Gulnara Yusupova

Publications

Article dans une revue (57)

Atomic insights reveal fidelity mechanisms of eukaryotic protein synthesis Nemanja Milicevic,Lasse Jenner,Alexander Myasnikov,Marat Yusupov,Gulnara Yusupova Comptes Rendus. Biologies, 2025, 348 (G1), pp.149-157. ⟨10.5802/crbiol.180⟩ Article dans une revue hal-05336592v1
Mechanism of read-through enhancement by aminoglycosides and mefloquine Olga Kolosova,Yury Zgadzay,Artem Stetsenko,Anastasia Sukhinina,Anastasia Atamaset al. Proceedings of the National Academy of Sciences of the United States of America, 2025, 122 (17), ⟨10.1073/pnas.2420261122⟩ Article dans une revue hal-05343828v1
Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents Jidong Zhang,Christine Lair,Christine Roubert,Kwame Amaning,María Belén Barrioet al. Cell, 2023, 186 (5), pp.1013-1025.e24. ⟨10.1016/j.cell.2023.01.043⟩ Article dans une revue hal-04266217v1
mRNA reading frame maintenance during eukaryotic ribosome translocation Nemanja Milicevic,Lasse Jenner,Alexander Myasnikov,Marat Yusupov,Gulnara Yusupova Nature, In press, ⟨10.1038/s41586-023-06780-4⟩ Article dans une revue hal-04323477v1
E-site drug specificity of the human pathogen Candida albicans ribosome Yury Zgadzay,Olga Kolosova,Artem Stetsenko,Cheng Wu,David Bruchlenet al. Science Advances , 2022, 8 (21), pp.eabn1062. ⟨10.1126/sciadv.abn1062⟩ Article dans une revue hal-03813407v1
Accuracy mechanism of eukaryotic ribosome translocation Muminjon Djumagulov,Natalia Demeshkina,Lasse Jenner,Alexey Rozov,Marat Yusupovet al. Nature, 2021, 600 (7889), pp.543-546. ⟨10.1038/s41586-021-04131-9⟩ Article dans une revue hal-03800932v1
A Path to the Atomic-Resolution Structures of Prokaryotic and Eukaryotic Ribosomes Gulnara Yusupova,Marat Yusupov Биохимия / Biochemistry, 2021, 86 (8), pp.926-941. ⟨10.1134/S0006297921080046⟩ Article dans une revue hal-03365744v1
Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy: A Structural Perspective Gulnara Yusupova,Simone Pellegrino,Salvatore Terrosu,Marat Yusupov Cancers, 2021, 13, ⟨10.3390/cancers13174392⟩ Article dans une revue hal-03372921v1
NMR and crystallographic structural studies of the Elongation factor P from Staphylococcus aureus Aleksandr Golubev,Bulat Fatkhullin,Azat Gabdulkhakov,Aydar Bikmullin,Liliya Nurullinaet al. European Biophysics Journal, 2020, 49 (3-4), pp.223-230. ⟨10.1007/s00249-020-01428-x⟩ Article dans une revue hal-03668016v1
Mechanism of ribosome shutdown by RsfS in Staphylococcus aureus revealed by integrative structural biology approach Iskander Khusainov,Bulat Fatkhullin,Simone Pellegrino,Aydar Bikmullin,Wen-Ti Liuet al. Nature Communications, 2020, 11 (1), pp.1656. ⟨10.1038/s41467-020-15517-0⟩ Article dans une revue inserm-02649160v1
Posttranslational modification of Elongation Factor P from Staphylococcus aureus Gulnara Yusupova,Alexander Golubev,Luc Negroni,Filipp Krasnovid,Shamil Validovet al. FEBS Open Bio, 2020, 10 (7), pp.1342-1347. ⟨10.1002/2211-5463.12901⟩ Article dans une revue hal-02997686v1
Cryo‐EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution Alexander Golubev,Bulat Fatkhullin,Iskander Khusainov,Lasse Jenner,Azat Gabdulkhakovet al. FEBS Letters, 2020, 594 (21), pp.3551 - 3567. ⟨10.1002/1873-3468.13915⟩ Article dans une revue hal-03373743v1
Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome Gulnara Yusupova,Simone Pellegrino,Mélanie Meyer,Zef Könst,Mikael Holmet al. Nucleic Acids Research, 2019, 47 (6), pp.3223-3232. ⟨10.1093/nar/gkz053⟩ Article dans une revue hal-03365753v1
The multiple flavors of GoU pairs in RNA Eric Westhof,Marat Yusupov,Gulnara Yusupova Journal of Molecular Recognition, 2019, pp.e2782. ⟨10.1002/jmr.2782⟩ Article dans une revue hal-02361230v1
Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction Alexey Rozov,Iskander Khusainov,Kamel El Omari,Ramona Duman,Vitaliy Mykhaylyket al. Nature Communications, 2019, 10 (1), pp.2519. ⟨10.1038/s41467-019-10409-4⟩ Article dans une revue hal-03659834v1
Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome Simone Pellegrino,Mélanie Meyer,Zef Könst,Mikael Holm,Vamsee Vooraet al. Nucleic Acids Research, 2019, 47 (6), pp.3223-3232. ⟨10.1093/nar/gkz053⟩ Article dans une revue hal-03659840v1
Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria Alexey Rozov,Philippe Wolff,Henri Grosjean,Marat Yusupov,Gulnara Yusupovaet al. Nucleic Acids Research, 2018, 46 (14), pp.7425-7435. ⟨10.1093/nar/gky547⟩ Article dans une revue hal-03659841v1
Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance Simone Pellegrino,Natalia Demeshkina,Eder Mancera-Martinez,Sergey Melnikov,Angelita Simonettiet al. Journal of Molecular Biology, 2018, 430 (17), pp.2677-2687. ⟨10.1016/j.jmb.2018.06.006⟩ Article dans une revue istex hal-02294851v1
The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth Simone Pellegrino,Mélanie Meyer,Christiane Zorbas,Soumaya Bouchta,Kritika Sarafet al. Structure, 2018, 26 (3), pp.416-425.e4. ⟨10.1016/j.str.2018.01.009⟩ Article dans une revue hal-03661103v1
Aminoglycoside interactions and impacts on the eukaryotic ribosome Gulnara Yusupova,Irina Prokhorova,Roger Altman,Muminjon Djumagulov,Jaya Shresthaet al. Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (51), pp.E10899-E10908. ⟨10.1073/pnas.1715501114⟩ Article dans une revue hal-03365761v1
Structure of the 70S ribosome from human pathogen Staphylococcus aureus Iskander Khusainov,Quentin Vicens,Anthony Bochler,François Grosse,Alexander Myasnikovet al. Nucleic Acids Research, 2017, 45 (2), pp.1026-1026. ⟨10.1093/nar/gkw1126⟩ Article dans une revue hal-02171293v1
Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF Iskander Khusainov,Quentin Vicens,Rustam Ayupov,Konstantin Usachev,Alexander Myasnikovet al. EMBO Journal, 2017, 36 (14), pp.2073-2087. ⟨10.15252/embj.201696105⟩ Article dans une revue hal-03661109v1
Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A Brandon Mcclary,Boris Zinshteyn,Mélanie Meyer,Morgan Jouanneau,Simone Pellegrinoet al. Cell Chemical Biology, 2017, 24 (5), pp.605-613.e5. ⟨10.1016/j.chembiol.2017.04.006⟩ Article dans une revue hal-03661121v1
Crystal structure of eukaryotic ribosome and its complexes with inhibitors Gulnara Yusupova,Marat Yusupov Philosophical Transactions of the Royal Society B: Biological Sciences, 2017, 372 (1716), pp.20160184. ⟨10.1098/rstb.2016.0184⟩ Article dans une revue hal-03661123v1
Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides Zef Könst,Anne Szklarski,Simone Pellegrino,Sharon Michalak,Mélanie Meyeret al. Nature Chemistry, 2017, 9 (11), pp.1140-1149. ⟨10.1038/nchem.2800⟩ Article dans une revue hal-03659848v1
Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome Sergey Melnikov,Justine Mailliot,Byung-Sik Shin,Lukas Rigger,Gulnara Yusupovaet al. Journal of Molecular Biology, 2016, 428 (18), pp.3570-3576. ⟨10.1016/j.jmb.2016.05.011⟩ Article dans une revue hal-03661136v1
Eukaryotic Ribosome as a Target for Cardiovascular Disease Simone P Pellegrino,Gulnara Yusupova Cell Chemical Biology, 2016, 17 (23), pp.1319-1321. ⟨10.1016/j.chembiol.2016.11.004⟩ Article dans une revue inserm-01415698v1
Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome Irina Prokhorova,Kseniya Akulich,Desislava Makeeva,Ilya Osterman,Dmitry Skvortsovet al. Scientific Reports, 2016, 6 (1), pp.27720. ⟨10.1038/srep27720⟩ Article dans une revue hal-03661134v1
Molecular insights into protein synthesis with proline residues Sergey Melnikov,Justine Mailliot,Lukas Rigger,Sandro Neuner,Byung‐sik Shinet al. EMBO Reports, 2016, 17 (12), pp.1776-1784. ⟨10.15252/embr.201642943⟩ Article dans une revue hal-03661132v1
Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code Alexey Rozov,Natalia Demeshkina,Iskander Khusainov,Eric Westhof,Marat M. Yusupovet al. Nature Communications, 2016, 7 (1), pp.10457. ⟨10.1038/ncomms10457⟩ Article dans une revue hal-02294521v1
The ribosome prohibits the G•U wobble geometry at the first position of the codon–anticodon helix Alexey Rozov,Eric Westhof,Marat M. Yusupov,Gulnara Yusupova Nucleic Acids Research, 2016, 44 (13), pp.6434-6441. ⟨10.1093/nar/gkw431⟩ Article dans une revue hal-02294675v1
New Structural Insights into Translational Miscoding Alexey Rozov,Natalia Demeshkina,Eric Westhof,Marat M. Yusupov,Gulnara Yusupova Trends in Biochemical Sciences, 2016, 41 (9), pp.798-814. ⟨10.1016/j.tibs.2016.06.001⟩ Article dans une revue istex hal-02294531v1
A glimpse on Staphylococcus aureus translation machinery and its control Iskander Khusainov,Alessandra Marenna,Marie Cerciat,Pierre Fechter,Yaser Hashemet al. Молекулярная биология / Molecular Biology, 2016, 50 (4), pp.549-557. ⟨10.7868/S0026898416040042⟩ Article dans une revue hal-02294244v1
Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency Justine Mailliot,Nicolas Garreau de Loubresse,Gulnara Yusupova,Arturas Meskauskas,Jonathan Dinmanet al. Journal of Molecular Biology, 2016, 428 (10), pp.2195-2202. ⟨10.1016/j.jmb.2016.02.013⟩ Article dans une revue hal-03661143v1
Structural insights into the translational infidelity mechanism Alexey Rozov,Natalia Demeshkina,Eric Westhof,Marat Yusupov,Gulnara Yusupova Nature Communications, 2015, 6 (1), pp.7251. ⟨10.1038/ncomms8251⟩ Article dans une revue hal-03661150v1
Insights into the origin of the nuclear localization signals in conserved ribosomal proteins Sergey Melnikov,Adam Ben-Shem,Gulnara Yusupova,Marat Yusupov Nature Communications, 2015, 6 (1), pp.7382. ⟨10.1038/ncomms8382⟩ Article dans une revue hal-03661149v1
Ribosome biochemistry in crystal structure determination Gulnara Yusupova,Marat Yusupov RNA, 2015, 21 (4), pp.771-773. ⟨10.1261/rna.050039.115⟩ Article dans une revue hal-03661153v1
Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism Eric Westhof,Marat Yusupov,Gulnara Yusupova F1000Prime Reports, 2014, 6, pp.19. ⟨10.12703/P6-19⟩ Article dans une revue hal-03661156v1
High-Resolution Structure of the Eukaryotic 80S Ribosome Gulnara Yusupova,Marat Yusupov Annual Review of Biochemistry, 2014, 83 (1), pp.467-486. ⟨10.1146/annurev-biochem-060713-035445⟩ Article dans une revue hal-03661159v1
Structural basis for the inhibition of the eukaryotic ribosome Nicolas Garreau de Loubresse,Irina Prokhorova,Wolf Holtkamp,Marina Rodnina,Gulnara Yusupovaet al. Nature, 2014, 513 (7519), pp.517-522. ⟨10.1038/nature13737⟩ Article dans une revue hal-03661154v1
Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis Lasse Jenner,Agata Starosta,Daniel Terry,Aleksandra Mikolajka,Liudmila Filonavaet al. Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (10), pp.3812-3816. ⟨10.1073/pnas.1216691110⟩ Article dans une revue hal-03661163v1
New structural insights into the decoding mechanism: Translation infidelity via a G·U pair with Watson-Crick geometry Natalia Demeshkina,Lasse Jenner,Eric Westhof,Marat Yusupov,Gulnara Yusupova FEBS Letters, 2013, 587 (13), pp.1848-1857. ⟨10.1016/j.febslet.2013.05.009⟩ Article dans une revue hal-03661161v1
A new understanding of the decoding principle on the ribosome Natalia Demeshkina,Lasse Jenner,Eric Westhof,Marat Yusupov,Gulnara Yusupova Nature, 2012, 484 (7393), pp.256-259. ⟨10.1038/nature10913⟩ Article dans une revue istex hal-03661168v1
One core, two shells: bacterial and eukaryotic ribosomes Sergey Melnikov,Adam Ben-Shem,Nicolas Garreau de Loubresse,Lasse Jenner,Gulnara Yusupovaet al. Nature Structural and Molecular Biology, 2012, 19 (6), pp.560-567. ⟨10.1038/nsmb.2313⟩ Article dans une revue istex hal-03661166v1
Crystal structure of the 80S yeast ribosome Lasse Jenner,Sergey Melnikov,Nicolas Garreau de Loubresse,Adam Ben-Shem,Madina Iskakovaet al. Current Opinion in Structural Biology, 2012, 22 (6), pp.759-767. ⟨10.1016/j.sbi.2012.07.013⟩ Article dans une revue istex hal-03661164v1
The Structure of the Eukaryotic Ribosome at 3.0 Å Resolution Adam Ben Shem,Nicolas Garreau de Loubresse,Sergey Melnikov,Lasse Jenner,Gulnara Yusupovaet al. Science, 2011, 334 (6062), pp.1524-1529. ⟨10.1126/science.1212642⟩ Article dans une revue hal-03661170v1
Structural rearrangements of the ribosome at the tRNA proofreading step Lasse Jenner,Natalia Demeshkina,Gulnara Yusupova,Marat Yusupov Nature Structural and Molecular Biology, 2010, 17 (9), pp.1072-1078. ⟨10.1038/nsmb.1880⟩ Article dans une revue istex hal-03661174v1
Interactions of the ribosome with mRNA and tRNA Natalia Demeshkina,Lasse Jenner,Gulnara Yusupova,Marat Yusupov Current Opinion in Structural Biology, 2010, 20 (3), pp.325-332. ⟨10.1016/j.sbi.2010.03.002⟩ Article dans une revue istex hal-03661179v1
Structural aspects of messenger RNA reading frame maintenance by the ribosome Lasse Jenner,Natalia Demeshkina,Gulnara Yusupova,Marat Yusupov Nature Structural and Molecular Biology, 2010, 17 (5), pp.555-560. ⟨10.1038/nsmb.1790⟩ Article dans une revue istex hal-03661176v1
Crystal Structure of the Eukaryotic Ribosome Adam Ben-Shem,Lasse Jenner,Gulnara Yusupova,Marat Yusupov Science, 2010, 330 (6008), pp.1203-1209. ⟨10.1126/science.1194294⟩ Article dans une revue hal-03661172v1
Ribosomal initiation complexes probed by toeprinting and effect of trans-acting translational regulators in bacteria. Pierre Fechter,Clément Chevalier,Gulnara Yusupova,Marat M. Yusupov,Pascale Rombyet al. Methods in Molecular Biology, 2009, 540, pp.247-63. ⟨10.1007/978-1-59745-558-9_18⟩ Article dans une revue hal-00391772v1
A structural view of translation initiation in bacteria. Angelita Simonetti,Stefano Marzi,L. Jenner,Alexander Myasnikov,Pascale Rombyet al. Cellular and Molecular Life Sciences, 2009, 66 (3), pp.423-36. ⟨10.1007/s00018-008-8416-4⟩ Article dans une revue hal-00391779v1
Messenger RNA conformations in the ribosomal E site revealed by X-ray crystallography. Lasse Jenner,Bernard Rees,Marat M. Yusupov,Gulnara Yusupova EMBO Reports, 2007, 8 (9), pp.846-50. ⟨10.1038/sj.embor.7401044⟩ Article dans une revue hal-00189152v1
Structural basis for messenger RNA movement on the ribosome. Gulnara Yusupova,Lasse Jenner,Bernard Rees,Dino Moras,Marat M. Yusupov Nature, 2006, 444 (7117), pp.391-4. ⟨10.1038/nature05281⟩ Article dans une revue istex hal-00188236v1
Translational operator of mRNA on the ribosome: how repressor proteins exclude ribosome binding. Lasse Jenner,Pascale Romby,Bernard Rees,Clemens Schulze-Briese,Mathias Springeret al. Science, 2005, 308 (5718), pp.120-3. ⟨10.1126/science.1105639⟩ Article dans une revue hal-00187636v1
Conformational transition of initiation factor 2 from the GTP- to GDP-bound state visualized on the ribosome. Alexander G Myasnikov,Stefano Marzi,Angelita Simonetti,Anna Maria Giuliodori,Claudio O Gualerziet al. Nature Structural and Molecular Biology, 2005, 12 (12), pp.1145-9. ⟨10.1038/nsmb1012⟩ Article dans une revue istex hal-00187706v1
Topography of the Escherichia coli Initiation Factor 2/fMet-tRNAfMet Complex as Studied by Cross-Linking Gulnara Yusupova,Joseph Reinbolt,Hiroshi Wakao,Soumaya Laalami,Marianne Grunberg-Managoet al. Biochemistry, 1996, 35 (9), pp.2978-2984. ⟨10.1021/bi9519415⟩ Article dans une revue istex hal-05259817v1

Chapitre d'ouvrage (3)

Reconstitution of Functionally Active Thermus thermophilus 30S Ribosomal Subunit from Ribosomal 16S RNA and Ribosomal Proteins Sultan Agalarov,Marat Yusupov,Gulnara Yusupova Nucleic Acid Crystallography, 1320, Springer New York, pp.303-314, 2016, Methods in Molecular Biology, ⟨10.1007/978-1-4939-2763-0_19⟩ Chapitre d'ouvrage hal-03661148v1
X-Ray Analysis of Prokaryotic and Eukaryotic Ribosomes Lasse Jenner,Adam Ben-Shem,Natalia Demeshkina,Marat Yusupov,Gulnara Yusupova Biophysical approaches to translational control of gene expression, Springer New York, pp.1-25, 2012, ⟨10.1007/978-1-4614-3991-2_1⟩ Chapitre d'ouvrage hal-04994108v1
Interaction of bacterial ribosomes with mRNA and tRNA as studied by X-ray crystallographic analysis Lasse Jenner,Natalia Demeshkina,Gulnara Yusupova,Marat Yusupov Ribosomes, Springer Vienna, pp.45-55, 2011, ⟨10.1007/978-3-7091-0215-2_4⟩ Chapitre d'ouvrage hal-04996139v1