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Ghislaine Guillemain

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Targeting hIAPP fibrillation: A new paradigm to prevent β-cell death?

Ghislaine Guillemain , Jean-Jacques Lacapere , Lucie Khemtemourian
Biochimica et Biophysica Acta:Biomembranes, 2022, 1864 (10), pp.184002. ⟨10.1016/j.bbamem.2022.184002⟩
Article dans une revue hal-03818261v1
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Molecular Mechanisms of Glucocorticoid-Induced Insulin Resistance

Carine Beaupere , Alexandrine Liboz , Bruno Fève , Bertrand Blondeau , Ghislaine Guillemain
International Journal of Molecular Sciences, 2021, 22 (2), pp.623. ⟨10.3390/ijms22020623⟩
Article dans une revue hal-03110516v1
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The flanking peptides issue from the maturation of the human islet amyloid polypeptide (hIAPP) slightly modulate hIAPP-fibril formation but not hIAPP-induced cell death

Shadai Salazar Vazquez , Bertrand Blondeau , Pierre Cattan , Mathieu Armanet , Ghislaine Guillemain
Biochimie, 2020, 170, pp.26-35. ⟨10.1016/j.biochi.2019.12.005⟩
Article dans une revue hal-02998171v1
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Adaptive β-Cell Neogenesis in the Adult Mouse in Response to Glucocorticoid-Induced Insulin Resistance

Emilie Courty , Adrien Besseiche , Thi Thu Huong Do , Alexandrine Liboz , Fatima Mohamed Aguid
Diabetes, 2018, 68 (1), pp.95-108. ⟨10.2337/db17-1314⟩
Article dans une revue hal-02295604v1

Residue specific effects of human islet polypeptide amyloid on self-assembly and on cell toxicity

Lucie Khemtémourian , Ghislaine Guillemain , Fabienne Foufelle , J. Antoinette Killian
Biochimie, 2017, 142, pp.22-30. ⟨10.1016/j.biochi.2017.07.015⟩
Article dans une revue hal-02342099v1
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Glucocorticoids Inhibit Basal and Hormone-Induced Serotonin Synthesis in Pancreatic Beta Cells

Moina Hasni Ebou , Amrit Singh-Estivalet , Jean-Marie Launay , Jacques Callebert , François Tronche
PLoS ONE, 2016, 11 (2), pp.e0149343. ⟨10.1371/journal.pone.0149343⟩
Article dans une revue hal-01281984v1

Glucose Tolerance Is Improved in Mice Invalidated for the Nuclear Receptor HNF-4γ: A Critical Role for Enteroendocrine Cell Lineage.

Floriane Baraille , Sami Ayari , Véronique Carrière , Céline Osinski , Kevin Garbin
Diabetes, 2015, 64 (8), pp.2744. ⟨10.2337/db14-0993⟩
Article dans une revue hal-03990038v1

Mutations in SLC2A2 Gene Reveal hGLUT2 Function in Pancreatic β Cell Development

Aurelien Michau , Ghislaine Guillemain , Alexandra Grosfeld , Sandrine Vuillaumier-Barrot , Teddy Grand
Journal of Biological Chemistry, 2013, 288 (43), pp.31080-31092. ⟨10.1074/jbc.M113.469189⟩
Article dans une revue hal-02265470v1

Activation of the transcription factor carbohydrate-responsive element-binding protein by glucose leads to increased pancreatic beta cell differentiation in rats

A. Soggia , K. Flosseau , P. Ravassard , G. Szinnai , Raphaël Scharfmann
Diabetologia, 2012, 55 (10), pp.2713-2722. ⟨10.1007/s00125-012-2623-0⟩
Article dans une revue hal-03990076v1

The Hexosamine Biosynthesis Pathway Is Essential for Pancreatic Beta Cell Development

Gaëlle Filhoulaud , Ghislaine Guillemain , Raphaël Scharfmann
Journal of Biological Chemistry, 2009, 284 (36), pp.24583-24594. ⟨10.1074/jbc.M109.025288⟩
Article dans une revue hal-03990084v1

β-cell development: the role of intercellular signals

R. Scharfmann , B. Duvillie , V. Stetsyuk , M. Attali , G. Filhoulaud
Diabetes, Obesity and Metabolism, 2008, 10, pp.195-200. ⟨10.1111/j.1463-1326.2008.00953.x⟩
Article dans une revue hal-03990092v1

Control of pancreatic development by intercellular signals

Bertrand Duvillié , Volodymyr Stetsyuk , Gaëlle Filhoulaud , Ghislaine Guillemain , Raphaël Scharfmann
Biochemical Society Transactions, 2008, 36 (3), pp.276-279. ⟨10.1042/BST0360276⟩
Article dans une revue hal-03990096v1

Glucose Is Necessary for Embryonic Pancreatic Endocrine Cell Differentiation

Ghislaine Guillemain , Gaëlle Filhoulaud , Gabriela da Silva-Xavier , Guy Rutter , Raphaeöl Scharfmann
Journal of Biological Chemistry, 2007, 282 (20), pp.15228-15237. ⟨10.1074/jbc.M610986200⟩
Article dans une revue hal-03990103v1

Mechanisms of Checkpoint Kinase Rad53 Inactivation after a Double-Strand Break in Saccharomyces cerevisiae

Ghislaine Guillemain , Emilie Ma , Sarah Mauger , Simona Miron , Robert Thai
Molecular and Cellular Biology, 2007, 27 (9), pp.3378-3389. ⟨10.1128/MCB.00863-06⟩
Article dans une revue hal-03990108v1

Mechanisms of checkpoint kinase Rad53 inactivation after a double-strand break in Saccharomyces cerevisiae

G. Guillemain , E. Ma , S. Mauger , S. Miron , R. Thai
Molecular and Cellular Biology, 2007, pp.3378-3389
Article dans une revue hal-00259219v1

A Karyopherin α2 Nuclear Transport Pathway is Regulated by Glucose in Hepatic and Pancreatic Cells

Aurélia Cassany , Ghislaine Guillemain , Christophe Klein , Véronique Dalet , Edith Brot-Laroche
Traffic, 2004, 5 (1), pp.10-19. ⟨10.1046/j.1398-9219.2003.0143.x⟩
Article dans une revue hal-03990126v1

Importin beta1 mediates the glucose-stimulated nuclear import of pancreatic and duodenal homeobox-1 in pancreatic islet beta-cells (MIN6)

Ghislaine Guillemain , Gabriela da Silva Xavier , Imran Rafiq , Armelle Leturque , Guy Rutter
Biochemical Journal, 2004, 378 (1), pp.219-227. ⟨10.1042/BJ20031549⟩
Article dans une revue hal-03990135v1

Karyopherin α2: a control step of glucose-sensitive gene expression in hepatic cells

Ghislaine Guillemain , Maria Muñoz-Alonso , Aurélia Cassany , Martine Loizeau , Anne-Marie Faussat
Biochemical Journal, 2002, 364 (1), pp.201-209. ⟨10.1042/bj3640201⟩
Article dans une revue hal-03990142v1

The large intracytoplasmic loop of the glucose transporter GLUT2 is involved in glucose signaling in hepatic cells

G. Guillemain , M. Loizeau , M. Pincon-Raymond , J. Girard , A. Leturque
Journal of Cell Science, 2000, 113 (5), pp.841-847. ⟨10.1242/jcs.113.5.841⟩
Article dans une revue hal-03990196v1

A Novel Cytosolic Dual Specificity Phosphatase, Interacting with Glucokinase, Increases Glucose Phosphorylation Rate

Maria Muñoz-Alonso , Ghislaine Guillemain , Nadim Kassis , Jean Girard , Anne-Françoise Burnol
Journal of Biological Chemistry, 2000, 275 (42), pp.32406-32412. ⟨10.1074/jbc.M000841200⟩
Article dans une revue hal-03990170v1