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Guilhem Pages
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Documents
Identifiants chercheurs
- guilhem-pages
- ResearcherId : B-5422-2010
- 0000-0001-9368-5237
- IdRef : 113522290
Présentation
### **RESEARCH EXPERIENCE**
**Since AgroResonance platform, UR370 QuaPA**, INRA, Saint-Genès-Champanelle, France
**2014/10** *Research engineer*
· Optimize and write NMR/MRI methods and protocols to match customer requirements
· Develop *in-situ* low-field NMR
· Work under ISO 9001 management system
**2014/03 Biomedical NMR Group UMR 5068**, Paul Sabatier University, Toulouse, France
**2014/09** *Postdoctoral researcher in Professor M. Malet-Martino’s group*
· Optimized diffusion NMR data acquisition to deformulate complex mixtures
· Characterized adulteration in supplement diets by benchtop NMR
**2011/02 Singapore BioImaging Consortium**, A\*STAR, Singapore
**2014/02** *Senior research fellow*
· Characterised *in-vivo* and *in-vitro* biological pathways by Dynamic Nuclear Polarization (DNP) NMR
· Modelized biological pathways to estimate kinetic parameters from DNP experimental data
· Studied brain activity by Gluco-CEST
· Maintained the NMR spectrometer
**2010/02 Physical Chemistry Department**, Royal Institute of Technology (KTH), Stockholm, Sweden
**2011/01** *Postdoctoral researcher in Professor I. Furò’s group*
· Measured and explained water diffusion in wood
· Characterised interactions between wood and oil
· Developed pulse sequence for diffusion measurements in complex system
**2007/01 School of Molecular and Microbial Biosciences**, University of Sydney, Sydney, Australia
**2009/12** *Postdoctoral researcher in Professor P. W. Kuchel’s group*
· Implemented fast diffusion pulse sequences to study erythrocyte shape evolution
· Studied starch digestion by NMR and electrophoretic NMR
· Characterised peptide structure (hERG, TASK2)
· Developed NMR pulse sequence
**2003/10 Research unit JE 2421 TRACES**, Paul Cézanne University, Marseille, France
**2006/10** *Post-graduate student.*
· Developed a new NMR technique that improves the resolution of NMR diffusion experiments: “Chromatographic NMR”
· Optimized HPLC assay of Saint John’s Wort’s naphthodianthrones
· Maintenance and troubleshooting of spectrometers and HPLC equipment
**2002/09 Pharmaceutical laboratory DistriB3**, Marseille, France
**2003/09** *Laboratory technician.*
· Identified plants and determined active principles using Pharmacopoeia monographs
· Developed analytical methods
**2002/02 Synthesis, Catalysis and Chirality Laboratory**, Paul Cézanne University, Marseille
**2002/08** *Graduate student*, MS training period.
· Synthesized chromatographic phase and characterized them by IR and Solid state NMR
**2001/07 Sanofi~Synthélabo**, Process development laboratory, Montpellier, France
**2001/10** *Laboratory student*, BS training period.
· Developed and extrapolated a drug synthesis
· Synthesized in the preproduction unit
**1999/04 Pierre Fabre**, Industrial and chemical development center, Gaillac, France
**1999/07** *Laboratory student*, Training period.
· Optimized the synthesis of an active molecule
### **GRANTS & AWARDS**
- **French research national agency (ANR),** 2019 (4y, € 487 528)
*OutLabMRI: A unique MR imager outside the laboratory : new horizons in agro-ecosystems*
- **I-SITE CAP 20-25, PhD grant,** 2018 (3y, € 90 000)
*Développement et validation d’un nouveau capteur pour mesurer* in situ *et localement les quantités et flux d’eau dans les agroécosystèmes*
- **I-SITE CAP 20-25 EMERGENCE,** 2018 (1y, € 30 000)
*Augmenter la sensibilité de l’imagerie du 13C hyperpolarisé par polarisation croisée : premières démonstrations* in vivo
- **Ligue régionale contre le cancer,** 2016 (2y, € 40 000)
*Développement d’une méthode d’imagerie innovante contrastant les caractéristiques du microenvironnement du chondrosarcome: diagnostic et suivi de nouvelles prodrogues bispécifiques*
- **Joint Council Office Exploratory Grant,** 2013 (1y, SGD$ 133 000)
*Enabling multi-nuclear dynamic nuclear polarization - nuclear magnetic resonance (DNP-NMR)*
- **University of Sydney Bridging Support Grant,** 2009 (1y, AUS$ 20 000)
*NMR diffusion and exchange spectroscopy for studying chemical transformation in heterogeneous biochemical systems*
- **Magnetic Resonance in Chemistry Award for young scientist,** 2006 (1500 €)
- **3rd poster prize** (2 books) in Chemometric 2005 congress
- **3-years PhD grant** (2003-2006) from the French Conseil Régional de Provence-Alpes-Côte d’Azur
### **EDUCATION**
- **HDR, 2019,** University Clermont Auvergne, Clermont-Ferrand, France
*“IRM: du laboratoire au champ”*
- **PhD in Physical Chemistry, 2006,** University Paul Cézanne, Marseille, France
*“Chromatographic NMR”*
Supervisor: Professor Stefano Caldarelli
- **Engineering degree, 2002,** University Paul Cézanne, Marseille, France
National Higher School of Chemical Synthesis, Process and Engineering (ENSSPICAM)
- **MS** **in organic chemistry, 2002,** University Paul Cézanne, Marseille, France
*A new chromatographic phase based on cholesterol ether. Synthesis and characterization.*
Publications
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Circadian Variation of Root Water Status in Three Herbaceous Species Assessed by Portable NMRPlants, 2021, 10 (4), ⟨10.3390/plants10040782⟩
Article dans une revue
hal-03200198v1
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Can NMR become a tool of choice to study ecosystems directly in the fields?Compact NMR conference II, Oct 2021, Online, France
Communication dans un congrès
hal-03419138v1
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Assessment of the sensitivity of a low-field NMR sensor by characterizing root water status of an herbaceous plant under drought conditionsCompact NMR Conference II, Oct 2021, Nantes, France
Communication dans un congrès
hal-03377468v1
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État hydrique des racines de plantes prairiales évalué par RMN portableGERM, Apr 2021, Online, France
Communication dans un congrès
hal-03377555v1
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La RMN portable pour caractériser les racines de plantes prairialesJournées du Grand Sud, Jul 2021, CLERMONT-FERRAND, France. 2021
Poster de conférence
hal-03347761v1
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LA RMN PORTABLE POUR CARACTERISER LES RACINES DE PLANTES PRAIRIALESJournées RMN du Grand Sud, Jul 2021, Clermont-Ferrand, France
Poster de conférence
hal-03331827v1
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