Guillaume Viault

Publications

Article dans une revue (31)

Chemical constituents from the latex of Garcinia parvifolia and their anti-Unfolded Protein Response activity Dimitri Bréard,Thomas Charpentier,Anne-Marie Le Ray,Nadège Blon,Nelly Bataillé-Simoneauet al. Phytochemistry, 2025, pp.114522. ⟨10.1016/j.phytochem.2025.114522⟩ Article dans une revue hal-05051921v1
Xanthone Inhibitors of Unfolded Protein Response Isolated from Calophyllum caledonicum Marine Chambaud,Anne-Marie Le Ray,Racha Hamzi,Thomas Charpentier,Nadège Blonet al. Journal of Natural Products, 2024, 87 (6), pp.1628-1634. ⟨10.1021/acs.jnatprod.4c00328⟩ Article dans une revue (article de synthèse) hal-04611532v1
A new boronate ester-based crosslinking strategy allows the design of nonswelling and long-term stable dynamic covalent hydrogels N. Lagneau,L. Terriac,P. Tournier,J-J. Helesbeux,Guillaume Viaultet al. Biomaterials Science, 2023, Biomaterials Science, 11 (6), pp.2033-2045. ⟨10.1039/D2BM01690G⟩ Article dans une revue hal-03991398v1
Natural Products Targeting the Fungal Unfolded Protein Response as an Alternative Crop Protection Strategy Thomas Charpentier,Guillaume Viault,Anne-Marie Le Ray,Nelly Bataillé-Simoneau,Jean-Jacques Helesbeuxet al. Journal of Agricultural and Food Chemistry, 2023, 71 (37), pp.13706-13716. ⟨10.1021/acs.jafc.3c03602⟩ Article dans une revue hal-04208459v1
Analogues of Natural Chalcones as Efficient Inhibitors of AKR1C3 Gabriele Möller,Veronika Temml,Antonio Cala Peralta,Océane Gruet,Pascal Richommeet al. Metabolites, 2022, 12 (2), pp.99. ⟨10.3390/metabo12020099⟩ Article dans une revue hal-03782968v1
Analogues of Natural Chalcones as Efficient Inhibitors of AKR1C3 Gabriele Möller,Veronika Temml,Antonio Cala Peralta,Océane Gruet,Pascal Richommeet al. Metabolites, 2022, 12 (2), pp.99. ⟨10.3390/metabo12020099⟩ Article dans une revue hal-03716164v1
Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages Christian Kretzer,Paul Jordan,Katharina P.L. Meyer,Daniel Hoff,Markus Werneret al. Biochemical Pharmacology, 2022, 195, pp.114825. ⟨10.1016/j.bcp.2021.114825⟩ Article dans une revue hal-03533844v1
Photochemical Transformations of Chalcone-Vitamin E Hybrids Jimmy Josué Ceballos-Cruz,Jean-Jacques Helesbeux,Guillaume Viault,Denis Seraphin,Gumersindo Mirón-Lópezet al. Journal of the Mexican Chemical Society, 2022, 66 (1), ⟨10.29356/jmcs.v66i1.1670⟩ Article dans une revue hal-03533848v1
Semisynthetic Vitamin E Derivatives as Potent Antibacterial Agents against Resistant Gram‐Positive Pathogens Guillaume Viault,Marie Kempf,Alexia Ville,Khaled Alsabil,Rodolphe Perrotet al. ChemMedChem, 2021, 16 (5), pp.881-890. ⟨10.1002/cmdc.202000792⟩ Article dans une revue hal-03191789v1
Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation Konstantin Neukirch,Khaled Alsabil,Chau-Phi Dinh,Rossella Bilancia,Martin Raaschet al. Journal of Medicinal Chemistry, 2021, 64 (15), pp.11496-11526. ⟨10.1021/acs.jmedchem.1c00806⟩ Article dans une revue hal-03783673v1
Real-Time Analysis of Polyphenol-Protein Interactions by Surface Plasmon Resonance Using Surface-Bound Polyphenols Daniela Mélanie Delannoy López,Dong Tien Tran,Guillaume Viault,Sofiane Dairi,Philippe Alexandre Peixotoet al. Chemistry - A European Journal, In press, ⟨10.1002/chem.202005187⟩ Article dans une revue hal-03374449v1
Structure-based design, semi-synthesis and anti-inflammatory activity of tocotrienolic amides as 5-lipoxygenase inhibitors Chau-Phi Dinh,Alexia Ville,Konstantin Neukirch,Guillaume Viault,Veronika Temmlet al. European Journal of Medicinal Chemistry, 2020, 202, pp.112518. ⟨10.1016/j.ejmech.2020.112518⟩ Article dans une revue hal-02884134v1
MixONat, a Software for the Dereplication of Mixtures Based on 13 C NMR Spectroscopy Antoine Bruguière,Séverine Derbré,Joël Dietsch,Jules Leguy,Valentine Rahieret al. Analytical Chemistry, 2020, 92 (13), pp.8793-8801. ⟨10.1021/acs.analchem.0c00193⟩ Article dans une revue hal-03783604v1
Efficient Semi-Synthesis of Natural δ-( R )-Tocotrienols from a Renewable Vegetal Source Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,David Guilet,Pascal Richommeet al. Journal of Natural Products, 2019, 82 (1), pp.51-58. ⟨10.1021/acs.jnatprod.8b00517⟩ Article dans une revue hal-02358466v1
Concise semisynthesis of novel phenazine-vitamin E hybrids via regioselective tocopheryl ortho-quinone formation Guillaume Viault,Jean-Jacques Helesbeux,Pascal Richomme,Denis Seraphin Tetrahedron Letters, 2018, 59 (27), pp.2627-2630. ⟨10.1016/j.tetlet.2018.05.011⟩ Article dans une revue hal-02521254v1
Additional Insights into Hypericum perforatum Content: Isolation, Total Synthesis, and Absolute Configuration of Hyperbiphenyls A and B from Immunomodulatory Root Extracts Dimitri Bréard,Guillaume Viault,Marie-Charlotte Mezier,Sylvain Pagie,Antoine Bruguièreet al. Journal of Natural Products, 2018, 81 (8), pp.1850-1859. ⟨10.1021/acs.jnatprod.8b00325⟩ Article dans une revue inserm-02157665v1
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase Helmut Pein,Alexia Ville,Simona Pace,Veronika Temml,Ulrike Garschaet al. Nature Communications, 2018, 9 (1), pp.3834. ⟨10.1038/s41467-018-06158-5⟩ Article dans une revue hal-02521285v1
Efficient ortho-formylation in vitamin E series, application to the semi-synthesis of natural 5- and 7-formyl-δ-tocotrienols revealing an unprecedented 5-bromo-7-formyl exchange Khaled Alsabil,Guillaume Viault,Sorphon Suor-Cherer,Jean-Jacques Helesbeux,Joumaa Merzaet al. Tetrahedron, 2017, 73 (49), pp.6863-6870. ⟨10.1016/j.tet.2017.10.039⟩ Article dans une revue hal-02521270v1
Asymmetric dearomative spirolactonization of naphthols using λ3-iodanes under chiral phase-transfer catalysis Kevin Antien,Guillaume Viault,Laurent Pouységu,Philippe Peixoto,Stephane Quideau Tetrahedron, 2017, 73 (26), pp.3684-3690. ⟨10.1016/j.tet.2017.04.028⟩ Article dans une revue hal-02873460v1
Asymmetric dearomative spirolactonization of naphthols using λ3-iodanes under chiral phase-transfer catalysis Kevin Antien,Guillaume Viault,Laurent Pouységu,Philippe Peixoto,Stéphane Quideau Tetrahedron, 2017, 73 (26), pp.3684-3690. ⟨10.1016/j.tet.2017.04.028⟩ Article dans une revue hal-03034015v1
Design and validation of the first cell-impermeant melatonin receptor agonist Florence Gbahou,Erika Cecon,Guillaume Viault,Romain Gerbier,Frédéric Jean-Alphonseet al. British Journal of Pharmacology, 2017, 174 (14), pp.2409-2421. ⟨10.1111/bph.13856⟩ Article dans une revue hal-02873466v1
Design, synthesis and biological evaluation of fluorescent ligands for MT 1 and/or MT 2 melatonin receptors G. Viault,S. Poupart,S. Mourlevat,C. Lagaraine,S. Devavryet al. RSC Advances, 2016, 6 (67), pp.62508-62521. ⟨10.1039/C6RA10812A⟩ Article dans une revue hal-03170796v1
Semisynthetic and Natural Garcinoic Acid Isoforms as New mPGES-1 Inhibitors Khaled Alsabil,Sorphon Suor-Cherer,Andreas Koeberle,Guillaume Viault,Alexis Lavaudet al. Planta Medica, 2016, 82 (11/12), pp.1110-1116. ⟨10.1055/s-0042-108739⟩ Article dans une revue hal-01391940v1
Stereoselective Synthesis of a Bicyclic Norsesquiterpene Backbone - A Possible Route to Nardosinane Derivatives Ouassila Selaimia-Ferdjani,Anirban Kar,Sambhaji P. Chavan,Maxime Horeau,Guillaume Viaultet al. European Journal of Organic Chemistry, 2013, 2013 (31), pp.7083-7094. ⟨10.1002/ejoc.201301087⟩ Article dans une revue istex hal-02142396v1
The first &quot;ready-to-use&quot; benzene-based heterotrifunctional cross-linker for multiple bioconjugation. Guillaume Viault,Sébastien Dautrey,Nicolas Maindron,Julie Hardouin,Pierre-Yves Renardet al. Organic & Biomolecular Chemistry, 2013, 11 (16), pp.2693-2705. ⟨10.1039/c3ob40086g⟩ Article dans une revue hal-00996541v1
Hemisynthesis of selected embelin analogs and investigation of their proapoptotic activity against cancer cells Guillaume Viault,Katragadda Suresh Babu,Fabien Gautier,Sophie Barillé-Nion,Philippe Juinet al. Medicinal Chemistry (Shāriqah (United Arab Emirates)), 2013, 9 (8), pp.1028--1034. ⟨10.2174/1573406411309080003⟩ Article dans une revue istex hal-01147397v1
Synthesis of a Focused Chemical Library Based on Derivatives of Embelin, a Natural Product with Proapoptotic and Anticancer Properties Guillaume Viault,Danielle Gree,Saibal Das,Jhillu Singh Yadav,René Grée European Journal of Organic Chemistry, 2011, 2011 (7), pp.1233-1241 (avec couverture du journal). ⟨10.1002/ejoc.201190012⟩ Article dans une revue istex hal-00842650v1
Mitochondrial targeting by use of lipid nanocapsules loaded with SV30, an analogue of the small-molecule Bcl-2 inhibitor HA14-1. M. Weyland,F. Manero,A. Paillard,Danielle Gree,Guillaume Viaultet al. Journal of Controlled Release, 2011, 151 (1), pp.74-82. ⟨10.1016/j.jconrel.2010.11.032⟩ Article dans une revue istex hal-00842655v1
Synthesis of new selected analogues of the proapoptotic and anticancer molecule HA 14-1. D. Grée,S. Vorin,V.L. Manthati,F. Caijo,G. Viaultet al. Tetrahedron Letters, 2008, 49, pp.3276-3278 Article dans une revue hal-00323433v1
Synthesis of novel polyhydroxylated tetrahydropyranopyrroles S. Naud,Muriel Pipelier,C. Chaumette,G. Viault,François Huetet al. SYNLETT, 2007, 3, pp.403-406 Article dans une revue hal-00320962v1
Synthesis of polyhydroxylated pyrano-pyrrole derivatives from carbohydrate precursors S. Naud,M. Pipelier,G. Viault,A. Adjou,François Huetet al. European Journal of Organic Chemistry, 2007, pp.3296. ⟨10.1002/ejoc.200700102⟩ Article dans une revue istex hal-00383767v1

Communication dans un congrès (11)

Anti-inflammatory activity of vitamin E derivatives Chau-Phi Dinh,Alexia Ville,Barbe Anaïs,Thuy-Linh To,Konstantin Neukirchet al. Journée Des Doctorants de l’ED EGAAL, Jul 2019, Rennes, France Communication dans un congrès hal-02795186v1
Structure-based modeling, semisynthesis and biological evaluations of garcinoic acid derivatives Chau-Phi Dinh,Alexia Ville,Barbe Anaïs,Thuy-Linh To,Konstantin Neukirchet al. Journée Des Doctorants de la SFR QUASAV, Oct 2019, Angers, France Communication dans un congrès hal-02794835v1
MixONat: Assistance aux analyses déréplicatives par RMN-13C Séverine Derbré,Antoine Bruguière,Joël Dietsch,J. Leguy,V Rahieret al. Journée Scientifique Biogenouest « Du phénome au métabolome », Oct 2019, Angers, France Communication dans un congrès hal-02871151v1
Molecular docking, semisynthesis and biological evaluations of garcinoic acid amides as 5-lipoxygenase inhibitors Chau-Phi Dinh,Alexia Ville,Barbe Anaïs,Thuy-Linh To,Konstantin Neukirchet al. 27th Annual GP2A Medicinal Chemistry Conference, Aug 2019, Nottingham, United Kingdom. pp.179, ⟨10.3390/ph12040179⟩ Communication dans un congrès hal-02794994v1
Design, semisynthesis and biological evaluations of garcinoic acid derivatives as novel anti-inflammatory agents Chau-Phi Dinh,Guillaume Viault,Andreas Koeberle,Hermann Stuppner,Daniela Schusteret al. 25th Young Research Fellows Meeting, Mar 2018, Orléans, France Communication dans un congrès hal-02796904v1
Hémisynthèse d’analogues originaux de la vitamine E à visée anti-inflammatoire Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,Denis Seraphin Journée des doctorants de la SFR QUASAV, 10e édition, Oct 2017, Angers, France Communication dans un congrès hal-02864455v1
Towards pharmacologically active tocotrienol derivatives starting from δ-garcinoic acid as a common natural precursor Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,Denis Seraphin 24th Young Research Fellow’s Meeting, Feb 2017, Châtenay-Malabry, France Communication dans un congrès hal-02864430v1
Semisynthetic pathways starting from δ-garcinoic acid towards anti-inflammatory tocotrienols isolated from New Caledonian endemic plants Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,Denis Seraphin 5th AFERP International Conference "Pharmacognosy from here and there", Jul 2017, Angers, France Communication dans un congrès hal-02864451v1
Towards an Alternative to NSAIDs Based on Vitamin E Analogues Jean-Jacques Helesbeux,Khaled Alsabil,Alexia Ville,Sorphon Suor-Cherer,Guillaume Viaultet al. 25th Conference of GP2A, Aug 2017, Liverpool, United Kingdom. pp.97, ⟨10.3390/ph10040097⟩ Communication dans un congrès hal-02797756v1
Hémisynthèse de nouveaux analogues de la vitamine E à visée anti-inflammatoire Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,Denis Seraphin Séminaire recherche du département Pharmacie, Faculté de Santé, Université d’Angers, Sep 2016, Angers, France Communication dans un congrès hal-02864459v1
Design, synthesis and biological evaluation of fluorescent ligands for MT1 and/or MT2 melatonin receptors G. Viault,S. Poupart,S. Mourvelat,Christine Lagaraine,Séverine Devavryet al. 24. Conference of the Groupement des Pharmacochimistes de l'Arc Atlantique (GP2A), Université d'Angers (UA). FRA., Aug 2016, Angers, France Communication dans un congrès hal-01603651v1

Poster de conférence (17)

From Phloridzin towards Semisynthetic Bioactive Dihydrochalcones Antonio Cala Peralta,Fabian Mayr,Guillaume Viault,Veronika Temml,Daniela Schusteret al. 27th Annual GP2A Medicinal Chemistry Conference, Aug 2019, Notthingham, United Kingdom. Pharmaceuticals, 12 (4), pp.179, 2019, ⟨10.3390/ph12040179⟩ Poster de conférence hal-02798004v1
SEMISYNTHESIS OF BIOACTIVE C-BENZYLATED DIHYDROCHALCONES FROM RENEWABLE SOURCES Antonio Cala Peralta,Fabian Mayr,Guillaume Viault,Veronika Temml,Daniela Schusteret al. RICT 2019 - Interfacing Chemical Biology and Drug Discovery - 55th International Conference on Medicinal Chemistry, Jul 2019, Nantes, France Poster de conférence hal-02798163v1
Anti-inflammatory activity of w-oxidized tocotrienols Chau-Phi Dinh,Alexia Ville,Anaïs Barbe,Thuy Linh To,Guillaume Viaultet al. 26th Young Research Fellows Meeting, Feb 2019, Paris, France Poster de conférence hal-02796842v1
Semisynthetic pathways starting from δ-garcinoic acid towards anti-inflammatory tocotrienols isolated from New Caledonian endemic plants Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,Denis Seraphin Journées des doctorants de la SFR QUASAV, 11ème édition, Oct 2018, Angers, France Poster de conférence hal-02864443v1
Semisynthesis of δ-(R)-tocotrienols Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,David Guilet,Pascal Richommeet al. 8ème Symposium Francophone de Synthèse Totale, May 2018, Bordeaux, France Poster de conférence hal-02797021v1
Extraction and purification of antifungal xanthones from Garcinia mangostana (Clusiaceae) Guillaume Viault,Sorphon Suor-Cherer,Dimitri Bréard,Chau-Phi Dinh,Blon Nadègeet al. 3ème Symposium International AFERP-STOLON, Jul 2018, Rennes, France Poster de conférence hal-02795479v1
Xanthone derivatives from NPs library as potential UPR inhibitors for alternative crop protection: Molecular modelling and biological activity Guillaume Viault,Dimitri Bréard,Chau-Phi Dinh,Blon Nadège,Antoine Bruguièreet al. 30th International Symposium on the Chemistry of Natural Products, Nov 2018, Athens, Greece Poster de conférence hal-02861017v1
Semisynthetic pathways towards anti-inflammatory tocotrienols isolated from new-caledonian endemic plants Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,Denis Seraphin,Pascal Richomme 14a. RIIPN (14a Reunión Internacional de Productos Naturales), May 2018, Cuernavaca Morelos, Mexico Poster de conférence hal-02864440v1
Synthèse et évaluation biologique de nouveaux actifs potentiels ciblant les dysfonctionnements mitochondriaux Guillaume Viault,Abdel Benamar,Morgane Le Mao,R. Andriantsitohaina,Jean-Jacques Helesbeuxet al. Journée thématique de la SFR ICAT, May 2018, Angers, France Poster de conférence hal-02797199v1
α-amplexichromanol, a vitamin E semisynthetic analog – Valorization of its anti-inflammatory potential Alexia Ville,Khaled Alsabil,Guillaume Viault,David Guilet,Jean-Jacques Helesbeuxet al. Journée thématique de la SFR ICAT4208, May 2018, Angers, France Poster de conférence hal-02864434v1
Extraction and Purification of δ-Tocotrienol from Bixa orellana and Semi-Synthesis of 7-Formyl-δ-tocotrienol Khaled Alsabil,Sorphon Suor-Cherer,H. Y. Lam,Guillaume Viault,Jean-Jacques Helesbeuxet al. 25th Conference of GP2A, Aug 2017, Liverpool, United Kingdom. Pharmaceuticals, 10 (4), pp.97, 2017, ⟨10.3390/ph10040097⟩ Poster de conférence hal-02797856v1
Semisynthetics Pathways Starting from δ-Garcinoic Acid towards Anti-Inflammatory Tocotrienols Isolated from New-Caledonian Endemic Plants Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,Denis Seraphin 25th Conference of GP2A, Aug 2017, Liverpool, United Kingdom. Pharmaceuticals, 10 (4), pp.97, 2017, ⟨10.3390/ph10040097⟩ Poster de conférence hal-02797913v1
Total synthesis and determination of the absolute configuration of Hyperbiphenyl A and B, isolated from the roots of Hypericum perforatum Dimitri Bréard,Guillaume Viault,Antoine Bruguière,Béatrice Charreau,Pascal Richommeet al. 5th AFERP International Conference "Pharmacognosy from here and there", Jul 2017, Angers, France. Poster de conférence hal-02521277v1
Design, synthesis and biological evaluation of fluorescent ligands for MT1 and/or MT2 melatonin receptors Guillaume Viault,Séverine Poupart,Sophie Mourlevat,Christine Lagaraine,Séverine Devavryet al. 25. Conference of the Groupement des Pharmacochimistes de l'Arc Atlantique (GP2A), Aug 2016, Angers, France. Pharmaceuticals, 10 (1), pp.17, 2017, ⟨10.3390/ph10010017⟩ Poster de conférence hal-03448840v1
δ-garcinoic acid, a platform to tocotrienol derivatives isolated from barks of New Caledonian endemics plants Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,Denis Seraphin 5e journées scientifiques de l’école doctorale VENAM, Nov 2016, Nantes, France Poster de conférence hal-02864424v1
mPGES-1 as a New Target for Garcinoic Acid Isoforms Khaled Alsabil,Sorphon Suor-Cherer,Andreas Koeberle,Guillaume Viault,Daniela Schusteret al. The 24th Conference” of the Groupement des Pharmacochimistes de l’Arc Atlantique (GP2A), Aug 2016, Angers, France. Pharmaceuticals, 10 (1), pp.17, 2017, ⟨10.3390/ph10010017⟩ Poster de conférence hal-02797636v1
δ-Garcinoic Acid, a Convenient Natural Precursor to the Attractive δ-Tocotrienol Alexia Ville,Guillaume Viault,Jean-Jacques Helesbeux,Denis Seraphin The 24th Conference” of the Groupement des Pharmacochimistes de l’Arc Atlantique (GP2A), Aug 2016, Angers, France. Pharmaceuticals, 10 (1), pp.17, 2017, ⟨10.3390/ph10010017⟩ Poster de conférence hal-02797528v1

Brevet (1)

Heterotetrafunctional reagents for bioconjugate chemistry Guillaume Viault,Sébastien Dautrey,Pierre-Yves Renard,Anthony Romieu France, Patent n° : EP14 50478. 2014 Brevet hal-01150305v1