Guy Lippens

Identifiants chercheurs

IdHAL :

guy-lippens

ORCID :

0000-0002-8236-0901

IdRef :

061529613

Présentation

Publications

Article dans une revue (102)

MultiNMRFit: a software to fit 1D and pseudo-2D NMR spectra Pierre Millard,Loïc Le Grégam,Svetlana Dubiley,Valeria Gabrielli,Thomas Gosselin-Monplaisiret al. Bioinformatics, 2025, 41 (9), ⟨10.1093/bioinformatics/btaf463⟩ Article dans une revue hal-05322487v1
Backbone and Methyl resonance assignment of an active PETase Jelena Grga,Emmanuelle Boll,Guy Lippens,Cyril Charlier Biomolecular NMR Assignments, 2025, 20 (1), pp.3. ⟨10.1007/s12104-025-10250-5⟩ Article dans une revue hal-05350439v1
Multinuclear non-haem iron-dependent oxidative enzymes: landscape of their substrates, partner proteins and biosynthetic gene clusters R. Antoine,L. Leprevost,S. Jünger,S. Zirah,G. Lippenset al. Microbial Genomics, 2025, 11 (7), pp.001462. ⟨10.1099/mgen.0.001462⟩ Article dans une revue hal-05244524v1
Towards site-specific information on PET degrading enzymes using NMR near operational temperature Valeria Gabrielli,Jelena Grga,Sabine Gavalda,Laura Perrot,François-Xavier Cantrelleet al. Scientific Reports, 2025, 15 (1), pp.38602. ⟨10.1038/s41598-025-22351-1⟩ Article dans une revue hal-05350480v1
Bacillus subtilis utilizes decarboxylated S-adenosylmethionine for the biosynthesis of tandem aminopropylated microcin C, a potent inhibitor of bacterial aspartyl-tRNA synthetase Alexey Kulikovsky,Eldar Yagmurov,Anastasiia Grigoreva,Aleksandr Popov,Konstantin Severinovet al. Journal of the American Chemical Society, In press, ⟨10.1021/jacs.4c18468⟩ Article dans une revue hal-05014998v1
A widespread family of ribosomal peptide metallophores involved in bacterial adaptation to metal stress Laura Leprevost,Sophie Jünger,Guy Lippens,Céline Guillaume,Giuseppe Sicoliet al. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (49), pp.e2408304121. ⟨10.1073/pnas.2408304121⟩ Article dans une revue hal-04811059v1
New route to a pyrazoline scaffold featuring original substitutions and its crystal structure Guy Lippens,Nicolas Jean-Bart,Emmanuel Gras Chemical Monthly = Monatshefte für Chemie, 2024, 155 (2), pp.183-188. ⟨10.1007/s00706-023-03169-x⟩ Article dans une revue hal-04669669v1
The structure of a Tau fragment bound to tubulin prompts new hypotheses on Tau mechanism and oligomerization Liza Ammar Khodja,Valérie Campanacci,Guy Lippens,Benoît Gigant PNAS Nexus, 2024, ⟨10.1093/pnasnexus/pgae487⟩ Article dans une revue hal-04771509v1
Exploring the pH dependence of an improved PETase Cyril Charlier,Sabine Gavalda,Jelena Grga,Laura Perrot,Valeria Gabrielliet al. Biophysical Journal, In press, ⟨10.1016/j.bpj.2024.04.026⟩ Article dans une revue hal-04569437v1
Biochemical characterization of a SusD-like protein involved in β-1,3-glucan utilization by an uncultured cow rumen Bacteroides Xiaoqian Li,Guy Lippens,Jean-Luc Parrou,Gianluca Cioci,Jérémy Esqueet al. MSphere, 2024, 9 (8), ⟨10.1128/msphere.00278-24⟩ Article dans une revue hal-04743213v1
Catalytic enantiospecific deuteration of complex amino acid mixtures with ruthenium nanoparticles Gabriel Mencia,Pauline Rouan,Pier-Francesco Fazzini,Hanna Kulyk,Victor Varela-Izquierdoet al. Catalysis Science & Technology, 2024, 14 (17), pp.4904-4911. ⟨10.1039/D4CY00588K⟩ Article dans une revue hal-04778743v1
Structural and Biochemical Characterization of a Nonbinding SusD-Like Protein Involved in Xylooligosaccharide Utilization by an Uncultured Human Gut &lt;i&gt;Bacteroides&lt;/i&gt; Strain Alexandra Tauzin,Zhi Wang,Gianluca Cioci,Xiaoqian Li,Aurore Labourelet al. MSphere, 2023, 7 (5), ⟨10.1128/msphere.00244-22⟩ Article dans une revue hal-03796391v1
An NMR look at an engineered PET depolymerase Cyril Charlier,Sabine Gavalda,Vinciane Borsenberger,Sophie Duquesne,Alain Martyet al. Biophysical Journal, In press, 121 (15), pp.2882-2894. ⟨10.1016/j.bpj.2022.07.002⟩ Article dans une revue hal-03739009v1
Characterization of a Family of Scorpion Toxins Modulating Ca2+-Activated Cl− Current in Vascular Myocytes Jean-Luc Morel,Nathalie Mokrzycki,Guy Lippens,Hervé Drobecq,Pierre Sautièreet al. Toxins, 2022, 14 (11), pp.780. ⟨10.3390/toxins14110780⟩ Article dans une revue hal-03864126v1
Proline-Rich Region II (PRR2) Plays an Important Role in Tau–Glycan Interaction: An NMR Study Anqesha Murray,Lufeng Yan,James Gibson,Jian Liu,David Eliezeret al. Biomolecules, 2022, 12 (11), pp.1573. ⟨10.3390/biom12111573⟩ Article dans une revue (data paper) hal-03832416v1
The Jo-In protein welding system is a relevant tool to create CBM-containing plant cell wall degrading enzymes Louise Badruna,Vincent Burlat,Pierre Roblin,Thomas Enjalbert,Guy Lippenset al. New Biotechnology, 2021, 65, pp.31-41. ⟨10.1016/j.nbt.2021.07.004⟩ Article dans une revue hal-03340154v1
Improved NMR Detection of Phospho-Metabolites in a Complex Mixture Neil Cox,Pierre Millard,Cyril Charlier,Guy Lippens Analytical Chemistry, 2021, 93 (11), pp.4818-4824. ⟨10.1021/acs.analchem.0c04056⟩ Article dans une revue hal-03171690v2
Virtual decoupling to break the simplification versus resolution trade-off in nuclear magnetic resonance of complex metabolic mixtures Cyril Charlier,Neil Cox,Sophie Prud'Homme,Alain Geffard,Jean-Marc Nuzillardet al. Magnetic Resonance, 2021, 2, pp.619-627. ⟨10.5194/mr-2-619-2021⟩ Article dans une revue hal-03338624v1
IsoSolve: An Integrative Framework to Improve Isotopic Coverage and Consolidate Isotopic Measurements by Mass Spectrometry and/or Nuclear Magnetic Resonance Pierre Millard,Serguei Sokol,Michael Kohlstedt,Christoph Wittmann,Fabien Létisseet al. Analytical Chemistry, 2021, 93 (27), pp.9428-9436. ⟨10.1021/acs.analchem.1c01064⟩ Article dans une revue hal-03307270v1
The covalent complex of Jo-In results from a long-lived, non-covalent intermediate state with near-native structure Neil Cox,Cyril Charlier,Ramadoss Vijayaraj,Marion de La Mare,Sophie Barbeet al. Biochemical and Biophysical Research Communications, 2021, 589, pp.223-228. ⟨10.1016/j.bbrc.2021.12.028⟩ Article dans une revue hal-03554277v1
Identification and characterization of andalusicin: N-terminally dimethylated class III lantibiotic from Bacillus thuringiensis sv. andalousiensis Anastasiia Grigoreva,Julia Andreeva,Dmitry Bikmetov,Anastasiia Rusanova,Marina Serebryakovaet al. iScience, 2021, 24 (5), ⟨10.1016/j.isci.2021.102480⟩ Article dans une revue hal-03270626v1
The Zebra Mussel (Dreissena polymorpha) as a Model Organism for Ecotoxicological Studies: A Prior 1H NMR Spectrum Interpretation of a Whole Body Extract for Metabolism Monitoring Sophie Martine Prud’homme,Younes Mohamed Ismail Hani,Neil Cox,Guy Lippens,Jean-Marc Nuzillardet al. Metabolites, 2020, 10 (6), pp.256. ⟨10.3390/metabo10060256⟩ Article dans une revue hal-02934872v1
Increasing field strength versus advanced isotope labeling for NMR based fluxomics Mickael Dinclaux,Edern Cahoreau,Pierre Millard,Fabien Letisse,Guy Lippens Magnetic Resonance in Chemistry, 2020, pp.1-7. ⟨10.1002/mrc.4988⟩ Article dans une revue hal-02438088v1
Integrated pH Measurement during Reaction Monitoring with Dual-Reception 1 H– 31 P NMR Spectroscopy Neil Cox,Rainer Kuemmerle,Pierre Millard,Edern Cahoreau,Jean-Marie Françoiset al. Analytical Chemistry, 2019, 91 (6), pp.3959-3963. ⟨10.1021/acs.analchem.8b05147⟩ Article dans une revue hal-02131891v1
Elucidating Tau function and dysfunction in the era of cryo-EM Guy Lippens,Benoît Gigant Journal of Biological Chemistry, In press, 294 (24), pp.9316-9325. ⟨10.1074/jbc.REV119.008031⟩ Article dans une revue hal-02137974v1
Efficient in vivo synthesis of lasso peptide pseudomycoidin proceeds in the absence of both the leader and the leader peptidase Tatyana Zyubko,Marina Serebryakova,Julia Andreeva,Mikhail Metelev,Guy Lippenset al. Chemical Science, 2019, 10 (42), pp.9699-9707. ⟨10.1039/C9SC02370D⟩ Article dans une revue hal-02368109v1
Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication Marie Dujardin,Vanesa Madan,Neha S Gandhi,François-Xavier Cantrelle,Hélène Launayet al. Journal of Biological Chemistry, 2019, 294 (35), pp.13171-13185. ⟨10.1074/jbc.RA119.009537⟩ Article dans une revue hal-02998113v1
Tuning the catalytic activity and selectivity of water-soluble bimetallic RuPt nanoparticles by modifying their surface metal distribution Donia Bouzouita,Guy Lippens,Edwin A Baquero,Pier-Francesco Fazzini,Grégory Pieterset al. Nanoscale, 2019, 11 (35), pp.16544-16552. ⟨10.1039/C9NR04149D⟩ Article dans une revue hal-02283913v2
Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors Clément Despres,Jing Di,François-Xavier Cantrelle,Zizheng Li,Isabelle Huventet al. ACS Chemical Biology, 2019, 14 (6), pp.1363-1379. ⟨10.1021/acschembio.9b00325⟩ Article dans une revue hal-02317189v1
Backbone chemical shift assignment of macrophage infectivity potentiator virulence factor of Trypanosoma cruzi Juan M. Lopez,Ricardo Antiparra,Guy Lippens,Mirko Zimic,Patricia Sheenet al. Biomolecular NMR Assignments, 2019, 13 (1), pp.21-25. ⟨10.1007/s12104-018-9844-1⟩ Article dans une revue hal-02170460v1
Futile Encounter Engineering of the DSR-M Dextransucrase Modifies the Resulting Polymer Length Marion Claverie,Gianluca Cioci,Matthieu Guionnet,Julia Schörghuber,Roman Lichteneckeret al. Biochemistry, 2019, 58 (25), pp.2853-2859. ⟨10.1021/acs.biochem.9b00373⟩ Article dans une revue hal-02176417v1
Efficient Access to Deuterated and Tritiated Nucleobase Pharmaceuticals and Oligonucleotides using Hydrogen-Isotope Exchange Alberto Palazzolo,Sophie Feuillastre,Viktor Pfeifer,Sébastien Garcia-Argote,Donia Bouzouitaet al. Angewandte Chemie International Edition, 2019, 58 (15), pp.4891-4895. ⟨10.1002/anie.201813946⟩ Article dans une revue cea-02075752v1
In-cell NMR: from metabolites to macromolecules Guy Lippens,Edern Cahoreau,Pierre Millard,C. Charlier,J. Lopezet al. Analyst, 2018, 143 (3), pp.620-629. ⟨10.1039/C7AN01635B⟩ Article dans une revue hal-01886451v1
The Neuronal tau protein blocks in vitro fibrillation of the amyloid-beta (A beta) peptide at the oligomeric stage Cecilia Wallin,Yoshitaka Hiruma,Sebastian K. T. S. Warmlander,Isabelle Huvent,Juri Jarvetet al. Journal of the American Chemical Society, 2018, 140 (26), pp.8138-8146. ⟨10.1021/jacs.7b13623⟩ Article dans une revue hal-02154329v1
Improved Isotopic Profiling by Pure Shift Heteronuclear 2D J -Resolved NMR Spectroscopy Davy Sinnaeve,Mickael Dinclaux,Edern Cahoreau,Pierre Millard,Jean-Charles Portaiset al. Analytical Chemistry, 2018, 90 (6), pp.4025-4031. ⟨10.1021/acs.analchem.7b05206⟩ Article dans une revue hal-02131883v1
Interaction study between HCV NS5A-D2 and NS5B using 19F NMR Marie Dujardin,François-Xavier Cantrelle,Guy Lippens,Xavier Hanoulle Journal of Biomolecular NMR, 2018, 70 (1), pp.67-76. ⟨10.1007/s10858-017-0159-9⟩ Article dans une revue hal-01886452v1
Monitoring of nanoparticle reactivity in solution: interaction of l -lysine and Ru nanoparticles probed by chemical shift perturbation parallels regioselective H/D exchange Luis Miguel Martinez-Pietro,Edwin A Baquero,Grégory Pieters,Juan Flores,Ernesto de Jesuset al. Chemical Communications, 2017, 53 (43), pp.5850-5853. ⟨10.1039/c7cc02445b⟩ Article dans une revue hal-02004103v1
Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A Aurélie Badillo,Véronique Receveur-Brechot,Stéphane Sarrazin,François-Xavier Cantrelle,Frédéric Delolmeet al. Biochemistry, 2017, 56 (24), pp.3029 - 3048. ⟨10.1021/acs.biochem.7b00212⟩ Article dans une revue hal-01785410v1
Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma Kenneth Verstraete,Frank Peelman,Harald Braun,Juan Lopez,Dries van Rompaeyet al. Nature Communications, 2017, 8 (1), 17 p. ⟨10.1038/ncomms14937⟩ Article dans une revue hal-01605011v1
Glycan Determinants of Heparin-Tau Interaction Jing Zhao,Isabelle Huvent,Guy Lippens,David Eliezer,Anqiang Q. Zhanget al. Biophysical Journal, 2017, 112 (5), pp.921-932. ⟨10.1016/j.bpj.2017.01.024⟩ Article dans une revue hal-01600157v1
Investigations on the Determinants Responsible for Low Molar Mass Dextran Formation by DSR-M Dextransucrase Marion Claverie,Gianluca Cioci,Marlène Vuillemin,Nelly Monties,Pierre Roblinet al. ACS Catalysis, 2017, 7 (10), pp.7106-7119. ⟨10.1021/acscatal.7b02182⟩ Article dans une revue hal-01886431v1
NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B Luiza Bessa,Hélène Launay,Marie Dujardin,Xavier Cantrelle,Guy Lippenset al. Journal of Biological Chemistry, 2017, 292 (44), pp.18024-18043. ⟨10.1074/jbc.M117.813766⟩ Article dans une revue hal-01620117v1
Identification of the Tau phosphorylation pattern that drives its aggregation Clement Despres,Cillian Byrne,Haoling Qi,François-Xavier Cantrelle,Isabelle Huventet al. Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (34), pp.9080 - 9085. ⟨10.1073/pnas.1708448114⟩ Article dans une revue hal-01620128v1
Metabolic phenotyping of human plasma by H-1-NMR at high and medium magnetic field strengths: a case study for lung cancer Evelyne Louis,Francois-Xavier Cantrelle,Liesbet Mesotten,Gunter Reekmans,Liene Bervoetset al. Magnetic Resonance in Chemistry, 2017, 55 (8), pp.706-713. ⟨10.1002/mrc.4577⟩ Article dans une revue hal-01886450v1
(15)N-NMR-based approach for amino acids-based (13)C-metabolic flux analysis of metabolism Pierre Millard,Edern Cahoreau,Maud Heuillet,Jean-Charles Portais,Guy Lippens Analytical Chemistry, 2017, 89 (3), pp.2101-2106. ⟨10.1021/acs.analchem.6b04767⟩ Article dans une revue hal-01602563v1
A β-Turn Motif in the Steroid Hormone Receptor’s Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52 Cillian Byrne,Morkos A. Henen,Mathilde Belnou,François-Xavier Cantrelle,Amina Kamahet al. Biochemistry, 2016, 55 (38), pp.5366 - 5376. ⟨10.1021/acs.biochem.6b00506⟩ Article dans une revue hal-01389826v1
Proline Conformation in a Functional Tau Fragment Puneet Ahuja,Xavier Cantrelle,Isabelle Huvent,Xavier Hanoulle,Juan Lopezet al. Journal of Molecular Biology, 2016, 428 (1), pp.79 - 91. ⟨10.1016/j.jmb.2015.11.023⟩ Article dans une revue istex hal-01389832v1
NMR Meets Tau: Insights into Its Function and Pathology Guy Lippens,Isabelle Landrieu,Caroline Smet,Isabelle Huvent,Neha Gandhiet al. Ancient biomolecules, 2016, 6 (2), ⟨10.3390/biom6020028⟩ Article dans une revue (article de synthèse) hal-01389829v1
Studying Intrinsically disordered proteins under true in vivo conditions by combined cross-polarization and carbonyl-detection NMR spectroscopy Juan Lopez,Robert Schneider,Francois-Xavier Cantrelle,Isabelle Huvent,Guy Lippens Angewandte Chemie International Edition, 2016, 55 (26), pp.7418-7422. ⟨10.1002/anie.201601850⟩ Article dans une revue istex hal-01886415v1
Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated Kinase Haoling Qi,Sudhakaran Prabakaran,François-Xavier Cantrelle,Béatrice Chambraud,Jeremy Gunawardenaet al. Journal of Biological Chemistry, 2016, 291 (14), pp.7742 - 7753. ⟨10.1074/jbc.M115.700914⟩ Article dans une revue hal-01389831v1
The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior. Julien Giustiniani,Kevin Guillemeau,Omar Dounane,Elodie Sardin,Isabelle Huventet al. FASEB Journal, 2015, Epub ahead of print Article dans une revue hal-01145979v1
Tau phosphorylation regulates the interaction between BIN1’s SH3 domain and Tau’s proline-rich domain Yoann Sottejeau,Alexis Bretteville,François-Xavier Cantrelle,Nicolas Malmanche,Florie Demiauteet al. Acta Neuropathologica Communications, 2015, 3 (1), ⟨10.1186/s40478-015-0237-8⟩ Article dans une revue hal-01221659v1
A Phosphorylation-Induced Turn Defines the Alzheimer's Disease AT8 Antibody Epitope on the Tau Protein. Neha S Gandhi,Isabelle Landrieu,Cillian Byrne,Predrag Kukic,Laziza Amniaiet al. Angewandte Chemie International Edition, 2015, 127 (23), pp.6923-6927 ⟨10.1002/ange.201501898⟩ Article dans une revue istex hal-01145963v1
Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy. Julien Giustiniani,Béatrice Chambraud,Elodie Sardin,Omar Dounane,Kevin Guillemeauet al. Proceedings of the National Academy of Sciences of the United States of America, 2014, pp.4584-9 Article dans une revue hal-01077897v1
Nuclear magnetic resonance analysis of the acetylation pattern of the neuronal Tau protein. Amina Kamah,Isabelle Huvent,François-Xavier Cantrelle,Haoling Qi,Guy Lippenset al. Biochemistry, 2014, 53 (18), pp.3020-32. ⟨10.1021/bi500006v⟩ Article dans une revue hal-01077868v1
Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2. Gary S Mcdowell,Christopher J Hindley,Guy Lippens,Isabelle Landrieu,Anna Philpott BMC Biochemistry, 2014, pp.24 Article dans une revue hal-01081937v1
A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge. Isabelle Huvent,Amina Kamah,François-Xavier Cantrelle,Nicolas Barois,Christian Slomiannyet al. Biochemical and Biophysical Research Communications, 2014, 445 (2), pp.299-303. ⟨10.1016/j.bbrc.2014.01.161⟩ Article dans une revue istex hal-01077911v1
Mechanism of Tau-promoted microtubule assembly as probed by NMR spectroscopy. Benoît Gigant,Isabelle Landrieu,Caroline Fauquant,Pascale Barbier,Isabelle Huventet al. Journal of the American Chemical Society, 2014, pp.12615-23 Article dans une revue hal-01077829v1
H/D exchange of a 15 N labelled Tau fragment as measured by a simple Relax-EXSY experiment Juan Lopez,Puneet Ahuja,Isabelle Landrieu,Francois-Xavier Cantrelle,Isabelle Huventet al. Journal of Magnetic Resonance, 2014, Journal of Magnetic Resonance, 249, pp.32-37. ⟨10.1016/j.jmr.2014.10.008⟩ Article dans une revue hal-03235804v1
Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker. Kunie Ando,Pierre Dourlen,Anne-Véronique Sambo,Alexis Bretteville,Karim Bélarbiet al. Neurobiol Aging, 2013, 34 (3), pp.757-69. ⟨10.1016/j.neurobiolaging.2012.08.004⟩ Article dans une revue istex hal-00765859v1
Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA. Caroline Smet-Nocca,Hélène Launay,Jean-Michel Wieruszeski,Guy Lippens,Isabelle Landrieu Journal of Biomolecular NMR, 2013, 55 (4), pp.323-37. ⟨10.1007/s10858-013-9716-z⟩ Article dans une revue istex hal-00903359v1
A new strategy for sequential assignment of intrinsically unstructured proteins based on (15)N single isotope labelling. Juan Lopez,Puneet Ahuja,Melanie Gerard,Jean-Michel Wieruszeski,Guy Lippens Journal of Magnetic Resonance, 2013, 236, pp.1-6. ⟨10.1016/j.jmr.2013.07.007⟩ Article dans une revue istex hal-00903369v1
Differential contribution of the repeats to heparin binding of HBHA, a major adhesin of Mycobacterium tuberculosis. Pierre Lebrun,Dominique Raze,Bernd Fritzinger,Jean-Michel Wieruszeski,Franck Bietet al. PLoS ONE, 2012, 7 (3), pp.e32421. ⟨10.1371/journal.pone.0032421⟩ Article dans une revue hal-00713026v1
Towards understanding the phosphorylation code of tau. Guy Lippens,Laziza Amniai,Jean-Michel Wieruszeski,Alain Sillen,Arnaud Leroyet al. Biochemical Society Transactions, 2012, 40 (4), pp.698-703. ⟨10.1042/BST20120050⟩ Article dans une revue hal-00765867v1
Hepatitis C Virus NS5B and Host Cyclophilin A share a common binding site on NS5A. Claire Rosnoblet,Bernd Fritzinger,Dominique Legrand,Hélène Launay,Jean-Michel Wieruszeskiet al. Journal of Biological Chemistry, 2012, epub ahead of print. ⟨10.1074/jbc.M112.392209⟩ Article dans une revue hal-00765873v1
Cell signaling, post-translational protein modifications and NMR spectroscopy. Francois-Xavier Theillet,Caroline Smet-Nocca,Stamatios Liokatis,Rossukon Thongwichian,Jonas Kostenet al. Journal of Biomolecular NMR, 2012, 54 (3), pp.217-36. ⟨10.1007/s10858-012-9674-x⟩ Article dans une revue hal-00765863v1
Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. Peter Borghgraef,Clément Menuet,Clara Theunis,Justin V Louis,Herman Devijveret al. PLoS ONE, 2012, pp.e84442 Article dans une revue hal-01077942v1
Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding. Sudhakaran Prabakaran,Guy Lippens,Hanno Steen,Jeremy Gunawardena Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2012, 4 (6), pp.565-83. ⟨10.1002/wsbm.1185⟩ Article dans une revue hal-00765876v1
Domain 3 of NS5A protein from the hepatitis C virus has intrinsic {alpha}-helical propensity and is a substrate of Cyclophilin A. Dries Verdegem,Aurelie Badillo,Jean-Michel Wieruszeski,Isabelle Landrieu,Arnaud Leroyet al. Journal of Biological Chemistry, 2011, epub ahead of print. ⟨10.1074/jbc.M110.182436⟩ Article dans une revue hal-00586923v1
Systematic identification of tubulin interacting fragments of the microtubule-associated protein TAU leads to a highly efficient promoter of microtubule assembly. Caroline Fauquant,Virginie Redeker,Isabelle Landrieu,Jean-Michel Wieruzseski,Dries Verdegemet al. Journal of Biological Chemistry, 2011, epub ahead of print. ⟨10.1074/jbc.M111.223545⟩ Article dans une revue hal-00618268v1
Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands Xavier Carette,Nicolas Blondiaux,Eve Willery,Sylviane Hoos,Nathalie Lecat-Guilletet al. Nucleic Acids Research, 2011, 40 (7), pp.3018 - 3030. ⟨10.1093/nar/gkr1113⟩ Article dans une revue pasteur-03525621v1
Glycerol and glycerol carbonate as ultraviscous solvents for mixture analysis by NMR. Pedro Lameiras,Leslie Boudesocque,Zéphirin Mouloungui,Jean-Hugues Renault,Jean-Michel Wieruszeskiet al. Journal of Magnetic Resonance, 2011, 212 (1), pp.161-8. ⟨10.1016/j.jmr.2011.06.021⟩ Article dans une revue istex hal-00618281v1
Intermolecular interaction studies using small volumes. David Bourry,Davy Sinnaeve,Katelijne Gheysen,Bernd Fritzinger,Gianni Vandenborreet al. Magnetic Resonance in Chemistry, 2011, 49 (1), pp.9-15. ⟨10.1002/mrc.2699⟩ Article dans une revue istex hal-00586937v1
Molecular Basis for an Ancient Partnership between Prolyl Isomerase Pin1 and Phosphatase Inhibitor-2. Furqan Sami,Caroline Smet-Nocca,Meera Khan,Isabelle Landrieu,Guy Lippenset al. Biochemistry, 2011, 50 (30), pp.6567-78. ⟨10.1021/bi200553e⟩ Article dans une revue hal-00618273v1
Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation. Caroline Smet-Nocca,Malgorzata Broncel,Jean-Michel Wieruszeski,Caroline Tokarski,Xavier Hanoulleet al. Molecular BioSystems, 2011, 7 (5), pp.1420-9. ⟨10.1039/c0mb00337a⟩ Article dans une revue hal-00586849v1
Characterization of the AT180 epitope of phosphorylated Tau protein by a combined nuclear magnetic resonance and fluorescence spectroscopy approach. Laziza Amniai,Guy Lippens,Isabelle Landrieu Biochemical and Biophysical Research Communications, 2011, epub ahead of print. ⟨10.1016/j.bbrc.2011.08.046⟩ Article dans une revue istex hal-00618266v1
Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau. Isabelle Landrieu,Caroline Smet-Nocca,Laziza Amniai,Justin Vijay Louis,Jean-Michel Wieruszeskiet al. PLoS ONE, 2011, 6 (6), pp.e21521. ⟨10.1371/journal.pone.0021521⟩ Article dans une revue hal-00618270v1
Ranking High Affinity Ligands of Low Solubility by NMR Spectroscopy Isabelle Landrieu,Xavier Hanoulle,Bernd Fritzinger,Dragos Horvath,Jean-Michel Wieruszeskiet al. ACS Medicinal Chemistry Letters, 2011, 2 (6), pp.485-487. ⟨10.1021/ml200039u⟩ Article dans une revue hal-00618277v1
Comparative analysis of Erk phosphorylation suggests a mixed strategy for measuring phospho-form distributions. Sudhakaran Prabakaran,Robert A Everley,Isabelle Landrieu,Jean-Michel Wieruszeski,Guy Lippenset al. Molecular Systems Biology, 2011, 7, pp.482. ⟨10.1038/msb.2011.15⟩ Article dans une revue hal-00586931v1
Mice lacking phosphatase PP2A subunit PR61/B'{delta} (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3{beta} Justin V Louis,Ellen Martens,Peter Borghgraef,Caroline Lambrecht,Ward Sentset al. Proceedings of the National Academy of Sciences of the United States of America, 2011, epub ahead of print. ⟨10.1073/pnas.1018777108⟩ Article dans une revue hal-00586855v1
Structural basis for the non-immunosuppressive character of the cyclosporin A analogue Debio 025. Isabelle Landrieu,Xavier Hanoulle,Fanny Bonachera,Arnaud Hamel,Nathalie Sibilleet al. Biochemistry, 2010, 49 (22), pp.4679-86. ⟨10.1021/bi1003266⟩ Article dans une revue hal-00508817v1
Spectroscopic studies of GSK3β phosphorylation of the neuronal Tau protein and its interaction with the N-terminal domain of apolipoprotein E Arnaud Leroy,Isabelle Landrieu,Isabelle Huvent,Dominique Legrand,Bernadette Coddevilleet al. Journal of Biological Chemistry, 2010, 285 (43), pp.33435-33444. ⟨10.1074/jbc.M110.149419⟩ Article dans une revue hal-00641629v1
Microtubule and MAPs: thermodynamics of complex formation by AUC, ITC, fluorescence, and NMR. François Devred,Pascale Barbier,Daniel Lafitte,Isabelle Landrieu,Guy Lippenset al. Methods in Cell Biology, 2010, 95, pp.449-480. ⟨10.1016/S0091-679X(10)95023-1⟩ Article dans une revue hal-00508818v1
DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A. Lotte Coelmont,Xavier Hanoulle,Udayan Chatterji,Carola Berger,Joke Snoecket al. PLoS ONE, 2010, 5 (10), pp.e13687. ⟨10.1371/journal.pone.0013687⟩ Article dans une revue hal-00586948v1
Hepatitis C virus NS5A protein is a substrate for the Peptidyl-Prolyl cis/trans isomerase activity of Cyclophilins A and B. Xavier Hanoulle,Aurélie Badillo,Jean-Michel Wieruszeski,Dries Verdegem,Isabelle Landrieuet al. Journal of Biological Chemistry, 2009, epub ahead of print. ⟨10.1074/jbc.M809244200⟩ Article dans une revue hal-00373457v1
Alzheimer disease specific phosphoepitopes of Tau interfere with assembly of tubulin but not binding to microtubules. Laziza Amniai,Pascale Barbier,Alain Sillen,Jean-Michel Wieruszeski,Vincent Peyrotet al. FASEB Journal, 2009, 23 (4), pp.1146-52. ⟨10.1096/fj.08-121590⟩ Article dans une revue hal-00348164v1
Selective backbone labelling of ILV methyl labelled proteins. Nathalie Sibille,Xavier Hanoulle,Fanny Bonachera,Dries Verdegem,Isabelle Landrieuet al. Journal of Biomolecular NMR, 2009, 43 (4), pp.219-27. ⟨10.1007/s10858-009-9307-1⟩ Article dans une revue istex hal-00373458v1
The talin rod IBS2 alpha helix interacts with the beta 3 integrin cytoplasmic tail membrane proximal helix by establishing charge complementary salt bridges. Sophie Rodius,Olivier Chaloin,Michèle Moes,Elisabeth Schaffner-Reckinger,Isabelle Landrieuet al. Journal of Biological Chemistry, 2008, epub ahead of print. ⟨10.1074/jbc.M709704200⟩ Article dans une revue hal-00293590v1
Sandwich-ELISE NMR: reducing the sample volume of NMR samples. Jean-Michel Wieruszeski,Bernd Fritzinger,Xavier Hanoulle,José C Martins,Guy Lippens Journal of Magnetic Resonance, 2008, 193 (1), pp.37-40. ⟨10.1016/j.jmr.2008.04.006⟩ Article dans une revue istex hal-00293593v1
Structural and functional characterisation of the interaction between cyclophilin B and A heparin derived oligosaccharide. Xavier Hanoulle,Aurélie Melchior,Nathalie Sibille,Benjamin Parent,Agnès Denyset al. Journal of Biological Chemistry, 2007, epub ahead of print. ⟨10.1074/jbc.M706353200⟩ Article dans une revue hal-00175485v1
NMR Investigation of the Interaction between the Neuronal Protein Tau and the Microtubules. Alain Sillen,Pascale Barbier,Isabelle Landrieu,Sylvie Lefebvre,Jean-Michel Wieruszeskiet al. Biochemistry, 2007, 46 (11), pp.3055-3064. ⟨10.1021/bi061920i⟩ Article dans une revue istex hal-00139673v1
Tau aggregation in Alzheimer's disease : what role for phosphorylation ? Guy Lippens,Alain Sillen,Isabelle Landrieu,Laziza Amniai,Nathalie Sibilleet al. Prion, 2007, 1 (1), pp.21-25 Article dans une revue hal-00161158v1
Contribution of rotational diffusion to pulsed field gradient diffusion measurements. Andrew J Baldwin,John Christodoulou,Paul D Barker,Christopher M Dobson,Guy Lippens The Journal of Chemical Physics, 2007, 127 (11), pp.114505. ⟨10.1063/1.2759211⟩ Article dans une revue hal-00273334v1
Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria. Xavier Hanoulle,Jean-Michel Wieruszeski,Pierre Rousselot-Pailley,Isabelle Landrieu,Camille Lochtet al. Journal of Antimicrobial Chemotherapy, 2006, 58 (4), pp.768. ⟨10.1093/jac/dkl332⟩ Article dans une revue hal-00103724v1
Pin1 allows for differential Tau dephosphorylation in neuronal cells. Malika Hamdane,Pierre Dourlen,Alexis Bretteville,Anne-Véronique Sambo,Stéphanie Ferreiraet al. Molecular and Cellular Neuroscience, 2006, 32, pp.155-160 Article dans une revue hal-00085645v1
Arabidopsis PASTICCINO2 is an antiphosphatase involved in regulation of cyclin-dependent kinase A. Marco da Costa,Liên Bach,Isabelle Landrieu,Yannick Bellec,Olivier Catriceet al. The Plant cell, 2006, 18, pp.1426-1437 Article dans une revue hal-00085654v1
Studying the natively unfolded neuronal Tau protein by solution NMR spectroscopy. Guy Lippens,Alain Sillen,Caroline Smet,Jean-Michel Wieruszeski,Arnaud Leroyet al. Protein and Peptide Letters, 2006, 13, pp.235-246 Article dans une revue hal-00085628v1
Exploring the Molecular Function of PIN1 by Nuclear Magnetic Resonance. Isabelle Landrieu,Caroline Smet,Jean-Michel Wieruszeski,Anne-Véronique Sambo,René Wintjenset al. Current Protein and Peptide Science, 2006, 7, pp.179-194 Article dans une revue hal-00085621v1
New DEFT sequences for the acquisition of one-dimensional carbon NMR spectra of small unlabelled molecules. Guy Lippens,Jean-Michel Wieruszeski,Marcel Piotto,Karim Elbayed,Marise Bourdonneau Magnetic Resonance in Chemistry, 2006, 44, pp.943-947 Article dans une revue hal-00103769v1
Osmoregulated periplasmic glucans of the free-living photosynthetic bacterium Rhodobacter sphaeroides Philippe Talaga,Virginie Cogez,Jean-Michel Wieruszeski,Bernd Stahl,Jérôme Lemoineet al. European Journal of Biochemistry, 2002, 269, pp.2464-2472 Article dans une revue hal-00021144v1
In vivo detection of the cyclic osmoregulated periplasmic glucan of Ralstonia solanacearum by high-resolution magic angle spinning NMR. Jean-Michel Wieruszeski,Anne Bohin,Jean-Pierre Bohin,Guy Lippens Journal of Magnetic Resonance, 2001, 151, pp.1-6 Article dans une revue hal-00021378v1
Recombinant production of the p10CKS1At protein from Arabidopsis thaliana and 13C and 15N double-isotopic enrichment for NMR studies I. Landrieu,P. Casteels,B. Odaert,Lieven de Veylder,D. Portetelleet al. Protein Expression and Purification, 1999, 16, pp.144-151 Article dans une revue hal-02686867v1

Communication dans un congrès (2)

Tuning the catalytic activity/selectivity of water-soluble bimetallic RuPt nanoparticles by modifying their surface metal distribution Donia Bouzouita,Simon Tricard,Luis Miguel Martinez-Pietro,Guy Lippens,Bruno Chaudret 257. National Meeting of the American-Chemical-Society (ACS), Mar 2019, Orlando, United States Communication dans un congrès hal-02274479v1
Enlarging the toolbox of GH70 sucrose-active enzymes by mixing discovery and rational engineering Claire Moulis,Marion Claverie,Manon Molina,Florent Grimaud,L. Tiruta-Barnaet al. Carbohydrate Bioengineering Meeting, May 2019, Toulouse, France Communication dans un congrès hal-04773297v1

Chapitre d'ouvrage (1)

The Study of Posttranslational Modifications of Tau Protein by Nuclear Magnetic Resonance Spectroscopy: Phosphorylation of Tau Protein by ERK2 Recombinant Kinase and Rat Brain Extract, and Acetylation by Recombinant Creb-Binding Protein Haoling Qi,Clément Despres,Sudhakaran Prabakaran,Francois-Xavier Cantrelle,Béatrice Chambraudet al. Nocca Smet, Caroline. Tau protein : methods and protocols, 1523, Springer New York, pp.179-213, 2017, 978-1-4939-6596-0. ⟨10.1007/978-1-4939-6598-4_11⟩ Chapitre d'ouvrage hal-03235823v1

Brevet (1)

Novel esterases and uses thereof Guy Lippens,Cyril Charlier,Maher Ben Khaled,Isabelle André,Marc Guéroult France, Patent n° : WO2023/088909. 2023 Brevet hal-04780356v1