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Guilhem Pages

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Identifiants chercheurs

Présentation

### **RESEARCH EXPERIENCE** **Since AgroResonance platform, UR370 QuaPA**, INRA, Saint-Genès-Champanelle, France **2014/10** *Research engineer* · Optimize and write NMR/MRI methods and protocols to match customer requirements · Develop *in-situ* low-field NMR · Work under ISO 9001 management system **2014/03 Biomedical NMR Group UMR 5068**, Paul Sabatier University, Toulouse, France **2014/09** *Postdoctoral researcher in Professor M. Malet-Martino’s group* · Optimized diffusion NMR data acquisition to deformulate complex mixtures · Characterized adulteration in supplement diets by benchtop NMR **2011/02 Singapore BioImaging Consortium**, A\*STAR, Singapore **2014/02** *Senior research fellow* · Characterised *in-vivo* and *in-vitro* biological pathways by Dynamic Nuclear Polarization (DNP) NMR · Modelized biological pathways to estimate kinetic parameters from DNP experimental data · Studied brain activity by Gluco-CEST · Maintained the NMR spectrometer **2010/02 Physical Chemistry Department**, Royal Institute of Technology (KTH), Stockholm, Sweden **2011/01** *Postdoctoral researcher in Professor I. Furò’s group* · Measured and explained water diffusion in wood · Characterised interactions between wood and oil · Developed pulse sequence for diffusion measurements in complex system **2007/01 School of Molecular and Microbial Biosciences**, University of Sydney, Sydney, Australia **2009/12** *Postdoctoral researcher in Professor P. W. Kuchel’s group* · Implemented fast diffusion pulse sequences to study erythrocyte shape evolution · Studied starch digestion by NMR and electrophoretic NMR · Characterised peptide structure (hERG, TASK2) · Developed NMR pulse sequence **2003/10 Research unit JE 2421 TRACES**, Paul Cézanne University, Marseille, France **2006/10** *Post-graduate student.* · Developed a new NMR technique that improves the resolution of NMR diffusion experiments: “Chromatographic NMR” · Optimized HPLC assay of Saint John’s Wort’s naphthodianthrones · Maintenance and troubleshooting of spectrometers and HPLC equipment **2002/09 Pharmaceutical laboratory DistriB3**, Marseille, France **2003/09** *Laboratory technician.* · Identified plants and determined active principles using Pharmacopoeia monographs · Developed analytical methods **2002/02 Synthesis, Catalysis and Chirality Laboratory**, Paul Cézanne University, Marseille **2002/08** *Graduate student*, MS training period. · Synthesized chromatographic phase and characterized them by IR and Solid state NMR **2001/07 Sanofi~Synthélabo**, Process development laboratory, Montpellier, France **2001/10** *Laboratory student*, BS training period. · Developed and extrapolated a drug synthesis · Synthesized in the preproduction unit **1999/04 Pierre Fabre**, Industrial and chemical development center, Gaillac, France **1999/07** *Laboratory student*, Training period. · Optimized the synthesis of an active molecule ### **GRANTS & AWARDS** - **French research national agency (ANR),** 2019 (4y, € 487 528) *OutLabMRI: A unique MR imager outside the laboratory : new horizons in agro-ecosystems* - **I-SITE CAP 20-25, PhD grant,** 2018 (3y, € 90 000) *Développement et validation d’un nouveau capteur pour mesurer* in situ *et localement les quantités et flux d’eau dans les agroécosystèmes* - **I-SITE CAP 20-25 EMERGENCE,** 2018 (1y, € 30 000) *Augmenter la sensibilité de l’imagerie du 13C hyperpolarisé par polarisation croisée : premières démonstrations* in vivo - **Ligue régionale contre le cancer,** 2016 (2y, € 40 000) *Développement d’une méthode d’imagerie innovante contrastant les caractéristiques du microenvironnement du chondrosarcome: diagnostic et suivi de nouvelles prodrogues bispécifiques* - **Joint Council Office Exploratory Grant,** 2013 (1y, SGD$ 133 000) *Enabling multi-nuclear dynamic nuclear polarization - nuclear magnetic resonance (DNP-NMR)* - **University of Sydney Bridging Support Grant,** 2009 (1y, AUS$ 20 000) *NMR diffusion and exchange spectroscopy for studying chemical transformation in heterogeneous biochemical systems* - **Magnetic Resonance in Chemistry Award for young scientist,** 2006 (1500 €) - **3rd poster prize** (2 books) in Chemometric 2005 congress - **3-years PhD grant** (2003-2006) from the French Conseil Régional de Provence-Alpes-Côte d’Azur ### **EDUCATION** - **HDR, 2019,** University Clermont Auvergne, Clermont-Ferrand, France *“IRM: du laboratoire au champ”* - **PhD in Physical Chemistry, 2006,** University Paul Cézanne, Marseille, France *“Chromatographic NMR”* Supervisor: Professor Stefano Caldarelli - **Engineering degree, 2002,** University Paul Cézanne, Marseille, France National Higher School of Chemical Synthesis, Process and Engineering (ENSSPICAM) - **MS** **in organic chemistry, 2002,** University Paul Cézanne, Marseille, France *A new chromatographic phase based on cholesterol ether. Synthesis and characterization.*

Publications

50454
Image document

Can metabolic mri be useful to image tomato metabolism?

Guilhem Pagès , Catherine Deborde , Martine Lemaire-Chamley , Moing A Lemaire-Chamley , J.-M. Bonny
International Plant Spectroscopy Conference (IPSC), Sep 2022, Nantes, France
Communication dans un congrès hal-03781345v1