Guillaume Moissiard PI of Epi2Trans team at LGDP in Perpignan

Identifiants chercheurs

IdHAL :

guillaume-moissiard

ORCID :

0000-0002-9532-6876

IdRef :

131278150

Présentation

Our team studies epigenetic pathways and chromatin factors regulating gene expression and repressing transposable elements (TEs). We are also characterizing the function of TE genes that have been exapted – also known as coopted or domesticated – by the plants. These genes, called exapted TE (ETE) genes can be of different origins, forming distinct gene families such as the Plant Mobile Domain, the MUSTANG or the SLEEPER families. Finally, we are studying the impact of TEs on transcriptomic diversity in plants subjected to abiotic stresses such as heat to understand how TEs can contribute to plant adaptation in response to environmental stresses.Our research is done in Arabidopsis and tomato, two plant species displaying very different genome organizations. We combine Illumina short-read and Oxford Nanopore technologies (ONT) long-read sequencing to study differential gene expression, full length RNA diversity, structural variations and epigenetic modifications. We use biochemical approaches to study chromatin/protein interaction (ChIP-seq) and protein interaction (IP-MS, CLNIP-MS, Co-IP, FPLC…)

Publications

Article dans une revue (6)

Plant mobile domain protein–DNA motif modules counteract Polycomb silencing to stabilize gene expression Thierry Pélissier,Lucas Jarry,Margaux Olivier,Gabin Dajoux,Marie-Noëlle Pouch-Pélissieret al. Nature Plants, In press, Online ahead of print. ⟨10.1038/s41477-025-02127-1⟩ Article dans une revue hal-05343329v1
Plant mobile domain proteins ensure Microrchidia 1 expression to fulfill transposon silencing Lucas Jarry,Julie Descombin,Melody Nicolau,Ange Dussutour,Nathalie Picaultet al. Life Science Alliance, 2023, 6 (4), pp.e202201539. ⟨10.26508/lsa.202201539⟩ Article dans une revue hal-04038933v1
Editorial: Plant epigenetics and chromatin dynamics - EPIPLANT 2021-2022 Guillaume Moissiard,Marie Mirouze,Cristel Carles,Clémentine Vitte Frontiers in Plant Science, 2023, 14, ⟨10.3389/fpls.2023.1260391⟩ Article dans une revue hal-04305976v1
The Evolutionary Volte-Face of Transposable Elements: From Harmful Jumping Genes to Major Drivers of Genetic Innovation Melody Nicolau,Nathalie Picault,Guillaume Moissiard Cells, 2021, 10 (11), pp.2952. ⟨10.3390/cells10112952⟩ Article dans une revue (article de synthèse) hal-03426512v1
The plant mobile domain proteins MAIN and MAIL1 interact with the phosphatase PP7L to regulate gene expression and silence transposable elements in Arabidopsis thaliana Melody Nicolau,Nathalie Picault,Julie Descombin,Yasaman Jami-Alahmadi,Suhua Fenget al. PLoS Genetics, 2020, 16 (4), pp.e1008324. ⟨10.1371/journal.pgen.1008324⟩ Article dans une revue hal-02561768v1
Involvement of a Jumonji‐C domain‐containing histone demethylase in DRM2‐mediated maintenance of DNA methylation Angelique Deleris,Maxim Greenberg,Israel Ausin,Rona Law,Guillaume Moissiardet al. EMBO Reports, 2010, 11 (12), pp.950-955. ⟨10.1038/embor.2010.158⟩ Article dans une revue hal-03439089v1

Pré-publication, Document de travail (1)

Plant Mobile Domain protein-DNA motif modules counteract Polycomb silencing to stabilize gene expression Thierry Pélissier,Lucas Jarry,Margaux Olivier,Gabin Dajoux,Marie-Noëlle Pouch- Pélissieret al. 2024 Pré-publication, Document de travail hal-04731204v1

Poster de conférence (3)

Impact of transposable elements on transcriptional diversity in stressed plants Antoine Lagarde,Axelle Costa,Camilo Pesantez,Guillaume Moissiard,Nathalie Picault International congress on transposable elements 2024, Apr 2024, Saint-malo, France Poster de conférence hal-04877850v1
The Plant Mobile Domain proteins antagonize the Polycomb group protein-mediated gene silencing Lucas Jarry,Thierry Pélissier,Margaux Olivier,Gabin Dajoux,M.N. Pouch-Pélissieret al. International congress on transposable elements 2024, Apr 2024, Saint-Malo, France Poster de conférence hal-04877181v1
Plant mobile domain proteins ensure Microrchidia 1 expression to fulfill transposon silencing Lucas Jarry,Julie Descombin,Melody Nicolau,Ange Dussutour,Nathalie Picaultet al. Epilant 2022, Jun 2022, Banyuls-sur-Mer, France. 6 (4), pp.e202201539, 2023, ⟨10.26508/lsa.202201539⟩ Poster de conférence hal-04887118v1

Communication dans un congrès (5)

The Plant Mobile Domain proteins antagonize the Polycomb group protein- mediated gene silencing Jarry Lucas,Pélissier Thierry,Olivier Margaux,Dajoux Gabin,Pouch-Pélissier M.N.et al. Plant Epigenetics - Epiplant Meeting 2024, Jul 2024, Clermont-Ferrand, France Communication dans un congrès hal-04890576v1
Transposable elements: between epigenetics and adaptive functions Guillaume Moissiard Plant Epigenetics Symposium at UCLA, Mar 2024, Los Angeles (CA), United States Communication dans un congrès hal-04888989v1
Transposable elements: between epigenetic repression and adaptive function in plants. Guillaume Moissiard GDR Mobil-ET annual meeting, Dec 2023, Paris, France Communication dans un congrès hal-04889591v1
Plant mobile domain proteins ensure Microrchidia 1 expression to fulfill transposon silencing Lucas Jarry,Julie Descombin,Melody Nicolau,Ange Dussutour,Nathalie Picaultet al. CNET 2023 GDR Mobil-ET, Jul 2023, Perpignan, France. pp.e202201539, ⟨10.26508/lsa.202201539⟩ Communication dans un congrès hal-04889559v1
Role of Plant Mobile Domain proteins in the regulation of gene expression Guillaume Moissiard Abcam Chromatin and Epigenetics meeting: Inheritance and Design, Apr 2019, Munich, France Communication dans un congrès hal-04889611v1

HDR (1)

Complex interplay between exapted transposable element proteins and epigenetic mechanisms in the regulation of gene expression and silencing of DNA repeats in plants Guillaume Moissiard Life Sciences [q-bio]. UPVD, 2020 HDR tel-03037768v1