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A single‐domain intrabody targeting the follicle‐stimulating hormone receptor impacts FSH ‐induced G protein‐dependent signalling

Pauline Raynaud , Vinesh Jugnarain , Océane Vaugrente , Amandine Vallet , Thomas Boulo
FEBS Letters, 2024, 598 (2), pp.220-232. ⟨10.1002/1873-3468.14765⟩
Journal articles hal-04564581v1
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An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis

Camille Gauthier , Pauline Raynaud , Frédéric Jean-Alphonse , Amandine Vallet , Océane Vaugrente
Molecular and Cellular Endocrinology, 2024, 589, pp.112235. ⟨10.1016/j.mce.2024.112235⟩
Journal articles hal-04564514v1
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Combined multiplexed phage display, high-throughput sequencing, and functional assays as a platform for identifying modulatory VHHs targeting the FSHR

Anielka Zehnaker , Amandine Vallet , Juliette Gourdon , Caterina Sarti , Vinesh Jugnarain
International Journal of Molecular Sciences, 2023, 24 (21), pp.15961. ⟨10.3390/ijms242115961⟩
Journal articles hal-04274818v1
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A New in Silico antibody similarity measure both identifies large sets of epitope binders with distinct CDRs and accurately predicts off-target reactivity

Astrid Musnier , Thomas Bourquard , Amandine Vallet , Laetitia Mathias , Gilles Bruneau
International Journal of Molecular Sciences, 2022, 23 (17), pp.1-17. ⟨10.3390/ijms23179765⟩
Journal articles hal-03838203v1
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Accurate determination of epitope for antibodies with unknown 3D structures

Shifa Tahir , Thomas Bourquard , Astrid Musnier , Yann Jullian , Yannick Corde
mAbs, 2021, 13 (1), pp.1-10. ⟨10.1080/19420862.2021.1961349⟩
Journal articles hal-03390655v1
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Biased signaling and allosteric modulation at the FSHR

Flavie Landomiel , Francesco de Pascali , Pauline Raynaud , Frédéric Jean-Alphonse , Romain Yvinec
Frontiers in Endocrinology, 2019, 10, pp.148. ⟨10.3389/fendo.2019.00148⟩
Journal articles hal-02362523v1
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MAbTope: A Method for Improved Epitope Mapping

Thomas Bourquard , Astrid Musnier , Vincent Puard , Shifa Tahir , Mohammed Akli Ayoub
Journal of Immunology, 2018, 201 (10), pp.3096-3105. ⟨10.4049/jimmunol.1701722⟩
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G protein-dependent signaling triggers a β-arrestin-scaffolded p70S6K/ rpS6 module that controls 5'TOP mRNA translation

Aurélie Trefier , Astrid Musnier , Flavie Landomiel , Thomas Bourquard , Thomas Boulo
FASEB Journal, 2018, 32 (3), pp.1154-1169. ⟨10.1096/fj.201700763R⟩
Journal articles hal-02620979v1
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β-arrestin signalling and bias in hormone-responsive GPCRs

Eric Reiter , Mohammed Akli Ayoub , Lucie P. Pellissier , Flavie Landomiel , Astrid Musnier
Molecular and Cellular Endocrinology, 2017, 449, pp.28-41. ⟨10.1016/j.mce.2017.01.052⟩
Journal articles hal-01604784v1

Evidence that histaminergic neurons are devoid of estrogen receptor alpha in the ewe diencephalon during the breeding season

Gilles Bruneau , Martine Batailler , Maya Belghazi , Yves Tillet , Michel Blanc
General and Comparative Endocrinology, 2014, 199, pp.86-93. ⟨10.1016/j.ygcen.2014.01.007⟩
Journal articles hal-01129801v1

Selection and characterization of recombinant dromedary antiovalbumin antibody fragments that do not cross-react with ovalbumin-related protein x: use for immunoaffinity

Gilles Bruneau , Abdelhaq Anouassi , Sophie Réhault-Godbert , Sylvie Canepa , Michel Blanc
Journal of Agricultural and Food Chemistry, 2012, 60 (49), pp.12157-12163. ⟨10.1021/jf303053t⟩
Journal articles hal-01129680v1

Hypothalamic arcuate neuropeptide Y-neurons decrease periventricular somatostatin-neuronal activity before puberty in the female lamb: morphological arguments

Yves Tillet , Sophie Picard , Gilles Bruneau , P. Ciofi , M. Wankowska
Journal of Chemical Neuroanatomy, 2010, 40 (4), pp.265-271. ⟨10.1016/j.jchemneu.2010.07.003⟩
Journal articles hal-01129470v1

Is there a leptin gene in the chicken genome? Lessons from phylogenetics, bioinformatics and genomics

Frederique Pitel , Thomas Faraut , Gilles Bruneau , Philippe Monget
General and Comparative Endocrinology, 2010, 167 (1), pp.1-5. ⟨10.1016/j.ygcen.2009.10.006⟩
Journal articles hal-01129469v1

A new method to discriminate immunogen-specific heavy-chain homodimer from heterotetramer immunoglobulin G directly in immunized dromedary whole plasma proteins: Western ligand blotting

Michel Blanc , A. Anouassi , M.A. Abed , Sylvie Canepa , Valérie Labas
Veterinary Immunology and Immunopathology, 2009, 127 (3-4), pp.340-349. ⟨10.1016/j.vetimm.2008.10.334⟩
Journal articles hal-02664384v1

A one-step exclusion-binding procedure for the purification of functional heavy-chain and mammalian-type gamma-globulins from camelid sera

Michel Blanc , A. Anouassi , Muhanad Ahmed Abed , Guillaume Tsikis , Sylvie Canepa
Biotechnology and Applied Biochemistry, 2009, 54 (4), pp.207-212. ⟨10.1042/BA20090208⟩
Journal articles hal-02660837v1

Prepubertal changes in the synthesis, storage and release of the somatostatin in the hypothalamus of female lambs. A morphofunctional study

Jolanta Polkowska , A. Wojcik- Gladysz , Marta Wankowska , Gilles Bruneau , Yves Tillet
Journal of Chemical Neuroanatomy, 2008, 36 (1), pp.53-58. ⟨10.1016/j.jchemneu.2008.05.007⟩
Journal articles hal-02668254v1

Regulation by Estradiol of Hypothalamic Somatostatin Gene Expression: Possible Involvement of Somatostatin in the Control of Luteinizing Hormone Secretion in the Ewe

Delphine Pillon , Alain Caraty , Claude Fabre-Nys , Didier Lomet , Marilyn Cateau
Biology of Reproduction, 2004, 71 (1), pp.38-44. ⟨10.1095/biolreprod.103.023689⟩
Journal articles hal-03157344v1

Prolonged neurogenesis during early development of gonadotropin-releasing hormone neurones in sheep (ovis aries) : in vivo and in vitro studies

Gilles Bruneau , M. Izvolskaia , M. Ugrumov , Yves Tillet , Anne Duittoz
Neuroendocrinology, 2003, 77, pp.177-186
Journal articles hal-02675978v1

Resistant ribonuclease activity in preparations of total RNA extracted from artiodactyl brain with GITC

Delphine Pillon , Gilles Bruneau
Biotechniques, 2003, 34, pp.920-924
Journal articles hal-02676009v1

Short-term effect of oestradiol on neurokinin B mRNA expression in the infundibular nucleus of ewes

Delphine Pillon , Alain Caraty , Claude Fabre-Nys , Gilles Bruneau
Journal of Neuroendocrinology, 2003, 15, pp.749-753
Journal articles hal-02675971v1

Early decrease of proopiomelanocortin but not neuropeptide Y mRNA expression in the mediobasal hypothalamus of the ewe, during the estradiol-induced preovulatory LH surge

Delphine Pillon , Alain Caraty , Claude Fabre-Nys , Gilles Bruneau
General and Comparative Endocrinology, 2003, 134, pp.264-272
Journal articles hal-02675820v1

Prolonged Neurogenesis during Early Development of Gonadotropin-Releasing Hormone Neurones in Sheep (Ovis aries): In vivo and in vitro Studies

Gilles Bruneau , M. Izvolskaia , M. Ugrumov , Yves Tillet , Anne Duittoz
Neuroendocrinology, 2003, 77 (3), pp.177-186. ⟨10.1159/000069505⟩
Journal articles hal-02527310v1
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Sous-nutrition, reproduction et systèmes nerveux central chez les mammifères : rôle de la leptine

Philippe Chemineau , M. Blanc , Alain Caraty , Gilles Bruneau , Philippe Monget
Productions Animales, 1999, 12 (3), pp.217-223
Journal articles hal-02683987v1

La leptine: une clé pour la reproduction

Gilles Bruneau , C. Vaisse , Alain Caraty , Philippe Monget
Médecine/Sciences, 1999, 15, pp.191-196
Journal articles hal-02689721v1

Les interactions métabolisme-reproduction chez les animaux domestiques

Philippe Monget , Alain Caraty , Gilles Bruneau , G.B. Martin
Contraception Fertilité Sexualité, 1998, 26 (7-8), pp.554-563
Journal articles hal-02698684v1

Localization of the preprosomatostatin-mRNA by in situ hybridization in the ewe hypothalamus

Gilles Bruneau , Yves Tillet
Peptides, 1998, 19 (10), pp.1749-1758
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Evidence that the mediobasal hypothalamus is the primary site of action of estradiol in inducing the preovulatory gonadotropin releasing hormone surge in the ewe

Alain Caraty , Claude Fabre-Nys , Bernadette Delaleu , Aude Locatelli , Gilles Bruneau
Endocrinology, 1998, 139 (4), pp.1752-1760
Journal articles hal-02687666v1

Chromosomal localization of the human and mouse histidine decarboxylase genes by in situ hybridization. Exclusion of the HDC gene from the Prader-Willi syndrome region

P. Malzac , M.G. Mattei , J. Thibault , Gilles Bruneau
Human Genetics, 1996, 97, pp.359-361
Journal articles hal-02695364v1

Effect of interleukin-1 receptor antagonist (IL-1RA) on histamine and serotonin release by rat basophilic leukemia cells (RBL-2H3) and peritoneal mast cells

Pio Conti , William Bouchet , Claudio Feliciani , Sandra Mammarella , Leena Kudchadker
Molecular and Cellular Biochemistry, 1996, 155 (1), pp.61-68. ⟨10.1007/BF00714334⟩
Journal articles hal-02699261v1

Monocyte chemotactic protein-1 provokes mast cell aggregation and [3H]5HT release.

P Conti , W Boucher , R Letourneau , C Feliciani , M Reale
Immunology, 1995, 86 (3), pp.434-440
Journal articles hal-02712161v1

Le contrôle neuroendocrinien de l'ovulation chez la brebis

Alain Caraty , F.J. Krasch , Allan Edward Herbison , Gilles Bruneau , Bernadette Delaleu
Annales d'Endocrinologie = Annals of Endocrinology, 1995, 56, pp.539-542
Journal articles hal-02712342v1

Exclusion of two candidate genes, Spnb-2 and Ddc, for the wobbler spinal muscular atrophy gene on proximal mouse Chromosome 11

A. Lengeling , W. E. Zimmer , S. R. Goodman , Y. Ma , M. L. Bloom
Mammalian Genome, 1994, 5 (3), pp.163-166. ⟨10.1007/BF00352348⟩
Journal articles hal-02711942v1

Assignment of the rat genes coding for DOPA decarboxylase (DDC) and glutamic acid decarboxylases (GAD1 and GAD2)

Cécile Vassort , Michel Rivière , Gilles Bruneau , François Gros , Jean Thibault
Mammalian Genome, 1993, 4 (4), pp.202-206. ⟨10.1007/BF00417563⟩
Journal articles hal-02715991v1

Preparation of a rat brain histidine decarboxylase (HDC) cDNA probe by PCR and assignment of the human HDC gene to chromosome 15

Gilles Bruneau , van Cong Nguyen , François Gros , Alain Bernheim , Jean Thibault
Human Genetics, 1992, 90 (3), pp.235-238. ⟨10.1007/BF00220068⟩
Journal articles hal-02711941v1

Mapping of the DOPA decarboxylase gene to the 11A band of the murine genome

Gilles Bruneau , Jean Thibault , François Gros , Marie-Geneviève Mattei
Biochemical and Biophysical Research Communications, 1992, 186 (2), pp.926-930. ⟨10.1016/0006-291X(92)90834-8⟩
Journal articles hal-02715993v1

Preparation of a human DOPA decarboxylase cDNA probe by PCR and its assignment to chromosome 7.

Gilles Bruneau , M.S. Gross , M Krieger , Alain Bernhein , Jean Thibault
Annales de génétique, 1990, 33 (4), pp.208-213
Journal articles hal-02711939v1

Characterization of DOPA decarboxylase mRNA in rat pheochromocytoma.

Gilles Bruneau , Monique Krieger-Poullet , Francis Cogé , Carla Borri-Voltattorni , François Gros
Biochimie, 1990, 72 (1), pp.73-76. ⟨10.1016/0300-9084(90)90175-G⟩
Journal articles hal-02713964v1