi,Nadia Kaoubaa,Amira Zarrouk,Fathi Batboutet al. Lipids in Health and Disease, 2018, 17 (1), ⟨10.1186/s12944-018-0699-3⟩ Article dans une revue hal-01932790v1
Cytoprotective activities of milk thistle seed oil used in traditional tunisian medicine on 7-ketocholesterol and 24s-hydroxycholesterol-induced toxicity on 158n murine oligodendrocytes Wiem Meddeb,Leila Rezig,Amira Zarrouk,Thomas Nury,Anne Vejuxet al. Antioxidants , 2018, 7 (7), pp.95. ⟨10.3390/antiox7070095⟩ Article dans une revue hal-02621118v1
The effect of oxysterols on nerve impulses. Maryem Bezine,Amira Namsi,Randa Sghaier,Rym Ben Khalifa,Haithem Hamdouniet al. Biochimie, 2018, ⟨10.1016/j.biochi.2018.04.013⟩ Article dans une revue istex hal-01873841v1
Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol Thomas Nury,Randa Sghaier,Amira Zarrouk,Franck Menetrier,Tugba Uzunet al. Biochimie, 2018, 153, pp.181-202. ⟨10.1016/j.biochi.2018.07.009⟩ Article dans une revue istex hal-02621805v1
In vitro interaction and biocompatibility of titanate nanotubes with microglial cells S. Sruthi,A. Loiseau,J. Boudon,F. Sallem,Lionel Mauriziet al. Toxicology and Applied Pharmacology, 2018, 353, pp.74-86. ⟨10.1016/j.taap.2018.06.013⟩ Article dans une revue hal-02163529v1
Lipid Biomarkers in Alzheimer's Disease Amira Zarrouk,Meryam Debbabi,Maryem Bezine,El Mostafa Karym,Asmaa Badreddineet al. Current Alzheimer Research, 2018, 15 (4), pp.303-312. ⟨10.2174/1567205014666170505101426⟩ Article dans une revue pasteur-01964927v1
Modulation of Kv3.1b potassium channel level and intracellular potassium concentration in 158N murine oligodendrocytes and BV-2 murine microglial cells treated with 7-ketocholesterol, 24S-hydroxycholesterol or tetracosanoic acid (C24:0) Maryem Bezine,Sonia Maatoug,Rym Ben Khalifa,Meryam Debbabi,Amira Zarrouket al. Biochimie, 2018, 153, pp.56-69. ⟨10.1016/j.biochi.2018.02.008⟩ Article dans une revue hal-01876263v1
Cellular interactions of functionalized superparamagnetic iron oxide nanoparticles on oligodendrocytes without detrimental side effects: Cell death induction, oxidative stress and inflammation S. Sruthi,Lionel Maurizi,T. Nury,F. Sallem,J. Boudonet al. Colloids and Surfaces B: Biointerfaces, 2018, 170, pp.454-462. ⟨10.1016/j.colsurfb.2018.06.041⟩ Article dans une revue hal-02163524v1
Flow Cytometric Analysis of the Expression Pattern of Peroxisomal Proteins, Abcd1, Abcd2, and Abcd3 in BV-2 Murine Microglial Cells. Meryam Debbabi,Thomas Nury,Imen Helali,El Mostafa Karym,Flore Geillonet al. Methods in Molecular Biology, 2017, 1595, pp.257-265. ⟨10.1007/978-1-4939-6937-1_25⟩ Article dans une revue hal-01539021v1
Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells Meryam Debbabi,Amira Zarrouk,Maryem Bezine,Wiem Meddeb,Thomas Nuryet al. Chemistry and Physics of Lipids, 2017, 207 (Pt B), pp.151-170. ⟨10.1016/j.chemphyslip.2017.04.002⟩ Article dans une revue istex hal-01912331v1
Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N Asmaa Badreddine,Amira Zarrouk,El Mostafa Karym,Meryam Debbabi,Thomas Nuryet al. International Journal of Molecular Sciences, 2017, 18 (10), pp.2220. ⟨10.3390/ijms18102220⟩ Article dans une revue hal-01685177v1
Evidence of biological activity of Mentha species extracts on apoptotic and autophagic targets on murine RAW264.7 and human U937 monocytic cells Fatiha Brahmi,Samia Hadj-Ahmed,Amira Zarrouk,Maryem Bezine,Thomas Nuryet al. Pharmaceutical biology, 2017, 55 (1), pp.286-293. ⟨10.1080/13880209.2016.1235208⟩ Article dans une revue hal-01513649v1
Evidence of K+ homeostasis disruption in cellular dysfunction triggered by 7-ketocholesterol, 24S-hydroxycholesterol, and tetracosanoic acid (C24:0) in 158N murine oligodendrocytes Maryem Bezine,Meryam Debbabi,Thomas Nury,Rym Ben-Khalifa,Mohammad Samadiet al. Chemistry and Physics of Lipids, 2017, 207 (Pt B), pp.135-150. ⟨10.1016/j.chemphyslip.2017.03.006⟩ Article dans une revue istex pasteur-01964971v1
Protective Effect of Cactus Cladode Extracts on Peroxisomal Functions in Microglial BV-2 Cells Activated by Different Lipopolysaccharides Fatima-Ezzahra Saih,Pierre Andreoletti,Stéphane Mandard,Norbert Latruffe,M'Hammed Saïd El Kebbajet al. Molecules, 2017, 22 (1), pp.E102. ⟨10.3390/molecules22010102⟩ Article dans une revue inserm-01432713v1
Oxysterols and phytosterols in human health Gérard Lizard,Charbel Massaad,Luigi Iuliano Chemistry and Physics of Lipids, 2017, Epub ahead of print. ⟨10.1016/j.chemphyslip.2017.08.005⟩ Article dans une revue inserm-01590603v1
Mitochondrial dysfunction, oxidative stress and apoptotic induction in microglial BV-2 cells treated with sodium arsenate. Wafa Kharroubi,Samia Haj Ahmed,Thomas Nury,Pierre Andreoletti,Rachid Saklyet al. Journal of Environmental Sciences, 2017, 51, pp.44-51. ⟨10.1016/j.jes.2016.08.028⟩ Article dans une revue istex hal-01463001v1
Attenuation of 7-ketocholesterol-induced overproduction of reactive oxygen species, apoptosis, and autophagy by dimethyl fumarate on 158 N murine oligodendrocytes Amira Zarrouk,Thomas Nury,El-Mostafa Karym,Anne Vejux,Randa Sghaieret al. Journal of Steroid Biochemistry and Molecular Biology, 2017, 169, pp.29-38. ⟨10.1016/j.jsbmb.2016.02.024⟩ Article dans une revue istex hal-04342669v1
Contribution of cholesterol and oxysterols to the pathophysiology of Parkinson's disease. Margaux Doria,Lucie Maugest,Thibault Moreau,Gérard Lizard,Anne Vejux Advances in Free Radical Biology & Medicine, 2016, 101, pp.393-400. ⟨10.1016/j.freeradbiomed.2016.10.008⟩ Article dans une revue istex hal-01455156v1
Generation of oxysterols formed by free radicals and enzymes by electrochemical oxidation Gérard Lizard European Journal of Lipid Science and Technology, 2016, 118 (2), pp.135-136 Article dans une revue hal-01448150v1
STUDY OF THE ANTIOXIDANT ACTIVITY OF THE EXTRACTS OF THE ACHENES OF Sylibum marianum L. Fatima Zohra Bessam,Zoheir Mehdadi,Gérard Lizard,Riad Djellouli The International journal of biochemistry, 2016, 3 (2), pp.63-72 Article dans une revue hal-05381378v1
Evidence of hormesis on human neuronal SK-N-BE cells treated with sodium arsenate: impact at the mitochondrial level. Wafa Kharroubi,Samia Haj Ahmed,Thomas Nury,Pierre Andreoletti,Zohra Haouaset al. Environmental Science and Pollution Research, 2016, 23 (9), pp.8441-52. ⟨10.1007/s11356-016-6043-4⟩ Article dans une revue hal-01463067v1
Microglial cells (BV-2) internalize titanium dioxide (TiO2) nanoparticles: toxicity and cellular responses Naima Rihane,Thomas Nury,Imen M’rad,Lassaad El Mir,Mohsen Saklyet al. Environmental Science and Pollution Research, 2016, 23 (10), pp.9690 - 9699. ⟨10.1007/s11356-016-6190-7⟩ Article dans une revue hal-01389750v1
Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells. Meryam Debbabi,Thomas Nury,Amira Zarrouk,Nadia Mekahli,Maryem Bezineet al. International Journal of Molecular Sciences, 2016, 17 (12), pp.E1973. ⟨10.3390/ijms17121973⟩ Article dans une revue hal-01463786v1
Argan oil prevents down-regulation induced by endotoxin on liver fatty acid oxidation and gluconeogenesis and on peroxisome proliferator-activated receptor gamma coactivator-1 alpha, (PGC-1alpha), peroxisome proliferator-activated receptor gamma (PPARgamma) and estrogen related receptor alpha (ERRalpha) Riad El Kebbaj,Pierre Andreoletti,Hammam L El Hajj,Youssef El Kharrassi,Joseph Vamecqet al. Biochimie Open, 2015, 1, pp.51-59. ⟨10.1016/j.biopen.2015.10.002⟩ Article dans une revue inserm-01534672v1
An expeditious synthesis of spinasterol and schottenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system Asmaa Badreddine,Karym El Mostafa,Amira Zarrouk,Thomas Nury,Youssef El Kharrassiet al. Steroids, 2015, 99 (B, SI), pp.119-124. ⟨10.1016/j.steroids.2015.01.005⟩ Article dans une revue istex hal-01518108v1
Effects of cholesterol oxides on cell death induction and calcium increase in human neuronal cells (SK-N-BE) and evaluation of the protective effects of docosahexaenoic acid (DHA; C22:6 n-3) Amira Zarrouk,Thomas Nury,Mohammad Samadi,Yvonne O'Callaghan,Mohamed Hammamiet al. Steroids, 2015, 99 (B, SI), pp.238-247. ⟨10.1016/j.steroids.2015.01.018⟩ Article dans une revue istex hal-01518107v1
Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7 beta-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of alpha-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3) Thomas Nury,Amira Zarrouk,John J. Mackrill,Mohammad Samadi,Philippe Durandet al. Steroids, 2015, 99 (B, SI), pp.194-203. ⟨10.1016/j.steroids.2015.02.003⟩ Article dans une revue istex hal-01518110v1
LXR antagonists induce ABCD2 expression Catherine Gondcaille,Emmanuelle C. Genin,Tatiana E. Lopez,Alexandre M.M. Dias,Flore Geillonet al. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2014, 1841 (2), pp.259-266. ⟨10.1016/j.bbalip.2013.11.003⟩ Article dans une revue hal-01185659v1
The role of reactive oxygen species and subsequent DNA-damage response in the emergence of resistance towards resveratrol in colon cancer models D J Colin,E Limagne,K Ragot,G Lizard,F Ghiringhelliet al. Cell Death & Disease, 2014, 5 (11), ⟨10.1038/cddis.2014.486⟩ Article dans une revue hal-04866542v1
Biological activities of Schottenol and Spinasterol, two natural phytosterols present in argan oil and in cactus pear seed oil, on murine miroglial BV2 cells M'Hammed Saïd El Kebbaj,David Masson,Gérard Lizard,Boubker Nasser,Mustapha Cherkaoui-Malkiet al. Biochemical and Biophysical Research Communications, 2014, 446 (3, SI), pp.798-804. ⟨10.1016/j.bbrc.2014.02.074⟩ Article dans une revue istex hal-01518331v1
Brain Peroxisomes Doriane Trompier,A. Vejux,A. Zarrouk,Catherine Gondcaille,Flore Geillonet al. Biochimie, 2013, 98, pp.102-110. ⟨10.1016/j.biochi.2013.09.009⟩ Article dans une revue hal-01185043v1
Improved synthesis and in vitro evaluation of the cytotoxic profile of oxysterols oxidized at C4 (4 alpha- and 4 beta-hydroxycholesterol) and C7 (7-ketocholesterol, 7 alpha- and 7 beta-hydroxycholesterol) on cells of the central nervous system Thomas Nury,Mohammad Samadi,Amira Zarrouk,Jean Marc Riedinger,Gérard Lizard European Journal of Medicinal Chemistry, 2013, 70, pp.558-567. ⟨10.1016/j.ejmech.2013.09.028⟩ Article dans une revue istex hal-01518904v1
Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors. Nicolas Isambert,Pierre Fumoleau,Catherine Paul,Christophe Ferrand,Sylvie Zanettaet al. BMC Cancer, 2013, 13 (1), pp.172. ⟨10.1186/1471-2407-13-172⟩ Article dans une revue inserm-00813522v1
Peroxisomal ABC transporters and X-linked adrenoleukodystrophy Flore Geillon,Doriane Trompier,Catherine Gondcaille,Gérard Lizard,Stéphane Savary Médecine/Sciences, 2012, 28 (12), pp.1087-1094. ⟨10.1051/medsci/20122812019⟩ Article dans une revue hal-01221377v1
Correlational selection on pro- and anti-inflammatory effectors. Romain Guerreiro,Anne A. Besson,Jérôme Bellenger,Kévin Ragot,Gérard Lizardet al. Evolution - International Journal of Organic Evolution, 2012, 66 (11), pp.3615-3623. ⟨10.1111/j.1558-5646.2012.01708.x⟩ Article dans une revue hal-00762702v1
Incidence of Abcd1 level on the induction of cell death and organelle dysfunctions triggered by very long chain fatty acids and TNF-alpha on oligodendrocytes and astrocytes Mauhamad Baarine,Kevin Ragot,Anne Athias,Thomas Nury,Zilal Kattanet al. NeuroToxicology, 2012, 33 (2), pp.212-228. ⟨10.1016/j.neuro.2011.10.007⟩ Article dans une revue istex hal-02651080v1
The inflammatory response in acyl-CoA oxidase 1 deficiency (pseudoneonatal adrenoleukodystrophy). Hammam I. El Hajj,Aurore Vluggens,Pierre Andreoletti,Kevin Ragot,Stéphane Mandardet al. Endocrinology, 2012, 153 (6), pp.2568-75. ⟨10.1210/en.2012-1137⟩ Article dans une revue inserm-00692894v1
Absence of oxysterol-like side effects in human monocytic cells treated with phytosterols and oxyphytosterols Anne Vejux,Thomas Montange,Lucy Martine,Amira Zarrouk,Jean-Marc Riedingeret al. Journal of Agricultural and Food Chemistry, 2012, 60 (16), pp.4060-4066. ⟨10.1021/jf300487r⟩ Article dans une revue hal-01594323v1
Impact of 7-Ketocholesterol and Very Long Chain Fatty Acids on Oligodendrocyte Lipid Membrane Organization: Evaluation Via LAURDAN and FAMIS Spectral Image Analysis Edmond Kahn,Mauhamad Baarine,Aurélien Dauphin,Kevin Ragot,Nicolas Tissotet al. Cytometry Part A, 2011, 79A (4), pp.293 - 305. ⟨10.1002/cyto.a.21017⟩ Article dans une revue hal-02652769v1
Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol. B. Dugas,Soeli Charbonnier,Mauhamad Baarine,Kevin Ragot,Dominique Delmaset al. European Journal of Nutrition, 2010, 49 (7), pp.435-46. ⟨10.1007/s00394-010-0102-2⟩ Article dans une revue hal-00514897v1
Effects of resveratrol analogs on cell cycle progression, cell cycle associated proteins and 5fluoro-uracil sensitivity in human derived colon cancer cells. Didier Colin,Amandine Gimazane,Gérard Lizard,Jean-Claude Izard,Eric Solaryet al. International Journal of Cancer, 2009, 124 (12), pp.2780-8. ⟨10.1002/ijc.24264⟩ Article dans une revue hal-00374912v1
Branched-chain fatty acids, increased in tears of blepharitis patients, are not toxic for conjunctival cells Corinne Joffre,Maxime Souchier,Laurent Leclere,Bénédicte Buteau,Stéphane Grégoireet al. British Journal of Ophthalmology, 2009, 93 (10), pp.1391-n/a. ⟨10.1136/bjo.2008.156356⟩ Article dans une revue hal-00477844v1
Preanalytical guidelines for clinical proteomics investigation of biological fluids Sylvain Lehmann,S. Roche,Y. Allory,A. Barthelaix,J.-L. Beaudeuxet al. Annales de Biologie Clinique, 2009, 67 (6), pp.629-639. ⟨10.1684/abc.2009.0374⟩ Article dans une revue hal-00444355v1
Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis Anne Vejux,Stéphane Guyot,Thomas Montange,Jean-Marc Riedinger,Edmond Kahnet al. The Journal of Nutritional Biochemistry, 2009, 20 (1), pp.45-61. ⟨10.1016/j.jnutbio.2007.12.001⟩ Article dans une revue istex hal-02291044v1
Peroxisomal and mitochondrial status of two murine oligodendrocytic cell lines (158N, 158JP): potential models for the study of peroxisomal disorders associated with dysmyelination processes. Mauhamad Baarine,Kevin Ragot,Emmanuelle C. Genin,Hammam El Hajj,Doriane Trompieret al. Journal of Neurochemistry, 2009, 111 (1), pp.119-31. ⟨10.1111/j.1471-4159.2009.06311.x⟩ Article dans une revue hal-00514890v1
7β-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells. Oxysterols-induced IL-8 secretion is calcium-dependent Stéphanie Lemaire-Ewing,Arnaud Berthier,Marie Charlotte Royer,Emmanuelle Logette,Laurent Corcoset al. Cell Biology and Toxicology, 2008, 25, pp.127 - 139. ⟨10.1007/s10565-008-9063-0⟩ Article dans une revue hal-04200422v1
Inhibitory effects of trans-resveratrol analogs molecules on the proliferation and the cell cycle progression of human colon tumoral cells. Anna-Kristina Marel,Gérard Lizard,Jean-Claude Izard,Norbert Latruffe,Dominique Delmas Molecular Nutrition and Food Research, 2008, 52 (5), pp.538-48. ⟨10.1002/mnfr.200700185⟩ Article dans une revue istex hal-00281570v1
Antiproliferative activities of resveratrol and related compounds in human hepatocyte derived HepG2 cells are associated with biochemical cell disturbance revealed by fluorescence analyses. Didier Colin,Allan Lancon,Dominique Delmas,Gérard Lizard,Jessica Abrossinowet al. Biochimie, 2008, 90 (11-12), pp.1674-84. ⟨10.1016/j.biochi.2008.06.006⟩ Article dans une revue hal-00376084v1
Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol Laure Malvitte,Thomas Montange,Anne Vejux,Corinne Joffre,Alain M. Bronet al. Current Eye Research, 2008, 33 (9), pp.769-781. ⟨10.1080/02713680802337397⟩ Article dans une revue hal-02664689v1
Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs Laure Malvitte,Thomas Montange,Anne Vejux,Christophe Baudouin,Alain M. Bronet al. British Journal of Ophthalmology, 2007, 91 (1), pp.29-32. ⟨10.1136/bjo.2006.101485⟩ Article dans une revue hal-02663332v1
Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation. Anne Vejux,Edmond Kahn,Franck Ménétrier,Thomas Montange,Jeannine Lherminieret al. Histochemie / Histochemistry Histochimie, 2007, 127 (6), pp.609-24. ⟨10.1007/s00418-006-0268-0⟩ Article dans une revue istex inserm-00164342v1
Resveratrol in human hepatoma HepG2 cells: metabolism and inducibility of detoxifying enzymes. Allan Lançon,Nathalie Hanet,Brigitte Jannin,Dominique Delmas,Jean-Marie Heydelet al. Drug Metabolism and Disposition, 2007, 35 (5), pp.699-703. ⟨10.1124/dmd.106.013664⟩ Article dans une revue hal-00259260v1
Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells Corinne Joffre,Laurent Leclere,Bénédicte Buteau,Lucy Martine,Stéphanie S. Cabaretet al. Current Eye Research, 2007, 32 (3), pp.271-280. ⟨10.1080/02713680601187951⟩ Article dans une revue hal-02659823v1
Effects of caspase inhibitors (z-VAD-fmk, z-VDVAD-fmk) on Nile Red fluorescence pattern in 7-ketocholesterol-treated cells: Investigation by flow cytometry and spectral imaging microscopy. Anne Vejux,Gérard Lizard,Yves Tourneur,Jean-Marc Riedinger,Frédérique Frouinet al. Cytometry Part A, 2007, 71A (8), pp.550-562. ⟨10.1002/cyto.a.20410⟩ Article dans une revue inserm-00164348v1
Analogies entre le processus athéromateux et dégénérescence maculaire liée à l'âge : roles présumés des oxystérols Laure Malvitte,Thomas Montange,Corinne Joffre,Aline Vejux,Caroline Maïzaet al. Journal Français d'Ophtalmologie, 2006, 29 (5), pp.570-578. ⟨10.1016/S0181-5512(06)73815-3⟩ Article dans une revue hal-02662961v1
Flow cytometry and spectral imaging multiphoton microscopy analysis of CD36 expression with quantum dots 605 of untreated and 7-ketocholesterol-treated human monocytic cells. Edmond Kahn,Franck Ménétrier,Anne Vejux,Thomas Montange,Dominique Dumaset al. Analytical and Quantitative Cytology and Histology, 2006, 28 (6), pp.316-30 Article dans une revue hal-00559053v1
7-Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry, FRET biphoton spectral imaging microscopy, and subcellular fractionation. Anne Vejux,Edmond Kahn,Dominique Dumas,Ginette Bessède,Franck Ménétrieret al. Cytometry Part A, 2005, 64 (2), pp.87-100. ⟨10.1002/cyto.a.20124⟩ Article dans une revue hal-00559063v1
Activation of caspase-3-dependent and -independent pathways during 7-ketocholesterol- and 7beta-hydroxycholesterol-induced cell death: a morphological and biochemical study. Prunet Céline,Lemaire-Ewing Stéphanie,Ménétrier Franck,Néel Dominique,Gérard Lizard Journal of Biochemical and Molecular Toxicology, 2005, 19 (5), pp.311-26. ⟨10.1002/jbt.20096⟩ Article dans une revue istex hal-04971160v1
FRET multiphoton spectral imaging microscopy of 7-ketocholesterol and Nile Red in U937 monocytic cells loaded with 7-ketocholesterol. Edmond Kahn,Anne Vejux,Dominique Dumas,Thomas Montange,Frédérique Frouinet al. Analytical and Quantitative Cytology and Histology, 2004, 26 (6), pp.304-13 Article dans une revue hal-00559065v1
Analysis of fluorescent MRI contrast agent behavior in the liver and thoracic aorta of mice. Edmond Kahn,Gérard Lizard,Dominique Dumas,Frédérique Frouin,Frank Ménétrieret al. Analytical and Quantitative Cytology and Histology, 2004, 26 (4), pp.233-8 Article dans une revue hal-00559067v1
Chronology of cellular alterations during 7-ketocholesterol-induced cell death on A7R5 rat smooth muscle cells: analysis by time lapse-video microscopy and conventional fluorescence microscopy. Jean-Marie Zahm,Sonia Baconnais,Serge Monier,Noël Bonnet,Ginette Bessèdeet al. Cytometry Part A, 2003, 52 (2), pp.57-69. ⟨10.1002/cyto.a.10027⟩ Article dans une revue inserm-00148786v1
Microbilles, nanobilles et cytométrie : applications à l’analyse et à la purification cellulaire et moléculaire G Lizard,L Duvillard,N Wedemeyer,C Muller,F Ghiringhelliet al. Pathologie Biologie, 2003, 51 (7), pp.418-427. ⟨10.1016/S0369-8114(03)00127-5⟩ Article dans une revue istex hal-04980086v1
Early mitochondrial dysfunction, superoxide anion production, and DNA degradation are associated with non-apoptotic death of human airway epithelial cells induced by Pseudomonas aeruginosa exotoxin A. Maria-Cristina Plotkowski,Helvécio Cc Póvoa,Jean-Marie Zahm,Gérard Lizard,Geraldo Mb Pereiraet al. American Journal of Respiratory Cell and Molecular Biology, 2002, 26 (5), pp.617-26 Article dans une revue inserm-00154288v1
Plasma phospholipid transfer protein prevents vascular endothelium dysfunction by delivering α-tocopherol to endothelial cells Catherine M Desrumaux,Valérie Deckert,Anne Athias,David Masson,Gérard Lizardet al. FASEB Journal, 1999, 13 (8), pp.883-892. ⟨10.1096/fasebj.13.8.883⟩ Article dans une revue hal-04207349v1
Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7á-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall G. Lizard,Sylvette Monier,Catherine Cordelet,L. Gesquière,V. Deckertet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 1999, 19, pp.1190-1200 Article dans une revue hal-02688564v1
Inhibition by Cholesterol Oxides of NO Release From Human Vascular Endothelial Cells Valérie Deckert,Annie Brunet,Frédérique Lantoine,Gérard Lizard,Elisabeth Millanvoye-Van Brusselet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 1998, 18 (7), pp.1054-1060. ⟨10.1161/01.atv.18.7.1054⟩ Article dans une revue hal-03936665v1
Induction of similar features of apoptosis in human and bovine vascular endothelial cells treated by 7-ketocholesterol G. Lizard,M. Moisant,Catherine Cordelet,Sylvette Monier,Philippe Gambertet al. Journal of Pathology, 1997, 183, pp.330-338 Article dans une revue hal-02688324v1
Apoptosis without decrease of cell DNA content Jean-Pierre Rouault,Sylvie Fournel,Laurent Genestier,Gérard Lizard,Monique Flacheret al. FEBS Letters, 1995, 367 (2), pp.188-192. ⟨10.1016/0014-5793(95)00532-E⟩ Article dans une revue hal-02998634v1
Application of laser scanning image cytometry for human chromosome microdissection and DNA analysis P. Métézeau,G. Tachdjian,H. Kiefer,L. Druart,V. Cacheuxet al. Journal de Physique IV Proceedings, 1994, 04 (C4), pp.C4-265-C4-268. ⟨10.1051/jp4:1994461⟩ Article dans une revue istex jpa-00252724v1
Human melanoma cell lines differ in their capacity to release ADP and aggregate platelets. H. Boukerche,O. Berthier-Vergnes,F. Penin,E. Tabone,G. Lizardet al. Br J Haematol, 1994, 87, pp.763-772 Article dans une revue hal-00313722v1
Prospective methods for human papillomavirus detection by fluorescent in situ hybridization and laser excitation G. Lizard,C. Souchier,Y. Chardonnet Journal de Physique IV Proceedings, 1994, 04 (C4), pp.C4-257-C4-260. ⟨10.1051/jp4:1994459⟩ Article dans une revue istex jpa-00252722v1
Human melanoma cell lines differ in their capacity to release ADP and aggregate platelets. H. Boukerche,O. Berthier-Vergnes,F. Penin,E. Tabone,G. Lizardet al. British Journal of Haematology, 1994, 87 (4), pp.763-72. ⟨10.1111/j.1365-2141.1994.tb06736.x⟩ Article dans une revue hal-00189850v1

Communication dans un congrès (3)

Prevention of Oxysterol-Induced Oxiapoptophagy with Mediterranean Oils: Nutritherapeutic Approach of Age-Related Diseases Gérard Lizard,Imen Ghzaiel,Samah Maaloul,Raoudha Abdellaoui,Smail Mezianeet al. Valorization of the Mediterranean Vegetal Biodiversity: Nutritional, Therapeutic and Biotechnologic Aspects, Adil El Midaoui; Jamaleddine Hafid; Fouad Seghrouchni; Norbert Latruffe; Gérard Lizard, Apr 2024, Marrakech, Morocco. pp.CA3 Communication dans un congrès hal-04854988v1
7-Ketocholesterol effects on survival and growth in Drosophila melanogaster Dehbia Abed-Vieillard,Serge Loquin,William J. Griffiths,Haithem Hamdoun,Anne Vejuxet al. 10. European Network for Oxysterol Research (ENOR) symposium, Sep 2021, Virtual meeting, France Communication dans un congrès hal-03448141v1
Assessment of the toxicity of cholesterol oxides on retinal pigment epithelial cultured cells Laure Malvitte,Thomas Montange,Corinne Joffre,Aline Vejux,Alain M. Bronet al. Association for Research in Vision and Ophthalmology Annual Congress, Apr 2006, Fort Lauderdale, United States Communication dans un congrès hal-02754354v1

Poster de conférence (7)

Neuroprotective Effects of the Neuropeptide ODN against Inflammatory, Oxidative Stress, and Neurodegenerative Disorders Induced by Obesity Mouna Sallemi,Yosra Hamdi,Gérard Lizard,Jérôme Leprince,Olfa Masmoudi 7th International Congress of Biochemistry and Microbiology Applied Technologies, Nov 2024, Hammamet, Tunisia. 2024 Poster de conférence hal-05169250v1
Protective and Neurotrophic Effects of octaDecaNeuropeptide (ODN) in in Vitro and in Vivo Models of Neurodegenerative Diseases Yosra Hamdi,Ikram Ghouili,S. Mashadani,Amine Bourzam,Amira Namsiet al. 7th International Congress of Biochemistry and Microbiology Applied Technologies, Nov 2024, Hammamet, Tunisia. 2024 Poster de conférence hal-05169249v1
Octadecaneuropeptide (ODN) Mediated miRNA Regulation: A Novel Scientific Approach to Protect against Cell Death and Neuroinflammation in a Cellular Model of Neurodegenerative Disease Amine Bourzam,Yosra Hamdi,Seyma Bahdoudi,Karthi Duraisamy,Mouna El Mehdiet al. 7. international congress of Biochemistry and Microbiology Applied Technologies, Nov 2024, Hammamet, Tunisia Poster de conférence hal-05169247v1
Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in Vitro and in Vivo Models of Neurodegenerative Diseases Yosra Hamdi,Tasnim Chagrani,Sada Al-Mashhadani,Ikram Ghouili,Jérôme Leprinceet al. 9th Conference of the Mediterranean Neuroscience Society, Oct 2023, Carthage, Tunisia Poster de conférence hal-05168092v1
Toxicity of Branched-Chain Fatty Acids in Conjunctival Cell Line Maxime Souchier,Corinne Joffre,Laurent Leclère,Bénédicte Buteau,Stéphane Grégoireet al. ARVO Annual Meeting, May 2007, Fort Lauderdale, United States. Association for Research in Vision and Ophthalmology, Investigative Ophthalmology and Visual Science, 48, pp.e-Abstract 5305, 2007, ARVO Annual Meeting Abstract Poster de conférence hal-02757603v1
Major sulfation pathway for resveratrol metabolism in human hepatic derived cells and resveratrol –dependent inducibility of conjugating enzymes. Perspective in nutritional prevention Allan Lançon,Nathalie Hanet,Brigitte Jannin,Dominique Delmas,Jean-Marie Heydelet al. European Partnership Meetings: Taste, Nutrition, Health, Jun 2007, Dijon, France Poster de conférence hal-03838370v1
Major sulfation pathway for resveratrol metabolism in human hepatic derived cells and resveratrol –dependent inducibility of conjugating enzymes. Perspective in nutritional prevention Allan Lançon,Nathalie Hanet,Brigitte Jannin,Dominique Delmas,Jean-Marie Heydelet al. 2. congrès international Santé et Nutrition VITAGORA, Mar 2007, Dijon, France Poster de conférence hal-03838598v1

Proceedings/Recueil des communications (1)

First International Symposium “Valorization of the Mediterranean Vegetal Biodiversity: Nutritional, Therapeutic and Biotechnologic Aspects”, 25–26 April 2024, Marrakech, Morocco [Meeting Report] Adil El Midaoui,Jamaleddine Hafid,Fouad Seghrouchni,Norbert Latruffe,Gérard Lizard Valorization of the Mediterranean Vegetal Biodiversity: Nutritional, Therapeutic and Biotechnologic Aspects, 2024 Proceedings/Recueil des communications hal-04820336v1

Chapitre d'ouvrage (5)

In Vitro Evaluation of the Effects of 7-Ketocholesterol and 7β-Hydroxycholesterol on the Peroxisomal Status: Prevention of Peroxisomal Damages and Concept of Pexotherapy Imen Ghzaiel,Samah Maaloul,Mohamed Ksila,Amira Namsi,Aline Yammineet al. Gérard Lizard. Implication of Oxysterols and Phytosterols in Aging and Human Diseases, 1440, Springer International Publishing, pp.437-452, 2024, Advances in Experimental Medicine and Biology (AEMB), 978-3-031-43883-7. ⟨10.1007/978-3-031-43883-7_21⟩ Chapitre d'ouvrage hal-04759802v1
Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers Mohamed Ksila,Imen Ghzaiel,Khouloud Sassi,Amira Zarrouk,Valerio Leoniet al. Gérard Lizard. Implication of Oxysterols and Phytosterols in Aging and Human Diseases, 1440, Springer International Publishing, pp.379-400, 2023, Advances in Experimental Medicine and Biology (AEMB), 978-3-031-43882-0, 978-3-031-43885-1, 978-3-031-43883-7. ⟨10.1007/978-3-031-43883-7_19⟩ Chapitre d'ouvrage hal-04843308v1
Chemical and Biochemical Features of Spinasterol and Schottenol Farid Khallouki,Mohamed Ksila,Imen Ghzaiel,Soukaina Essadek,Mounia Tahri Jouteyet al. Implication of Oxysterols and Phytosterols in Aging and Human Diseases, 1440, Springer International Publishing, pp.45-55, 2023, Advances in Experimental Medicine and Biology, 978-3-031-43883-7. ⟨10.1007/978-3-031-43883-7_3⟩ Chapitre d'ouvrage hal-04509752v1
7-ketocholesterol- and 7β-hydroxycholesterol-induced peroxisomal disorders in glial, microglial and neuronal cells: Potential role in neurodegeneration Thomas Nury,Aline Yammine,Franck Menetrier,Amira Zarrouk,Anne Vejuxet al. Gérard Lizard. Peroxisome Biology: Experimental Models, Peroxisomal Disorders and Neurological Diseases, 1299, Springer International Publishing, 2020, Advances in Experimental Medicine and Biology (AEMB), 978-3-030-60203-1 (print). ⟨10.1007/978-3-030-60204-8_3⟩ Chapitre d'ouvrage hal-03158086v1
Toxicological Risk Assessment of Emerging Nanomaterials: Cytotoxicity, Cellular Uptake, Effects on Biogenesis and Cell Organelle Activity, Acute Toxicity and Biodistribution of Oxide Nanoparticles Lionel Maurizi,Anne-Laure Papa,Julien Boudon,Sruthi Sudhakaran,Benoist Pruvotet al. Unraveling the Safety Profile of Nanoscale Particles and Materials-From Biomedical to Environmental Applications, InTech, 2018, ⟨10.5772/intechopen.71833⟩ Chapitre d'ouvrage hal-02163546v1

Autre publication scientifique (1)

Benefits of Argan Oil on Human Health—May 4–6 2017, Errachidia, Morocco Gérard Lizard,Younes Filali-Zegzouti,Adil El Midaoui 2017, pp.1383. ⟨10.3390/ijms18071383⟩ Autre publication scientifique inserm-01552936v1